Science 23 October 1992: Vol. 258. no. 5082, pp. 607 - 614 DOI: 10.1126/science.1411571

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Articles

PKC{zeta}-mediated phosphorylation controls budding of the pre-chylomicron transport vesicle.

S. A. Siddiqi and C. M. Mansbach II (2008)
J. Cell Sci. 121, 2327-2338
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Phosphorylation of AFAP-110 affects podosome lifespan in A7r5 cells.

A. Dorfleutner, Y. Cho, D. Vincent, J. Cunnick, H. Lin, S. A. Weed, C. Stehlik, and D. C. Flynn (2008)
J. Cell Sci. 121, 2394-2405
 |  Abstract »  |  Full Text »  |  PDF »

Enzymological Analysis of Mutant Protein Kinase C{gamma} Causing Spinocerebellar Ataxia Type 14 and Dysfunction in Ca2+ Homeostasis.

N. Adachi, T. Kobayashi, H. Takahashi, T. Kawasaki, Y. Shirai, T. Ueyama, T. Matsuda, T. Seki, N. Sakai, and N. Saito (2008)
J. Biol. Chem. 283, 19854-19863
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AMP-activated Protein Kinase Phosphorylates and Desensitizes Smooth Muscle Myosin Light Chain Kinase.

S. Horman, N. Morel, D. Vertommen, N. Hussain, D. Neumann, C. Beauloye, N. E. Najjar, C. Forcet, B. Viollet, M. P. Walsh, et al. (2008)
J. Biol. Chem. 283, 18505-18512
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Thematic Review Series: Glycerolipids. Phosphatidylserine and phosphatidylethanolamine in mammalian cells: two metabolically related aminophospholipids.

J. E. Vance (2008)
J. Lipid Res. 49, 1377-1387
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Saccharomyces cerevisiae Phospholipase C Regulates Transcription of Msn2p-Dependent Stress-Responsive Genes.

A. Demczuk, N. Guha, P. H. Nguyen, P. Desai, J. Chang, K. Guzinska, J. Rollins, C. C. Ghosh, L. Goodwin, and A. Vancura (2008)
Eukaryot. Cell 7, 967-979
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Characteristics of KIT-negative gastrointestinal stromal tumours and diagnostic utility of protein kinase C theta immunostaining.

H E Lee, M A Kim, H S Lee, B L Lee, and W H Kim (2008)
J. Clin. Pathol. 61, 722-729
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A Direct Redox Regulation of Protein Kinase C Isoenzymes Mediates Oxidant-induced Neuritogenesis in PC12 Cells.

R. Gopalakrishna, U. Gundimeda, J. E. Schiffman, and T. H. McNeill (2008)
J. Biol. Chem. 283, 14430-14444
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TGF-{beta} mediates PTEN suppression and cell motility through calcium-dependent PKC-{alpha} activation in pancreatic cancer cells.

J. Y. C. Chow, H. Dong, K. T. Quach, P. N. Van Nguyen, K. Chen, and J. M. Carethers (2008)
Am J Physiol Gastrointest Liver Physiol 294, G899-G905
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Immunogold Electron Microscopic Demonstration of Distinct Submembranous Localization of the Activated {gamma}PKC Depending on the Stimulation.

M. Oyasu, M. Fujimiya, K. Kashiwagi, S. Ohmori, H. Imaeda, and N. Saito (2008)
J. Histochem. Cytochem. 56, 253-265
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Protein kinase C{delta} regulates endothelial nitric oxide synthase expression via Akt activation and nitric oxide generation.

N. Sud, S. Wedgwood, and S. M. Black (2008)
Am J Physiol Lung Cell Mol Physiol 294, L582-L591
 |  Abstract »  |  Full Text »  |  PDF »

Bistable MAP kinase activity: a plausible mechanism contributing to maintenance of late long-term potentiation.

P. Smolen, D. A. Baxter, and J. H. Byrne (2008)
Am J Physiol Cell Physiol 294, C503-C515
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Eucapnic intermittent hypoxia augments endothelin-1 vasoconstriction in rats: role of PKC{delta}.

K. J. Allahdadi, L. C. Duling, B. R. Walker, and N. L. Kanagy (2008)
Am J Physiol Heart Circ Physiol 294, H920-H927
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Opposite Effect of Phorbol Ester PMA on PTGS2 and PGDH mRNA Expression in Human Chorion Trophoblast Cells.

