Science 11 December 1992: Vol. 258. no. 5089, pp. 1808 - 1812 DOI: 10.1126/science.1281555

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Articles

Amino Acid Residues Required for Physical and Cooperative Transcriptional Interaction of STAT3 and AP-1 Proteins c-Jun and c-Fos.

M. Ginsberg, E. Czeko, P. Muller, Z. Ren, X. Chen, and J. E. Darnell Jr. (2007)
Mol. Cell. Biol. 27, 6300-6308
 |  Abstract »  |  Full Text »  |  PDF »

Differential Effects of CpG DNA on IFN-beta Induction and STAT1 Activation in Murine Macrophages versus Dendritic Cells: Alternatively Activated STAT1 Negatively Regulates TLR Signaling in Macrophages.

K. Schroder, M. Spille, A. Pilz, J. Lattin, K. A. Bode, K. M. Irvine, A. D. Burrows, T. Ravasi, H. Weighardt, K. J. Stacey, et al. (2007)
J. Immunol. 179, 3495-3503
 |  Abstract »  |  Full Text »  |  PDF »

The Interferons: 50 Years after Their Discovery, There Is Much More to Learn.

S. Pestka (2007)
J. Biol. Chem. 282, 20047-20051
 |  Abstract »  |  Full Text »  |  PDF »

JAK-STAT Signaling: From Interferons to Cytokines.

C. Schindler, D. E. Levy, and T. Decker (2007)
J. Biol. Chem. 282, 20059-20063
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Stat2-Dependent Regulation of MHC Class II Expression.

W. Zhao, E. N. Cha, C. Lee, C. Y. Park, and C. Schindler (2007)
J. Immunol. 179, 463-471
 |  Abstract »  |  Full Text »  |  PDF »

STAT1 Activation-Induced Apoptosis of Esophageal Squamous Cell Carcinoma Cells In Vivo.

J. Kaganoi, G. Watanabe, M. Okabe, S. Nagatani, A. Kawabe, Y. Shimada, M. Imamura, and Y. Sakai (2007)
Ann. Surg. Oncol. 14, 1405-1415
 |  Abstract »  |  Full Text »  |  PDF »

Downregulation of Gamma Interferon Receptor 1 by Kaposi's Sarcoma-Associated Herpesvirus K3 and K5.

Q. Li, R. Means, S. Lang, and J. U. Jung (2007)
J. Virol. 81, 2117-2127
 |  Abstract »  |  Full Text »  |  PDF »

Stat1 and SUMO modification.

L. Song, S. Bhattacharya, A. A. Yunus, C. D. Lima, and C. Schindler (2006)
Blood 108, 3237-3244
 |  Abstract »  |  Full Text »  |  PDF »

Cytokine Receptors and Jak-STAT Signaling.

C. Schindler (2006)
Sci. STKE 2006, tr7
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Ebola Virus VP24 Binds Karyopherin {alpha}1 and Blocks STAT1 Nuclear Accumulation..

St. P. Reid, L. W. Leung, A. L. Hartman, O. Martinez, M. L. Shaw, C. Carbonnelle, V. E. Volchkov, S. T. Nichol, and C. F. Basler (2006)
J. Virol. 80, 5156-5167
 |  Abstract »  |  Full Text »  |  PDF »

Human Complete Stat-1 Deficiency Is Associated with Defective Type I and II IFN Responses In Vitro but Immunity to Some Low Virulence Viruses In Vivo..

A. Chapgier, R. F. Wynn, E. Jouanguy, O. Filipe-Santos, S. Zhang, J. Feinberg, K. Hawkins, J.-L. Casanova, and P. D. Arkwright (2006)
J. Immunol. 176, 5078-5083
 |  Abstract »  |  Full Text »  |  PDF »

IFN-type-I-mediated signaling is regulated by modulation of STAT2 nuclear export.

T. Frahm, H. Hauser, and M. Koster (2006)
J. Cell Sci. 119, 1092-1104
 |  Abstract »  |  Full Text »  |  PDF »

Constitutive tyrosine and serine phosphorylation of STAT4 in T-cells transformed with HTLV-I.

