Science 26 February 1993: Vol. 259. no. 5099, pp. 1330 - 1335 DOI: 10.1126/science.8446902

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Articles

Thematic Review Series: Sphingolipids. Nuclear sphingolipids: metabolism and signaling.

R. W. Ledeen and G. Wu (2008)
J. Lipid Res. 49, 1176-1186
 |  Abstract »  |  Full Text »  |  PDF »

Requirements for nuclear localization of the Lsm2-8p complex and competition between nuclear and cytoplasmic Lsm complexes.

M. P. Spiller, M. A. M. Reijns, and J. D. Beggs (2007)
J. Cell Sci. 120, 4310-4320
 |  Abstract »  |  Full Text »  |  PDF »

Defining early steps in mRNA transport: mutant mRNA in myotonic dystrophy type I is blocked at entry into SC-35 domains.

K. P. Smith, M. Byron, C. Johnson, Y. Xing, and J. B. Lawrence (2007)
J. Cell Biol. 178, 951-964
 |  Abstract »  |  Full Text »  |  PDF »

The Lsm2-8 complex determines nuclear localization of the spliceosomal U6 snRNA.

M. P. Spiller, K.-L. Boon, M. A. M. Reijns, and J. D. Beggs (2007)
Nucleic Acids Res. 35, 923-929
 |  Abstract »  |  Full Text »  |  PDF »

Rapid, Diffusional Shuttling of Poly(A) RNA between Nuclear Speckles and the Nucleoplasm.

J. C. R. Politz, R. A. Tuft, K. V. Prasanth, N. Baudendistel, K. E. Fogarty, L. M. Lifshitz, J. Langowski, D. L. Spector, and T. Pederson (2006)
Mol. Biol. Cell 17, 1239-1249
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Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus.

R. R. E. Williams, V. Azuara, P. Perry, S. Sauer, M. Dvorkina, H. Jorgensen, J. Roix, P. McQueen, T. Misteli, M. Merkenschlager, et al. (2006)
J. Cell Sci. 119, 132-140
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The 4q subtelomere harboring the FSHD locus is specifically anchored with peripheral heterochromatin unlike most human telomeres.

R. Tam, K. P. Smith, and J. B. Lawrence (2004)
J. Cell Biol. 167, 269-279
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Poly(A)+ RNAs roam the cell nucleus and pass through speckle domains in transcriptionally active and inactive cells.

C. Molenaar, A. Abdulle, A. Gena, H. J. Tanke, and R. W. Dirks (2004)
J. Cell Biol. 165, 191-202
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Repositioning of Muscle-specific Genes Relative to the Periphery of SC-35 Domains during Skeletal Myogenesis.

P. T. Moen Jr., C. V. Johnson, M. Byron, L. S. Shopland, I. L. de la Serna, A. N. Imbalzano, and J. B. Lawrence (2004)
Mol. Biol. Cell 15, 197-206
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Clustering of multiple specific genes and gene-rich R-bands around SC-35 domains: evidence for local euchromatic neighborhoods.

L. S. Shopland, C. V. Johnson, M. Byron, J. McNeil, and J. B. Lawrence (2003)
J. Cell Biol. 162, 981-990
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Reduction of Target Gene Expression by a Modified U1 snRNA.

S. A. Beckley, P. Liu, M. L. Stover, S. I. Gunderson, A. C. Lichtler, and D. W. Rowe (2001)
Mol. Cell. Biol. 21, 2815-2825
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Mobility Within the Nucleus and Neighboring Cytosol Is a Key Feature of Prothymosin-{alpha}.

S. A. Enkemann, R. D. Ward, and S. L. Berger (2000)
J. Histochem. Cytochem. 48, 1341-1356
 |  Abstract »  |  Full Text »

Tracking COL1A1 RNA in Osteogenesis Imperfecta: Splice-defective Transcripts Initiate Transport from the Gene but Are Retained within the SC35 Domain.

