Science 17 December 1993: Vol. 262. no. 5141, pp. 1844 - 1849 DOI: 10.1126/science.8266072

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Articles

Mcm10 Mediates the Interaction Between DNA Replication and Silencing Machineries.

I. Liachko and B. K. Tye (2009)
Genetics 181, 379-391
 |  Abstract »  |  Full Text »  |  PDF »

Positive roles of SAS2 in DNA replication and transcriptional silencing in yeast.

Y. Zou and X. Bi (2008)
Nucleic Acids Res. 36, 5189-5200
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of Chromosome III Replicators Reveals an Unusual Structure for the ARS318 Silencer Origin and a Conserved WTW Sequence within the Origin Recognition Complex Binding Site.

F. Chang, J. F. Theis, J. Miller, C. A. Nieduszynski, C. S. Newlon, and M. Weinreich (2008)
Mol. Cell. Biol. 28, 5071-5081
 |  Abstract »  |  Full Text »  |  PDF »

Differential association of Orc1 and Sir2 proteins to telomeric domains in Plasmodium falciparum.

L. Mancio-Silva, A. P. Rojas-Meza, M. Vargas, A. Scherf, and R. Hernandez-Rivas (2008)
J. Cell Sci. 121, 2046-2053
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of Origin Recognition Complex in Saccharomyces cerevisiae by Use of Degron Mutants.

M. Makise, N. Matsui, F. Yamairi, N. Takahashi, M. Takehara, T. Asano, and T. Mizushima (2008)
J. Biochem. 143, 455-465
 |  Abstract »  |  Full Text »  |  PDF »

Site-specific interaction of the murine pre-replicative complex with origin DNA: assembly and disassembly during cell cycle transit and differentiation.

E. Zellner, T. Herrmann, C. Schulz, and F. Grummt (2007)
Nucleic Acids Res. 35, 6701-6713
 |  Abstract »  |  Full Text »  |  PDF »

Abnormality in Initiation Program of DNA Replication Is Monitored by the Highly Repetitive rRNA Gene Array on Chromosome XII in Budding Yeast.

S. Ide, K. Watanabe, H. Watanabe, K. Shirahige, T. Kobayashi, and H. Maki (2007)
Mol. Cell. Biol. 27, 568-578
 |  Abstract »  |  Full Text »  |  PDF »

Mcm10 Is Required for the Maintenance of Transcriptional Silencing in Saccharomyces cerevisiae.

I. Liachko and B. K. Tye (2005)
Genetics 171, 503-515
 |  Abstract »  |  Full Text »  |  PDF »

Apoptosis in budding yeast caused by defects in initiation of DNA replication.

M. Weinberger, L. Ramachandran, L. Feng, K. Sharma, X. Sun, M. Marchetti, J. A. Huberman, and W. C. Burhans (2005)
J. Cell Sci. 118, 3543-3553
 |  Abstract »  |  Full Text »  |  PDF »

Control of replication initiation and heterochromatin formation in Saccharomyces cerevisiae by a regulator of meiotic gene expression.

H. Irlbacher, J. Franke, T. Manke, M. Vingron, and A. E. Ehrenhofer-Murray (2005)
Genes & Dev. 19, 1811-1822
 |  Abstract »  |  Full Text »  |  PDF »

Structural basis for origin recognition complex 1 protein-silence information regulator 1 protein interaction in epigenetic silencing.

H.-C. Hsu, B. Stillman, and R.-M. Xu (2005)
PNAS 102, 8519-8524
 |  Abstract »  |  Full Text »  |  PDF »

The Highly Conserved tRNAHis Guanylyltransferase Thg1p Interacts with the Origin Recognition Complex and Is Required for the G2/M Phase Transition in the Yeast Saccharomyces cerevisiae.

T. S. Rice, M. Ding, D. S. Pederson, and N. H. Heintz (2005)
Eukaryot. Cell 4, 832-835
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Budding Yeast Replication Origins and Suppression of Lethal DNA Damage Effects on Origin Function by Ectopic Expression of the Co-chaperone Protein Mge1.

