Science 23 April 1993: Vol. 260. no. 5107, pp. 547 - 549 DOI: 10.1126/science.8097338

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Articles

Encephalitogenicity of Complete Freund's Adjuvant Relative to CpG Is Linked to Induction of Th17 Cells.

J. T. Tigno-Aranjuez, R. Jaini, V. K. Tuohy, P. V. Lehmann, and M. Tary-Lehmann (2009)
J. Immunol. 183, 5654-5661
 |  Abstract »  |  Full Text »  |  PDF »

How Diverse--CD4 Effector T Cells and their Functions.

Y. Y. Wan and R. A. Flavell (2009)
J Mol Cell Biol 1, 20-36
 |  Abstract »  |  Full Text »  |  PDF »

Protumor vs Antitumor Functions of IL-17.

G. Murugaiyan and B. Saha (2009)
J. Immunol. 183, 4169-4175
 |  Abstract »  |  Full Text »  |  PDF »

An Accessory Role for B Cells in the IL-12-Induced Activation of Resting Mouse NK Cells.

E. A. Haddad, L. K. Senger, and F. Takei (2009)
J. Immunol. 183, 3608-3615
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of Effector T Cells in Dry Eye Disease.

J. El Annan, S. K. Chauhan, T. Ecoiffier, Q. Zhang, D. R. Saban, and R. Dana (2009)
Invest. Ophthalmol. Vis. Sci. 50, 3802-3807
 |  Abstract »  |  Full Text »  |  PDF »

Bacillus subtilis-specific poly-{gamma}-glutamic acid regulates development pathways of naive CD4+ T cells through antigen-presenting cell-dependent and -independent mechanisms.

S. Kim, J. Y. Yang, K. Lee, K. H. Oh, M. Gi, J. M. Kim, D. J. Paik, S. Hong, and J. Youn (2009)
Int. Immunol. 21, 977-990
 |  Abstract »  |  Full Text »  |  PDF »

Suppression of Regulatory T Cells by IL-12p40 Homodimer via Nitric Oxide.

S. Brahmachari and K. Pahan (2009)
J. Immunol. 183, 2045-2058
 |  Abstract »  |  Full Text »  |  PDF »

Xenogeneic immunization with human tyrosine hydroxylase DNA vaccines suppresses growth of established neuroblastoma.

N. Huebener, S. Fest, K. Hilt, A. Schramm, A. Eggert, T. Durmus, A. Woehler, A. Stermann, M. Bleeke, B. Baykan, et al. (2009)
Mol. Cancer Ther. 8, 2392-2401
 |  Abstract »  |  Full Text »  |  PDF »

Critical Roles of NK and CD8+ T Cells in Central Nervous System Listeriosis.

T. Hayashi, S. Nagai, H. Fujii, Y. Baba, E. Ikeda, T. Kawase, and S. Koyasu (2009)
J. Immunol. 182, 6360-6368
 |  Abstract »  |  Full Text »  |  PDF »

Functional Blocking Monoclonal Antibodies against IL-12p40 Homodimer Inhibit Adoptive Transfer of Experimental Allergic Encephalomyelitis.

S. Mondal, A. Roy, and K. Pahan (2009)
J. Immunol. 182, 5013-5023
 |  Abstract »  |  Full Text »  |  PDF »

Influenza Virus and Poly(I:C) Inhibit MHC Class I-Restricted Presentation of Cell-Associated Antigens Derived from Infected Dead Cells Captured by Human Dendritic Cells.

D. Frleta, C. I. Yu, E. Klechevsky, A.-L. Flamar, G. Zurawski, J. Banchereau, and A. K. Palucka (2009)
J. Immunol. 182, 2766-2776
 |  Abstract »  |  Full Text »  |  PDF »

A Pivotal Role for CD40-Mediated IL-6 Production by Dendritic Cells during IL-17 Induction In Vivo.

