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Science 10 December 1993:
Vol. 262. no. 5140, pp. 1669 - 1676
DOI: 10.1126/science.262.5140.1669
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Articles

Lipid Tubules: A Paradigm for Molecularly Engineered Structures

Joel M. Schnur 1

1 Center for Bio/Molecular Science and Engineering, Code 6900, Naval Research Laboratory, Washington, DC 20375-5348

The use of molecular self-assembly to fabricate microstructures suitable for advanced material development is described. Templating techniques that transform biomolecular self-assemblies into rugged and stable nano- and microstructures are described. By using a lipid-based microcylinder (tubule) as a paradigm, the path followed from research and development to emerging technological applications is detailed. This process includes modification of the lipid molecular structure, the formation and subsequent characterization of cylindrical microstructures, the use of these structures as templates for metallization, and the characterization and assessment of these hollow metal microcylinders for several potential applications.


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