Science 20 November 1992: Vol. 258. no. 5086, pp. 1369 - 1372 DOI: 10.1126/science.1455233

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Articles

Structure and mechanism of IFN-{gamma} antagonism by an orthopoxvirus IFN-{gamma}-binding protein.

A. A. Nuara, L. J. Walter, N. J. Logsdon, S. I. Yoon, B. C. Jones, J. M. Schriewer, R. M. Buller, and M. R. Walter (2008)
PNAS 105, 1861-1866
 |  Abstract »  |  Full Text »  |  PDF »

An Ectromelia Virus Protein That Interacts with Chemokines through Their Glycosaminoglycan Binding Domain.

M. B. Ruiz-Arguello, V. P. Smith, G. S. V. Campanella, F. Baleux, F. Arenzana-Seisdedos, A. D. Luster, and A. Alcami (2008)
J. Virol. 82, 917-926
 |  Abstract »  |  Full Text »  |  PDF »

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures.

R. E. Randall and S. Goodbourn (2008)
J. Gen. Virol. 89, 1-47
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Variation in host susceptibility and infectiousness generated by co-infection: the myxoma-Trichostrongylus retortaeformis case in wild rabbits.

I. M Cattadori, R. Albert, and B. Boag (2007)
J R Soc Interface 4, 831-840
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M135R Is a Novel Cell Surface Virulence Factor of Myxoma Virus.

J. W. Barrett, J. Sypula, F. Wang, L. R. Alston, Z. Shao, X. Gao, T. S. Irvine, and G. McFadden (2007)
J. Virol. 81, 106-114
 |  Abstract »  |  Full Text »  |  PDF »

Vaccinia virus kelch protein A55 is a 64 kDa intracellular factor that affects virus-induced cytopathic effect and the outcome of infection in a murine intradermal model.

P. M. Beard, G. C. Froggatt, and G. L. Smith (2006)
J. Gen. Virol. 87, 1521-1529
 |  Abstract »  |  Full Text »  |  PDF »

Ectromelia virus: the causative agent of mousepox.

D. J. Esteban and R. M. L. Buller (2005)
J. Gen. Virol. 86, 2645-2659
 |  Abstract »  |  Full Text »  |  PDF »

Interferon function is not required for recovery from a secondary poxvirus infection.

V. Panchanathan, G. Chaudhri, and G. Karupiah (2005)
PNAS 102, 12921-12926
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of Soluble Cytokine Receptor Generation.

S. J. Levine (2004)
J. Immunol. 173, 5343-5348
 |  Abstract »  |  Full Text »  |  PDF »

Secreted Immunomodulatory Viral Proteins as Novel Biotherapeutics.

A. Lucas and G. McFadden (2004)
J. Immunol. 173, 4765-4774
 |  Abstract »  |  Full Text »  |  PDF »

Blocking of the Alpha Interferon-Induced Jak-Stat Signaling Pathway by Japanese Encephalitis Virus Infection.

R.-J. Lin, C.-L. Liao, E. Lin, and Y.-L. Lin (2004)
J. Virol. 78, 9285-9294
 |  Abstract »  |  Full Text »  |  PDF »

Cowpox virus CrmA, Myxoma virus SERP2 and baculovirus P35 are not functionally interchangeable caspase inhibitors in poxvirus infections.

R. Nathaniel, A. L. MacNeill, Y.-X. Wang, P. C. Turner, and R. W. Moyer (2004)
J. Gen. Virol. 85, 1267-1278
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-18 and glycosaminoglycan binding by a protein encoded by Variola virus.

D. J. Esteban, A. A. Nuara, and R. M. L. Buller (2004)
J. Gen. Virol. 85, 1291-1299
 |  Abstract »  |  Full Text »  |  PDF »

Human cytomegalovirus UL83-coded pp65 virion protein inhibits antiviral gene expression in infected cells.

E. P. Browne and T. Shenk (2003)
PNAS 100, 11439-11444
 |  Abstract »  |  Full Text »  |  PDF »

A secreted high-affinity inhibitor of human TNF from Tanapox virus.

C. R. Brunetti, M. Paulose-Murphy, R. Singh, J. Qin, J. W. Barrett, A. Tardivel, P. Schneider, K. Essani, and G. McFadden (2003)
PNAS 100, 4831-4836
 |  Abstract »  |  Full Text »  |  PDF »

Interleukins in Atherosclerosis: Molecular Pathways and Therapeutic Potential.

J. H. Von der Thusen, J. Kuiper, T. J. C. Van Berkel, and E. A. L. Biessen (2003)
Pharmacol. Rev. 55, 133-166
 |  Abstract »  |  Full Text »  |  PDF »

An Interferon-gamma -binding Protein of Novel Structure Encoded by the Fowlpox Virus.

