Science 26 March 1993: Vol. 259. no. 5103, pp. 1912 - 1915 DOI: 10.1126/science.8096091

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Articles

TLR3-mediated NF-{kappa}B signaling in human esophageal epithelial cells.

D. M. Lim, S. Narasimhan, C. Z. Michaylira, and M.-L. Wang (2009)
Am J Physiol Gastrointest Liver Physiol 297, G1172-G1180
 |  Abstract »  |  Full Text »  |  PDF »

Kinetic enhancement of NF-{kappa}B{middle dot}DNA dissociation by I{kappa}B{alpha}.

S. Bergqvist, V. Alverdi, B. Mengel, A. Hoffmann, G. Ghosh, and E. A. Komives (2009)
PNAS 106, 19328-19333
 |  Abstract »  |  Full Text »  |  PDF »

A Noisy Paracrine Signal Determines the Cellular NF-{kappa}B Response to Lipopolysaccharide.

T. K. Lee, E. M. Denny, J. C. Sanghvi, J. E. Gaston, N. D. Maynard, J. J. Hughey, and M. W. Covert (2009)
Science Signaling 2, ra65
 |  Abstract »  |  Full Text »  |  PDF »

Cellular Stress Response Pathway System as a Sentinel Ensemble in Toxicological Screening.

S. O. Simmons, C.-Y. Fan, and R. Ramabhadran (2009)
Toxicol. Sci. 111, 202-225
 |  Abstract »  |  Full Text »  |  PDF »

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses.

T. H. Mogensen (2009)
Clin. Microbiol. Rev. 22, 240-273
 |  Abstract »  |  Full Text »  |  PDF »

CXCL8/IL8 Stimulates Vascular Endothelial Growth Factor (VEGF) Expression and the Autocrine Activation of VEGFR2 in Endothelial Cells by Activating NF{kappa}B through the CBM (Carma3/Bcl10/Malt1) Complex.

D. Martin, R. Galisteo, and J. S. Gutkind (2009)
J. Biol. Chem. 284, 6038-6042
 |  Abstract »  |  Full Text »  |  PDF »

NF-{kappa}B1 p105 Regulates T Cell Homeostasis and Prevents Chronic Inflammation.

M. Chang, A. J. Lee, L. Fitzpatrick, M. Zhang, and S.-C. Sun (2009)
J. Immunol. 182, 3131-3138
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Liver X Receptors Promotes Neuroprotection and Reduces Brain Inflammation in Experimental Stroke.

J. R. Morales, I. Ballesteros, J. M. Deniz, O. Hurtado, J. Vivancos, F. Nombela, I. Lizasoain, A. Castrillo, and M. A. Moro (2008)
Circulation 118, 1450-1459
 |  Abstract »  |  Full Text »  |  PDF »

Autoregulation of Th1-mediated inflammation by twist1.

U. Niesner, I. Albrecht, M. Janke, C. Doebis, C. Loddenkemper, M. H. Lexberg, K. Eulenburg, S. Kreher, J. Koeck, R. Baumgrass, et al. (2008)
J. Exp. Med. 205, 1889-1901
 |  Abstract »  |  Full Text »  |  PDF »

Increased Rac1b Expression Sustains Colorectal Tumor Cell Survival.

P. Matos and P. Jordan (2008)
Mol. Cancer Res. 6, 1178-1184
 |  Abstract »  |  Full Text »  |  PDF »

Roles of Cytosolic Phospholipase A2 and Src Kinase in the Early Action of 2,3,7,8-Tetrachlorodibenzo-p-dioxin through a Nongenomic Pathway in MCF10A Cells.

B. Dong and F. Matsumura (2008)
Mol. Pharmacol. 74, 255-263
 |  Abstract »  |  Full Text »  |  PDF »

RelA Ser276 Phosphorylation Is Required for Activation of a Subset of NF-{kappa}B-Dependent Genes by Recruiting Cyclin-Dependent Kinase 9/Cyclin T1 Complexes.

D. E. Nowak, B. Tian, M. Jamaluddin, I. Boldogh, L. A. Vergara, S. Choudhary, and A. R. Brasier (2008)
Mol. Cell. Biol. 28, 3623-3638
 |  Abstract »  |  Full Text »  |  PDF »

Tumor Necrosis Factor (TNF)-{alpha} Persistently Activates Nuclear Factor-{kappa}B Signaling through the Type 2 TNF Receptor in Chromaffin Cells: Implications for Long-Term Regulation of Neuropeptide Gene Expression in Inflammation.

