Science 23 July 1993: Vol. 261. no. 5120, pp. 472 - 475 DOI: 10.1126/science.8332913

Prev | Table of Contents | Next

Articles

Externalization of the Leaderless Cytokine IL-1F6 Occurs in Response to Lipopolysaccharide/ATP Activation of Transduced Bone Marrow Macrophages.

U. Martin, J. Scholler, J. Gurgel, B. Renshaw, J. E. Sims, and C. A. Gabel (2009)
J. Immunol. 183, 4021-4030
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin 1 regulates its own receptors in human endometrial cells via distinct mechanisms.

C. Bellehumeur, J. Blanchet, J.-Y. Fontaine, N. Bourcier, and A. Akoum (2009)
Hum. Reprod. 24, 2193-2204
 |  Abstract »  |  Full Text »  |  PDF »

Early gene expression changes induced by the bacterial superantigen staphylococcal enterotoxin B and its modulation by a proteasome inhibitor.

G. Rajagopalan, A. Y. Tilahun, Y. W. Asmann, and C. S. David (2009)
Physiol Genomics 37, 279-293
 |  Abstract »  |  Full Text »  |  PDF »

Differential requirement for the activation of the inflammasome for processing and release of IL-1{beta} in monocytes and macrophages.

M. G. Netea, C. A. Nold-Petry, M. F. Nold, L. A. B. Joosten, B. Opitz, J. H. M. van der Meer, F. L. van de Veerdonk, G. Ferwerda, B. Heinhuis, I. Devesa, et al. (2009)
Blood 113, 2324-2335
 |  Abstract »  |  Full Text »  |  PDF »

Liver Transcriptome Profiles Associated with Strain-Specific Ehrlichia chaffeensis-Induced Hepatitis in SCID Mice.

K. Miura and Y. Rikihisa (2009)
Infect. Immun. 77, 245-254
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-1 Receptor Type I Signaling Critically Regulates Infarct Healing and Cardiac Remodeling.

M. Bujak, M. Dobaczewski, K. Chatila, L. H. Mendoza, N. Li, A. Reddy, and N. G. Frangogiannis (2008)
Am. J. Pathol. 173, 57-67
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin 1 Signaling Is Regulated by Leukemia Inhibitory Factor (LIF) and Is Aberrant in Lif-/- Mouse Uterus.

A.A Fouladi-Nashta, L Mohamet, J.K Heath, and S.J Kimber (2008)
Biol Reprod 79, 142-153
 |  Abstract »  |  Full Text »  |  PDF »

Osteoimmunology: Interactions of the Bone and Immune System.

J. Lorenzo, M. Horowitz, and Y. Choi (2008)
Endocr. Rev. 29, 403-440
 |  Abstract »  |  Full Text »  |  PDF »

Chorionic Gonadotropin Down-Regulates the Expression of the Decoy Inhibitory Interleukin 1 Receptor Type II in Human Endometrial Epithelial Cells.

C. Herrmann-Lavoie, C. V. Rao, and A. Akoum (2007)
Endocrinology 148, 5377-5384
 |  Abstract »  |  Full Text »  |  PDF »

Stable inhibition of interleukin 1 receptor type II in Ishikawa cells augments secretion of matrix metalloproteinases: possible role in endometriosis pathophysiology.

S Guay and A Akoum (2007)
Reproduction 134, 525-534
 |  Abstract »  |  Full Text »  |  PDF »

Functional Role for I{kappa}BNS in T Cell Cytokine Regulation As Revealed by Targeted Gene Disruption.

M. Touma, V. Antonini, M. Kumar, S. L. Osborn, A. M. Bobenchik, D. B. Keskin, J. E. Connolly, M. J. Grusby, E. L. Reinherz, and L. K. Clayton (2007)
J. Immunol. 179, 1681-1692
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-1beta is the primary initiator of pulmonary inflammation following liver injury in mice.

S. C. Glasgow, S. Ramachandran, T. S. Blackwell, T. Mohanakumar, and W. C. Chapman (2007)
Am J Physiol Lung Cell Mol Physiol 293, L491-L496
 |  Abstract »  |  Full Text »  |  PDF »

Haplotypes of IL1B, IL1RN, IL1R1, and IL1R2 and the Risk of Venous Thrombosis.