F. Puehler, H. Schwarz, B. Waidner, J. Kalinowski, B. Kaspers, S. Bereswill, and P. Staeheli (2003)
J. Biol. Chem. 278, 6905-6911
 |  Abstract »  |  Full Text »  |  PDF »

The vaccinia virus C12L protein inhibits mouse IL-18 and promotes virus virulence in the murine intranasal model.

J. A. Symons, E. Adams, D. C. Tscharke, P. C. Reading, H. Waldmann, and G. L. Smith (2002)
J. Gen. Virol. 83, 2833-2844
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A study of the vaccinia virus interferon-{gamma} receptor and its contribution to virus virulence.

J. A. Symons, D. C. Tscharke, N. Price, and G. L. Smith (2002)
J. Gen. Virol. 83, 1953-1964
 |  Abstract »  |  Full Text »  |  PDF »

Viral chemokine-binding proteins.

B. T. Seet and G. McFadden (2002)
J. Leukoc. Biol. 72, 24-34
 |  Abstract »  |  Full Text »  |  PDF »

Cowpox virus encodes a fifth member of the tumor necrosis factor receptor family: A soluble, secreted CD30 homologue.

J. F. Panus, C. A. Smith, C. A. Ray, T. D. Smith, D. D. Patel, and D. J. Pickup (2002)
PNAS 99, 8348-8353
 |  Abstract »  |  Full Text »  |  PDF »

The vaccinia virus soluble interferon-{gamma} receptor is a homodimer.

A. Alcami and G. L. Smith (2002)
J. Gen. Virol. 83, 545-549
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Interferons by Ectromelia Virus.

V. P. Smith and A. Alcami (2002)
J. Virol. 76, 1124-1134
 |  Abstract »  |  Full Text »  |  PDF »

Human Parainfluenza Virus Type 3 Inhibits Gamma Interferon-Induced Major Histocompatibility Complex Class II Expression Directly and by Inducing Alpha/Beta Interferon.

J. Gao, B. P. De, Y. Han, S. Choudhary, R. Ransohoff, and A. K. Banerjee (2001)
J. Virol. 75, 1124-1131
 |  Abstract »  |  Full Text »

Both Carboxy- and Amino-Terminal Domains of the Vaccinia Virus Interferon Resistance Gene, E3L, Are Required for Pathogenesis in a Mouse Model.

T. A. Brandt and B. L. Jacobs (2001)
J. Virol. 75, 850-856
 |  Abstract »  |  Full Text »

Vaccinia Virus Vectors with an Inactivated Gamma Interferon Receptor Homolog Gene (B8R) Are Attenuated In Vivo without a Concomitant Reduction in Immunogenicity.

P. H. Verardi, L. A. Jones, F. H. Aziz, S. Ahmad, and T. D. Yilma (2001)
J. Virol. 75, 11-18
 |  Abstract »  |  Full Text »

Interferons: cell signalling, immune modulation, antiviral response and virus countermeasures.

S. Goodbourn, L. Didcock, and R. E. Randall (2000)
J. Gen. Virol. 81, 2341-2364
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Poxvirus-Induced Immunostimulating Effects on Porcine Leukocytes.

V. Fachinger, T. Schlapp, W. Strube, N. Schmeer, and A. Saalmüller (2000)
J. Virol. 74, 7943-7951
 |  Abstract »  |  Full Text »

Identification of a Gammaherpesvirus Selective Chemokine Binding Protein That Inhibits Chemokine Action.

V. van Berkel, J. Barrett, H. L. Tiffany, D. H. Fremont, P. M. Murphy, G. McFadden, S. H. Speck, and H. W. Virgin IV (2000)
J. Virol. 74, 6741-6747
 |  Abstract »  |  Full Text »

Conserved Surface-Exposed K/R-X-K/R Motifs and Net Positive Charge on Poxvirus Complement Control Proteins Serve as Putative Heparin Binding Sites and Contribute to Inhibition of Molecular Interactions with Human Endothelial Cells: a Novel Mechanism for Evasion of Host Defense.

S. A. Smith, N. P. Mullin, J. Parkinson, S. N. Shchelkunov, A. V. Totmenin, V. N. Loparev, R. Srisatjaluk, D. N. Reynolds, K. L. Keeling, D. E. Justus, et al. (2000)
J. Virol. 74, 5659-5666
 |  Abstract »  |  Full Text »

Ectromelia virus virulence factor p28 acts upstream of caspase-3 in response to UV light-induced apoptosis.

D. J. Brick, R. D. Burke, A. A. Minkley, and C. Upton (2000)
J. Gen. Virol. 81, 1087-1097
 |  Abstract »  |  Full Text »

A Poxvirus Protein That Binds to and Inactivates IL-18, and Inhibits NK Cell Response.

T. L. Born, L. A. Morrison, D. J. Esteban, T. VandenBos, L. G. Thebeau, N. Chen, M. K. Spriggs, J. E. Sims, and R. M. L. Buller (2000)
J. Immunol. 164, 3246-3254
 |  Abstract »  |  Full Text »  |  PDF »

KSHV-encoded CC chemokine vMIP-III is a CCR4 agonist, stimulates angiogenesis, and selectively chemoattracts TH2 cells.

