Science 15 January 1993: Vol. 259. no. 5093, pp. 370 - 373 DOI: 10.1126/science.8420005

Prev | Table of Contents | Next

Articles

Abscisic Acid Is an Endogenous Stimulator of Insulin Release from Human Pancreatic Islets with Cyclic ADP Ribose as Second Messenger.

S. Bruzzone, N. Bodrato, C. Usai, L. Guida, I. Moreschi, R. Nano, B. Antonioli, F. Fruscione, M. Magnone, S. Scarfi, et al. (2008)
J. Biol. Chem. 283, 32188-32197
 |  Abstract »  |  Full Text »  |  PDF »

Evolution and Function of the ADP Ribosyl Cyclase/CD38 Gene Family in Physiology and Pathology.

F. Malavasi, S. Deaglio, A. Funaro, E. Ferrero, A. L. Horenstein, E. Ortolan, T. Vaisitti, and S. Aydin (2008)
Physiol Rev 88, 841-886
 |  Abstract »  |  Full Text »  |  PDF »

Localization of the Cyclic ADP-Ribose-Dependent Calcium Signaling Pathway in Bovine Rod Outer Segments.

I. Panfoli, S. Ravera, A. Fabiano, R. Magrassi, A. Diaspro, A. Morelli, and I. M. Pepe (2007)
Invest. Ophthalmol. Vis. Sci. 48, 978-984
 |  Abstract »  |  Full Text »  |  PDF »

From The Cover: ADP-ribosyl cyclases generate two unusual adenine homodinucleotides with cytotoxic activity on mammalian cells.

G. Basile, O. Taglialatela-Scafati, G. Damonte, A. Armirotti, S. Bruzzone, L. Guida, L. Franco, C. Usai, E. Fattorusso, A. De Flora, et al. (2005)
PNAS 102, 14509-14514
 |  Abstract »  |  Full Text »  |  PDF »

PKA-Dependent and PKA-Independent Pathways for cAMP-Regulated Exocytosis.

S. Seino and T. Shibasaki (2005)
Physiol Rev 85, 1303-1342
 |  Abstract »  |  Full Text »  |  PDF »

CD38/cyclic ADP-ribose signaling: role in the regulation of calcium homeostasis in airway smooth muscle.

D. A. Deshpande, T. A. White, S. Dogan, T. F. Walseth, R. A. Panettieri, and M. S. Kannan (2005)
Am J Physiol Lung Cell Mol Physiol 288, L773-L788
 |  Abstract »  |  Full Text »  |  PDF »

Abscisic Acid Signaling through Cyclic ADP-ribose in Hydroid Regeneration.

S. Puce, G. Basile, G. Bavestrello, S. Bruzzone, C. Cerrano, M. Giovine, A. Arillo, and E. Zocchi (2004)
J. Biol. Chem. 279, 39783-39788
 |  Abstract »  |  Full Text »  |  PDF »

Cyclic ADP-ribose, a putative Ca2+-mobilizing second messenger, operates in submucosal gland acinar cells.

K. Sasamori, T. Sasaki, S. Takasawa, T. Tamada, M. Nara, T. Irokawa, S. Shimura, K. Shirato, and T. Hattori (2004)
Am J Physiol Lung Cell Mol Physiol 287, L69-L78
 |  Abstract »  |  Full Text »  |  PDF »

Changes in CD38 Expression and ADP-Ribosyl Cyclase Activity in Rat Myometrium During Pregnancy: Influence of Sex Steroid Hormones.

S. Dogan, D. A. Deshpande, M. S. Kannan, and T. F. Walseth (2004)
Biol Reprod 71, 97-103
 |  Abstract »  |  Full Text »  |  PDF »

Tacrolimus Impairment of Insulin Secretion in Isolated Rat Islets Occurs at Multiple Distal Sites in Stimulus-Secretion Coupling.

Y. Uchizono, M. Iwase, U. Nakamura, N. Sasaki, D. Goto, and M. Iida (2004)
Endocrinology 145, 2264-2272
 |  Abstract »  |  Full Text »  |  PDF »

FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells.