T. Higashi, J. Tsukada, Y. Yoshida, T. Mizobe, F. Mouri, Y. Minami, H. Morimoto, and Y. Tanaka (2005)
Genes Cells 10, 1153-1162
 |  Abstract »  |  Full Text »  |  PDF »

Urocortin 2 Suppresses Host Resistance to Listeria monocytogenes Infection via Up-Regulation of Interleukin-10.

H. Sashinami, K. Kageyama, T. Suda, and A. Nakane (2005)
Endocrinology 146, 5003-5011
 |  Abstract »  |  Full Text »  |  PDF »

Physiological and Receptor-selective Retinoids Modulate Interferon {gamma} Signaling by Increasing the Expression, Nuclear Localization, and Functional Activity of Interferon Regulatory Factor-1.

X. M. Luo and A. C. Ross (2005)
J. Biol. Chem. 280, 36228-36236
 |  Abstract »  |  Full Text »  |  PDF »

Up-Regulation of the JAK/STAT1 Signal Pathway during Chlamydia trachomatis Infection.

S. P. Lad, E. Y. Fukuda, J. Li, L. M. de la Maza, and E. Li (2005)
J. Immunol. 174, 7186-7193
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Interferon-Mediated Antiviral Activity by Murine Gammaherpesvirus 68 Latency-Associated M2 Protein.

X. Liang, Y. C. Shin, R. E. Means, and J. U. Jung (2004)
J. Virol. 78, 12416-12427
 |  Abstract »  |  Full Text »  |  PDF »

PIASy-Deficient Mice Display Modest Defects in IFN and Wnt Signaling.

W. Roth, C. Sustmann, M. Kieslinger, A. Gilmozzi, D. Irmer, E. Kremmer, C. Turck, and R. Grosschedl (2004)
J. Immunol. 173, 6189-6199
 |  Abstract »  |  Full Text »  |  PDF »

The ENCODE (ENCyclopedia Of DNA Elements) Project.

The ENCODE Project Consortium (2004)
Science 306, 636-640
 |  Abstract »  |  Full Text »  |  PDF »

Differential roles of STAT1{alpha} and STAT1{beta} in fludarabine-induced cell cycle arrest and apoptosis in human B cells.

F. Baran-Marszak, J. Feuillard, I. Najjar, C. Le Clorennec, J.-M. Bechet, I. Dusanter-Fourt, G. W. Bornkamm, M. Raphael, and R. Fagard (2004)
Blood 104, 2475-2483
 |  Abstract »  |  Full Text »  |  PDF »

An Indispensable Role for STAT1 in IL-27-Induced T-bet Expression but Not Proliferation of Naive CD4+ T Cells.

S. Kamiya, T. Owaki, N. Morishima, F. Fukai, J. Mizuguchi, and T. Yoshimoto (2004)
J. Immunol. 173, 3871-3877
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of a Dipeptide Motif Regulating IFN-{gamma} Receptor 2 Plasma Membrane Accumulation and IFN-{gamma} Responsiveness.

S. D. Rosenzweig, O. M. Schwartz, M. R. Brown, T. L. Leto, and S. M. Holland (2004)
J. Immunol. 173, 3991-3999
 |  Abstract »  |  Full Text »  |  PDF »

Induction of IgG2a Class Switching in B Cells by IL-27.

T. Yoshimoto, K. Okada, N. Morishima, S. Kamiya, T. Owaki, M. Asakawa, Y. Iwakura, F. Fukai, and J. Mizuguchi (2004)
J. Immunol. 173, 2479-2485
 |  Abstract »  |  Full Text »  |  PDF »

A GATA Factor Mediates Cell Type-Restricted Induction of HLA-E Gene Transcription by Gamma Interferon.

D. M. Barrett, K. S. Gustafson, J. Wang, S. Z. Wang, and G. D. Ginder (2004)
Mol. Cell. Biol. 24, 6194-6204
 |  Abstract »  |  Full Text »  |  PDF »

Bile acids are essential for porcine enteric calicivirus replication in association with down-regulation of signal transducer and activator of transcription 1.

K.-O. Chang, S. V. Sosnovtsev, G. Belliot, Y. Kim, L. J. Saif, and K. Y. Green (2004)
PNAS 101, 8733-8738
 |  Abstract »  |  Full Text »  |  PDF »

The Role of Signal Transducer and Activator of Transcription Factors in Leukemogenesis.

