Science 25 September 1992: Vol. 257. no. 5078, pp. 1958 - 1961 DOI: 10.1126/science.1329201

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Articles

{gamma}-Aminobutyric Acid Transporter 1 Negatively Regulates T Cell Activation and Survival through Protein Kinase C-Dependent Signaling Pathways.

Y. Wang, Q. Luo, Y. Xu, D. Feng, J. Fei, Q. Cheng, and L. Xu (2009)
J. Immunol. 183, 3488-3495
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation by Cyclin C/Cyclin-Dependent Kinase 2 following Mitogenic Stimulation of Murine Fibroblasts Inhibits Transcriptional Activity of LSF during G1 Progression.

U. H. Saxena, C. M. H. Powell, J. K. Fecko, R. Cacioppo, H. S. Chou, G. M. Cooper, and U. Hansen (2009)
Mol. Cell. Biol. 29, 2335-2345
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin-Dependent Kinase-Associated Proteins Cks1 and Cks2 Are Essential during Early Embryogenesis and for Cell Cycle Progression in Somatic Cells.

H.-S. Martinsson-Ahlzen, V. Liberal, B. Grunenfelder, S. R. Chaves, C. H. Spruck, and S. I. Reed (2008)
Mol. Cell. Biol. 28, 5698-5709
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of Threonine 61 by Cyclin A/Cdk1 Triggers Degradation of Stem-Loop Binding Protein at the End of S Phase.

M. M. Koseoglu, L. M. Graves, and W. F. Marzluff (2008)
Mol. Cell. Biol. 28, 4469-4479
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin E phosphorylation regulates cell proliferation in hematopoietic and epithelial lineages in vivo.

A. C. Minella, K. R. Loeb, A. Knecht, M. Welcker, B. J. Varnum-Finney, I. D. Bernstein, J. M. Roberts, and B. E. Clurman (2008)
Genes & Dev. 22, 1677-1689
 |  Abstract »  |  Full Text »  |  PDF »

Ca2+ signals coordinate zygotic polarization and cell cycle progression in the brown alga Fucus serratus.

J. H. F. Bothwell, J. Kisielewska, M. J. Genner, M. R. McAinsh, and C. Brownlee (2008)
Development 135, 2173-2181
 |  Abstract »  |  Full Text »  |  PDF »

Gene-expression analysis identifies novel RBL2/p130 target genes in endemic Burkitt lymphoma cell lines and primary tumors.

G. De Falco, E. Leucci, D. Lenze, P. P. Piccaluga, P. P. Claudio, A. Onnis, G. Cerino, J. Nyagol, W. Mwanda, C. Bellan, et al. (2007)
Blood 110, 1301-1307
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Cyclin E overexpression impairs progression through mitosis by inhibiting APCCdh1.

J. M. Keck, M. K. Summers, D. Tedesco, S. Ekholm-Reed, L.-C. Chuang, P. K. Jackson, and S. I. Reed (2007)
J. Cell Biol. 178, 371-385
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Genomic AtCYCD2;1 in Arabidopsis Induces Cell Division at Smaller Cell Sizes: Implications for the Control of Plant Growth.

R. Qi and P. C. L. John (2007)
Plant Physiology 144, 1587-1597
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of a Cyclin E Fragment with Ku70 Regulates Bax-Mediated Apoptosis.

S. Mazumder, D. Plesca, M. Kinter, and A. Almasan (2007)
Mol. Cell. Biol. 27, 3511-3520
 |  Abstract »  |  Full Text »  |  PDF »

Transgenic cyclin E triggers dysplasia and multiple pulmonary adenocarcinomas.

Y. Ma, S. Fiering, C. Black, X. Liu, Z. Yuan, V. A. Memoli, D. J. Robbins, H. A. Bentley, G. J. Tsongalis, E. Demidenko, et al. (2007)
PNAS 104, 4089-4094
 |  Abstract »  |  Full Text »  |  PDF »

Death-effector domain-containing protein DEDD is an inhibitor of mitotic Cdk1/cyclin B1.

S. Arai, K. Miyake, R. Voit, S. Nemoto, E. K. Wakeland, I. Grummt, and T. Miyazaki (2007)
PNAS 104, 2289-2294
 |  Abstract »  |  Full Text »  |  PDF »

p27Kip1 and Cyclin E Expression and Breast Cancer Survival After Treatment With Adjuvant Chemotherapy.