Y.-X. Wang, Y.-M. Zheng, Q.-B. Mei, Q.-S. Wang, M. L. Collier, S. Fleischer, H.-B. Xin, and M. I. Kotlikoff (2004)
Am J Physiol Cell Physiol 286, C538-C546
 |  Abstract »  |  Full Text »

NAD+ Ameliorates Inflammation-Induced Epithelial Barrier Dysfunction in Cultured Enterocytes and Mouse Ileal Mucosa.

X. Han, T. Uchiyama, P. L. Sappington, A. Yaguchi, R. Yang, M. P. Fink, and R. L. Delude (2003)
J. Pharmacol. Exp. Ther. 307, 443-449
 |  Abstract »  |  Full Text »  |  PDF »

Hormonal Control of ADP-ribosyl Cyclase Activity in Pancreatic Acinar Cells from Rats.

L. Sternfeld, E. Krause, A. H. Guse, and I. Schulz (2003)
J. Biol. Chem. 278, 33629-33636
 |  Abstract »  |  Full Text »  |  PDF »

Ryanodine Receptor Type I and Nicotinic Acid Adenine Dinucleotide Phosphate Receptors Mediate Ca2+ Release from Insulin-containing Vesicles in Living Pancreatic beta -Cells (MIN6).

K. J. Mitchell, F. A. Lai, and G. A. Rutter (2003)
J. Biol. Chem. 278, 11057-11064
 |  Abstract »  |  Full Text »  |  PDF »

Disordered osteoclast formation and function in a CD38 (ADP-ribosyl cyclase)-deficient mouse establishes an essential role for CD38 in bone resorption.

L. SUN, J. IQBAL, S. DOLGILEVICH, T. YUEN, X.-B. WU, B. S. MOONGA, O. A. ADEBANJO, P. J. R. BEVIS, F. LUND, C. L.-H. HUANG, et al. (2003)
FASEB J 17, 369-375
 |  Abstract »  |  Full Text »  |  PDF »

ABA- and cADPR-mediated effects on respiration and filtration downstream of the temperature-signaling cascade in sponges.

E. Zocchi, G. Basile, C. Cerrano, G. Bavestrello, M. Giovine, S. Bruzzone, L. Guida, A. Carpaneto, R. Magrassi, and C. Usai (2003)
J. Cell Sci. 116, 629-636
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Intracellular Ca2+ Stores by Multiple Ca2+-Releasing Messengers.

J. M. Cancela and O. H. Petersen (2002)
Diabetes 51, S349-357
 |  Abstract »  |  Full Text »  |  PDF »

Recent Advances in the Okamoto Model: The CD38-Cyclic ADP-Ribose Signal System and the Regenerating Gene Protein (Reg)-Reg Receptor System in {beta}-Cells.

H. Okamoto and S. Takasawa (2002)
Diabetes 51, S462-473
 |  Abstract »  |  Full Text »  |  PDF »

Nitric oxide inhibits ADP-ribosyl cyclase through a cGMP-independent pathway in airway smooth muscle.

T. A. White, T. F. Walseth, and M. S. Kannan (2002)
Am J Physiol Lung Cell Mol Physiol 283, L1065-L1071
 |  Abstract »  |  Full Text »  |  PDF »

The Ryanodine Receptor Calcium Channel of {beta}-Cells: Molecular Regulation and Physiological Significance.

M. S. Islam (2002)
Diabetes 51, 1299-1309
 |  Abstract »  |  Full Text »  |  PDF »

A novel mechanism for coupling cellular intermediary metabolism to cytosolic Ca2+ signaling via CD38/ADP-ribosyl cyclase, a putative intracellular NAD+ sensor.

L. SUN, O. A. ADEBANJO, A. KOVAL, H. K. ANANDATHEERTHAVARADA, J. IQBAL, X. Y. WU, B. S. MOONGA, X. B. WU, G. BISWAS, P. J. R. BEVIS, et al. (2002)
FASEB J 16, 302-314
 |  Abstract »  |  Full Text »  |  PDF »

Antidiabetic Effect of a Prodrug of Cysteine, L-2-Oxothiazolidine-4-carboxylic Acid, through CD38 Dimerization and Internalization.