G. Perona-Wright, S. J. Jenkins, R. A. O'Connor, D. Zienkiewicz, H. J. McSorley, R. M. Maizels, S. M. Anderton, and A. S. MacDonald (2009)
J. Immunol. 182, 2808-2815
 |  Abstract »  |  Full Text »  |  PDF »

Alternatively Activated Macrophages Elicited by Helminth Infection Can Be Reprogrammed to Enable Microbial Killing.

K. J. Mylonas, M. G. Nair, L. Prieto-Lafuente, D. Paape, and J. E. Allen (2009)
J. Immunol. 182, 3084-3094
 |  Abstract »  |  Full Text »  |  PDF »

Down-regulation of Gfi-1 expression by TGF-{beta} is important for differentiation of Th17 and CD103+ inducible regulatory T cells.

J. Zhu, T. S. Davidson, G. Wei, D. Jankovic, K. Cui, D. E. Schones, L. Guo, K. Zhao, E. M. Shevach, and W. E. Paul (2009)
J. Exp. Med. 206, 329-341
 |  Abstract »  |  Full Text »  |  PDF »

Colony-Stimulating Factor-1-Dependent Macrophage Functions Regulate the Maternal Decidua Immune Responses against Listeria monocytogenes Infections during Early Gestation in Mice.

X. Qiu, L. Zhu, and J. W. Pollard (2009)
Infect. Immun. 77, 85-97
 |  Abstract »  |  Full Text »  |  PDF »

Interactions of IL-12A and IL-12B Polymorphisms on the Risk of Cervical Cancer in Chinese Women.

X. Chen, S. Han, S. Wang, X. Zhou, M. Zhang, J. Dong, X. Shi, N. Qian, X. Wang, Q. Wei, et al. (2009)
Clin. Cancer Res. 15, 400-405
 |  Abstract »  |  Full Text »  |  PDF »

Selective Regulation of TCR Signaling Pathways by the CD45 Protein Tyrosine Phosphatase during Thymocyte Development.

R. Falahati and D. Leitenberg (2008)
J. Immunol. 181, 6082-6091
 |  Abstract »  |  Full Text »  |  PDF »

A Nasal Interleukin-12 DNA Vaccine Coexpressing Yersinia pestis F1-V Fusion Protein Confers Protection against Pneumonic Plague.

H. Yamanaka, T. Hoyt, X. Yang, S. Golden, C. M. Bosio, K. Crist, T. Becker, M. Maddaloni, and D. W. Pascual (2008)
Infect. Immun. 76, 4564-4573
 |  Abstract »  |  Full Text »  |  PDF »

Th1 Fate Determination in CD4+ T Cells: Notice Is Served of the Importance of IL-12!.

W. E. Paul (2008)
J. Immunol. 181, 4435-4436
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Promoter Analysis Reveals Critical Roles for SMAD-3 and ATF-2 in Expression of IL-23 p19 in Macrophages.

F. Al-Salleeh and T. M. Petro (2008)
J. Immunol. 181, 4523-4533
 |  Abstract »  |  Full Text »  |  PDF »

Disruption of the Transcription Factor Nrf2 Promotes Pro-Oxidative Dendritic Cells That Stimulate Th2-Like Immunoresponsiveness upon Activation by Ambient Particulate Matter.

M. A. Williams, T. Rangasamy, S. M. Bauer, S. Killedar, M. Karp, T. W. Kensler, M. Yamamoto, P. Breysse, S. Biswal, and S. N. Georas (2008)
J. Immunol. 181, 4545-4559
 |  Abstract »  |  Full Text »  |  PDF »

Phenotypic classification of human CD4+ T cell subsets and their differentiation.

R. Okada, T. Kondo, F. Matsuki, H. Takata, and M. Takiguchi (2008)
Int. Immunol. 20, 1189-1199
 |  Abstract »  |  Full Text »  |  PDF »

CD4 T cells: fates, functions, and faults.

J. Zhu and W. E. Paul (2008)
Blood 112, 1557-1569
 |  Abstract »  |  Full Text »  |  PDF »

Galectin-3 Is a Negative Regulator of Lipopolysaccharide-Mediated Inflammation.

