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Science 6 August 1993:
Vol. 261. no. 5122, pp. 754 - 756
DOI: 10.1126/science.261.5122.754
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Articles

Requirement of Salicylic Acid for the Induction of Systemic Acquired Resistance

Thomas Gaffney 1, Leslie Friedrich 1, Bernard Vernooij 1, David Negrotto 1, Gordon Nye 1, Scott Uknes 1, Eric Ward 1, Helmut Kessmann 2, and John Ryals 1

1 Agricultural Biotechnology Research Unit, Ciba-Geigy Corporation, Post Office Box 12257, Research Triangle Park, NC 27709
2 Plant Protection, Ciba-Geigy Limited, CH4002 Basel, Switzerland

It has been proposed that salicylic acid acts as an endogenous signal responsible for inducing systemic acquired resistance in plants. The contribution of salicylic acid to systemic acquired resistance was investigated in transgenic tobacco plants harboring a bacterial gene encoding salicylate hydroxylase, which converts salicylic acid to catechol. Transgenic plants that express salicylate hydroxylase accumulated little or no salicylic acid and were defective in their ability to induce acquired resistance against tobacco mosaic virus. Thus, salicylic acid is essential for the development of systemic acquired resistance in tobacco.

Submitted on April 9, 1993
Accepted on June 4, 1993


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Science. ISSN 0036-8075 (print), 1095-9203 (online)