Science 9 July 1993: Vol. 261. no. 5118, pp. 221 - 224 DOI: 10.1126/science.7687074

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Articles

BK channels in cardiovascular disease: a complex story of channel dysregulation.

N. J. Rusch (2009)
Am J Physiol Heart Circ Physiol 297, H1580-H1582
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Intersubunit Coupling in the Pore of BK Channels.

Y. Wu, Y. Xiong, S. Wang, H. Yi, H. Li, N. Pan, F. T. Horrigan, Y. Wu, and J. Ding (2009)
J. Biol. Chem. 284, 23353-23363
 |  Abstract »  |  Full Text »  |  PDF »

Bovine and Mouse SLO3 K+ Channels: EVOLUTIONARY DIVERGENCE POINTS TO AN RCK1 REGION OF CRITICAL FUNCTION.

C. M. Santi, A. Butler, J. Kuhn, A. Wei, and L. Salkoff (2009)
J. Biol. Chem. 284, 21589-21598
 |  Abstract »  |  Full Text »  |  PDF »

Bimane Fluorescence Scanning Suggests Secondary Structure near the S3-S4 Linker of BK Channels.

N. P. Semenova, K. Abarca-Heidemann, E. Loranc, and B. S. Rothberg (2009)
J. Biol. Chem. 284, 10684-10693
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of BKCa Channel Gating by Endogenous Signaling Molecules.

S. Hou, S. H. Heinemann, and T. Hoshi (2009)
Physiology 24, 26-35
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Measuring the Influence of the BKCa {beta}1 Subunit on Ca2+ Binding to the BKCa Channel.

T.-B. Sweet and D. H. Cox (2009)
J. Gen. Physiol. 133, 139-150
 |  Abstract »  |  Full Text »  |  PDF »

Palmitoylation gates phosphorylation-dependent regulation of BK potassium channels.

L. Tian, O. Jeffries, H. McClafferty, A. Molyvdas, I. C. M. Rowe, F. Saleem, L. Chen, J. Greaves, L. H. Chamberlain, H.-G. Knaus, et al. (2008)
PNAS 105, 21006-21011
 |  Abstract »  |  Full Text »  |  PDF »

Measurements of the BKCa Channel's High-Affinity Ca2+ Binding Constants: Effects of Membrane Voltage.

T.-B. Sweet and D. H. Cox (2008)
J. Gen. Physiol. 132, 491-505
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Return of the Electric Binding Site.

B. S. Rothberg (2008)
J. Gen. Physiol. 132, 487-489
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Locations of the {beta}1 transmembrane helices in the BK potassium channel.

G. Liu, S. I. Zakharov, L. Yang, R. S. Wu, S.-X. Deng, D. W. Landry, A. Karlin, and S. O. Marx (2008)
PNAS 105, 10727-10732
 |  Abstract »  |  Full Text »  |  PDF »

Species-specific Differences among KCNMB3 BK {beta}3 Auxiliary Subunits: Some {beta}3 N-terminal Variants May Be Primate-specific Subunits.

X. Zeng, X.-M. Xia, and C. J. Lingle (2008)
J. Gen. Physiol. 132, 115-129
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An Extracellular Cu2+ Binding Site in the Voltage Sensor of BK and Shaker Potassium Channels.

Z. Ma, K. Y. Wong, and F. T. Horrigan (2008)
J. Gen. Physiol. 131, 483-502
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Mg2+-dependent Regulation of BK Channels: Importance of Electrostatics.

C. J. Lingle (2007)
J. Gen. Physiol. 131, 5-11
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Mg2+ Enhances Voltage Sensor/Gate Coupling in BK Channels.

F. T. Horrigan and Z. Ma (2007)
J. Gen. Physiol. 131, 13-32
 |  Abstract »  |  Full Text »  |  PDF »

Ca2+ dependence of flow-stimulated K secretion in the mammalian cortical collecting duct.

W. Liu, T. Morimoto, C. Woda, T. R. Kleyman, and L. M. Satlin (2007)
Am J Physiol Renal Physiol 293, F227-F235
 |  Abstract »  |  Full Text »  |  PDF »

Interaction Sites between the Slo1 Pore and the NH2 Terminus of the beta2 Subunit, Probed with a Three-residue Sensor.