P. L. Porter, W. E. Barlow, I-T. Yeh, M. G. Lin, X. P. Yuan, E. Donato, G. W. Sledge, C. L. Shapiro, J. N. Ingle, C. M. Haskell, et al. (2006)
J Natl Cancer Inst 98, 1723-1731
 |  Abstract »  |  Full Text »  |  PDF »

Docosahexaenoic acid inhibits cancer cell growth via p27Kip1, CDK2, ERK1/ERK2, and retinoblastoma phosphorylation.

N. A. Khan, K. Nishimura, V. Aires, T. Yamashita, D. Oaxaca-Castillo, K. Kashiwagi, and K. Igarashi (2006)
J. Lipid Res. 47, 2306-2313
 |  Abstract »  |  Full Text »  |  PDF »

A Calmodulin-Binding Site on Cyclin E Mediates Ca2+-Sensitive G1/S Transitions in Vascular Smooth Muscle Cells.

J. Choi, A. Chiang, N. Taulier, R. Gros, A. Pirani, and M. Husain (2006)
Circ. Res. 98, 1273-1281
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin A-associated kinase activity is needed for paclitaxel sensitivity.

T. Takahashi, F. Yamasaki, T. Sudo, H. Itamochi, S. Adachi, M. Tamamori-Adachi, and N. T. Ueno (2005)
Mol. Cancer Ther. 4, 1039-1046
 |  Abstract »  |  Full Text »  |  PDF »

The Tumor-specific Hyperactive Forms of Cyclin E Are Resistant to Inhibition by p21 and p27.

H. Wingate, N. Zhang, M. J. McGarhen, I. Bedrosian, J. W. Harper, and K. Keyomarsi (2005)
J. Biol. Chem. 280, 15148-15157
 |  Abstract »  |  Full Text »  |  PDF »

Combined Evaluation of Expressions of Cyclin E and p53 Proteins as Prognostic Factors for Patients with Gastric Cancer.

K. E. Bani-Hani, N. M. Almasri, Y. S. Khader, F. M. Sheyab, and H. N. Karam (2005)
Clin. Cancer Res. 11, 1447-1453
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Anticancer Agent, Decursin, Induces G1 Arrest and Apoptosis in Human Prostate Carcinoma Cells.

D. Yim, R. P. Singh, C. Agarwal, S. Lee, H. Chi, and R. Agarwal (2005)
Cancer Res. 65, 1035-1044
 |  Abstract »  |  Full Text »  |  PDF »

Stimulation of a rat uterine stromal cell line in culture reveals a molecular switch for endocrine-dependent differentiation.

V Rider, T Potapova, G Dai, and M J Soares (2005)
J. Endocrinol. 184, 119-127
 |  Abstract »  |  Full Text »  |  PDF »

Lactoferrin Down-Regulates G1 Cyclin-Dependent Kinases during Growth Arrest of Head and Neck Cancer Cells.

Y. Xiao, C. L. Monitto, K. M. Minhas, and D. Sidransky (2004)
Clin. Cancer Res. 10, 8683-8686
 |  Abstract »  |  Full Text »  |  PDF »

Living with or without cyclins and cyclin-dependent kinases.

C. J. Sherr and J. M. Roberts (2004)
Genes & Dev. 18, 2699-2711
 |  Abstract »  |  Full Text »  |  PDF »

Role for Cdk1 (Cdc2)/Cyclin A in Preventing the Mammalian Origin Recognition Complex's Largest Subunit (Orc1) from Binding to Chromatin during Mitosis.

C.-j. Li, A. Vassilev, and M. L. DePamphilis (2004)
Mol. Cell. Biol. 24, 5875-5886
 |  Abstract »  |  Full Text »  |  PDF »

Deregulation of cyclin E in human cells interferes with prereplication complex assembly.

S. Ekholm-Reed, J. Mendez, D. Tedesco, A. Zetterberg, B. Stillman, and S. I. Reed (2004)
J. Cell Biol. 165, 789-800
 |  Abstract »  |  Full Text »  |  PDF »

The proteasome inhibitor bortezomib synergizes with gemcitabine to block the growth of human 253JB-V bladder tumors in vivo.

