Science 4 February 1994: Vol. 263. no. 5147, pp. 684 - 687 DOI: 10.1126/science.8303278

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Articles

Ubiquitination and Endocytosis of Cell Adhesion Molecule DM-GRASP Regulate Its Cell Surface Presence and Affect Its Role for Axon Navigation.

K. Thelen, T. Georg, S. Bertuch, P. Zelina, and G. E. Pollerberg (2008)
J. Biol. Chem. 283, 32792-32801
 |  Abstract »  |  Full Text »  |  PDF »

RhoB Regulates PDGFR- Trafficking and Signaling in Vascular Smooth Muscle Cells.

M. Huang, J. B. DuHadaway, G. C. Prendergast, and L. D. Laury-Kleintop (2007)
Arterioscler Thromb Vasc Biol 27, 2597-2605
 |  Abstract »  |  Full Text »  |  PDF »

Loss of T-Cell Protein Tyrosine Phosphatase Induces Recycling of the Platelet-derived Growth Factor (PDGF) beta-Receptor but Not the PDGF {alpha}-Receptor.

S. Karlsson, K. Kowanetz, A. Sandin, C. Persson, A. Ostman, C.-H. Heldin, and C. Hellberg (2006)
Mol. Biol. Cell 17, 4846-4855
 |  Abstract »  |  Full Text »  |  PDF »

The Smaller Isoforms of Ankyrin 3 Bind to the p85 Subunit of Phosphatidylinositol 3'-Kinase and Enhance Platelet-derived Growth Factor Receptor Down-regulation.

A. Ignatiuk, J. P. Quickfall, A. D. Hawrysh, M. D. Chamberlain, and D. H. Anderson (2006)
J. Biol. Chem. 281, 5956-5964
 |  Abstract »  |  Full Text »  |  PDF »

Phosphoinositide-derived messengers in endocrine signaling.

T Balla (2006)
J. Endocrinol. 188, 135-153
 |  Abstract »  |  Full Text »  |  PDF »

Role of Phosphoinositide 3-Kinase Regulatory Isoforms in Development and Actin Rearrangement.

S. M. Brachmann, C. M. Yballe, M. Innocenti, J. A. Deane, D. A. Fruman, S. M. Thomas, and L. C. Cantley (2005)
Mol. Cell. Biol. 25, 2593-2606
 |  Abstract »  |  Full Text »  |  PDF »

The p85{alpha} Subunit of Phosphatidylinositol 3'-Kinase Binds to and Stimulates the GTPase Activity of Rab Proteins.

M. D. Chamberlain, T. R. Berry, M. C. Pastor, and D. H. Anderson (2004)
J. Biol. Chem. 279, 48607-48614
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase C-{zeta} and Protein Kinase B Regulate Distinct Steps of Insulin Endocytosis and Intracellular Sorting.

F. Fiory, F. Oriente, C. Miele, C. Romano, A. Trencia, A. T. Alberobello, I. Esposito, R. Valentino, F. Beguinot, and P. Formisano (2004)
J. Biol. Chem. 279, 11137-11145
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase B/Akt Acts via Glycogen Synthase Kinase 3 To Regulate Recycling of {alpha}v{beta}3 and {alpha}5{beta}1 Integrins.

M. S. Roberts, A. J. Woods, T. C. Dale, P. van der Sluijs, and J. C. Norman (2004)
Mol. Cell. Biol. 24, 1505-1515
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of the Platelet-derived Growth Factor Receptor-beta and Epidermal Growth Factor Receptor by G Protein-coupled Receptor Kinase-2. MECHANISMS FOR SELECTIVITY OF DESENSITIZATION.

N. J. Freedman, L. K. Kim, J. P. Murray, S. T. Exum, L. Brian, J.-H. Wu, and K. Peppel (2002)
J. Biol. Chem. 277, 48261-48269
 |  Abstract »  |  Full Text »  |  PDF »

A Monoclonal Antibody to Visualize PtdIns(3,4,5)P3 in Cells.