C. Johnson, D. Primorac, M. McKinstry, J. McNeil, D. Rowe, and J. B. Lawrence (2000)
J. Cell Biol. 150, 417-432
 |  Abstract »  |  Full Text »  |  PDF »

Seeking Common Ground in Nuclear Complexity.

L. S. Shopland and J. B. Lawrence (2000)
J. Cell Biol. 150, F1-F4
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Nuclear Structure-Gene Expression Interrelationships: Implications for Aberrant Gene Expression in Cancer.

G. S. Stein, M. Montecino, A. J. van Wijnen, J. L. Stein, and J. B. Lian (2000)
Cancer Res. 60, 2067-2076
 |  Abstract »  |  Full Text »

Higher Levels of Organization in the Interphase Nucleus of Cycling and Differentiated Cells.

A. R. Leitch (2000)
Microbiol. Mol. Biol. Rev. 64, 138-152
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Omega speckles - a novel class of nuclear speckles containing hnRNPs associated with noncoding hsr-omega RNA in Drosophila.

K. Prasanth, T. Rajendra, A. Lal, and S. Lakhotia (2000)
J. Cell Sci. 113, 3485-3497
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Localization of poly(A)-binding protein 2 (PABP2) in nuclear speckles is independent of import into the nucleus and requires binding to poly(A) RNA.

A Calado and M Carmo-Fonseca (2000)
J. Cell Sci. 113, 2309-2318
 |  Abstract »  |  PDF »

Ex Vivo Desequestration of Plasmodium falciparum-Infected Erythrocytes from Human Placenta by Chondroitin Sulfate A.

J. Gysin, B. Pouvelle, N. Fievet, A. Scherf, and C. Lepolard (1999)
Infect. Immun. 67, 6596-6602
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Three-dimensional Visualization of Transcription Sites and Their Association with Splicing Factor–rich Nuclear Speckles.

X. Wei, S. Somanathan, J. Samarabandu, and R. Berezney (1999)
J. Cell Biol. 146, 543-558
 |  Abstract »  |  Full Text »  |  PDF »

Changing Views on the Nature of the Bacterial Cell: from Biochemistry to Cytology.

R. Losick and L. Shapiro (1999)
J. Bacteriol. 181, 4143-4145
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Differences in the Localization and Morphology of Chromosomes in the Human Nucleus.

J. A. Croft, J. M. Bridger, S. Boyle, P. Perry, P. Teague, and W. A. Bickmore (1999)
J. Cell Biol. 145, 1119-1131
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Intron-independent Association of Splicing Factors with Active Genes.

C. Jolly, C. Vourc'h, M. Robert-Nicoud, and R. I. Morimoto (1999)
J. Cell Biol. 145, 1133-1143
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Implications for interrelationships between nuclear architecture and control of gene expression under microgravity conditions.

G. S. STEIN, A. J. VAN WIJNEN, J. L. STEIN, J. B. LIAN, S. H. POCKWINSE, and S. MCNEIL (1999)
FASEB J 13, 157-166
 |  Abstract »  |  Full Text »  |  PDF »

Processing of Endogenous Pre-mRNAs in Association with SC-35 Domains Is Gene Specific.

K. P. Smith, P. T. Moen Jr., K. L. Wydner, J. R. Coleman, and J. B. Lawrence (1999)
J. Cell Biol. 144, 617-629
 |  Abstract »  |  Full Text »  |  PDF »

A Four-Dimensional View of Assembly of a Morphogenetic Protein during Sporulation in Bacillus subtilis.

K. D. Price and R. Losick (1999)
J. Bacteriol. 181, 781-790
 |  Abstract »  |  Full Text »

RNA Polymerase II Localizes at Sites of Human Cytomegalovirus Immediate-early RNA Synthesis and Processing.

S. P. Snaar, M. Vincent, and R. W. Dirks (1999)
J. Histochem. Cytochem. 47, 245-254
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The casein kinase Ialpha isoform is both physically positioned and functionally competent to regulate multiple events of mRNA metabolism.