D. W. Sternberg and D. G. Gilliland (2004)
J. Clin. Oncol. 22, 361-371
 |  Abstract »  |  Full Text »  |  PDF »

Differential Roles of C-terminal Activation Motifs in the Establishment of Stat6 Transcriptional Specificity.

S. Goenka, C. Marlar, U. Schindler, and M. Boothby (2003)
J. Biol. Chem. 278, 50362-50370
 |  Abstract »  |  Full Text »  |  PDF »

STAT3-dependent enhanceosome assembly and disassembly: synergy with GR for full transcriptional increase of the {alpha}2-macroglobulin gene.

L. Lerner, M. A. Henriksen, X. Zhang, and J. E. Darnell Jr. (2003)
Genes & Dev. 17, 2564-2577
 |  Abstract »  |  Full Text »  |  PDF »

Role for Nuclear Factor-{kappa}B and Signal Transducer and Activator of Transcription 1/Interferon Regulatory Factor-1 in Cytokine-Induced Endothelin-1 Release in Human Vascular Smooth Muscle Cells.

M. Woods, E. G. Wood, S. C. Bardswell, D. Bishop-Bailey, S. Barker, S. J. Wort, J. A. Mitchell, and T. D. Warner (2003)
Mol. Pharmacol. 64, 923-931
 |  Abstract »  |  Full Text »  |  PDF »

STATs Dimerize in the Absence of Phosphorylation.

J. Braunstein, S. Brutsaert, R. Olson, and C. Schindler (2003)
J. Biol. Chem. 278, 34133-34140
 |  Abstract »  |  Full Text »  |  PDF »

DNA binding controls inactivation and nuclear accumulation of the transcription factor Stat1.

T. Meyer, A. Marg, P. Lemke, B. Wiesner, and U. Vinkemeier (2003)
Genes & Dev. 17, 1992-2005
 |  Abstract »  |  Full Text »  |  PDF »

Ser727/Tyr701-phosphorylated Stat1 is required for the regulation of c-Myc, cyclins, and p27Kip1 associated with ATRA-induced G0/G1 arrest of U-937 cells.

A. Dimberg, I. Karlberg, K. Nilsson, and F. Oberg (2003)
Blood 102, 254-261
 |  Abstract »  |  Full Text »  |  PDF »

PIASx Is a Transcriptional Co-repressor of Signal Transducer and Activator of Transcription 4.

T. Arora, B. Liu, H. He, J. Kim, T. L. Murphy, K. M. Murphy, R. L. Modlin, and K. Shuai (2003)
J. Biol. Chem. 278, 21327-21330
 |  Abstract »  |  Full Text »  |  PDF »

The Epstein-Barr Virus SM Protein Induces STAT1 and Interferon-Stimulated Gene Expression.

V. Ruvolo, L. Navarro, C. E. Sample, M. David, S. Sung, and S. Swaminathan (2003)
J. Virol. 77, 3690-3701
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of Cellular Signaling Pathways: Prospects for Targeted Therapy in Hematological Malignancies.

F. Ravandi, M. Talpaz, and Z. Estrov (2003)
Clin. Cancer Res. 9, 535-550
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-gamma switches monocyte differentiation from dendritic cells to macrophages.

Y. Delneste, P. Charbonnier, N. Herbault, G. Magistrelli, G. Caron, J.-Y. Bonnefoy, and P. Jeannin (2003)
Blood 101, 143-150
 |  Abstract »  |  Full Text »  |  PDF »

In the presence of bone marrow stromal cells human multiple myeloma cells become independent of the IL-6/gp130/STAT3 pathway.

M. Chatterjee, D. Honemann, S. Lentzsch, K. Bommert, C. Sers, P. Herrmann, S. Mathas, B. Dorken, and R. C. Bargou (2002)
Blood 100, 3311-3318
 |  Abstract »  |  Full Text »  |  PDF »

IL-13 signal transduction in human monocytes: phosphorylation of receptor components, association with Jaks, and phosphorylation/activation of Stats.

B. Roy, A. Bhattacharjee, B. Xu, D. Ford, A. L. Maizel, and M. K. Cathcart (2002)
J. Leukoc. Biol. 72, 580-589
 |  Abstract »  |  Full Text »  |  PDF »

Activation of signal transducer and activator of transcription (STAT) 1 in human chronic inflammatory bowel disease.

