Science 16 October 1992: Vol. 258. no. 5081, pp. 424 - 429 DOI: 10.1126/science.1411535

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Articles

A Small Molecule Disruptor of Rb/Raf-1 Interaction Inhibits Cell Proliferation, Angiogenesis, and Growth of Human Tumor Xenografts in Nude Mice.

R. Kinkade, P. Dasgupta, A. Carie, D. Pernazza, M. Carless, S. Pillai, N. Lawrence, S. M. Sebti, and S. Chellappan (2008)
Cancer Res. 68, 3810-3818
 |  Abstract »  |  Full Text »  |  PDF »

pRB-E2F1 Complexes Are Resistant to Adenovirus E1A-Mediated Disruption.

L. A. Seifried, S. Talluri, M. Cecchini, L. M. Julian, J. S. Mymryk, and F. A. Dick (2008)
J. Virol. 82, 4511-4520
 |  Abstract »  |  Full Text »  |  PDF »

Dual Specificity Phosphatase 1/CL100 Is a Direct Transcriptional Target of E2F-1 in the Apoptotic Response to Oxidative Stress.

J. Wang, D. P. Yin, Y.-X. Liu, R. Baer, and Y. Yin (2007)
Cancer Res. 67, 6737-6744
 |  Abstract »  |  Full Text »  |  PDF »

A Molecular Link between E2F-1 and the MAPK Cascade.

J. Wang, W. H. Shen, Y. J. Jin, P. W. Brandt-Rauf, and Y. Yin (2007)
J. Biol. Chem. 282, 18521-18531
 |  Abstract »  |  Full Text »  |  PDF »

Cardiac Myocyte Cell Cycle Control in Development, Disease, and Regeneration.

P. Ahuja, P. Sdek, and W. R. MacLellan (2007)
Physiol Rev 87, 521-544
 |  Abstract »  |  Full Text »  |  PDF »

Re-oxygenation Improves Hypoxia-induced Pulp Cell Arrest.

Y. Ueno, C. Kitamura, M. Terashita, and T. Nishihara (2006)
J. Dent. Res. 85, 824-828
 |  Abstract »  |  Full Text »  |  PDF »

HuR Contributes to Cyclin E1 Deregulation in MCF-7 Breast Cancer Cells.

X. Guo and R. S. Hartley (2006)
Cancer Res. 66, 7948-7956
 |  Abstract »  |  Full Text »  |  PDF »

E2F-1 Overexpression in U2OS Cells Increases Cyclin B1 Levels and cdc2 Kinase Activity and Sensitizes Cells to Antimitotic Agents..

A. J. Russo, P. G. Magro, Z. Hu, W.-W. Li, R. Peters, J. Mandola, D. Banerjee, and J. R. Bertino (2006)
Cancer Res. 66, 7253-7260
 |  Abstract »  |  Full Text »  |  PDF »

Surprising Dependency for Retinoblastoma Protein in Ras-Mediated Tumorigenesis.

J. DeGregori (2006)
Mol. Cell. Biol. 26, 1165-1169
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Adenovirus E1B 55-Kilodalton Protein Is Required for both Regulation of mRNA Export and Efficient Entry into the Late Phase of Infection in Normal Human Fibroblasts.

R. Gonzalez, W. Huang, R. Finnen, C. Bragg, and S. J. Flint (2006)
J. Virol. 80, 964-974
 |  Abstract »  |  Full Text »  |  PDF »

Disruption of the Paternal Necdin Gene Diminishes TrkA Signaling for Sensory Neuron Survival.

K.-i. Kuwako, A. Hosokawa, I. Nishimura, T. Uetsuki, M. Yamada, S. Nada, M. Okada, and K. Yoshikawa (2005)
J. Neurosci. 25, 7090-7099
 |  Abstract »  |  Full Text »  |  PDF »

p400 Is Required for E1A to Promote Apoptosis.

