Science 12 November 1993: Vol. 262. no. 5136, pp. 1059 - 1061 DOI: 10.1126/science.8235625

Prev | Table of Contents | Next

Articles

Proteolytic Activation of the Cytotoxic Phenotype during Human NK Cell Development.

(2009)
J. Immunol. 183, 803-813

Optic Neuritis in Different Strains of Mice by a Recombinant HSV-1 Expressing Murine Interleukin-2.

M. Zandian, R. Belisle, K. R. Mott, S. Nusinowitz, F. M. Hofman, and H. Ghiasi (2009)
Invest. Ophthalmol. Vis. Sci. 50, 3275-3282
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-10/Interleukin-5 Responses at Birth Predict Risk for Respiratory Infections in Children with Atopic Family History.

G. Zhang, J. Rowe, M. Kusel, A. Bosco, K. McKenna, N. de Klerk, P. D. Sly, and P. G. Holt (2009)
Am. J. Respir. Crit. Care Med. 179, 205-211
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: CD4+ T Cell-Derived IL-2 Is Essential for Help-Dependent Primary CD8+ T Cell Responses.

E. B. Wilson and A. M. Livingstone (2008)
J. Immunol. 181, 7445-7448
 |  Abstract »  |  Full Text »  |  PDF »

IL-21 promotes T lymphocyte survival by activating the phosphatidylinositol-3 kinase signaling cascade.

V. Ostiguy, E.-L. Allard, M. Marquis, J. Leignadier, and N. Labrecque (2007)
J. Leukoc. Biol. 82, 645-656
 |  Abstract »  |  Full Text »  |  PDF »

IL-2 Regulates Expansion of CD4+ T Cell Populations by Affecting Cell Death: Insights from Modeling CFSE Data.

V. V. Ganusov, D. Milutinovic, and R. J. De Boer (2007)
J. Immunol. 179, 950-957
 |  Abstract »  |  Full Text »  |  PDF »

Parallel Expansion of Human Virus-Specific FoxP3- Effector Memory and De Novo-Generated FoxP3+ Regulatory CD8+ T Cells upon Antigen Recognition In Vitro.

E. Billerbeck, H. E. Blum, and R. Thimme (2007)
J. Immunol. 179, 1039-1048
 |  Abstract »  |  Full Text »  |  PDF »

The IL-15/IL-15R{alpha} on cell surfaces enables sustained IL-15 activity and contributes to the long survival of CD8 memory T cells.

N. Sato, H. J. Patel, T. A. Waldmann, and Y. Tagaya (2007)
PNAS 104, 588-593
 |  Abstract »  |  Full Text »  |  PDF »

Selective Availability of IL-2 Is a Major Determinant Controlling the Production of CD4+CD25+Foxp3+ T Regulatory Cells.

A. Yu and T. R. Malek (2006)
J. Immunol. 177, 5115-5121
 |  Abstract »  |  Full Text »  |  PDF »

p300/Cyclic AMP-Responsive Element Binding-Binding Protein Mediates Transcriptional Coactivation by the CD28 T Cell Costimulatory Receptor.

S. L. Nandiwada, W. Li, R. Zhang, and D. L. Mueller (2006)
J. Immunol. 177, 401-413
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-2-Dependent Mechanisms of Tolerance and Immunity In Vivo.

P. A. Antony, C. M. Paulos, M. Ahmadzadeh, A. Akpinarli, D. C. Palmer, N. Sato, A. Kaiser, C. Heinrichs, C. A. Klebanoff, Y. Tagaya, et al. (2006)
J. Immunol. 176, 5255-5266
 |  Abstract »  |  Full Text »  |  PDF »

Direct Stimulation of T Cells by Type I IFN Enhances the CD8+ T Cell Response during Cross-Priming..

A. Le Bon, V. Durand, E. Kamphuis, C. Thompson, S. Bulfone-Paus, C. Rossmann, U. Kalinke, and D. F. Tough (2006)
J. Immunol. 176, 4682-4689
 |  Abstract »  |  Full Text »  |  PDF »

Regulatory CD56bright natural killer cells mediate immunomodulatory effects of IL-2R{alpha}-targeted therapy (daclizumab) in multiple sclerosis.

B. Bielekova, M. Catalfamo, S. Reichert-Scrivner, A. Packer, M. Cerna, T. A. Waldmann, H. McFarland, P. A. Henkart, and R. Martin (2006)
PNAS 103, 5941-5946
 |  Abstract »  |  Full Text »  |  PDF »

Cytokines in Atherosclerosis: Pathogenic and Regulatory Pathways.

