Science 29 October 1993: Vol. 262. no. 5134, pp. 747 - 750 DOI: 10.1126/science.8235596

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Articles

Molecular footprints of a germinal center derivation of human IgM+(IgD+)CD27+ B cells and the dynamics of memory B cell generation.

M. Seifert and R. Kuppers (2009)
J. Exp. Med. 206, 2659-2669
 |  Abstract »  |  Full Text »  |  PDF »

Male-Specific Hepatic Bcl6: Growth Hormone-Induced Block of Transcription Elongation in Females and Binding to Target Genes Inversely Coordinated with STAT5.

R. D. Meyer, E. V. Laz, T. Su, and D. J. Waxman (2009)
Mol. Endocrinol. 23, 1914-1926
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IFN Regulatory Factor 8 Regulates MDM2 in Germinal Center B Cells.

J. X. Zhou, C. H. Lee, C. F. Qi, H. Wang, Z. Naghashfar, S. Abbasi, and H. C. Morse III (2009)
J. Immunol. 183, 3188-3194
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BCL6 suppression of BCL2 via Miz1 and its disruption in diffuse large B cell lymphoma.

M. Saito, U. Novak, E. Piovan, K. Basso, P. Sumazin, C. Schneider, M. Crespo, Q. Shen, G. Bhagat, A. Califano, et al. (2009)
PNAS 106, 11294-11299
 |  Abstract »  |  Full Text »  |  PDF »

A peptomimetic inhibitor of BCL6 with potent antilymphoma effects in vitro and in vivo.

L. C. Cerchietti, S. N. Yang, R. Shaknovich, K. Hatzi, J. M. Polo, A. Chadburn, S. F. Dowdy, and A. Melnick (2009)
Blood 113, 3397-3405
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B lymphocytes: how they develop and function.

T. W. LeBien and T. F. Tedder (2008)
Blood 112, 1570-1580
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CtBP Is an Essential Corepressor for BCL6 Autoregulation.

L. M. Mendez, J. M. Polo, J. J. Yu, M. Krupski, B. B. Ding, A. Melnick, and B. H. Ye (2008)
Mol. Cell. Biol. 28, 2175-2186
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BCL6 Represses Smad Signaling in Transforming Growth Factor-{beta} Resistance.

D. Wang, J. Long, F. Dai, M. Liang, X.-H. Feng, and X. Lin (2008)
Cancer Res. 68, 783-789
 |  Abstract »  |  Full Text »  |  PDF »

Differential Gene Expression between Sensory Neocortical Areas: Potential Roles for Ten_m3 and Bcl6 in Patterning Visual and Somatosensory Pathways.

C. A. Leamey, K. A. Glendining, G. Kreiman, N.-D. Kang, K. H. Wang, R. Fassler, A. Sawatari, S. Tonegawa, and M. Sur (2008)
Cereb Cortex 18, 53-66
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RAR{alpha}-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemia.

F. Guidez, S. Parks, H. Wong, J. V. Jovanovic, A. Mays, A. F. Gilkes, K. I. Mills, M.-C. Guillemin, R. M. Hobbs, P. P. Pandolfi, et al. (2007)
PNAS 104, 18694-18699
 |  Abstract »  |  Full Text »  |  PDF »

The clinical presentation and prognosis of diffuse large B-cell lymphoma with t(14;18) and 8q24/c-MYC rearrangement.

S. Le Gouill, P. Talmant, C. Touzeau, A. Moreau, R. Garand, N. Juge-Morineau, F. Gaillard, T. Gastinne, N. Milpied, P. Moreau, et al. (2007)
Haematologica 92, 1335-1342
 |  Abstract »  |  Full Text »  |  PDF »

BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms.

S. Parekh, J. M. Polo, R. Shaknovich, P. Juszczynski, P. Lev, S. M. Ranuncolo, Y. Yin, U. Klein, G. Cattoretti, R. D. Favera, et al. (2007)
Blood 110, 2067-2074
 |  Abstract »  |  Full Text »  |  PDF »

The Carboxyl-terminal Fragment of Pro-HB-EGF Reverses Bcl6-mediated Gene Repression.

