Science 12 February 1993: Vol. 259. no. 5097, pp. 990 - 993 DOI: 10.1126/science.7679801

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Articles

CD154-CD40 Interactions Are Essential for Thymus-Dependent Antibody Production in Zebrafish: Insights into the Origin of Costimulatory Pathway in Helper T Cell-Regulated Adaptive Immunity in Early Vertebrates.

Y.-F. Gong, L.-X. Xiang, and J.-Z. Shao (2009)
J. Immunol. 182, 7749-7762
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting.

N. S. Longo, P. L. Lugar, S. Yavuz, W. Zhang, P. H. L. Krijger, D. E. Russ, D. D. Jima, S. S. Dave, A. C. Grammer, and P. E. Lipsky (2009)
Blood 113, 3706-3715
 |  Abstract »  |  Full Text »  |  PDF »

Loss of IL-7 Receptor {alpha} on CD4+ T Cells Defines Terminally Differentiated B Cell-Helping Effector T Cells in a B Cell-Rich Lymphoid Tissue.

H. W. Lim and C. H. Kim (2007)
J. Immunol. 179, 7448-7456
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A primary immunodeficiency characterized by defective immunoglobulin class switch recombination and impaired DNA repair.

S. Peron, Q. Pan-Hammarstrom, K. Imai, L. Du, N. Taubenheim, O. Sanal, L. Marodi, A. Bergelin-Besancon, M. Benkerrou, J.-P. de Villartay, et al. (2007)
J. Exp. Med. 204, 1207-1216
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The structural basis of hyper IgM deficiency - CD40L mutations.

J. Thusberg and M. Vihinen (2007)
Protein Eng. Des. Sel. 20, 133-141
 |  Abstract »  |  Full Text »  |  PDF »

Prospect of Targeting the CD40 Pathway for Cancer Therapy.

R. H. Vonderheide (2007)
Clin. Cancer Res. 13, 1083-1088
 |  Abstract »  |  Full Text »  |  PDF »

X-linked Hyper-IgM Syndrome Associated With a Rapid Course of Multifocal Leukoencephalopathy.

Z. Aschermann, E. Gomori, G. G. Kovacs, E. Pal, G. Simon, S. Komoly, L. Marodi, and Z. Illes (2007)
Arch Neurol 64, 273-276
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c-Rel plays a key role in deficient activation of B cells from a non-X-linked hyper-IgM patient.

K. T. Lu, F. L. Sinquett, R. L. Dryer, C. Song, and L. R. Covey (2006)
Blood 108, 3769-3776
 |  Abstract »  |  Full Text »  |  PDF »

Development of Autoimmunity in IL-14{alpha}-Transgenic Mice.

L. Shen, C. Zhang, T. Wang, S. Brooks, R. J. Ford, Y. C. Lin-Lee, A. Kasianowicz, V. Kumar, L. Martin, P. Liang, et al. (2006)
J. Immunol. 177, 5676-5686
 |  Abstract »  |  Full Text »  |  PDF »

An antibody-deficiency syndrome due to mutations in the CD19 gene..

M. C. van Zelm, I. Reisli, M. van der Burg, D. Castano, C. J.M. van Noesel, M. J.D. van Tol, C. Woellner, B. Grimbacher, P. J. Patino, J. J.M. van Dongen, et al. (2006)
N. Engl. J. Med. 354, 1901-1912
 |  Abstract »  |  Full Text »  |  PDF »

Epstein-Barr Virus Can Establish Infection in the Absence of a Classical Memory B-Cell Population.

M. Conacher, R. Callard, K. McAulay, H. Chapel, D. Webster, D. Kumararatne, A. Chandra, G. Spickett, P. A. Hopwood, and D. H. Crawford (2005)
J. Virol. 79, 11128-11134
 |  Abstract »  |  Full Text »  |  PDF »

Maintenance of the CD40-related immunodeficient response in hyper-IgM B cells immortalized with a LMP1-regulated mini-EBV.

K. T. Lu, R. L. Dryer, C. Song, and L. R. Covey (2005)
J. Leukoc. Biol. 78, 620-629
 |  Abstract »  |  Full Text »  |  PDF »

CD40 Ligand: Not Bad to the Bone (Marrow), After All.

O. A. Ajijola, P. J. Goldschmidt-Clermont, and L. L. Satterwhite (2005)
Arterioscler Thromb Vasc Biol 25, 1088-1090
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Atherogenesis in Mice Does Not Require CD40 Ligand From Bone Marrow-Derived Cells.