A. Tedgui and Z. Mallat (2006)
Physiol Rev 86, 515-581
 |  Abstract »  |  Full Text »  |  PDF »

Quantitative assessment concerning the contribution of IL-2R{beta} for superantigen-mediated T cell responses in vivo.

H. Jin, D. Gong, D. Adeegbe, A. L. Bayer, C. Rolle, A. Yu, and T. R. Malek (2006)
Int. Immunol. 18, 565-572
 |  Abstract »  |  Full Text »  |  PDF »

The Structure of the Interleukin-15{alpha} Receptor and Its Implications for Ligand Binding.

I. Lorenzen, A. J. Dingley, Y. Jacques, and J. Grotzinger (2006)
J. Biol. Chem. 281, 6642-6647
 |  Abstract »  |  Full Text »  |  PDF »

IL-2 Regulates Perforin and Granzyme Gene Expression in CD8+ T Cells Independently of Its Effects on Survival and Proliferation.

M. L. Janas, P. Groves, N. Kienzle, and A. Kelso (2005)
J. Immunol. 175, 8003-8010
 |  Abstract »  |  Full Text »  |  PDF »

Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen.

B. Knoechel, J. Lohr, E. Kahn, J. A. Bluestone, and A. K. Abbas (2005)
J. Exp. Med. 202, 1375-1386
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase C {theta} Is Not Essential for T-Cell-Mediated Clearance of Murine Gammaherpesvirus 68.

F. Giannoni, A. B. Lyon, M. D. Wareing, P. B. Dias, and S. R. Sarawar (2005)
J. Virol. 79, 6808-6813
 |  Abstract »  |  Full Text »  |  PDF »

Inaugural Article: BCL6b mediates the enhanced magnitude of the secondary response of memory CD8+ T lymphocytes.

P. M. Manders, P. J. Hunter, A. I. Telaranta, J. M. Carr, J. L. Marshall, M. Carrasco, Y. Murakami, M. J. Palmowski, V. Cerundolo, S. M. Kaech, et al. (2005)
PNAS 102, 7418-7425
 |  Abstract »  |  Full Text »  |  PDF »

CD8+ T Cell Immunity Against a Tumor/Self-Antigen Is Augmented by CD4+ T Helper Cells and Hindered by Naturally Occurring T Regulatory Cells.

P. A. Antony, C. A. Piccirillo, A. Akpinarli, S. E. Finkelstein, P. J. Speiss, D. R. Surman, D. C. Palmer, C.-C. Chan, C. A. Klebanoff, W. W. Overwijk, et al. (2005)
J. Immunol. 174, 2591-2601
 |  Abstract »  |  Full Text »  |  PDF »

Interleukins 2 and 15 Regulate Ets1 Expression via ERK1/2 and MNK1 in Human Natural Killer Cells.

E. M. Grund, D. D. Spyropoulos, D. K. Watson, and R. C. Muise-Helmericks (2005)
J. Biol. Chem. 280, 4772-4778
 |  Abstract »  |  Full Text »  |  PDF »

Roles for Common Cytokine Receptor {gamma}-Chain-Dependent Cytokines in the Generation, Differentiation, and Maturation of NK Cell Precursors and Peripheral NK Cells in Vivo.

C. A. J. Vosshenrich, T. Ranson, S. I. Samson, E. Corcuff, F. Colucci, E. E. Rosmaraki, and J. P. Di Santo (2005)
J. Immunol. 174, 1213-1221
 |  Abstract »  |  Full Text »  |  PDF »

Enhancement of the host immune responses in cutaneous T-cell lymphoma by CpG oligodeoxynucleotides and IL-15.

M. Wysocka, B. M. Benoit, S. Newton, L. Azzoni, L. J. Montaner, and A. H. Rook (2004)
Blood 104, 4142-4149
 |  Abstract »  |  Full Text »  |  PDF »

IL-2 Induces a Competitive Survival Advantage in T Lymphocytes.

H. Dooms, E. Kahn, B. Knoechel, and A. K. Abbas (2004)
J. Immunol. 172, 5973-5979
 |  Abstract »  |  Full Text »  |  PDF »

IL-2, Regulatory T Cells, and Tolerance.

B. H. Nelson (2004)
J. Immunol. 172, 3983-3988
 |  Abstract »  |  Full Text »  |  PDF »

Turnover and Proliferation of NK Cells in Steady State and Lymphopenic Conditions.