R. Chen, V. H. Kang, J. Chen, J. C. Shope, J. Torabinejad, D. B. DeWald, and G. D. Prestwich (2002)
J. Histochem. Cytochem. 50, 697-708
 |  Abstract »  |  Full Text »  |  PDF »

A novel costimulatory signaling in human T lymphocytes by a splice variant of CD28.

H. Hanawa, Y. Ma, S. A. Mikolajczak, M. L. Charles, T. Yoshida, R. Yoshida, C. A. Strathdee, D. W. Litchfield, and A. Ochi (2002)
Blood 99, 2138-2145
 |  Abstract »  |  Full Text »  |  PDF »

Recruitment of the Class II Phosphoinositide 3-Kinase C2{beta} to the Epidermal Growth Factor Receptor: Role of Grb2.

M. Wheeler and J. Domin (2001)
Mol. Cell. Biol. 21, 6660-6667
 |  Abstract »  |  Full Text »  |  PDF »

p110-related PI 3-kinases regulate phagosome-phagosome fusion and phagosomal pH through a PKB/Akt dependent pathway in Dictyostelium.

A. Rupper, J. Rodriguez-Paris, B. Grove, and J. Cardelli (2001)
J. Cell Sci. 114, 1283-1295
 |  Abstract »  |  PDF »

Sodium-Potassium-Adenosinetriphosphatase-Dependent Sodium Transport in the Kidney: Hormonal Control.

E. Feraille and A. Doucet (2001)
Physiol Rev 81, 345-418
 |  Abstract »  |  Full Text »  |  PDF »

Transformation of Mortal Human Fibroblasts and Activation of a Growth Inhibitory Pathway by the Bovine Papillomavirus E5 Oncoprotein.

L. M. Petti and F. A. Ray (2000)
Cell Growth Differ. 11, 395-408
 |  Abstract »  |  Full Text »

Requirement of Phosphatidylinositol 3-Kinase Activity for Translocation of Exogenous aFGF to the Cytosol and Nucleus.

O. Klingenberg, A. Wiedlocha, L. Citores, and S. Olsnes (2000)
J. Biol. Chem. 275, 11972-11980
 |  Abstract »  |  Full Text »  |  PDF »

The Class II Phosphoinositide 3-Kinase PI3K-C2alpha Is Concentrated in the Trans-Golgi Network and Present in Clathrin-coated Vesicles.

J. Domin, I. Gaidarov, M. E. K. Smith, J. H. Keen, and M. D. Waterfield (2000)
J. Biol. Chem. 275, 11943-11950
 |  Abstract »  |  Full Text »  |  PDF »

Role of the PI3K/PKB signaling pathway in cAMP-mediated translocation of rat liver Ntcp.

C. R. L. Webster and M. S. Anwer (1999)
Am J Physiol Gastrointest Liver Physiol 277, G1165-G1172
 |  Abstract »  |  Full Text »  |  PDF »

Identification of the Receptor-associated Signaling Enzymes That Are Required for Platelet-derived Growth Factor-AA-dependent Chemotaxis and DNA Synthesis.

S. Rosenkranz, K. A. DeMali, J. A. Gelderloos, C. Bazenet, and A. Kazlauskas (1999)
J. Biol. Chem. 274, 28335-28343
 |  Abstract »  |  Full Text »  |  PDF »

Mechanism of Action and In Vivo Role of Platelet-Derived Growth Factor.

C.-H. Heldin and B. Westermark (1999)
Physiol Rev 79, 1283-1316
 |  Abstract »  |  Full Text »  |  PDF »

Augmentation of CTLA-4 expression by wortmannin: involvement of lysosomal sorting properties of CTLA-4.

S. Oki, T. Kohsaka, and M. Azuma (1999)
Int. Immunol. 11, 1563-1571
 |  Abstract »  |  Full Text »  |  PDF »

Short-Term Pravastatin Mediates Growth Inhibition and Apoptosis, Independently of Ras, via the Signaling Proteins p27Kip1 and PI3 Kinase.

R. H. WEISS, A. RAMIREZ, and A. JOO (1999)
J. Am. Soc. Nephrol. 10, 1880-1890
 |  Abstract »  |  Full Text »

Phosphoinositide-Ap-2 Interactions Required for Targeting to Plasma Membrane Clathrin-Coated Pits.