S Schreiber, P Rosenstiel, J Hampe, S Nikolaus, B Groessner, A Schottelius, T Kuhbacher, J Hamling, U R Folsch, and D Seegert (2002)
Gut 51, 379-385
 |  Abstract »  |  Full Text »

Stat1-Vitamin D Receptor Interactions Antagonize 1,25-Dihydroxyvitamin D Transcriptional Activity and Enhance Stat1-Mediated Transcription.

M. Vidal, C. V. Ramana, and A. S. Dusso (2002)
Mol. Cell. Biol. 22, 2777-2787
 |  Abstract »  |  Full Text »  |  PDF »

Roles of Stat1, Stat2, and Interferon Regulatory Factor-9 (IRF-9) in Interferon Tau Regulation of IRF-1.

M. D. Stewart, Y. Choi, G. A. Johnson, L.-y. Yu-Lee, F. W. Bazer, and T. E. Spencer (2002)
Biol Reprod 66, 393-400
 |  Abstract »  |  Full Text »  |  PDF »

{gamma}-Interferon Signaling in Pancreatic {beta}-Cells Is Persistent but Can Be Terminated by Overexpression of Suppressor of Cytokine Signaling-1.

M. M.W. Chong, H. E. Thomas, and T. W.H. Kay (2001)
Diabetes 50, 2744-2751
 |  Abstract »  |  Full Text »  |  PDF »

GH Inhibits Interferon-{gamma}-Induced Signal Transducer and Activator of Transcription-1 Activation and Expression of the Inducible Isoform of Nitric Oxide Synthase in INS-1 Cells.

N. Sekine, S. Fukumoto, T. Ishikawa, T. Okazaki, and T. Fujita (2001)
Endocrinology 142, 3909-3916
 |  Abstract »  |  Full Text »  |  PDF »

Functional correction of FA-C cells with FANCC suppresses the expression of interferon {gamma}-inducible genes.

S. R. Fagerlie, J. Diaz, T. A. Christianson, K. McCartan, W. Keeble, G. R. Faulkner, and G. C. Bagby (2001)
Blood 97, 3017-3024
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-{{tau}} (IFN{{tau}}) Regulation of IFN-Stimulated Gene Expression in Cell Lines Lacking Specific IFN-Signaling Components.

M. D. Stewart, G. A. Johnson, F. W. Bazer, and T. E. Spencer (2001)
Endocrinology 142, 1786-1794
 |  Abstract »  |  Full Text »

Vaccinia Virus Blocks Gamma Interferon Signal Transduction: Viral VH1 Phosphatase Reverses Stat1 Activation.

P. Najarro, P. Traktman, and J. A. Lewis (2001)
J. Virol. 75, 3185-3196
 |  Abstract »  |  Full Text »

Organization and Functional Analysis of the Mouse Transporter Associated with Antigen Processing 2 Promoter.

E. Arons, V. Kunin, C. Schechter, and R. Ehrlich (2001)
J. Immunol. 166, 3942-3951
 |  Abstract »  |  Full Text »  |  PDF »

Impaired {{alpha}}-Interferon Signaling in Transitional Cell Carcinoma: Lack of p48 Expression in 5637 Cells.

S. F. Matin, R. R. Rackley, P. C. Sadhukhan, M. S. Kim, A. C. Novick, and S. K. Bandyopadhyay (2001)
Cancer Res. 61, 2261-2266
 |  Abstract »  |  Full Text »

Induction of Endothelial-Leukocyte Interaction by Interferon-{{gamma}} Requires Coactivation of Nuclear Factor-{{kappa}}B.

R. De Caterina, T. Bourcier, U. Laufs, V. La Fata, G. Lazzerini, A. S. Neish, P. Libby, and J. K. Liao (2001)
Arterioscler. Thromb. Vasc. Biol. 21, 227-232
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of STAT1 Nuclear Export by Jak1.

K. Mowen and M. David (2000)
Mol. Cell. Biol. 20, 7273-7281
 |  Abstract »  |  Full Text »

Impairment of STAT Activation by IL-12 in a Patient with Atypical Mycobacterial and Staphylococcal Infections.

