Science 19 March 1993: Vol. 259. no. 5102, pp. 1742 - 1745 DOI: 10.1126/science.8456301

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Articles

Race between Retroviral Spread and CD4+ T-Cell Response Determines the Outcome of Acute Friend Virus Infection.

R. Pike, A. Filby, M. J.-Y. Ploquin, U. Eksmond, R. Marques, I. Antunes, K. Hasenkrug, and G. Kassiotis (2009)
J. Virol. 83, 11211-11222
 |  Abstract »  |  Full Text »  |  PDF »

How Diverse--CD4 Effector T Cells and their Functions.

Y. Y. Wan and R. A. Flavell (2009)
J Mol Cell Biol 1, 20-36
 |  Abstract »  |  Full Text »  |  PDF »

Vaccinia virus inoculation in sites of allergic skin inflammation elicits a vigorous cutaneous IL-17 response.

M. K. Oyoshi, A. Elkhal, L. Kumar, J. E. Scott, S. Koduru, R. He, D. Y. M. Leung, M. D. Howell, H. C. Oettgen, G. F. Murphy, et al. (2009)
PNAS 106, 14954-14959
 |  Abstract »  |  Full Text »  |  PDF »

C3 Promotes Expansion of CD8+ and CD4+ T Cells in a Listeria monocytogenes Infection.

Y. Nakayama, S.-I. Kim, E. H. Kim, J. D. Lambris, M. Sandor, and M. Suresh (2009)
J. Immunol. 183, 2921-2931
 |  Abstract »  |  Full Text »  |  PDF »

Programming tumor-reactive effector memory CD8+ T cells in vitro obviates the requirement for in vivo vaccination.

C. A. Klebanoff, Z. Yu, L. N. Hwang, D. C. Palmer, L. Gattinoni, and N. P. Restifo (2009)
Blood 114, 1776-1783
 |  Abstract »  |  Full Text »  |  PDF »

Differential Interferon Responses Enhance Viral Epitope Generation by Myocardial Immunoproteasomes in Murine Enterovirus Myocarditis.

S. Jakel, U. Kuckelkorn, G. Szalay, M. Plotz, K. Textoris-Taube, E. Opitz, K. Klingel, S. Stevanovic, R. Kandolf, K. Kotsch, et al. (2009)
Am. J. Pathol. 175, 510-518
 |  Abstract »  |  Full Text »  |  PDF »

IL-17 and IFN-{gamma} Mediate the Elicitation of Contact Hypersensitivity Responses by Different Mechanisms and Both Are Required for Optimal Responses.

D. He, L. Wu, H. K. Kim, H. Li, C. A. Elmets, and H. Xu (2009)
J. Immunol. 183, 1463-1470
 |  Abstract »  |  Full Text »  |  PDF »

Murine Gammaherpesvirus 68 Infection of IFN{gamma} Unresponsive Mice: A Small Animal Model for Gammaherpesvirus-Associated B-Cell Lymphoproliferative Disease.

K. S. Lee, S. D. Groshong, C. D. Cool, B. K. Kleinschmidt-DeMasters, and L. F. van Dyk (2009)
Cancer Res. 69, 5481-5489
 |  Abstract »  |  Full Text »  |  PDF »

Endotoxin Augmented Antigen-Induced Th1 Cell Trafficking Amplifies Airway Neutrophilic Inflammation.

Z. Mikhak, A. Farsidjani, and A. D. Luster (2009)
J. Immunol. 182, 7946-7956
 |  Abstract »  |  Full Text »  |  PDF »

Type I and Type II Interferons Inhibit the Translation of Murine Norovirus Proteins.

H. Changotra, Y. Jia, T. N. Moore, G. Liu, S. M. Kahan, S. V. Sosnovtsev, and S. M. Karst (2009)
J. Virol. 83, 5683-5692
 |  Abstract »  |  Full Text »  |  PDF »

Critical Roles of NK and CD8+ T Cells in Central Nervous System Listeriosis.