U. Bavendiek, A. Zirlik, S. LaClair, L. MacFarlane, P. Libby, and U. Schonbeck (2005)
Arterioscler Thromb Vasc Biol 25, 1244-1249
 |  Abstract »  |  Full Text »  |  PDF »

Two waves of memory B-cell generation in the primary immune response.

A. Inamine, Y. Takahashi, N. Baba, K. Miyake, T. Tokuhisa, T. Takemori, and R. Abe (2005)
Int. Immunol. 17, 581-589
 |  Abstract »  |  Full Text »  |  PDF »

Molecular analysis of a large cohort of patients with the hyper immunoglobulin M (IgM) syndrome.

W.-I Lee, T. R. Torgerson, M. J. Schumacher, L. Yel, Q. Zhu, and H. D. Ochs (2005)
Blood 105, 1881-1890
 |  Abstract »  |  Full Text »  |  PDF »

Deficiency of somatic hypermutation of the antibody light chain is associated with increased frequency of severe respiratory tract infection in common variable immunodeficiency.

P. Andersen, H. Permin, V. Andersen, L. Schejbel, P. Garred, A. Svejgaard, and T. Barington (2005)
Blood 105, 511-517
 |  Abstract »  |  Full Text »  |  PDF »

Tracking CD40 signaling during germinal center development.

K. Basso, U. Klein, H. Niu, G. A. Stolovitzky, Y. Tu, A. Califano, G. Cattoretti, and R. Dalla-Favera (2004)
Blood 104, 4088-4096
 |  Abstract »  |  Full Text »  |  PDF »

Biased Immunoglobulin G (IgG) Subclass Production in a Case of Hyper-IgM Syndrome.

G. R. McLean, K. K. Miller, J. W. Schrader, and A. K. Junker (2004)
Clin. Vaccine Immunol. 11, 1192-1193
 |  Abstract »  |  Full Text »  |  PDF »

Clonotypic IgM V/D/J sequence analysis in Waldenstrom macroglobulinemia suggests an unusual B-cell origin and an expansion of polyclonal B cells in peripheral blood.

J. Kriangkum, B. J. Taylor, S. P. Treon, M. J. Mant, A. R. Belch, and L. M. Pilarski (2004)
Blood 104, 2134-2142
 |  Abstract »  |  Full Text »  |  PDF »

The role of CD40 ligand in systemic lupus erythematosus.

J Yazdany and J Davis (2004)
Lupus 13, 377-380
 |  Abstract »  |  PDF »

NF-{kappa}B and Oct-2 Synergize to Activate the Human 3' Igh hs4 Enhancer in B Cells.

M. A. Sepulveda, A. V. Emelyanov, and B. K. Birshtein (2004)
J. Immunol. 172, 1054-1064
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Interaction between Protein Kinase D and TNF Receptor-Associated Factor Molecules Regulates B Cell Receptor-CD40 Synergy.

S. A. Haxhinasto and G. A. Bishop (2003)
J. Immunol. 171, 4655-4662
 |  Abstract »  |  Full Text »  |  PDF »

S{epsilon}S{micro} and S{epsilon}S{gamma} Switch Circles in Human Nasal Mucosa Following Ex Vivo Allergen Challenge: Evidence for Direct as Well as Sequential Class Switch Recombination.

L. Cameron, A. S. Gounni, S. Frenkiel, F. Lavigne, D. Vercelli, and Q. Hamid (2003)
J. Immunol. 171, 3816-3822
 |  Abstract »  |  Full Text »  |  PDF »

Emerging Applications of the Tumor Necrosis Factor Family of Ligands and Receptors in Cancer Therapy.

A. Younes and M. E. Kadin (2003)
J. Clin. Oncol. 21, 3526-3534
 |  Abstract »  |  Full Text »  |  PDF »

Combined Autoimmune Models of Arthritis Reveal Shared and Independent Qualitative (Binary) and Quantitative Trait Loci.

V. A. Adarichev, J. C. Valdez, T. Bardos, A. Finnegan, K. Mikecz, and T. T. Glant (2003)
J. Immunol. 170, 2283-2292
 |  Abstract »  |  Full Text »  |  PDF »

Splenic Marginal Zone Lymphoma with Villous Lymphocytes Shows On-Going Immunoglobulin Gene Mutations.