J. A. Gollob, K. G. Veenstra, H. Jyonouchi, A. M. Kelly, P. Ferrieri, D. J. Panka, F. Altare, C. Fieschi, J.-L. Casanova, D. A. Frank, et al. (2000)
J. Immunol. 165, 4120-4126
 |  Abstract »  |  Full Text »  |  PDF »

Oncostatin M Stimulates the Growth of Dermal Fibroblasts Via a Mitogen-Activated Protein Kinase-Dependent Pathway.

H. Ihn and K. Tamaki (2000)
J. Immunol. 165, 2149-2155
 |  Abstract »  |  Full Text »  |  PDF »

A unique ISRE, in the TATA-less human Isg20 promoter, confers IRF-1-mediated responsiveness to both interferon type I and type II.

C. Gongora, G. Degols, L. Espert, T. D. Hua, and N. Mechti (2000)
Nucleic Acids Res. 28, 2333-2341
 |  Abstract »  |  Full Text »  |  PDF »

The gene for familial Mediterranean fever, MEFV, is expressed in early leukocyte development and is regulated in response to inflammatory mediators.

M. Centola, G. Wood, D. M. Frucht, J. Galon, M. Aringer, C. Farrell, D. W. Kingma, M. E. Horwitz, E. Mansfield, S. M. Holland, et al. (2000)
Blood 95, 3223-3231
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional regulation of the MHC II gene DRA in untransformed human thyrocytes.

Z. Wu, P. A. Biro, R. Mirakian, F. Curcio, F. S. Ambesi-Impiombato, and G. F. Bottazzo (2000)
Int. Immunol. 12, 405-413
 |  Abstract »  |  Full Text »  |  PDF »

Induction of E-Selectin Expression by Double-Stranded RNA and TNF-{alpha} Is Attenuated in Murine Aortic Endothelial Cells Derived from Double-Stranded RNA-Activated Kinase (PKR)-Null Mice.

S. K. Bandyopadhyay, C. A. de la Motte, and B. R. G. Williams (2000)
J. Immunol. 164, 2077-2083
 |  Abstract »  |  Full Text »  |  PDF »

The Role of Sp Family Members, Basic Krupple-Like Factor, and E Box Factors in the Basal and IFN-{gamma} Regulated Expression of the Human Complement C4 Promoter.

D. Ulgiati, L. S. Subrata, and L. J. Abraham (2000)
J. Immunol. 164, 300-307
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase C delta Associates with and Phosphorylates Stat3 in an Interleukin-6-dependent Manner.

N. Jain, T. Zhang, W. H. Kee, W. Li, and X. Cao (1999)
J. Biol. Chem. 274, 24392-24400
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Apoptosis in Myeloid Cells by Interferon Consensus Sequence–Binding Protein.

L. Gabriele, J. Phung, J. Fukumoto, D. Segal, I-M. Wang, P. Giannakakou, N. A. Giese, K. Ozato, and H. C. Morse , III (1999)
J. Exp. Med. 190, 411-422
 |  Abstract »  |  Full Text »  |  PDF »

Escape of Human Cytomegalovirus from HLA-DR-Restricted CD4+ T-Cell Response Is Mediated by Repression of Gamma Interferon-Induced Class II Transactivator Expression.

E. Le Roy, A. Mühlethaler-Mottet, C. Davrinche, B. Mach, and J.-L. Davignon (1999)
J. Virol. 73, 6582-6589
 |  Abstract »  |  Full Text »

Relation of TNF-related Apoptosis-inducing Ligand (TRAIL) Receptor and FLICE-inhibitory Protein Expression to TRAIL-induced Apoptosis of Melanoma.

X. D. Zhang, A. Franco, K. Myers, C. Gray, T. Nguyen, and P. Hersey (1999)
Cancer Res. 59, 2747-2753
 |  Abstract »  |  Full Text »  |  PDF »

Repression of IL-4-Induced Gene Expression by IFN-{gamma} Requires Stat1 Activation.

C. Venkataraman, S. Leung, A. Salvekar, H. Mano, and U. Schindler (1999)
J. Immunol. 162, 4053-4061
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of Endocytosis in Nuclear Factor IL-6(-/-) Macrophages Is Responsible for a High Susceptibility to Intracellular Bacterial Infection.