J. T. Stine, C. Wood, M. Hill, A. Epp, C. J. Raport, V. L. Schweickart, Y. Endo, T. Sasaki, G. Simmons, C. Boshoff, et al. (2000)
Blood 95, 1151-1157
 |  Abstract »  |  Full Text »  |  PDF »

The V Protein of Simian Virus 5 Inhibits Interferon Signalling by Targeting STAT1 for Proteasome-Mediated Degradation.

L. Didcock, D. F. Young, S. Goodbourn, and R. E. Randall (1999)
J. Virol. 73, 9928-9933
 |  Abstract »  |  Full Text »

IL-18 binding and inhibition of interferon gamma induction by human poxvirus-encoded proteins.

Y. Xiang and B. Moss (1999)
PNAS 96, 11537-11542
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of immune escape in viral hepatitis.

W ROSENBERG (1999)
Gut 44, 759-764
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Serp2, an Inhibitor of the Interleukin-1beta -Converting Enzyme, Is Critical in the Pathobiology of Myxoma Virus.

F. Messud-Petit, J. Gelfi, M. Delverdier, M.-F. Amardeilh, R. Py, G. Sutter, and S. Bertagnoli (1998)
J. Virol. 72, 7830-7839
 |  Abstract »  |  Full Text »  |  PDF »

Functional Analysis of the Human Cytomegalovirus US28 Gene by Insertion Mutagenesis with the Green Fluorescent Protein Gene.

J. Vieira, T. J. Schall, L. Corey, and A. P. Geballe (1998)
J. Virol. 72, 8158-8165
 |  Abstract »  |  Full Text »  |  PDF »

Virus Attenuation after Deletion of the Cytomegalovirus Fc Receptor Gene Is Not due to Antibody Control.

I. Crnkovic-Mertens, M. Messerle, U. Szepan, and U. H. Koszinowski (1998)
J. Virol. 72, 1377-1382
 |  Abstract »  |  Full Text »  |  PDF »

Blockade of Chemokine Activity by a Soluble Chemokine Binding Protein from Vaccinia Virus.

A. Alcami, J. A. Symons, P. D. Collins, T. J. Williams, and G. L. Smith (1998)
J. Immunol. 160, 624-633
 |  Abstract »  |  Full Text »  |  PDF »

Myxoma Virus T2 Protein, a Tumor Necrosis Factor (TNF) Receptor Homolog, Is Secreted as a Monomer and Dimer That Each Bind Rabbit TNFalpha , but the Dimer Is a More Potent TNF Inhibitor.

M. Schreiber, K. Rajarathnam, and G. McFadden (1996)
J. Biol. Chem. 271, 13333-13341
 |  Abstract »  |  Full Text »  |  PDF »

Cytokines and viral anti-immune genes.

C. Evans (1996)
Stem Cells 14, 177-184
 |  Abstract »

Vaccinia Virus B18R Gene Encodes a Type I Interferon-binding Protein That Blocks Interferon [IMAGE] Transmembrane Signaling.

O. R. Colamonici, P. Domanski, S. M. Sweitzer, A. Larner, and R. M. L. Buller (1995)
J. Biol. Chem. 270, 15974-15978
 |  Abstract »  |  Full Text »  |  PDF »

The Myxoma Virus-soluble Interferon-[IMAGE] Receptor Homolog, M-T7, Inhibits Interferon-[IMAGE] in a Species-specific Manner.

K. Mossman, C. Upton, and G. McFadden (1995)
J. Biol. Chem. 270, 3031-3038
 |  Abstract »  |  Full Text »  |  PDF »

Viral Imitations of Host Defense Proteins: Flattery That Turns to Battery.

P. M. Murphy (1994)
JAMA 271, 1948-1952
 |  Abstract »  |  PDF »

Why the smallpox virus stocks should not be destroyed.

W. Joklik, B Moss, B. Fields, D. Bishop, and L. Sandakhchiev (1993)
Science 262, 1225-1226
 |  PDF »

Viruses launch their own 'star wars'.

M Barinaga (1992)
Science 258, 1730-1731
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Glycosaminoglycan Binding Properties of the Myxoma Virus CC-chemokine Inhibitor, M-T1.

B. T. Seet, J. Barrett, J. Robichaud, B. Shilton, R. Singh, and G. McFadden (2001)
J. Biol. Chem. 276, 30504-30513
 |  Abstract »  |  Full Text »  |  PDF »

A soluble class II cytokine receptor, IL-22RA2, is a naturally occurring IL-22 antagonist.

W. Xu, S. R. Presnell, J. Parrish-Novak, W. Kindsvogel, S. Jaspers, Z. Chen, S. R. Dillon, Z. Gao, T. Gilbert, K. Madden, et al. (2001)
PNAS 98, 9511-9516
 |  Abstract »  |  Full Text »  |  PDF »

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