A. Tierens, J. Delabie, A. Malecka, J. Wang, A. Gruszka-Westwood, D. Catovsky, and E. Matutes (2003)
Am. J. Pathol. 162, 681-689
 |  Abstract »  |  Full Text »  |  PDF »

A Complex Containing Polypyrimidine Tract-Binding Protein Is Involved in Regulating the Stability of CD40 Ligand (CD154) mRNA.

P. A. Kosinski, J. Laughlin, K. Singh, and L. R. Covey (2003)
J. Immunol. 170, 979-988
 |  Abstract »  |  Full Text »  |  PDF »

Immunodeficiency Disorders.

M. D. Cooper, L. L. Lanier, M. E. Conley, and J. M. Puck (2003)
Hematology 2003, 314-330
 |  Abstract »  |  Full Text »  |  PDF »

The CD154/CD40 Interaction Required for Retrovirus-Induced Murine Immunodeficiency Syndrome Is Not Mediated by Upregulation of the CD80/CD86 Costimulatory Molecules.

K. A. Green, W. J. Cook, A. H. Sharpe, and W. R. Green (2002)
J. Virol. 76, 13106-13110
 |  Abstract »  |  Full Text »  |  PDF »

Mucosal Plasma Cell Repertoire During HIV-1 Infection.

R. W. Scamurra, D. B. Nelson, X. M. Lin, D. J. Miller, G. J. Silverman, T. Kappel, J. R. Thurn, E. Lorenz, A. Kulkarni-Narla, and E. N. Janoff (2002)
J. Immunol. 169, 4008-4016
 |  Abstract »  |  Full Text »  |  PDF »

Clustering of CD40 Ligand Is Required to Form a Functional Contact with CD40.

H. Grassme, J. Bock, J. Kun, and E. Gulbins (2002)
J. Biol. Chem. 277, 30289-30299
 |  Abstract »  |  Full Text »  |  PDF »

Autoimmunity in human primary immunodeficiency diseases.

P. D. Arkwright, M. Abinun, and A. J. Cant (2002)
Blood 99, 2694-2702
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Dissection of B cell differentiation during primary immune responses in mice with altered CD40 signals.

T. Yasui, M. Muraoka, Y. Takaoka-Shichijo, I. Ishida, N. Takegahara, J. Uchida, A. Kumanogoh, S. Suematsu, M. Suzuki, and H. Kikutani (2002)
Int. Immunol. 14, 319-329
 |  Abstract »  |  Full Text »  |  PDF »

CD40 Signaling in B Cells Regulates the Expression of the Pim-1 Kinase Via the NF-{kappa}B Pathway.

N. Zhu, L. M. Ramirez, R. L. Lee, N. S. Magnuson, G. A. Bishop, and M. R. Gold (2002)
J. Immunol. 168, 744-754
 |  Abstract »  |  Full Text »  |  PDF »

Abnormal CD40 Ligand (CD154) Expression in Human Immunodeficiency Virus-Infected Children.

M. R. G. O'Gorman, B. DuChateau, M. Paniagua, J. Hunt, N. Bensen, and R. Yogev (2001)
Clin. Vaccine Immunol. 8, 1104-1109
 |  Abstract »  |  Full Text »  |  PDF »

Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM.

S. Ferrari, S. Giliani, A. Insalaco, A. Al-Ghonaium, A. R. Soresina, M. Loubser, M. A. Avanzini, M. Marconi, R. Badolato, A. G. Ugazio, et al. (2001)
PNAS 98, 12614-12619
 |  Abstract »  |  Full Text »  |  PDF »

Phase I Study of Recombinant Human CD40 Ligand in Cancer Patients.

R. H. Vonderheide, J. P. Dutcher, J. E. Anderson, S. G. Eckhardt, K. F. Stephans, B. Razvillas, S. Garl, M. D. Butine, V. P. Perry, R. J. Armitage, et al. (2001)
J. Clin. Oncol. 19, 3280-3287
 |  Abstract »  |  Full Text »  |  PDF »

Vaccination against the Intracellular Pathogens Leishmania major and L. amazonensis by Directing CD40 Ligand to Macrophages.

G. Chen, P. A. Darrah, and D. M. Mosser (2001)
Infect. Immun. 69, 3255-3263
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of the CD154-Positive and CD40-Positive Cellular Subsets Required for Pathogenesis in Retrovirus-Induced Murine Immunodeficiency.