P. A. Trabold, M. Weinberger, L. Feng, and W. C. Burhans (2005)
J. Biol. Chem. 280, 12413-12421
 |  Abstract »  |  Full Text »  |  PDF »

Coordination of replication and transcription along a Drosophila chromosome.

D. M. MacAlpine, H. K. Rodriguez, and S. P. Bell (2004)
Genes & Dev. 18, 3094-3105
 |  Abstract »  |  Full Text »  |  PDF »

Dependence of ORC Silencing Function on NatA-Mediated N{alpha} Acetylation in Saccharomyces cerevisiae.

A. Geissenhoner, C. Weise, and A. E. Ehrenhofer-Murray (2004)
Mol. Cell. Biol. 24, 10300-10312
 |  Abstract »  |  Full Text »  |  PDF »

The Origin Recognition Complex Links Replication, Sister Chromatid Cohesion and Transcriptional Silencing in Saccharomyces cerevisiae.

B. Suter, A. Tong, M. Chang, L. Yu, G. W. Brown, C. Boone, and J. Rine (2004)
Genetics 167, 579-591
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of the S-phase cyclin Clb5 with an 'RXL' docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch.

G. M. Wilmes, V. Archambault, R. J. Austin, M. D. Jacobson, S. P. Bell, and F. R. Cross (2004)
Genes & Dev. 18, 981-991
 |  Abstract »  |  Full Text »  |  PDF »

Bloodstream Form-specific Up-regulation of Silent VSG Expression Sites and Procyclin in Trypanosoma brucei after Inhibition of DNA Synthesis or DNA Damage.

K. Sheader, D. te Vruchte, and G. Rudenko (2004)
J. Biol. Chem. 279, 13363-13374
 |  Abstract »  |  Full Text »  |  PDF »

The NAD+-dependent Sir2p histone deacetylase is a negative regulator of chromosomal DNA replication.

D. L. Pappas Jr., R. Frisch, and M. Weinreich (2004)
Genes & Dev. 18, 769-781
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Interaction of an Origin Recognition Complex Subunit and the Polycomb Group Gene MEDEA during Seed Development.

M. A. Collinge, C. Spillane, C. Kohler, J. Gheyselinck, and U. Grossniklaus (2004)
PLANT CELL 16, 1035-1046
 |  Abstract »  |  Full Text »  |  PDF »

Analysis on Origin Recognition Complex containing Orc5p with defective Walker A Motif.

N. Takahashi, Y. Yamaguchi, F. Yamairi, M. Makise, H. Takenaka, T. Tsuchiya, and T. Mizushima (2004)
J. Biol. Chem. 279, 8469-8477
 |  Abstract »  |  Full Text »  |  PDF »

One-Hybrid Screens at the Saccharomyces cerevisiae HMR Locus Identify Novel Transcriptional Silencing Factors.

E. D. Andrulis, D. C. Zappulla, K. Alexieva-Botcheva, C. Evangelista, and R. Sternglanz (2004)
Genetics 166, 631-635
 |  Abstract »  |  Full Text »  |  PDF »

Kinetics of ATP Binding to the Origin Recognition Complex of Saccharomyces cerevisiae.

M. Makise, H. Takenaka, W. Kuwae, N. Takahashi, T. Tsuchiya, and T. Mizushima (2003)
J. Biol. Chem. 278, 46440-46445
 |  Abstract »  |  Full Text »  |  PDF »

The ORC1 Cycle in Human Cells: I. CELL CYCLE-REGULATED OSCILLATION OF HUMAN ORC1.

Y. Tatsumi, S. Ohta, H. Kimura, T. Tsurimoto, and C. Obuse (2003)
J. Biol. Chem. 278, 41528-41534
 |  Abstract »  |  Full Text »  |  PDF »

GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast.

Y. Takayama, Y. Kamimura, M. Okawa, S. Muramatsu, A. Sugino, and H. Araki (2003)
Genes & Dev. 17, 1153-1165
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Uhp1, a Ubiquitinated Histone-like Protein, as a Target/Mediator of Rhp6 in Mating-type Silencing in Fission Yeast.