H. Li, J. Yao, X. Tong, Z. Guo, Y. Wu, L. Sun, N. Pan, H. Wu, T. Xu, and J. Ding (2007)
J. Biol. Chem. 282, 17720-17728
 |  Abstract »  |  Full Text »  |  PDF »

Stimulation of Ca2+-Gated Cl- Currents by the Calcium-Dependent K+ Channel Modulators NS1619 [1,3-Dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-2H-benzimidazol-2-one] and Isopimaric Acid.

S. N. Saleh, J. E. Angermann, W. R. Sones, N. Leblanc, and I. A. Greenwood (2007)
J. Pharmacol. Exp. Ther. 321, 1075-1084
 |  Abstract »  |  Full Text »  |  PDF »

Activation by Zonisamide, a Newer Antiepileptic Drug, of Large-Conductance Calcium-Activated Potassium Channel in Differentiated Hippocampal Neuron-Derived H19-7 Cells.

C.-W. Huang, C.-C. Huang, and S.-N. Wu (2007)
J. Pharmacol. Exp. Ther. 321, 98-106
 |  Abstract »  |  Full Text »  |  PDF »

A Role for the S0 Transmembrane Segment in Voltage-dependent Gating of BK Channels.

O. M. Koval, Y. Fan, and B. S. Rothberg (2007)
J. Gen. Physiol. 129, 209-220
 |  Abstract »  |  Full Text »  |  PDF »

An S6 Mutation in BK Channels Reveals {beta}1 Subunit Effects on Intrinsic and Voltage-dependent Gating.

B. Wang and R. Brenner (2006)
J. Gen. Physiol. 128, 731-744
 |  Abstract »  |  Full Text »  |  PDF »

A Limited Access Compartment between the Pore Domain and Cytosolic Domain of the BK Channel..

Z. Zhang, Y. Zhou, J.-P. Ding, X.-M. Xia, and C. J. Lingle (2006)
J. Neurosci. 26, 11833-11843
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of cation transport in the distal nephron by mechanical forces.

L. M. Satlin, M. D. Carattino, W. Liu, and T. R. Kleyman (2006)
Am J Physiol Renal Physiol 291, F923-F931
 |  Abstract »  |  Full Text »  |  PDF »

State-dependent Block of BK Channels by Synthesized Shaker Ball Peptides.

W. Li and R. W. Aldrich (2006)
J. Gen. Physiol. 128, 423-441
 |  Abstract »  |  Full Text »  |  PDF »

A Tail of Multiple Calcium-sensing Domains.

L. Salkoff (2006)
J. Gen. Physiol. 128, 387-388
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Intra- and Intersubunit Cooperativity in Activation of BK Channels by Ca2+.

X. Qian, X. Niu, and K. L. Magleby (2006)
J. Gen. Physiol. 128, 389-404
 |  Abstract »  |  Full Text »  |  PDF »

State-independent Block of BK Channels by an Intracellular Quaternary Ammonium.

C. M. Wilkens and R. W. Aldrich (2006)
J. Gen. Physiol. 128, 347-364
 |  Abstract »  |  Full Text »  |  PDF »

pH-regulated Slo3 K+ Channels: Properties of Unitary Currents.

X. Zhang, X. Zeng, X.-M. Xia, and C. J. Lingle (2006)
J. Gen. Physiol. 128, 301-315
 |  Abstract »  |  Full Text »  |  PDF »

Slo3 K+ Channels: Voltage and pH Dependence of Macroscopic Currents.

X. Zhang, X. Zeng, and C. J. Lingle (2006)
J. Gen. Physiol. 128, 317-336
 |  Abstract »  |  Full Text »  |  PDF »

Opposite regulation of Slick and Slack K+ channels by neuromodulators..

C. M. Santi, G. Ferreira, B. Yang, V.-R. Gazula, A. Butler, A. Wei, L. K. Kaczmarek, and L. Salkoff (2006)
J. Neurosci. 26, 5059-5068
 |  Abstract »  |  Full Text »  |  PDF »

Defining the BK channel domains required for beta1-subunit modulation.

J. P. Morrow, S. I. Zakharov, G. Liu, L. Yang, A. J. Sok, and S. O. Marx (2006)
PNAS 103, 5096-5101
 |  Abstract »  |  Full Text »  |  PDF »

Role of Charged Residues in the S1-S4 Voltage Sensor of BK Channels.

