Science 5 November 1993: Vol. 262. no. 5135, pp. 909 - 911 DOI: 10.1126/science.7694363

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Articles

Human decidual stromal cells suppress cytokine secretion by allogenic CD4+ T cells via PD-1 ligand interactions.

T. Nagamatsu, D. J. Schust, J. Sugimoto, and B. F. Barrier (2009)
Hum. Reprod. 24, 3160-3171
 |  Abstract »  |  Full Text »  |  PDF »

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity.

N. Stanietsky, H. Simic, J. Arapovic, A. Toporik, O. Levy, A. Novik, Z. Levine, M. Beiman, L. Dassa, H. Achdout, et al. (2009)
PNAS 106, 17858-17863
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Importance of IL-6 and Cooperation between Innate and Adaptive Immune Receptors in Cellular Vaccination with B Lymphocytes.

T. J. Vanden Bush, C. M. Buchta, J. Claudio, and G. A. Bishop (2009)
J. Immunol. 183, 4833-4837
 |  Abstract »  |  Full Text »  |  PDF »

An immunological overview of allergen specific immunotherapy -- subcutaneous and sublingual routes.

C. Ozdemir (2009)
Therapeutic Advances in Respiratory Disease 3, 253-262
 |  Abstract »  |  PDF »

Preclinical biomarkers for a cyclin-dependent kinase inhibitor translate to candidate pharmacodynamic biomarkers in phase I patients.

W. Berkofsky-Fessler, T. Q. Nguyen, P. Delmar, J. Molnos, C. Kanwal, W. DePinto, J. Rosinski, P. McLoughlin, S. Ritland, M. DeMario, et al. (2009)
Mol. Cancer Ther. 8, 2517-2525
 |  Abstract »  |  Full Text »  |  PDF »

Conservation of Structural and Functional Features in a Primordial CD80/86 Molecule from Rainbow Trout (Oncorhynchus mykiss), a Primitive Teleost Fish.

Y.-A. Zhang, J.-i. Hikima, J. Li, S. E. LaPatra, Y.-P. Luo, and J. O. Sunyer (2009)
J. Immunol. 183, 83-96
 |  Abstract »  |  Full Text »  |  PDF »

A Novel B7-2 (CD86) Splice Variant with a Putative Negative Regulatory Role.

E. K. Kapsogeorgou, H. M. Moutsopoulos, and M. N. Manoussakis (2008)
J. Immunol. 180, 3815-3823
 |  Abstract »  |  Full Text »  |  PDF »

B7 Costimulation Molecules Expressed from the Herpes Simplex Virus 2 Genome Rescue Immune Induction in B7-Deficient Mice.

L. G. Thebeau, S. P. Vagvala, Y. M. Wong, and L. A. Morrison (2007)
J. Virol. 81, 12200-12209
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Determinants of Inverse Agonist Activity of Biologicals Targeting CTLA-4.

W. A. Teft and J. Madrenas (2007)
J. Immunol. 179, 3631-3637
 |  Abstract »  |  Full Text »  |  PDF »

The B7 Family and Cancer Therapy: Costimulation and Coinhibition.

X. Zang and J. P. Allison (2007)
Clin. Cancer Res. 13, 5271-5279
 |  Abstract »  |  Full Text »  |  PDF »

CD86 Regulates IgG1 Production via a CD19-Dependent Mechanism.

N. W. Kin and V. M. Sanders (2007)
J. Immunol. 179, 1516-1523
 |  Abstract »  |  Full Text »  |  PDF »

Long-Term Staphylococcal Enterotoxin C1 Exposure Induces Soluble Factor-Mediated Immunosuppression by Bovine CD4+ and CD8+ T Cells.

K. S. Seo, S. U. Lee, Y. H. Park, W. C. Davis, L. K. Fox, and G. A. Bohach (2007)
Infect. Immun. 75, 260-269
 |  Abstract »  |  Full Text »  |  PDF »

Increase in Concentration of Soluble CD86 After Segmental Allergen Challenge in Patients With Allergic Asthma..

X.-D. Liang, H.-Z. Shi, X.-J. Qin, and J.-M. Deng (2006)
Chest 130, 1048-1054
 |  Abstract »  |  Full Text »  |  PDF »

CD86 Stimulation on a B Cell Activates the Phosphatidylinositol 3-Kinase/Akt and Phospholipase C{gamma}2/Protein Kinase C{alpha}beta Signaling Pathways..