Y. Kinugasa, M. Hieda, M. Hori, and S. Higashiyama (2007)
J. Biol. Chem. 282, 14797-14806
 |  Abstract »  |  Full Text »  |  PDF »

Repression of the PDCD2 gene by BCL6 and the implications for the pathogenesis of human B and T cell lymphomas.

B. W. Baron, N. Zeleznik-Le, M. J. Baron, C. Theisler, D. Huo, M. D. Krasowski, M. J. Thirman, R. M. Baron, and J. M. Baron (2007)
PNAS 104, 7449-7454
 |  Abstract »  |  Full Text »  |  PDF »

Bcl6 is essential for the generation of long-term memory CD4+ T cells.

H. Ichii, A. Sakamoto, M. Arima, M. Hatano, Y. Kuroda, and T. Tokuhisa (2007)
Int. Immunol. 19, 427-433
 |  Abstract »  |  Full Text »  |  PDF »

Gene-expression profiling of systemic anaplastic large-cell lymphoma reveals differences based on ALK status and two distinct morphologic ALK+ subtypes.

L. Lamant, A. d. Reynies, M.-M. Duplantier, D. S. Rickman, F. Sabourdy, S. Giuriato, L. Brugieres, P. Gaulard, E. Espinos, and G. Delsol (2007)
Blood 109, 2156-2164
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomas.

J. M. Polo, P. Juszczynski, S. Monti, L. Cerchietti, K. Ye, J. M. Greally, M. Shipp, and A. Melnick (2007)
PNAS 104, 3207-3212
 |  Abstract »  |  Full Text »  |  PDF »

High BCL6 expression predicts better prognosis, independent of BCL6 translocation status, translocation partner, or BCL6-deregulating mutations, in gastric lymphoma.

Y.-W. Chen, X.-T. Hu, A. C. Liang, W.-Y. Au, C.-C. So, M. L. Wong, L. Shen, Q. Tao, K.-M. Chu, Y.-L. Kwong, et al. (2006)
Blood 108, 2373-2383
 |  Abstract »  |  Full Text »  |  PDF »

JunD/AP-1 and STAT3 are the major enhancer molecules for high Bcl6 expression in germinal center B cells.

E. Arguni, M. Arima, N. Tsuruoka, A. Sakamoto, M. Hatano, and T. Tokuhisa (2006)
Int. Immunol. 18, 1079-1089
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Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes..

B. Heltweg, T. Gatbonton, A. D. Schuler, J. Posakony, H. Li, S. Goehle, R. Kollipara, R. A. DePinho, Y. Gu, J. A. Simon, et al. (2006)
Cancer Res. 66, 4368-4377
 |  Abstract »  |  Full Text »  |  PDF »

Closing the loop: p53-BCL6 feedback.

I. S. Lossos (2006)
Blood 107, 1246-1247
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BCL6 is regulated by p53 through a response element frequently disrupted in B-cell non-Hodgkin lymphoma.

O. Margalit, H. Amram, N. Amariglio, A. J. Simon, S. Shaklai, G. Granot, N. Minsky, A. Shimoni, A. Harmelin, D. Givol, et al. (2006)
Blood 107, 1599-1607
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Analysis of BCL6-interacting Proteins by Tandem Mass Spectrometry.

R. R. Miles, D. K. Crockett, M. S. Lim, and K. S. J. Elenitoba-Johnson (2005)
Mol. Cell. Proteomics 4, 1898-1909
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A Putative Exonic Splicing Polymorphism in the BCL6 Gene and the Risk of Non-Hodgkin Lymphoma.

Y. Zhang, Q. Lan, N. Rothman, Y. Zhu, S. H. Zahm, S. S. Wang, T. R. Holford, B. Leaderer, P. Boyle, B. Zhang, et al. (2005)
J Natl Cancer Inst 97, 1616-1618
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Molecular Pathogenesis of Diffuse Large B-Cell Lymphoma.

I. S. Lossos (2005)
J. Clin. Oncol. 23, 6351-6357
 |  Abstract »  |  Full Text »  |  PDF »

Advances in the biology and therapy of diffuse large B-cell lymphoma: moving toward a molecularly targeted approach.