Z. Ma, X. J. Lou, and F. T. Horrigan (2006)
J. Gen. Physiol. 127, 309-328
 |  Abstract »  |  Full Text »  |  PDF »

Direct Observation of a Preinactivated, Open State in BK Channels with {beta}2 Subunits.

G. R. Benzinger, X.-M. Xia, and C. J. Lingle (2006)
J. Gen. Physiol. 127, 119-131
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Effects of Multiple Metal Binding Sites on Calcium and Magnesium-dependent Activation of BK Channels.

L. Hu, H. Yang, J. Shi, and J. Cui (2005)
J. Gen. Physiol. 127, 35-50
 |  Abstract »  |  Full Text »  |  PDF »

A cysteine-rich motif confers hypoxia sensitivity to mammalian large conductance voltage- and Ca-activated K (BK) channel {alpha}-subunits.

C. E. McCartney, H. McClafferty, J.-M. Huibant, E. G. Rowan, M. J. Shipston, and I. C. M. Rowe (2005)
PNAS 102, 17870-17876
 |  Abstract »  |  Full Text »  |  PDF »

Generation of Functional Fluorescent BK Channels by Random Insertion of GFP Variants.

T. Giraldez, T. E. Hughes, and F. J. Sigworth (2005)
J. Gen. Physiol. 126, 429-438
 |  Abstract »  |  Full Text »  |  PDF »

Cardioprotective effects of estradiol include the activation of large-conductance Ca2+-activated K+ channels in cardiac mitochondria.

S. Ohya, Y. Kuwata, K. Sakamoto, K. Muraki, and Y. Imaizumi (2005)
Am J Physiol Heart Circ Physiol 289, H1635-H1642
 |  Abstract »  |  Full Text »  |  PDF »

Functionally Diverse Complement of Large Conductance Calcium- and Voltage-activated Potassium Channel (BK) {alpha}-Subunits Generated from a Single Site of Splicing.

L. Chen, L. Tian, S. H.-F. MacDonald, H. McClafferty, M. S. L. Hammond, J.-M. Huibant, P. Ruth, H.-G. Knaus, and M. J. Shipston (2005)
J. Biol. Chem. 280, 33599-33609
 |  Abstract »  |  Full Text »  |  PDF »

Gating and Ionic Currents Reveal How the BKCa Channel's Ca2+ Sensitivity Is Enhanced by its {beta}1 Subunit.

L. Bao and D. H. Cox (2005)
J. Gen. Physiol. 126, 393-412
 |  Abstract »  |  Full Text »  |  PDF »

Activation of the BK (SLO1) Potassium Channel by Mallotoxin.

S. I. Zakharov, J. P. Morrow, G. Liu, L. Yang, and S. O. Marx (2005)
J. Biol. Chem. 280, 30882-30887
 |  Abstract »  |  Full Text »  |  PDF »

The NH2 Terminus of RCK1 Domain Regulates Ca2+-dependent BKCa Channel Gating.

G. Krishnamoorthy, J. Shi, D. Sept, and J. Cui (2005)
J. Gen. Physiol. 126, 227-241
 |  Abstract »  |  Full Text »  |  PDF »

Ca2+-activated K+ channel-associated phosphatase and kinase activities during development.

M. T. Lin, L. D. Longo, W. J. Pearce, and D. A. Hessinger (2005)
Am J Physiol Heart Circ Physiol 289, H414-H425
 |  Abstract »  |  Full Text »  |  PDF »

Properties of BKCa Channels in Oral Keratinocytes.

D.-B. Shieh, S.-R. Yang, X.-Y. Shi, Y.-N. Wu, and S.-N. Wu (2005)
Journal of Dental Research 84, 468-473
 |  Abstract »  |  Full Text »  |  PDF »

Syntaxin-1A Binds to and Modulates the Slo Calcium-Activated Potassium Channel via an Interaction That Excludes Syntaxin Binding to Calcium Channels.

S. M. Cibulsky, H. Fei, and I. B. Levitan (2005)
J Neurophysiol 93, 1393-1405
 |  Abstract »  |  Full Text »  |  PDF »

Delayed expression of large conductance K+ channels reshaping agonist-induced currents in mouse pancreatic acinar cells.