A. M. Kamat, T. Karashima, D. W. Davis, L. Lashinger, M. Bar-Eli, R. Millikan, Y. Shen, C. P. N. Dinney, and D. J. McConkey (2004)
Mol. Cancer Ther. 3, 279-290
 |  Abstract »  |  Full Text »

Expression of Cyclin E Renders Cyclin D-CDK4 Dispensable for Inactivation of the Retinoblastoma Tumor Suppressor Protein, Activation of E2F, and G1-S Phase Progression.

S. M. Keenan, N. H. Lents, and J. J. Baldassare (2004)
J. Biol. Chem. 279, 5387-5396
 |  Abstract »  |  Full Text »  |  PDF »

Mutation of hCDC4 Leads to Cell Cycle Deregulation of Cyclin E in Cancer.

S. E. Reed, C. H. Spruck, O. Sangfelt, F. van Drogen, E. Mueller-Holzner, M. Widschwendter, A. Zetterberg, and S. I. Reed (2004)
Cancer Res. 64, 795-800
 |  Abstract »  |  Full Text »  |  PDF »

Estrogens Down-regulate p27Kip1 in Breast Cancer Cells through Skp2 and through Nuclear Export Mediated by the ERK Pathway.

J. S. Foster, R. I. Fernando, N. Ishida, K. I. Nakayama, and J. Wimalasena (2003)
J. Biol. Chem. 278, 41355-41366
 |  Abstract »  |  Full Text »  |  PDF »

The ORC1 Cycle in Human Cells: I. CELL CYCLE-REGULATED OSCILLATION OF HUMAN ORC1.

Y. Tatsumi, S. Ohta, H. Kimura, T. Tsurimoto, and C. Obuse (2003)
J. Biol. Chem. 278, 41528-41534
 |  Abstract »  |  Full Text »  |  PDF »

The spindle checkpoint requires cyclin-dependent kinase activity.

V. D'Angiolella, C. Mari, D. Nocera, L. Rametti, and D. Grieco (2003)
Genes & Dev. 17, 2520-2525
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Synchronization of Interphase Events Depends neither on Mitosis nor on cdk1.

A. Laronne, S. Rotkopf, A. Hellman, Y. Gruenbaum, A. C.G. Porter, and M. Brandeis (2003)
Mol. Biol. Cell 14, 3730-3740
 |  Abstract »  |  Full Text »  |  PDF »

Different Cell Cycle Regulation of Vascular Smooth Muscle in Genetic Hypertension.

F. C. Tanner, H. Greutert, C. Barandier, K. Frischknecht, and T. F. Luscher (2003)
Hypertension 42, 184-188
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin D2 Compensates for the Loss of Cyclin D1 in Estrogen-Induced Mouse Uterine Epithelial Cell Proliferation.

B. Chen and J. W. Pollard (2003)
Mol. Endocrinol. 17, 1368-1381
 |  Abstract »  |  Full Text »  |  PDF »

NPAT Expression Is Regulated by E2F and Is Essential for Cell Cycle Progression.

G. Gao, A. P. Bracken, K. Burkard, D. Pasini, M. Classon, C. Attwooll, M. Sagara, T. Imai, K. Helin, and J. Zhao (2003)
Mol. Cell. Biol. 23, 2821-2833
 |  Abstract »  |  Full Text »  |  PDF »

Sequestration of p27Kip1 protein by cyclin D1 in typical and blastic variants of mantle cell lymphoma (MCL): implications for pathogenesis.

L. Quintanilla-Martinez, T. Davies-Hill, F. Fend, J. Calzada-Wack, L. Sorbara, E. Campo, E. S. Jaffe, and M. Raffeld (2003)
Blood 101, 3181-3187
 |  Abstract »  |  Full Text »  |  PDF »

Inositol hexaphosphate inhibits growth, and induces G1 arrest and apoptotic death of prostate carcinoma DU145 cells: modulation of CDKI-CDK-cyclin and pRb-related protein-E2F complexes.

R. P. Singh, C. Agarwal, and R. Agarwal (2003)
Carcinogenesis 24, 555-563
 |  Abstract »  |  Full Text »  |  PDF »

Human cytomegalovirus immediate-early over protein 2 (IE2)-mediated activation of cyclin E is cell-cycle-independent and forces S-phase entry in IE2-arrested cells.