A. M. Jamieson, P. Isnard, J. R. Dorfman, M. C. Coles, and D. H. Raulet (2004)
J. Immunol. 172, 864-870
 |  Abstract »  |  Full Text »  |  PDF »

IL-2 Is Not Required for the Initiation of CD8 T Cell Cycling but Sustains Expansion.

W. N. D'Souza and L. Lefrancois (2003)
J. Immunol. 171, 5727-5735
 |  Abstract »  |  Full Text »  |  PDF »

Distinct pathways involving the FK506-binding proteins 12 and 12.6 underlie IL-2-versus IL-15-mediated proliferation of T cells.

S. Dubois, W. Shou, L. S. Haneline, S. Fleischer, T. A. Waldmann, and J. R. Muller (2003)
PNAS 100, 14169-14174
 |  Abstract »  |  Full Text »  |  PDF »

Cytokine requirements for the growth and development of mouse NK cells in vitro.

J. A. Toomey, F. Gays, D. Foster, and C. G. Brooks (2003)
J. Leukoc. Biol. 74, 233-242
 |  Abstract »  |  Full Text »  |  PDF »

IL-15-Mediated Induction of LFA-1 Is a Late Step Required for Cytotoxic Differentiation of Human NK Cells from CD34+Lin- Bone Marrow Cells.

I. Barao, D. Hudig, and J. L. Ascensao (2003)
J. Immunol. 171, 683-690
 |  Abstract »  |  Full Text »  |  PDF »

Oncolytic Vesicular Stomatitis Virus for Treatment of Orthotopic Hepatocellular Carcinoma in Immune-competent Rats.

O. Ebert, K. Shinozaki, T.-G. Huang, M. J. Savontaus, A. Garcia-Sastre, and S. L. C. Woo (2003)
Cancer Res. 63, 3605-3611
 |  Abstract »  |  Full Text »  |  PDF »

Characterization and Analysis of the Proximal Janus Kinase 3 Promoter.

M. Aringer, S. R. Hofmann, D. M. Frucht, M. Chen, M. Centola, A. Morinobu, R. Visconti, D. L. Kastner, J. S. Smolen, and J. J. O'Shea (2003)
J. Immunol. 170, 6057-6064
 |  Abstract »  |  Full Text »  |  PDF »

Comparison of Adjuvant Efficacy of Herpes Simplex Virus Type 1 Recombinant Viruses Expressing TH1 and TH2 Cytokine Genes.

Y. Osorio and H. Ghiasi (2003)
J. Virol. 77, 5774-5783
 |  Abstract »  |  Full Text »  |  PDF »

Stochastic Model of T Cell Proliferation: A Calculus Revealing IL-2 Regulation of Precursor Frequencies, Cell Cycle Time, and Survival.

E. K. Deenick, A. V. Gett, and P. D. Hodgkin (2003)
J. Immunol. 170, 4963-4972
 |  Abstract »  |  Full Text »  |  PDF »

Efficient Induction of Primary and Secondary T Cell-Dependent Immune Responses In Vivo in the Absence of Functional IL-2 and IL-15 Receptors.

A. Yu, J. Zhou, N. Marten, C. C. Bergmann, M. Mammolenti, R. B. Levy, and T. R. Malek (2003)
J. Immunol. 170, 236-242
 |  Abstract »  |  Full Text »  |  PDF »

In vivo evidence for a dependence on interleukin 15 for survival of natural killer cells.

M. A. Cooper, J. E. Bush, T. A. Fehniger, J. B. VanDeusen, R. E. Waite, Y. Liu, H. L. Aguila, and M. A. Caligiuri (2002)
Blood 100, 3633-3638
 |  Abstract »  |  Full Text »  |  PDF »

Relationships between early B- and NK-lineage lymphocyte precursors in bone marrow.

T. Kouro, V. Kumar, and P. W. Kincade (2002)
Blood 100, 3672-3680
 |  Abstract »  |  Full Text »  |  PDF »

Enforced Expression of Bcl-2 Restores the Number of NK Cells, But Does Not Rescue the Impaired Development of NKT Cells or Intraepithelial Lymphocytes, in IL-2/IL-15 Receptor {beta}-Chain-Deficient Mice.