K. A. Green, R. J. Noelle, B. G. Durell, and W. R. Green (2001)
J. Virol. 75, 3581-3589
 |  Abstract »  |  Full Text »

Regulation of CD40 function by its isoforms generated through alternative splicing.

M. Tone, Y. Tone, P. J. Fairchild, M. Wykes, and H. Waldmann (2001)
PNAS 98, 1751-1756
 |  Abstract »  |  Full Text »  |  PDF »

Increased T Cell Autoreactivity in the Absence of CD40-CD40 Ligand Interactions: A Role of CD40 in Regulatory T Cell Development.

A. Kumanogoh, X. Wang, I. Lee, C. Watanabe, M. Kamanaka, W. Shi, K. Yoshida, T. Sato, S. Habu, M. Itoh, et al. (2001)
J. Immunol. 166, 353-360
 |  Abstract »  |  Full Text »  |  PDF »

Immunodeficiency, Immunosuppression, and Susceptibility to Neoplasms.

R. S. Schwartz (2000)
J Natl Cancer Inst Monographs 2000, 5-9
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Primary Immunodeficiency Diseases Due to Defects in Lymphocytes.

R. H. Buckley (2000)
N. Engl. J. Med. 343, 1313-1324
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Human Double-Negative T Cells in Systemic Lupus Erythematosus Provide Help for IgG and Are Restricted by CD1c.

P. A. Sieling, S. A. Porcelli, B. T. Duong, F. Spada, B. R. Bloom, B. Diamond, and B. H. Hahn (2000)
J. Immunol. 165, 5338-5344
 |  Abstract »  |  Full Text »  |  PDF »

Soluble CD40 ligand induces selective proliferation of lymphoma cells in primary mantle cell lymphoma cell cultures.

N. S. Andersen, J. K. Larsen, J. Christiansen, L. B. Pedersen, N. S. Christophersen, C. H. Geisler, and J. Jurlander (2000)
Blood 96, 2219-2225
 |  Abstract »  |  Full Text »  |  PDF »

A Role for CD40-CD40 Ligand Interactions in the Generation of Type 1 Cytokine Responses in Human Leprosy.

P. S. Yamauchi, J. R. Bleharski, K. Uyemura, J. Kim, P. A. Sieling, A. Miller, H. Brightbill, K. Schlienger, T. H. Rea, and R. L. Modlin (2000)
J. Immunol. 165, 1506-1512
 |  Abstract »  |  Full Text »  |  PDF »

CD40-ligand stimulates myelopoiesis by regulating flt3-ligand and thrombopoietin production in bone marrow stromal cells.

A. Solanilla, J. Dechanet, A. El Andaloussi, M. Dupouy, F. Godard, J. Chabrol, P. Charbord, J. Reiffers, A. T. Nurden, B. Weksler, et al. (2000)
Blood 95, 3758-3764
 |  Abstract »  |  Full Text »  |  PDF »

CD40 Ligand (CD154) Enhances the Th1 and Antibody Responses to Respiratory Syncytial Virus in the BALB/c Mouse.

R. A. Tripp, L. Jones, L. J. Anderson, and M. P. Brown (2000)
J. Immunol. 164, 5913-5921
 |  Abstract »  |  Full Text »  |  PDF »

CD134L Engagement Enhances Human B Cell Ig Production: CD154/CD40, CD70/CD27, and CD134/CD134L Interactions Coordinately Regulate T Cell-Dependent B Cell Responses.

S. Morimoto, Y. Kanno, Y. Tanaka, Y. Tokano, H. Hashimoto, S. Jacquot, C. Morimoto, S. F. Schlossman, H. Yagita, K. Okumura, et al. (2000)
J. Immunol. 164, 4097-4104
 |  Abstract »  |  Full Text »  |  PDF »

A Transcriptional Defect Underlies B Lymphocyte Dysfunction in a Patient Diagnosed with Non-X-Linked Hyper-IgM Syndrome.

A. Bhushan, B. Barnhart, S. Shone, C. Song, and L. R. Covey (2000)
J. Immunol. 164, 2871-2880
 |  Abstract »  |  Full Text »  |  PDF »

Blockade of CD28-B7, But Not CD40-CD154, Prevents Costimulation of Allogeneic Porcine and Xenogeneic Human Anti-Porcine T Cell Responses.