V. Casciani, E. Marinoni, A. D. Bocking, M. Moscarini, R. Di Iorio, and J. R. G. Challis (2008)
Reproductive Sciences 15, 40-50
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Inhibition of protein kinase C{alpha} improves myocardial -adrenergic receptor signaling and ventricular function in a model of myocardial preservation.

K. M. D'Souza, N. N. Petrashevskaya, W. H. Merrill, and S. A. Akhter (2008)
J. Thorac. Cardiovasc. Surg. 135, 172-179
 |  Abstract »  |  Full Text »  |  PDF »

Role of Protein Kinase C Isozymes in the Regulation of alpha1-Adrenergic Receptor-Mediated Contractions in Ovine Uterine Arteries.

H. Zhang and L. Zhang (2008)
Biol Reprod 78, 35-42
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Subtype Activation and Interaction of Protein Kinase C and Mitogen-Activated Protein Kinase Controlling Receptor Expression in Cerebral Arteries and Microvessels After Subarachnoid Hemorrhage.

S. Ansar and L. Edvinsson (2008)
Stroke 39, 185-190
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A Critical Role of Protein Kinase C{delta} Activation Loop Phosphorylation in Formyl-Methionyl-Leucyl-Phenylalanine-Induced Phosphorylation of p47phox and Rapid Activation of Nicotinamide Adenine Dinucleotide Phosphate Oxidase.

N. Cheng, R. He, J. Tian, M. C. Dinauer, and R. D. Ye (2007)
J. Immunol. 179, 7720-7728
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase C{delta} Regulates Airway Mucin Secretion via Phosphorylation of MARCKS Protein.

J.-A. Park, A. L. Crews, W. R. Lampe, S. Fang, J. Park, and K. B. Adler (2007)
Am. J. Pathol. 171, 1822-1830
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Respiratory: Protein kinase C activity in the nucleus tractus solitarii is critically involved in the acute hypoxic ventilatory response, but is not required for intermittent hypoxia-induced phrenic long-term facilitation in adult rats.

S. R. Reeves and D. Gozal (2007)
Exp Physiol 92, 1057-1066
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Acidic Amino Acid Residues in the Protein Kinase C{alpha} V5 Domain That Contribute to Its Insensitivity to Diacylglycerol.

H. Stensman and C. Larsson (2007)
J. Biol. Chem. 282, 28627-28638
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{alpha}- and {epsilon}-Protein Kinase C Activity during Smooth Muscle Cell Apoptosis in Response to {gamma}-Radiation.

S. Claro, C. A. Kanashiro, M. E. M. Oshiro, A. T. Ferreira, and R. A. Khalil (2007)
J. Pharmacol. Exp. Ther. 322, 964-972
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Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral Protein Kinase C {beta}-Inhibitor Enzastaurin in Combination with Gemcitabine and Cisplatin in Patients with Advanced Cancer.

J. M. Rademaker-Lakhai, L. V. Beerepoot, N. Mehra, S. A. Radema, R. van Maanen, J. S. Vermaat, E. O. Witteveen, C. M. Visseren-Grul, L. Musib, N. Enas, et al. (2007)
Clin. Cancer Res. 13, 4474-4481
 |  Abstract »  |  Full Text »  |  PDF »

Mechanism of Inhibition of Sequestration of Protein Kinase C {alpha}/betaII by Ceramide: ROLES OF CERAMIDE-ACTIVATED PROTEIN PHOSPHATASES AND PHOSPHORYLATION/DEPHOSPHORYLATION OF PROTEIN KINASE C {alpha}/betaII ON THREONINE 638/641.

K. Kitatani, J. Idkowiak-Baldys, and Y. A. Hannun (2007)
J. Biol. Chem. 282, 20647-20656
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Phosphorylation of Pleckstrin Increases Proinflammatory Cytokine Secretion by Mononuclear Phagocytes in Diabetes Mellitus.

Y. Ding, A. Kantarci, J. A. Badwey, H. Hasturk, A. Malabanan, and T. E. Van Dyke (2007)
J. Immunol. 179, 647-654
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Dietary Polyunsaturated Fatty Acids Alter Myocardial Protein Kinase C Expression and Affect Cardioprotection Induced by Chronic Hypoxia.