Y. Li, M. Komai-Koma, D. S. Gilchrist, D. K. Hsu, F.-T. Liu, T. Springall, and D. Xu (2008)
J. Immunol. 181, 2781-2789
 |  Abstract »  |  Full Text »  |  PDF »

CpG Methylation of the IFNG Gene as a Mechanism to Induce Immunosupression in Tumor-Infiltrating Lymphocytes.

P. C. J. Janson, P. Marits, M. Thorn, R. Ohlsson, and O. Winqvist (2008)
J. Immunol. 181, 2878-2886
 |  Abstract »  |  Full Text »  |  PDF »

Macrophages Pulsed with Streptococcus pneumoniae Elicit a T Cell-Dependent Antibody Response upon Transfer into Naive Mice.

S. Vasilevsky, J. Colino, R. Puliaev, D. H. Canaday, and C. M. Snapper (2008)
J. Immunol. 181, 1787-1797
 |  Abstract »  |  Full Text »  |  PDF »

Therapeutic Administration of KM+ Lectin Protects Mice Against Paracoccidioides brasiliensis Infection via Interleukin-12 Production in a Toll-Like Receptor 2-Dependent Mechanism.

K. C. Coltri, L. L. Oliveira, C. F. Pinzan, P. E. Vendruscolo, R. Martinez, M. H. Goldman, A. Panunto-Castelo, and M.-C. Roque-Barreira (2008)
Am. J. Pathol. 173, 423-432
 |  Abstract »  |  Full Text »  |  PDF »

Inactivation of the Type IV Secretion System Reduces the Th1 Polarization of the Immune Response to Brucella abortus Infection.

H. G. Rolan and R. M. Tsolis (2008)
Infect. Immun. 76, 3207-3213
 |  Abstract »  |  Full Text »  |  PDF »

Therapeutic Vaccination with Simian Immunodeficiency Virus (SIV)-DNA+IL-12 or IL-15 Induces Distinct CD8 Memory Subsets in SIV-Infected Macaques.

R. Halwani, J. D. Boyer, B. Yassine-Diab, E. K. Haddad, T. M. Robinson, S. Kumar, R. Parkinson, L. Wu, M. K. Sidhu, R. Phillipson-Weiner, et al. (2008)
J. Immunol. 180, 7969-7979
 |  Abstract »  |  Full Text »  |  PDF »

Osteoimmunology: Interactions of the Bone and Immune System.

J. Lorenzo, M. Horowitz, and Y. Choi (2008)
Endocr. Rev. 29, 403-440
 |  Abstract »  |  Full Text »  |  PDF »

Paired Toll-like Receptor Agonists Enhance Vaccine Therapy through Induction of Interleukin-12.

R. Zheng, P. A. Cohen, C. A. Paustian, T. D. Johnson, W. T. Lee, S. Shu, and G. K. Koski (2008)
Cancer Res. 68, 4045-4049
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-12 and Host Defense against Murine Pneumocystis Pneumonia.

S. Ruan, L. McKinley, M. Zheng, X. Rudner, A. D'Souza, J. K. Kolls, and J. E. Shellito (2008)
Infect. Immun. 76, 2130-2137
 |  Abstract »  |  Full Text »  |  PDF »

Dendritic cells at the interface of innate and acquired immunity: the role for epigenetic changes.

H. Wen, M. A. Schaller, Y. Dou, C. M. Hogaboam, and S. L. Kunkel (2008)
J. Leukoc. Biol. 83, 439-446
 |  Abstract »  |  Full Text »  |  PDF »

Proliferative Expansion and Acquisition of Effector Activity by Memory CD4+ T Cells in the Lungs following Pulmonary Virus Infection.

E. L. Wissinger, W. W. Stevens, S. M. Varga, and T. J. Braciale (2008)
J. Immunol. 180, 2957-2966
 |  Abstract »  |  Full Text »  |  PDF »

Epigenetic regulation of dendritic cell-derived interleukin-12 facilitates immunosuppression after a severe innate immune response.

H. Wen, Y. Dou, C. M. Hogaboam, and S. L. Kunkel (2008)
Blood 111, 1797-1804
 |  Abstract »  |  Full Text »  |  PDF »

Th17 Cells Exhibit a Distinct Calcium Profile from Th1 and Th2 Cells and Have Th1-Like Motility and NF-AT Nuclear Localization.