R. S. Lee, K. Yamada, K. L. Womer, E. P. Pillsbury, K. S. Allison, A. E. Marolewski, D. Geng, A. D. Thall, J. S. Arn, D. H. Sachs, et al. (2000)
J. Immunol. 164, 3434-3444
 |  Abstract »  |  Full Text »  |  PDF »

Human Interdigitating Dendritic Cells Induce Isotype Switching and IL-13-Dependent IgM Production in CD40-Activated Naive B Cells.

B. Johansson, S. Ingvarsson, P. Bjorck, and C. A. K. Borrebaeck (2000)
J. Immunol. 164, 1847-1854
 |  Abstract »  |  Full Text »  |  PDF »

Correction of the Hyper-IgM Syndrome after Liver and Bone Marrow Transplantation.

N. Hadzic, A. Pagliuca, M. Rela, B. Portmann, A. Jones, P. Veys, N. D. Heaton, G. J. Mufti, and G. Mieli-Vergani (2000)
N. Engl. J. Med. 342, 320-324
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APRIL/TRDL-1, a Tumor Necrosis Factor-like Ligand, Stimulates Cell Death.

K. Kelly, E. Manos, G. Jensen, L. Nadauld, and D. A. Jones (2000)
Cancer Res. 60, 1021-1027
 |  Abstract »  |  Full Text »

Th2-Dependent B Cell Responses in the Absence of CD40-CD40 Ligand Interactions.

N. Chirmule, J. Tazelaar, and J. M. Wilson (2000)
J. Immunol. 164, 248-255
 |  Abstract »  |  Full Text »  |  PDF »

CD154 Variants Associated with Hyper-IgM Syndrome Can Form Oligomers and Trigger CD40-mediated Signals.

E. Garber, L. Su, B. Ehrenfels, M. Karpusas, and Y.-M. Hsu (1999)
J. Biol. Chem. 274, 33545-33550
 |  Abstract »  |  Full Text »  |  PDF »

Hyperexpression of CD40 Ligand (CD154) in Inflammatory Bowel Disease and Its Contribution to Pathogenic Cytokine Production.

Z. Liu, S. Colpaert, G. R. D'Haens, A. Kasran, M. d. Boer, P. Rutgeerts, K. Geboes, and J. L. Ceuppens (1999)
J. Immunol. 163, 4049-4057
 |  Abstract »  |  Full Text »  |  PDF »

Human Endothelial Cells Augment Early CD40 Ligand Expression in Activated CD4+ T Cells Through LFA-3-Mediated Stabilization of mRNA.

K. Murakami, W. Ma, R. Fuleihan, and J. S. Pober (1999)
J. Immunol. 163, 2667-2673
 |  Abstract »  |  Full Text »  |  PDF »

Deficient Cellular Immunity--Finding and Fixing the Defects.

P. D. Greenberg and S. R. Riddell (1999)
Science 285, 546-551
 |  Abstract »  |  Full Text »

Activation of the Janus Kinase 3-STAT5a Pathway After CD40 Triggering of Human Monocytes But Not of Resting B Cells.

P. Revy, C. Hivroz, G. Andreu, P. Graber, C. Martinache, A. Fischer, and A. Durandy (1999)
J. Immunol. 163, 787-793
 |  Abstract »  |  Full Text »  |  PDF »

Co-ligation of CD44 on naive human tonsillar B cells induces progression towards a germinal center phenotype.

S. Ingvarsson, K. Dahlenborg, R. Carlsson, and C. A. K. Borrebaeck (1999)
Int. Immunol. 11, 739-744
 |  Abstract »  |  Full Text »  |  PDF »

Defective Self-Reactive Antibody Repertoire of Serum IgM in Patients with Hyper-IgM Syndrome.

S. Lacroix-Desmazes, I. Resnick, D. Stahl, L. Mouthon, T. Espanol, J. Levy, S. V. Kaveri, L. Notarangelo, M. Eibl, A. Fischer, et al. (1999)
J. Immunol. 162, 5601-5608
 |  Abstract »  |  Full Text »  |  PDF »

CD40 Ligand Mutants Responsible for X-linked Hyper-IgM Syndrome Associate with Wild Type CD40 Ligand.