N. W. Kin and V. M. Sanders (2006)
J. Immunol. 176, 6727-6735
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of B7.1 Costimulatory Molecule Is Mediated by the IFN Regulatory Factor-7 through the Activation of JNK in Lipopolysaccharide-Stimulated Human Monocytic Cells.

W. Lim, K. Gee, S. Mishra, and A. Kumar (2005)
J. Immunol. 175, 5690-5700
 |  Abstract »  |  Full Text »  |  PDF »

Different cell surface oligomeric states of B7-1 and B7-2: Implications for signaling.

S. Bhatia, M. Edidin, S. C. Almo, and S. G. Nathenson (2005)
PNAS 102, 15569-15574
 |  Abstract »  |  Full Text »  |  PDF »

Anemia, Allogenic Blood Transfusion, and Immunomodulation in the Critically Ill.

M. Raghavan and P. E. Marik (2005)
Chest 127, 295-307
 |  Abstract »  |  Full Text »  |  PDF »

Role of B7 in T Cell Tolerance.

J. Lohr, B. Knoechel, E. C. Kahn, and A. K. Abbas (2004)
J. Immunol. 173, 5028-5035
 |  Abstract »  |  Full Text »  |  PDF »

Soluble CD86 protein in serum samples of patients with asthma.

H-Z Shi, Z-F Xie, J-M Deng, Y-Q Chen, and C-Q Xiao (2004)
Thorax 59, 870-875
 |  Abstract »  |  Full Text »  |  PDF »

CD26 up-regulates expression of CD86 on antigen-presenting cells by means of caveolin-1.

K. Ohnuma, T. Yamochi, M. Uchiyama, K. Nishibashi, N. Yoshikawa, N. Shimizu, S. Iwata, H. Tanaka, N. H. Dang, and C. Morimoto (2004)
PNAS 101, 14186-14191
 |  Abstract »  |  Full Text »  |  PDF »

Eosinophils function as antigen-presenting cells.

H.-Z. Shi (2004)
J. Leukoc. Biol. 76, 520-527
 |  Abstract »  |  Full Text »  |  PDF »

MHC class II-independent and -dependent T cell expansion and B cell hyperactivity in vivo in mice deficient in CD152 (CTLA-4).

W. Stohl, D. Xu, K. S. Kim, C. S. David, and J. P. Allison (2004)
Int. Immunol. 16, 895-904
 |  Abstract »  |  Full Text »  |  PDF »

CD86 and {beta}2-Adrenergic Receptor Signaling Pathways, Respectively, Increase Oct-2 and OCA-B Expression and Binding to the 3'-IgH Enhancer in B Cells.

J. R. Podojil, N. W. Kin, and V. M. Sanders (2004)
J. Biol. Chem. 279, 23394-23404
 |  Abstract »  |  Full Text »  |  PDF »

Cross-regulation of CD86 by CD80 differentially regulates T helper responses from Mycobacterium tuberculosis secretory antigen-activated dendritic cell subsets.

M. Y. Balkhi, V. K. Latchumanan, B. Singh, P. Sharma, and K. Natarajan (2004)
J. Leukoc. Biol. 75, 874-883
 |  Abstract »  |  Full Text »  |  PDF »

CD86 and CD80 Differentially Modulate the Suppressive Function of Human Regulatory T Cells.

Y. Zheng, C. N. Manzotti, M. Liu, F. Burke, K. I. Mead, and D. M. Sansom (2004)
J. Immunol. 172, 2778-2784
 |  Abstract »  |  Full Text »  |  PDF »

CD40/CD40 Homodimers Are Required for CD40-induced Phosphatidylinositol 3-Kinase-dependent Expression of B7.2 by Human B Lymphocytes.

C. Reyes-Moreno, J. Girouard, R. Lapointe, A. Darveau, and W. Mourad (2004)
J. Biol. Chem. 279, 7799-7806
 |  Abstract »  |  Full Text »  |  PDF »

Two-signal requirement for activation and effector function of natural killer cell response to allogeneic tumor cells.

