Science 12 June 1992: Vol. 256. no. 5063, pp. 1550 - 1552 DOI: 10.1126/science.1317968

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Articles

A heterotypic bystander effect for tumor cell killing after adeno-associated virus/phage-mediated, vascular-targeted suicide gene transfer.

M. Trepel, C. A. Stoneham, H. Eleftherohorinou, N. D. Mazarakis, R. Pasqualini, W. Arap, and A. Hajitou (2009)
Mol. Cancer Ther. 8, 2383-2391
 |  Abstract »  |  Full Text »  |  PDF »

Directed evolution of an orthogonal nucleoside analog kinase via fluorescence-activated cell sorting.

L. Liu, Y. Li, D. Liotta, and S. Lutz (2009)
Nucleic Acids Res. 37, 4472-4481
 |  Abstract »  |  Full Text »  |  PDF »

Titration of Variant HSV1-tk Gene Expression to Determine the Sensitivity of 18F-FHBG PET Imaging in a Prostate Tumor.

M. Johnson, B. D.W. Karanikolas, S. J. Priceman, R. Powell, M. E. Black, H.-M. Wu, J. Czernin, S.-C. Huang, and L. Wu (2009)
J. Nucl. Med. 50, 757-764
 |  Abstract »  |  Full Text »  |  PDF »

Normal Brain Cells Contribute to the Bystander Effect in Suicide Gene Therapy of Malignant Glioma.

H. Miletic, Y. H. Fischer, T. Giroglou, M. A. Rueger, A. Winkeler, H. Li, U. Himmelreich, W. Stenzel, A. H. Jacobs, and D. von Laer (2007)
Clin. Cancer Res. 13, 6761-6768
 |  Abstract »  |  Full Text »  |  PDF »

Cationic Albumin-Conjugated Pegylated Nanoparticles Allow Gene Delivery into Brain Tumors via Intravenous Administration.

W. Lu, Q. Sun, J. Wan, Z. She, and X.-G. Jiang (2006)
Cancer Res. 66, 11878-11887
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Imaging with 123I-FIAU, 18F-FUdR, 18F-FET, and 18F-FDG for Monitoring Herpes Simplex Virus Type 1 Thymidine Kinase and Ganciclovir Prodrug Activation Gene Therapy of Cancer.

H.-E. Wang, H.-M. Yu, R.-S. Liu, M. Lin, J. G. Gelovani, J.-J. Hwang, H.-J. Wei, and W.-P. Deng (2006)
J. Nucl. Med. 47, 1161-1171
 |  Abstract »  |  Full Text »  |  PDF »

Hydroxyurea Induces Bystander Cytotoxicity in Cocultures of Herpes Simplex Virus Thymidine Kinase-Expressing and Nonexpressing HeLa Cells Incubated with Ganciclovir..

B. G. Gentry, P. D. Boucher, and D. S. Shewach (2006)
Cancer Res. 66, 3845-3851
 |  Abstract »  |  Full Text »  |  PDF »

Therapeutic protein transduction of mammalian cells and mice by nucleic acid-free lentiviral nanoparticles.

N. Link, C. Aubel, J. M. Kelm, R. R. Marty, D. Greber, V. Djonov, J. Bourhis, W. Weber, and M. Fussenegger (2006)
Nucleic Acids Res. 34, e16
 |  Abstract »  |  Full Text »  |  PDF »

Long-term Follow-up of Patients with Malignant Pleural Mesothelioma Receiving High-Dose Adenovirus Herpes Simplex Thymidine Kinase/Ganciclovir Suicide Gene Therapy.

D. H. Sterman, A. Recio, A. Vachani, J. Sun, L. Cheung, P. DeLong, K. M. Amin, L. A. Litzky, J. M. Wilson, L. R. Kaiser, et al. (2005)
Clin. Cancer Res. 11, 7444-7453
 |  Abstract »  |  Full Text »  |  PDF »

Gonadotropin-releasing hormone receptor-targeted gene therapy of gynecologic cancers.

C. Grundker, A. Huschmand Nia, and G. Emons (2005)
Mol. Cancer Ther. 4, 225-232
 |  Abstract »  |  Full Text »  |  PDF »

Inhibitory effect of recombinant adenovirus carrying melittin gene on hepatocellular carcinoma.

C.-Q. Ling, B. Li, C. Zhang, D.-Z. Zhu, X.-Q. Huang, W. Gu, and S.-X. Li (2005)
Ann. Onc. 16, 109-115
 |  Abstract »  |  Full Text »  |  PDF »

Efficacy and Safety Evaluation of Human Reovirus Type 3 in Immunocompetent Animals: Racine and Nonhuman Primates.