M.-K. Han, S.-J. Kim, Y.-R. Park, Y.-M. Shin, H.-J. Park, K.-J. Park, K.-H. Park, H.-K. Kim, S.-I. Jang, N.-H. An, et al. (2002)
J. Biol. Chem. 277, 5315-5321
 |  Abstract »  |  Full Text »  |  PDF »

Control Mechanisms of the Oscillations of Insulin Secretion In Vitro and In Vivo.

P. Gilon, M. A. Ravier, J.-C. Jonas, and J.-C. Henquin (2002)
Diabetes 51, S144-151
 |  Abstract »  |  Full Text »  |  PDF »

Dynamic Imaging of Endoplasmic Reticulum Ca2+ Concentration in Insulin-Secreting MIN6 Cells Using Recombinant Targeted Cameleons: Roles of Sarco(endo)plasmic Reticulum Ca2+-ATPase (SERCA)-2 and Ryanodine Receptors.

A. Varadi and G. A. Rutter (2002)
Diabetes 51, S190-201
 |  Abstract »  |  Full Text »  |  PDF »

The temperature-signaling cascade in sponges involves a heat-gated cation channel, abscisic acid, and cyclic ADP-ribose.

E. Zocchi, A. Carpaneto, C. Cerrano, G. Bavestrello, M. Giovine, S. Bruzzone, L. Guida, L. Franco, and C. Usai (2001)
PNAS 98, 14859-14864
 |  Abstract »  |  Full Text »  |  PDF »

Increase of cGMP, cADP-ribose and inositol 1,4,5-trisphosphate preceding Ca2+ transients in fertilization of sea urchin eggs.

R. Kuroda, K. Kontani, Y. Kanda, T. Katada, T. Nakano, Y.-i. Satoh, N. Suzuki, and H. Kuroda (2001)
Development 128, 4405-4414
 |  Abstract »  |  Full Text »  |  PDF »

cADP-ribose/ryanodine channel/Ca2+-release signal transduction pathway in mesangial cells.

A. N. K. Yusufi, J. Cheng, M. A. Thompson, T. P. Dousa, G. M. Warner, H. J. Walker, and J. P. Grande (2001)
Am J Physiol Renal Physiol 281, F91-F102
 |  Abstract »  |  Full Text »  |  PDF »

Human Anti-CD38 Autoantibodies Raise Intracellular Calcium and Stimulate Insulin Release in Human Pancreatic Islets.

A. Antonelli, G. Baj, P. Marchetti, P. Fallahi, N. Surico, C. Pupilli, F. Malavasi, and E. Ferrannini (2001)
Diabetes 50, 985-991
 |  Abstract »  |  Full Text »

Autoantibody Response to CD38 in Caucasian Patients With Type 1 and Type 2 Diabetes: Immunological and Genetic Characterization.

R. Mallone, E. Ortolan, G. Baj, A. Funaro, S. Giunti, E. Lillaz, F. Saccucci, M. Cassader, P. Cavallo-Perin, and F. Malavasi (2001)
Diabetes 50, 752-762
 |  Abstract »  |  Full Text »

cADP-ribose activates reconstituted ryanodine receptors from coronary arterial smooth muscle.

P.-L. Li, W.-X. Tang, H. H. Valdivia, A.-P. Zou, and W. B. Campbell (2001)
Am J Physiol Heart Circ Physiol 280, H208-H215
 |  Abstract »  |  Full Text »  |  PDF »

Nitric oxide inhibits Ca2+ mobilization through cADP-ribose signaling in coronary arterial smooth muscle cells.

J.-Z. Yu, D. X. Zhang, A.-P. Zou, W. B. Campbell, and P.-L. Li (2000)
Am J Physiol Heart Circ Physiol 279, H873-H881
 |  Abstract »  |  Full Text »  |  PDF »

Extracellular cyclic ADP-ribose increases intracellular free calcium concentration and stimulates proliferation of human hemopoietic progenitors.