M. Hlavackova, J. Neckar, J. Jezkova, P. Balkova, B. Stankova, O. Novakova, F. Kolar, and F. Novak (2007)
Experimental Biology and Medicine 232, 823-832
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Another Mutation in Cysteine 131 in Protein Kinase C{gamma} as a Cause of Spinocerebellar Ataxia Type 14.

S. Klebe, L. Faivre, S. Forlani, C. Dussert, A. Tourbah, A. Brice, G. Stevanin, and A. Durr (2007)
Arch Neurol 64, 913-914
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Protein kinase C delta stimulates antigen presentation by Class II MHC in murine dendritic cells.

M. Majewski, T. O. Bose, F. C. M. Sille, A. M. Pollington, E. Fiebiger, and M. Boes (2007)
Int. Immunol. 19, 719-732
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n-3 Fatty Acids Preserve Insulin Sensitivity In Vivo in a Peroxisome Proliferator-Activated Receptor-{alpha}-Dependent Manner.

S. Neschen, K. Morino, J. Dong, Y. Wang-Fischer, G. W. Cline, A. J. Romanelli, J. C. Rossbacher, I. K. Moore, W. Regittnig, D. S. Munoz, et al. (2007)
Diabetes 56, 1034-1041
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G{alpha}q-TRPC6-mediated Ca2+ Entry Induces RhoA Activation and Resultant Endothelial Cell Shape Change in Response to Thrombin.

I. Singh, N. Knezevic, G. U. Ahmmed, V. Kini, A. B. Malik, and D. Mehta (2007)
J. Biol. Chem. 282, 7833-7843
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Skeletal muscle lipid deposition and insulin resistance: effect of dietary fatty acids and exercise.

M. P Corcoran, S. Lamon-Fava, and R. A Fielding (2007)
Am. J. Clinical Nutrition 85, 662-677
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N-acetylcysteine attenuates PKC{beta}2 overexpression and myocardial hypertrophy in streptozotocin-induced diabetic rats.

Z. Xia, K.-H. Kuo, P. R. Nagareddy, F. Wang, Z. Guo, T. Guo, J. Jiang, and J. H. McNeill (2007)
Cardiovasc Res 73, 770-782
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Lack of osteopontin improves cardiac function in streptozotocin-induced diabetic mice.

V. Subramanian, P. Krishnamurthy, K. Singh, and M. Singh (2007)
Am J Physiol Heart Circ Physiol 292, H673-H683
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Coadministration of Sorafenib with Rottlerin Potently Inhibits Cell Proliferation and Migration in Human Malignant Glioma Cells.

E. P. Jane, D. R. Premkumar, and I. F. Pollack (2006)
J. Pharmacol. Exp. Ther. 319, 1070-1080
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Transcriptional and posttranscriptional regulation of endothelial nitric oxide synthase expression.

C. D. Searles (2006)
Am J Physiol Cell Physiol 291, C803-C816
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Regulation of {alpha}1-adrenoceptor-mediated contractions of uterine arteries by PKC: effect of pregnancy.

H. Zhang, D. Xiao, L. D. Longo, and L. Zhang (2006)
Am J Physiol Heart Circ Physiol 291, H2282-H2289
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Phosphorylation and Up-regulation of Diacylglycerol Kinase {gamma} via Its Interaction with Protein Kinase C{gamma}.

Y. Yamaguchi, Y. Shirai, T. Matsubara, K. Sanse, M. Kuriyama, N. Oshiro, K.-i. Yoshino, K. Yonezawa, Y. Ono, and N. Saito (2006)
J. Biol. Chem. 281, 31627-31637
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Protein kinase C as a therapeutic target..

B. A. Teicher (2006)
Clin. Cancer Res. 12, 5336-5345
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Phase I Dose Escalation and Pharmacokinetic Study of Enzastaurin, an Oral Protein Kinase C Beta Inhibitor, in Patients With Advanced Cancer.