L. Wiebusch, J. Asmar, R. Uecker, and C. Hagemeier (2003)
J. Gen. Virol. 84, 51-60
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Bovine Papillomavirus Replicative Helicase E1 by the Ubiquitin-Proteasome Pathway.

M.-H. Malcles, N. Cueille, F. Mechali, O. Coux, and C. Bonne-Andrea (2002)
J. Virol. 76, 11350-11358
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of CDC6, Geminin, and CDT1 in Human Cells that Undergo Polyploidization.

R. Bermejo, N. Vilaboa, and C. Cales (2002)
Mol. Biol. Cell 13, 3989-4000
 |  Abstract »  |  Full Text »  |  PDF »

Non-malignant and Tumor-derived Cells Differ in Their Requirement for p27Kip1 in Transforming Growth Factor-beta -mediated G1 Arrest.

J. C. H. Donovan, J. M. Rothenstein, and J. M. Slingerland (2002)
J. Biol. Chem. 277, 41686-41692
 |  Abstract »  |  Full Text »  |  PDF »

The Oncogenic Activity of Cyclin E Is Not Confined to Cdk2 Activation Alone but Relies on Several Other, Distinct Functions of the Protein.

C. Geisen and T. Moroy (2002)
J. Biol. Chem. 277, 39909-39918
 |  Abstract »  |  Full Text »  |  PDF »

Down-regulation of Cdc6, a Cell Cycle Regulatory Gene, in Prostate Cancer.

L. D. Robles, A. R. Frost, M. Davila, A. D. Hutson, W. E. Grizzle, and R. Chakrabarti (2002)
J. Biol. Chem. 277, 25431-25438
 |  Abstract »  |  Full Text »  |  PDF »

Altered p27Kip1 Phosphorylation, Localization, and Function in Human Epithelial Cells Resistant to Transforming Growth Factor {beta}-Mediated G1 Arrest.

S. Ciarallo, V. Subramaniam, W. Hung, J.-H. Lee, R. Kotchetkov, C. Sandhu, A. Milic, and J. M. Slingerland (2002)
Mol. Cell. Biol. 22, 2993-3002
 |  Abstract »  |  Full Text »  |  PDF »

Selenium Modulation of Cell Proliferation and Cell Cycle Biomarkers in Human Prostate Carcinoma Cell Lines.

V. Venkateswaran, L. H. Klotz, and N. E. Fleshner (2002)
Cancer Res. 62, 2540-2545
 |  Abstract »  |  Full Text »  |  PDF »

Proteolytic Cleavage of Cyclin E Leads to Inactivation of Associated Kinase Activity and Amplification of Apoptosis in Hematopoietic Cells.

S. Mazumder, B. Gong, Q. Chen, J. A. Drazba, J. C. Buchsbaum, and A. Almasan (2002)
Mol. Cell. Biol. 22, 2398-2409
 |  Abstract »  |  Full Text »  |  PDF »

A senescence rescue screen identifies BCL6 as an inhibitor of anti-proliferative p19ARF-p53 signaling.

A. Shvarts, T. R. Brummelkamp, F. Scheeren, E. Koh, G. Q. Daley, H. Spits, and R. Bernards (2002)
Genes & Dev. 16, 681-686
 |  Abstract »  |  Full Text »  |  PDF »

Piceatannol, a Natural Analog of Resveratrol, Inhibits Progression through the S Phase of the Cell Cycle in Colorectal Cancer Cell Lines.

F. Wolter, A. Clausnitzer, B. Akoglu, and J. Stein (2002)
J. Nutr. 132, 298-302
 |  Abstract »  |  Full Text »  |  PDF »

Novel localization and possible functions of cyclin E in early sea urchin development.

B. J. Schnackenberg and W. F. Marzluff (2002)
J. Cell Sci. 115, 113-121
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of Cdc25A Phosphatase in Hep3B Hepatoma Cell Growth Inhibition Induced by Novel K Vitamin Analogs.