M. PODESTÀ, E. ZOCCHI, A. PITTO, C. USAI, L. FRANCO, S. BRUZZONE, L. GUIDA, A. BACIGALUPO, D. T. SCADDEN, T. F. WALSETH, et al. (2000)
FASEB J 14, 680-690
 |  Abstract »  |  Full Text »

Direct Interaction of the CD38 Cytoplasmic Tail and the Lck SH2 Domain. CD38 TRANSDUCES T CELL ACTIVATION SIGNALS THROUGH ASSOCIATED Lck.

Y.-S. Cho, M.-K. Han, Y. B. Choi, Y. Yun, J. Shin, and U.-H. Kim (2000)
J. Biol. Chem. 275, 1685-1690
 |  Abstract »  |  Full Text »  |  PDF »

Functional visualization of the separate but interacting calcium stores sensitive to NAADP and cyclic ADP-ribose.

H. Lee and R Aarhus (2000)
J. Cell Sci. 113, 4413-4420
 |  Abstract »  |  PDF »

Induction of Hippocampal LTD Requires Nitric-Oxide-Stimulated PKG Activity and Ca2+ Release From Cyclic ADP-Ribose-Sensitive Stores.

M. Reyes-Harde, B. V. L. Potter, A. Galione, and P. K. Stanton (1999)
J Neurophysiol 82, 1569-1576
 |  Abstract »  |  Full Text »  |  PDF »

cAMP-dependent Mobilization of Intracellular Ca2+ Stores by Activation of Ryanodine Receptors in Pancreatic beta -Cells. A Ca2+ SIGNALING SYSTEM STIMULATED BY THE INSULINOTROPIC HORMONE GLUCAGON-LIKE PEPTIDE-1-(7-37).

G. G. Holz, C. A. Leech, R. S. Heller, M. Castonguay, and J. F. Habener (1999)
J. Biol. Chem. 274, 14147-14156
 |  Abstract »  |  Full Text »  |  PDF »

CD38 Disruption Impairs Glucose-induced Increases in Cyclic ADP-ribose, [Ca2+]i, and Insulin Secretion.

I. Kato, Y. Yamamoto, M. Fujimura, N. Noguchi, S. Takasawa, and H. Okamoto (1999)
J. Biol. Chem. 274, 1869-1872
 |  Abstract »  |  Full Text »  |  PDF »

The transmembrane glycoprotein CD38 is a catalytically active transporter responsible for generation and influx of the second messenger cyclic ADP-ribose across membranes.

L. Franco, L. Guida, S. Bruzzone, E. Zocchi, C. Usai, and A. D. Flora (1998)
FASEB J 12, 1507-1520
 |  Abstract »  |  Full Text »

Progressive Pancreatic Islet Hyperplasia in the Islet-Targeted, Parathyroid Hormone-Related Protein-Overexpressing Mouse.

S. E. Porter, R. L. Sorenson, P. Dann, A. Garcia-Ocana, A. F. Stewart, and R. C. Vasavada (1998)
Endocrinology 139, 3743-3751
 |  Abstract »  |  Full Text »  |  PDF »

Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.

T. Miki, K. Nagashima, F. Tashiro, K. Kotake, H. Yoshitomi, A. Tamamoto, T. Gonoi, T. Iwanaga, J.-i. Miyazaki, and S. Seino (1998)
PNAS 95, 10402-10406
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of KCa-channel activity by cyclic ADP-ribose and ADP-ribose in coronary arterial smooth muscle.

P.-L. Li, A.-P. Zou, and W. B. Campbell (1998)
Am J Physiol Heart Circ Physiol 275, H1002-H1010
 |  Abstract »  |  Full Text »  |  PDF »

In situ activation of the type 2 ryanodine receptor in pancreatic beta cells requires cAMP-dependent phosphorylation.