M. A. Carducci, L. Musib, M. S. Kies, R. Pili, M. Truong, J. R. Brahmer, P. Cole, R. Sullivan, J. Riddle, J. Schmidt, et al. (2006)
J. Clin. Oncol. 24, 4092-4099
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Neurite Outgrowth-promoting Domains of Neuroglycan C, a Brain-specific Chondroitin Sulfate Proteoglycan, and Involvement of Phosphatidylinositol 3-Kinase and Protein Kinase C Signaling Pathways in Neuritogenesis.

K. Nakanishi, S. Aono, K. Hirano, Y. Kuroda, M. Ida, Y. Tokita, F. Matsui, and A. Oohira (2006)
J. Biol. Chem. 281, 24970-24978
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Bile acids stimulate PKC{alpha} autophosphorylation and activation: role in the attenuation of prostaglandin E1-induced cAMP production in human dermal fibroblasts.

M. Le, L. Krilov, J. Meng, K. Chapin-Kennedy, S. Ceryak, and B. Bouscarel (2006)
Am J Physiol Gastrointest Liver Physiol 291, G275-G287
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Protein Kinase C{delta} Is Essential to Maintain CIITA Gene Expression in B Cells.

M.-J. Kwon, J.-W. Soh, and C.-H. Chang (2006)
J. Immunol. 177, 950-956
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Heterogeneity of Cellular Proliferation within Transitional Cell Carcinoma: Correlation of Protein Kinase C Alpha/betaI Expression and Activity.

V. Aaltonen, J. Koivunen, M. Laato, and J. Peltonen (2006)
J. Histochem. Cytochem. 54, 795-806
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The linoleic acid derivative DCP-LA selectively activates PKC-{epsilon}, possibly binding to the phosphatidylserine binding site.

T. Kanno, H. Yamamoto, T. Yaguchi, R. Hi, T. Mukasa, H. Fujikawa, T. Nagata, S. Yamamoto, A. Tanaka, and T. Nishizaki (2006)
J. Lipid Res. 47, 1146-1156
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Combined therapy with PPAR{alpha} agonist and L-carnitine rescues lipotoxic cardiomyopathy due to systemic carnitine deficiency.

T. Asai, K. Okumura, R. Takahashi, H. Matsui, Y. Numaguchi, H. Murakami, R. Murakami, and T. Murohara (2006)
Cardiovasc Res 70, 566-577
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Localization of diacylglycerol lipase-alpha around postsynaptic spine suggests close proximity between production site of an endocannabinoid, 2-arachidonoyl-glycerol, and presynaptic cannabinoid CB1 receptor..

T. Yoshida, M. Fukaya, M. Uchigashima, E. Miura, H. Kamiya, M. Kano, and M. Watanabe (2006)
J. Neurosci. 26, 4740-4751
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Cellular and molecular mechanisms of tissue protection by lipophilic calcium channel blockers.

J. Menne, J.-K. Park, R. Agrawal, C. Lindschau, J. T. Kielstein, T. Kirsch, A. Marx, D. Muller, F. H. Bahlmann, M. Meier, et al. (2006)
FASEB J 20, 994-996
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Inositol phospholipids localized to caveolae in rat heart are regulated by {alpha}1-adrenergic receptors and by ischemia-reperfusion.

A. A. Lanzafame, L. Turnbull, F. Amiramahdi, J. F. Arthur, H. Huynh, and E. A. Woodcock (2006)
Am J Physiol Heart Circ Physiol 290, H2059-H2065
 |  Abstract »  |  Full Text »  |  PDF »

Impaired trafficking of choline transporter-like protein-1 at plasma membrane and inhibition of choline transport in THP-1 monocyte-derived macrophages.

M. D. Fullerton, L. Wagner, Z. Yuan, and M. Bakovic (2006)
Am J Physiol Cell Physiol 290, C1230-C1238
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase C{zeta} Attenuates Hypoxia-induced Proliferation of Fibroblasts by Regulating MAP Kinase Phosphatase-1 Expression.

M. D. Short, S. M. Fox, C. F. Lam, K. R. Stenmark, and M. Das (2006)
Mol. Biol. Cell 17, 1995-2008
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Nuclear Transportation of Diacylglycerol Kinase {gamma} and Its Possible Function in the Nucleus.