T. Oshiro, H. Takahashi, A. Ohsaga, S. Ebihara, H. Sasaki, and Y. Maruyama (2005)
J. Physiol. 563, 379-391
 |  Abstract »  |  Full Text »  |  PDF »

Identification and Functional Characterization of Ankyrin-Repeat Family Protein ANKRA as a Protein Interacting with BKCa Channel.

H.-H. Lim and C.-S. Park (2005)
Mol. Biol. Cell 16, 1013-1025
 |  Abstract »  |  Full Text »  |  PDF »

Divalent Cation Sensitivity of BK Channel Activation Supports the Existence of Three Distinct Binding Sites.

X.-H. Zeng, X.-M. Xia, and C. J. Lingle (2005)
J. Gen. Physiol. 125, 273-286
 |  Abstract »  |  Full Text »  |  PDF »

Cysteine Modification Alters Voltage- and Ca2+-dependent Gating of Large Conductance (BK) Potassium Channels.

G. Zhang and F. T. Horrigan (2005)
J. Gen. Physiol. 125, 213-236
 |  Abstract »  |  Full Text »  |  PDF »

The Appearance of a Protein Kinase A-regulated Splice Isoform of slo Is Associated with the Maturation of Neurons That Control Reproductive Behavior.

Y. Zhang, W. J. Joiner, A. Bhattacharjee, F. Rassendren, N. S. Magoski, and L. K. Kaczmarek (2004)
J. Biol. Chem. 279, 52324-52330
 |  Abstract »  |  Full Text »  |  PDF »

Distinct stoichiometry of BKCa channel tetramer phosphorylation specifies channel activation and inhibition by cAMP-dependent protein kinase.

L. Tian, L. S. Coghill, H. McClafferty, S. H.-F. MacDonald, F. A. Antoni, P. Ruth, H.-G. Knaus, and M. J. Shipston (2004)
PNAS 101, 11897-11902
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of K+ Flow by a Ring of Negative Charges in the Outer Pore of BKCa Channels. Part I: Aspartate 292 modulates K+ Conduction by External Surface Charge Effect.

T. Haug, D. Sigg, S. Ciani, L. Toro, E. Stefani, and R. Olcese (2004)
J. Gen. Physiol. 124, 173-184
 |  Abstract »  |  Full Text »  |  PDF »

Unique Inner Pore Properties of BK Channels Revealed by Quaternary Ammonium Block.

W. Li and R. W. Aldrich (2004)
J. Gen. Physiol. 124, 43-57
 |  Abstract »  |  Full Text »  |  PDF »

Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency.

M. Sausbier, H. Hu, C. Arntz, S. Feil, S. Kamm, H. Adelsberger, U. Sausbier, C. A. Sailer, R. Feil, F. Hofmann, et al. (2004)
PNAS 101, 9474-9478
 |  Abstract »  |  Full Text »  |  PDF »

Ligand-Dependent Activation of Slo Family Channels Is Defined by Interchangeable Cytosolic Domains.

X.-M. Xia, X. Zhang, and C. J. Lingle (2004)
J. Neurosci. 24, 5585-5591
 |  Abstract »  |  Full Text »  |  PDF »

Mapping the BKCa Channel's "Ca2+ Bowl": Side-chains Essential for Ca2+ Sensing.

L. Bao, C. Kaldany, E. C. Holmstrand, and D. H. Cox (2004)
J. Gen. Physiol. 123, 475-489
 |  Abstract »  |  Full Text »  |  PDF »

Allosteric Modulation of Ion Channels: The Case of Maxi-K.

B. S. Rothberg (2004)
Sci. STKE 2004, pe16
 |  Abstract »  |  Full Text »  |  PDF »

Ontogeny of flow-stimulated potassium secretion in rabbit cortical collecting duct: functional and molecular aspects.

C. B. Woda, N. Miyawaki, S. Ramalakshmi, M. Ramkumar, R. Rojas, B. Zavilowitz, T. R. Kleyman, and L. M. Satlin (2003)
Am J Physiol Renal Physiol 285, F629-F639
 |  Abstract »  |  Full Text »  |  PDF »

Participation of the S4 voltage sensor in the Mg2+-dependent activation of large conductance (BK) K+ channels.

L. Hu, J. Shi, Z. Ma, G. Krishnamoorthy, F. Sieling, G. Zhang, F. T. Horrigan, and J. Cui (2003)
PNAS 100, 10488-10493
 |  Abstract »  |  Full Text »  |  PDF »

{beta}1 subunits facilitate gating of BK channels by acting through the Ca2+, but not the Mg2+, activating mechanisms.