I. Gaidarov and J. H. Keen (1999)
J. Cell Biol. 146, 755-764
 |  Abstract »  |  Full Text »  |  PDF »

Synergistic Role of the Phosphatidylinositol 3-Kinase and Mitogen-Activated Protein Kinase Cascade in the Regulation of Insulin Receptor Trafficking.

T. Sasaoka, T. Wada, H. Ishihara, Y. Takata, T. Haruta, I. Usui, M. Ishiki, and M. Kobayashi (1999)
Endocrinology 140, 3826-3834
 |  Abstract »  |  Full Text »

Integrins Enhance Platelet-derived Growth Factor (PDGF)-dependent Responses by Altering the Signal Relay Enzymes That Are Recruited to the PDGF beta Receptor.

K. A. DeMali, E. Balciunaite, and A. Kazlauskas (1999)
J. Biol. Chem. 274, 19551-19558
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for Apical Endocytosis in Polarized Hepatic Cells: Phosphoinositide 3-Kinase Inhibitors Lead to the Lysosomal Accumulation of Resident Apical Plasma Membrane Proteins.

P. L. Tuma, C. M. Finnegan, J.-H. Yi, and A. L. Hubbard (1999)
J. Cell Biol. 145, 1089-1102
 |  Abstract »  |  Full Text »  |  PDF »

Transduction of Basolateral-to-Apical Signals across Epithelial Cells: Ligand-stimulated Transcytosis of the Polymeric Immunoglobulin Receptor Requires Two Signals.

F. Luton and K. E. Mostov (1999)
Mol. Biol. Cell 10, 1409-1427
 |  Abstract »  |  Full Text »

Phosphoinositide 3-Kinases and Their FYVE Domain-containing Effectors as Regulators of Vacuolar/Lysosomal Membrane Trafficking Pathways.

A. E. Wurmser, J. D. Gary, and S. D. Emr (1999)
J. Biol. Chem. 274, 9129-9132
 |  Full Text »  |  PDF »

Deletion of a Critical Internalization Domain in the G-CSFR in Acute Myelogenous Leukemia Preceded by Severe Congenital Neutropenia.

M. G. Hunter and B. R. Avalos (1999)
Blood 93, 440-446
 |  Abstract »  |  Full Text »  |  PDF »

Bile acid secretion and direct targeting of mdr1-green fluorescent protein from Golgi to the canalicular membrane in polarized WIF-B cells.

Y Sai, A. Nies, and I. Arias (1999)
J. Cell Sci. 112, 4535-4545
 |  Abstract »  |  PDF »

The Box-1 Region of the Leukemia Inhibitory Factor Receptor alpha -Chain Cytoplasmic Domain Is Sufficient for Hemopoietic Cell Proliferation and Differentiation.

Y. Zhang, T. Willson, D. Metcalf, D. Cary, D. J. Hilton, R. Clark, and N. A. Nicola (1998)
J. Biol. Chem. 273, 34370-34383
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Roles for the p110{alpha} and hVPS34 Phosphatidylinositol 3'-Kinases in Vesicular Trafficking, Regulation of the Actin Cytoskeleton, and Mitogenesis.

U. Siddhanta, J. McIlroy, A. Shah, Y. Zhang, and J. M. Backer (1998)
J. Cell Biol. 143, 1647-1659
 |  Abstract »  |  Full Text »  |  PDF »

Stimulation of IRS-1-associated Phosphatidylinositol 3-Kinase and Akt/Protein Kinase B but Not Glucose Transport by beta 1-Integrin Signaling in Rat Adipocytes.

A. Guilherme and M. P. Czech (1998)
J. Biol. Chem. 273, 33119-33122
 |  Abstract »  |  Full Text »  |  PDF »

Insulin Receptor Substrate-1 and Phosphatidylinositol 3-Kinase Regulate Extracellular Signal-Regulated Kinase-Dependent and -Independent Signaling Pathways during Myogenic Differentiation.

D. D. Sarbassov and C. A. Peterson (1998)
Mol. Endocrinol. 12, 1870-1878
 |  Abstract »  |  Full Text »

The Role of Phosphoinositide 3-Kinase in Taurocholate-induced Trafficking of ATP-dependent Canalicular Transporters in Rat Liver.