T. Matsubara, Y. Shirai, K. Miyasaka, T. Murakami, Y. Yamaguchi, T. Ueyama, M. Kai, F. Sakane, H. Kanoh, T. Hashimoto, et al. (2006)
J. Biol. Chem. 281, 6152-6164
 |  Abstract »  |  Full Text »  |  PDF »

Targeting the signaling pathway of acylation stimulating protein.

M. Maslowska, H. Legakis, F. Assadi, and K. Cianflone (2006)
J. Lipid Res. 47, 643-652
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Neuroendocrine Protein 7B2 Can Be Inactivated by Phosphorylation within the Secretory Pathway.

S.-N. Lee, J. R. Hwang, and I. Lindberg (2006)
J. Biol. Chem. 281, 3312-3320
 |  Abstract »  |  Full Text »  |  PDF »

Unexpected Role of TRPC6 Channel in Familial Nephrotic Syndrome: Does It Have Clinical Implications?.

M. P. Winn, N. Daskalakis, R. F. Spurney, and J. P. Middleton (2006)
J. Am. Soc. Nephrol. 17, 378-387
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Involvement of protein kinase C in crystalline silica-induced activation of the MAP kinase and AP-1 pathway.

M. Ding, C. Huang, Y. Lu, L. Bowman, V. Castranova, and V. Vallyathan (2006)
Am J Physiol Lung Cell Mol Physiol 290, L291-L297
 |  Abstract »  |  Full Text »  |  PDF »

Identification and Characterization of a Novel Human Type II Diacylglycerol Kinase, DGK{kappa}.

S.-i. Imai, M. Kai, S. Yasuda, H. Kanoh, and F. Sakane (2005)
J. Biol. Chem. 280, 39870-39881
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Divergent contractile and structural responses of the murine PKC-{epsilon} null pulmonary circulation to chronic hypoxia.

C. M. Littler, C. A. Wehling, M. J. Wick, K. A. Fagan, C. D. Cool, R. O. Messing, and E. C. Dempsey (2005)
Am J Physiol Lung Cell Mol Physiol 289, L1083-L1093
 |  Abstract »  |  Full Text »  |  PDF »

Activation of G{alpha}q-Coupled Signaling Pathways in Glomerular Podocytes Promotes Renal Injury.

L. Wang, T. A. Fields, K. Pazmino, Q. Dai, J. L. Burchette, D. N. Howell, T. M. Coffman, and R. F. Spurney (2005)
J. Am. Soc. Nephrol. 16, 3611-3622
 |  Abstract »  |  Full Text »  |  PDF »

{beta}-Adrenoreceptors Reactivate Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication via PKA-Dependent Control of Viral RTA.

M. Chang, H. J. Brown, A. Collado-Hidalgo, J. M. Arevalo, Z. Galic, T. L. Symensma, L. Tanaka, H. Deng, J. A. Zack, R. Sun, et al. (2005)
J. Virol. 79, 13538-13547
 |  Abstract »  |  Full Text »  |  PDF »

N-Benzyladriamycin-14-Valerate (AD198) Induces Apoptosis through Protein Kinase C-{delta}-Induced Phosphorylation of Phospholipid Scramblase 3.

Y. He, J. Liu, D. Durrant, H.-S. Yang, T. Sweatman, L. Lothstein, and R. M. Lee (2005)
Cancer Res. 65, 10016-10023
 |  Abstract »  |  Full Text »  |  PDF »

Dietary fish oil attenuates cardiac hypertrophy in lipotoxic cardiomyopathy due to systemic carnitine deficiency.

R. Takahashi, K. Okumura, T. Asai, T. Hirai, H. Murakami, R. Murakami, Y. Numaguchi, H. Matsui, M. Ito, and T. Murohara (2005)
Cardiovasc Res 68, 213-223
 |  Abstract »  |  Full Text »  |  PDF »

Functional analysis of the phospholipase C gene CaPLC1 and two unusual phospholipase C genes, CaPLC2 and CaPLC3, of Candida albicans.

D. Kunze, I. Melzer, D. Bennett, D. Sanglard, D. MacCallum, J. Norskau, D. C. Coleman, F. C. Odds, W. Schafer, and B. Hube (2005)
Microbiology 151, 3381-3394
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Enhancement of Cisplatin Sensitivity of Cisplatin-Resistant Human Cervical Carcinoma Cells by Bryostatin 1.

