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Science 25 June 1993:
Vol. 260. no. 5116, pp. 1955 - 1958
DOI: 10.1126/science.8316836

Articles

Science, Vol 260, Issue 5116, 1955-1958
Copyright © 1993 by American Association for the Advancement of Science


articles

Dissociation of object and spatial processing domains in primate prefrontal cortex

FA Wilson, SP Scalaidhe, and PS Goldman-Rakic

Section of Neurobiology, Yale University School of Medicine, New Haven, CT 06511.

Areas and pathways subserving object and spatial vision are segregated in the visual system. Experiments show that the primate prefrontal cortex is similarly segregated into object and spatial domains. Neurons that code information related to stimulus identity are dissociable, both by function and region, from those that code information related to stimulus location. These findings indicate that the prefrontal cortex contains separate processing mechanisms for remembering "what" and "where" an object is.


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