R. van Minkelen, M. C.H. de Visser, J. J. Houwing-Duistermaat, H. L. Vos, R. M. Bertina, and F. R. Rosendaal (2007)
Arterioscler Thromb Vasc Biol 27, 1486-1491
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Characterization of Inflammatory Genes in Sentinel and Nonsentinel Nodes in Melanoma.

H. Torisu-Itakura, J. H. Lee, R. P. Scheri, Y. Huynh, X. Ye, R. Essner, and D. L. Morton (2007)
Clin. Cancer Res. 13, 3125-3132
 |  Abstract »  |  Full Text »  |  PDF »

Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6.

Y. Martinez de la Torre, C. Buracchi, E. M. Borroni, J. Dupor, R. Bonecchi, M. Nebuloni, F. Pasqualini, A. Doni, E. Lauri, C. Agostinis, et al. (2007)
PNAS 104, 2319-2324
 |  Abstract »  |  Full Text »  |  PDF »

Gene transfer of a soluble IL-1 type 2 receptor-Ig fusion protein improves cardiac allograft survival in rats.

E. Simeoni, J. Dudler, S. Fleury, J. Li, M. Pagnotta, M. Pascual, L. K. von Segesser, and G. Vassalli (2007)
Eur. J. Cardiothorac. Surg. 31, 222-228
 |  Abstract »  |  Full Text »  |  PDF »

Selective Modulation of Hedgehog/GLI Target Gene Expression by Epidermal Growth Factor Signaling in Human Keratinocytes..

M. Kasper, H. Schnidar, G. W. Neill, M. Hanneder, S. Klingler, L. Blaas, C. Schmid, C. Hauser-Kronberger, G. Regl, M. P. Philpott, et al. (2006)
Mol. Cell. Biol. 26, 6283-6298
 |  Abstract »  |  Full Text »  |  PDF »

The P2X7 Receptor: A Key Player in IL-1 Processing and Release.

D. Ferrari, C. Pizzirani, E. Adinolfi, R. M. Lemoli, A. Curti, M. Idzko, E. Panther, and F. Di Virgilio (2006)
J. Immunol. 176, 3877-3883
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of IL-1 Family Cytokines IL-1{alpha}, IL-1 Receptor Antagonist, and IL-18 by 1,25-Dihydroxyvitamin D3 in Primary Keratinocytes.

J. Kong, S. A. Grando, and Y. C. Li (2006)
J. Immunol. 176, 3780-3787
 |  Abstract »  |  Full Text »  |  PDF »

Chondroprotective drugs in degenerative joint diseases.

G. Verbruggen (2006)
Rheumatology 45, 129-138
 |  Abstract »  |  Full Text »  |  PDF »

FokI Polymorphism, Vitamin D Receptor, and Interleukin-1 Receptor Haplotypes Are Associated with Type 1 Diabetes in the Dalmatian Population.

T. Zemunik, V. Skrabic, V. Boraska, D. Diklic, I. M. Terzic, V. Capkun, M. Peruzovic, and J. Terzic (2005)
J. Mol. Diagn. 7, 600-604
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Uteroglobin-Related Protein 2 (Ugrp2) Gene Expression by the Th2 Cytokines IL-4 and IL-13.

A. Yamada, F. Sheikh, T. Niimi, F. J. DeMayo, A. D. Keegan, R. P. Donnelly, and S. Kimura (2005)
J. Immunol. 175, 5708-5715
 |  Abstract »  |  Full Text »  |  PDF »

The RNA Helicase Lgp2 Inhibits TLR-Independent Sensing of Viral Replication by Retinoic Acid-Inducible Gene-I.

S. Rothenfusser, N. Goutagny, G. DiPerna, M. Gong, B. G. Monks, A. Schoenemeyer, M. Yamamoto, S. Akira, and K. A. Fitzgerald (2005)
J. Immunol. 175, 5260-5268
 |  Abstract »  |  Full Text »  |  PDF »

Systemic inflammation in COPD visualised by gene profiling in peripheral blood neutrophils.

E-J D Oudijk, E H J Nijhuis, M D Zwank, E A van de Graaf, H J Mager, P J Coffer, J-W J Lammers, and L Koenderman (2005)
Thorax 60, 538-544
 |  Abstract »  |  Full Text »  |  PDF »

Increased soluble interleukin-1 receptor type II proteolysis in the endometrium of women with endometriosis.

