Science 6 November 1992: Vol. 258. no. 5084, pp. 987 - 991 DOI: 10.1126/science.1279805

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Articles

The Crystal Structure of Pectate Lyase PelI from Soft Rot Pathogen Erwinia chrysanthemi in Complex with Its Substrate.

C. Creze, S. Castang, E. Derivery, R. Haser, N. Hugouvieux-Cotte-Pattat, V. E. Shevchik, and P. Gouet (2008)
J. Biol. Chem. 283, 18260-18268
 |  Abstract »  |  Full Text »  |  PDF »

High-resolution design of a protein loop.

X. Hu, H. Wang, H. Ke, and B. Kuhlman (2007)
PNAS 104, 17668-17673
 |  Abstract »  |  Full Text »  |  PDF »

Designing an extracellular matrix protein with enhanced mechanical stability.

S. P. Ng, K. S. Billings, T. Ohashi, M. D. Allen, R. B. Best, L. G. Randles, H. P. Erickson, and J. Clarke (2007)
PNAS 104, 9633-9637
 |  Abstract »  |  Full Text »  |  PDF »

Molecular determinants for the recruitment of the ubiquitin-ligase MuRF-1 onto M-line titin.

M. Mrosek, D. Labeit, S. Witt, H. Heerklotz, E. von Castelmur, S. Labeit, and O. Mayans (2007)
FASEB J 21, 1383-1392
 |  Abstract »  |  Full Text »  |  PDF »

Identification of the Heparin-binding Determinants within Fibronectin Repeat III1: ROLE IN CELL SPREADING AND GROWTH.

L. Gui, K. Wojciechowski, C. D. Gildner, H. Nedelkovska, and D. C. Hocking (2006)
J. Biol. Chem. 281, 34816-34825
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From the Cover: Structure of a heparin-dependent complex of Hedgehog and Ihog.

J. S. McLellan, S. Yao, X. Zheng, B. V. Geisbrecht, R. Ghirlando, P. A. Beachy, and D. J. Leahy (2006)
PNAS 103, 17208-17213
 |  Abstract »  |  Full Text »  |  PDF »

Using Model Proteins to Quantify the Effects of Pathogenic Mutations in Ig-like Proteins.

L. G. Randles, I. Lappalainen, S. B. Fowler, B. Moore, S. J. Hamill, and J. Clarke (2006)
J. Biol. Chem. 281, 24216-24226
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Gene Expression Changes during the Development of Acute Lung Injury Role of Transforming Growth Factor {beta}.

S. C. Wesselkamper, L. M. Case, L. N. Henning, M. T. Borchers, J. W. Tichelaar, J. M. Mason, N. Dragin, M. Medvedovic, M. A. Sartor, C. R. Tomlinson, et al. (2005)
Am. J. Respir. Crit. Care Med. 172, 1399-1411
 |  Abstract »  |  Full Text »  |  PDF »

Domain Unfolding Plays a Role in Superfibronectin Formation.

T. Ohashi and H. P. Erickson (2005)
J. Biol. Chem. 280, 39143-39151
 |  Abstract »  |  Full Text »  |  PDF »

Structure of Ptr ToxA: An RGD-Containing Host-Selective Toxin from Pyrenophora tritici-repentis.

G. N. Sarma, V. A. Manning, L. M. Ciuffetti, and P. A. Karplus (2005)
PLANT CELL 17, 3190-3202
 |  Abstract »  |  Full Text »  |  PDF »

Specific Amino Acids in the First Fibronectin Type III Repeat of the Neural Cell Adhesion Molecule Play a Role in Its Recognition and Polysialylation by the Polysialyltransferase ST8Sia IV/PST.

S. S. Mendiratta, N. Sekulic, A. Lavie, and K. J. Colley (2005)
J. Biol. Chem. 280, 32340-32348
 |  Abstract »  |  Full Text »  |  PDF »

Crystal Structure of the "PhoU-Like" Phosphate Uptake Regulator from Aquifex aeolicus.

V. Oganesyan, N. Oganesyan, P. D. Adams, J. Jancarik, H. A. Yokota, R. Kim, and S.-H. Kim (2005)
J. Bacteriol. 187, 4238-4244
 |  Abstract »  |  Full Text »  |  PDF »

Crystal Structure of a Nicotinate Phosphoribosyltransferase from Thermoplasma acidophilum.