T. Hayashi, S. Nagai, H. Fujii, Y. Baba, E. Ikeda, T. Kawase, and S. Koyasu (2009)
J. Immunol. 182, 6360-6368
 |  Abstract »  |  Full Text »  |  PDF »

Tristetraprolin Mediates Interferon-{gamma} mRNA Decay.

R. L. Ogilvie, J. R. SternJohn, B. Rattenbacher, I. A. Vlasova, D. A. Williams, H. H. Hau, P. J. Blackshear, and P. R. Bohjanen (2009)
J. Biol. Chem. 284, 11216-11223
 |  Abstract »  |  Full Text »  |  PDF »

Gamma Interferon-Induced Interferon Regulatory Factor 1-Dependent Antiviral Response Inhibits Vaccinia Virus Replication in Mouse but Not Human Fibroblasts.

M. Trilling, V. T. K. Le, A. Zimmermann, H. Ludwig, K. Pfeffer, G. Sutter, G. L. Smith, and H. Hengel (2009)
J. Virol. 83, 3684-3695
 |  Abstract »  |  Full Text »  |  PDF »

Control of T helper cell differentiation through cytokine receptor inclusion in the immunological synapse.

R. A. Maldonado, M. A. Soriano, L. C. Perdomo, K. Sigrist, D. J. Irvine, T. Decker, and L. H. Glimcher (2009)
J. Exp. Med. 206, 877-892
 |  Abstract »  |  Full Text »  |  PDF »

Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses.

T. H. Mogensen (2009)
Clin. Microbiol. Rev. 22, 240-273
 |  Abstract »  |  Full Text »  |  PDF »

Oral Live Vaccine Strain-Induced Protective Immunity against Pulmonary Francisella tularensis Challenge Is Mediated by CD4+ T Cells and Antibodies, Including Immunoglobulin A.

H. J. Ray, Y. Cong, A. K. Murthy, D. M. Selby, K. E. Klose, J. R. Barker, M. N. Guentzel, and B. P. Arulanandam (2009)
Clin. Vaccine Immunol. 16, 444-452
 |  Abstract »  |  Full Text »  |  PDF »

Vaccinia Virus-Mediated Inhibition of Type I Interferon Responses Is a Multifactorial Process Involving the Soluble Type I Interferon Receptor B18 and Intracellular Components.

Z. Waibler, M. Anzaghe, T. Frenz, A. Schwantes, C. Pohlmann, H. Ludwig, M. Palomo-Otero, A. Alcami, G. Sutter, and U. Kalinke (2009)
J. Virol. 83, 1563-1571
 |  Abstract »  |  Full Text »  |  PDF »

Production of protective gamma interferon by natural killer cells during early mouse hepatitis virus infection.

G. Thirion and J.-P. Coutelier (2009)
J. Gen. Virol. 90, 442-447
 |  Abstract »  |  Full Text »  |  PDF »

Colony-Stimulating Factor-1-Dependent Macrophage Functions Regulate the Maternal Decidua Immune Responses against Listeria monocytogenes Infections during Early Gestation in Mice.

X. Qiu, L. Zhu, and J. W. Pollard (2009)
Infect. Immun. 77, 85-97
 |  Abstract »  |  Full Text »  |  PDF »

A critical link between Toll-like receptor 3 and type II interferon signaling pathways in antiviral innate immunity.

H. Negishi, T. Osawa, K. Ogami, X. Ouyang, S. Sakaguchi, R. Koshiba, H. Yanai, Y. Seko, H. Shitara, K. Bishop, et al. (2008)
PNAS 105, 20446-20451
 |  Abstract »  |  Full Text »  |  PDF »

Role of T Cells in Virus Control and Disease after Infection with Pneumonia Virus of Mice.

S. Frey, C. D. Krempl, A. Schmitt-Graff, and S. Ehl (2008)
J. Virol. 82, 11619-11627
 |  Abstract »  |  Full Text »  |  PDF »

Natural Killer Cell Accumulation in Tumors Is Dependent on IFN-{gamma} and CXCR3 Ligands.

M. Wendel, I. E. Galani, E. Suri-Payer, and A. Cerwenka (2008)
Cancer Res. 68, 8437-8445
 |  Abstract »  |  Full Text »  |  PDF »

TLR4-induced IFN-{gamma} production increases TLR2 sensitivity and drives Gram-negative sepsis in mice.