C. Bellehumeur, T. Collette, R. Maheux, J. Mailloux, M. Villeneuve, and A. Akoum (2005)
Hum. Reprod. 20, 1177-1184
 |  Abstract »  |  Full Text »  |  PDF »

Effect of Hydrodynamics-Based Gene Delivery of Plasmid DNA Encoding Interleukin-1 Receptor Antagonist-Ig for Treatment of Rat Autoimmune Myocarditis: Possible Mechanism for Lymphocytes and Noncardiac Cells.

H. Liu, H. Hanawa, T. Yoshida, R. Elnaggar, M. Hayashi, R. Watanabe, K. Toba, K. Yoshida, H. Chang, Y. Okura, et al. (2005)
Circulation 111, 1593-1600
 |  Abstract »  |  Full Text »  |  PDF »

Role of Interleukin-4 in Regulation of Age-related Inflammatory Changes in the Hippocampus.

Y. Nolan, F. O. Maher, D. S. Martin, R. M. Clarke, M. T. Brady, A. E Bolton, K. H. G. Mills, and M. A. Lynch (2005)
J. Biol. Chem. 280, 9354-9362
 |  Abstract »  |  Full Text »  |  PDF »

Target ablation-induced regulation of macrophage recruitment into the olfactory epithelium of Mip-1{alpha}-/- mice and restoration of function by exogenous MIP-1{alpha}.

K. Kwong, R. A. Vaishnav, Y. Liu, N. Subhedar, A. J. Stromberg, M. L. Getchell, and T. V. Getchell (2004)
Physiol Genomics 20, 73-86
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-{gamma} Inhibits STAT6 Signal Transduction and Gene Expression in Human Airway Epithelial Cells.

N. M. Heller, S. Matsukura, S. N. Georas, M. R. Boothby, P. B. Rothman, C. Stellato, and R. P. Schleimer (2004)
Am. J. Respir. Cell Mol. Biol. 31, 573-582
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of Soluble Cytokine Receptor Generation.

S. J. Levine (2004)
J. Immunol. 173, 5343-5348
 |  Abstract »  |  Full Text »  |  PDF »

The Role of Interleukin-1{beta} in Direct and Toll-Like Receptor 4-Mediated Neutrophil Activation and Survival.

L. R. Prince, L. Allen, E. C. Jones, P. G. Hellewell, S. K. Dower, M. K.B. Whyte, and I. Sabroe (2004)
Am. J. Pathol. 165, 1819-1826
 |  Abstract »  |  Full Text »  |  PDF »

Cell Type-Specific Interleukin-1{beta} Signaling in the CNS.

D. Srinivasan, J.-H. Yen, D. J. Joseph, and W. Friedman (2004)
J. Neurosci. 24, 6482-6488
 |  Abstract »  |  Full Text »  |  PDF »

Tumor cells secreting IL-13 but not IL-13R{alpha}2 fusion protein have reduced tumorigenicity in vivo.

H.-L. Ma, M. J. Whitters, B. A. Jacobson, D. D. Donaldson, M. Collins, and K. Dunussi-Joannopoulos (2004)
Int. Immunol. 16, 1009-1017
 |  Abstract »  |  Full Text »  |  PDF »

{beta}-Arrestin-dependent Constitutive Internalization of the Human Chemokine Decoy Receptor D6.

E. Galliera, V. R. Jala, J. O. Trent, R. Bonecchi, P. Signorelli, R. J. Lefkowitz, A. Mantovani, M. Locati, and B. Haribabu (2004)
J. Biol. Chem. 279, 25590-25597
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-1 Receptor Antagonist Attenuates Airway Hyperresponsiveness Following Exposure to Ozone.

J.-W. Park, C. Taube, C. Swasey, T. Kodama, A. Joetham, A. Balhorn, K. Takeda, N. Miyahara, C. B. Allen, A. Dakhama, et al. (2004)
Am. J. Respir. Cell Mol. Biol. 30, 830-836
 |  Abstract »  |  Full Text »  |  PDF »

TGF-{beta} down-regulates IL-1{alpha}-induced TLR2 expression in murine hepatocytes.

T. Matsumura, H. Hayashi, T. Takii, C. F. Thorn, A. S. Whitehead, J.-i. Inoue, and K. Onozaki (2004)
J. Leukoc. Biol. 75, 1056-1061
 |  Abstract »  |  Full Text »  |  PDF »

Extracellular and intracellular decoys in the tuning of inflammatory cytokines and Toll-like receptors: the new entry TIR8/SIGIRR.