Z. Wang, E. C. Southwick, M. Wang, S. Kar, K. S. Rosi, C. S. Wilcox, J. S. Lazo, and B. I. Carr (2001)
Cancer Res. 61, 7211-7216
 |  Abstract »  |  Full Text »  |  PDF »

Neither p21WAF1 Nor 14-3-3{sigma} Prevents G2 Progression to Mitotic Catastrophe in Human Colon Carcinoma Cells after DNA Damage, But p21WAF1 Induces Stable G1 Arrest in Resulting Tetraploid Cells.

P. R. Andreassen, F. B. Lacroix, O. D. Lohez, and R. L. Margolis (2001)
Cancer Res. 61, 7660-7668
 |  Abstract »  |  Full Text »  |  PDF »

Cyclooxygenase-independent actions of cyclooxygenase inhibitors.

I. TEGEDER, J. PFEILSCHIFTER, and G. GEISSLINGER (2001)
FASEB J 15, 2057-2072
 |  Abstract »  |  Full Text »  |  PDF »

Accumulation of Cyclin E Is Not a Prerequisite for Passage through the Restriction Point.

S. V. Ekholm, P. Zickert, S. I. Reed, and A. Zetterberg (2001)
Mol. Cell. Biol. 21, 3256-3265
 |  Abstract »  |  Full Text »  |  PDF »

Up-Regulation of Cyclin-dependent Kinase 4/Cyclin D2 Expression but Down-Regulation of Cyclin-dependent Kinase 2/Cyclin E in Testicular Germ Cell Tumors.

B. A. Schmidt, A. Rose, C. Steinhoff, T. Strohmeyer, M. Hartmann, and R. Ackermann (2001)
Cancer Res. 61, 4214-4221
 |  Abstract »  |  Full Text »

A Risk-Stratification Model of Non-Small Cell Lung Cancers Using Cyclin E, Ki-67, and ras p21: Different Roles of G1 Cyclins in Cell Proliferation and Prognosis.

H. Dosaka-Akita, F. Hommura, T. Mishina, S. Ogura, M. Shimizu, H. Katoh, and Y. Kawakami (2001)
Cancer Res. 61, 2500-2504
 |  Abstract »  |  Full Text »

Cyclin E is the Only Cyclin-dependent Kinase 2-associated Cyclin that Predicts Metastasis and Survival in Early Stage Non-Small Cell Lung Cancer.

C. Müller-Tidow, R. Metzger, K. Kügler, S. Diederichs, G. Idos, M. Thomas, B. Dockhorn-Dworniczak, P. M. Schneider, H. P. Koeffler, W. E. Berdel, et al. (2001)
Cancer Res. 61, 647-653
 |  Abstract »  |  Full Text »

Mutation of Cyclin/cdk Phosphorylation Sites in HsCdc6 Disrupts a Late Step in Initiation of DNA Replication in Human Cells.

U. Herbig, J. W. Griffith, and E. Fanning (2000)
Mol. Biol. Cell 11, 4117-4130
 |  Abstract »  |  Full Text »

The Expression of p18INK4 and p27kip1 Cyclin-Dependent Kinase Inhibitors Is Regulated Differently During Human B Cell Differentiation.

N. Schrantz, G. E. Beney, M. T. Auffredou, M. F. Bourgeade, G. Leca, and A. Vazquez (2000)
J. Immunol. 165, 4346-4352
 |  Abstract »  |  Full Text »  |  PDF »

The Paramyxovirus Simian Virus 5 V Protein Slows Progression of the Cell Cycle.

G. Y. Lin and R. A. Lamb (2000)
J. Virol. 74, 9152-9166
 |  Abstract »  |  Full Text »  |  PDF »

Where the cell cycle and histones meet.

M. E. Ewen (2000)
Genes & Dev. 14, 2265-2270
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NPAT links cyclin E-Cdk2 to the regulation of replication-dependent histone gene transcription.

J. Zhao, B. K. Kennedy, B. D. Lawrence, D. A. Barbie, A. G. Matera, J. A. Fletcher, and E. Harlow (2000)
Genes & Dev. 14, 2283-2297
 |  Abstract »  |  Full Text »

Cell cycle-regulated phosphorylation of p220NPAT by cyclin E/Cdk2 in Cajal bodies promotes histone gene transcription.