J. S. Abramson and M. A. Shipp (2005)
Blood 106, 1164-1174
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The Theoretical Basis of Transcriptional Therapy of Cancer: Can It Be Put Into Practice?.

A. M. Melnick, K. Adelson, and J. D. Licht (2005)
J. Clin. Oncol. 23, 3957-3970
 |  Abstract »  |  Full Text »  |  PDF »

The human BCL6 transgene promotes the development of lymphomas in the mouse.

B. W. Baron, J. Anastasi, A. Montag, D. Huo, R. M. Baron, T. Karrison, M. J. Thirman, S. K. Subudhi, R. K. Chin, D. W. Felsher, et al. (2004)
PNAS 101, 14198-14203
 |  Abstract »  |  Full Text »  |  PDF »

Cytogenetic Alterations Affecting BCL6 Are Predominantly Found in Follicular Lymphomas Grade 3B with a Diffuse Large B-Cell Component.

T. Katzenberger, G. Ott, T. Klein, J. Kalla, H. K. Muller-Hermelink, and M. M. Ott (2004)
Am. J. Pathol. 165, 481-490
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Bcl6 Acts as an Amplifier for the Generation and Proliferative Capacity of Central Memory CD8+ T Cells.

H. Ichii, A. Sakamoto, Y. Kuroda, and T. Tokuhisa (2004)
J. Immunol. 173, 883-891
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Lymphoma B Cells Evade Apoptosis through the TNF Family Members BAFF/BLyS and APRIL.

B. He, A. Chadburn, E. Jou, E. J. Schattner, D. M. Knowles, and A. Cerutti (2004)
J. Immunol. 172, 3268-3279
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E{micro}-BRD2 transgenic mice develop B-cell lymphoma and leukemia.

R. J. Greenwald, J. R. Tumang, A. Sinha, N. Currier, R. D. Cardiff, T. L. Rothstein, D. V. Faller, and G. V. Denis (2004)
Blood 103, 1475-1484
 |  Abstract »  |  Full Text »  |  PDF »

BCL6 gene translocation in follicular lymphoma: a harbinger of eventual transformation to diffuse aggressive lymphoma.

T. Akasaka, I. S. Lossos, and R. Levy (2003)
Blood 102, 1443-1448
 |  Abstract »  |  Full Text »  |  PDF »

BCL6 Controls the Expression of the B7-1/CD80 Costimulatory Receptor in Germinal Center B Cells.

H. Niu, G. Cattoretti, and R. Dalla-Favera (2003)
J. Exp. Med. 198, 211-221
 |  Abstract »  |  Full Text »  |  PDF »

Bcl6 Is a Transcriptional Repressor for the IL-18 Gene.

N. Takeda, M. Arima, N. Tsuruoka, S. Okada, M. Hatano, A. Sakamoto, Y. Kohno, and T. Tokuhisa (2003)
J. Immunol. 171, 426-431
 |  Abstract »  |  Full Text »  |  PDF »

The Histone Deacetylase 9 Gene Encodes Multiple Protein Isoforms.

K. Petrie, F. Guidez, L. Howell, L. Healy, S. Waxman, M. Greaves, and A. Zelent (2003)
J. Biol. Chem. 278, 16059-16072
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Mutations of the BCL6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphoma.

L. Pasqualucci, A. Migliazza, K. Basso, J. Houldsworth, R. S. K. Chaganti, and R. Dalla-Favera (2003)
Blood 101, 2914-2923
 |  Abstract »  |  Full Text »  |  PDF »

Typing the Histogenetic Origin of the Tumor Cells of Lymphocyte-rich Classical Hodgkin's Lymphoma in Relation to Tumor Cells of Classical and Lymphocyte-predominance Hodgkin's Lymphoma.

A. Brauninger, H.-H. Wacker, K. Rajewsky, R. Kuppers, and M.-L. Hansmann (2003)
Cancer Res. 63, 1644-1651
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Lymphocyte Apoptosis by Interferon Regulatory Factor 4 (IRF-4).