A. Mantovani, M. Locati, N. Polentarutti, A. Vecchi, and C. Garlanda (2004)
J. Leukoc. Biol. 75, 738-742
 |  Abstract »  |  Full Text »  |  PDF »

Identification of potent human anti-IL-1RI antagonist antibodies.

Z. L. Fredericks, C. Forte, I. V. Capuano, H. Zhou, T. Vanden Bos, and P. Carter (2004)
Protein Eng. Des. Sel. 17, 95-106
 |  Abstract »  |  Full Text »  |  PDF »

Shedding of the Type II IL-1 Decoy Receptor Requires a Multifunctional Aminopeptidase, Aminopeptidase Regulator of TNF Receptor Type 1 Shedding.

X. Cui, F. N. Rouhani, F. Hawari, and S. J. Levine (2003)
J. Immunol. 171, 6814-6819
 |  Abstract »  |  Full Text »  |  PDF »

IL-1{beta} Scavenging by the Type II IL-1 Decoy Receptor in Human Neutrophils.

E. Bourke, A. Cassetti, A. Villa, E. Fadlon, F. Colotta, and A. Mantovani (2003)
J. Immunol. 170, 5999-6005
 |  Abstract »  |  Full Text »  |  PDF »

Regulation and Function of the Interleukin 13 Receptor {alpha} 2 During a T Helper Cell Type 2-dominant Immune Response.

M. G. Chiaramonte, M. Mentink-Kane, B. A. Jacobson, A. W. Cheever, M. J. Whitters, M. E.P. Goad, A. Wong, M. Collins, D. D. Donaldson, M. J. Grusby, et al. (2003)
J. Exp. Med. 197, 687-701
 |  Abstract »  |  Full Text »  |  PDF »

Interleukins in Atherosclerosis: Molecular Pathways and Therapeutic Potential.

J. H. Von der Thusen, J. Kuiper, T. J. C. Van Berkel, and E. A. L. Biessen (2003)
Pharmacol. Rev. 55, 133-166
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Scavenging of Inflammatory CC Chemokines by the Promiscuous Putatively Silent Chemokine Receptor D6.

A. M. Fra, M. Locati, K. Otero, M. Sironi, P. Signorelli, M. L. Massardi, M. Gobbi, A. Vecchi, S. Sozzani, and A. Mantovani (2003)
J. Immunol. 170, 2279-2282
 |  Abstract »  |  Full Text »  |  PDF »

Strong Expression of Interleukin-1 Receptor Type I in the Rat Carotid Body.

X. Wang, B.-R. Wang, X.-L. Duan, P. Zhang, Y.-Q. Ding, Y. Jia, X.-Y. Jiao, and G. Ju (2002)
J. Histochem. Cytochem. 50, 1677-1684
 |  Abstract »  |  Full Text »  |  PDF »

High circulating levels of the IL-1 type II decoy receptor in critically ill patients with sepsis: association of high decoy receptor levels with glucocorticoid administration.

B. Muller, G. Peri, A. Doni, A. P. Perruchoud, R. Landmann, F. Pasqualini, and A. Mantovani (2002)
J. Leukoc. Biol. 72, 643-649
 |  Abstract »  |  Full Text »  |  PDF »

IL-1{beta} potentiates heat-activated currents in rat sensory neurons: involvement of IL-1RI, tyrosine kinase, and protein kinase C.

O. OBREJA, P. K. RATHEE, K. S. LIPS, C. DISTLER, and M. KRESS (2002)
FASEB J 16, 1497-1503
 |  Abstract »  |  Full Text »  |  PDF »

Molecular basis of the synergistic production of IL-1 receptor antagonist by human neutrophils stimulated with IL-4 and IL-10.

L. Crepaldi, L. Silveri, F. Calzetti, C. Pinardi, and M. A. Cassatella (2002)
Int. Immunol. 14, 1145-1153
 |  Abstract »  |  Full Text »  |  PDF »

Alterations in membrane-associated CD14 expression and the simultaneous liberation of soluble CD14 fragment in adherent macrophages mediated by a leukocyte carboxyl/aspartate protease.

C.P. Coyne, T. Howell, H. Smodlaka, C. Willetto, B. W. Fenwick, and E. Chenney (2002)
Innate Immunity 8, 273-283
 |  Abstract »  |  PDF »

Critical Role of Signaling Through IL-1 Receptor for Development of Arthritis and Sepsis During Staphylococcus aureus Infection.