D. H. Shin, N. Oganesyan, J. Jancarik, H. Yokota, R. Kim, and S.-H. Kim (2005)
J. Biol. Chem. 280, 18326-18335
 |  Abstract »  |  Full Text »  |  PDF »

Ribosomal protein L1 recognizes the same specific structural motif in its target sites on the autoregulatory mRNA and 23S rRNA.

N. Nevskaya, S. Tishchenko, A. Gabdoulkhakov, E. Nikonova, O. Nikonov, A. Nikulin, O. Platonova, M. Garber, S. Nikonov, and W. Piendl (2005)
Nucleic Acids Res. 33, 478-485
 |  Abstract »  |  Full Text »  |  PDF »

Crystal structure of YjeQ from Thermotoga maritima contains a circularly permuted GTPase domain.

D. H. Shin, Y. Lou, J. Jancarik, H. Yokota, R. Kim, and S.-H. Kim (2004)
PNAS 101, 13198-13203
 |  Abstract »  |  Full Text »  |  PDF »

Crystal structure of pyrogallol-phloroglucinol transhydroxylase, an Mo enzyme capable of intermolecular hydroxyl transfer between phenols.

A. Messerschmidt, H. Niessen, D. Abt, O. Einsle, B. Schink, and P. M. H. Kroneck (2004)
PNAS 101, 11571-11576
 |  Abstract »  |  Full Text »  |  PDF »

Identification and Kinetics Analysis of a Novel Heparin-binding Site (KEDK) in Human Tenascin-C.

J.-H. Jang, J.-H. Hwang, C.-P. Chung, and P.-H. Choung (2004)
J. Biol. Chem. 279, 25562-25566
 |  Abstract »  |  Full Text »  |  PDF »

Mechanism of homophilic adhesion by the neural cell adhesion molecule: Use of multiple domains and flexibility.

C. P. Johnson, I. Fujimoto, C. Perrin-Tricaud, U. Rutishauser, and D. Leckband (2004)
PNAS 101, 6963-6968
 |  Abstract »  |  Full Text »  |  PDF »

Neurite Outgrowth by the Alternatively Spliced Region of Human Tenascin-C Is Mediated by Neuronal {alpha}7{beta}1 Integrin.

M. L. T. Mercado, A. Nur-e-Kamal, H.-Y. Liu, S. R. Gross, R. Movahed, and S. Meiners (2004)
J. Neurosci. 24, 238-247
 |  Abstract »  |  Full Text »  |  PDF »

A tenascin-C aptamer identified by tumor cell SELEX: Systematic evolution of ligands by exponential enrichment.

D. A. Daniels, H. Chen, B. J. Hicke, K. M. Swiderek, and L. Gold (2003)
PNAS 100, 15416-15421
 |  Abstract »  |  Full Text »  |  PDF »

Self-consistent determination of the transition state for protein folding: Application to a fibronectin type III domain.

E. Paci, J. Clarke, A. Steward, M. Vendruscolo, and M. Karplus (2003)
PNAS 100, 394-399
 |  Abstract »  |  Full Text »  |  PDF »

Use of phage display to probe the evolution of binding specificity and affinity in integrins.

R. Li, R. H. Hoess, J. S. Bennett, and W. F. DeGrado (2003)
Protein Eng. Des. Sel. 16, 65-72
 |  Abstract »  |  Full Text »  |  PDF »

Structure of the extracellular domains of the human interleukin-6 receptor alpha -chain.

J. N. Varghese, R. L. Moritz, M.-Z. Lou, A. van Donkelaar, H. Ji, N. Ivancic, K. M. Branson, N. E. Hall, and R. J. Simpson (2002)
PNAS 99, 15959-15964
 |  Abstract »  |  Full Text »  |  PDF »

Key interactions in neocarzinostatin, a protein of the immunoglobulin fold family.

M. Valerio-Lepiniec, M. Nicaise, E. Adjadj, P. Minard, and M. Desmadril (2002)
Protein Eng. Des. Sel. 15, 861-869
 |  Abstract »  |  Full Text »  |  PDF »

The Fibronectin Type 3-Like Repeat from the Clostridium thermocellum Cellobiohydrolase CbhA Promotes Hydrolysis of Cellulose by Modifying Its Surface.