A. V. Samuelson, M. Narita, H.-M. Chan, J. Jin, E. de Stanchina, M. E. McCurrach, M. Narita, M. Fuchs, D. M. Livingston, and S. W. Lowe (2005)
J. Biol. Chem. 280, 21915-21923
 |  Abstract »  |  Full Text »  |  PDF »

Manganese Superoxide Dismutase Protects the Proliferative Capacity of Confluent Normal Human Fibroblasts.

E. H. Sarsour, M. Agarwal, T. K. Pandita, L. W. Oberley, and P. C. Goswami (2005)
J. Biol. Chem. 280, 18033-18041
 |  Abstract »  |  Full Text »  |  PDF »

The Tumor-specific Hyperactive Forms of Cyclin E Are Resistant to Inhibition by p21 and p27.

H. Wingate, N. Zhang, M. J. McGarhen, I. Bedrosian, J. W. Harper, and K. Keyomarsi (2005)
J. Biol. Chem. 280, 15148-15157
 |  Abstract »  |  Full Text »  |  PDF »

Adult Neurogenesis: From Precursors to Network and Physiology.

D. N. Abrous, M. Koehl, and M. Le Moal (2005)
Physiol Rev 85, 523-569
 |  Abstract »  |  Full Text »  |  PDF »

Epstein-Barr Virus Lytic Replication Elicits ATM Checkpoint Signal Transduction While Providing an S-phase-like Cellular Environment.

A. Kudoh, M. Fujita, L. Zhang, N. Shirata, T. Daikoku, Y. Sugaya, H. Isomura, Y. Nishiyama, and T. Tsurumi (2005)
J. Biol. Chem. 280, 8156-8163
 |  Abstract »  |  Full Text »  |  PDF »

Hypermethylation of Growth Arrest DNA Damage-Inducible Gene 45 {beta} Promoter in Human Hepatocellular Carcinoma.

W. Qiu, B. Zhou, H. Zou, X. Liu, P. G. Chu, R. Lopez, J. Shih, C. Chung, and Y. Yen (2004)
Am. J. Pathol. 165, 1689-1699
 |  Abstract »  |  Full Text »  |  PDF »

p55, the Drosophila Ortholog of RbAp46/RbAp48, Is Required for the Repression of dE2F2/RBF-Regulated Genes.

B. Taylor-Harding, U. K. Binne, M. Korenjak, A. Brehm, and N. J. Dyson (2004)
Mol. Cell. Biol. 24, 9124-9136
 |  Abstract »  |  Full Text »  |  PDF »

E2f1 Mutation Induces Early Onset of Diabetes and Sjogren's Syndrome in Nonobese Diabetic Mice.

M. A. Salam, K. Matin, N. Matsumoto, Y. Tsuha, N. Hanada, and H. Senpuku (2004)
J. Immunol. 173, 4908-4918
 |  Abstract »  |  Full Text »  |  PDF »

Aberrant Regulation of Survivin by the RB/E2F Family of Proteins.

Y. Jiang, H. I. Saavedra, M. P. Holloway, G. Leone, and R. A. Altura (2004)
J. Biol. Chem. 279, 40511-40520
 |  Abstract »  |  Full Text »  |  PDF »

Bone Morphogenetic Protein 2-Induced Osteoblast Differentiation Requires Smad-Mediated Down-Regulation of Cdk6.

T. Ogasawara, H. Kawaguchi, S. Jinno, K. Hoshi, K. Itaka, T. Takato, K. Nakamura, and H. Okayama (2004)
Mol. Cell. Biol. 24, 6560-6568
 |  Abstract »  |  Full Text »  |  PDF »

siRNA-mediated gene silencing: a global genome view.

D. Semizarov, P. Kroeger, and S. Fesik (2004)
Nucleic Acids Res. 32, 3836-3845
 |  Abstract »  |  Full Text »  |  PDF »

The Proapoptotic Gene SIVA Is a Direct Transcriptional Target for the Tumor Suppressors p53 and E2F1.