S. Misra, P. Ujhazy, Z. Gatmaitan, L. Varticovski, and I. M. Arias (1998)
J. Biol. Chem. 273, 26638-26644
 |  Abstract »  |  Full Text »  |  PDF »

Transduction pathways involved in rapid hormone receptor regulation in the mammary epithelium.

F. F. Bolander Jr. (1998)
Am J Physiol Endocrinol Metab 275, E553-E557
 |  Abstract »  |  Full Text »  |  PDF »

The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha.

S. Miyake, M. L. Lupher Jr., B. Druker, and H. Band (1998)
PNAS 95, 7927-7932
 |  Abstract »  |  Full Text »  |  PDF »

Full Activation of the Platelet-derived Growth Factor beta -Receptor Kinase Involves Multiple Events.

R. M. Baxter, J. P. Secrist, R. R. Vaillancourt, and A. Kazlauskas (1998)
J. Biol. Chem. 273, 17050-17055
 |  Abstract »  |  Full Text »  |  PDF »

Endobrevin, a Novel Synaptobrevin/VAMP-Like Protein Preferentially Associated with the Early Endosome.

S. H. Wong, T. Zhang, Y. Xu, V. N. Subramaniam, G. Griffiths, and W. Hong (1998)
Mol. Biol. Cell 9, 1549-1563
 |  Abstract »  |  Full Text »

PDGF-induced glycosaminoglycan synthesis is mediated via phosphatidylinositol 3-kinase.

J. Liu, D. Fitzli, M. Liu, I. Tseu, I. Caniggia, D. Rotin, and M. Post (1998)
Am J Physiol Lung Cell Mol Physiol 274, L702-L713
 |  Abstract »  |  Full Text »  |  PDF »

CD28 Receptor Endocytosis Is Targeted by Mutations That Disrupt Phosphatidylinositol 3-Kinase Binding and Costimulation.

D. Cefai, H. Schneider, O. Matangkasombut, H. Kang, J. Brody, and C. E. Rudd (1998)
J. Immunol. 160, 2223-2230
 |  Abstract »  |  Full Text »  |  PDF »

Wortmannin Retards the Movement of the Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor and Its Ligand out of Endosomes.

R. Kundra and S. Kornfeld (1998)
J. Biol. Chem. 273, 3848-3853
 |  Abstract »  |  Full Text »  |  PDF »

Syntaxin 7, a Novel Syntaxin Member Associated with the Early Endosomal Compartment.

S. H. Wong, Y. Xu, T. Zhang, and W. Hong (1998)
J. Biol. Chem. 273, 375-380
 |  Abstract »  |  Full Text »  |  PDF »

Disruption of Dictyostelium PI3K genes reduces [32P]phosphatidylinositol 3,4 bisphosphate and [32P]phosphatidylinositol trisphosphate levels, alters F-actin distribution and impairs pinocytosis.

K Zhou, S Pandol, G Bokoch, and A. Traynor-Kaplan (1998)
J. Cell Sci. 111, 283-294
 |  Abstract »  |  PDF »

PI-3-kinase and MAPK regulate mesangial cell proliferation and migration in response to PDGF.

G. G. Choudhury, C. Karamitsos, J. Hernandez, A. Gentilini, J. Bardgette, and H. E. Abboud (1997)
Am J Physiol Renal Physiol 273, F931-F938
 |  Abstract »  |  Full Text »  |  PDF »

Phosphatidylinositol 3-Kinase and Ca2+ Influx Dependence for Ligand-stimulated Internalization of the c-Kit Receptor.

J. L. Gommerman, R. Rottapel, and S. A. Berger (1997)
J. Biol. Chem. 272, 30519-30525
 |  Abstract »  |  Full Text »  |  PDF »

Differentiation and Transforming Growth Factor-beta Receptor Down-regulation by Collagen-alpha 2beta 1 Integrin Interaction Is Mediated by Focal Adhesion Kinase and Its Downstream Signals in Murine Osteoblastic Cells.