S. Spiller, G. Elson, R. Ferstl, S. Dreher, T. Mueller, M. Freudenberg, B. Daubeuf, H. Wagner, and C. J. Kirschning (2008)
J. Exp. Med. 205, 1747-1754
 |  Abstract »  |  Full Text »  |  PDF »

Differential Effects of the Type I Interferons {alpha}4, {beta}, and {epsilon} on Antiviral Activity and Vaccine Efficacy.

S. L. Day, I. A. Ramshaw, A. J. Ramsay, and C. Ranasinghe (2008)
J. Immunol. 180, 7158-7166
 |  Abstract »  |  Full Text »  |  PDF »

The orthopoxvirus type I IFN binding protein is essential for virulence and an effective target for vaccination.

R.-H. Xu, M. Cohen, Y. Tang, E. Lazear, J. C. Whitbeck, R. J. Eisenberg, G. H. Cohen, and L. J. Sigal (2008)
J. Exp. Med. 205, 981-992
 |  Abstract »  |  Full Text »  |  PDF »

SOCS-1 Protects against Chlamydia pneumoniae-Induced Lethal Inflammation but Hampers Effective Bacterial Clearance.

T. Yang, P. Stark, K. Janik, H. Wigzell, and M. E. Rottenberg (2008)
J. Immunol. 180, 4040-4049
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Human NK Cells by the Bacterial Pathogen-Associated Molecular Pattern Muramyl Dipeptide.

V. Athie-Morales, G. M. O'Connor, and C. M. Gardiner (2008)
J. Immunol. 180, 4082-4089
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: T-bet and IL-27R Are Critical for In Vivo IFN-{gamma} Production by CD8 T Cells during Infection.

K. D. Mayer, K. Mohrs, W. Reiley, S. Wittmer, J. E. Kohlmeier, J. E. Pearl, A. M. Cooper, L. L. Johnson, D. L. Woodland, and M. Mohrs (2008)
J. Immunol. 180, 693-697
 |  Abstract »  |  Full Text »  |  PDF »

CD62L (L-Selectin) Down-Regulation Does Not Affect Memory T Cell Distribution but Failure to Shed Compromises Anti-Viral Immunity.

H. Richards, M. P. Longhi, K. Wright, A. Gallimore, and A. Ager (2008)
J. Immunol. 180, 198-206
 |  Abstract »  |  Full Text »  |  PDF »

Importance of T Cells, Gamma Interferon, and Tumor Necrosis Factor in Immune Control of the Rapid Grower Mycobacterium abscessus in C57BL/6 Mice.

M. Rottman, E. Catherinot, P. Hochedez, J.-F. Emile, J.-L. Casanova, J.-L. Gaillard, and C. Soudais (2007)
Infect. Immun. 75, 5898-5907
 |  Abstract »  |  Full Text »  |  PDF »

Extensive Characterization of IFN-Induced GTPases mGBP1 to mGBP10 Involved in Host Defense.

D. Degrandi, C. Konermann, C. Beuter-Gunia, A. Kresse, J. Wurthner, S. Kurig, S. Beer, and K. Pfeffer (2007)
J. Immunol. 179, 7729-7740
 |  Abstract »  |  Full Text »  |  PDF »

Spleen B cells from BALB/c are more prone to activation than spleen B cells from C57BL/6 mice during a secondary immune response to cruzipain.

A. Pellegrini, N. Guinazu, M. P. Aoki, I. C. Calero, E. A. Carrera-Silva, N. Girones, M. Fresno, and S. Gea (2007)
Int. Immunol. 19, 1395-1402
 |  Abstract »  |  Full Text »  |  PDF »

Divergent roles of IFNs in the sensitization to endotoxin shock by lactate dehydrogenase-elevating virus.

T. Le-Thi-Phuong, L. Dumoutier, J.-C. Renauld, J. Van Snick, and J.-P. Coutelier (2007)
Int. Immunol. 19, 1303-1311
 |  Abstract »  |  Full Text »  |  PDF »

Regional IFN{gamma} expression is insufficient for efficacious control of food-borne bacterial pathogens at the gut epithelial barrier.