D. Ait-Ali, V. Turquier, Y. Tanguy, E. Thouennon, H. Ghzili, L. Mounien, C. Derambure, S. Jegou, J.-P. Salier, H. Vaudry, et al. (2008)
Endocrinology 149, 2840-2852
 |  Abstract »  |  Full Text »  |  PDF »

PRDM1 is involved in chemoresistance of T-cell lymphoma and down-regulated by the proteasome inhibitor.

W.-L. Zhao, Y.-Y. Liu, Q.-L. Zhang, L. Wang, C. Leboeuf, Y.-W. Zhang, J. Ma, J.-F. Garcia, Y.-P. Song, J.-M. Li, et al. (2008)
Blood 111, 3867-3871
 |  Abstract »  |  Full Text »  |  PDF »

Dicoumarol down-regulates human PTTG1/Securin mRNA expression through inhibition of Hsp90.

A. Hernandez, G. Lopez-Lluch, J. A. Bernal, P. Navas, and J. A. Pintor-Toro (2008)
Mol. Cancer Ther. 7, 474-482
 |  Abstract »  |  Full Text »  |  PDF »

Targeted inactivation of the COP9 signalosome impairs multiple stagesof T cell development.

M. Panattoni, F. Sanvito, V. Basso, C. Doglioni, G. Casorati, E. Montini, J. R. Bender, A. Mondino, and R. Pardi (2008)
J. Exp. Med. 205, 465-477
 |  Abstract »  |  Full Text »  |  PDF »

Prostaglandin H synthase-2 gene regulation in the amnion at labour: histone acetylation and nuclear factor kappa B binding to the promoter in vivo.

C.M. Mitchell, R.F. Johnson, W.B. Giles, and T. Zakar (2008)
Mol. Hum. Reprod. 14, 53-59
 |  Abstract »  |  Full Text »  |  PDF »

NLRP2, an Inhibitor of the NF-{kappa}B Pathway, Is Transcriptionally Activated by NF-{kappa}B and Exhibits a Nonfunctional Allelic Variant.

A. Fontalba, O. Gutierrez, and J. L. Fernandez-Luna (2007)
J. Immunol. 179, 8519-8524
 |  Abstract »  |  Full Text »  |  PDF »

NF-{kappa}B Signaling Regulates Functional Expression of the MHC Class I-Related Neonatal Fc Receptor for IgG via Intronic Binding Sequences.

X. Liu, L. Ye, G. J. Christianson, J.-Q. Yang, D. C. Roopenian, and X. Zhu (2007)
J. Immunol. 179, 2999-3011
 |  Abstract »  |  Full Text »  |  PDF »

RhoA regulation of NF-{kappa}B activation is mediated by COX-2-dependent feedback inhibition of IKK in kidney epithelial cells.

W. W. Polk, M. E. Ellis, J. V. Kushleika, P. L. Simmonds, and J. S. Woods (2007)
Am J Physiol Cell Physiol 293, C1160-C1170
 |  Abstract »  |  Full Text »  |  PDF »

Human chorionic gonadotrophin attenuates NF-{kappa}B activation and cytokine expression of endometriotic stromal cells.

A.V. Huber, L. Saleh, J. Prast, P. Haslinger, and M. Knofler (2007)
Mol. Hum. Reprod. 13, 595-604
 |  Abstract »  |  Full Text »  |  PDF »

Sustained Induction of NF-{kappa}B Is Required for Efficient Expression of Latent Human Immunodeficiency Virus Type 1.

S. A. Williams, H. Kwon, L.-F. Chen, and W. C. Greene (2007)
J. Virol. 81, 6043-6056
 |  Abstract »  |  Full Text »  |  PDF »

Deubiquitinating Enzyme CYLD Regulates the Peripheral Development and Naive Phenotype Maintenance of B Cells.

W. Jin, W. R. Reiley, A. J. Lee, A. Wright, X. Wu, M. Zhang, and S.-C. Sun (2007)
J. Biol. Chem. 282, 15884-15893
 |  Abstract »  |  Full Text »  |  PDF »

Developmentally regulated tumor necrosis factor-{alpha} induced nuclear factor-{kappa}B activation in intestinal epithelium.