K. S. Weber, M. J. Miller, and P. M. Allen (2008)
J. Immunol. 180, 1442-1450
 |  Abstract »  |  Full Text »  |  PDF »

Macrophages Are Important Determinants of Acute Ocular HSV-1 Infection in Immunized Mice.

K. Mott, D. J. Brick, N. van Rooijen, and H. Ghiasi (2007)
Invest. Ophthalmol. Vis. Sci. 48, 5605-5615
 |  Abstract »  |  Full Text »  |  PDF »

Gamma Interferon-Independent Effects of Interleukin-12 on Immunity to Salmonella enterica Serovar Typhimurium.

J. D. Price, K. R. Simpfendorfer, R. R. Mantena, J. Holden, W. R. Heath, N. van Rooijen, R. A. Strugnell, and O. L. C. Wijburg (2007)
Infect. Immun. 75, 5753-5762
 |  Abstract »  |  Full Text »  |  PDF »

LIGHT Is Critical for IL-12 Production by Dendritic Cells, Optimal CD4+ Th1 Cell Response, and Resistance to Leishmania major.

G. Xu, D. Liu, I. Okwor, Y. Wang, H. Korner, S. K. P. Kung, Y.-X. Fu, and J. E. Uzonna (2007)
J. Immunol. 179, 6901-6909
 |  Abstract »  |  Full Text »  |  PDF »

The Aryl Hydrocarbon Receptor Is Required for Optimal Resistance to Listeria monocytogenes Infection in Mice.

L. Z. Shi, N. G. Faith, Y. Nakayama, M. Suresh, H. Steinberg, and C. J. Czuprynski (2007)
J. Immunol. 179, 6952-6962
 |  Abstract »  |  Full Text »  |  PDF »

Syndecan-4 Mediates the Coinhibitory Function of DC-HIL on T Cell Activation.

J.-S. Chung, I. Dougherty, P. D. Cruz Jr., and K. Ariizumi (2007)
J. Immunol. 179, 5778-5784
 |  Abstract »  |  Full Text »  |  PDF »

Generation of CD8 T Cell Memory Is Regulated by IL-12.

E. L. Pearce and H. Shen (2007)
J. Immunol. 179, 2074-2081
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-12: Biological Properties and Clinical Application.

M. Del Vecchio, E. Bajetta, S. Canova, M. T. Lotze, A. Wesa, G. Parmiani, and A. Anichini (2007)
Clin. Cancer Res. 13, 4677-4685
 |  Abstract »  |  Full Text »  |  PDF »

Exogenous Farnesol Interferes with the Normal Progression of Cytokine Expression during Candidiasis in a Mouse Model.

D. H. M. L. P. Navarathna, K. W. Nickerson, G. E. Duhamel, T. R. Jerrels, and T. M. Petro (2007)
Infect. Immun. 75, 4006-4011
 |  Abstract »  |  Full Text »  |  PDF »

IL-6-dependent and -independent pathways in the development of interleukin 17-producing T helper cells.

A. Kimura, T. Naka, and T. Kishimoto (2007)
PNAS 104, 12099-12104
 |  Abstract »  |  Full Text »  |  PDF »

Immunomodulatory Effects of Viral TLR Ligands on Experimental Asthma Depend on the Additive Effects of IL-12 and IL-10.

S. Sel, M. Wegmann, S. Sel, S. Bauer, H. Garn, G. Alber, and H. Renz (2007)
J. Immunol. 178, 7805-7813
 |  Abstract »  |  Full Text »  |  PDF »

IL-6-gp130-STAT3 in T cells directs the development of IL-17+ Th with a minimum effect on that of Treg in the steady state.

M. Nishihara, H. Ogura, N. Ueda, M. Tsuruoka, C. Kitabayashi, F. Tsuji, H. Aono, K. Ishihara, E. Huseby, U. A. K. Betz, et al. (2007)
Int. Immunol. 19, 695-702
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of mast cells in IL-12/23 p40 production is essential for survival from polymicrobial infections.