J.-X. Gao, X. Liu, J. Wen, M. A. Caligiuri, I. Stroynowski, P. Zheng, and Y. Liu (2003)
Blood 102, 4456-4463
 |  Abstract »  |  Full Text »  |  PDF »

Costimulatory Molecule Immune Enhancement in a Plasmid Vaccine Model Is Regulated in Part Through the Ig Constant-Like Domain of CD80/86.

M. G. Agadjanyan, M. A. Chattergoon, M. J. Holterman, B. Monzavi-Karbassi, J. J. Kim, T. Dentchev, D. Wilson, V. Ayyavoo, L. J. Montaner, T. Kieber-Emmons, et al. (2003)
J. Immunol. 171, 4311-4319
 |  Abstract »  |  Full Text »  |  PDF »

Altered patterns of gene expression distinguishing ascending aortic aneurysms from abdominal aortic aneurysms: complementary DNA expression profiling in the molecular characterization of aortic disease.

T. S. Absi, T. M. Sundt III, W. S. Tung, M. Moon, J. K. Lee, R. R. Damiano Jr, and R. W. Thompson (2003)
J. Thorac. Cardiovasc. Surg. 126, 344-357
 |  Abstract »  |  Full Text »  |  PDF »

Selective Regulation of Mature IgG1 Transcription by CD86 and {beta}2-Adrenergic Receptor Stimulation.

J. R. Podojil and V. M. Sanders (2003)
J. Immunol. 170, 5143-5151
 |  Abstract »  |  Full Text »  |  PDF »

Crystal structure of the receptor-binding domain of human B7-2: Insights into organization and signaling.

X. Zhang, J.-C. D. Schwartz, S. C. Almo, and S. G. Nathenson (2003)
PNAS 100, 2586-2591
 |  Abstract »  |  Full Text »  |  PDF »

Naturally Occurring Human IgM Antibody That Binds B7-DC and Potentiates T Cell Stimulation by Dendritic Cells.

S. Radhakrishnan, L. T. Nguyen, B. Ciric, D. R. Ure, B. Zhou, K. Tamada, H. Dong, S.-Y. Tseng, T. Shin, D. M. Pardoll, et al. (2003)
J. Immunol. 170, 1830-1838
 |  Abstract »  |  Full Text »  |  PDF »

Contribution of Interleukin-12 (IL-12) and the CD28/B7 and CD40/CD40 Ligand Pathways to the Development of a Pathological T-Cell Response in IL-10-Deficient Mice.

U. Wille, E. N. Villegas, L. Craig, R. Peach, and C. A. Hunter (2002)
Infect. Immun. 70, 6940-6947
 |  Abstract »  |  Full Text »  |  PDF »

Chimeric Co-stimulatory Molecules That Selectively Act through CD28 or CTLA-4 on Human T Cells.

S. Lazetic, S. R. Leong, J. C-C. Chang, R. Ong, G. Dawes, and J. Punnonen (2002)
J. Biol. Chem. 277, 38660-38668
 |  Abstract »  |  Full Text »  |  PDF »

Evidence That Glycoprotein 96 (B2), a Stress Protein, Functions as a Th2-Specific Costimulatory Molecule.

P. P. Banerjee, D. S. Vinay, A. Mathew, M. Raje, V. Parekh, D. V. R. Prasad, A. Kumar, D. Mitra, and G. C. Mishra (2002)
J. Immunol. 169, 3507-3518
 |  Abstract »  |  Full Text »  |  PDF »

B Cell Receptor- and {beta}2-Adrenergic Receptor-Induced Regulation of B7-2 (CD86) Expression in B Cells.

A. P. Kohm, A. Mozaffarian, and V. M. Sanders (2002)
J. Immunol. 168, 6314-6322
 |  Abstract »  |  Full Text »  |  PDF »

IRTAs: a new family of immunoglobulinlike receptors differentially expressed in B cells.

I. Miller, G. Hatzivassiliou, G. Cattoretti, C. Mendelsohn, and R. Dalla-Favera (2002)
Blood 99, 2662-2669
 |  Abstract »  |  Full Text »  |  PDF »

Effect of Administration of CTLA4-Ig as Protein or cDNA on Corneal Allograft Survival.

R. M. Comer, W. J. King, N. Ardjomand, S. Theoharis, A. J. T. George, and D. F. P. Larkin (2002)
Invest. Ophthalmol. Vis. Sci. 43, 1095-1103
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Role of CD80 and CD86 in the Regulation of the Activation of B Cell and B Cell Lymphoma.