K. Seyama, W. R. A. Osborne, and H. D. Ochs (1999)
J. Biol. Chem. 274, 11310-11320
 |  Abstract »  |  Full Text »  |  PDF »

An 11-Amino Acid Sequence in the Cytoplasmic Domain of CD40 Is Sufficient for Activation of c-Jun N-Terminal Kinase, Activation of MAPKAP Kinase-2, Phosphorylation of I{kappa}B{alpha}, and Protection of WEHI-231 Cells from Anti-IgM-Induced Growth Arrest.

C. L. Sutherland, D. L. Krebs, and M. R. Gold (1999)
J. Immunol. 162, 4720-4730
 |  Abstract »  |  Full Text »  |  PDF »

TWEAK Induces Angiogenesis and Proliferation of Endothelial Cells.

C. N. Lynch, Y. C. Wang, J. K. Lund, Y.-W. Chen, J. A. Leal, and S. R. Wiley (1999)
J. Biol. Chem. 274, 8455-8459
 |  Abstract »  |  Full Text »  |  PDF »

Differential Responses to CD40 Ligation Among Burkitt Lymphoma Lines That Are Uniformly Responsive to Epstein-Barr Virus Latent Membrane Protein 1.

N. V. Henriquez, E. Floettmann, M. Salmon, M. Rowe, and A. B. Rickinson (1999)
J. Immunol. 162, 3298-3307
 |  Abstract »  |  Full Text »  |  PDF »

Responsiveness of peripheral blood B cells to recombinant CD40 ligand in patients with systemic lupus erythematosus.

M Harigai, M Hara, C Fukasawa, S Nakazawa, Y Kawaguchi, N Kamatani, and S Kashiwazaki (1999)
Lupus 8, 227-233
 |  Abstract »  |  PDF »

Requirement for Nuclear Factor-{kappa}B Activation by a Distinct Subset of CD40-Mediated Effector Functions in B Lymphocytes.

Y. Hsing and G. A. Bishop (1999)
J. Immunol. 162, 2804-2811
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of Disease and Injury: Utilization of Mutants, Monoclonals, and Molecular Methods.

J. C.L. Schuh and K. A. Harrington (1999)
Toxicol Pathol 27, 115-120
 |  Abstract »  |  PDF »

The Role of CD8+ CD40L+ T Cells in the Formation of Germinal Centers in Rheumatoid Synovitis.

U. G. Wagner, P. J. Kurtin, A. Wahner, M. Brackertz, D. J. Berry, J. J. Goronzy, and C. M. Weyand (1998)
J. Immunol. 161, 6390-6397
 |  Abstract »  |  Full Text »  |  PDF »

Mutations of the CD40 Ligand Gene and Its Effect on CD40 Ligand Expression in Patients With X-Linked Hyper IgM Syndrome.

K. Seyama, S. Nonoyama, I. Gangsaas, D. Hollenbaugh, H. F. Pabst, A. Aruffo, and H. D. Ochs (1998)
Blood 92, 2421-2434
 |  Abstract »  |  Full Text »  |  PDF »

Requirement for Dual Signals by Anti-CD40 and IL-4 for the Induction of Nuclear Factor-{kappa}B, IL-6, and IgE in Human B Lymphocytes.

J. D. Jeppson, H. R. Patel, N. Sakata, J. Domenico, N. Terada, and E. W. Gelfand (1998)
J. Immunol. 161, 1738-1742
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Mechanisms of Promoter Regulation of the gp34 Gene That Is Trans-activated by an Oncoprotein Tax of Human T Cell Leukemia Virus Type I.

K. Ohtani, A. Tsujimoto, T. Tsukahara, N. Numata, S. Miura, K. Sugamura, and M. Nakamura (1998)
J. Biol. Chem. 273, 14119-14129
 |  Abstract »  |  Full Text »  |  PDF »

Dominant Signals Leading to Inhibitor {kappa}B Protein Degradation Mediate CD40 Ligand Rescue of WEHI 231 Immature B Cells from Receptor-Mediated Apoptosis.

S. L. Schauer, R. E. Bellas, and G. E. Sonenshein (1998)
J. Immunol. 160, 4398-4405
 |  Abstract »  |  Full Text »  |  PDF »

Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) Stimulates Extracellular Signal-regulated Kinase (ERK) Activity in CD40 Signaling Along a Ras-independent Pathway.