S. Mohanty, J. Huang, and A. Basu (2005)
Clin. Cancer Res. 11, 6730-6737
 |  Abstract »  |  Full Text »  |  PDF »

Activation of M1 Muscarinic Acetylcholine Receptors Stimulates the Formation of a Multiprotein Complex Centered on TRPC6 Channels.

J. Y. Kim and D. Saffen (2005)
J. Biol. Chem. 280, 32035-32047
 |  Abstract »  |  Full Text »  |  PDF »

Protein Kinase C {beta}II Plays an Essential Role in Dendritic Cell Differentiation and Autoregulates Its Own Expression.

P. J. Cejas, L. M. Carlson, J. Zhang, S. Padmanabhan, D. Kolonias, I. Lindner, S. Haley, L. H. Boise, and K. P. Lee (2005)
J. Biol. Chem. 280, 28412-28423
 |  Abstract »  |  Full Text »  |  PDF »

N-Methyl-D-aspartate Attenuates CXCR2-Mediated Neuroprotection through Enhancing the Receptor Phosphorylation and Blocking the Receptor Recycling.

Q. Luo, Y. Ding, K. Watson, J. Zhang, and G.-H. Fan (2005)
Mol. Pharmacol. 68, 528-537
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Diacylglycerol-lactone Shows Marked Selectivity in Vitro among C1 Domains of Protein Kinase C (PKC) Isoforms {alpha} and {delta} as Well as Selectivity for RasGRP Compared with PKC{alpha}.

Y. Pu, N. A. Perry, D. Yang, N. E. Lewin, N. Kedei, D. C. Braun, S. H. Choi, P. M. Blumberg, S. H. Garfield, J. C. Stone, et al. (2005)
J. Biol. Chem. 280, 27329-27338
 |  Abstract »  |  Full Text »  |  PDF »

StarD10, a START Domain Protein Overexpressed in Breast Cancer, Functions as a Phospholipid Transfer Protein.

M. A. Olayioye, S. Vehring, P. Muller, A. Herrmann, J. Schiller, C. Thiele, G. J. Lindeman, J. E. Visvader, and T. Pomorski (2005)
J. Biol. Chem. 280, 27436-27442
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of the Yeast Choline Kinase by Protein Kinase C: IDENTIFICATION OF Ser25 AND Ser30 AS MAJOR SITES OF PHOSPHORYLATION.

M.-G. Choi, V. Kurnov, M. C. Kersting, A. Sreenivas, and G. M. Carman (2005)
J. Biol. Chem. 280, 26105-26112
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Reinforcing the mucus: a new therapeutic approach for ulcerative colitis?.

P R Gibson and J G Muir (2005)
Gut 54, 900-903
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Epac Mediates a cAMP-to-PKC Signaling in Inflammatory Pain: An Isolectin B4(+) Neuron-Specific Mechanism.

T. B. Hucho, O. A. Dina, and J. D. Levine (2005)
J. Neurosci. 25, 6119-6126
 |  Abstract »  |  Full Text »  |  PDF »

Role of p90 Ribosomal S6 Kinase (p90RSK) in Reactive Oxygen Species and Protein Kinase C {beta} (PKC-{beta})-mediated Cardiac Troponin I Phosphorylation.

S. Itoh, B. Ding, C. P. Bains, N. Wang, Y. Takeishi, T. Jalili, G. L. King, R. A. Walsh, C. Yan, and J.-i. Abe (2005)
J. Biol. Chem. 280, 24135-24142
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Formation of the head organizer in hydra involves the canonical Wnt pathway.

M. Broun, L. Gee, B. Reinhardt, and H. R. Bode (2005)
Development 132, 2907-2916
 |  Abstract »  |  Full Text »  |  PDF »

Surfactant phospholipid DPPC downregulates monocyte respiratory burst via modulation of PKC.

A. Tonks, J. Parton, A. J. Tonks, R. H. K. Morris, A. Finall, K. P. Jones, and S. K. Jackson (2005)
Am J Physiol Lung Cell Mol Physiol 288, L1070-L1080
 |  Abstract »  |  Full Text »  |  PDF »

Isolation of a Drosophila Gene Coding for a Protein Containing a Novel Phosphatidylserine-Binding Motif.