J. C. Fanzo, C.-M. Hu, S. Y. Jang, and A. B. Pernis (2003)
J. Exp. Med. 197, 303-314
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Novel Cryptic Translocations Involving IGH in B-Cell Non-Hodgkin's Lymphomas.

A. Gozzetti, E. M. Davis, R. Espinosa III, A. A. Fernald, J. Anastasi, and M. M. Le Beau (2002)
Cancer Res. 62, 5523-5527
 |  Abstract »  |  Full Text »  |  PDF »

Alternative Translocation Breakpoint Cluster Region 5' to BCL-6 in B-cell Non-Hodgkin's Lymphoma.

M. P. Butler, S. Iida, D. Capello, D. Rossi, P. H. Rao, P. Nallasivam, D. C. Louie, S. Chaganti, T. Au, R. D. Gascoyne, et al. (2002)
Cancer Res. 62, 4089-4094
 |  Abstract »  |  Full Text »  |  PDF »

A Putative Silencer Element in the IL-5 Gene Recognized by Bcl6.

M. Arima, H. Toyama, H. Ichii, S. Kojima, S. Okada, M. Hatano, G. Cheng, M. Kubo, T. Fukuda, and T. Tokuhisa (2002)
J. Immunol. 169, 829-836
 |  Abstract »  |  Full Text »  |  PDF »

The Effects of the Fanconi Anemia Zinc Finger (FAZF) on Cell Cycle, Apoptosis, and Proliferation Are Differentiation Stage-specific.

M.-S. Dai, N. Chevallier, S. Stone, M. C. Heinrich, M. McConnell, T. Reuter, H. E. Broxmeyer, J. D. Licht, L. Lu, and M. E. Hoatlin (2002)
J. Biol. Chem. 277, 26327-26334
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Bethesda proposals for classification of lymphoid neoplasms in mice.

H. C. Morse III, M. R. Anver, T. N. Fredrickson, D. C. Haines, A. W. Harris, N. L. Harris, E. S. Jaffe, S. C. Kogan, I. C. M. MacLennan, P. K. Pattengale, et al. (2002)
Blood 100, 246-258
 |  Abstract »  |  Full Text »  |  PDF »

Class II Histone Deacetylases Are Directly Recruited by BCL6 Transcriptional Repressor.

C. Lemercier, M.-P. Brocard, F. Puvion-Dutilleul, H.-Y. Kao, O. Albagli, and S. Khochbin (2002)
J. Biol. Chem. 277, 22045-22052
 |  Abstract »  |  Full Text »  |  PDF »

Insights into the molecular pathogenesis of follicular lymphoma arising from analysis of geographic variation.

J. J. Biagi and J. F. Seymour (2002)
Blood 99, 4265-4275
 |  Abstract »  |  Full Text »  |  PDF »

Critical Residues within the BTB Domain of PLZF and Bcl-6 Modulate Interaction with Corepressors.

A. Melnick, G. Carlile, K. F. Ahmad, C.-L. Kiang, C. Corcoran, V. Bardwell, G. G. Prive, and J. D. Licht (2002)
Mol. Cell. Biol. 22, 1804-1818
 |  Abstract »  |  Full Text »  |  PDF »

A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19ARF-p53 signaling.

A. Shvarts, T. R. Brummelkamp, F. Scheeren, E. Koh, G. Q. Daley, H. Spits, and R. Bernards (2002)
Genes & Dev. 16, 681-686
 |  Abstract »  |  Full Text »  |  PDF »

Isolation and Characterization of XKaiso, a Transcriptional Repressor That Associates with the Catenin Xp120ctn in Xenopus laevis.

S. W. Kim, X. Fang, H. Ji, A. F. Paulson, J. M. Daniel, M. Ciesiolka, F. van Roy, and P. D. McCrea (2002)
J. Biol. Chem. 277, 8202-8208
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of Two Novel Nuclear BTB/POZ Domain Zinc Finger Isoforms. ASSOCIATION WITH DIFFERENTIATION OF HIPPOCAMPAL NEURONS, CEREBELLAR GRANULE CELLS, AND MACROGLIA.