J. Pizarro-Cerda, M. Desjardins, E. Moreno, S. Akira, and J.-P. Gorvel (1999)
J. Immunol. 162, 3519-3526
 |  Abstract »  |  Full Text »  |  PDF »

A Functional DNA Binding Domain Is Required for Growth Hormone-induced Nuclear Accumulation of Stat5B.

J. Herrington, L. Rui, G. Luo, L.-y. Yu-Lee, and C. Carter-Su (1999)
J. Biol. Chem. 274, 5138-5145
 |  Abstract »  |  Full Text »  |  PDF »

Defective Induction of the Transcription Factor Interferon-StimulatedGene Factor-3 and Interferon {alpha} Insensitivity in Human Trophoblast Cells.

J. C. Cross, S. Lam, S. Yagel, and Z. Werb (1999)
Biol Reprod 60, 312-321
 |  Abstract »  |  Full Text »  |  PDF »

Signaling Pathways Mediated by the TNF- and Cytokine-Receptor Families Target a Common cis-Element of the IFN Regulatory Factor 1 Promoter.

S. Gupta, D. Xia, M. Jiang, S. Lee, and A. B. Pernis (1998)
J. Immunol. 161, 5997-6004
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of NF-{kappa}B, AP-1, NFAT, and STAT1 Nuclear Import in T Lymphocytes by Noninvasive Delivery of Peptide Carrying the Nuclear Localization Sequence of NF-{kappa}B p50.

T. R. Torgerson, A. D. Colosia, J. P. Donahue, Y.-Z. Lin, and J. Hawiger (1998)
J. Immunol. 161, 6084-6092
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Signal Transducers and Activators of Transcription 1 and 3 by Leukemia Inhibitory Factor, Oncostatin-M, and Interferon-gamma in Adipocytes.

J. M. Stephens, S. J. Lumpkin, and J. B. Fishman (1998)
J. Biol. Chem. 273, 31408-31416
 |  Abstract »  |  Full Text »  |  PDF »

Role of the STAT1-SH2 Domain and STAT2 in the Activation and Nuclear Translocation of STAT1.

K. Mowen and M. David (1998)
J. Biol. Chem. 273, 30073-30076
 |  Abstract »  |  Full Text »  |  PDF »

Autocrine/Paracrine IFN-{alpha}{beta} Mediates the Lipopolysaccharide-Induced Activation of Transcription Factor Stat1{alpha} in Mouse Macrophages: Pivotal Role of Stat1{alpha} in Induction of the Inducible Nitric Oxide Synthase Gene.

J. J. Gao, M. B. Filla, M. J. Fultz, S. N. Vogel, S. W. Russell, and W. J. Murphy (1998)
J. Immunol. 161, 4803-4810
 |  Abstract »  |  Full Text »  |  PDF »

Amino-terminal Signal Transducer and Activator of Transcription (STAT) Domains Regulate Nuclear Translocation and STAT Deactivation.

I. Strehlow and C. Schindler (1998)
J. Biol. Chem. 273, 28049-28056
 |  Abstract »  |  Full Text »  |  PDF »

Interferon Induction of TAP1 : The Phosphatase SHP-1 Regulates Crossover Between the IFN-{alpha}/ß and the IFN-{gamma} Signal-Transduction Pathways.

W. Min, J. S. Pober, and D. R. Johnson (1998)
Circ. Res. 83, 815-823
 |  Abstract »  |  Full Text »  |  PDF »

The cAMP-dependent Protein Kinase Site (Ser312) Enhances Dorsal Nuclear Import through Facilitating Nuclear Localization Sequence/Importin Interaction.

L. J. Briggs, D. Stein, J. Goltz, V. C. Corrigan, A. Efthymiadis, S. Hubner, and D. A. Jans (1998)
J. Biol. Chem. 273, 22745-22752
 |  Abstract »  |  Full Text »  |  PDF »

PRMT 3, a Type I Protein Arginine N-Methyltransferase That Differs from PRMT1 in Its Oligomerization, Subcellular Localization, Substrate Specificity, and Regulation.