M. Minagawa, H. Watanabe, C. Miyaji, K. Tomiyama, H. Shimura, A. Ito, M. Ito, J. Domen, I. L. Weissman, and K. Kawai (2002)
J. Immunol. 169, 4153-4160
 |  Abstract »  |  Full Text »  |  PDF »

Pentoxifylline Functions As an Adjuvant In Vivo to Enhance T Cell Immune Responses by Inhibiting Activation-Induced Death.

R. Suresh, M. Vig, S. Bhatia, E. P. B. Goodspeed, B. John, U. Kandpal, S. Srivastava, A. George, R. Sen, V. Bal, et al. (2002)
J. Immunol. 169, 4262-4272
 |  Abstract »  |  Full Text »  |  PDF »

Transgenic overexpression of human IL-17E results in eosinophilia, B-lymphocyte hyperplasia, and altered antibody production.

M. R. Kim, R. Manoukian, R. Yeh, S. M. Silbiger, D. M. Danilenko, S. Scully, J. Sun, M. L. DeRose, M. Stolina, D. Chang, et al. (2002)
Blood 100, 2330-2340
 |  Abstract »  |  Full Text »  |  PDF »

Susceptibility of Interleukin-2-Deficient Mice to Toxoplasma gondii Is Associated with a Defect in the Production of Gamma Interferon.

E. N. Villegas, L. A. Lieberman, S. R. Carding, and C. A. Hunter (2002)
Infect. Immun. 70, 4757-4761
 |  Abstract »  |  Full Text »  |  PDF »

CD25+CD4+ T cells contribute to the control of memory CD8+ T cells.

M. Murakami, A. Sakamoto, J. Bender, J. Kappler, and P. Marrack (2002)
PNAS 99, 8832-8837
 |  Abstract »  |  Full Text »  |  PDF »

Essential Role for IL-2 in the Regulation of Antiviral Extralymphoid CD8 T Cell Responses.

W. N. D'Souza, K. S. Schluns, D. Masopust, and L. Lefrancois (2002)
J. Immunol. 168, 5566-5572
 |  Abstract »  |  Full Text »  |  PDF »

Defective expression of the interleukin-2/interleukin-15 receptor {beta} subunit leads to a natural killer cell-deficient form of severe combined immunodeficiency.

K. C. Gilmour, H. Fujii, T. Cranston, E. G. Davies, C. Kinnon, and H. B. Gaspar (2001)
Blood 98, 877-879
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: The Common {{gamma}}-Chain Is an Indispensable Subunit of the IL-21 Receptor Complex.

H. Asao, C. Okuyama, S. Kumaki, N. Ishii, S. Tsuchiya, D. Foster, and K. Sugamura (2001)
J. Immunol. 167, 1-5
 |  Abstract »  |  Full Text »  |  PDF »

Broad Programming by IL-2 Receptor Signaling for Extended Growth to Multiple Cytokines and Functional Maturation of Antigen-Activated T Cells.

T. R. Malek, A. Yu, P. Scibelli, M. G. Lichtenheld, and E. K. Codias (2001)
J. Immunol. 166, 1675-1683
 |  Abstract »  |  Full Text »  |  PDF »

Fatal Leukemia in Interleukin 15 Transgenic Mice Follows Early Expansions in Natural Killer and Memory Phenotype CD8+ T Cells.

T. A. Fehniger, K. Suzuki, A. Ponnappan, J. B. VanDeusen, M. A. Cooper, S. M. Florea, A. G. Freud, M. L. Robinson, J. Durbin, and M. A. Caligiuri (2001)
J. Exp. Med. 193, 219-232
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin 15: biology and relevance to human disease.

T. A. Fehniger and M. A. Caligiuri (2001)
Blood 97, 14-32
 |  Full Text »  |  PDF »

Memory-Type CD8+ T Cells Protect IL-2 Receptor {alpha}-Deficient Mice from Systemic Infection with Herpes Simplex Virus Type 2.

H. Tsunobuchi, H. Nishimura, F. Goshima, T. Daikoku, Y. Nishiyama, and Y. Yoshikai (2000)
J. Immunol. 165, 4552-4560
 |  Abstract »  |  Full Text »  |  PDF »

Defective Thymocyte Development and Perturbed Homeostasis of T cells in STAT-Induced STAT Inhibitor-1/Suppressors of Cytokine Signaling-1 Transgenic Mice.

M. Fujimoto, T. Naka, R. Nakagawa, Y. Kawazoe, Y. Morita, A. Tateishi, K. Okumura, M. Narazaki, and T. Kishimoto (2000)
J. Immunol. 165, 1799-1806
 |  Abstract »  |  Full Text »  |  PDF »

Cytokine Production and Killer Activity of NK/T-NK Cells Derived with IL-2, IL-15, or the Combination of IL-12 and IL-18.