S. Suvas, V. Singh, S. Sahdev, H. Vohra, and J. N. Agrewala (2002)
J. Biol. Chem. 277, 7766-7775
 |  Abstract »  |  Full Text »  |  PDF »

Blockade of B7/CD28 in mixed lymphocyte reaction cultures results in the generation of alternatively activated macrophages, which suppress T-cell responses.

D. Tzachanis, A. Berezovskaya, L. M. Nadler, and V. A. Boussiotis (2002)
Blood 99, 1465-1473
 |  Abstract »  |  Full Text »  |  PDF »

Induction of tolerance in autoimmune diseases by hematopoietic stem cell transplantation: getting closer to a cure?.

R. K. Burt, S. Slavin, W. H. Burns, and A. M. Marmont (2002)
Blood 99, 768-784
 |  Abstract »  |  Full Text »  |  PDF »

Soluble CD26/Dipeptidyl Peptidase IV Induces T Cell Proliferation Through CD86 Up-Regulation on APCs.

K. Ohnuma, Y. Munakata, T. Ishii, S. Iwata, S. Kobayashi, O. Hosono, H. Kawasaki, N. H. Dang, and C. Morimoto (2001)
J. Immunol. 167, 6745-6755
 |  Abstract »  |  Full Text »  |  PDF »

Norepinephrine and beta 2-Adrenergic Receptor Stimulation Regulate CD4+ T and B Lymphocyte Function in Vitro and in Vivo.

A. P. Kohm and V. M. Sanders (2001)
Pharmacol. Rev. 53, 487-525
 |  Abstract »  |  Full Text »  |  PDF »

Requirement of B7-Mediated Costimulation in the Induction of Experimental Autoimmune Anterior Uveitis.

H. Shao, M.-D. Woon, S. Nakamura, J.-H. Sohn, P. A. Morton, N. S. Bora, and H. J. Kaplan (2001)
Invest. Ophthalmol. Vis. Sci. 42, 2016-2021
 |  Abstract »  |  Full Text »  |  PDF »

CD28-independent Costimulation of T Cells in Alloimmune Responses.

A. Yamada, K. Kishimoto, V. M. Dong, M. Sho, A. D. Salama, N. G. Anosova, G. Benichou, D. A. Mandelbrot, A. H. Sharpe, L. A. Turka, et al. (2001)
J. Immunol. 167, 140-146
 |  Abstract »  |  Full Text »  |  PDF »

Enhanced Activation of Human T Cells via Avipox Vector-mediated Hyperexpression of a Triad of Costimulatory Molecules in Human Dendritic Cells.

M. Zhu, H. Terasawa, J. Gulley, D. Panicali, P. Arlen, J. Schlom, and K. Y. Tsang (2001)
Cancer Res. 61, 3725-3734
 |  Abstract »  |  Full Text »

Stimulatory Effects of B7-Related Protein-1 on Cellular and Humoral Immune Responses in Mice.

J. Guo, M. Stolina, J. V. Bready, S. Yin, T. Horan, S. K. Yoshinaga, and G. Senaldi (2001)
J. Immunol. 166, 5578-5584
 |  Abstract »  |  Full Text »  |  PDF »

CD80 Costimulation Is Required for Th2 Cell Cytokine Production But Not for Antigen-Specific Accumulation and Migration into the Lung.

N. L. Harris, M. Prout, R. J. Peach, B. Fazekas de St. Groth, and F. Ronchese (2001)
J. Immunol. 166, 4908-4914
 |  Abstract »  |  Full Text »  |  PDF »

Vascular Attack by 5,6-Dimethylxanthenone-4-acetic Acid Combined with B7.1 (CD80)-mediated Immunotherapy Overcomes Immune Resistance and Leads to the Eradication of Large Tumors and Multiple Tumor Foci.

J. R. Kanwar, R. K. Kanwar, S. Pandey, L.-M. Ching, and G. W. Krissansen (2001)
Cancer Res. 61, 1948-1956
 |  Abstract »  |  Full Text »

Functional Expression of a Costimulatory B7.2 (CD86) Protein on Human Salivary Gland Epithelial Cells that Interacts with the CD28 Receptor, but Has Reduced Binding to CTLA4.