C. Mitchelmore, K. M. Kjarulff, H. C. Pedersen, J. V. Nielsen, T. E. Rasmussen, M. F. Fisker, B. Finsen, K. M. Pedersen, and N. A. Jensen (2002)
J. Biol. Chem. 277, 7598-7609
 |  Abstract »  |  Full Text »  |  PDF »

Sustained Expression of the Novel EBV-Induced Zinc Finger Gene, ZNFEB, Is Critical for the Transition of B Lymphocyte Activation to Oncogenic Growth Transformation.

C. E. Tune, M. Pilon, Y. Saiki, and H.-M. Dosch (2002)
J. Immunol. 168, 680-688
 |  Abstract »  |  Full Text »  |  PDF »

Proteins encoded by genes involved in chromosomal alterations in lymphoma and leukemia: clinical value of their detection by immunocytochemistry.

B. Falini and D. Y. Mason (2002)
Blood 99, 409-426
 |  Abstract »  |  Full Text »  |  PDF »

SIV-associated Lymphomas in Rhesus Monkeys (Macaca mulatta) in Comparison with HIV-associated Lymphomas.

K. Kahnt, K. Matz-Rensing, P. Hofmann, C. Stahl-Hennig, and F.-J. Kaup (2002)
Vet. Pathol. 39, 42-55
 |  Abstract »  |  Full Text »  |  PDF »

Expression of a single gene, BCL-6, strongly predicts survival in patients with diffuse large B-cell lymphoma.

I. S. Lossos, C. D. Jones, R. Warnke, Y. Natkunam, H. Kaizer, J. L. Zehnder, R. Tibshirani, and R. Levy (2001)
Blood 98, 945-951
 |  Abstract »  |  Full Text »  |  PDF »

Stage-Specific Modulation of IFN-Regulatory Factor 4 Function by Kruppel-Type Zinc Finger Proteins.

S. Gupta, A. Anthony, and A. B. Pernis (2001)
J. Immunol. 166, 6104-6111
 |  Abstract »  |  Full Text »  |  PDF »

Cloning and Characterization of CLLD6, CLLD7, and CLLD8, Novel Candidate Genes for Leukemogenesis at Chromosome 13q14, a Region Commonly Deleted in B-Cell Chronic Lymphocytic Leukemia.

H. Mabuchi, H. Fujii, G. Calin, H. Alder, M. Negrini, L. Rassenti, T. J. Kipps, F. Bullrich, and C. M. Croce (2001)
Cancer Res. 61, 2870-2877
 |  Abstract »  |  Full Text »

New Approaches to Lymphoma Diagnosis.

N. L. Harris, H. Stein, S. E. Coupland, M. Hummel, R. D. Favera, L. Pasqualucci, and W. C. Chan (2001)
Hematology 2001, 194-220
 |  Abstract »  |  Full Text »  |  PDF »

BCL-6 protein is expressed in precursor T-cell lymphoblastic lymphoma and in prenatal and postnatal thymus.

E. Hyjek, A. Chadburn, Y. F. Liu, E. Cesarman, and D. M. Knowles (2001)
Blood 97, 270-276
 |  Abstract »  |  Full Text »  |  PDF »

Suppression of Signal Transducer and Activator of Transcription 3-Dependent B Lymphocyte Terminal Differentiation by Bcl-6.

R. Reljic, S. D. Wagner, L. J. Peakman, and D. T. Fearon (2000)
J. Exp. Med. 192, 1841-1848
 |  Abstract »  |  Full Text »  |  PDF »

Immunodeficiency, Immunosuppression, and Susceptibility to Neoplasms.

R. S. Schwartz (2000)
J Natl Cancer Inst Monographs 2000, 5-9
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DNA Replication Progresses on the Periphery of Nuclear Aggregates Formed by the BCL6 Transcription Factor.

O. Albagli, C. Lindon, D. Lantoine, S. Quief, E. Puvion, C. Pinset, and F. Puvion-Dutilleul (2000)
Mol. Cell. Biol. 20, 8560-8570
 |  Abstract »  |  Full Text »

Molecular Diagnostic Approach to Non-Hodgkin's Lymphoma.