J. Tang, J. D. Gary, S. Clarke, and H. R. Herschman (1998)
J. Biol. Chem. 273, 16935-16945
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase A-Mediated Inhibition of Gamma Interferon-Induced Tyrosine Phosphorylation of Janus Kinases and Latent Cytoplasmic Transcription Factors in Human Monocytes by Ehrlichia chaffeensis.

E. H. Lee and Y. Rikihisa (1998)
Infect. Immun. 66, 2514-2520
 |  Abstract »  |  Full Text »  |  PDF »

Signal transduction and activator of transcription (STAT) protein-dependent activation of angiotensinogen promoter: A cellular signal for hypertrophy in cardiac muscle.

E. Mascareno, M. Dhar, and M. A. Q. Siddiqui (1998)
PNAS 95, 5590-5594
 |  Abstract »  |  Full Text »  |  PDF »

Biphasic Activation of the JAK/STAT Pathway by Angiotensin II in Rat Cardiomyocytes.

H. Kodama, K. Fukuda, J. Pan, S. Makino, M. Sano, T. Takahashi, S. Hori, and S. Ogawa (1998)
Circ. Res. 82, 244-250
 |  Abstract »  |  Full Text »  |  PDF »

Lipoarabinomannan of Mycobacterium tuberculosis Promotes Protein Tyrosine Dephosphorylation and Inhibition of Mitogen-activated Protein Kinase in Human Mononuclear Phagocytes. ROLE OF THE Src HOMOLOGY 2 CONTAINING TYROSINE PHOSPHATASE 1.

K. L. Knutson, Z. Hmama, P. Herrera-Velit, R. Rochford, and N. E. Reiner (1998)
J. Biol. Chem. 273, 645-652
 |  Abstract »  |  Full Text »  |  PDF »

Human Herpesvirus 8 Encodes an Interferon Regulatory Factor (IRF) Homolog That Represses IRF-1-Mediated Transcription.

J. C. Zimring, S. Goodbourn, and M. K. Offermann (1998)
J. Virol. 72, 701-707
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Distinct Regions of 5' Flanking DNA That Mediate Constitutive, IFN-{gamma}, STAT1, and TGF-{beta}-Regulated Expression of the Class II Transactivator Gene.

J. F. Piskurich, Y. Wang, M. W. Linhoff, L. C. White, and J. P.-Y. Ting (1998)
J. Immunol. 160, 233-240
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Myeloma: Increasing Evidence for a Multistep Transformation Process.

M. Hallek, P. Leif Bergsagel, and K. C. Anderson (1998)
Blood 91, 3-21
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Specific Inhibition of Stat3 Signal Transduction by PIAS3.

C. D. Chung, J. Liao, B. Liu, X. Rao, P. Jay, P. Berta, and K. Shuai (1997)
Science 278, 1803-1805
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Leukemia Inhibitory Factor, a Potent Cardiac Hypertrophic Cytokine, Activates the JAK/STAT Pathway in Rat Cardiomyocytes.

H. Kodama, K. Fukuda, J. Pan, S. Makino, A. Baba, S. Hori, and S. Ogawa (1997)
Circ. Res. 81, 656-663
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Targeted Inhibition of Interferon-gamma -dependent Intercellular Adhesion Molecule-1 (ICAM-1) Expression Using Dominant-Negative Stat1.

M. J. Walter, D. C. Look, R. M. Tidwell, W. T. Roswit, and M. J. Holtzman (1997)
J. Biol. Chem. 272, 28582-28589
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Down-regulation of interferon gamma -activated STAT1 by UV light.

Y. Aragane, D. Kulms, T. A. Luger, and T. Schwarz (1997)
PNAS 94, 11490-11495
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Molecular Cloning of a New Interferon-induced PML Nuclear Body-associated Protein.

C. Gongora, G. David, L. Pintard, C. Tissot, T. D. Hua, A. Dejean, and N. Mechti (1997)
J. Biol. Chem. 272, 19457-19463
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Identification and Localization of a Skeletal Muscle Secrotonin 5-HT2A Receptor Coupled to the Jak/STAT Pathway.

I. Guillet-Deniau, A.-F. Burnol, and J. Girard (1997)
J. Biol. Chem. 272, 14825-14829
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Growth Hormone Stimulates Transcription of the Gene Encoding the Acid-Labile Subunit (ALS) of the Circulating Insulin-Like Growth Factor-Binding Protein Complex and ALS Promoter Activity in Rat Liver.