N. Gajendran, H.-W. Mittrucker, K. Bordasch, E. Heinemann, M. Koch, and S. H. E. Kaufmann (2007)
Int. Immunol. 19, 1075-1081
 |  Abstract »  |  Full Text »  |  PDF »

Role of Direct Effects of IFN-{gamma} on T Cells in the Regulation of CD8 T Cell Homeostasis.

K. Tewari, Y. Nakayama, and M. Suresh (2007)
J. Immunol. 179, 2115-2125
 |  Abstract »  |  Full Text »  |  PDF »

Cytolysin-Dependent Escape of the Bacterium from the Phagosome Is Required but Not Sufficient for Induction of the Th1 Immune Response against Listeria monocytogenes Infection: Distinct Role of Listeriolysin O Determined by Cytolysin Gene Replacement.

H. Hara, I. Kawamura, T. Nomura, T. Tominaga, K. Tsuchiya, and M. Mitsuyama (2007)
Infect. Immun. 75, 3791-3801
 |  Abstract »  |  Full Text »  |  PDF »

IFN-{gamma}-Induced Chemokines Synergize with Pertussis Toxin to Promote T Cell Entry to the Central Nervous System.

J. M. Millward, M. Caruso, I. L. Campbell, J. Gauldie, and T. Owens (2007)
J. Immunol. 178, 8175-8182
 |  Abstract »  |  Full Text »  |  PDF »

Poxvirus-Encoded Gamma Interferon Binding Protein Dampens the Host Immune Response to Infection.

I. G. Sakala, G. Chaudhri, R. M. Buller, A. A. Nuara, H. Bai, N. Chen, and G. Karupiah (2007)
J. Virol. 81, 3346-3353
 |  Abstract »  |  Full Text »  |  PDF »

Protective role of IFN-{gamma} in collagen-induced arthritis conferred by inhibition of mycobacteria-induced granulocyte chemotactic protein-2 production.

H. Kelchtermans, S. Struyf, B. De Klerck, T. Mitera, M. Alen, L. Geboes, M. Van Balen, C. Dillen, W. Put, C. Gysemans, et al. (2007)
J. Leukoc. Biol. 81, 1044-1053
 |  Abstract »  |  Full Text »  |  PDF »

Loss of blood-brain barrier integrity in the spinal cord is common to experimental allergic encephalomyelitis in knockout mouse models.

M. J. Fabis, G. S. Scott, R. B. Kean, H. Koprowski, and D. C. Hooper (2007)
PNAS 104, 5656-5661
 |  Abstract »  |  Full Text »  |  PDF »

Induction of a Th1 Response from Th2-Polarized T Cells by Activated Dendritic Cells: Dependence on TCR:Peptide-MHC Interaction, ICAM-1, IL-12, and IFN-{gamma}.

S. Radhakrishnan, K. R. Wiehagen, V. Pulko, V. Van Keulen, W. A. Faubion, K. L. Knutson, and L. R. Pease (2007)
J. Immunol. 178, 3583-3592
 |  Abstract »  |  Full Text »  |  PDF »

Invariant NKT cells sustain specific B cell responses and memory.

G. Galli, P. Pittoni, E. Tonti, C. Malzone, Y. Uematsu, M. Tortoli, D. Maione, G. Volpini, O. Finco, S. Nuti, et al. (2007)
PNAS 104, 3984-3989
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: IFN-{gamma}-Producing CD4 T Lymphocytes Mediate Spore-Induced Immunity to Capsulated Bacillus anthracis.

I. J. Glomski, J.-P. Corre, M. Mock, and P. L. Goossens (2007)
J. Immunol. 178, 2646-2650
 |  Abstract »  |  Full Text »  |  PDF »

High IFN-{gamma} Production of Individual CD8 T Lymphocytes Is Controlled by CD152 (CTLA-4).