S. Gross, J. Loijens, and R. Anderson (1999)
J. Cell Sci. 112, 2647-2656
 |  Abstract »  |  PDF »

Ultrastructural Analysis of Transcription and Splicing in the Cell Nucleus after Bromo-UTP Microinjection.

D. Cmarko, P. J. Verschure, T. E. Martin, M. E. Dahmus, S. Krause, X.-D. Fu, R. van Driel, and S. Fakan (1999)
Mol. Biol. Cell 10, 211-223
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Control of Human Immunodeficiency Virus Type 1 RNA Metabolism: Role of Splice Sites and Intron Sequences in Unspliced Viral RNA Subcellular Distribution.

B. Seguin, A. Staffa, and A. Cochrane (1998)
J. Virol. 72, 9503-9513
 |  Abstract »  |  Full Text »  |  PDF »

CD3/TCR Complex-Associated Lymphocyte Activation Gene-3 Molecules Inhibit CD3/TCR Signaling.

S. Hannier, M. Tournier, G. Bismuth, and F. Triebel (1998)
J. Immunol. 161, 4058-4065
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Core Histones and HIRIP3, a Novel Histone-Binding Protein, Directly Interact with WD Repeat Protein HIRA.

S. Lorain, J.-P. Quivy, F. Monier-Gavelle, C. Scamps, Y. Lécluse, G. Almouzni, and M. Lipinski (1998)
Mol. Cell. Biol. 18, 5546-5556
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Organization of Highly Acetylated Chromatin around Sites of Heterogeneous Nuclear RNA Accumulation.

M. J. Hendzel, M. J. Kruhlak, and D. P. Bazett-Jones (1998)
Mol. Biol. Cell 9, 2491-2507
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Nucleolar localization of early tRNA processing.

E. Bertrand, F. Houser-Scott, A. Kendall, R. H. Singer, and D. R. Engelke (1998)
Genes & Dev. 12, 2463-2468
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Endomitosis of Human Megakaryocytes Are Due to Abortive Mitosis.

N. Vitrat, K. Cohen-Solal, C. Pique, J. P. LeCouedic, F. Norol, A. K. Larsen, A. Katz, W. Vainchenker, and N. Debili (1998)
Blood 91, 3711-3723
 |  Abstract »  |  Full Text »  |  PDF »

NRP/B, a Novel Nuclear Matrix Protein, Associates With p110RB and Is Involved in Neuronal Differentiation.

T.-A. Kim, J. Lim, S. Ota, S. Raja, R. Rogers, B. Rivnay, H. Avraham, and S. Avraham (1998)
J. Cell Biol. 141, 553-566
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Structure and Function in the Nucleus.

A. I. Lamond and W. C. Earnshaw (1998)
Science 280, 547-553
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The RNP protein, RNPS1, associates with specific isoforms of the p34cdc2-related PITSLRE protein kinase in vivo.

P Loyer, J. Trembley, J. Lahti, and V. Kidd (1998)
J. Cell Sci. 111, 1495-1506
 |  Abstract »  |  PDF »

Molecular Characterization of a Novel, Widespread Nuclear Protein That Colocalizes with Spliceosome Components.

M. S. Schmidt-Zachmann, S. Knecht, and A. Krämer (1998)
Mol. Biol. Cell 9, 143-160
 |  Abstract »  |  Full Text »

Chromatin Condensation in Erythropoiesis Resolved by Multipixel Spectral Imaging: Differentiation Versus Apoptosis.

C. Rothmann, A. M. Cohen, and Z. Malik (1997)
J. Histochem. Cytochem. 45, 1097-1108
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a nuclear matrix targeting signal in the leukemia and bone-related AML/CBF-alpha transcription factors.

C. Zeng, A. J. van Wijnen, J. L. Stein, S. Meyers, W. Sun, L. Shopland, J. B. Lawrence, S. Penman, J. B. Lian, G. S. Stein, et al. (1997)
PNAS 94, 6746-6751
 |  Abstract »  |  Full Text »  |  PDF »

Targeting of U2AF65 to Sites of Active Splicing in the Nucleus.