E. C. Claud, X. Zhang, E. O. Petrof, and J. Sun (2007)
Am J Physiol Gastrointest Liver Physiol 292, G1411-G1419
 |  Abstract »  |  Full Text »  |  PDF »

Adipocyte Enhancer-binding Protein-1 Promotes Macrophage Inflammatory Responsiveness by Up-Regulating NF-{kappa}B via I{kappa}B{alpha} Negative Regulation.

A. Majdalawieh, L. Zhang, and H.-S. Ro (2007)
Mol. Biol. Cell 18, 930-942
 |  Abstract »  |  Full Text »  |  PDF »

Extensive Immunoglobulin Production Sensitizes Myeloma Cells for Proteasome Inhibition.

S. Meister, U. Schubert, K. Neubert, K. Herrmann, R. Burger, M. Gramatzki, S. Hahn, S. Schreiber, S. Wilhelm, M. Herrmann, et al. (2007)
Cancer Res. 67, 1783-1792
 |  Abstract »  |  Full Text »  |  PDF »

Regions of I{kappa}B{alpha} that are critical for its inhibition of NF-{kappa}B{middle dot}DNA interaction fold upon binding to NF-{kappa}B.

S. M. E. Truhlar, J. W. Torpey, and E. A. Komives (2006)
PNAS 103, 18951-18956
 |  Abstract »  |  Full Text »  |  PDF »

Regulation and Function of IKK and IKK-Related Kinases.

H. Hacker and M. Karin (2006)
Sci. STKE 2006, re13
 |  Abstract »  |  Full Text »  |  PDF »

NF-{kappa}B/Rel Regulates Inhibitory and Excitatory Neuronal Function and Synaptic Plasticity..

A. O'Mahony, J. Raber, M. Montano, E. Foehr, V. Han, S.-m. Lu, H. Kwon, A. LeFevour, S. Chakraborty-Sett, and W. C. Greene (2006)
Mol. Cell. Biol. 26, 7283-7298
 |  Abstract »  |  Full Text »  |  PDF »

Activation of NF-{kappa}B by the intracellular expression of NF-{kappa}B-inducing kinase acts as a powerful vaccine adjuvant.

E. Andreakos, R. O. Williams, J. Wales, B. M. Foxwell, and M. Feldmann (2006)
PNAS 103, 14459-14464
 |  Abstract »  |  Full Text »  |  PDF »

Cytokine-Induced Proapoptotic Gene Expression in Insulin-Producing Cells Is Related to Rapid, Sustained, and Nonoscillatory Nuclear Factor-{kappa}B Activation.

F. Ortis, A. K. Cardozo, D. Crispim, J. Storling, T. Mandrup-Poulsen, and D. L. Eizirik (2006)
Mol. Endocrinol. 20, 1867-1879
 |  Abstract »  |  Full Text »  |  PDF »

Minimal model of spiky oscillations in NF-{kappa}B signaling.

S. Krishna, M. H. Jensen, and K. Sneppen (2006)
PNAS 103, 10840-10845
 |  Abstract »  |  Full Text »  |  PDF »

Deregulated Activation of Oncoprotein Kinase Tpl2/Cot in HTLV-I-transformed T Cells.

G. Babu, M. Waterfield, M. Chang, X. Wu, and S.-C. Sun (2006)
J. Biol. Chem. 281, 14041-14047
 |  Abstract »  |  Full Text »  |  PDF »

Protein Methyltransferase 2 Inhibits NF-{kappa}B Function and Promotes Apoptosis.

L. Ganesh, T. Yoshimoto, N. C. Moorthy, W. Akahata, M. Boehm, E. G. Nabel, and G. J. Nabel (2006)
Mol. Cell. Biol. 26, 3864-3874
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Member of the I{kappa}B Family, Human I{kappa}B-{zeta}, Inhibits Transactivation of p65 and Its DNA Binding.

G. Totzke, F. Essmann, S. Pohlmann, C. Lindenblatt, R. U. Janicke, and K. Schulze-Osthoff (2006)
J. Biol. Chem. 281, 12645-12654
 |  Abstract »  |  Full Text »  |  PDF »

NF-{kappa}B is essential for the progression of KSHV- and EBV-infected lymphomas in vivo.