P. Pandiyan, J. K. E. Hegel, M. Krueger, D. Quandt, and M. C. Brunner-Weinzierl (2007)
J. Immunol. 178, 2132-2140
 |  Abstract »  |  Full Text »  |  PDF »

Expression of the p60 Autolysin Enhances NK Cell Activation and Is Required for Listeria monocytogenes Expansion in IFN-{gamma}-Responsive Mice.

J. Humann, R. Bjordahl, K. Andreasen, and L. L. Lenz (2007)
J. Immunol. 178, 2407-2414
 |  Abstract »  |  Full Text »  |  PDF »

Dendritic cells suppress IgE production in B cells.

K. Obayashi, T. Doi, and S. Koyasu (2007)
Int. Immunol. 19, 217-226
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-{gamma} and Tumor Necrosis Factor-{alpha} Regulate Amyloid-{beta} Plaque Deposition and {beta}-Secretase Expression in Swedish Mutant APP Transgenic Mice.

M. Yamamoto, T. Kiyota, M. Horiba, J. L. Buescher, S. M. Walsh, H. E. Gendelman, and T. Ikezu (2007)
Am. J. Pathol. 170, 680-692
 |  Abstract »  |  Full Text »  |  PDF »

Early Resolution of Herpes Simplex Virus Type 2 Infection of the Murine Genital Tract Involves Stimulation of Genital Parenchymal Cells by Gamma Interferon.

M. D. Bird, C.-F. Chu, A. J. Johnson, and G. N. Milligan (2007)
J. Virol. 81, 423-426
 |  Abstract »  |  Full Text »  |  PDF »

CD8+ T cell-mediated immune responses in West Nile virus (Sarafend strain) encephalitis are independent of gamma interferon.

Y. Wang, M. Lobigs, E. Lee, A. Koskinen, and A. Mullbacher (2006)
J. Gen. Virol. 87, 3599-3609
 |  Abstract »  |  Full Text »  |  PDF »

Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction.

K. Sato, A. Suematsu, K. Okamoto, A. Yamaguchi, Y. Morishita, Y. Kadono, S. Tanaka, T. Kodama, S. Akira, Y. Iwakura, et al. (2006)
J. Exp. Med. 203, 2673-2682
 |  Abstract »  |  Full Text »  |  PDF »

H2-M3-Restricted T Cells Participate in the Priming of Antigen-Specific CD4+ T Cells.

M. T. Chow, S. Dhanji, J. Cross, P. Johnson, and H.-S. Teh (2006)
J. Immunol. 177, 5098-5104
 |  Abstract »  |  Full Text »  |  PDF »

Induced Expression of Murine {gamma}2a by CD40 Ligation Independently of IFN-{gamma}.

J. T. Collins, J. Shi, B. E. Burrell, D. K. Bishop, and W. A. Dunnick (2006)
J. Immunol. 177, 5414-5419
 |  Abstract »  |  Full Text »  |  PDF »

Infection with Syphacia obvelata (Pinworm) Induces Protective Th2 Immune Responses and Influences Ovalbumin-Induced Allergic Reactions..

C. Michels, P. Goyal, N. Nieuwenhuizen, and F. Brombacher (2006)
Infect. Immun. 74, 5926-5932
 |  Abstract »  |  Full Text »  |  PDF »

IFN-{gamma} and T-bet Expression in Human Dendritic Cells from Normal Donors and Cancer Patients Is Controlled through Mechanisms Involving ERK-1/2-Dependent and IL-12-Independent Pathways.

H. Li, W. Wojciechowski, C. Dell'Agnola, N. E. Lopez, and I. Espinoza-Delgado (2006)
J. Immunol. 177, 3554-3563
 |  Abstract »  |  Full Text »  |  PDF »

Proprotein convertase furin is preferentially expressed in T helper 1 cells and regulates interferon gamma.

M. Pesu, L. Muul, Y. Kanno, and J. J. O'Shea (2006)
Blood 108, 983-985
 |  Abstract »  |  Full Text »  |  PDF »

STAT1 Regulates IFN-{alpha}beta- and IFN-{gamma}-Dependent Control of Infection with Chlamydia pneumoniae by Nonhemopoietic Cells..