A. Naresh, S. Saini, and J. Singh (2003)
J. Biol. Chem. 278, 9185-9194
 |  Abstract »  |  Full Text »  |  PDF »

Putative subunits of the maize origin of replication recognition complex ZmORC1-ZmORC5.

X. Witmer, R. Alvarez-Venegas, P. San-Miguel, O. Danilevskaya, and Z. Avramova (2003)
Nucleic Acids Res. 31, 619-628
 |  Abstract »  |  Full Text »  |  PDF »

Cell-cycle control of the establishment of mating-type silencing in S. cerevisiae.

A. Lau, H. Blitzblau, and S. P. Bell (2002)
Genes & Dev. 16, 2935-2945
 |  Abstract »  |  Full Text »  |  PDF »

Two mcm3 Mutations Affect Different Steps in the Initiation of DNA Replication.

M. Lei, I. H. Cheng, L. A. Roberts, M. A. McAlear, and B. K. Tye (2002)
J. Biol. Chem. 277, 30824-30831
 |  Abstract »  |  Full Text »  |  PDF »

Dynamic Localization of an Okazaki Fragment Processing Protein Suggests a Novel Role in Telomere Replication.

W. Choe, M. Budd, O. Imamura, L. Hoopes, and J. L. Campbell (2002)
Mol. Cell. Biol. 22, 4202-4217
 |  Abstract »  |  Full Text »  |  PDF »

Overlapping Roles of the Spindle Assembly and DNA Damage Checkpoints in the Cell-Cycle Response to Altered Chromosomes in Saccharomyces cerevisiae.

P. M. Garber and J. Rine (2002)
Genetics 161, 521-534
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of RAD9-Dependent Damage Checkpoint Control in Arrest of Cell Cycle, Induction of Cell Death, and Chromosome Instability Caused by Defects in Origin Recognition Complex in Saccharomyces cerevisiae.

K. Watanabe, J. Morishita, K. Umezu, K. Shirahige, and H. Maki (2002)
Eukaryot. Cell 1, 200-212
 |  Abstract »  |  Full Text »  |  PDF »

Evidence That the pre-mRNA Splicing Factor Clf1p Plays a Role in DNA Replication in Saccharomyces cerevisiae.

W. Zhu, I. R. Rainville, M. Ding, M. Bolus, N. H. Heintz, and D. S. Pederson (2002)
Genetics 160, 1319-1333
 |  Abstract »  |  Full Text »  |  PDF »

The origin recognition complex: from simple origins to complex functions.

S. P. Bell (2002)
Genes & Dev. 16, 659-672
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Novel Immediate-Early Protein IE19 of Human Cytomegalovirus Activates the Origin Recognition Complex I Promoter in a Cooperative Manner with IE72.

M. Shirakata, M. Terauchi, M. Ablikim, K.-I. Imadome, K. Hirai, T. Aso, and Y. Yamanashi (2002)
J. Virol. 76, 3158-3167
 |  Abstract »  |  Full Text »  |  PDF »

Chromosome Dynamics in the Yeast Interphase Nucleus.

P. Heun, T. Laroche, K. Shimada, P. Furrer, and S. M. Gasser (2001)
Science 294, 2181-2186
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Interactions in Sir Protein Recruitment by Rap1p at Silencers and Telomeres in Yeast.

P. Moretti and D. Shore (2001)
Mol. Cell. Biol. 21, 8082-8094
 |  Abstract »  |  Full Text »  |  PDF »

The Schizosaccharomyces pombe origin recognition complex interacts with multiple AT-rich regions of the replication origin DNA by means of the AT-hook domains of the spOrc4 protein.

J.-K. Lee, K.-Y. Moon, Y. Jiang, and J. Hurwitz (2001)
PNAS 98, 13589-13594
 |  Abstract »  |  Full Text »  |  PDF »

Roles for Internal and Flanking Sequences in Regulating the Activity of Mating-Type-Silencer-Associated Replication Origins in Saccharomyces cerevisiae.

K. Sharma, M. Weinberger, and J. A. Huberman (2001)
Genetics 159, 35-45
 |  Abstract »  |  Full Text »  |  PDF »

DNA Replication Forks Pause at Silent Origins near the HML Locus in Budding Yeast.

