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Science 30 July 1993: Vol. 261. no. 5121, pp. 615 - 617 DOI: 10.1126/science.8342027
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Articles
Science, Vol 261, Issue 5121, 615-617
Copyright © 1993 by American Association for the Advancement of Science
Functional magnetic resonance imaging of motor cortex: hemispheric asymmetry and handedness
SG Kim,
J Ashe,
K Hendrich,
JM Ellermann,
H Merkle,
K Ugurbil,
and
AP Georgopoulos
Center for Magnetic Resonance Research (CMRR), University of Minnesota Medical School, Minneapolis 55455.
A hemispheric asymmetry in the functional activation of the human motor cortex during contralateral (C) and ipsilateral (I) finger movements, especially in right-handed subjects, was documented with nuclear magnetic resonance imaging at high field strength (4 tesla). Whereas the right motor cortex was activated mostly during contralateral finger movements in both right-handed (C/I mean area of activation = 36.8) and left-handed (C/I = 29.9) subjects, the left motor cortex was activated substantially during ipsilateral movements in left-handed subjects (C/I = 5.4) and even more so in right-handed subjects (C/I = 1.3).
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| Abstract »
| Full Text »
| PDF »
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| Full Text »
| PDF »
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| Abstract »
| Full Text »
| PDF »
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| Abstract »
| Full Text »
| PDF »
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