S. A. Keller, D. Hernandez-Hopkins, J. Vider, V. Ponomarev, E. Hyjek, E. J. Schattner, and E. Cesarman (2006)
Blood 107, 3295-3302
 |  Abstract »  |  Full Text »  |  PDF »

Persistent Interleukin-1beta Signaling Causes Long Term Activation of NF{kappa}B in a Promoter-specific Manner in Human Glial Cells.

B. D. Griffin and P. N. Moynagh (2006)
J. Biol. Chem. 281, 10316-10326
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Adenosine A1 Receptor Expression by Pertussis Toxin via an Adenosine 5'-Diphosphate Ribosylation-Independent Pathway.

S. Jajoo, D. Mukherjea, S. Pingle, Y. Sekino, and V. Ramkumar (2006)
J. Pharmacol. Exp. Ther. 317, 1-10
 |  Abstract »  |  Full Text »  |  PDF »

Functional inactivation of p53 by human T-cell leukemia virus type 1 Tax protein: mechanisms and clinical implications.

Y. Tabakin-Fix, I. Azran, Y. Schavinky-Khrapunsky, O. Levy, and M. Aboud (2006)
Carcinogenesis 27, 673-681
 |  Abstract »  |  Full Text »  |  PDF »

Antianoikis Effect of Nuclear Factor-{kappa}B through Up-regulated Expression of Osteoprotegerin, BCL-2, and IAP-1.

M. Toruner, M. Fernandez-Zapico, J. J. Sha, L. Pham, R. Urrutia, and L. J. Egan (2006)
J. Biol. Chem. 281, 8686-8696
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Human Immunodeficiency Virus Type 1 Replication in Latently Infected Cells by a Novel I{kappa}B Kinase Inhibitor.

A. F. B. Victoriano, K. Asamitsu, Y. Hibi, K. Imai, N. G. Barzaga, and T. Okamoto (2006)
Antimicrob. Agents Chemother. 50, 547-555
 |  Abstract »  |  Full Text »  |  PDF »

Low K+ Promotes NF-{kappa}B/DNA Binding in Neuronal Apoptosis Induced by K+ Loss.

Y. Tao, D. Yan, Q. Yang, R. Zeng, and Y. Wang (2006)
Mol. Cell. Biol. 26, 1038-1050
 |  Abstract »  |  Full Text »  |  PDF »

Respiratory Syncytial Virus-Inducible BCL-3 Expression Antagonizes the STAT/IRF and NF-{kappa}B Signaling Pathways by Inducing Histone Deacetylase 1 Recruitment to the Interleukin-8 Promoter.

M. Jamaluddin, S. Choudhary, S. Wang, A. Casola, R. Huda, R. P. Garofalo, S. Ray, and A. R. Brasier (2005)
J. Virol. 79, 15302-15313
 |  Abstract »  |  Full Text »  |  PDF »

3-Phosphoinositide-dependent Protein Kinase-1-mediated I{kappa}B Kinase {beta} (IKKB) Phosphorylation Activates NF-{kappa}B Signaling.

H. Tanaka, N. Fujita, and T. Tsuruo (2005)
J. Biol. Chem. 280, 40965-40973
 |  Abstract »  |  Full Text »  |  PDF »

SIRT1 Protects against Microglia-dependent Amyloid-{beta} Toxicity through Inhibiting NF-{kappa}B Signaling.

J. Chen, Y. Zhou, S. Mueller-Steiner, L.-F. Chen, H. Kwon, S. Yi, L. Mucke, and L. Gan (2005)
J. Biol. Chem. 280, 40364-40374
 |  Abstract »  |  Full Text »  |  PDF »

Up-regulation of CXCR4 Expression in PC-3 Cells by Stromal-Derived Factor-1{alpha} (CXCL12) Increases Endothelial Adhesion and Transendothelial Migration: Role of MEK/ERK Signaling Pathway-Dependent NF-{kappa}B Activation.

P. Kukreja, A. B. Abdel-Mageed, D. Mondal, K. Liu, and K. C. Agrawal (2005)
Cancer Res. 65, 9891-9898
 |  Abstract »  |  Full Text »  |  PDF »

TFF3 modulates NF-{kappa}B and a novel negative regulatory molecule of NF-{kappa}B in intestinal epithelial cells via a mechanism distinct from TNF-{alpha}.