A. Fortin, J. G. MacLaurin, N. Arbour, S. P. Cregan, N. Kushwaha, S. M. Callaghan, D. S. Park, P. R. Albert, and R. S. Slack (2004)
J. Biol. Chem. 279, 28706-28714
 |  Abstract »  |  Full Text »  |  PDF »

Heregulin Regulates the Ability of the ErbB3-binding Protein Ebp1 to Bind E2F Promoter Elements and Repress E2F-mediated Transcription.

Y. Zhang and A. W. Hamburger (2004)
J. Biol. Chem. 279, 26126-26133
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Nucleolar-Related Proteins in Porcine Preimplantation Embryos Produced In Vivo and In Vitro.

B. Bjerregaard, C. Wrenzycki, F. Strejcek, J. Laurincik, P. Holm, R. L. Ochs, C. Rosenkranz, H. Callesen, D. Rath, H. Niemann, et al. (2004)
Biol Reprod 70, 867-876
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Cyclin E Renders Cyclin D-CDK4 Dispensable for Inactivation of the Retinoblastoma Tumor Suppressor Protein, Activation of E2F, and G1-S Phase Progression.

S. M. Keenan, N. H. Lents, and J. J. Baldassare (2004)
J. Biol. Chem. 279, 5387-5396
 |  Abstract »  |  Full Text »  |  PDF »

Down-regulation of nuclear protein ICBP90 by p53/p21Cip1/WAF1-dependent DNA-damage checkpoint signals contributes to cell cycle arrest at G1/S transition.

Y. Arima, T. Hirota, C. Bronner, M. Mousli, T. Fujiwara, S.-i. Niwa, H. Ishikawa, and H. Saya (2004)
Genes Cells 9, 131-142
 |  Abstract »  |  Full Text »  |  PDF »

Rb regulates C/EBP{beta}-DNA-binding activity during 3T3-L1 adipogenesis.

K. A. Cole, A. W. Harmon, J. B. Harp, and Y. M. Patel (2004)
Am J Physiol Cell Physiol 286, C349-C354
 |  Abstract »  |  Full Text »

Inhibition of S-Phase Cyclin-Dependent Kinase Activity Blocks Expression of Epstein-Barr Virus Immediate-Early and Early Genes, Preventing Viral Lytic Replication.

A. Kudoh, T. Daikoku, Y. Sugaya, H. Isomura, M. Fujita, T. Kiyono, Y. Nishiyama, and T. Tsurumi (2004)
J. Virol. 78, 104-115
 |  Abstract »  |  Full Text »  |  PDF »

A truncated HMGA1 gene induces proliferation of the 3T3-L1 pre-adipocytic cells: a model of human lipomas.

G. M. Pierantoni, S. Battista, F. Pentimalli, M. Fedele, R. Visone, A. Federico, M. Santoro, G. Viglietto, and A. Fusco (2003)
Carcinogenesis 24, 1861-1869
 |  Abstract »  |  Full Text »  |  PDF »

Cdc42 Promotes G1 Progression through p70 S6 Kinase-mediated Induction of Cyclin E Expression.

M. M. Chou, J. M. Masuda-Robens, and M. L. Gupta (2003)
J. Biol. Chem. 278, 35241-35247
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin D2 Compensates for the Loss of Cyclin D1 in Estrogen-Induced Mouse Uterine Epithelial Cell Proliferation.

B. Chen and J. W. Pollard (2003)
Mol. Endocrinol. 17, 1368-1381
 |  Abstract »  |  Full Text »  |  PDF »

mRNA Expression Levels of E2F Transcription Factors Correlate with Dihydrofolate Reductase, Reduced Folate Carrier, and Thymidylate Synthase mRNA Expression in Osteosarcoma.

R. Sowers, J. Toguchida, J. Qin, P. A. Meyers, J. H. Healey, A. Huvos, D. Banerjee, J. R. Bertino, and R. Gorlick (2003)
Mol. Cancer Ther. 2, 535-541
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Models in Applied Physiology: Invited Review: Effect of oxygen deprivation on cell cycle activity: a profile of delay and arrest.