Y. Wang, M. Vujcic, and D. Kowalski (2001)
Mol. Cell. Biol. 21, 4938-4948
 |  Abstract »  |  Full Text »  |  PDF »

Drosophila Heterochromatin Protein 1 (HP1)/Origin Recognition Complex (ORC) Protein Is Associated with HP1 and ORC and Functions in Heterochromatin-induced Silencing.

M. M. Shareef, C. King, M. Damaj, R. Badagu, D. W. Huang, and R. Kellum (2001)
Mol. Biol. Cell 12, 1671-1685
 |  Abstract »  |  Full Text »  |  PDF »

The Saccharomyces cerevisiae MUM2 Gene Interacts With the DNA Replication Machinery and Is Required for Meiotic Levels of Double Strand Breaks.

L. Davis, M. Barbera, A. McDonnell, K. McIntyre, R. Sternglanz, Q.-w. Jin, J. Loidl, and J. Engebrecht (2001)
Genetics 157, 1179-1189
 |  Abstract »  |  Full Text »

DNA replication licensing and human cell proliferation.

K. Stoeber, T. D. Tlsty, L. Happerfield, G. A. Thomas, S. Romanov, L. Bobrow, E. D. Williams, and G. H. Williams (2001)
J. Cell Sci. 114, 2027-2041
 |  Abstract »  |  Full Text »  |  PDF »

Chromosomal Addresses of the Cohesin Component Mcd1p.

S. Laloraya, V. Guacci, and D. Koshland (2000)
J. Cell Biol. 151, 1047-1056
 |  Abstract »  |  Full Text »  |  PDF »

Localisation of the DmCdc45 DNA replication factor in the mitotic cycle and during chorion gene amplification.

D. Loebel, H. Huikeshoven, and S. Cotterill (2000)
Nucleic Acids Res. 28, 3897-3903
 |  Abstract »  |  Full Text »  |  PDF »

Identification and Characterization of SA/Scc3p Subunits in the Xenopus and Human Cohesin Complexes.

A. Losada, T. Yokochi, R. Kobayashi, and T. Hirano (2000)
J. Cell Biol. 150, 405-416
 |  Abstract »  |  Full Text »  |  PDF »

Acetylation of Histones and Transcription-Related Factors.

D. E. Sterner and S. L. Berger (2000)
Microbiol. Mol. Biol. Rev. 64, 435-459
 |  Abstract »  |  Full Text »  |  PDF »

Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins.

L. Homesley, M. Lei, Y. Kawasaki, S. Sawyer, T. Christensen, and B. K. Tye (2000)
Genes & Dev. 14, 913-926
 |  Abstract »  |  Full Text »

Association of Human Origin Recognition Complex 1 with Chromatin DNA and Nuclease-resistant Nuclear Structures.

Y. Tatsumi, T. Tsurimoto, K. Shirahige, H. Yoshikawa, and C. Obuse (2000)
J. Biol. Chem. 275, 5904-5910
 |  Abstract »  |  Full Text »  |  PDF »

Yeast heterochromatin is a dynamic structure that requires silencers continuously.

T.-H. Cheng and M. R. Gartenberg (2000)
Genes & Dev. 14, 452-463
 |  Abstract »  |  Full Text »

Interaction of Xenopus Cdc2{middle dot}Cyclin A1 with the Origin Recognition Complex.

P. Romanowski, J. Marr, M. A. Madine, A. Rowles, J. J. Blow, J. Gautier, and R. A. Laskey (2000)
J. Biol. Chem. 275, 4239-4243
 |  Abstract »  |  Full Text »  |  PDF »

Context-Dependent Modulation of Replication Activity of Saccharomyces cerevisiae Autonomously Replicating Sequences by Transcription Factors.

H. Kohzaki, Y. Ito, and Y. Murakami (1999)
Mol. Cell. Biol. 19, 7428-7435
 |  Abstract »  |  Full Text »  |  PDF »

Identification and reconstitution of the origin recognition complex from Schizosaccharomyces pombe.