B. R. Lauwerys, N. Garot, J.-C. Renauld, and F. A. Houssiau (2000)
J. Immunol. 165, 1847-1853
 |  Abstract »  |  Full Text »  |  PDF »

The Roles of Prolactin, Growth Hormone, Insulin-Like Growth Factor-I, and Thyroid Hormones in Lymphocyte Development and Function: Insights from Genetic Models of Hormone and Hormone Receptor Deficiency.

K. Dorshkind and N. D. Horseman (2000)
Endocr. Rev. 21, 292-312
 |  Abstract »  |  Full Text »

Regulation of Lymphoid Homeostasis by IL-2 Receptor Signals In Vivo.

D. T. M. Leung, S. Morefield, and D. M. Willerford (2000)
J. Immunol. 164, 3527-3534
 |  Abstract »  |  Full Text »  |  PDF »

Reversible Defects in Natural Killer and Memory CD8 T Cell Lineages in Interleukin 15-deficient Mice.

M. K. Kennedy, M. Glaccum, S. N. Brown, E. A. Butz, J. L. Viney, M. Embers, N. Matsuki, K. Charrier, L. Sedger, C. R. Willis, et al. (2000)
J. Exp. Med. 191, 771-780
 |  Abstract »  |  Full Text »  |  PDF »

The receptor tyrosine kinase c-kit provides a critical signal for survival, expansion, and maturation of mouse natural killer cells.

F. Colucci and J. P. Di Santo (2000)
Blood 95, 984-991
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-15 as an Activator of Natural Killer Cell-Mediated Antiviral Response.

J. Gosselin, A. TomoIu, R. C. Gallo, and L. Flamand (1999)
Blood 94, 4210-4219
 |  Abstract »  |  Full Text »  |  PDF »

Cytokine Deprivation of Naive CD8+ T Cells Promotes Minimal Cell Cycling but Maximal Cytokine Synthesis and Autonomous Proliferation Subsequently: A Mechanism of Self-Regulation.

S. Sad and L. Krishnan (1999)
J. Immunol. 163, 2443-2451
 |  Abstract »  |  Full Text »  |  PDF »

Critical Role of Costimulation in the Activation of Naive Antigen-Specific TCR Transgenic CD8+ T Cells In Vitro.

J.-G. Chai, S. Vendetti, I. Bartok, D. Schoendorf, K. Takacs, J. Elliott, R. Lechler, and J. Dyson (1999)
J. Immunol. 163, 1298-1305
 |  Abstract »  |  Full Text »  |  PDF »

IL-2-deficient mice raised under germfree conditions develop delayed mild focal intestinal inflammation.

M. Schultz, S. L. Tonkonogy, R. K. Sellon, C. Veltkamp, V. L. Godfrey, J. Kwon, W. B. Grenther, E. Balish, I. Horak, and R. B. Sartor (1999)
Am J Physiol Gastrointest Liver Physiol 276, G1461-G1472
 |  Abstract »  |  Full Text »  |  PDF »

The Common Cytokine Receptor gamma  Chain and the Pre-T Cell Receptor Provide Independent but Critically Overlapping Signals in Early alpha /beta T Cell Development.

J. P. Di Santo, I. Aifantis, E. Rosmaraki, C. Garcia, J. Feinberg, H. J. Fehling, A. Fischer, H. von Boehmer, and B. Rocha (1999)
J. Exp. Med. 189, 563-574
 |  Abstract »  |  Full Text »  |  PDF »

Functional Role of Interleukin-4 (IL-4) and IL-7 in the Development of X-Linked Severe Combined Immunodeficiency.

S. Kumaki, N. Ishii, M. Minegishi, S. Tsuchiya, D. Cosman, K. Sugamura, and T. Konno (1999)
Blood 93, 607-612
 |  Abstract »  |  Full Text »  |  PDF »

IL-2 Induces STAT4 Activation in Primary NK Cells and NK Cell Lines, But Not in T Cells.

K. S. Wang, J. Ritz, and D. A. Frank (1999)
J. Immunol. 162, 299-304
 |  Abstract »  |  Full Text »  |  PDF »

Stat5b Is Essential for Natural Killer Cell-mediated Proliferation and Cytolytic Activity.