Y.-Q. Zhu and X.-D. Tan (2005)
Am J Physiol Cell Physiol 289, C1085-C1093
 |  Abstract »  |  Full Text »  |  PDF »

Positive Regulation of I{kappa}B Kinase Signaling by Protein Serine/Threonine Phosphatase 2A.

A. E. Kray, R. S. Carter, K. N. Pennington, R. J. Gomez, L. E. Sanders, J. M. Llanes, W. N. Khan, D. W. Ballard, and B. E. Wadzinski (2005)
J. Biol. Chem. 280, 35974-35982
 |  Abstract »  |  Full Text »  |  PDF »

Achieving Stability of Lipopolysaccharide-Induced NF-{kappa}B Activation.

M. W. Covert, T. H. Leung, J. E. Gaston, and D. Baltimore (2005)
Science 309, 1854-1857
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Innate Immunity Conferred by B Cells Is Regulated by Caspase-8.

D. R. Beisner, I. L. Ch'en, R. V. Kolla, A. Hoffmann, and S. M. Hedrick (2005)
J. Immunol. 175, 3469-3473
 |  Abstract »  |  Full Text »  |  PDF »

Constitutive Nuclear Expression of the I{kappa}B Kinase Complex and Its Activation in Human Neutrophils.

T. Ear, A. Cloutier, and P. P. McDonald (2005)
J. Immunol. 175, 1834-1842
 |  Abstract »  |  Full Text »  |  PDF »

RelA/p65 Regulation of I{kappa}B{beta}.

E. Hertlein, J. Wang, K. J. Ladner, N. Bakkar, and D. C. Guttridge (2005)
Mol. Cell. Biol. 25, 4956-4968
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase C-dependent Regulation of NAG-1/Placental Bone Morphogenic Protein/MIC-1 Expression in LNCaP Prostate Carcinoma Cells.

M. Shim and T. E. Eling (2005)
J. Biol. Chem. 280, 18636-18642
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear Factor {kappa}B Signaling in Atherogenesis.

M. P.J. de Winther, E. Kanters, G. Kraal, and M. H. Hofker (2005)
Arterioscler Thromb Vasc Biol 25, 904-914
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Direct Genomic Targets Downstream of the Nuclear Factor-{kappa}B Transcription Factor Mediating Tumor Necrosis Factor Signaling.

B. Tian, D. E. Nowak, M. Jamaluddin, S. Wang, and A. R. Brasier (2005)
J. Biol. Chem. 280, 17435-17448
 |  Abstract »  |  Full Text »  |  PDF »

An Atypical Tumor Necrosis Factor (TNF) Receptor-associated Factor-binding Motif of B Cell-activating Factor Belonging to the TNF Family (BAFF) Receptor Mediates Induction of the Noncanonical NF-{kappa}B Signaling Pathway.

M. D. Morrison, W. Reiley, M. Zhang, and S.-C. Sun (2005)
J. Biol. Chem. 280, 10018-10024
 |  Abstract »  |  Full Text »  |  PDF »

Positive and Negative Regulation of Nuclear Factor-{kappa}B-mediated Transcription by I{kappa}B-{zeta}, an Inducible Nuclear Protein.

M. Motoyama, S. Yamazaki, A. Eto-Kimura, K. Takeshige, and T. Muta (2005)
J. Biol. Chem. 280, 7444-7451
 |  Abstract »  |  Full Text »  |  PDF »

Negative Regulation of JNK Signaling by the Tumor Suppressor CYLD.

W. Reiley, M. Zhang, and S.-C. Sun (2004)
J. Biol. Chem. 279, 55161-55167
 |  Abstract »  |  Full Text »  |  PDF »

Adipocyte differentiation induces dynamic changes in NF-{kappa}B expression and activity.

A. H. Berg, Y. Lin, M. P. Lisanti, and P. E. Scherer (2004)
Am J Physiol Endocrinol Metab 287, E1178-E1188
 |  Abstract »  |  Full Text »  |  PDF »

NF-{kappa}B Regulates Expression of the MHC Class I-Related Chain A Gene in Activated T Lymphocytes.

L. L. Molinero, M. B. Fuertes, M. V. Girart, L. Fainboim, G. A. Rabinovich, M. A. Costas, and N. W. Zwirner (2004)
J. Immunol. 173, 5583-5590
 |  Abstract »  |  Full Text »  |  PDF »

Dobutamine Inhibits Phorbol-Myristate-Acetate-Induced Activation of Nuclear Factor-{kappa}B in Human T Lymphocytes In Vitro.