W. Q. Yang, X. Lun, C. A. Palmer, M. E. Wilcox, H. Muzik, Z. Q. Shi, R. Dyck, M. Coffey, B. Thompson, M. Hamilton, et al. (2004)
Clin. Cancer Res. 10, 8561-8576
 |  Abstract »  |  Full Text »  |  PDF »

Synthesis and Evaluation of 2'-Deoxy-2'-18F-Fluoro-5-Fluoro-1-{beta}-D-Arabinofuranosyluracil as a Potential PET Imaging Agent for Suicide Gene Expression.

M. M. Alauddin, A. Shahinian, R. Park, M. Tohme, J. D. Fissekis, and P. S. Conti (2004)
J. Nucl. Med. 45, 2063-2069
 |  Abstract »  |  Full Text »  |  PDF »

Potent Tumor-Specific Immunity Induced by an In vivo Heat Shock Protein-Suicide Gene-Based Tumor Vaccine.

W. Ren, R. Strube, X. Zhang, S.-Y. Chen, and X. F. Huang (2004)
Cancer Res. 64, 6645-6651
 |  Abstract »  |  Full Text »  |  PDF »

Structural Basis for Substrate Specificity of Escherichia coli Purine Nucleoside Phosphorylase.

E. M. Bennett, C. Li, P. W. Allan, W. B. Parker, and S. E. Ealick (2003)
J. Biol. Chem. 278, 47110-47118
 |  Abstract »  |  Full Text »  |  PDF »

Lipid-mediated Protein Delivery of Suicide Nucleoside Kinases.

X. Zheng, M. Lundberg, A. Karlsson, and M. Johansson (2003)
Cancer Res. 63, 6909-6913
 |  Abstract »  |  Full Text »  |  PDF »

A phase 3 trial of local chemotherapy with biodegradable carmustine (BCNU) wafers (Gliadel wafers) in patients with primary malignant glioma.

M. Westphal, D. C. Hilt, E. Bortey, P. Delavault, R. Olivares, P. C. Warnke, I. R. Whittle, J. Jaaskelainen, and Z. Ram (2003)
Neuro-oncol 5, 79-88
 |  Abstract »  |  PDF »

Expression of MRP4 Confers Resistance to Ganciclovir and Compromises Bystander Cell Killing.

M. Adachi, J. Sampath, L.-b. Lan, D. Sun, P. Hargrove, R. Flatley, A. Tatum, M. Z. Edwards, M. Wezeman, L. Matherly, et al. (2002)
J. Biol. Chem. 277, 38998-39004
 |  Abstract »  |  Full Text »  |  PDF »

Stable micro-dystrophin gene transfer using an integrating adeno-retroviral hybrid vector ameliorates the dystrophic pathology in mdx mouse muscle.

M. L. Roberts, D. J. Wells, I. R. Graham, S. A. Fabb, V. J. Hill, G. Duisit, K. Yuasa, S.'i. Takeda, F.-L. Cosset, and G. Dickson (2002)
Hum. Mol. Genet. 11, 1719-1730
 |  Abstract »  |  Full Text »  |  PDF »

Oncoretrovirus and Lentivirus Vectors Pseudotyped with Lymphocytic Choriomeningitis Virus Glycoprotein: Generation, Concentration, and Broad Host Range.

W. R. Beyer, M. Westphal, W. Ostertag, and D. von Laer (2002)
J. Virol. 76, 1488-1495
 |  Abstract »  |  Full Text »  |  PDF »

Influence of transfection with connexin 26 gene on malignant potential of human hepatoma cells.

A. Muramatsu, M. Iwai, T. Morikawa, S. Tanaka, T. Mori, Y. Harada, and T. Okanoue (2002)
Carcinogenesis 23, 351-358
 |  Abstract »  |  Full Text »  |  PDF »

Treatment of Malignant Gliomas with a Replicating Adenoviral Vector Expressing Herpes Simplex Virus-Thymidine Kinase.

D. Nanda, R. Vogels, M. Havenga, C. J. Avezaat, A. Bout, and P. S. Smitt (2001)
Cancer Res. 61, 8743-8750
 |  Abstract »  |  Full Text »  |  PDF »

Imaging Techniques for Gene Therapy: SPECT, PET, and MRI.

U. Haberkorn and A. Altmann (2001)
Journal of Pharmacy Practice 14, 383-396
 |  Abstract »  |  PDF »

Human glioma cells transformed by IGF-I triple helix technology show immune and apoptotic characteristics determining cell selection for gene therapy of glioblastoma.

A Ly, H T Duc, M Kalamarides, L A Trojan, Y Pan, A Shevelev, J-C Francois, T Noel, A Kane, D Henin, et al. (2001)
Mol. Pathol. 54, 230-239
 |  Abstract »  |  Full Text »  |  PDF »

Bystander Effects of Cancer Cell Lines Transduced with the Multisubstrate Deoxyribonucleoside Kinase of Drosophila melanogaster and Synergistic Enhancement by Hydroxyurea.