I. A. Kataeva, R. D. Seidel III, A. Shah, L. T. West, X.-L. Li, and L. G. Ljungdahl (2002)
Appl. Envir. Microbiol. 68, 4292-4300
 |  Abstract »  |  Full Text »  |  PDF »

Crystal structure of conserved hypothetical protein Aq1575 from Aquifexaeolicus.

D. H. Shin, H. Yokota, R. Kim, and S.-H. Kim (2002)
PNAS 99, 7980-7985
 |  Abstract »  |  Full Text »  |  PDF »

Supramolecular Chemistry And Self-assembly Special Feature: Fibronectin extension and unfolding within cell matrix fibrils controlled by cytoskeletal tension.

G. Baneyx, L. Baugh, and V. Vogel (2002)
PNAS 99, 5139-5143
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Neurite Outgrowth-Promoting Motif within the Alternatively Spliced Region of Human Tenascin-C.

S. Meiners, M. S.A. Nur-e-Kamal, and M. L. T. Mercado (2001)
J. Neurosci. 21, 7215-7225
 |  Abstract »  |  Full Text »  |  PDF »

Blockade of {{alpha}}5{{beta}}1 Integrins Reverses the Inhibitory Effect of Tenascin on Chemotaxis of Human Monocytes and Polymorphonuclear Leukocytes Through Three-Dimensional Gels of Extracellular Matrix Proteins.

J. D. Loike, L. Cao, S. Budhu, S. Hoffman, and S. C. Silverstein (2001)
J. Immunol. 166, 7534-7542
 |  Abstract »  |  Full Text »  |  PDF »

Alpha-fetoprotein Structure and Function: Relevance to Isoforms, Epitopes, and Conformational Variants.

G. J. Mizejewski (2001)
Experimental Biology and Medicine 226, 377-408
 |  Abstract »  |  Full Text »

Nedd8 Modification of Cul-1 Activates SCFbeta TrCP-Dependent Ubiquitination of Ikappa Balpha.

M. A. Read, J. E. Brownell, T. B. Gladysheva, M. Hottelet, L. A. Parent, M. B. Coggins, J. W. Pierce, V. N. Podust, R.-S. Luo, V. Chau, et al. (2000)
Mol. Cell. Biol. 20, 2326-2333
 |  Abstract »  |  Full Text »

A novel RGD-independent fibronectin assembly pathway initiated by alpha4beta1 integrin binding to the alternatively spliced V region.

J. Sechler, A. Cumiskey, D. Gazzola, and J. Schwarzbauer (2000)
J. Cell Sci. 113, 1491-1498
 |  Abstract »  |  PDF »

Domain organization of the extracellular region of CD45.

A. Symons, A. C. Willis, and A.N. Barclay (1999)
Protein Eng. Des. Sel. 12, 885-892
 |  Abstract »  |  Full Text »  |  PDF »

Structure of Adenovirus Complexed with Its Internalization Receptor, alpha vbeta 5 Integrin.

C. Y. Chiu, P. Mathias, G. R. Nemerow, and P. L. Stewart (1999)
J. Virol. 73, 6759-6768
 |  Abstract »  |  Full Text »

Identification of Two Amino Acids within the EIIIA (ED-A) Segment of Fibronectin Constituting the Epitope for Two Function-blocking Monoclonal Antibodies.

Y.-F. Liao, K. G. Wieder, J. M. Classen, and L. V. De Water (1999)
J. Biol. Chem. 274, 17876-17884
 |  Abstract »  |  Full Text »  |  PDF »

Crystal Structure of a Conserved Ribosomal Protein-RNA Complex.

G. L. Conn, D. E. Draper, E. E. Lattman, and A. G. Gittis (1999)
Science 284, 1171-1174
 |  Abstract »  |  Full Text »

The Cation-binding Domain from the alpha  Subunit of Integrin alpha 5beta 1 Is a Minimal Domain for Fibronectin Recognition.