M. Gama-Carvalho, R. D. Krauss, L. Chiang, J. Valcarcel, M. R. Green, and M. Carmo-Fonseca (1997)
J. Cell Biol. 137, 975-987
 |  Abstract »  |  Full Text »  |  PDF »

Structural Protein 4.1 in the Nucleus of Human Cells: Dynamic Rearrangements during Cell Division.

S. W. Krauss, C. A. Larabell, S. Lockett, P. Gascard, S. Penman, N. Mohandas, and J. A. Chasis (1997)
J. Cell Biol. 137, 275-289
 |  Abstract »  |  Full Text »  |  PDF »

Two proteins that cycle asynchronously between centrosomes and nuclear structures: Drosophila CP60 and CP190.

K Oegema, W. Marshall, J. Sedat, and B. Alberts (1997)
J. Cell Sci. 110, 1573-1583
 |  Abstract »  |  PDF »

Splicing factors associate with nuclear HCMV-IE transcripts after transcriptional activation of the gene, but dissociate upon transcription inhibition: evidence for a dynamic organization of splicing factors.

R. Dirks, E. de Pauw, and A. Raap (1997)
J. Cell Sci. 110, 515-522
 |  Abstract »  |  PDF »

A protein of the SR family of splicing factors binds extensively to exonic Balbiani ring pre-mRNA and accompanies the RNA from the gene to the nuclear pore..

A T Alzhanova-Ericsson, X Sun, N Visa, E Kiseleva, T Wurtz, and B Daneholt (1996)
Genes & Dev. 10, 2881-2893
 |  Abstract »  |  PDF »

DNA exposure and condensation in the X and 21 chromosomes.

T. Puck and R Johnson (1996)
Stem Cells 14, 548-557
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DNA hypomethylation can activate Xist expression and silence X-linked genes..

B Panning and R Jaenisch (1996)
Genes & Dev. 10, 1991-2002
 |  Abstract »  |  PDF »

Functional compartmentalization of the nucleus.

J Strouboulis and A. Wolffe (1996)
J. Cell Sci. 109, 1991-2000
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Active RNA polymerases are localized within discrete transcription ""factories' in human nuclei.

F. Iborra, A Pombo, D. Jackson, and P. Cook (1996)
J. Cell Sci. 109, 1427-1436
 |  Abstract »  |  PDF »

A U6 snRNA:pre-mRNA interaction can be rate-limiting for U1-independent splicing..

J D Crispino and P A Sharp (1995)
Genes & Dev. 9, 2314-2323
 |  Abstract »  |  PDF »

Increased Phosphorylation of Histone H1 in Mouse Fibroblasts Transformed with Oncogenes or Constitutively Active Mitogen-activated Protein Kinase Kinase.

D. N. Chadee, W. R. Taylor, R. A. R. Hurta, C. D. Allis, J. A. Wright, and J. R. Davie (1995)
J. Biol. Chem. 270, 20098-20105
 |  Abstract »  |  Full Text »  |  PDF »

Superresolution three-dimensional images of fluorescence in cells with minimal light exposure.

W. Carrington, R. Lynch, E. Moore, G Isenberg, K. Fogarty, and F. Fay (1995)
Science 268, 1483-1487
 |  Abstract »  |  PDF »

Overexpression of the arginine-rich carboxy-terminal region of U1 snRNP 70K inhibits both splicing and nucleocytoplasmic transport of mRNA..

J M Romac and J D Keene (1995)
Genes & Dev. 9, 1400-1410
 |  Abstract »  |  PDF »

The three-dimensional organization of ribosomal genes and the architecture of the nucleoli vary with G1, S and G2 phases.

H. Junera, C Masson, G Geraud, and D Hernandez-Verdun (1995)
J. Cell Sci. 108, 3427-3441
 |  Abstract »  |  PDF »

Localization of the glucocorticoid receptor in discrete clusters in the cell nucleus.