Y. Takeuchi, M. Suzawa, T. Kikuchi, E. Nishida, T. Fujita, and T. Matsumoto (1997)
J. Biol. Chem. 272, 29309-29316
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Calcium-independent Mannose 6-Phosphate Receptor Incorporation into trans-Golgi Network-derived Clathrin-coated Vesicles by Wortmannin.

P. Gaffet, A. T. Jones, and M. J. Clague (1997)
J. Biol. Chem. 272, 24170-24175
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of CTLA-4 with AP50, a clathrin-coated pit adaptor protein.

Y. Zhang and J. P. Allison (1997)
PNAS 94, 9273-9278
 |  Abstract »  |  Full Text »  |  PDF »

Hrs, a Tyrosine Kinase Substrate with a Conserved Double Zinc Finger Domain, Is Localized to the Cytoplasmic Surface of Early Endosomes.

M. Komada, R. Masaki, A. Yamamoto, and N. Kitamura (1997)
J. Biol. Chem. 272, 20538-20544
 |  Abstract »  |  Full Text »  |  PDF »

Identification of an early endosomal protein regulated by phosphatidylinositol 3-kinase.

V. Patki, J. Virbasius, W. S. Lane, B.-H. Toh, H. S. Shpetner, and S. Corvera (1997)
PNAS 94, 7326-7330
 |  Abstract »  |  Full Text »  |  PDF »

Insulin Receptor Substrate (IRS)-2 Is Dephosphorylated More Rapidly than IRS-1 via Its Association with Phosphatidylinositol 3-Kinase in Skeletal Muscle Cells.

T. Ogihara, B.-C. Shin, M. Anai, H. Katagiri, K. Inukai, M. Funaki, Y. Fukushima, H. Ishihara, K. Takata, M. Kikuchi, et al. (1997)
J. Biol. Chem. 272, 12868-12873
 |  Abstract »  |  Full Text »  |  PDF »

Role of the Basic, Proline-rich Region of Dynamin in Src Homology 3Domain Binding and Endocytosis.

P. M. Okamoto, J. S. Herskovits, and R. B. Vallee (1997)
J. Biol. Chem. 272, 11629-11635
 |  Abstract »  |  Full Text »  |  PDF »

Inactivation of Two Dictyostelium discoideum Genes, DdPIK1 and DdPIK2, Encoding Proteins Related to Mammalian Phosphatidylinositide 3-kinases, Results in Defects in Endocytosis, Lysosome to Postlysosome Transport, and Actin Cytoskeleton Organization.

G. Buczynski, B. Grove, A. Nomura, M. Kleve, J. Bush, R. A. Firtel, and J. Cardelli (1997)
J. Cell Biol. 136, 1271-1286
 |  Abstract »  |  Full Text »  |  PDF »

Specific Increase in p85alpha Expression in Response to Dexamethasone Is Associated with Inhibition of Insulin-like Growth Factor-I Stimulated Phosphatidylinositol 3-Kinase Activity in Cultured Muscle Cells.

F. Giorgino, M. T. Pedrini, L. Matera, and R. J. Smith (1997)
J. Biol. Chem. 272, 7455-7463
 |  Abstract »  |  Full Text »  |  PDF »

Subsets of Epidermal Growth Factor Receptors during Activation and Endocytosis.

D. R. Emlet, D. K. Moscatello, L. B. Ludlow, and A. J. Wong (1997)
J. Biol. Chem. 272, 4079-4086
 |  Abstract »  |  Full Text »  |  PDF »

Morphological effects of wortmannin on the endosomal system and GLUT4-containing compartments in rat adipose cells.

D Malide and S. Cushman (1997)
J. Cell Sci. 110, 2795-2806
 |  Abstract »  |  PDF »

Selective Recognition of Phosphatidylinositol 3,4,5-Trisphosphate by a Synthetic Peptide.

P.-J. Lu and C.-S. Chen (1997)
J. Biol. Chem. 272, 466-472
 |  Abstract »  |  Full Text »  |  PDF »

Formation of c-Cbl·Phosphatidylinositol 3-Kinase Complexes on Lymphocyte Membranes by a p56lck-independent Mechanism.