O. H. Hultgren, L. Svensson, and A. Tarkowski (2002)
J. Immunol. 168, 5207-5212
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Essential Regions in the Cytoplasmic Tail of Interleukin-1 Receptor Accessory Protein Critical for Interleukin-1 Signaling.

J. Radons, S. Gabler, H. Wesche, C. Korherr, R. Hofmeister, and W. Falk (2002)
J. Biol. Chem. 277, 16456-16463
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Mechanism by Which Interferon-gamma Can Regulate Interleukin (IL)-13 Responses. EVIDENCE FOR INTRACELLULAR STORES OF IL-13 RECEPTOR alpha -2 AND THEIR RAPID MOBILIZATION BY INTERFERON-gamma.

M. O. Daines and G. K. K. Hershey (2002)
J. Biol. Chem. 277, 10387-10393
 |  Abstract »  |  Full Text »  |  PDF »

Abnormal Interleukin-1 Receptor Type II Gene Expression in the Endometrium of Women with Endometriosis.

A. Kharfi, A. Boucher, and A. Akoum (2002)
Biol Reprod 66, 401-406
 |  Abstract »  |  Full Text »  |  PDF »

A polymorphism within the interleukin 1 receptor antagonist (IL-1Ra) gene is associated with ankylosing spondylitis.

F. McGarry, J. Neilly, N. Anderson, R. Sturrock, and M. Field (2001)
Rheumatology 40, 1359-1364
 |  Abstract »  |  Full Text »  |  PDF »

Cytokine Balance in the Lungs of Patients with Acute Respiratory Distress Syndrome.

W. Y. PARK, R. B. GOODMAN, K. P. STEINBERG, J. T. RUZINSKI, F. RADELLA II, D. R. PARK, J. PUGIN, S. J. SKERRETT, L. D. HUDSON, and T. R. MARTIN (2001)
Am. J. Respir. Crit. Care Med. 164, 1896-1903
 |  Abstract »  |  Full Text »  |  PDF »

Selective Activation of p38 Mitogen-Activated Protein Kinase Cascade in Human Neutrophils Stimulated by IL-1{beta}.

K. Suzuki, M. Hino, H. Kutsuna, F. Hato, C. Sakamoto, T. Takahashi, N. Tatsumi, and S. Kitagawa (2001)
J. Immunol. 167, 5940-5947
 |  Abstract »  |  Full Text »  |  PDF »

Systemic anti-inflammatory mediators in COPD: increase in soluble interleukin 1 receptor II during treatment of exacerbations.

M A Dentener, E C Creutzberg, A M W J Schols, A Mantovani, C van`t Veer, W A Buurman, and E F M Wouters (2001)
Thorax 56, 721-726
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional Regulation of Intracellular IL-1 Receptor Antagonist Gene by IL-1{{alpha}} in Primary Mouse Keratinocytes.

E. La and S. M. Fischer (2001)
J. Immunol. 166, 6149-6155
 |  Abstract »  |  Full Text »  |  PDF »

Resolution of pluripotential intermediates in murine hematopoietic differentiation by global complementary DNA amplification from single cells: confirmation of assignments by expression profiling of cytokine receptor transcripts.

F. Billia, M. Barbara, J. McEwen, M. Trevisan, and N. N. Iscove (2001)
Blood 97, 2257-2268
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-1 receptor accessory protein is constitutively expressed in human endometrium throughout the menstrual cycle.

F. Bigonnesse, M. Marois, R. Maheux, and A. Akoum (2001)
Mol. Hum. Reprod. 7, 333-339
 |  Abstract »  |  Full Text »  |  PDF »

Cytokine Pathways and Joint Inflammation in Rheumatoid Arthritis.

E. H.S. Choy and G. S. Panayi (2001)
N. Engl. J. Med. 344, 907-916
 |  Full Text »  |  PDF »

Synthesis of Type II Interleukin-1 Receptors by Human Corneal Epithelial Cells but not by Keratocytes.

C. L. Cubitt, R. N. Lausch, and J. E. Oakes (2001)
Invest. Ophthalmol. Vis. Sci. 42, 701-704
 |  Abstract »  |  Full Text »

CONCISE REVIEW Biological: Interleukin 1 Signal Transduction-- Current Concepts and Relevance to Periodontitis.