A. G. Rothfuchs, C. Trumstedt, F. Mattei, G. Schiavoni, A. Hidmark, H. Wigzell, and M. E. Rottenberg (2006)
J. Immunol. 176, 6982-6990
 |  Abstract »  |  Full Text »  |  PDF »

MyD88-Dependent IFN-{gamma} Production by NK Cells Is Key for Control of Legionella pneumophila Infection.

R. Sporri, N. Joller, U. Albers, H. Hilbi, and A. Oxenius (2006)
J. Immunol. 176, 6162-6171
 |  Abstract »  |  Full Text »  |  PDF »

Deleterious Role of IFN{gamma} in a Toxic Model of Central Nervous System Demyelination.

P. Mana, D. Linares, S. Fordham, M. Staykova, and D. Willenborg (2006)
Am. J. Pathol. 168, 1464-1473
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of the Mouse IFN-{lambda} Ligand-Receptor System: IFN-{lambda}s Exhibit Antitumor Activity against B16 Melanoma..

A. Lasfar, A. Lewis-Antes, S. V. Smirnov, S. Anantha, W. Abushahba, B. Tian, K. Reuhl, H. Dickensheets, F. Sheikh, R. P. Donnelly, et al. (2006)
Cancer Res. 66, 4468-4477
 |  Abstract »  |  Full Text »  |  PDF »

Self-Limitation of Th1-Mediated Inflammation by IFN-{gamma}..

M. Feuerer, K. Eulenburg, C. Loddenkemper, A. Hamann, and J. Huehn (2006)
J. Immunol. 176, 2857-2863
 |  Abstract »  |  Full Text »  |  PDF »

Dissection of ESAT-6 System 1 of Mycobacterium tuberculosis and Impact on Immunogenicity and Virulence.

P. Brodin, L. Majlessi, L. Marsollier, M. I. de Jonge, D. Bottai, C. Demangel, J. Hinds, O. Neyrolles, P. D. Butcher, C. Leclerc, et al. (2006)
Infect. Immun. 74, 88-98
 |  Abstract »  |  Full Text »  |  PDF »

Gamma Interferon Blocks Gammaherpesvirus Reactivation from Latency.

A. L. Steed, E. S. Barton, S. A. Tibbetts, D. L. Popkin, M. L. Lutzke, R. Rochford, and H. W. Virgin IV (2006)
J. Virol. 80, 192-200
 |  Abstract »  |  Full Text »  |  PDF »

Epitope-Specific Regulation of Immunoglobulin Class Switching in Mice Immunized with Malarial Merozoite Surface Proteins.

J. E. Tongren, P. H. Corran, W. Jarra, J. Langhorne, and E. M. Riley (2005)
Infect. Immun. 73, 8119-8129
 |  Abstract »  |  Full Text »  |  PDF »

Molecular and Cellular Basis of the Retrovirus Resistance in I/LnJ Mice.

L. K. Case, A. Purdy, and T. V. Golovkina (2005)
J. Immunol. 175, 7543-7549
 |  Abstract »  |  Full Text »  |  PDF »

Seeligeriolysin O, a protein toxin of Listeria seeligeri, stimulates macrophage cytokine production via Toll-like receptors in a profile different from that induced by other bacterial ligands.

Y. Ito, I. Kawamura, C. Kohda, K. Tsuchiya, T. Nomura, and M. Mitsuyama (2005)
Int. Immunol. 17, 1597-1606
 |  Abstract »  |  Full Text »  |  PDF »

Urocortin 2 Suppresses Host Resistance to Listeria monocytogenes Infection via Up-Regulation of Interleukin-10.

H. Sashinami, K. Kageyama, T. Suda, and A. Nakane (2005)
Endocrinology 146, 5003-5011
 |  Abstract »  |  Full Text »  |  PDF »

Lung infection with {gamma}-herpesvirus induces progressive pulmonary fibrosis in Th2-biased mice.

A. L. Mora, C. R. Woods, A. Garcia, J. Xu, M. Rojas, S. H. Speck, J. Roman, K. L. Brigham, and A. A. Stecenko (2005)
Am J Physiol Lung Cell Mol Physiol 289, L711-L721
 |  Abstract »  |  Full Text »  |  PDF »

Th1 Cytokines Are Essential for Placental Immunity to Listeria monocytogenes.