N. Nakano, C. Nishiyama, S. Kanada, Y. Niwa, N. Shimokawa, H. Ushio, M. Nishiyama, K. Okumura, and H. Ogawa (2007)
Blood 109, 4846-4855
 |  Abstract »  |  Full Text »  |  PDF »

DC-HIL is a negative regulator of T lymphocyte activation.

J.-S. Chung, K. Sato, I. I. Dougherty, P. D. Cruz Jr, and K. Ariizumi (2007)
Blood 109, 4320-4327
 |  Abstract »  |  Full Text »  |  PDF »

New differentiation pathway for double-negative regulatory T cells that regulates the magnitude of immune responses.

D. Zhang, W. Yang, N. Degauque, Y. Tian, A. Mikita, and X. X. Zheng (2007)
Blood 109, 4071-4079
 |  Abstract »  |  Full Text »  |  PDF »

Toll-like receptor 2-mediated dendritic cell activation by a Porphyromonas gingivalis synthetic lipopeptide.

Y. Asai, Y. Makimura, and T. Ogawa (2007)
J. Med. Microbiol. 56, 459-465
 |  Abstract »  |  Full Text »  |  PDF »

Immunostimulatory RNA oligonucleotides trigger an antigen-specific cytotoxic T-cell and IgG2a response.

C. Bourquin, L. Schmidt, V. Hornung, C. Wurzenberger, D. Anz, N. Sandholzer, S. Schreiber, A. Voelkl, G. Hartmann, and S. Endres (2007)
Blood 109, 2953-2960
 |  Abstract »  |  Full Text »  |  PDF »

Dyslipidemia inhibits Toll-like receptor-induced activation of CD8{alpha}-negative dendritic cells and protective Th1 type immunity.

A. T. Shamshiev, F. Ampenberger, B. Ernst, L. Rohrer, B. J. Marsland, and M. Kopf (2007)
J. Exp. Med. 204, 441-452
 |  Abstract »  |  Full Text »  |  PDF »

Peroxisome Proliferator-Activated Receptor-{gamma} Agonists Suppress the Production of IL-12 Family Cytokines by Activated Glia.

J. Xu and P. D. Drew (2007)
J. Immunol. 178, 1904-1913
 |  Abstract »  |  Full Text »  |  PDF »

Selective abrogation of Th1 response by STA-5326, a potent IL-12/IL-23 inhibitor.

Y. Wada, R. Lu, D. Zhou, J. Chu, T. Przewloka, S. Zhang, L. Li, Y. Wu, J. Qin, V. Balasubramanyam, et al. (2007)
Blood 109, 1156-1164
 |  Abstract »  |  Full Text »  |  PDF »

Alum with Interleukin-12 Augments Immunity to a Melanoma Peptide Vaccine: Correlation with Time to Relapse in Patients with Resected High-Risk Disease.

O. Hamid, J. C. Solomon, R. Scotland, M. Garcia, S. Sian, W. Ye, S. L. Groshen, and J. S. Weber (2007)
Clin. Cancer Res. 13, 215-222
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: IL-12 Inversely Regulates T-bet and Eomesodermin Expression during Pathogen-Induced CD8+ T Cell Differentiation.

N. Takemoto, A. M. Intlekofer, J. T. Northrup, E. J. Wherry, and S. L. Reiner (2006)
J. Immunol. 177, 7515-7519
 |  Abstract »  |  Full Text »  |  PDF »

Macrophages and Myeloid Dendritic Cells, but Not Plasmacytoid Dendritic Cells, Produce IL-10 in Response to MyD88- and TRIF-Dependent TLR Signals, and TLR-Independent Signals.

A. Boonstra, R. Rajsbaum, M. Holman, R. Marques, C. Asselin-Paturel, J. P. Pereira, E. E. M. Bates, S. Akira, P. Vieira, Y.-J. Liu, et al. (2006)
J. Immunol. 177, 7551-7558
 |  Abstract »  |  Full Text »  |  PDF »

Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion.