R. M. Douglas and G. G. Haddad (2003)
J Appl Physiol 94, 2068-2083
 |  Abstract »  |  Full Text »  |  PDF »

NF-kappa B-dependent Induction of Cyclin D1 by Retinoblastoma Protein (pRB) Family Proteins and Tumor-derived pRB Mutants.

T. Takebayashi, H. Higashi, H. Sudo, H. Ozawa, E. Suzuki, O. Shirado, H. Katoh, and M. Hatakeyama (2003)
J. Biol. Chem. 278, 14897-14905
 |  Abstract »  |  Full Text »  |  PDF »

Repression of E2F1-mediated transcription by the ErbB3 binding protein Ebp1 involves histone deacetylases.

Y. Zhang, N. Woodford, X. Xia, and A. W. Hamburger (2003)
Nucleic Acids Res. 31, 2168-2177
 |  Abstract »  |  Full Text »  |  PDF »

The Cyclin D1-dependent Kinase Associates with the Pre-replication Complex and Modulates RB{middle dot}MCM7 Binding.

A. B. Gladden and J. A. Diehl (2003)
J. Biol. Chem. 278, 9754-9760
 |  Abstract »  |  Full Text »  |  PDF »

Host DNA Replication Is Induced by Geminivirus Infection of Differentiated Plant Cells.

S. Nagar, L. Hanley-Bowdoin, and D. Robertson (2002)
PLANT CELL 14, 2995-3007
 |  Abstract »  |  Full Text »  |  PDF »

Two E2F Elements Regulate the Proliferating Cell Nuclear Antigen Promoter Differently during Leaf Development.

E. M. Egelkrout, L. Mariconti, S. B. Settlage, R. Cella, D. Robertson, and L. Hanley-Bowdoin (2002)
PLANT CELL 14, 3225-3236
 |  Abstract »  |  Full Text »  |  PDF »

Unbiased Analysis of RB-mediated Transcriptional Repression Identifies Novel Targets and Distinctions from E2F Action.

M. P. Markey, S. P. Angus, M. W. Strobeck, S. L. Williams, R. W. Gunawardena, B. J. Aronow, and E. S. Knudsen (2002)
Cancer Res. 62, 6587-6597
 |  Abstract »  |  Full Text »  |  PDF »

Active Nuclear Import and Export Pathways Regulate E2F-5 Subcellular Localization.

M. D. Apostolova, I. A. Ivanova, C. Dagnino, S. J. A. D'Souza, and L. Dagnino (2002)
J. Biol. Chem. 277, 34471-34479
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Cyclin-Dependent Kinase 1 by Purines and Pyrrolo[2,3-d]Pyrimidines Does Not Correlate with Antiviral Activity.

D. L. Evers, J. M. Breitenbach, K. Z. Borysko, L. B. Townsend, and J. C. Drach (2002)
Antimicrob. Agents Chemother. 46, 2470-2476
 |  Abstract »  |  Full Text »  |  PDF »

E2F1 Induces Phosphorylation of p53 That Is Coincident with p53 Accumulation and Apoptosis.

H. A. Rogoff, M. T. Pickering, M. E. Debatis, S. Jones, and T. F. Kowalik (2002)
Mol. Cell. Biol. 22, 5308-5318
 |  Abstract »  |  Full Text »  |  PDF »

cdk4 Deficiency Inhibits Skin Tumor Development but Does Not Affect Normal Keratinocyte Proliferation.

M. L. Rodriguez-Puebla, P. L. Miliani de Marval, M. LaCava, D. S. Moons, H. Kiyokawa, and C. J. Conti (2002)
Am. J. Pathol. 161, 405-411
 |  Abstract »  |  Full Text »  |  PDF »

Cell Cycle Proteins Exhibit Altered Expression Patterns in Lentiviral-Associated Encephalitis.