M. S. Islam, I. Leibiger, B. Leibiger, D. Rossi, V. Sorrentino, T. J. Ekstrom, H. Westerblad, F. H. Andrade, and P.-O. Berggren (1998)
PNAS 95, 6145-6150
 |  Abstract »  |  Full Text »  |  PDF »

CD38 is functionally dependent on the TCR/CD3 complex in human T cells.

M. Morra, M. Zubiaur, C. Terhorst, J. Sancho, and F. Malavasi (1998)
FASEB J 12, 581-592
 |  Abstract »  |  Full Text »

Expression of CD38 Increases Intracellular Calcium Concentration and Reduces Doubling Time in HeLa and 3T3 Cells.

E. Zocchi, A. Daga, C. Usai, L. Franco, L. Guida, S. Bruzzone, A. Costa, C. Marchetti, and A. De Flora (1998)
J. Biol. Chem. 273, 8017-8024
 |  Abstract »  |  Full Text »  |  PDF »

Cyclic ADP-ribose and calcium-induced calcium release regulate neurotransmitter release at a cholinergic synapse of Aplysia.

J-P Mothet, P Fossier, F-M Meunier, J Stinnakre, L Tauc, and G Baux (1998)
J. Physiol. 507, 405-414
 |  Abstract »  |  Full Text »  |  PDF »

Cyclic ADP-ribose and Inositol 1,4,5-Trisphosphate as Alternate Second Messengers for Intracellular Ca2+ Mobilization in Normal and Diabetic beta -Cells.

S. Takasawa, T. Akiyama, K. Nata, M. Kuroki, A. Tohgo, N. Noguchi, S. Kobayashi, I. Kato, T. Katada, and H. Okamoto (1998)
J. Biol. Chem. 273, 2497-2500
 |  Abstract »  |  Full Text »  |  PDF »

Muscarinic Receptor-mediated Dual Regulation of ADP-ribosyl Cyclase in NG108-15 Neuronal Cell Membranes.

H. Higashida, S. Yokoyama, M. Hashii, M. Taketo, M. Higashida, T. Takayasu, T. Ohshima, S. Takasawa, H. Okamoto, and M. Noda (1997)
J. Biol. Chem. 272, 31272-31277
 |  Abstract »  |  Full Text »  |  PDF »

Stimulation of Cyclic ADP-ribose Synthesis by Acetylcholine and Its Role in Catecholamine Release in Bovine Adrenal Chromaffin Cells.

K. Morita, S. Kitayama, and T. Dohi (1997)
J. Biol. Chem. 272, 21002-21009
 |  Abstract »  |  Full Text »  |  PDF »

Role of Cyclic ADP-Ribose in ATP-activated Potassium Currents in Alveolar Macrophages.

S. Ebihara, T. Sasaki, W. Hida, Y. Kikuchi, T. Oshiro, S. Shimura, S. Takasawa, H. Okamoto, A. Nishiyama, N. Akaike, et al. (1997)
J. Biol. Chem. 272, 16023-16029
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Ca2+-Dependent Currents in Dorsal Root Ganglion Neurons by Metabotropic Glutamate Receptors and Cyclic ADP-Ribose Precursors.

J. H. Crawford, J. F. Wootton, G. R. Seabrook, and R. H. Scott (1997)
J Neurophysiol 77, 2573-2584
 |  Abstract »  |  Full Text »  |  PDF »

Ca2+ Entry Induced by Cyclic ADP-ribose in Intact T-Lymphocytes.

A. H. Guse, I. Berg, C. P. da Silva, B. V.L. Potter, and G. W. Mayr (1997)
J. Biol. Chem. 272, 8546-8550
 |  Abstract »  |  Full Text »  |  PDF »

The Sarcoplasmic Reticulum Ca2+ Channel/Ryanodine Receptor: Modulation by Endogenous Effectors, Drugs and Disease States.

R. Zucchi and S. Ronca-Testoni (1997)
Pharmacol. Rev. 49, 1-52
 |  Abstract »  |  Full Text »  |  PDF »

Lysine 129of CD38 (ADP-ribosyl Cyclase/Cyclic ADP-ribose Hydrolase) Participates in the Binding of ATP to Inhibit the Cyclic ADP-ribose Hydrolase.