E. K. Kapsogeorgou, H. M. Moutsopoulos, and M. N. Manoussakis (2001)
J. Immunol. 166, 3107-3113
 |  Abstract »  |  Full Text »  |  PDF »

Acquisition of CD80 (B7-1) by T Cells.

H. Sabzevari, J. Kantor, A. Jaigirdar, Y. Tagaya, M. Naramura, J. W. Hodge, J. Bernon, and J. Schlom (2001)
J. Immunol. 166, 2505-2513
 |  Abstract »  |  Full Text »  |  PDF »

Functional Equivalency of B7-1 and B7-2 for Costimulating Plasmid DNA Vaccine-Elicited CTL Responses.

S. Santra, D. H. Barouch, S. S. Jackson, M. J. Kuroda, J. E. Schmitz, M. A. Lifton, A. H. Sharpe, and N. L. Letvin (2000)
J. Immunol. 165, 6791-6795
 |  Abstract »  |  Full Text »  |  PDF »

B7 Requirements for Primary and Secondary Protein- and Polysaccharide-Specific Ig Isotype Responses to Streptococcus pneumoniae.

Z.-Q. Wu, A. Q. Khan, Y. Shen, J. Schartman, R. Peach, A. Lees, J. J. Mond, W. C. Gause, and C. M. Snapper (2000)
J. Immunol. 165, 6840-6848
 |  Abstract »  |  Full Text »  |  PDF »

Construction and Characterization of Bispecific Costimulatory Molecules Containing a Minimized CD86 (B7-2) Domain and Single-Chain Antibody Fragments for Tumor Targeting.

F. Rohrbach, B. Gerstmayer, M. Biburger, and W. Wels (2000)
Clin. Cancer Res. 6, 4314-4322
 |  Abstract »  |  Full Text »  |  PDF »

Porcine CTLA4-Ig Lacks a MYPPPY Motif, Binds Inefficiently to Human B7 and Specifically Suppresses Human CD4+ T Cell Responses Costimulated by Pig But Not Human B7.

A. N. Vaughan, P. Malde, N. J. Rogers, I. M. Jackson, R. I. Lechler, and A. Dorling (2000)
J. Immunol. 165, 3175-3181
 |  Abstract »  |  Full Text »  |  PDF »

Association of B7-1 Co-Stimulation with the Development of Graft Arterial Disease : Studies Using Mice Lacking B7-1, B7-2, or B7-1/B7-2.

Y. Furukawa, D. A. Mandelbrot, P. Libby, A. H. Sharpe, and R. N. Mitchell (2000)
Am. J. Pathol. 157, 473-484
 |  Abstract »  |  Full Text »  |  PDF »

Primary Structure and Functional Characterization of a Soluble, Alternatively Spliced Form of B7-1.

S. J. Faas, M. A. Giannoni, A. P. Mickle, C. L. Kiesecker, D. J. Reed, D. Wu, W. L. Fodor, J. P. Mueller, L. A. Matis, and R. P. Rother (2000)
J. Immunol. 164, 6340-6348
 |  Abstract »  |  Full Text »  |  PDF »

Th1 Versus Th2 Immune Responses in Autoimmune Lacrimal Gland Disease in MRL/Mp Mice.

D. A. Jabs, B. Lee, J. A. Whittum–Hudson, and R. A. Prendergast (2000)
Invest. Ophthalmol. Vis. Sci. 41, 826-831
 |  Abstract »  |  Full Text »

The B7/CD28/CTLA4 T-Cell Activation Pathway . Implications for Inflammatory Lung Disease.

J. M. Green (2000)
Am. J. Respir. Cell Mol. Biol. 22, 261-264
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Naive CD8+ T Cells Do Not Require Costimulation for Proliferation and Differentiation into Cytotoxic Effector Cells.

B. Wang, R. Maile, R. Greenwood, E. J. Collins, and J. A. Frelinger (2000)
J. Immunol. 164, 1216-1222
 |  Abstract »  |  Full Text »  |  PDF »

Development of Human T-Cell Leukemia Virus Type 1-Transformed Tumors in Rats following Suppression of T-Cell Immunity by CD80 and CD86 Blockade.