K. L. Jordan-Sciutto, G. Wang, M. Murphey-Corb, and C. A. Wiley (2002)
J. Neurosci. 22, 2185-2195
 |  Abstract »  |  Full Text »  |  PDF »

Novel Immediate-Early Protein IE19 of Human Cytomegalovirus Activates the Origin Recognition Complex I Promoter in a Cooperative Manner with IE72.

M. Shirakata, M. Terauchi, M. Ablikim, K.-I. Imadome, K. Hirai, T. Aso, and Y. Yamanashi (2002)
J. Virol. 76, 3158-3167
 |  Abstract »  |  Full Text »  |  PDF »

Induction of cytostasis in mammary carcinoma cells treated with the anticancer agent perillyl alcohol.

W. Shi and M. N. Gould (2002)
Carcinogenesis 23, 131-142
 |  Abstract »  |  Full Text »  |  PDF »

PML-RARalpha Alleviates the Transcriptional Repression Mediated by Tumor Suppressor Rb.

M. M. Khan, T. Nomura, H. Kim, S. C. Kaul, R. Wadhwa, S. Zhong, P. Paolo Pandolfi, and S. Ishii (2001)
J. Biol. Chem. 276, 43491-43494
 |  Abstract »  |  Full Text »  |  PDF »

E2F-1 Up-Regulates c-Myc and p14ARF and Induces Apoptosis in Colon Cancer Cells.

M. J. Elliott, Y. B. Dong, H. Yang, and K. M. McMasters (2001)
Clin. Cancer Res. 7, 3590-3597
 |  Abstract »  |  Full Text »  |  PDF »

Angiotensin II-induced Transcriptional Activation of the Cyclin D1 Gene Is Mediated by Egr-1 in CHO-AT1A Cells.

L. Guillemot, A. Levy, M. Raymondjean, and B. Rothhut (2001)
J. Biol. Chem. 276, 39394-39403
 |  Abstract »  |  Full Text »  |  PDF »

Chemopreventive Property of a Soybean Peptide (Lunasin) That Binds to Deacetylated Histones and Inhibits Acetylation.

A. F. Galvez, N. Chen, J. Macasieb, and B. O. de Lumen (2001)
Cancer Res. 61, 7473-7478
 |  Abstract »  |  Full Text »  |  PDF »

Cyclooxygenase-independent actions of cyclooxygenase inhibitors.

I. TEGEDER, J. PFEILSCHIFTER, and G. GEISSLINGER (2001)
FASEB J 15, 2057-2072
 |  Abstract »  |  Full Text »  |  PDF »

New Insights into the Role of Nuclear Factor-{kappa}B in Cell Growth Regulation.

F. Chen, V. Castranova, and X. Shi (2001)
Am. J. Pathol. 159, 387-397
 |  Abstract »  |  Full Text »

E2F mediates induction of the Sp1-controlled promoter of the human DNA polymerase {{epsilon}} B-subunit gene POLE2.

D. Huang, M. Jokela, J. Tuusa, S. Skog, K. Poikonen, and J. E. Syvaoja (2001)
Nucleic Acids Res. 29, 2810-2821
 |  Abstract »  |  Full Text »  |  PDF »

Transgenic Expression of Cyclin-Dependent Kinase 4 Results in Epidermal Hyperplasia, Hypertrophy, and Severe Dermal Fibrosis.

P. L. Miliani de Marval, I. B. Gimenez-Conti, M. LaCava, L. A. Martinez, C. J. Conti, and M. L. Rodriguez-Puebla (2001)
Am. J. Pathol. 159, 369-379
 |  Abstract »  |  Full Text »  |  PDF »

Risks for Incident Human Papillomavirus Infection and Low-Grade Squamous Intraepithelial Lesion Development in Young Females.