J.-L. Baneres, F. Roquet, M. Green, H. LeCalvez, and J. Parello (1998)
J. Biol. Chem. 273, 24744-24753
 |  Abstract »  |  Full Text »  |  PDF »

Proliferating and Migrating Mesangial Cells Responding to Injury Express a Novel Receptor Protein-tyrosine Phosphatase in Experimental Mesangial Proliferative Glomerulonephritis.

M. B. Wright, C. Hugo, R. Seifert, C. M. Disteche, and D. F. Bowen-Pope (1998)
J. Biol. Chem. 273, 23929-23937
 |  Abstract »  |  Full Text »  |  PDF »

Identification of the Ligand Binding Site for the Integrin alpha 9beta 1 in the Third Fibronectin Type III Repeat of Tenascin-C.

Y. Yokosaki, N. Matsuura, S. Higashiyama, I. Murakami, M. Obara, M. Yamakido, N. Shigeto, J. Chen, and D. Sheppard (1998)
J. Biol. Chem. 273, 11423-11428
 |  Abstract »  |  Full Text »  |  PDF »

Crystal structure of MTCP-1: Implications for role of TCL-1 and MTCP-1 in T cell malignancies.

Z.-Q. Fu, G. C. Du Bois, S. P. Song, I. Kulikovskaya, L. Virgilio, J. L. Rothstein, C. M. Croce, I. T. Weber, and R. W. Harrison (1998)
PNAS 95, 3413-3418
 |  Abstract »  |  Full Text »  |  PDF »

Organization of the Neurofascin Gene and Analysis of Developmentally Regulated Alternative Splicing.

B. Hassel, F. G. Rathjen, and H. Volkmer (1997)
J. Biol. Chem. 272, 28742-28749
 |  Abstract »  |  Full Text »  |  PDF »

Cryptic Self-association Sites in Type III Modules of Fibronectin.

K. C. Ingham, S. A. Brew, S. Huff, and S. V. Litvinovich (1997)
J. Biol. Chem. 272, 1718-1724
 |  Abstract »  |  Full Text »  |  PDF »

Concerted action of tenascin-C domains in cell adhesion, anti-adhesion and promotion of neurite outgrowth.

D Fischer, M Brown-Ludi, T Schulthess, and R Chiquet-Ehrismann (1997)
J. Cell Sci. 110, 1513-1522
 |  Abstract »  |  PDF »

Cloning and Characterization of Rat Density-Enhanced Phosphatase-1, a Protein Tyrosine Phosphatase Expressed by Vascular Cells.

L. G. Borges, R. A. Seifert, F. J. Grant, C. E. Hart, C. M. Disteche, S. Edelhoff, F. F. Solca, M. A. Lieberman, V. Lindner, E. H. Fischer, et al. (1996)
Circ. Res. 79, 570-580
 |  Abstract »  |  Full Text »

Systematic Replacement of Amino Acid Residues within an Arg-Gly-Asp-containing Loop of Foot-and-Mouth Disease Virus and Effect on Cell Recognition.

M. G. Mateu, M. L. Valero, D. Andreu, and E. Domingo (1996)
J. Biol. Chem. 271, 12814-12819
 |  Abstract »  |  Full Text »  |  PDF »

The Amino-terminal One-third of alpha[IMAGE] Defines the Ligand Recognition Specificity of Integrin alpha[IMAGE]beta(3).

J. C. Loftus, C. E. Halloran, M. H. Ginsberg, L. P. Feigen, J. A. Zablocki, and J. W. Smith (1996)
J. Biol. Chem. 271, 2033-2039
 |  Abstract »  |  Full Text »  |  PDF »

Heparin Binding by Fibronectin Module III-13 Involves Six Discontinuous Basic Residues Brought Together to Form a Cationic Cradle.

T. F. Busby, W. S. Argraves, S. A. Brew, I. Pechik, G. L. Gilliland, and K. C. Ingham (1995)
J. Biol. Chem. 270, 18558-18562
 |  Abstract »  |  Full Text »  |  PDF »

Protein Determinants for Specific Polysialylation of the Neural Cell Adhesion Molecule.

R. W. Nelson, P. A. Bates, and U. Rutishauser (1995)
J. Biol. Chem. 270, 17171-17179
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-6 (IL-6) Antagonism by Soluble IL-6 Receptor [IMAGE] Mutated in the Predicted gp130-binding Interface.