S. Hanabuchi, T. Ohashi, Y. Koya, H. Kato, F. Takemura, K. Hirokawa, T. Yoshiki, H. Yagita, K. Okumura, and M. Kannagi (2000)
J. Virol. 74, 428-435
 |  Abstract »  |  Full Text »  |  PDF »

AILIM/ICOS: a novel lymphocyte adhesion molecule.

T. Tamatani, K. Tezuka, and N. Hanzawa-Higuchi (2000)
Int. Immunol. 12, 51-55
 |  Abstract »  |  Full Text »  |  PDF »

Danger and OX40 Receptor Signaling Synergize to Enhance Memory T Cell Survival by Inhibiting Peripheral Deletion.

J. R. Maxwell, A. Weinberg, R. A. Prell, and A. T. Vella (2000)
J. Immunol. 164, 107-112
 |  Abstract »  |  Full Text »  |  PDF »

CD28 Costimulation Mediates T Cell Expansion Via IL-2-Independent and IL-2-Dependent Regulation of Cell Cycle Progression.

L. J. Appleman, A. Berezovskaya, I. Grass, and V. A. Boussiotis (2000)
J. Immunol. 164, 144-151
 |  Abstract »  |  Full Text »  |  PDF »

The role of CTLA-4 in tolerance induction and Ttigen administration cell differentiation in experimental autoimmune encephalomyelitis: i.v. antigen administration.

R. B. Ratts, L. R. Arredondo, P. Bittner, P. J. Perrin, A. E. Lovett-Racke, and M. K. Racke (1999)
Int. Immunol. 11, 1889-1896
 |  Abstract »  |  Full Text »  |  PDF »

Molecular and Functional Characterization of Mouse Signaling Lymphocytic Activation Molecule (SLAM): Differential Expression and Responsiveness in Th1 and Th2 Cells.

A. G. Castro, T. M. Hauser, B. G. Cocks, J. Abrams, S. Zurawski, T. Churakova, F. Zonin, D. Robinson, S. G. Tangye, G. Aversa, et al. (1999)
J. Immunol. 163, 5860-5870
 |  Abstract »  |  Full Text »  |  PDF »

VIP and PACAP Differentially Regulate the Costimulatory Activity of Resting and Activated Macrophages Through the Modulation of B7.1 and B7.2 Expression.

M. Delgado, W. Sun, J. Leceta, and D. Ganea (1999)
J. Immunol. 163, 4213-4223
 |  Abstract »  |  Full Text »  |  PDF »

The Future of Organ and Tissue Transplantation: Can T-Cell Costimulatory Pathway Modifiers Revolutionize the Prevention of Graft Rejection?.

D. M. Harlan and A. D. Kirk (1999)
JAMA 282, 1076-1082
 |  Abstract »  |  Full Text »  |  PDF »

Human Fibroblasts Transduced with CD80 or CD86 Efficiently trans-Costimulate CD4+ and CD8+ T Lymphocytes in HLA-Restricted Reactions: Implications for Immune Augmentation Cancer Therapy and Autoimmunity.

J. A. Smythe, P. D. Fink, G. J. Logan, J. Lees, P. B. Rowe, and I. E. Alexander (1999)
J. Immunol. 163, 3239-3249
 |  Abstract »  |  Full Text »  |  PDF »

Enhanced B7-2 Gene Expression by Interferon-gamma in Human Monocytic Cells Is Controlled Through Transcriptional and Posttranscriptional Mechanisms.

R.E. Curiel, C.S. Garcia, S. Rottschafer, M.C. Bosco, and I. Espinoza-Delgado (1999)
Blood 94, 1782-1789
 |  Abstract »  |  Full Text »  |  PDF »

CD28, IL-2-Independent Costimulatory Pathways for CD8 T Lymphocyte Activation.

H. Sepulveda, A. Cerwenka, T. Morgan, and R. W. Dutton (1999)
J. Immunol. 163, 1133-1142
 |  Abstract »  |  Full Text »  |  PDF »

Blockade of CD28 During In Vitro Activation of Encephalitogenic T Cells or After Disease Onset Ameliorates Experimental Autoimmune Encephalomyelitis.

P. J. Perrin, C. H. June, J. H. Maldonado, R. B. Ratts, and M. K. Racke (1999)
J. Immunol. 163, 1704-1710
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Autoimmunity in Ig Transgenic Mice.