J. Zhu, D. Jankovic, A. Grinberg, L. Guo, and W. E. Paul (2006)
PNAS 103, 18214-18219
 |  Abstract »  |  Full Text »  |  PDF »

Medium-chain Fatty Acids as Ligands for Orphan G Protein-coupled Receptor GPR84.

J. Wang, X. Wu, N. Simonavicius, H. Tian, and L. Ling (2006)
J. Biol. Chem. 281, 34457-34464
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Characteristics of Murine STAT4 Activation in Response to IL-12 and IFN-{alpha}.

L. S. Berenson, M. Gavrieli, J. D. Farrar, T. L. Murphy, and K. M. Murphy (2006)
J. Immunol. 177, 5195-5203
 |  Abstract »  |  Full Text »  |  PDF »

Establishment of Lymphotoxin beta Receptor Signaling-Dependent Cell Lines with Follicular Dendritic Cell Phenotypes from Mouse Lymph Nodes.

Y. Nishikawa, M. Hikida, M. Magari, N. Kanayama, M. Mori, H. Kitamura, T. Kurosaki, and H. Ohmori (2006)
J. Immunol. 177, 5204-5214
 |  Abstract »  |  Full Text »  |  PDF »

In the Absence of Reactive Oxygen Species, T Cells Default to a Th1 Phenotype and Mediate Protection against Pulmonary Cryptococcus neoformans Infection.

R. J. Snelgrove, L. Edwards, A. E. Williams, A. J. Rae, and T. Hussell (2006)
J. Immunol. 177, 5509-5516
 |  Abstract »  |  Full Text »  |  PDF »

Rapid Development of a Gamma Interferon-Secreting Glycolipid/CD1d-Specific V{alpha}14+ NK1.1- T-Cell Subset after Bacterial Infection..

M. Emoto, I. Yoshizawa, Y. Emoto, M. Miamoto, R. Hurwitz, and S. H. E. Kaufmann (2006)
Infect. Immun. 74, 5903-5913
 |  Abstract »  |  Full Text »  |  PDF »

An Anti-IL-12p40 Antibody Down-Regulates Type 1 Cytokines, Chemokines, and IL-12/IL-23 in Psoriasis.

E. Toichi, G. Torres, T. S. McCormick, T. Chang, M. A. Mascelli, C. L. Kauffman, N. Aria, A. B. Gottlieb, D. E. Everitt, B. Frederick, et al. (2006)
J. Immunol. 177, 4917-4926
 |  Abstract »  |  Full Text »  |  PDF »

IFN-{gamma} and T-bet Expression in Human Dendritic Cells from Normal Donors and Cancer Patients Is Controlled through Mechanisms Involving ERK-1/2-Dependent and IL-12-Independent Pathways.

H. Li, W. Wojciechowski, C. Dell'Agnola, N. E. Lopez, and I. Espinoza-Delgado (2006)
J. Immunol. 177, 3554-3563
 |  Abstract »  |  Full Text »  |  PDF »

T Cell-Dependent Activation of Dendritic Cells Requires IL-12 and IFN-{gamma} Signaling in T Cells.

F. Miro, C. Nobile, N. Blanchard, M. Lind, O. Filipe-Santos, C. Fieschi, A. Chapgier, G. Vogt, L. de Beaucoudrey, D. S. Kumararatne, et al. (2006)
J. Immunol. 177, 3625-3634
 |  Abstract »  |  Full Text »  |  PDF »

IL-10 Is Required for Optimal CD8 T Cell Memory following Listeria monocytogenes Infection.

K. E. Foulds, M. J. Rotte, and R. A. Seder (2006)
J. Immunol. 177, 2565-2574
 |  Abstract »  |  Full Text »  |  PDF »

Visualization of IL-12/23p40 In Vivo Reveals Immunostimulatory Dendritic Cell Migrants that Promote Th1 Differentiation.

R. L. Reinhardt, S. Hong, S.-J. Kang, Z.-e. Wang, and R. M. Locksley (2006)
J. Immunol. 177, 1618-1627
 |  Abstract »  |  Full Text »  |  PDF »

Silymarin inhibits UV radiation-induced immunosuppression through augmentation of interleukin-12 in mice..