T. Ma, B. A. Van Tine, Y. Wei, M. D. Garrett, D. Nelson, P. D. Adams, J. Wang, J. Qin, L. T. Chow, and J. W. Harper (2000)
Genes & Dev. 14, 2298-2313
 |  Abstract »  |  Full Text »

Loss of p27Kip1 from Cyclin E/Cyclin-dependent Kinase (CDK) 2 but not from Cyclin D1/CDK4 Complexes in Cells Transformed by Polyamine Biosynthetic Enzymes.

K. Ravanko, K. Järvinen, A. Paasinen-Sohns, and E. Hölttä (2000)
Cancer Res. 60, 5244-5253
 |  Abstract »  |  Full Text »

A U-Rich Element in the 5' Untranslated Region Is Necessary for the Translation of p27 mRNA.

S. S. Millard, A. Vidal, M. Markus, and A. Koff (2000)
Mol. Cell. Biol. 20, 5947-5959
 |  Abstract »  |  Full Text »  |  PDF »

The TSC1 gene product, hamartin, negatively regulates cell proliferation.

A. Miloloza, M. Rosner, M. Nellist, D. Halley, G. Bernaschek, and M. Hengstschlager (2000)
Hum. Mol. Genet. 9, 1721-1727
 |  Abstract »  |  Full Text »  |  PDF »

The Pezcoller Lecture: Cancer Cell Cycles Revisited.

C. J. Sherr (2000)
Cancer Res. 60, 3689-3695
 |  Abstract »  |  Full Text »

Involvement of Cyclins in Cell Proliferation and Their Clinical Implications in Soft Tissue Smooth Muscle Tumors.

T. Noguchi, Y. Dobashi, H. Minehara, M. Itoman, and T. Kameya (2000)
Am. J. Pathol. 156, 2135-2147
 |  Abstract »  |  Full Text »  |  PDF »

Histone Deacetylase Inhibitors Trigger a G2 Checkpoint in Normal Cells That Is Defective in Tumor Cells.

L. Qiu, A. Burgess, D. P. Fairlie, H. Leonard, P. G. Parsons, and B. G. Gabrielli (2000)
Mol. Biol. Cell 11, 2069-2083
 |  Abstract »  |  Full Text »

Stem Cell Factor Inhibits Erythroid Differentiation by Modulating the Activity of G1-Cyclin-dependent Kinase Complexes: A Role for p27 in Erythroid Differentiation Coupled G1 Arrest.

A. Tamir, T. Petrocelli, K. Stetler, W. Chu, J. Howard, B. St. Croix, J. Slingerland, and Y. Ben-David (2000)
Cell Growth Differ. 11, 269-277
 |  Abstract »  |  Full Text »

p16INK4A Mediates Cyclin Dependent Kinase 4 and 6 Inhibition in Senescent Prostatic Epithelial Cells.

C. Sandhu, D. M. Peehl, and J. Slingerland (2000)
Cancer Res. 60, 2616-2622
 |  Abstract »  |  Full Text »

Inducible pRb2/p130 Expression and Growth-suppressive Mechanisms: Evidence of a pRb2/p130, p27Kip1, and Cyclin E Negative Feedback Regulatory Loop.

C. M. Howard, P. P. Claudio, Antonio De Luca, P. Stiegler, F. P. Jori, N. M. Safdar, M. Caputi, K. Khalili, and A. Giordano (2000)
Cancer Res. 60, 2737-2744
 |  Abstract »  |  Full Text »

A Screen for Modifiers of Cyclin E Function in Drosophila melanogaster Identifies Cdk2 Mutations, Revealing the Insignificance of Putative Phosphorylation Sites in Cdk2.

M. E. Lane, M. Elend, D. Heidmann, A. Herr, S. Marzodko, A. Herzig, and C. F. Lehner (2000)
Genetics 155, 233-244
 |  Abstract »  |  Full Text »

P21 and Retinoblastoma Protein Control the Absence of DNA Replication in Terminally Differentiated Muscle Cells.

A. Mal, D. Chattopadhyay, M. K. Ghosh, R. Y.C. Poon, T. Hunter, and M. L. Harter (2000)
J. Cell Biol. 149, 281-292
 |  Abstract »  |  Full Text »  |  PDF »

Ciprofloxacin Mediated Cell Growth Inhibition, S/G2-M Cell Cycle Arrest, and Apoptosis in a Human Transitional Cell Carcinoma of the Bladder Cell Line.