S. Shinde, R. Gee, S. Santulli-Marotto, L. K. Bockenstedt, S. H. Clarke, and M. J. Mamula (1999)
J. Immunol. 162, 7519-7524
 |  Abstract »  |  Full Text »  |  PDF »

Vaccine therapy for cancer—fact or fiction?.

T.R.J. Evans and S.B. Kaye (1999)
QJM 92, 299-307
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Combination Gene Therapy with CD86 and the MHC Class II Transactivator in the Control of Lung Tumor Growth.

B. K. Martin, J. G. Frelinger, and J. P.-Y. Ting (1999)
J. Immunol. 162, 6663-6670
 |  Abstract »  |  Full Text »  |  PDF »

Expression and Contribution of B7-1 (CD80) and B7-2 (CD86) in the Early Immune Response to Leishmania major Infection.

M. M. Elloso and P. Scott (1999)
J. Immunol. 162, 6708-6715
 |  Abstract »  |  Full Text »  |  PDF »

Autoantibodies to T Cell Costimulatory Molecules in Systemic Autoimmune Diseases.

T. Matsui, M. Kurokawa, T. Kobata, S. Oki, M. Azuma, S. Tohma, T. Inoue, K. Yamamoto, K. Nishioka, and T. Kato (1999)
J. Immunol. 162, 4328-4335
 |  Abstract »  |  Full Text »  |  PDF »

B7-2 Expressed on EL4 Lymphoma Suppresses Antitumor Immunity by an Interleukin 4-dependent Mechanism.

C. Stremmel, E.A. Greenfield, E. Howard, G.J. Freeman, and V.K. Kuchroo (1999)
J. Exp. Med. 189, 919-930
 |  Abstract »  |  Full Text »  |  PDF »

Cancer Vaccines.

T. F. Greten and E. M. Jaffee (1999)
J. Clin. Oncol. 17, 1047
 |  Abstract »  |  Full Text »  |  PDF »

Experimental Murine Schistosomiasis in the Absence of B7 Costimulatory Molecules: Reversal of Elicited T Cell Cytokine Profile and Partial Inhibition of Egg Granuloma Formation.

H. J. Hernandez, A. H. Sharpe, and M. J. Stadecker (1999)
J. Immunol. 162, 2884-2889
 |  Abstract »  |  Full Text »  |  PDF »

The Role of CD80, CD86, and CTLA4 in Alloimmune Responses and the Induction of Long-Term Allograft Survival.

T. A. Judge, Z. Wu, X.-G. Zheng, A. H. Sharpe, M. H. Sayegh, and L. A. Turka (1999)
J. Immunol. 162, 1947-1951
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CD40 Activation Boosts T Cell Immunity In Vivo by Enhancing T Cell Clonal Expansion and Delaying Peripheral T Cell Deletion.

J. R. Maxwell, J. D. Campbell, C. H. Kim, and A. T. Vella (1999)
J. Immunol. 162, 2024-2034
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B7 Costimulation Is Required for IL-5 and IL-13 Secretion by Bronchial Biopsy Tissue of Atopic Asthmatic Subjects in Response to Allergen Stimulation.

Z. Jaffar, K. Roberts, A. Pandit, P. Linsley, R. Djukanovic, and S. Holgate (1999)
Am. J. Respir. Cell Mol. Biol. 20, 153-162
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T Cell Proliferation-Augmenting Activities of the Gene 3 Protein Derived from a Phage Library Clone with CD80-Binding Activity.

T. Fukumoto, N. Torigoe, Y. Ito, Y. Kajiwara, and K. Sugimura (1998)
J. Immunol. 161, 6622-6628
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Human Muscle Cells Express a Functional Costimulatory Molecule Distinct from B7.1 (CD80) and B7.2 (CD86) In Vitro and in Inflammatory Lesions.

L. Behrens, M. Kerschensteiner, T. Misgeld, N. Goebels, H. Wekerle, and R. Hohlfeld (1998)
J. Immunol. 161, 5943-5951
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The Role of the CD40 Pathway in Alloantigen-Induced Hyporesponsiveness In Vivo.