X. Qian and K. L. Magleby (2003)
PNAS 100, 10061-10066
 |  Abstract »  |  Full Text »  |  PDF »

Contribution of BK Ca2+-Activated K+ Channels to Auditory Neurotransmission in the Guinea Pig Cochlea.

L. J. Skinner, V. Enee, M. Beurg, H. H. Jung, A. F. Ryan, A. Hafidi, J.-M. Aran, and D. Dulon (2003)
J Neurophysiol 90, 320-332
 |  Abstract »  |  Full Text »  |  PDF »

Ethanol sensitivity of BKCa channels from arterial smooth muscle does not require the presence of the beta 1-subunit.

A. M. Dopico (2003)
Am J Physiol Cell Physiol 284, C1468-C1480
 |  Abstract »  |  Full Text »  |  PDF »

Effect of Phosphatidylserine on Unitary Conductance and Ba2+ Block of the BK Ca2+-activated K+ Channel: Re-examination of the Surface Charge Hypothesis.

J. B. Park, H. J. Kim, P. D. Ryu, and E. Moczydlowski (2003)
J. Gen. Physiol. 121, 375-398
 |  Abstract »  |  Full Text »  |  PDF »

Variation in Large-Conductance, Calcium-Activated Potassium Channels from Hair Cells Along the Chicken Basilar Papilla.

R K Duncan and P A Fuchs (2003)
J. Physiol. 547, 357-371
 |  Abstract »  |  Full Text »  |  PDF »

Leucine Zipper Domain Targets cAMP-dependent Protein Kinase to Mammalian BK Channels.

L. Tian, L. S. Coghill, S. H.-F. MacDonald, D. L. Armstrong, and M. J. Shipston (2003)
J. Biol. Chem. 278, 8669-8677
 |  Abstract »  |  Full Text »  |  PDF »

Gating Mechanism of BK (Slo1) Channels: So Near, Yet So Far.

K. L. Magleby (2003)
J. Gen. Physiol. 121, 81-96
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Molecular identification of Ca2+-activated K+ channels in parotid acinar cells.

K. Nehrke, C. C. Quinn, and T. Begenisich (2003)
Am J Physiol Cell Physiol 284, C535-C546
 |  Abstract »  |  Full Text »  |  PDF »

The Cytoplasmic Tail of Large Conductance, Voltage- and Ca2+-activated K+ (MaxiK) Channel Is Necessary for Its Cell Surface Expression.

S.-X. Wang, M. Ikeda, and W. B. Guggino (2003)
J. Biol. Chem. 278, 2713-2722
 |  Abstract »  |  Full Text »  |  PDF »

Slo1 Tail Domains, but Not the Ca2+ Bowl, Are Required for the {beta}1 Subunit to Increase the Apparent Ca2+ Sensitivity of BK Channels.

X. Qian, C. M. Nimigean, X. Niu, B. L. Moss, and K. L. Magleby (2002)
J. Gen. Physiol. 120, 829-843
 |  Abstract »  |  Full Text »  |  PDF »

Coupling between Voltage Sensor Activation, Ca2+ Binding and Channel Opening in Large Conductance (BK) Potassium Channels.

F. T. Horrigan and R. W. Aldrich (2002)
J. Gen. Physiol. 120, 267-305
 |  Abstract »  |  Full Text »  |  PDF »

Setting the Stage for Molecular Dissection of the Regulatory Components of BK Channels.

C. J. Lingle (2002)
J. Gen. Physiol. 120, 261-265
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Elimination of the BKCa Channel's High-Affinity Ca2+ Sensitivity.

L. Bao, A. M. Rapin, E. C. Holmstrand, and D. H. Cox (2002)
J. Gen. Physiol. 120, 173-189
 |  Abstract »  |  Full Text »  |  PDF »

Interacting Effects of N-terminal Variation and Strex Exon Splicing on slo Potassium Channel Regulation by Calcium, Phosphorylation, and Oxidation.

C. Erxleben, A. L. Everhart, C. Romeo, H. Florance, M. B. Bauer, D. A. Alcorta, S. Rossie, M. J. Shipston, and D. L. Armstrong (2002)
J. Biol. Chem. 277, 27045-27052
 |  Abstract »  |  Full Text »  |  PDF »

Expression pattern and functional characteristics of two novel splice variants of the two-pore-domain potassium channel TREK-2.