O. Aranha, D. P. Wood Jr., and F. H. Sarkar (2000)
Clin. Cancer Res. 6, 891-900
 |  Abstract »  |  Full Text »

Flavopiridol, a Cyclin-dependent Kinase Inhibitor, Prevents Spindle Inhibitor-induced Endoreduplication in Human Cancer Cells.

M. Motwani, X.-k. Li, and G. K. Schwartz (2000)
Clin. Cancer Res. 6, 924-932
 |  Abstract »  |  Full Text »

Retinoic acid-induced proliferation of lung alveolar epithelial cells is linked to p21CIP1 downregulation.

E. Nabeyrat, S. Corroyer, R. Epaud, V. Besnard, V. Cazals, and A. Clement (2000)
Am J Physiol Lung Cell Mol Physiol 278, L42-L50
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin E Expression, a Potential Prognostic Marker for Non-Small Cell Lung Cancers.

T. Mishina, H. Dosaka-Akita, F. Hommura, M. Nishi, T. Kojima, S. Ogura, M. Shimizu, H. Katoh, and Y. Kawakami (2000)
Clin. Cancer Res. 6, 11-16
 |  Abstract »  |  Full Text »

The Potential of Soybean Foods as a Chemoprevention Approach for Human Urinary Tract Cancer.

S.-J. Su, T.-M. Yeh, H.-Y. Lei, and N.-H. Chow (2000)
Clin. Cancer Res. 6, 230-236
 |  Abstract »  |  Full Text »

Rapid ATM-dependent phosphorylation of MDM2 precedes p53 accumulation in response to DNA damage.

R. Khosravi, R. Maya, T. Gottlieb, M. Oren, Y. Shiloh, and D. Shkedy (1999)
PNAS 96, 14973-14977
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Roles for PP1 and PP2A in Phosphorylation of the Retinoblastoma Protein. PP2A REGULATES THE ACTIVITIES OF G1 CYCLIN-DEPENDENT KINASES.

Y. Yan and M. C. Mumby (1999)
J. Biol. Chem. 274, 31917-31924
 |  Abstract »  |  Full Text »  |  PDF »

Microinjection of Anti-p21 Antibodies Induces Senescent Hs68 Human Fibroblasts to Synthesize DNA but not To Divide.

Y. Ma, S. A. Prigent, T. L. Born, C. R. Monell, J. R. Feramisco, and B. L. Bertolaet (1999)
Cancer Res. 59, 5341-5348
 |  Abstract »  |  Full Text »  |  PDF »

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells.

J. D. Singer, M. Gurian-West, B. Clurman, and J. M. Roberts (1999)
Genes & Dev. 13, 2375-2387
 |  Abstract »  |  Full Text »

c-Myc Overexpression Uncouples DNA Replication from Mitosis.

Q. Li and C. V. Dang (1999)
Mol. Cell. Biol. 19, 5339-5351
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of cyclin E gene expression by the human papillomavirus type 16 E7 oncoprotein.

B. Vogt, K. Zerfaß-Thome, A. Schulze, J. W. Botz, W. Zwerschke, and P. Jansen-Dürr (1999)
J. Gen. Virol. 80, 2103-2113
 |  Abstract »  |  Full Text »

Cell Cycle Arrest and Inhibition of Anoikis by Galectin-3 in Human Breast Epithelial Cells.

H.-R. C. Kim, H.-M. Lin, H. Biliran, and A. Raz (1999)
Cancer Res. 59, 4148-4154
 |  Abstract »  |  Full Text »  |  PDF »

c-Myc Regulates Cyclin D-Cdk4 and -Cdk6 Activity but Affects Cell Cycle Progression at Multiple Independent Points.

M. K. Mateyak, A. J. Obaya, and J. M. Sedivy (1999)
Mol. Cell. Biol. 19, 4672-4683
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Growth- and Cell Cycle-Regulated Protein, ASK, Activates Human Cdc7-Related Kinase and Is Essential for G1/S Transition in Mammalian Cells.