D. Hartley and S. Corvera (1996)
J. Biol. Chem. 271, 21939-21943
 |  Abstract »  |  Full Text »  |  PDF »

A Functional Phosphatidylinositol 3,4,5-Trisphosphate/Phosphoinositide Binding Domain in the Clathrin Adaptor AP-2 alpha Subunit. IMPLICATIONS FOR THE ENDOCYTIC PATHWAY.

I. Gaidarov, Q. Chen, J. R. Falck, K. K. Reddy, and J. H. Keen (1996)
J. Biol. Chem. 271, 20922-20929
 |  Abstract »  |  Full Text »  |  PDF »

Phosphatidylinositol-3' Kinase Is Not Required for Mitogenesis or Internalization of the Flt3/Flk2 Receptor Tyrosine Kinase.

N. Beslu, J. LaRose, N. Casteran, D. Birnbaum, E. Lecocq, P. Dubreuil, and R. Rottapel (1996)
J. Biol. Chem. 271, 20075-20081
 |  Abstract »  |  Full Text »  |  PDF »

Mouse p170 Is a Novel Phosphatidylinositol 3-Kinase Containing a C2 Domain.

J. V. Virbasius, A. Guilherme, and M. P. Czech (1996)
J. Biol. Chem. 271, 13304-13307
 |  Abstract »  |  Full Text »  |  PDF »

Insulin-mediated Targeting of Phosphatidylinositol 3-Kinase to GLUT4-containing Vesicles.

R. A. Heller-Harrison, M. Morin, A. Guilherme, and M. P. Czech (1996)
J. Biol. Chem. 271, 10200-10204
 |  Abstract »  |  Full Text »  |  PDF »

Localization of Platelet-derived Growth Factor-stimulated Phosphorylation Cascade to Caveolae.

P. Liu, Y. Ying, Y.-G. Ko, and R. G. W. Anderson (1996)
J. Biol. Chem. 271, 10299-10303
 |  Abstract »  |  Full Text »  |  PDF »

The effect of wortmannin on the localisation of lysosomal type I integral membrane glycoproteins suggests a role for phosphoinositide 3-kinase activity in regulating membrane traffic late in the endocytic pathway.

B. Reaves, N. Bright, B. Mullock, and J. Luzio (1996)
J. Cell Sci. 109, 749-762
 |  Abstract »  |  PDF »

Sodium Butyrate Inhibits Platelet-Derived Growth Factor–Induced Proliferation of Vascular Smooth Muscle Cells.

K. Ranganna, T. Joshi, and F. M. Yatsu (1995)
Arterioscler Thromb Vasc Biol 15, 2273-2283
 |  Abstract »  |  Full Text »

Wortmannin, an Inhibitor of Phosphoinositide 3-Kinase, Inhibits Transcytosis in Polarized Epithelial Cells.

S. H. Hansen, A. Olsson, and J. E. Casanova (1995)
J. Biol. Chem. 270, 28425-28432
 |  Abstract »  |  Full Text »  |  PDF »

Phosphoinositide 3-Kinase Binds Constitutively to alpha/beta-Tubulin and Binds to [IMAGE]-Tubulin in Response to Insulin.

R. Kapeller, A. Toker, L. C. Cantley, and C. L. Carpenter (1995)
J. Biol. Chem. 270, 25985-25991
 |  Abstract »  |  Full Text »  |  PDF »

Cytotoxic T Lymphocyte-associated Molecule-4, a High Avidity Receptor for CD80 and CD86, Contains an Intracellular Localization Motif in Its Cytoplasmic Tail.

H. T. Leung, J. Bradshaw, J. S. Cleaveland, and P. S. Linsley (1995)
J. Biol. Chem. 270, 25107-25114
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of Tyrosine 503 in the Erythropoietin Receptor (EpR) Is Essential for Binding the P85 Subunit of Phosphatidylinositol (PI) 3-Kinase and for EpR-associated PI 3-Kinase Activity.

J. E. Damen, R. L. Cutler, H. Jiao, T. Yi, and G. Krystal (1995)
J. Biol. Chem. 270, 23402-23408
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of the Flt-1 Tyrosine Kinase Receptor with the p85 Subunit of Phosphatidylinositol 3-Kinase.