A. Tohgo, H. Munakata, S. Takasawa, K. Nata, T. Akiyama, N. Hayashi, and H. Okamoto (1997)
J. Biol. Chem. 272, 3879-3882
 |  Abstract »  |  Full Text »  |  PDF »

Cyclic ADP-ribose Binds to FK506-binding Protein 12.6to Release Ca2+ from Islet Microsomes.

N. Noguchi, S. Takasawa, K. Nata, A. Tohgo, I. Kato, F. Ikehata, H. Yonekura, and H. Okamoto (1997)
J. Biol. Chem. 272, 3133-3136
 |  Abstract »  |  Full Text »  |  PDF »

Extracellular Synthesis of cADP-Ribose from Nicotinamide-Adenine Dinucleotide by Rat Cortical Astrocytes in Culture.

L. Pawlikowska, S. E. Cottrell, M. B. Harms, Y. Li, and P. A. Rosenberg (1996)
J. Neurosci. 16, 5372-5381
 |  Abstract »  |  Full Text »  |  PDF »

Insulin Exocytosis and Glucose-mediated Increase in Cytoplasmic Free Ca2+ Concentration in the Pancreatic beta -Cell Are Independent of Cyclic ADP-ribose.

D.-L. Webb, Md. S. Islam, A. M. Efanov, G. Brown, M. Kohler, O. Larsson, and P.-O. Berggren (1996)
J. Biol. Chem. 271, 19074-19079
 |  Abstract »  |  Full Text »  |  PDF »

Post-translational Modification of CD38 Protein into a High Molecular Weight Form Alters Its Catalytic Properties.

S. Umar, F. Malavasi, and K. Mehta (1996)
J. Biol. Chem. 271, 15922-15927
 |  Abstract »  |  Full Text »  |  PDF »

Cyclic ADP-Ribose Does Not Regulate Sarcoplasmic Reticulum Ca2+ Release in Intact Cardiac Myocytes.

X. Guo, M. A. Laflamme, and P. L. Becker (1996)
Circ. Res. 79, 147-151
 |  Abstract »  |  Full Text »

Functional Expression and Signaling Properties of Cloned Human Parathyroid Hormone Receptor in Xenopus Oocytes.

Y. Tong, J. Zull, and L. Yu (1996)
J. Biol. Chem. 271, 8183-8191
 |  Abstract »  |  Full Text »  |  PDF »

2`-Phospho-Cyclic ADP-ribose, a Calcium-mobilizing Agent Derived from NADP.

C. Q. Vu, P.-J. Lu, C.-S. Chen, and M. K. Jacobson (1996)
J. Biol. Chem. 271, 4747-4754
 |  Abstract »  |  Full Text »  |  PDF »

Nitric Oxide-induced Mobilization of Intracellular Calcium via the Cyclic ADP-ribose Signaling Pathway.

N. Willmott, J. K. Sethi, T. F. Walseth, H. C. Lee, A. M. White, and A. Galione (1996)
J. Biol. Chem. 271, 3699-3705
 |  Abstract »  |  Full Text »  |  PDF »

Regulatory Role of CD38 (ADP-ribosyl Cyclase/Cyclic ADP-ribose Hydrolase) in Insulin Secretion by Glucose in Pancreatic beta Cells.

I. Kato, S. Takasawa, A. Akabane, O. Tanaka, H. Abe, T. Takamura, Y. Suzuki, K. Nata, H. Yonekura, T. Yoshimoto, et al. (1995)
J. Biol. Chem. 270, 30045-30050
 |  Abstract »  |  Full Text »  |  PDF »

Agonist-stimulated Cyclic ADP Ribose.

J. F. Kuemmerle and G. M. Makhlouf (1995)
J. Biol. Chem. 270, 25488-25494
 |  Abstract »  |  Full Text »  |  PDF »

Ryanodine Receptor-Ankyrin Interaction Regulates Internal Ca[IMAGE] Release in Mouse T-lymphoma Cells.