S. M. Meeran, S. Katiyar, C. A. Elmets, and S. K. Katiyar (2006)
Mol. Cancer Ther. 5, 1660-1668
 |  Abstract »  |  Full Text »  |  PDF »

Strong TCR Signaling, TLR Ligands, and Cytokine Redundancies Ensure Robust Development of Type 1 Effector T Cells..

C. Nembrini, B. Abel, M. Kopf, and B. J. Marsland (2006)
J. Immunol. 176, 7180-7188
 |  Abstract »  |  Full Text »  |  PDF »

T Cell-Independent, TLR-Induced IL-12p70 Production in Primary Human Monocytes..

I. Bekeredjian-Ding, S. I. Roth, S. Gilles, T. Giese, A. Ablasser, V. Hornung, S. Endres, and G. Hartmann (2006)
J. Immunol. 176, 7438-7446
 |  Abstract »  |  Full Text »  |  PDF »

Differential expression of inducible nitric oxide synthase and IL-12 between peritoneal and splenic macrophages stimulated with LPS plus IFN-{gamma} is associated with the activation of extracellular signal-related kinase.

Y.-N. Zhu, Y.-F. Yang, S. Ono, X.-G. Zhong, Y.-H. Feng, Y.-X. Ren, J. Ni, Y.-F. Fu, W. Tang, and J.-P. Zuo (2006)
Int. Immunol. 18, 981-990
 |  Abstract »  |  Full Text »  |  PDF »

Severe Sepsis Exacerbates Cell-Mediated Immunity in the Lung Due to an Altered Dendritic Cell Cytokine Profile.

H. Wen, C. M. Hogaboam, J. Gauldie, and S. L. Kunkel (2006)
Am. J. Pathol. 168, 1940-1950
 |  Abstract »  |  Full Text »  |  PDF »

SLAM/SLAM interactions inhibit CD40-induced production of inflammatory cytokines in monocyte-derived dendritic cells.

B. Rethi, P. Gogolak, I. Szatmari, A. Veres, E. Erdos, L. Nagy, E. Rajnavolgyi, C. Terhorst, and A. Lanyi (2006)
Blood 107, 2821-2829
 |  Abstract »  |  Full Text »  |  PDF »

T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription.

T. Usui, J. C. Preiss, Y. Kanno, Z. J. Yao, J. H. Bream, J. J. O'Shea, and W. Strober (2006)
J. Exp. Med. 203, 755-766
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: The Direct Action of Type I IFN on CD4 T Cells Is Critical for Sustaining Clonal Expansion in Response to a Viral but Not a Bacterial Infection.

C. Havenar-Daughton, G. A. Kolumam, and K. Murali-Krishna (2006)
J. Immunol. 176, 3315-3319
 |  Abstract »  |  Full Text »  |  PDF »

Hydrogen peroxide inhibits IL-12 p40 induction in macrophages by inhibiting c-rel translocation to the nucleus through activation of calmodulin protein.

N. Khan, S. S. Rahim, C. S. Boddupalli, S. Ghousunnissa, S. Padma, N. Pathak, D. Thiagarajan, S. E. Hasnain, and S. Mukhopadhyay (2006)
Blood 107, 1513-1520
 |  Abstract »  |  Full Text »  |  PDF »

Therapeutic Modulation of Akt Activity and Antitumor Efficacy of Interleukin-12 Against Orthotopic Murine Neuroblastoma.

T. Khan, J. A. Hixon, J. K. Stauffer, E. Lincoln, T. C. Back, J. Brenner, S. Lockett, K. Nagashima, D. Powell, and J. M. Wigginton (2006)
J Natl Cancer Inst 98, 190-202
 |  Abstract »  |  Full Text »  |  PDF »

Responsiveness of Naive CD4 T Cells to Polarizing Cytokine Determines the Ratio of Th1 and Th2 Cell Differentiation.