D. A. Arber (2000)
J. Mol. Diagn. 2, 178-190
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Functional studies of the BTB domain in the Drosophila GAGA and Mod(mdg4) proteins.

D. Read, M. J. Butte, A. F. Dernburg, M. Frasch, and T. B. Kornberg (2000)
Nucleic Acids Res. 28, 3864-3870
 |  Abstract »  |  Full Text »  |  PDF »

Nonimmunoglobulin (non-Ig)/BCL6 gene fusion in diffuse large B-cell lymphoma results in worse prognosis than Ig/BCL6.

T. Akasaka, C. Ueda, M. Kurata, H. Akasaka, H. Yamabe, T. Uchiyama, and H. Ohno (2000)
Blood 96, 2907-2909
 |  Abstract »  |  Full Text »  |  PDF »

In-Depth Mutational Analysis of the Promyelocytic Leukemia Zinc Finger BTB/POZ Domain Reveals Motifs and Residues Required for Biological and Transcriptional Functions.

A. Melnick, K. F. Ahmad, S. Arai, A. Polinger, H. Ball, K. L. Borden, G. W. Carlile, G. G. Prive, and J. D. Licht (2000)
Mol. Cell. Biol. 20, 6550-6567
 |  Abstract »  |  Full Text »

The N-terminal BTB/POZ Domain and C-Terminal Sequences Are Essential for Tramtrack69 to Specify Cell Fate in the Developing Drosophila Eye.

Y. Wen, D. Nguyen, Y. Li, and Z.-C. Lai (2000)
Genetics 156, 195-203
 |  Abstract »  |  Full Text »

The role of immunoglobulin translocations in the pathogenesis of B-cell malignancies.

T. G. Willis and M. J. S. Dyer (2000)
Blood 96, 808-822
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B Cell Receptor Engagement and T Cell Contact Induce bcl-6 Somatic Hypermutation in Human B Cells: Identity with Ig Hypermutation.

H. Zan, Z. Li, K. Yamaji, P. Dramitinos, A. Cerutti, and P. Casali (2000)
J. Immunol. 165, 830-839
 |  Abstract »  |  Full Text »  |  PDF »

Higher-grade transformation of follicle center lymphoma is associated with somatic mutation of the 5' noncoding regulatory region of the BCL-6 gene.

I. S. Lossos and R. Levy (2000)
Blood 96, 635-639
 |  Abstract »  |  Full Text »  |  PDF »

Somatic mutation of bcl-6 genes can occur in the absence of VH mutations in chronic lymphocytic leukemia.

S. S. Sahota, Z. Davis, T. J. Hamblin, and F. K. Stevenson (2000)
Blood 95, 3534-3540
 |  Abstract »  |  Full Text »  |  PDF »

Evi9 Encodes a Novel Zinc Finger Protein That Physically Interacts with BCL6, a Known Human B-Cell Proto-Oncogene Product.

T. Nakamura, Y. Yamazaki, Y. Saiki, M. Moriyama, D. A. Largaespada, N. A. Jenkins, and N. G. Copeland (2000)
Mol. Cell. Biol. 20, 3178-3186
 |  Abstract »  |  Full Text »

Molecular Anatomy of BCL6 Translocations Revealed by Long-Distance Polymerase Chain Reaction-based Assays.

H. Akasaka, T. Akasaka, M. Kurata, C. Ueda, A. Shimizu, T. Uchiyama, and H. Ohno (2000)
Cancer Res. 60, 2335-2341
 |  Abstract »  |  Full Text »

Variants of STAT6 (signal transducer and activator of transcription 6) in atopic asthma.

P-S GAO, X-Q MAO, M H ROBERTS, Y ARINOBU, M AKAIWA, T ENOMOTO, Y DAKE, M KAWAI, S SASAKI, N HAMASAKI, et al. (2000)
J. Med. Genet. 37, 380a-382
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MUC1 dysregulation as the consequence of a t(1;14)(q21;q32) translocation in an extranodal lymphoma.