W. Gu, G. Schlichthorl, J. R Hirsch, H. Engels, C. Karschin, A. Karschin, C. Derst, O. K Steinlein, and J. Daut (2002)
J. Physiol. 539, 657-668
 |  Abstract »  |  Full Text »  |  PDF »

Consequences of the Stoichiometry of Slo1alpha and Auxiliary beta Subunits on Functional Properties of Large-Conductance Ca2+-Activated K+ Channels.

Y.-W. Wang, J. P. Ding, X.-M. Xia, and C. J. Lingle (2002)
J. Neurosci. 22, 1550-1561
 |  Abstract »  |  Full Text »  |  PDF »

Cloning and Characterization of Glioma BK, a Novel BK Channel Isoform Highly Expressed in Human Glioma Cells.

X. Liu, Y. Chang, P. H. Reinhart, and H. Sontheimer (2002)
J. Neurosci. 22, 1840-1849
 |  Abstract »  |  Full Text »  |  PDF »

Opposite Actions of Brain-Derived Neurotrophic Factor and Neurotrophin-3 on Firing Features and Ion Channel Composition of Murine Spiral Ganglion Neurons.

C. L. Adamson, M. A. Reid, and R. L. Davis (2002)
J. Neurosci. 22, 1385-1396
 |  Abstract »  |  Full Text »  |  PDF »

Gating and Conductance Properties of Bk Channels Are Modulated by the S9-S10 Tail Domain of the {alpha} Subunit: A Study of Mslo1 and Mslo3 Wild-Type and Chimeric Channels.

B. L. Moss and K. L. Magleby (2001)
J. Gen. Physiol. 118, 711-734
 |  Abstract »  |  Full Text »  |  PDF »

Alternative splicing determines sensitivity of murine calcium-activated potassium channels to glucocorticoids.

L. Tian, M. S L Hammond, H. Florance, F. A Antoni, and M. J Shipston (2001)
J. Physiol. 537, 57-68
 |  Abstract »  |  Full Text »  |  PDF »

A Molecular Switch for Specific Stimulation of the BKCa Channel by cGMP and cAMP Kinase.

X.-B. Zhou, C. Arntz, S. Kamm, K. Motejlek, U. Sausbier, G.-X. Wang, P. Ruth, and M. Korth (2001)
J. Biol. Chem. 276, 43239-43245
 |  Abstract »  |  Full Text »  |  PDF »

NMR Structure of the "Ball-and-chain" Domain of KCNMB2, the beta 2-Subunit of Large Conductance Ca2+- and Voltage-activated Potassium Channels.

D. Bentrop, M. Beyermann, R. Wissmann, and B. Fakler (2001)
J. Biol. Chem. 276, 42116-42121
 |  Abstract »  |  Full Text »  |  PDF »

Intracellular Mg2+ Enhances the Function of Bk-Type Ca2+-Activated K+ Channels.

J. Shi and J. Cui (2001)
J. Gen. Physiol. 118, 589-606
 |  Abstract »  |  Full Text »  |  PDF »

Allosteric Regulation of Bk Channel Gating by Ca2+ and Mg2+ through a Nonselective, Low Affinity Divalent Cation Site.

X. Zhang, C.R. Solaro, and C.J. Lingle (2001)
J. Gen. Physiol. 118, 607-636
 |  Abstract »  |  Full Text »  |  PDF »

Kinetic Gating Mechanisms for Bk Channels: When Complexity Leads to Simplicity.

K. L. Magleby (2001)
J. Gen. Physiol. 118, 583-588
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Contribution of potential EF hand motifs to the calcium-dependent gating of a mouse brain large conductance, calcium-sensitive K+ channel.

A. P Braun and L. Sy (2001)
J. Physiol. 533, 681-695
 |  Abstract »  |  Full Text »  |  PDF »

Gating Properties Conferred on Bk Channels by the {beta}3b Auxiliary Subunit in the Absence of Its Nh2- and Cooh Termini.

X.-H. Zeng, J.-P. Ding, X.-M. Xia, and C. J. Lingle (2001)
J. Gen. Physiol. 117, 607-628
 |  Abstract »  |  Full Text »  |  PDF »

Maxi-K Potassium Channels: Form, Function, and Modulation of a Class of Endogenous Regulators of Intracellular Calcium.