T. Loop, T. Bross, M. Humar, A. Hoetzel, R. Schmidt, H. L. Pahl, K. K. Geiger, and B. H. J. Pannen (2004)
Anesth. Analg. 99, 1508-1515
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of Phospholipid-hydroperoxide Glutathione Peroxidase in Human Dermal Fibroblasts Abrogates UVA Irradiation-induced Expression of Interstitial Collagenase/Matrix Metalloproteinase-1 by Suppression of Phosphatidylcholine Hydroperoxide-mediated NF{kappa}B Activation and Interleukin-6 Release.

J. Wenk, J. Schuller, C. Hinrichs, T. Syrovets, N. Azoitei, M. Podda, M. Wlaschek, P. Brenneisen, L.-A. Schneider, A. Sabiwalsky, et al. (2004)
J. Biol. Chem. 279, 45634-45642
 |  Abstract »  |  Full Text »  |  PDF »

Oscillations in NF-{kappa}B Signaling Control the Dynamics of Gene Expression.

D. E. Nelson, A. E. C. Ihekwaba, M. Elliott, J. R. Johnson, C. A. Gibney, B. E. Foreman, G. Nelson, V. See, C. A. Horton, D. G. Spiller, et al. (2004)
Science 306, 704-708
 |  Abstract »  |  Full Text »  |  PDF »

Human Polynucleotide Phosphorylase (hPNPaseold-35): A Potential Link between Aging and Inflammation.

D. Sarkar, I. V. Lebedeva, L. Emdad, D.-c. Kang, A. S. Baldwin Jr., and P. B. Fisher (2004)
Cancer Res. 64, 7473-7478
 |  Abstract »  |  Full Text »  |  PDF »

Expression of MHC-{beta} and MCT1 in cardiac muscle after exercise training in myocardial-infarcted rats.

T. Hashimoto, N. Kambara, R. Nohara, M. Yazawa, and S. Taguchi (2004)
J Appl Physiol 97, 843-851
 |  Abstract »  |  Full Text »  |  PDF »

NF-{kappa}B Is Essential for Induction of CYLD, the Negative Regulator of NF-{kappa}B: EVIDENCE FOR A NOVEL INDUCIBLE AUTOREGULATORY FEEDBACK PATHWAY.

H. Jono, J. H. Lim, L.-F. Chen, H. Xu, E. Trompouki, Z. K. Pan, G. Mosialos, and J.-D. Li (2004)
J. Biol. Chem. 279, 36171-36174
 |  Abstract »  |  Full Text »  |  PDF »

I{kappa}B Kinase Is an Essential Component of the Tpl2 Signaling Pathway.

M. Waterfield, W. Jin, W. Reiley, M. Zhang, and S.-C. Sun (2004)
Mol. Cell. Biol. 24, 6040-6048
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Constitutive p50/c-Rel Activity via Proteasome Inhibitor-Resistant I{kappa}B{alpha} Degradation in B Cells.

S. O'Connor, S. D. Shumway, I. J. Amanna, C. E. Hayes, and S. Miyamoto (2004)
Mol. Cell. Biol. 24, 4895-4908
 |  Abstract »  |  Full Text »  |  PDF »

CD28 Costimulation Controls Histone Hyperacetylation of the Interleukin 5 Gene Locus in Developing Th2 Cells.

M. Inami, M. Yamashita, Y. Tenda, A. Hasegawa, M. Kimura, K. Hashimoto, N. Seki, M. Taniguchi, and T. Nakayama (2004)
J. Biol. Chem. 279, 23123-23133
 |  Abstract »  |  Full Text »  |  PDF »

Identification of an Autoregulatory Feedback Pathway Involving Interleukin-1{alpha} in Induction of Constitutive NF-{kappa}B Activation in Pancreatic Cancer Cells.

J. Niu, Z. Li, B. Peng, and P. J. Chiao (2004)
J. Biol. Chem. 279, 16452-16462
 |  Abstract »  |  Full Text »  |  PDF »

A p105-based Inhibitor Broadly Represses NF-{kappa}B Activities.