H. Kumagai, N. Sato, M. Yamada, D. Mahony, W. Seghezzi, E. Lees, K.-I. Arai, and H. Masai (1999)
Mol. Cell. Biol. 19, 5083-5095
 |  Abstract »  |  Full Text »  |  PDF »

Cdc20 associates with the kinase aurora2/Aik.

D. C. Farruggio, F. M. Townsley, and J. V. Ruderman (1999)
PNAS 96, 7306-7311
 |  Abstract »  |  Full Text »  |  PDF »

CDK inhibitors: positive and negative regulators of G1-phase progression.

C. J. Sherr and J. M. Roberts (1999)
Genes & Dev. 13, 1501-1512
 |  Full Text »

Hepatocyte Growth Factor Releases Mink Epithelial Cells from Transforming Growth Factor beta 1-Induced Growth Arrest by Restoring Cdk6 Expression and Cyclin E-Associated Cdk2 Activity.

M. Tsubari, J. Taipale, E. Tiihonen, J. Keski-Oja, and M. Laiho (1999)
Mol. Cell. Biol. 19, 3654-3663
 |  Abstract »  |  Full Text »  |  PDF »

Induction of p21WAF1/CIP1 and Inhibition of Cdk2 Mediated by the Tumor Suppressor p16INK4a.

J. Mitra, C. Y. Dai, K. Somasundaram, W. S. El-Deiry, K. Satyamoorthy, M. Herlyn, and G. H. Enders (1999)
Mol. Cell. Biol. 19, 3916-3928
 |  Abstract »  |  Full Text »  |  PDF »

Adenovirus-mediated Gene Transfer of MMAC1/PTEN to Glioblastoma Cells Inhibits S Phase Entry by the Recruitment of p27Kip1 into Cyclin E/CDK2 Complexes.

I. W. Cheney, S. T. C. Neuteboom, M.-T. Vaillancourt, M. Ramachandra, and R. Bookstein (1999)
Cancer Res. 59, 2318-2323
 |  Abstract »  |  Full Text »  |  PDF »

Correlation of GI Cyclins and Cyclin-Dependent Kinase Inhibitors Relative to Human Papillomavirus Infection in the Uterine Cervical Lesions.

N. H. Cho, H. J. Ahn, Y. T. Kim, and J. W. Kim (1999)
International Journal of Surgical Pathology 7, 61-71
 |  Abstract »  |  PDF »

Expression of EBNA-1 mRNA Is Regulated by Cell Cycle during Epstein-Barr Virus Type I Latency.

M. G. Davenport and J. S. Pagano (1999)
J. Virol. 73, 3154-3161
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin-dependent kinase control of centrosome duplication.

K. R. Lacey, P. K. Jackson, and T. Stearns (1999)
PNAS 96, 2817-2822
 |  Abstract »  |  Full Text »  |  PDF »

Cell Cycle Arrest during Measles Virus Infection: a G0-Like Block Leads to Suppression of Retinoblastoma Protein Expression.

D. Naniche, S. I. Reed, and M. B. A. Oldstone (1999)
J. Virol. 73, 1894-1901
 |  Abstract »  |  Full Text »  |  PDF »

Tumor Extension and Cell Proliferation in Adenocarcinomas of the Lung.

M. Shoji, Y. Dobashi, S. Morinaga, S.-X. Jiang, and T. Kameya (1999)
Am. J. Pathol. 154, 909-918
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin E Associates with BAF155 and BRG1, Components of the Mammalian SWI-SNF Complex, and Alters the Ability of BRG1 To Induce Growth Arrest.

F. Shanahan, W. Seghezzi, D. Parry, D. Mahony, and E. Lees (1999)
Mol. Cell. Biol. 19, 1460-1469
 |  Abstract »  |  Full Text »  |  PDF »

Forskolin Inhibits Cyclin D1 Expression in Cultured Airway Smooth-Muscle Cells.

N. L. Musa, M. Ramakrishnan, J. Li, S. Kartha, P. Liu, R. G. Pestell, and M. B. Hershenson (1999)
Am. J. Respir. Cell Mol. Biol. 20, 352-358
 |  Abstract »  |  Full Text »

Regulation of postembryonic G(1) cell cycle progression in Caenorhabditis elegans by a cyclin D/CDK-like complex.

M Park and M. Krause (1999)
Development 126, 4849-4860
 |  Abstract »  |  PDF »

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