G. T. Ooi, F. J. Cohen, L. Y.-H. Tseng, M. M. Rechler, and Y. R. Boisclair (1997)
Mol. Endocrinol. 11, 997-1007
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A Common Pro-opiomelanocortin-binding Element Mediates Leukemia Inhibitory Factor and Corticotropin-releasing Hormone Transcriptional Synergy.

C. Bousquet, D. W. Ray, and S. Melmed (1997)
J. Biol. Chem. 272, 10551-10557
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Prolactin Regulation of Islet-Derived INS-1 Cells: Characteristics and Immunocytochemical Analysis of STAT5 Translocation.

L. E. Stout, A. M. Svensson, and R. L. Sorenson (1997)
Endocrinology 138, 1592-1603
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Synergistic Activation of the Human Type II 3beta -Hydroxysteroid Dehydrogenase/Delta 5-Delta 4 Isomerase Promoter by the Transcription Factor Steroidogenic Factor-1/Adrenal 4-binding Protein and Phorbol Ester.

S. Leers-Sucheta, K.-i. Morohashi, J. I. Mason, and M. H. Melner (1997)
J. Biol. Chem. 272, 7960-7967
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A Single STAT Recruitment Module in a Chimeric Cytokine Receptor Complex Is Sufficient for STAT Activation.

I. Behrmann, C. Janzen, C. Gerhartz, H. S.-V. de Leur, H. Hermanns, B. Heesel, L. Graeve, F. Horn, J. Tavernier, and P. C. Heinrich (1997)
J. Biol. Chem. 272, 5269-5274
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Interferon gamma -induced transcription of the murine ISGF3gamma (p48) gene is mediated by novel factors.

X. Weihua, V. Kolla, and D. V. Kalvakolanu (1997)
PNAS 94, 103-108
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The mouse transcription factor Stat4 is expressed in haploid male germ cells and is present in the perinuclear theca of spermatozoa.

G Herrada and D. Wolgemuth (1997)
J. Cell Sci. 110, 1543-1553
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Interferon-gamma -dependent Nuclear Import of Stat1 Is Mediated by the GTPase Activity of Ran/TC4.

T. Sekimoto, K. Nakajima, T. Tachibana, T. Hirano, and Y. Yoneda (1996)
J. Biol. Chem. 271, 31017-31020
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Nuclear Transport of Granzyme B (Fragmentin-2). DEPENDENCE ON PERFORIN IN VIVO AND CYTOSOLIC FACTORS IN VITRO.

D. A. Jans, P. Jans, L. J. Briggs, V. Sutton, and J. A. Trapani (1996)
J. Biol. Chem. 271, 30781-30789
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Stat3 Recruitment by Two Distinct Ligand-induced, Tyrosine-phosphorylated Docking Sites in the Interleukin-10 Receptor Intracellular Domain.

R. M. Weber-Nordt, J. K. Riley, A. C. Greenlund, K. W. Moore, J. E. Darnell, and R. D. Schreiber (1996)
J. Biol. Chem. 271, 27954-27961
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Interferon-gamma Induction of the Human Leukocyte Antigen-E Gene Is Mediated through Binding of a Complex Containing STAT1alpha to a Distinct Interferon-gamma -responsive Element.

K. S. Gustafson and G. D. Ginder (1996)
J. Biol. Chem. 271, 20035-20046
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Differential Activation of Acute Phase Response Factor/Stat3 and Stat1 via the Cytoplasmic Domain of the Interleukin 6 Signal Transducer gp130. II. Src HOMOLOGY SH2 DOMAINS DEFINE THE SPECIFICITY OF STAT FACTOR ACTIVATION.

U. Hemmann, C. Gerhartz, B. Heesel, J. Sasse, G. Kurapkat, J. Grotzinger, A. Wollmer, Z. Zhong, J. E. Darnell Jr., L. Graeve, et al. (1996)
J. Biol. Chem. 271, 12999-13007
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STAT3beta , a Splice Variant of Transcription Factor STAT3, Is a Dominant Negative Regulator of Transcription.

E. Caldenhoven (1996)
J. Biol. Chem. 271, 13221-13227
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