E. M. Barber, M. Fazzari, and J. W. Pollard (2005)
Infect. Immun. 73, 6322-6331
 |  Abstract »  |  Full Text »  |  PDF »

Expression of T-bet by CD4 T Cells Is Essential for Resistance to Salmonella Infection.

R. Ravindran, J. Foley, T. Stoklasek, L. H. Glimcher, and S. J. McSorley (2005)
J. Immunol. 175, 4603-4610
 |  Abstract »  |  Full Text »  |  PDF »

Type I Interferons Trigger Systemic, Partial Lymphocyte Activation in Response to Viral Infection.

M. Alsharifi, M. Lobigs, M. Regner, E. Lee, A. Koskinen, and A. Mullbacher (2005)
J. Immunol. 175, 4635-4640
 |  Abstract »  |  Full Text »  |  PDF »

Interferon function is not required for recovery from a secondary poxvirus infection.

V. Panchanathan, G. Chaudhri, and G. Karupiah (2005)
PNAS 102, 12921-12926
 |  Abstract »  |  Full Text »  |  PDF »

The Induction of a Type 1 Immune Response following a Trypanosoma brucei Infection Is MyD88 Dependent.

M. B. Drennan, B. Stijlemans, J. Van Den Abbeele, V. J. Quesniaux, M. Barkhuizen, F. Brombacher, P. De Baetselier, B. Ryffel, and S. Magez (2005)
J. Immunol. 175, 2501-2509
 |  Abstract »  |  Full Text »  |  PDF »

Impaired Virus Control and Severe CD8+ T-Cell-Mediated Immunopathology in Chimeric Mice Deficient in Gamma Interferon Receptor Expression on both Parenchymal and Hematopoietic Cells.

P. Henrichsen, C. Bartholdy, J. P. Christensen, and A. R. Thomsen (2005)
J. Virol. 79, 10073-10076
 |  Abstract »  |  Full Text »  |  PDF »

Relative Contributions of NK and CD8 T Cells to IFN-{gamma} Mediated Innate Immune Protection against Listeria monocytogenes.

R. E. Berg, E. Crossley, S. Murray, and J. Forman (2005)
J. Immunol. 175, 1751-1757
 |  Abstract »  |  Full Text »  |  PDF »

Simultaneous Th1-Type Cytokine Expression Is a Signature of Peritoneal CD4+ Lymphocytes Responding to Infection with Listeria monocytogenes.

M. M. Freeman and H. K. Ziegler (2005)
J. Immunol. 175, 394-403
 |  Abstract »  |  Full Text »  |  PDF »

The Functional Heterogeneity of Type 1 Effector T Cells in Response to Infection Is Related to the Potential for IFN-{gamma} Production.

K. D. Mayer, K. Mohrs, S. R. Crowe, L. L. Johnson, P. Rhyne, D. L. Woodland, and M. Mohrs (2005)
J. Immunol. 174, 7732-7739
 |  Abstract »  |  Full Text »  |  PDF »

Dengue Virus Type 2 Antagonizes IFN-{alpha} but Not IFN-{gamma} Antiviral Effect via Down-Regulating Tyk2-STAT Signaling in the Human Dendritic Cell.

L.-J. Ho, L.-F. Hung, C.-Y. Weng, W.-L. Wu, P. Chou, Y.-L. Lin, D.-M. Chang, T.-Y. Tai, and J.-H. Lai (2005)
J. Immunol. 174, 8163-8172
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Dynamic Regulation of IFN-{gamma} Signaling in Antigen-Specific CD8+ T Cells Responding to Infection.

J. S. Haring, G. A. Corbin, and J. T. Harty (2005)
J. Immunol. 174, 6791-6802
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Role for Innate IFNs in Determining Respiratory Syncytial Virus Immunopathology.