K. Imada, E. T. Bloom, H. Nakajima, J. A. Horvath-Arcidiacono, G. B. Udy, H. W. Davey, and W. J. Leonard (1998)
J. Exp. Med. 188, 2067-2074
 |  Abstract »  |  Full Text »  |  PDF »

Flt3 Ligand Promotes the Generation of a Distinct CD34+ Human Natural Killer Cell Progenitor That Responds to Interleukin-15.

H. Yu, T. A. Fehniger, P. Fuchshuber, K. S. Thiel, E. Vivier, W. E. Carson, and M. A. Caligiuri (1998)
Blood 92, 3647-3657
 |  Abstract »  |  Full Text »  |  PDF »

Impaired Alloantigen-Mediated T Cell Apoptosis and Failure To Induce Long-Term Allograft Survival in IL-2-Deficient Mice.

Z. Dai, B. T. Konieczny, F. K. Baddoura, and F. G. Lakkis (1998)
J. Immunol. 161, 1659-1663
 |  Abstract »  |  Full Text »  |  PDF »

Differential Effects of Protein Kinase A on Ras Effector Pathways.

M. J. Miller, L. Rioux, G. V. Prendergast, S. Cannon, M. A. White, and J. L. Meinkoth (1998)
Mol. Cell. Biol. 18, 3718-3726
 |  Abstract »  |  Full Text »

CD4+ and CD8+ T Cell Interactions in IFN-{gamma} and IL-4 Responses to Viral Infections: Requirements for IL-2.

H. C. Su, L. P. Cousens, L. D. Fast, M. K. Slifka, R. D. Bungiro, R. Ahmed, and C. A. Biron (1998)
J. Immunol. 160, 5007-5017
 |  Abstract »  |  Full Text »  |  PDF »

Cytokine mRNA expression in intestinal tissue of interleukin-2 deficient mice with bowel inflammation.

I B Autenrieth, N Bucheler, E Bohn, G Heinze, and I Horak (1997)
Gut 41, 793-800
 |  Abstract »  |  Full Text »  |  PDF »

Generation of Lytic Natural Killer 1.1+, Ly-49- Cells from Multipotential Murine Bone Marrow Progenitors in a Stroma-free Culture: Definition of Cytokine Requirements and Developmental Intermediates.

N. S. Williams, T. A. Moore, J. D. Schatzle, I. J. Puzanov, P.V. Sivakumar, A. Zlotnik, M. Bennett, and V. Kumar (1997)
J. Exp. Med. 186, 1609-1614
 |  Abstract »  |  Full Text »  |  PDF »

Cytokine Expression and Tumorigenicity of Large Granular Lymphocytic Leukemia Cells From Mice Transgenic for the tax Gene of Human T-Cell Leukemia Virus Type I.

W. J. Grossman and L. Ratner (1997)
Blood 90, 783-794
 |  Abstract »  |  Full Text »  |  PDF »

Lineage Relationships and Differentiation of Natural Killer (NK) T Cells: Intrathymic Selection and Interleukin (IL)-4 Production in the Absence of NKR-P1 and Ly49 Molecules.

O. Lantz, L. I. Sharara, F. Tilloy, A. Andersson, and J. P. DiSanto (1997)
J. Exp. Med. 185, 1395-1402
 |  Abstract »  |  Full Text »  |  PDF »

The Somatogenic Hormones and Insulin-Like Growth Factor-1: Stimulators of Lymphopoiesis and Immune Function.

R. Clark (1997)
Endocr. Rev. 18, 157-179
 |  Abstract »  |  Full Text »

Abnormal Development of Intestinal Intraepithelial Lymphocytes and Peripheral Natural Killer Cells in Mice Lacking the IL-2 Receptor beta  Chain.

H. Suzuki, G. S. Duncan, H. Takimoto, and T. W. Mak (1997)
J. Exp. Med. 185, 499-506
 |  Abstract »  |  Full Text »  |  PDF »

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression..

F Kontgen, R J Grumont, A Strasser, D Metcalf, R Li, D Tarlinton, and S Gerondakis (1995)
Genes & Dev. 9, 1965-1977
 |  Abstract »  |  PDF »

IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice.

J. Marks-Konczalik, S. Dubois, J. M. Losi, H. Sabzevari, N. Yamada, L. Feigenbaum, T. A. Waldmann, and Y. Tagaya (2000)
PNAS 97, 11445-11450
 |  Abstract »  |  Full Text »  |  PDF »

To Advertise   |   Find Products