A. L. Salvati, A. Lahm, G. Paonessa, G. Ciliberto, and C. Toniatti (1995)
J. Biol. Chem. 270, 12242-12249
 |  Abstract »  |  Full Text »  |  PDF »

Structure of a Conformationally Constrained Arg-Gly-Asp Sequence Inserted into Human Lysozyme.

T. Yamada, H. Song, K. Inaka, Y. Shimada, M. Kikuchi, and M. Matsushima (1995)
J. Biol. Chem. 270, 5687-5690
 |  Abstract »  |  Full Text »  |  PDF »

Tenascin-C Binds Heparin by Its Fibronectin Type III Domain Five.

P. Weber, D. R. Zimmermann, K. H. Winterhalter, and L. Vaughan (1995)
J. Biol. Chem. 270, 4619-4623
 |  Abstract »  |  Full Text »  |  PDF »

A Single Heparin Binding Region within the Fibrinogen-like Domain Is Functional in Chick Tenascin-C.

D. Fischer, R. Chiquet-Ehrismann, C. Bernasconi, and M. Chiquet (1995)
J. Biol. Chem. 270, 3378-3384
 |  Abstract »  |  Full Text »  |  PDF »

Crystal Structure of the OPG2 Fab.

R. Kodandapani, B. Veerapandian, T. J. Kunicki, and K. R. Ely (1995)
J. Biol. Chem. 270, 2268-2273
 |  Abstract »  |  Full Text »  |  PDF »

Structure of the RGD protein decorsin: conserved motif and distinct function in leech proteins that affect blood clotting.

A. Krezel, G Wagner, J Seymour-Ulmer, and R. Lazarus (1994)
Science 264, 1944-1947
 |  Abstract »  |  PDF »

Structure of the allosteric regulatory enzyme of purine biosynthesis.

J. Smith, E. Zaluzec, J. Wery, L Niu, R. Switzer, H Zalkin, and Y Satow (1994)
Science 264, 1427-1433
 |  Abstract »  |  PDF »

Identification of a key integrin-binding sequence in VCAM-1 homologous to the LDV active site in fibronectin.

J. Clements, P Newham, M Shepherd, R Gilbert, T. Dudgeon, L. Needham, R. Edwards, L Berry, A Brass, and M. Humphries (1994)
J. Cell Sci. 107, 2127-2135
 |  Abstract »  |  PDF »

Crystal structure of neocarzinostatin, an antitumor protein-chromophore complex.

K. Kim, B. Kwon, A. Myers, and D. Rees (1993)
Science 262, 1042-1046
 |  Abstract »  |  PDF »

Endothelial cells adhere to the RGD domain and the fibrinogen-like terminal knob of tenascin.

P Joshi, C. Chung, I Aukhil, and H. Erickson (1993)
J. Cell Sci. 106, 389-400
 |  Abstract »  |  PDF »

Identification and Characterization of a Conformational Heparin-binding Site Involving Two Fibronectin Type III Modules of Bovine Tenascin-X.

C. Lethias, F. Elefteriou, G. Parsiegla, J.-Y. Exposito, and R. Garrone (2001)
J. Biol. Chem. 276, 16432-16438
 |  Abstract »  |  Full Text »  |  PDF »

Crystal Structure and Biophysical Properties of a Complex between the N-terminal SNARE Region of SNAP25 and Syntaxin 1a.

K. M. S. Misura, L. C. Gonzalez Jr., A. P. May, R. H. Scheller, and W. I. Weis (2001)
J. Biol. Chem. 276, 41301-41309
 |  Abstract »  |  Full Text »  |  PDF »

Unfolding proteins by external forces and temperature: The importance of topology and energetics.

E. Paci and M. Karplus (2000)
PNAS 97, 6521-6526
 |  Abstract »  |  Full Text »  |  PDF »

Crystal structure of an intracellular protease from Pyrococcus horikoshii at 2-A resolution.

X. Du, I.-G. Choi, R. Kim, W. Wang, J. Jancarik, H. Yokota, and S.-H. Kim (2000)
PNAS 97, 14079-14084
 |  Abstract »  |  Full Text »  |  PDF »

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