T. R. Johnson, S. E. Mertz, N. Gitiban, S. Hammond, R. LeGallo, R. K. Durbin, and J. E. Durbin (2005)
J. Immunol. 174, 7234-7241
 |  Abstract »  |  Full Text »  |  PDF »

Interference by interferons: Janus faces in vascular proliferative diseases.

R. Wessely (2005)
Cardiovasc Res 66, 433-443
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Re-evaluating the In Vivo Cytokine Responses of CD8+ T Cells during Primary and Secondary Viral Infections.

F. Liu and J. L. Whitton (2005)
J. Immunol. 174, 5936-5940
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-{gamma} acts directly on CD8+ T cells to increase their abundance during virus infection.

J. K. Whitmire, J. T. Tan, and J. L. Whitton (2005)
J. Exp. Med. 201, 1053-1059
 |  Abstract »  |  Full Text »  |  PDF »

Natural Killer Dendritic Cells Have Both Antigen Presenting and Lytic Function and in Response to CpG Produce IFN-{gamma} via Autocrine IL-12.

V. G. Pillarisetty, S. C. Katz, J. I. Bleier, A. B. Shah, and R. P. DeMatteo (2005)
J. Immunol. 174, 2612-2618
 |  Abstract »  |  Full Text »  |  PDF »

Reduced Local Growth and Spread but Preserved Pathogenicity of a {Delta}purC Mycobacterium tuberculosis Auxotrophic Mutant in Gamma Interferon Receptor-Deficient Mice after Aerosol Infection.

N. Brown, M. Jacobs, S. K. Parida, T. Botha, A. Santos, L. Fick, B. Gicquel, M. Jackson, V. Quesniaux, and B. Ryffel (2005)
Infect. Immun. 73, 666-670
 |  Abstract »  |  Full Text »  |  PDF »

Impairment of Host Resistance to Listeria monocytogenes Infection in Liver of db/db and ob/ob Mice.

S. Ikejima, S. Sasaki, H. Sashinami, F. Mori, Y. Ogawa, T. Nakamura, Y. Abe, K. Wakabayashi, T. Suda, and A. Nakane (2005)
Diabetes 54, 182-189
 |  Abstract »  |  Full Text »  |  PDF »

Gamma Interferon Does Not Enhance Clearance of Pseudomonas aeruginosa but Does Amplify a Proinflammatory Response in a Murine Model of Postseptic Immunosuppression.

E. D. Murphey, D. N. Herndon, and E. R. Sherwood (2004)
Infect. Immun. 72, 6892-6901
 |  Abstract »  |  Full Text »  |  PDF »

From The Cover: Induction of antiviral immunity requires Toll-like receptor signaling in both stromal and dendritic cell compartments.

A. Sato and A. Iwasaki (2004)
PNAS 101, 16274-16279
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Immunity and IFN-{gamma} Production during Listeria monocytogenes Infection in the Absence of T-bet.

S. S. Way and C. B. Wilson (2004)
J. Immunol. 173, 5918-5922
 |  Abstract »  |  Full Text »  |  PDF »

Prolonged Toll-Like Receptor Signaling by Mycobacterium tuberculosis and Its 19-Kilodalton Lipoprotein Inhibits Gamma Interferon-Induced Regulation of Selected Genes in Macrophages.

R. K. Pai, M. E. Pennini, A. A. R. Tobian, D. H. Canaday, W. H. Boom, and C. V. Harding (2004)
Infect. Immun. 72, 6603-6614
 |  Abstract »  |  Full Text »  |  PDF »

The Host Resistance Locus sst1 Controls Innate Immunity to Listeria monocytogenes Infection in Immunodeficient Mice.

V. Boyartchuk, M. Rojas, B.-S. Yan, O. Jobe, N. Hurt, D. M. Dorfman, D. E. Higgins, W. F. Dietrich, and I. Kramnik (2004)
J. Immunol. 173, 5112-5120
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of T cell development and activation by novel members of the Schlafen (slfn) gene family harbouring an RNA helicase-like motif.

P. Geserick, F. Kaiser, U. Klemm, S. H. E. Kaufmann, and J. Zerrahn (2004)
Int. Immunol. 16, 1535-1548
 |  Abstract »  |  Full Text »  |  PDF »

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