K.-Y. Moon, D. Kong, J.-K. Lee, S. Raychaudhuri, and J. Hurwitz (1999)
PNAS 96, 12367-12372
 |  Abstract »  |  Full Text »  |  PDF »

Clustered Adenine/Thymine Stretches Are Essential for Function of a Fission Yeast Replication Origin.

Y. Okuno, H. Satoh, M. Sekiguchi, and H. Masukata (1999)
Mol. Cell. Biol. 19, 6699-6709
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation Controls Timing of Cdc6p Destruction: A Biochemical Analysis.

S. Elsasser, Y. Chi, P. Yang, and J. L. Campbell (1999)
Mol. Biol. Cell 10, 3263-3277
 |  Abstract »  |  Full Text »

Activation of Silent Replication Origins at Autonomously Replicating Sequence Elements near the HML Locus in Budding Yeast.

M. Vujcic, C. A. Miller, and D. Kowalski (1999)
Mol. Cell. Biol. 19, 6098-6109
 |  Abstract »  |  Full Text »  |  PDF »

Histone Acetyltransferase HBO1 Interacts with the ORC1 Subunit of the Human Initiator Protein.

M. Iizuka and B. Stillman (1999)
J. Biol. Chem. 274, 23027-23034
 |  Abstract »  |  Full Text »  |  PDF »

Differential assembly of Cdc45p and DNA polymerases at early and late origins of DNA replication.

O. M. Aparicio, A. M. Stout, and S. P. Bell (1999)
PNAS 96, 9130-9135
 |  Abstract »  |  Full Text »  |  PDF »

The fission yeast homologue of Orc4p binds to replication origin DNA via multiple AT-hooks.

R.-Y. Chuang and T. J. Kelly (1999)
PNAS 96, 2656-2661
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin B-Cdk1 Kinase Stimulates ORC- and Cdc6-Independent Steps of Semiconservative Plasmid Replication in Yeast Nuclear Extracts.

B. P. Duncker, P. Pasero, D. Braguglia, P. Heun, M. Weinreich, and S. M. Gasser (1999)
Mol. Cell. Biol. 19, 1226-1241
 |  Abstract »  |  Full Text »  |  PDF »

AAA+: A Class of Chaperone-Like ATPases Associated with the Assembly, Operation, and Disassembly of Protein Complexes.

A. F. Neuwald, L. Aravind, J. L. Spouge, and E. V. Koonin (1999)
Genome Res. 9, 27-43
 |  Abstract »  |  Full Text »

A Region of the Sir1 Protein Dedicated to Recognition of a Silencer and Required for Interaction with the Orc1 Protein in Saccharomyces cerevisiae.

K. A. Gardner, J. Rine, and C. A. Fox (1999)
Genetics 151, 31-44
 |  Abstract »  |  Full Text »

The Orc4p and Orc5p Subunits of the Xenopus and Human Origin Recognition Complex Are Related to Orc1p and Cdc6p.

T. Tugal, X. H. Zou-Yang, K. Gavin, D. Pappin, B. Canas, R. Kobayashi, T. Hunt, and B. Stillman (1998)
J. Biol. Chem. 273, 32421-32429
 |  Abstract »  |  Full Text »  |  PDF »

ORC5L, a New Member of the Human Origin Recognition Complex, Is Deleted in Uterine Leiomyomas and Malignant Myeloid Diseases.

D. G. Quintana, K. C. Thome, Z.-h. Hou, A. H. Ligon, C. C. Morton, and A. Dutta (1998)
J. Biol. Chem. 273, 27137-27145
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Function of the DNA Repair Gene rhp6 in Mating-Type Silencing by Chromatin Remodeling in Fission Yeast.

J. Singh, V. Goel, and A. J. S. Klar (1998)
Mol. Cell. Biol. 18, 5511-5522
 |  Abstract »  |  Full Text »

The Human Homolog of Saccharomyces cerevisiae CDC45.