A.-B. Moscicki, N. Hills, S. Shiboski, K. Powell, N. Jay, E. Hanson, S. Miller, L. Clayton, S. Farhat, J. Broering, et al. (2001)
JAMA 285, 2995-3002
 |  Abstract »  |  Full Text »  |  PDF »

Loss of HCF-1-Chromatin Association Precedes Temperature-Induced Growth Arrest of tsBN67 Cells.

J. Wysocka, P. T. Reilly, and W. Herr (2001)
Mol. Cell. Biol. 21, 3820-3829
 |  Abstract »  |  Full Text »

Transduction of Antisense Cyclin D1 Using Two-step Gene Transfer Inhibits the Growth of Rat Hepatoma Cells.

H. Uto, A. Ido, A. Moriuchi, Y. Onaga, K. Nagata, M. Onaga, Y. Tahara, T. Hori, S. Hirono, K. Hayashi, et al. (2001)
Cancer Res. 61, 4779-4783
 |  Abstract »  |  Full Text »  |  PDF »

Death-Defying Pathways Linking Cell Cycle and Apoptosis.

L. A. Kirshenbaum (2001)
Circ. Res. 88, 978-980
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Cyclin-dependent Kinase Inhibitor p27Kip1 Is Required for Mouse Mammary Gland Morphogenesis and Function.

R. S. Muraoka, A. E.G. Lenferink, J. Simpson, D. M. Brantley, L. R. Roebuck, F. M. Yakes, and C. L. Arteaga (2001)
J. Cell Biol. 153, 917-932
 |  Abstract »  |  Full Text »  |  PDF »

Accumulation of Cyclin E Is Not a Prerequisite for Passage through the Restriction Point.

S. V. Ekholm, P. Zickert, S. I. Reed, and A. Zetterberg (2001)
Mol. Cell. Biol. 21, 3256-3265
 |  Abstract »  |  Full Text »

E2F-dependent transcription of the raf proto-oncogene during Drosophila development.

E.-J. Kwon, E.-J. Oh, Y.-S. Kim, F. Hirose, K. Ohno, Y. Nishida, A. Matsukage, M. Yamaguchi, and M.-A. Yoo (2001)
Nucleic Acids Res. 29, 1808-1814
 |  Abstract »  |  Full Text »  |  PDF »

Nitric oxide-induced cytostasis and cell cycle arrest of a human breast cancer cell line (MDA-MB-231): Potential role of cyclin D1.

S. Pervin, R. Singh, and G. Chaudhuri (2001)
PNAS 98, 3583-3588
 |  Abstract »  |  Full Text »  |  PDF »

Effect on Polyomavirus T-Antigen Function of Mutations in a Conserved Leucine-Rich Segment of the DnaJ Domain.

H. Li, K. Söderbärg, H. Houshmand, Z.-Y. You, and G. Magnusson (2001)
J. Virol. 75, 2253-2261
 |  Abstract »  |  Full Text »

Cervical Cancer: Prevention, Diagnosis, and Therapeutics.

M. F. Janicek and H. E. Averette (2001)
CA Cancer J Clin 51, 92-114
 |  Abstract »  |  Full Text »  |  PDF »

UCN-01 Suppresses E2F-1 Mediated by Ubiquitin-proteasome-dependent Degradation.

C.-T. Hsueh, Y.-C. Wu, and G. K. Schwartz (2001)
Clin. Cancer Res. 7, 669-674
 |  Abstract »  |  Full Text »

Growth Suppression of Human Coronary Vascular Smooth Muscle Cells by Gene Transfer of the Transcription Factor E2F-1.

H. S. Shelat, T.-J. Liu, D. L. Hickman-Bick, M. K. Barnhart, T. Vida, P. M. Dillard, J. T. Willerson, and P. Zoldhelyi (2001)
Circulation 103, 407-414
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Vascular Smooth Muscle Cell Proliferation by Sodium Salicylate Mediated by Upregulation of p21Waf1 and p27Kip1.