J.A. Boch, N. Wara-aswapati, and P.E. Auron (2001)
Journal of Dental Research 80, 400-407
 |  Abstract »  |  PDF »

Decreased Expression of the Decoy Interleukin-1 Receptor Type II in Human Endometriosis.

A. Akoum, C. Jolicoeur, A. Kharfi, and M. Aube (2001)
Am. J. Pathol. 158, 481-489
 |  Abstract »  |  Full Text »  |  PDF »

TNF-{{alpha}}-Converting Enzyme Cleaves the Macrophage Colony-Stimulating Factor Receptor in Macrophages Undergoing Activation.

E. Rovida, A. Paccagnini, M. Del Rosso, J. Peschon, and P. Dello Sbarba (2001)
J. Immunol. 166, 1583-1589
 |  Abstract »  |  Full Text »  |  PDF »

Neutrophil migration stimulates rat intestinal epithelial cell cytokine expression during helminth infection.

A. W. Stadnyk, C. D. Dollard, and A. C. Issekutz (2000)
J. Leukoc. Biol. 68, 821-827
 |  Abstract »  |  Full Text »

Clostridium difficile Toxins Influence Hepatocyte Protein Synthesis Through the Interleukin 1 Receptor.

J. E. Mazuski, E. M. Grossmann, J. G. Norman, W. Denham, N. Panesar, M. J. Shapiro, R. L. Durham, D. L. Kaminski, and W. E. Longo (2000)
Arch Surg 135, 1206-1211
 |  Abstract »  |  Full Text »  |  PDF »

The Membrane Form of the Type II IL-1 Receptor Accounts for Inhibitory Function.

D. Neumann, C. Kollewe, M. U. Martin, and D. Boraschi (2000)
J. Immunol. 165, 3350-3357
 |  Abstract »  |  Full Text »  |  PDF »

Periovulatory and Interleukin (IL)-1--Dependent Reglation of IL-6 in the Immature Rat Ovary: A Specific IL-1 Receptor-Mediated Eicosanoid-Dependent Effect.

K. W. Chung, M. Ando, and E. Y. Adashi (2000)
Reproductive Sciences 7, 301-308
 |  Abstract »  |  PDF »

Induction of Intracellular Interleukin-1 {beta} Signals via Type II Interleukin-1 Receptor in Human Gingival Fibroblasts.

H.-H. Chou, S. Takashiba, H. Maeda, K. Naruishi, F. Nishimura, H. Arai, H.-k. Lu, and Y. Murayama (2000)
Journal of Dental Research 79, 1683-1688
 |  Abstract »  |  PDF »

The Interleukin-1 Receptor/Toll-like Receptor Superfamily: Signal Transduction During Inflammation and Host Defense.

L. A. J. O'Neill (2000)
Sci. STKE 2000, re1
 |  Abstract »  |  Full Text »  |  PDF »

Proinflammatory Cytokines.

C. A. Dinarello (2000)
Chest 118, 503-508
 |  Abstract »  |  Full Text »  |  PDF »

IL-4 production by human polymorphonuclear neutrophils.

E. Brandt, G. Woerly, A. B. Younes, S. Loiseau, and M. Capron (2000)
J. Leukoc. Biol. 68, 125-130
 |  Abstract »  |  Full Text »

Tumor Necrosis Factor Induces Resistance of Macrophages to Legionella pneumophila Infection.

S. L. McHugh, C. A. Newton, Y. Yamamoto, T. W. Klein, and H. Friedman (2000)
Experimental Biology and Medicine 224, 191-196
 |  Abstract »  |  Full Text »

Endogenous brain IL-1 mediates LPS-induced anorexia and hypothalamic cytokine expression.

S. Laye, G. Gheusi, S. Cremona, C. Combe, K. Kelley, R. Dantzer, and P. Parnet (2000)
Am J Physiol Regulatory Integrative Comp Physiol 279, R93-R98
 |  Abstract »  |  Full Text »  |  PDF »

Molecular mechanisms of glucocorticoid action: what is important?.

R. Newton (2000)
Thorax 55, 603-613
 |  Full Text »

Interleukin-4 inhibits interleukin-11 production by rheumatoid synovial cells.

H. Taki, E. Sugiyama, A. Kuroda, T. Mino, and M. Kobayashi (2000)
Rheumatology 39, 728-731
 |  Abstract »  |  Full Text »  |  PDF »

Functional Analysis of the Domain Structure of Tumor Necrosis Factor-alpha Converting Enzyme.