Y. Nakai, Y. Nomura, T. Sato, A. Shiratsuchi, and Y. Nakanishi (2005)
J. Biochem. 137, 593-599
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Regulation of Highly Cytokinergic IgE-Induced Mast Cell Adhesion by Src, Syk, Tec, and Protein Kinase C Family Kinases.

J. Kitaura, K. Eto, T. Kinoshita, Y. Kawakami, M. Leitges, C. A. Lowell, and T. Kawakami (2005)
J. Immunol. 174, 4495-4504
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Increased Collagen Deposition and Diastolic Dysfunction but Preserved Myocardial Hypertrophy After Pressure Overload in Mice Lacking PKC{epsilon}.

G. Klein, A. Schaefer, D. Hilfiker-Kleiner, D. Oppermann, P. Shukla, A. Quint, E. Podewski, A. Hilfiker, F. Schroder, M. Leitges, et al. (2005)
Circ. Res. 96, 748-755
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Opposing Effects of Protein Kinase C{alpha} and Protein Kinase C{epsilon} on Collagen Expression by Human Lung Fibroblasts Are Mediated via MEK/ERK and Caveolin-1 Signaling.

E. Tourkina, P. Gooz, J. Pannu, M. Bonner, D. Scholz, S. Hacker, R. M. Silver, M. Trojanowska, and S. Hoffman (2005)
J. Biol. Chem. 280, 13879-13887
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Myocardial 11C-Diacylglycerol Accumulation and Left Ventricular Remodeling in Patients After Myocardial Infarction.

H. Otani, Y. Kagaya, Y. Imahori, S. Yasuda, R. Fujii, M. Chida, S. Namiuchi, M. Takeda, M. Sakuma, J. Watanabe, et al. (2005)
J. Nucl. Med. 46, 553-559
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Variable expression of protein kinase C{varepsilon} in human melanoma cells regulates sensitivity to TRAIL-induced apoptosis.

S. Gillespie, X. D. Zhang, and P. Hersey (2005)
Mol. Cancer Ther. 4, 668-676
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The Carboxyl Terminus of VEGFR-2 Is Required for PKC-mediated Down-Regulation.

A. J. Singh, R. D. Meyer, H. Band, and N. Rahimi (2005)
Mol. Biol. Cell 16, 2106-2118
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Requirement of Aldose Reductase for the Hyperglycemic Activation of Protein Kinase C and Formation of Diacylglycerol in Vascular Smooth Muscle Cells.

K. V. Ramana, B. Friedrich, R. Tammali, M. B. West, A. Bhatnagar, and S. K. Srivastava (2005)
Diabetes 54, 818-829
 |  Abstract »  |  Full Text »  |  PDF »

Negative Regulation of TRPC3 Channels by Protein Kinase C-Mediated Phosphorylation of Serine 712.

M. Trebak, N. Hempel, B. J. Wedel, J. T. Smyth, G. St. J. Bird, and J. W. Putney Jr. (2005)
Mol. Pharmacol. 67, 558-563
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Domains, Amino Acid Residues, and New Isoforms of Caenorhabditis elegans Diacylglycerol Kinase 1 (DGK-1) Important for Terminating Diacylglycerol Signaling in Vivo.

A. M. Jose and M. R. Koelle (2005)
J. Biol. Chem. 280, 2730-2736
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Specific Modulation of Na+ Channels in Hippocampal Neurons by Protein Kinase C{epsilon}.

Y. Chen, A. R. Cantrell, R. O. Messing, T. Scheuer, and W. A. Catterall (2005)
J. Neurosci. 25, 507-513
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Overexpression of Protein Kinase C-{epsilon} in the Mouse Epidermis Leads to a Spontaneous Myeloproliferative-Like Disease.

D. L. Wheeler, P. J. Reddig, K. J. Ness, C. P. Leith, T. D. Oberley, and A. K. Verma (2005)
Am. J. Pathol. 166, 117-126
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Protein Kinase C Isoforms Differentially Phosphorylate Human Choline Acetyltransferase Regulating Its Catalytic Activity.

T. Dobransky, A. Doherty-Kirby, A.-R. Kim, D. Brewer, G. Lajoie, and R. J. Rylett (2004)
J. Biol. Chem. 279, 52059-52068
 |  Abstract »  |  Full Text »  |  PDF »