D. E. Marra, T. Simoncini, and J. K. Liao (2000)
Circulation 102, 2124-2130
 |  Abstract »  |  Full Text »  |  PDF »

The Expression of p18INK4 and p27kip1 Cyclin-Dependent Kinase Inhibitors Is Regulated Differently During Human B Cell Differentiation.

N. Schrantz, G. E. Beney, M. T. Auffredou, M. F. Bourgeade, G. Leca, and A. Vazquez (2000)
J. Immunol. 165, 4346-4352
 |  Abstract »  |  Full Text »  |  PDF »

E2F-Rb Complexes Assemble and Inhibit cdc25A Transcription in Cervical Carcinoma Cells following Repression of Human Papillomavirus Oncogene Expression.

L. Wu, E. C. Goodwin, L. K. Naeger, E. Vigo, K. Galaktionov, K. Helin, and D. DiMaio (2000)
Mol. Cell. Biol. 20, 7059-7067
 |  Abstract »  |  Full Text »

Role of the LXCXE Binding Site in Rb Function.

A. Dahiya, M. R. Gavin, R. X. Luo, and D. C. Dean (2000)
Mol. Cell. Biol. 20, 6799-6805
 |  Abstract »  |  Full Text »

Cyclin D2 Overexpression in Transgenic Mice Induces Thymic and Epidermal Hyperplasia whereas Cyclin D3 Expression Results Only in Epidermal Hyperplasia.

M. L. Rodriguez-Puebla, M. LaCava, P. L. Miliani de Marval, J. L. Jorcano, E. R. Richie, and C. J. Conti (2000)
Am. J. Pathol. 157, 1039-1050
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Cell-Cycle Regulators in Simian Immunodeficiency Virus Encephalitis.

K. L. Jordan-Sciutto, G. Wang, M. Murphy-Corb, and C. A. Wiley (2000)
Am. J. Pathol. 157, 497-507
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Novel E2F3 Product Suggests a Mechanism for Determining Specificity of Repression by Rb Proteins.

G. Leone, F. Nuckolls, S. Ishida, M. Adams, R. Sears, L. Jakoi, A. Miron, and J. R. Nevins (2000)
Mol. Cell. Biol. 20, 3626-3632
 |  Abstract »  |  Full Text »

Mutagenesis of the pRB Pocket Reveals that Cell Cycle Arrest Functions Are Separable from Binding to Viral Oncoproteins.

F. A. Dick, E. Sailhamer, and N. J. Dyson (2000)
Mol. Cell. Biol. 20, 3715-3727
 |  Abstract »  |  Full Text »

Involvement of Retinoblastoma Family Members and E2F/DP Complexes in the Death of Neurons Evoked by DNA Damage.

D. S. Park, E. J. Morris, R. Bremner, E. Keramaris, J. Padmanabhan, M. Rosenbaum, M. L. Shelanski, H. M. Geller, and L. A. Greene (2000)
J. Neurosci. 20, 3104-3114
 |  Abstract »  |  Full Text »  |  PDF »

E2F Family Members Are Differentially Regulated by Reversible Acetylation.

G. Marzio, C. Wagener, M. I. Gutierrez, P. Cartwright, K. Helin, and M. Giacca (2000)
J. Biol. Chem. 275, 10887-10892
 |  Abstract »  |  Full Text »  |  PDF »

Molecular and Genetic Aspects of Lung Cancer.

W. N. ROM, J. G. HAY, T. C. LEE, Y. JIANG, and K.-M. TCHOU-WONG (2000)
Am. J. Respir. Crit. Care Med. 161, 1355-1367
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Cloning and Characterization of a Novel Kruppel-associated Box Family Transcriptional Repressor That Interacts with the Retinoblastoma Gene Product, RB.

S. X. Skapek, D. Jansen, T.-F. Wei, T. McDermott, W. Huang, E. N. Olson, and E. Y.-H. P. Lee (2000)
J. Biol. Chem. 275, 7212-7223
 |  Abstract »  |  Full Text »  |  PDF »

Adeno-Associated Virus Major Rep78 Protein Disrupts Binding of TATA-Binding Protein to the p97 Promoter of Human Papillomavirus Type 16.