P. Reddy, J. L. Slack, R. Davis, D. P. Cerretti, C. J. Kozlosky, R. A. Blanton, D. Shows, J. J. Peschon, and R. A. Black (2000)
J. Biol. Chem. 275, 14608-14614
 |  Abstract »  |  Full Text »  |  PDF »

Cellular Differentiation Causes a Selective Down-regulation of Interleukin (IL)-1beta -mediated NF-kappa B Activation and IL-8 Gene Expression in Intestinal Epithelial Cells.

U. Bocker, A. Schottelius, J. M. Watson, L. Holt, L. L. Licato, D. A. Brenner, R. B. Sartor, and C. Jobin (2000)
J. Biol. Chem. 275, 12207-12213
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Functional IL-8 Receptors by IL-4 and IL-13 in Human Monocytes.

R. Bonecchi, F. Facchetti, S. Dusi, W. Luini, D. Lissandrini, M. Simmelink, M. Locati, S. Bernasconi, P. Allavena, E. Brandt, et al. (2000)
J. Immunol. 164, 3862-3869
 |  Abstract »  |  Full Text »  |  PDF »

Serum Withdrawal-Induced Apoptosis in Thyroid Cells Is Caused by Loss of Fibronectin-Integrin Interaction.

T. Di Matola, F. Mueller, G. Fenzi, G. Rossi, M. Bifulco, L. A. Marzano, and M. Vitale (2000)
J. Clin. Endocrinol. Metab. 85, 1188-1193
 |  Abstract »  |  Full Text »

How Do Glucocorticoids Influence Stress Responses? Integrating Permissive, Suppressive, Stimulatory, and Preparative Actions.

R. M. Sapolsky, L. M. Romero, and A. U. Munck (2000)
Endocr. Rev. 21, 55-89
 |  Abstract »  |  Full Text »

Development of Chronic Inflammatory Arthropathy Resembling Rheumatoid Arthritis in Interleukin 1 Receptor Antagonist-Deficient Mice.

R. Horai, S. Saijo, H. Tanioka, S. Nakae, K. Sudo, A. Okahara, T. Ikuse, M. Asano, and Y. Iwakura (2000)
J. Exp. Med. 191, 313-320
 |  Abstract »  |  Full Text »  |  PDF »

Four New Members Expand the Interleukin-1 Superfamily.

D. E. Smith, B. R. Renshaw, R. R. Ketchem, M. Kubin, K. E. Garka, and J. E. Sims (2000)
J. Biol. Chem. 275, 1169-1175
 |  Abstract »  |  Full Text »  |  PDF »

Cloning and Expression of a Short Fas Ligand: A New Alternatively Spliced Product of the Mouse Fas Ligand Gene.

E. Ayroldi, F. D'Adamio, O. Zollo, M. Agostini, R. Moraca, L. Cannarile, G. Migliorati, D. V. Delfino, and C. Riccardi (1999)
Blood 94, 3456-3467
 |  Abstract »  |  Full Text »  |  PDF »

Adenoviral Vector-Mediated Overexpression of IL-4 in the Knee Joint of Mice with Collagen-Induced Arthritis Prevents Cartilage Destruction.

E. Lubberts, L. A. B. Joosten, L. van den Bersselaar, M. M. A. Helsen, A. C. Bakker, J. B. J. van Meurs, F. L. Graham, C. D. Richards, and W. B. van den Berg (1999)
J. Immunol. 163, 4546-4556
 |  Abstract »  |  Full Text »  |  PDF »

IL-1 and TNF Receptor-Deficient Mice Show Decreased Inflammation in an Immune Complex Model of Uveitis.

B. E. Brito, L. M. O’Rourke, Y. Pan, J. Anglin, S. R. Planck, and J. T. Rosenbaum (1999)
Invest. Ophthalmol. Vis. Sci. 40, 2583-2589
 |  Abstract »  |  Full Text »  |  PDF »

Corticosteroids in Acute Respiratory Failure.

M. A. JANTZ and S. A. SAHN (1999)
Am. J. Respir. Crit. Care Med. 160, 1079-1100
 |  Full Text »

Up-Regulation of CCR2 Chemokine Receptor Expression and Increased Susceptibility to the Multitropic HIV Strain 89.6 in Monocytes Exposed to Glucocorticoid Hormones.