M. Kashiwada, Y. Shirakata, J.-I. Inoue, H. Nakano, K. Okazaki, K. Okumura, T. Yamamoto, H. Nagaoka, and T. Takemori (1998)
J. Exp. Med. 187, 237-244
 |  Abstract »  |  Full Text »  |  PDF »

CD40 Ligand Exerts Differential Effects on the Expression of I{gamma} Transcripts in Subclones of an IgM+ Human B Cell Lymphoma Line.

G. S. Ford, C. H. Yin, B. Barnhart, K. Sztam, and L. R. Covey (1998)
J. Immunol. 160, 595-605
 |  Abstract »  |  Full Text »  |  PDF »

Soluble and Membrane-bound Forms of Signaling Lymphocytic Activation Molecule (SLAM) Induce Proliferation and Ig Synthesis by Activated Human B Lymphocytes.

J. Punnonen, B. G. Cocks, J. M. Carballido, B. Bennett, D. Peterson, G. Aversa, and J. E. d. Vries (1997)
J. Exp. Med. 185, 993-1004
 |  Abstract »  |  Full Text »  |  PDF »

CD40 Ligation on Human Cord Blood CD34+Hematopoietic Progenitors Induces Their Proliferation and Differentiation into Functional Dendritic Cells.

L. Flores-Romo, P. Bjorck, V. Duvert, C. van Kooten, S. Saeland, and J. Banchereau (1997)
J. Exp. Med. 185, 341-350
 |  Abstract »  |  Full Text »  |  PDF »

Heteromultimeric Complexes of CD40 Ligand Are Present on the Cell Surface of Human T Lymphocytes.

Y.-M. Hsu, J. Lucci, L. Su, B. Ehrenfels, E. Garber, and D. Thomas (1997)
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The Tumor Necrosis Factor Ligand and Receptor Families.

F. Bazzoni and B. Beutler (1996)
N. Engl. J. Med. 334, 1717-1725
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Correction of X-Linked Hyper-IgM Syndrome by Allogeneic Bone Marrow Transplantation.

C. Thomas, G. de Saint Basile, F. Le Deist, D. Theophile, M. Benkerrou, E. Haddad, S. Blanche, and A. Fischer (1995)
N. Engl. J. Med. 333, 426-429
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The Primary Immunodeficiencies.

F. S. Rosen, M. D. Cooper, and R. J.P. Wedgwood (1995)
N. Engl. J. Med. 333, 431-440
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Activation of the B-cell Surface Receptor CD40 Induces A20, a Novel Zinc Finger Protein That Inhibits Apoptosis.

V. Sarma, Z. Lin, L. Clark, B. M. Rust, M. Tewari, R. J. Noelle, and V. M. Dixit (1995)
J. Biol. Chem. 270, 12343-12346
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Involvement of CRAF1, a relative of TRAF, in CD40 signaling.

G Cheng, A. Cleary, Z. Ye, D. Hong, S Lederman, and D Baltimore (1995)
Science 267, 1494-1498
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Unraveling function in the TNF ligand and receptor families.

B Beutler and C van Huffel (1994)
Science 264, 667-668
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A lymphotoxin-beta-specific receptor.

P. Crowe, T. VanArsdale, B. Walter, C. Ware, C Hession, B Ehrenfels, J. Browning, W. Din, R. Goodwin, and C. Smith (1994)
Science 264, 707-710
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Prenatal Diagnosis of X-Linked Hyper-IgM Syndrome.

J. P. DiSanto, S. Markiewicz, J.-F. Gauchat, J.-Y. Bonnefoy, A. Fischer, and G. de Saint Basile (1994)
N. Engl. J. Med. 330, 969-973
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The Genetic Basis of Immunoglobulin-Class Switching.

R. S. Geha and F. S. Rosen (1994)
N. Engl. J. Med. 330, 1008-1009
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X-linked Lymphoproliferative Disease: Detection of a Paternally Inherited Mutation in a German Family Using Haplotype Analysis.

V. Schuster, W. Kress, W. Friedrich, T. Grimm, and H. W. Kreth (1993)
Arch Pediatr Adolesc Med 147, 1303-1305
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A genetic linkage map of the mouse: current applications and future prospects.

N. Copeland, N. Jenkins, D. Gilbert, J. Eppig, L. Maltais, J. Miller, W. Dietrich, A Weaver, S. Lincoln, R. Steen, et al. (1993)
Science 262, 57-66
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Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40.

F. Durie, R. Fava, T. Foy, A Aruffo, J. Ledbetter, and R. Noelle (1993)
Science 261, 1328-1330
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