B van Steensel, M Brink, K van der Meulen, E. van Binnendijk, D. Wansink, L de Jong, E. de Kloet, and R van Driel (1995)
J. Cell Sci. 108, 3003-3011
 |  Abstract »  |  PDF »

'Chromosomal puffing' in diploid nuclei of Drosophila melanogaster.

S Gunawardena, E Heddle, and M. Rykowski (1995)
J. Cell Sci. 108, 1863-1872
 |  Abstract »  |  PDF »

Colocalization of a high molecular mass phosphoprotein of the nuclear matrix (p255) with spliceosomes.

S Bisotto, P Lauriault, M Duval, and M Vincent (1995)
J. Cell Sci. 108, 1873-1882
 |  Abstract »  |  PDF »

Nuclear distribution of Drosophila DNA topoisomerase II is sensitive to both RNase and DNase.

V. Meller and P. Fisher (1995)
J. Cell Sci. 108, 1651-1657
 |  Abstract »  |  PDF »

The organization of spliceosomal components in the nuclei of higher plants.

A. Beven, G. Simpson, J. Brown, and P. Shaw (1995)
J. Cell Sci. 108, 509-518
 |  Abstract »  |  PDF »

Three-dimensional co-location of RNA polymerase I and DNA during interphase and mitosis by confocal microscopy.

N Gilbert, L Lucas, C Klein, M Menager, N Bonnet, and D Ploton (1995)
J. Cell Sci. 108, 115-125
 |  Abstract »  |  PDF »

Does transcription by RNA polymerase play a direct role in the initiation of replication?.

A. Hassan and P. Cook (1994)
J. Cell Sci. 107, 1381-1387
 |  Abstract »  |  PDF »

Cytostellin distributes to nuclear regions enriched with splicing factors.

D. Bregman, L Du, Y Li, S Ribisi, and S. Warren (1994)
J. Cell Sci. 107, 387-396
 |  Abstract »  |  PDF »

Replication and transcription sites are colocalized in human cells.

A. Hassan, R. Errington, N. White, D. Jackson, and P. Cook (1994)
J. Cell Sci. 107, 425-434
 |  Abstract »  |  PDF »

Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA.

B. Sullenger and T. Cech (1993)
Science 262, 1566-1569
 |  Abstract »  |  PDF »

Higher level organization of individual gene transcription and RNA splicing.

Y Xing, C. Johnson, P. Dobner, and J. Lawrence (1993)
Science 259, 1326-1330
 |  Abstract »  |  PDF »

Cytoarchitecture of size-excluding compartments in living cells.

D. Provance, A McDowall, M Marko, and K Luby-Phelps (1993)
J. Cell Sci. 106, 565-577
 |  Abstract »  |  PDF »

In vivo observation of the puff-specific protein no-on transient A (NONA) in nuclei of Drosophila embryos.

P Buchenau, D. Arndt-Jovin, and H Saumweber (1993)
J. Cell Sci. 106, 189-199
 |  Abstract »  |  PDF »

Role of Chromosome Territories in the Functional Compartmentalization of the Cell Nucleus.

T. Cremer, A. Kurz, R. Zirbel, S. Dietzel, B. Rinke, E. Schrock, M.R. Speicher, U. Mathieu, A. Jauch, P. Emmerich, et al. (1993)
Cold Spring Harb Symp Quant Biol 58, 777-792
 |  Abstract »  |  PDF »

Dynamics of Transcription and Pre-mRNA Splicing within the Mammalian Cell Nucleus.

D.L. Spector, R.T. O'Keefe, and L.F. Jimenez-Garcia (1993)
Cold Spring Harb Symp Quant Biol 58, 799-805
 |  Abstract »  |  PDF »

Probing Functional Organization within the Nucleus: Is Genome Structure Integrated with RNA Metabolism?.

J.B. Lawrence, K.C. Carter, and X. Xing (1993)
Cold Spring Harb Symp Quant Biol 58, 807-818
 |  Abstract »  |  PDF »

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