G. Penton-Rol, M. Cota, N. Polentarutti, W. Luini, S. Bernasconi, A. Borsatti, A. Sica, G. J. LaRosa, S. Sozzani, G. Poli, et al. (1999)
J. Immunol. 163, 3524-3529
 |  Abstract »  |  Full Text »  |  PDF »

Interferons inhibit activation of STAT6 by interleukin 4 in human monocytes by inducing SOCS-1 gene expression.

H. L. Dickensheets, C. Venkataraman, U. Schindler, and R. P. Donnelly (1999)
PNAS 96, 10800-10805
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin 15 Induces Endothelial Hyaluronan Expression in Vitro and Promotes Activated T Cell Extravasation through a Cd44-Dependent Pathway in Vivo.

P. Estess, A. Nandi, M. Mohamadzadeh, and M. H. Siegelman (1999)
J. Exp. Med. 190, 9-20
 |  Abstract »  |  Full Text »  |  PDF »

Ovarian Interleukin-1 Receptor Antagonist in Rats: Gene Expression, Cellular Localization, Cyclic Variation, and Hormonal Regulation of a Potential Determinant of Interleukin-1 Action.

S. Kol, B. W. Donesky, K. Ruutiainen-Altman, I. Ben-Shlomo, M. Irahara, M. Ando, R. M. Rohan, and E. Y. Adashi (1999)
Biol Reprod 61, 274-282
 |  Abstract »  |  Full Text »

Extracellular Regulation of Interleukin (IL)-1beta through Lung Epithelial Cells and Defective IL-1 Type II Receptor Expression.

K. R. Coulter, M. D. Wewers, M. P. Lowe, and D. L. Knoell (1999)
Am. J. Respir. Cell Mol. Biol. 20, 964-975
 |  Abstract »  |  Full Text »

Endotoxin-Stimulated Monocytes Release Multiple Forms of IL-1{beta}, Including a ProIL-1{beta} Form Whose Detection Is Affected by Export.

M. D. Wewers2, A. V. Winnard, and H. A. Dare (1999)
J. Immunol. 162, 4858-4863
 |  Abstract »  |  Full Text »  |  PDF »

Middle Ear Fluid Cytokine and Inflammatory Cell Kinetics in the Chinchilla Otitis Media Model.

K. Sato, C. L. Liebeler, M. K. Quartey, C. T. Le, and G. S. Giebink (1999)
Infect. Immun. 67, 1943-1946
 |  Abstract »  |  Full Text »  |  PDF »

Augmentation of Type I IL-1 Receptor Expression and IL-1 Signaling by IL-6 and Glucocorticoid in Murine Hepatocytes.

A. Ito, T. Takii, T. Matsumura, and K. Onozaki (1999)
J. Immunol. 162, 4260-4265
 |  Abstract »  |  Full Text »  |  PDF »

The Interleukin-1 Type 2 Receptor Gene Displays Immediate Early Gene Responsiveness in Glucocorticoid-stimulated Human Epidermal Keratinocytes.

W. J. Lukiw, J. Martinez, R. P. Pelaez, and N. G. Bazan (1999)
J. Biol. Chem. 274, 8630-8638
 |  Abstract »  |  Full Text »  |  PDF »

Bacterial Lipopolysaccharide Causes Rapid Shedding, Followed by Inhibition of mRNA Expression, of the IL-1 Type II Receptor, with Concomitant Up-Regulation of the Type I Receptor and Induction of Incompletely Spliced Transcripts.

G. Penton-Rol, S. Orlando, N. Polentarutti, S. Bernasconi, M. Muzio, M. Introna, and A. Mantovani (1999)
J. Immunol. 162, 2931-2938
 |  Abstract »  |  Full Text »  |  PDF »

Cytokines - killers in the brain?.

N. J Rothwell (1999)
J. Physiol. 514, 3-17
 |  Abstract »  |  Full Text »  |  PDF »

The Type II IL-1 Receptor Interacts with the IL-1 Receptor Accessory Protein: A Novel Mechanism of Regulation of IL-1 Responsiveness.

D. Lang, J. Knop, H. Wesche, U. Raffetseder, R. Kurrle, D. Boraschi, and M. U. Martin (1998)
J. Immunol. 161, 6871-6877
 |  Abstract »  |  Full Text »  |  PDF »

To Advertise   |   Find Products