P.-F. Su, S.-Y. Chiang, C.-W. Wu, and F. Y.-H. Wu (2000)
J. Virol. 74, 2459-2465
 |  Abstract »  |  Full Text »

Simian Virus 40 Large T Antigen Binds a Novel Bcl-2 Homology Domain 3-containing Proapoptosis Protein in the Cytoplasm.

S.-C. Tsai, K. B. S. Pasumarthi, L. Pajak, M. Franklin, B. Patton, H. Wang, W. J. Henzel, J. T. Stults, and L. J. Field (2000)
J. Biol. Chem. 275, 3239-3246
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A Role for E2F1 in the Induction of Apoptosis during Thymic Negative Selection.

I. García, M. Murga, A. Vicario, S. J. Field, and A. M. Zubiaga (2000)
Cell Growth Differ. 11, 91-98
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Characterization of the Murine Pituitary Tumor Transforming Gene (PTTG) and Its Promoter.

Z. Wang and S. Melmed (2000)
Endocrinology 141, 763-771
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Chromosome condensation induced by geminivirus infection of mature plant cells.

H. Bass, S Nagar, L Hanley-Bowdoin, and D Robertson (2000)
J. Cell Sci. 113, 1149-1160
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A Binding Site for the Transcription Factor Grainyhead/Nuclear Transcription Factor-1 Contributes to Regulation of the Drosophila Proliferating Cell Nuclear Antigen Gene Promoter.

Y. Hayashi, M. Yamagishi, Y. Nishimoto, O. Taguchi, A. Matsukage, and M. Yamaguchi (1999)
J. Biol. Chem. 274, 35080-35088
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Identification of a Portable Repression Domain and an E1A-Responsive Activation Domain in Pax4: a Possible Role of Pax4 as a Transcriptional Repressor in the Pancreas.

Y. Fujitani, Y. Kajimoto, T. Yasuda, T.-A. Matsuoka, H. Kaneto, Y. Umayahara, N. Fujita, H. Watada, J.-I. Miyazaki, Y. Yamasaki, et al. (1999)
Mol. Cell. Biol. 19, 8281-8291
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Induction of Transformation and p53-Dependent Apoptosis by Adenovirus Type 5 E4orf6/7 cDNA.

S. Yamano, T. Tokino, M. Yasuda, M. Kaneuchi, M. Takahashi, Y. Niitsu, K. Fujinaga, and T. Yamashita (1999)
J. Virol. 73, 10095-10103
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Expression of p27kip and Other Cell Cycle Regulators in Malignant Peripheral Nerve Sheath Tumors and Neurofibromas : The Emerging Role of p27kip in MalignantTransformation of Neurofibromas.

H. P. Kourea, C. Cordon-Cardo, M. Dudas, D. Leung, and J. M. Woodruff (1999)
Am. J. Pathol. 155, 1885-1891
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Neuralization of the Xenopus Embryo by Inhibition of p300/ CREB-Binding Protein Function.

Y. Kato, Y. Shi, and X. He (1999)
J. Neurosci. 19, 9364-9373
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Repression of Epstein-Barr Virus EBNA-1 Gene Transcription by pRb during Restricted Latency.

I. K. Ruf and J. Sample (1999)
J. Virol. 73, 7943-7951
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Disruption of Retinoblastoma Protein Family Function by Human Papillomavirus Type 16 E7 Oncoprotein Inhibits Lens Development in Part through E2F-1.

J. McCaffrey, L. Yamasaki, N. J. Dyson, E. Harlow, and A. E. Griep (1999)
Mol. Cell. Biol. 19, 6458-6468
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A mechanism for Rb/p130-mediated transcription repression involving recruitment of the CtBP corepressor.

A. R. Meloni, E. J. Smith, and J. R. Nevins (1999)
PNAS 96, 9574-9579
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