S. A. Cunningham, M. N. Waxham, P. M. Arrate, and T. A. Brock (1995)
J. Biol. Chem. 270, 20254-20257
 |  Abstract »  |  Full Text »  |  PDF »

Specific Association of the beta Isoform of the p85 Subunit of Phosphatidylinositol-3 Kinase with the Proto-oncogene c-cbl.

D. Hartley, H. Meisner, and S. Corvera (1995)
J. Biol. Chem. 270, 18260-18263
 |  Abstract »  |  Full Text »  |  PDF »

Growth Hormone, Interferon-[IMAGE], and Leukemia Inhibitory Factor Promoted Tyrosyl Phosphorylation of Insulin Receptor Substrate-1.

L. S. Argetsinger, G. W. Hsu, M. G. Myers Jr., N. Billestrup, M. F. White, and C. Carter-Su (1995)
J. Biol. Chem. 270, 14685-14692
 |  Abstract »  |  Full Text »  |  PDF »

Superresolution three-dimensional images of fluorescence in cells with minimal light exposure.

W. Carrington, R. Lynch, E. Moore, G Isenberg, K. Fogarty, and F. Fay (1995)
Science 268, 1483-1487
 |  Abstract »  |  PDF »

Ras-dependent induction of cellular responses by constitutively active phosphatidylinositol-3 kinase.

Q Hu, A Klippel, A. Muslin, W. Fantl, and L. Williams (1995)
Science 268, 100-102
 |  Abstract »  |  PDF »

Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor.

R Yao and G. Cooper (1995)
Science 267, 2003-2006
 |  Abstract »  |  PDF »

Insulin Receptor Kinase Activation Releases a Constraint Maintaining the Receptor on Microvilli.

J.-L. Carpentier and D. McClain (1995)
J. Biol. Chem. 270, 5001-5006
 |  Abstract »  |  Full Text »  |  PDF »

The Effects of Wortmannin on Rat Skeletal Muscle.

J.-I Yeh, E. A. Gulve, L. Rameh, and M. J. Birnbaum (1995)
J. Biol. Chem. 270, 2107-2111
 |  Abstract »  |  Full Text »  |  PDF »

Schizosaccharomyces pombe Vps34p, a phosphatidylinositol-specific PI 3-kinase essential for normal cell growth and vacuole morphology.

K Takegawa, D. DeWald, and S. Emr (1995)
J. Cell Sci. 108, 3745-3756
 |  Abstract »  |  PDF »

Inositol Hexakisphosphate Binds to Clathrin Assembly Protein 3 (AP-3/AP180) and Inhibits Clathrin Cage Assembly in Vitro.

F. A. Norris, E. Ungewickell, and P. W. Majerus (1995)
J. Biol. Chem. 270, 214-217
 |  Abstract »  |  Full Text »  |  PDF »

Novel Protein Kinase/Phosphatidylinositol 3-Kinase Complex Essential for Receptor-mediated Protein Sorting to the Vacuole in Yeast.

J.H. Stack, P.K. Herman, D.B. DeWald, E.G. Marcusson, J. Lin Cereghino, B.F. Horazdovsky, and S.D. Emr (1995)
Cold Spring Harb Symp Quant Biol 60, 157-170
 |  Abstract »  |  PDF »

Molecular Mechanisms in Synaptic Vesicle Endocytosis.

R. Baurfend, C. David, T. Galli, P.S. McPherson, K. Takei, and P. De Camilli (1995)
Cold Spring Harb Symp Quant Biol 60, 397-404
 |  Abstract »  |  PDF »

The Recruitment of Raf-1 to Membranes Is Mediated by Direct Interaction with Phosphatidic Acid and Is Independent of Association with Ras.

M. A. Rizzo, K. Shome, S. C. Watkins, and G. Romero (2000)
J. Biol. Chem. 275, 23911-23918
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Agonist-dependent Recruitment of Phosphoinositide 3-Kinase to the Membrane by beta -Adrenergic Receptor Kinase 1. A ROLE IN RECEPTOR SEQUESTRATION.

S. V. Naga Prasad, L. S. Barak, A. Rapacciuolo, M. G. Caron, and H. A. Rockman (2001)
J. Biol. Chem. 276, 18953-18959
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