V. K. Gribkoff, J. E. Starrett Jr., and S. I. Dworetzky (2001)
Neuroscientist 7, 166-177
 |  Abstract »  |  PDF »

Potent inhibition of the aortic smooth muscle maxi-K channel by clinical doses of ethanol.

F. S. Walters, M. Covarrubias, and J. S. Ellingson (2000)
Am J Physiol Cell Physiol 279, C1107-C1115
 |  Abstract »  |  Full Text »  |  PDF »

17-beta -Estradiol Modulation of Area Postrema Potassium Currents.

Z. Li and M. Hay (2000)
J Neurophysiol 84, 1385-1391
 |  Abstract »  |  Full Text »  |  PDF »

Role of the {beta}1 Subunit in Large-Conductance Ca2+-Activated K+ Channel Gating Energetics: Mechanisms of Enhanced Ca2+ Sensitivity.

D.H. Cox and R.W. Aldrich (2000)
J. Gen. Physiol. 116, 411-432
 |  Abstract »  |  Full Text »  |  PDF »

Voltage and Ca2+ Activation of Single Large-Conductance Ca2+-Activated K+ Channels Described by a Two-Tiered Allosteric Gating Mechanism.

B. S. Rothberg and K. L. Magleby (2000)
J. Gen. Physiol. 116, 75-100
 |  Abstract »  |  Full Text »  |  PDF »

Rectification and Rapid Activation at Low Ca2+ of Ca2+-Activated, Voltage-Dependent BK Currents: Consequences of Rapid Inactivation by a Novel beta Subunit.

X.-M. Xia, J.-P. Ding, X.-H. Zeng, K.-L. Duan, and C. J. Lingle (2000)
J. Neurosci. 20, 4890-4903
 |  Abstract »  |  Full Text »  |  PDF »

Functional Coupling of the {beta}1 Subunit to the Large Conductance Ca2+-Activated K+ Channel in the Absence of Ca2+: Increased Ca2+ Sensitivity from a Ca2+-Independent Mechanism.

C. M. Nimigean and K. L. Magleby (2000)
J. Gen. Physiol. 115, 719-736
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Nervous System beta Subunit that Downregulates Human Large Conductance Calcium-Dependent Potassium Channels.

T. M. Weiger, M. H. Holmqvist, I. B. Levitan, F. T. Clark, S. Sprague, W.-J. Huang, P. Ge, C. Wang, D. Lawson, M. E. Jurman, et al. (2000)
J. Neurosci. 20, 3563-3570
 |  Abstract »  |  Full Text »  |  PDF »

Endothelial K+ channel lacks the Ca2+ sensitivity-regulating {beta} subunit.

J. PAPASSOTIRIOU, R. KÖHLER, J. PRENEN, H. KRAUSE, M. AKBAR, J. EGGERMONT, M. PAUL, A. DISTLER, B. NILIUS, and J. HOYER (2000)
FASEB J 14, 885-894
 |  Abstract »  |  Full Text »

beta Subunits Modulate Alternatively Spliced, Large Conductance, Calcium-Activated Potassium Channels of Avian Hair Cells.

K. Ramanathan, T. H. Michael, and P. A. Fuchs (2000)
J. Neurosci. 20, 1675-1684
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Cloning and Characterization of the Intermediate-Conductance Ca2+-Activated K+ Channel in Vascular Smooth Muscle : Relationship Between KCa Channel Diversity and Smooth Muscle Cell Function.

C. B. Neylon, R. J. Lang, Y. Fu, A. Bobik, and P. H. Reinhart (1999)
Circ. Res. 85 , e33-e43
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Components of Large Conductance Calcium-Activated Potassium (BK) Channels in Mouse Pituitary Corticotropes.

M. J. Shipston, R. R. Duncan, A. G. Clark, F. A. Antoni, and L. Tian (1999)
Mol. Endocrinol. 13, 1728-1737
 |  Abstract »  |  Full Text »

Acute Activation of Maxi-K Channels (hSlo) by Estradiol Binding to the  Subunit.

M. A. Valverde, P. Rojas, J. Amigo, D. Cosmelli, P. Orio, M. I. Bahamonde, G. E. Mann, C. Vergara, and R. Latorre (1999)
Science 285, 1929-1931
 |  Abstract »  |  Full Text »

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