M. Niimi, T. C. Pearson, C. P. Larsen, D. Z. Alexander, D. Hollenbaugh, A. Aruffo, P. S. Linsley, E. Thomas, K. Campbell, W. C. Fanslow, et al. (1998)
J. Immunol. 161, 5331-5337
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Qualitative and Quantitative Effects of CD28/B7-Mediated Costimulation on Naive T Cells In Vitro.

S. P. Manickasingham, S. M. Anderton, C. Burkhart, and D. C. Wraith (1998)
J. Immunol. 161, 3827-3835
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The BB1 Monoclonal Antibody Recognizes Both Cell Surface CD74 (MHC Class II-Associated Invariant Chain) as Well as B7-1 (CD80), Resolving the Question Regarding a Third CD28/CTLA-4 Counterreceptor.

G. J. Freeman, A. A. Cardoso, V. A. Boussiotis, A. Anumanthan, R. W. Groves, T. S. Kupper, E. A. Clark, and L. M. Nadler (1998)
J. Immunol. 161, 2708-2715
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Heterogeneity of Dendritic Cells in Human Superficial Lymph Node : In Vitro Maturation of Immature Dendritic Cells intoMature or Activated Interdigitating Reticulum Cells.

K. Takahashi, K. Asagoe, J. Zaishun, H. Yanai, T. Yoshino, K. Hayashi, and T. Akagi (1998)
Am. J. Pathol. 153, 745-755
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Autoimmunity Without Diabetes in Transgenic Mice Expressing {beta} Cell-Specific CD86, But Not CD80: Parameters that Trigger Progression to Diabetes.

S. Guerder, E. E. Eynon, and R. A. Flavell (1998)
J. Immunol. 161, 2128-2140
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Fas-independent death of activated CD4+ T lymphocytes induced by CTLA-4 crosslinking.

P. Scheipers and H. Reiser (1998)
PNAS 95, 10083-10088
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Identification of a Dynamic Intracellular Reservoir of CD86 Protein in Peripheral Blood Monocytes That Is Not Associated with the Golgi Complex.

C. Smyth, G. Logan, R. P. Weinberger, P. B. Rowe, I. E. Alexander, and J. A. Smythe (1998)
J. Immunol. 160, 5390-5396
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Expression of CD86 on Human Marrow CD34+ Cells Identifies Immunocompetent Committed Precursors of Macrophages and Dendritic Cells.

R. E. Ryncarz and C. Anasetti (1998)
Blood 91, 3892-3900
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T:T Antigen Presentation by Activated Murine CD8+ T Cells Induces Anergy and Apoptosis.

J.-G. Chai, I. Bartok, D. Scott, J. Dyson, and R. Lechler (1998)
J. Immunol. 160, 3655-3665
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Purified MHC Class I and Peptide Complexes Activate Naive CD8+ T Cells Independently of the CD28/B7 and LFA-1/ICAM-1 Costimulatory Interactions.

J. S. Goldstein, T. Chen, M. Brunswick, H. Mostowsky, and S. Kozlowski (1998)
J. Immunol. 160, 3180-3187
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Effects of In Vivo Administration of Anti–B7-1/B7-2 Monoclonal Antibodies on Murine Acute Myocarditis Caused by Coxsackievirus B3.

Y. Seko, N. Takahashi, M. Azuma, H. Yagita, K. Okumura, and Y. Yazaki (1998)
Circ. Res. 82, 613-618
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A Double Recombinant Adenovirus Expressing the Costimulatory Molecule B7-1 (Murine) and Human IL-2 Induces Complete Tumor Regression in a Murine Breast Adenocarcinoma Model.

P. C. R. Emtage, Y. Wan, J. L. Bramson, F. L. Graham, and J. Gauldie (1998)
J. Immunol. 160, 2531-2538
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Role of CD80 (B7.1) and CD86 (B7.2) in the Immune Response to an Intracellular Pathogen.

C. S. Subauste, R. de Waal Malefyt, and F. Fuh (1998)
J. Immunol. 160, 1831-1840
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Importance of the B7-2 Molecule for Low Dose Melphalan-Induced Acquisition of Tumor-Eradicating Immunity by Mice Bearing a Large MOPC-315 Tumor.

M. B. Mokyr, T. V. Kalinichenko, L. Gorelik, and J. A. Bluestone (1998)
J. Immunol. 160, 1866-1874
 |  Abstract »  |  Full Text »  |  PDF »

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