L. Y. W. Bourguignon, A. Chu, H. Jin, and N. R. Brandt (1995)
J. Biol. Chem. 270, 17917-17922
 |  Abstract »  |  Full Text »  |  PDF »

Glutathionylspermidine Metabolism in Escherichia coli.

J. M. BollingerJr., D. S. Kwon, G. W. Huisman, R. Kolter, and C. T. Walsh (1995)
J. Biol. Chem. 270, 14031-14041
 |  Abstract »  |  Full Text »  |  PDF »

Release of Ca2+ from individual plant vacuoles by both InsP3 and cyclic ADP-ribose.

G. Allen, Muir SR, and D Sanders (1995)
Science 268, 735-737
 |  Abstract »  |  PDF »

Identification of Gangliosides as Inhibitors of ADP-ribosyltransferases of Pertussis Toxin and Exoenzyme C3 from Clostridium botulinum.

M. Hara-Yokoyama, Y. Hirabayashi, F. Irie, B. Syuto, K. Moriishi, H. Sugiya, and S. Furuyama (1995)
J. Biol. Chem. 270, 8115-8121
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.

T Ayabe, G. Kopf, and R. Schultz (1995)
Development 121, 2233-2244
 |  Abstract »  |  PDF »

Formation and hydrolysis of cyclic ADP-ribose catalyzed by lymphocyte antigen CD38.

M Howard, J. Grimaldi, J. Bazan, F. Lund, L Santos-Argumedo, R. Parkhouse, T. Walseth, and H. Lee (1993)
Science 262, 1056-1059
 |  Abstract »  |  PDF »

Cyclic ADP-ribose in beta cells.

M. Islam, O Larsson, and P. Berggren (1993)
Science 262, 584-586
 |  PDF »

Synthesis and degradation of cyclic ADP-ribose by NAD glycohydrolases.

H Kim, E. Jacobson, and M. Jacobson (1993)
Science 261, 1330-1333
 |  Abstract »  |  PDF »

Cyclic ADP-ribose: a new way to control calcium.

A Galione (1993)
Science 259, 325-326
 |  PDF »

Identification of Cyclic ADP-ribose-dependent Mechanisms in Pancreatic Muscarinic Ca2+ Signaling Using CD38 Knockout Mice.

Y. Fukushi, I. Kato, S. Takasawa, T. Sasaki, B. H. Ong, M. Sato, A. Ohsaga, K. Sato, K. Shirato, H. Okamoto, et al. (2001)
J. Biol. Chem. 276, 649-655
 |  Abstract »  |  Full Text »  |  PDF »

Functional switching of GABAergic synapses by ryanodine receptor activation.

M.-K. Sun, T. J. Nelson, and D. L. Alkon (2000)
PNAS 97, 12300-12305
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Reg gene, a gene for insulin-producing beta -cell regeneration: Poly(ADP-ribose) polymerase binds Reg promoter and regulates the transcription by autopoly(ADP-ribosyl)ation.

T. Akiyama, S. Takasawa, K. Nata, S. Kobayashi, M. Abe, N. J. Shervani, T. Ikeda, K. Nakagawa, M. Unno, S. Matsuno, et al. (2001)
PNAS 98, 48-53
 |  Abstract »  |  Full Text »  |  PDF »

Dense core secretory vesicles revealed as a dynamic Ca2+ store in neuroendocrine cells with a vesicle-associated membrane protein aequorin chimaera.

K. J. Mitchell, P. Pinton, A. Varadi, C. Tacchetti, E. K. Ainscow, T. Pozzan, R. Rizzuto, and G. A. Rutter (2001)
J. Cell Biol. 155, 41-52
 |  Abstract »  |  Full Text »  |  PDF »

Role of ADP-ribose in 11,12-EET-induced activation of KCa channels in coronary arterial smooth muscle cells.

P.-L. Li, D. X. Zhang, Z.-D. Ge, and W. B. Campbell (2002)
Am J Physiol Heart Circ Physiol 282, H1229-H1236
 |  Abstract »  |  Full Text »  |  PDF »

To Advertise   |   Find Products