D. Fu, M. Kobayashi, and L. Lin (2004)
J. Biol. Chem. 279, 12819-12826
 |  Abstract »  |  Full Text »  |  PDF »

Kinase RIP3 Is Dispensable for Normal NF-{kappa}Bs, Signaling by the B-Cell and T-Cell Receptors, Tumor Necrosis Factor Receptor 1, and Toll-Like Receptors 2 and 4.

K. Newton, X. Sun, and V. M. Dixit (2004)
Mol. Cell. Biol. 24, 1464-1469
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of Rel/Nuclear Factor-{kappa}B Transcription Factors in Keratinocyte Senescence.

D. Bernard, K. Gosselin, D. Monte, C. Vercamer, F. Bouali, A. Pourtier, B. Vandenbunder, and C. Abbadie (2004)
Cancer Res. 64, 472-481
 |  Abstract »  |  Full Text »  |  PDF »

Persistent Activation of Nuclear Factor-{kappa}B Signaling Pathway in Severe Uncontrolled Asthma.

R. Gagliardo, P. Chanez, M. Mathieu, A. Bruno, G. Costanzo, C. Gougat, I. Vachier, J. Bousquet, G. Bonsignore, and A. M. Vignola (2003)
Am. J. Respir. Crit. Care Med. 168, 1190-1198
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Developing B Cell Survival by RelA-Containing NF-{kappa}B Complexes.

M. Prendes, Y. Zheng, and A. A. Beg (2003)
J. Immunol. 171, 3963-3969
 |  Abstract »  |  Full Text »  |  PDF »

Apparently Normal Tumor Necrosis Factor Receptor 1 Signaling in the Absence of the Silencer of Death Domains.

R. Endres, G. Hacker, I. Brosch, and K. Pfeffer (2003)
Mol. Cell. Biol. 23, 6609-6617
 |  Abstract »  |  Full Text »  |  PDF »

Differential Phosphorylation of the Signal-responsive Domain of I{kappa}B{alpha} and I{kappa}B{beta} by I{kappa}B Kinases.

C. Wu and S. Ghosh (2003)
J. Biol. Chem. 278, 31980-31987
 |  Abstract »  |  Full Text »  |  PDF »

Abdominal irradiation increases inflammatory cytokine expression and activates NF-{kappa}B in rat ileal muscularis layer.

C. Linard, A. Ropenga, M. C. Vozenin-Brotons, A. Chapel, and D. Mathe (2003)
Am J Physiol Gastrointest Liver Physiol 285, G556-G565
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of NF-{kappa}B essentially contributes to arsenic-induced apoptosis.

S. Mathas, A. Lietz, M. Janz, M. Hinz, F. Jundt, C. Scheidereit, K. Bommert, and B. Dorken (2003)
Blood 102, 1028-1034
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Basal Expression of I{kappa}B{alpha} Is Controlled by the Mammalian Transcriptional Repressor RBP-J (CBF1) and Its Activator Notch1.

F. Oakley, J. Mann, R. G. Ruddell, J. Pickford, G. Weinmaster, and D. A. Mann (2003)
J. Biol. Chem. 278, 24359-24370
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X-ray Crystal Structure of an I{kappa}B{beta}{middle dot}NF-{kappa}B p65 Homodimer Complex.

S. Malek, D.-B. Huang, T. Huxford, S. Ghosh, and G. Ghosh (2003)
J. Biol. Chem. 278, 23094-23100
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{kappa}B-Ras Binds to the Unique Insert within the Ankyrin Repeat Domain of I{kappa}B{beta} and Regulates Cytoplasmic Retention of I{kappa}B{beta}{middle dot}NF-{kappa}B Complexes.

Y. Chen, J. Wu, and G. Ghosh (2003)
J. Biol. Chem. 278, 23101-23106
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I{kappa}B-{zeta}, a new anti-inflammatory nuclear protein induced by lipopolysaccharide, is a negative regulator for nuclear factor-{kappa}B.

T. Muta, S. Yamazaki, A. Eto, M. Motoyama, and K. Takeshige (2003)
Innate Immunity 9, 187-191
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Hypertonicity Inhibits Lipopolysaccharide-Induced Nitric Oxide Synthase Expression in Smooth Muscle Cells by Inhibiting Nuclear Factor {kappa}B.