N. Mikhalkevich, B. Becknell, M. A. Caligiuri, M. D. Bates, R. Harvey, and W.-p. Zheng (2006)
J. Immunol. 176, 1553-1560
 |  Abstract »  |  Full Text »  |  PDF »

MAP kinase phosphatase 1 controls innate immune responses and suppresses endotoxic shock.

Q. Zhao, X. Wang, L. D. Nelin, Y. Yao, R. Matta, M. E. Manson, R. S. Baliga, X. Meng, C. V. Smith, J. A. Bauer, et al. (2006)
J. Exp. Med. 203, 131-140
 |  Abstract »  |  Full Text »  |  PDF »

Dietary grape-seed proanthocyanidin inhibition of ultraviolet B-induced immune suppression is associated with induction of IL-12.

S. D. Sharma and S. K. Katiyar (2006)
Carcinogenesis 27, 95-102
 |  Abstract »  |  Full Text »  |  PDF »

Helminth-Primed Dendritic Cells Alter the Host Response to Enteric Bacterial Infection.

C.-C. Chen, S. Louie, B. A. McCormick, W. A. Walker, and H. N. Shi (2006)
J. Immunol. 176, 472-483
 |  Abstract »  |  Full Text »  |  PDF »

Macrophages induce an allergen-specific and long-term suppression in a mouse asthma model.

J. L. M. Vissers, B. C. A. M. van Esch, G. A. Hofman, and A. J. M. van Oosterhout (2005)
Eur. Respir. J. 26, 1040-1046
 |  Abstract »  |  Full Text »  |  PDF »

Urocortin 2 Suppresses Host Resistance to Listeria monocytogenes Infection via Up-Regulation of Interleukin-10.

H. Sashinami, K. Kageyama, T. Suda, and A. Nakane (2005)
Endocrinology 146, 5003-5011
 |  Abstract »  |  Full Text »  |  PDF »

IL-12 Is Required for Induction but Not Maintenance of Protective, Memory Responses to Blastomyces dermatitidis: Implications for Vaccine Development in Immune-Deficient Hosts.

M. Wuthrich, T. Warner, and B. S. Klein (2005)
J. Immunol. 175, 5288-5297
 |  Abstract »  |  Full Text »  |  PDF »

Th1 Cytokines Are Essential for Placental Immunity to Listeria monocytogenes.

E. M. Barber, M. Fazzari, and J. W. Pollard (2005)
Infect. Immun. 73, 6322-6331
 |  Abstract »  |  Full Text »  |  PDF »

Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment.

H. Yamane, J. Zhu, and W. E. Paul (2005)
J. Exp. Med. 202, 793-804
 |  Abstract »  |  Full Text »  |  PDF »

Fusion to Listeriolysin O and Delivery by Listeria monocytogenes Enhances the Immunogenicity of HER-2/neu and Reveals Subdominant Epitopes in the FVB/N Mouse.

R. Singh, M. E. Dominiecki, E. M. Jaffee, and Y. Paterson (2005)
J. Immunol. 175, 3663-3673
 |  Abstract »  |  Full Text »  |  PDF »

Negative control of basophil expansion by IRF-2 critical for the regulation of Th1/Th2 balance.

S. Hida, M. Tadachi, T. Saito, and S. Taki (2005)
Blood 106, 2011-2017
 |  Abstract »  |  Full Text »  |  PDF »

Blockade of Interleukin-12 Function by Protein Vaccination Attenuates Atherosclerosis.

A.D. Hauer, C. Uyttenhove, P. de Vos, V. Stroobant, J.C. Renauld, T.J.C. van Berkel, J. van Snick, and J. Kuiper (2005)
Circulation 112, 1054-1062
 |  Abstract »  |  Full Text »  |  PDF »

Both Dendritic Cells and Macrophages Can Stimulate Naive CD8 T Cells In Vivo to Proliferate, Develop Effector Function, and Differentiate into Memory Cells.

L.-A. M. Pozzi, J. W. Maciaszek, and K. L. Rock (2005)
J. Immunol. 175, 2071-2081
 |  Abstract »  |  Full Text »  |  PDF »

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