P. Saha, K. C. Thome, R. Yamaguchi, Z.-h. Hou, S. Weremowicz, and A. Dutta (1998)
J. Biol. Chem. 273, 18205-18209
 |  Abstract »  |  Full Text »  |  PDF »

Human CDC6/Cdc18 Associates with Orc1 and Cyclin-cdk and Is Selectively Eliminated from the Nucleus at the Onset of S Phase.

P. Saha, J. Chen, K. C. Thome, S. J. Lawlis, Z.-h. Hou, M. Hendricks, J. D. Parvin, and A. Dutta (1998)
Mol. Cell. Biol. 18, 2758-2767
 |  Abstract »  |  Full Text »

Roles for ORC in M Phase and S Phase.

A. Dillin and J. Rine (1998)
Science 279, 1733-1737
 |  Abstract »  |  Full Text »

The Cdc7 protein kinase is required for origin firing during S phase.

K. Bousset and J. F.X. Diffley (1998)
Genes & Dev. 12, 480-490
 |  Abstract »  |  Full Text »

Chromatin assembly factor I contributes to the maintenance, but not the re-establishment, of silencing at the yeast silent mating loci.

S. Enomoto and J. Berman (1998)
Genes & Dev. 12, 219-232
 |  Abstract »  |  Full Text »

Discrete Start Sites for DNA Synthesis in the Yeast ARS1 Origin.

A. Bielinsky and S. A. Gerbi (1998)
Science 279, 95-98
 |  Abstract »  |  Full Text »

Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants.

C. Liang and B. Stillman (1997)
Genes & Dev. 11, 3375-3386
 |  Abstract »  |  Full Text »  |  PDF »

Schizosaccharomyces pombe cdc20+ encodes DNA polymerase varepsilon  and is required for chromosomal replication but not for the S phase checkpoint.

G. D'Urso and P. Nurse (1997)
PNAS 94, 12491-12496
 |  Abstract »  |  Full Text »  |  PDF »

CDC45 is required in conjunction with CDC7/DBF4 to trigger the initiation of DNA replication.

J. C. Owens, C. S. Detweiler, and J. J. Li (1997)
PNAS 94, 12521-12526
 |  Abstract »  |  Full Text »  |  PDF »

Identification of HsORC4, a Member of the Human Origin of Replication Recognition Complex.

D. G. Quintana, Z.-h. Hou, K. C. Thome, M. Hendricks, P. Saha, and A. Dutta (1997)
J. Biol. Chem. 272, 28247-28251
 |  Abstract »  |  Full Text »  |  PDF »

The ARS309 chromosomal replicator of Saccharomyces cerevisiae depends on an exceptional ARS consensus sequence.

J. F. Theis and C. S. Newlon (1997)
PNAS 94, 10786-10791
 |  Abstract »  |  Full Text »  |  PDF »

A DNA Helicase Activity Is Associated with an MCM4, -6, and -7 Protein Complex.

Y. Ishimi (1997)
J. Biol. Chem. 272, 24508-24513
 |  Abstract »  |  Full Text »  |  PDF »

Changes of telomere length cause reciprocal changes in the lifespan of mother cells in Saccharomyces cerevisiae.

N. R. Austriaco Jr. and L. P. Guarente (1997)
PNAS 94, 9768-9772
 |  Abstract »  |  Full Text »  |  PDF »

ORC-dependent and origin-specific initiation of DNA replication at defined foci in isolated yeast nuclei..

P Pasero, D Braguglia, and S M Gasser (1997)
Genes & Dev. 11, 1504-1518
 |  Abstract »  |  PDF »

The k43 gene, required for chorion gene amplification and diploid cell chromosome replication, encodes the Drosophila homolog of yeast origin recognition complex subunit 2.

G. Landis, R. Kelley, A. C. Spradling, and J. Tower (1997)
PNAS 94, 3888-3892
 |  Abstract »  |  Full Text »  |  PDF »

A Role for Cdk2 Kinase in Negatively Regulating DNA Replication during S Phase of the Cell Cycle.

X. H. Hua, H. Yan, and J. Newport (1997)
J. Cell Biol. 137, 183-192
 |  Abstract »  |  Full Text »  |  PDF »

Ultraviolet radiation sensitivity and reduction of telomeric silencing in Saccharomyces cerevisiae cells lacking chromatin assembly factor-I..