F. Gilles, A. Goy, Y. Remache, P. Shue, and A. D. Zelenetz (2000)
Blood 95, 2930-2936
 |  Abstract »  |  Full Text »  |  PDF »

The Ikaros gene, a central regulator of lymphoid differentiation, fuses to the BCL6 gene as a result of t(3;7)(q27;p12) translocation in a patient with diffuse large B-cell lymphoma.

Y. Hosokawa, Y. Maeda, R. Ichinohasama, I. Miura, M. Taniwaki, and M. Seto (2000)
Blood 95, 2719-2721
 |  Abstract »  |  Full Text »  |  PDF »

A Combinatorial Code for Gene Expression Generated by Transcription Factor Bach2 and MAZR (MAZ-Related Factor) through the BTB/POZ Domain.

A. Kobayashi, H. Yamagiwa, H. Hoshino, A. Muto, K. Sato, M. Morita, N. Hayashi, M. Yamamoto, and K. Igarashi (2000)
Mol. Cell. Biol. 20, 1733-1746
 |  Abstract »  |  Full Text »

Mutation analysis of the 5' noncoding regulatory region of the BCL-6 gene in non-Hodgkin lymphoma: evidence for recurrent mutations and intraclonal heterogeneity.

I. S. Lossos and R. Levy (2000)
Blood 95, 1400-1405
 |  Abstract »  |  Full Text »  |  PDF »

Distribution and pattern of BCL-6 mutations throughout the spectrum of B-cell neoplasia.

D. Capello, U. Vitolo, L. Pasqualucci, S. Quattrone, G. Migliaretti, L. Fassone, C. Ariatti, D. Vivenza, A. Gloghini, C. Pastore, et al. (2000)
Blood 95, 651-659
 |  Abstract »  |  Full Text »  |  PDF »

Lineage-Specific Modulation of Interleukin 4 Signaling by Interferon Regulatory Factor 4.

S. Gupta, M. Jiang, A. Anthony, and A. B. Pernis (1999)
J. Exp. Med. 190, 1837-1848
 |  Abstract »  |  Full Text »  |  PDF »

A Novel BTB/POZ Transcriptional Repressor Protein Interacts With the Fanconi Anemia Group C Protein and PLZF.

M. E. Hoatlin, Y. Zhi, H. Ball, K. Silvey, A. Melnick, S. Stone, S. Arai, N. Hawe, G. Owen, A. Zelent, et al. (1999)
Blood 94, 3737-3747
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Clinicopathogenetic Significance of Chromosomal Abnormalities in Patients With Blastic Peripheral B-Cell Lymphoma.

B. Schlegelberger, T. Zwingers, L. Harder, H. Nowotny, R. Siebert, M. Vesely, H. Bartels, R. Sonnen, G. Hopfinger, A. Nader, et al. (1999)
Blood 94, 3114-3120
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Osteoclast-Derived Zinc Finger (OCZF) Protein With POZ Domain, a Possible Transcriptional Repressor, Is Involved in Osteoclastogenesis.

A. Kukita, T. Kukita, M. Ouchida, H. Maeda, H. Yatsuki, and O. Kohashi (1999)
Blood 94, 1987-1997
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A Role for the GSG Domain in Localizing Sam68 to Novel Nuclear Structures in Cancer Cell Lines.

T. Chen, F.-M. Boisvert, D. P. Bazett-Jones, and S. Richard (1999)
Mol. Biol. Cell 10, 3015-3033
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The Catenin p120ctn Interacts with Kaiso, a Novel BTB/POZ Domain Zinc Finger Transcription Factor.

J. M. Daniel and A. B. Reynolds (1999)
Mol. Cell. Biol. 19, 3614-3623
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Human Immunodeficiency Virus-Associated Hodgkin's Disease Derives From Post-Germinal Center B Cells.

A. Carbone, A. Gloghini, L. M. Larocca, A. Antinori, B. Falini, U. Tirelli, R. Dalla-Favera, and G. Gaidano (1999)
Blood 93, 2319-2326
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trans Repression of the Human Metallothionein IIA Gene Promoter by PZ120, a Novel 120-Kilodalton Zinc Finger Protein.