S. C. Pingle, J. F. Sanchez, D. M. Hallam, A. L. Williamson, S. B. Maggirwar, and V. Ramkumar (2003)
Mol. Pharmacol. 63, 1238-1247
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RANK Ligand-induced Elevation of Cytosolic Ca2+ Accelerates Nuclear Translocation of Nuclear Factor kappa B in Osteoclasts.

S. V. Komarova, M. F. Pilkington, A. F. Weidema, S. J. Dixon, and S. M. Sims (2003)
J. Biol. Chem. 278, 8286-8293
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Tumor Necrosis Factor-regulated Biphasic Activation of NF-kappa B Is Required for Cytokine-induced Loss of Skeletal Muscle Gene Products.

K. J. Ladner, M. A. Caligiuri, and D. C. Guttridge (2003)
J. Biol. Chem. 278, 2294-2303
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Post-activation Turn-off of NF-kappa B-dependent Transcription Is Regulated by Acetylation of p65.

R. Kiernan, V. Bres, R. W. M. Ng, M.-P. Coudart, S. El Messaoudi, C. Sardet, D.-Y. Jin, S. Emiliani, and M. Benkirane (2003)
J. Biol. Chem. 278, 2758-2766
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A Requirement of Nuclear Factor-kappa B Activation in Fear-potentiated Startle.

S.-H. Yeh, C.-H. Lin, C.-F. Lee, and P.-W. Gean (2002)
J. Biol. Chem. 277, 46720-46729
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Low Intracellular Zinc Impairs the Translocation of Activated NF-kappa B to the Nuclei in Human Neuroblastoma IMR-32 Cells.

G. G. Mackenzie, M. P. Zago, C. L. Keen, and P. I. Oteiza (2002)
J. Biol. Chem. 277, 34610-34617
 |  Abstract »  |  Full Text »  |  PDF »

NF-{kappa}B Activation in Light-Induced Retinal Degeneration in a Mouse Model.

T. Wu, Y. Chen, S. K. S. Chiang, and M. O. M. Tso (2002)
Invest. Ophthalmol. Vis. Sci. 43, 2834-2840
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Dehydroepiandrosterone Modulates Nuclear Factor-{kappa}B Activation in Hippocampus of Diabetic Rats.

M. Aragno, R. Mastrocola, E. Brignardello, M. Catalano, G. Robino, R. Manti, M. Parola, O. Danni, and G. Boccuzzi (2002)
Endocrinology 143, 3250-3258
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Glucocorticoid-Mediated Suppression of Cytokine-Induced Matrix Metalloproteinase-9 Expression in Rat Mesangial Cells: Involvement of Nuclear Factor-{kappa}B and Ets Transcription Factors.

W. Eberhardt, M. Schulze, C. Engels, E. Klasmeier, and J. Pfeilschifter (2002)
Mol. Endocrinol. 16, 1752-1766
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NF-{kappa}B Family of Transcription Factors: Central Regulators of Innate and Adaptive Immune Functions.

J. Caamano and C. A. Hunter (2002)
Clin. Microbiol. Rev. 15, 414-429
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Characterization of the Nuclear Import and Export Functions of Ikappa Bepsilon.

S.-H. Lee and M. Hannink (2002)
J. Biol. Chem. 277, 23358-23366
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Macrophage-Inflammatory Protein-3{alpha} Gene Expression by TNF-Dependent NF-{kappa}B Activation.

S. Sugita, T. Kohno, K. Yamamoto, Y. Imaizumi, H. Nakajima, T. Ishimaru, and T. Matsuyama (2002)
J. Immunol. 168, 5621-5628
 |  Abstract »  |  Full Text »  |  PDF »

DNA Binding-Independent Induction of I{kappa}B{alpha} Gene Transcription by PPAR{alpha}.

P. Delerive, K. De Bosscher, W. Vanden Berghe, J.-C. Fruchart, G. Haegeman, and B. Staels (2002)
Mol. Endocrinol. 16, 1029-1039
 |  Abstract »  |  Full Text »  |  PDF »

Multi-parameter analysis of the kinetics of NF-{kappa}B signalling and transcription in single living cells.

G. Nelson, L. Paraoan, D. G. Spiller, G. J. C. Wilde, M. A. Browne, P. K. Djali, J. F. Unitt, E. Sullivan, E. Floettmann, and M. R. H. White (2002)
J. Cell Sci. 115, 1137-1148
 |  Abstract »  |  Full Text »  |  PDF »

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