P D Kaufman, R Kobayashi, and B Stillman (1997)
Genes & Dev. 11, 345-357
 |  Abstract »  |  PDF »

Cdc6p establishes and maintains a state of replication competence during G1 phase.

C. Detweiler and J. Li (1997)
J. Cell Sci. 110, 753-763
 |  Abstract »  |  PDF »

Once and only once upon a time: specifying and regulating origins of DNA replication in eukaryotic cells..

J F Diffley (1996)
Genes & Dev. 10, 2819-2830
 |  PDF »

The ORC1 homolog orp1 in fission yeast plays a key role in regulating onset of S phase..

B Grallert and P Nurse (1996)
Genes & Dev. 10, 2644-2654
 |  Abstract »  |  PDF »

Binding of Human Minichromosome Maintenance Proteins with Histone H3.

Y. Ishimi, S. Ichinose, A. Omori, K. Sato, and H. Kimura (1996)
J. Biol. Chem. 271, 24115-24122
 |  Abstract »  |  Full Text »  |  PDF »

Purification, Gene Cloning, and Reconstitution of the Heterotrimeric Single-stranded DNA-binding Protein from Schizosaccharomyces pombe.

M. Ishiai, J. P. Sanchez, A. A. Amin, Y. Murakami, and J. Hurwitz (1996)
J. Biol. Chem. 271, 20868-20878
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression..

L Maillet, C Boscheron, M Gotta, S Marcand, E Gilson, and S M Gasser (1996)
Genes & Dev. 10, 1796-1811
 |  Abstract »  |  PDF »

Silencing of genes at nontelomeric sites in yeast is controlled by sequestration of silencing factors at telomeres by Rap 1 protein..

S Marcand, S W Buck, P Moretti, E Gilson, and D Shore (1996)
Genes & Dev. 10, 1297-1309
 |  Abstract »  |  PDF »

Silencers are required for inheritance of the repressed state in yeast..

S G Holmes and J R Broach (1996)
Genes & Dev. 10, 1021-1032
 |  Abstract »  |  PDF »

The Saccharomyces retrotransposon Ty5 integrates preferentially into regions of silent chromatin at the telomeres and mating loci..

S Zou, N Ke, J M Kim, and D F Voytas (1996)
Genes & Dev. 10, 634-645
 |  Abstract »  |  PDF »

Conserved Initiator Proteins in Eukaryotes.

K. A. Gavin, M. Hidaka, and B. Stillman (1995)
Science 270, 1667-1671
 |  Abstract »  |  PDF »

Separation of Origin Recognition Complex Functions by Cross-Species Complementation.

A. E. Ehrenhofer-Murray, M. Gossen, D. T. S. Pak, M. R. Botchan, and J. Rine (1995)
Science 270, 1671-1674
 |  Abstract »  |  PDF »

A Drosophila Homolog of the Yeast Origin Recognition Complex.

M. Gossen, D. T. S. Pak, S. K. Hansen, J. K. Acharya, and M. R. Botchan (1995)
Science 270, 1674-1677
 |  Abstract »  |  PDF »

The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability..

C B Brachmann, J M Sherman, S E Devine, E E Cameron, L Pillus, and J D Boeke (1995)
Genes & Dev. 9, 2888-2902
 |  Abstract »  |  PDF »

The origin recognition complex has essential functions in transcriptional silencing and chromosomal replication..

C A Fox, S Loo, A Dillin, and J Rine (1995)
Genes & Dev. 9, 911-924
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Action of a RAP1 carboxy-terminal silencing domain reveals an underlying competition between HMR and telomeres in yeast..

S W Buck and D Shore (1995)
Genes & Dev. 9, 370-384
 |  Abstract »  |  PDF »

Mutations derepressing silent centromeric domains in fission yeast disrupt chromosome segregation..

R C Allshire, E R Nimmo, K Ekwall, J P Javerzat, and G Cranston (1995)
Genes & Dev. 9, 218-233
 |  Abstract »  |  PDF »

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