C.-M. Tang, J. Westling, and E. Seto (1999)
Mol. Cell. Biol. 19, 680-689
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RP58 Associates with Condensed Chromatin and Mediates a Sequence-specific Transcriptional Repression.

K. Aoki, G. Meng, K. Suzuki, T. Takashi, Y. Kameoka, K. Nakahara, R. Ishida, and M. Kasai (1998)
J. Biol. Chem. 273, 26698-26704
 |  Abstract »  |  Full Text »  |  PDF »

Expression Status of BCL-6 and Syndecan-1 Identifies Distinct Histogenetic Subtypes of Hodgkin's Disease.

A. Carbone, A. Gloghini, G. Gaidano, S. Franceschi, D. Capello, H. G. Drexler, B. Falini, and R. Dalla-Favera (1998)
Blood 92, 2220-2228
 |  Abstract »  |  Full Text »  |  PDF »

BCL-6 Gene Mutations in Posttransplantation Lymphoproliferative Disorders Predict Response to Therapy and Clinical Outcome.

E. Cesarman, A. Chadburn, Y.-F. Liu, A. Migliazza, R. Dalla-Favera, and D. M. Knowles (1998)
Blood 92, 2294-2302
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BCL-6 mutations in normal germinal center B cells: Evidence of somatic hypermutation acting outside Ig loci.

L. Pasqualucci, A. Migliazza, N. Fracchiolla, C. William, A. Neri, L. Baldini, R. S. K. Chaganti, U. Klein, R. Kuppers, K. Rajewsky, et al. (1998)
PNAS 95, 11816-11821
 |  Abstract »  |  Full Text »  |  PDF »

The Promyelocytic Leukemia Zinc Finger Protein Affects Myeloid Cell Growth, Differentiation, and Apoptosis.

R. Shaknovich, P. L. Yeyati, S. Ivins, A. Melnick, C. Lempert, S. Waxman, A. Zelent, and J. D. Licht (1998)
Mol. Cell. Biol. 18, 5533-5545
 |  Abstract »  |  Full Text »

Multicolor Spectral Karyotyping Identifies New Recurring Breakpoints and Translocations in Multiple Myeloma.

P. H. Rao, J. C. Cigudosa, Y. Ning, M. J. Calasanz, S. Iida, S. Tagawa, J. Michaeli, B. Klein, R. Dalla-Favera, S. C. Jhanwar, et al. (1998)
Blood 92, 1743-1748
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The Molecular and Phenotypic Profile of Primary Central Nervous System Lymphoma Identifies Distinct Categories of the Disease and Is Consistent With Histogenetic Derivation From Germinal Center-Related B Cells.

L. M. Larocca, D. Capello, A. Rinelli, S. Nori, A. Antinori, A. Gloghini, A. Cingolani, A. Migliazza, G. Saglio, S. Cammilleri-Broet, et al. (1998)
Blood 92, 1011-1019
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BAZF, a Novel Bcl6 Homolog, Functions as a Transcriptional Repressor.

S. Okabe, T. Fukuda, K. Ishibashi, S. Kojima, S. Okada, M. Hatano, M. Ebara, H. Saisho, and T. Tokuhisa (1998)
Mol. Cell. Biol. 18, 4235-4244
 |  Abstract »  |  Full Text »

Antigen receptor signaling induces MAP kinase-mediated phosphorylation and degradation of the BCL-6 transcription factor.

H. Niu, B. H. Ye, and R. Dalla-Favera (1998)
Genes & Dev. 12, 1953-1961
 |  Abstract »  |  Full Text »

Reduced Retinoic Acid-Sensitivities of Nuclear Receptor Corepressor Binding to PML- and PLZF-RARalpha Underlie Molecular Pathogenesis and Treatment of Acute Promyelocytic Leukemia.

F. Guidez, S. Ivins, J. Zhu, M. Soderstrom, S. Waxman, and A. Zelent (1998)
Blood 91, 2634-2642
 |  Abstract »  |  Full Text »  |  PDF »

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