X. Zheng, M. Johansson, and A. Karlsson (2001)
Mol. Pharmacol. 60, 262-266
 |  Abstract »  |  Full Text »  |  PDF »

Reovirus as an Oncolytic Agent Against Experimental Human Malignant Gliomas.

M. E. Wilcox, W. Yang, D. Senger, N. B. Rewcastle, D. G. Morris, P. M. A. Brasher, Z. Q. Shi, R. N. Johnston, S. Nishikawa, P. W. K. Lee, et al. (2001)
J Natl Cancer Inst 93, 903-912
 |  Abstract »  |  Full Text »  |  PDF »

Engineering of Macrophages to Produce IFN-{{gamma}} in Response to Hypoxia.

L. Carta, S. Pastorino, G. Melillo, M. C. Bosco, S. Massazza, and L. Varesio (2001)
J. Immunol. 166, 5374-5380
 |  Abstract »  |  Full Text »  |  PDF »

Selective Abolishment of Pyrimidine Nucleoside Kinase Activity of Herpes Simplex Virus Type 1 Thymidine Kinase by Mutation of Alanine-167 to Tyrosine.

B. Degrève, R. Esnouf, E. De Clercq, and J. Balzarini (2001)
Mol. Pharmacol. 58, 1326-1332
 |  Abstract »  |  Full Text »

Potential of gene therapy for brain tumors.

P. Y.P. Lam and X. O. Breakefield (2001)
Hum. Mol. Genet. 10, 777-787
 |  Abstract »  |  Full Text »  |  PDF »

Positron Emission Tomography-based Imaging of Transgene Expression Mediated by Replication-conditional, Oncolytic Herpes Simplex Virus Type 1 Mutant Vectors in Vivo.

A. Jacobs, J. G. Tjuvajev, M. Dubrovin, T. Akhurst, J. Balatoni, B. Beattie, R. Joshi, R. Finn, S. M. Larson, U. Herrlinger, et al. (2001)
Cancer Res. 61, 2983-2995
 |  Abstract »  |  Full Text »

Antiviral Guanosine Analogs as Substrates for Deoxyguanosine Kinase: Implications for Chemotherapy.

A. H. Sjöberg, L. Wang, and S. Eriksson (2001)
Antimicrob. Agents Chemother. 45, 739-742
 |  Abstract »  |  Full Text »

Mutation of Gln125 to Asn Selectively Abolishes the Thymidylate Kinase Activity of Herpes Simplex Virus Type 1 Thymidine Kinase.

B. Degrève, R. Esnouf, E. De Clercq, and J. Balzarini (2001)
Mol. Pharmacol. 59, 285-293
 |  Abstract »  |  Full Text »

A TVA-Single-Chain Antibody Fusion Protein Mediates Specific Targeting of a Subgroup A Avian Leukosis Virus Vector to Cells Expressing a Tumor-Specific Form of Epidermal Growth Factor Receptor.

S. Snitkovsky, T. M. J. Niederman, B. S. Carter, R. C. Mulligan, and J. A. T. Young (2000)
J. Virol. 74, 9540-9545
 |  Abstract »  |  Full Text »

Combined suicide and cytokine gene therapy for peritoneal carcinomatosis.

C Lechanteur, P Delvenne, F Princen, M Lopez, G Fillet, J Gielen, M-P Merville, and V Bours (2000)
Gut 47, 343-348
 |  Abstract »  |  Full Text »  |  PDF »

Thrombasthenic mice generated by replacement of the integrin alpha IIb gene: demonstration that transcriptional activation of this megakaryocytic locus precedes lineage commitment.

D. T.-L. Roux, V. Roullot, C. Poujol, T. Kortulewski, P. Nurden, and G. Marguerie (2000)
Blood 96, 1399-1408
 |  Abstract »  |  Full Text »  |  PDF »

Bystander Effect in Herpes Simplex Virus-Thymidine Kinase/Ganciclovir Cancer Gene Therapy: Role of Gap-junctional Intercellular Communication1.

M. Mesnil and H. Yamasaki (2000)
Cancer Res. 60, 3989-3999
 |  Abstract »  |  Full Text »

Impact of genomics on drug discovery and clinical medicine.

G. Emilien, M. Ponchon, C. Caldas, O. Isacson, and J.-M. Maloteaux (2000)
QJM 93, 391-423
 |  Abstract »  |  Full Text »  |  PDF »

Glioblastoma multiforme: The terminator.

E. C. Holland (2000)
PNAS 97, 6242-6244
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Intergeneric poliovirus recombinants for the treatment of malignant glioma.

M. Gromeier, S. Lachmann, M. R. Rosenfeld, P. H. Gutin, and E. Wimmer (2000)
PNAS 97, 6803-6808
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of Tissue Chimerism in Nude Mouse Brain and Abdominal Xenograft Models of Human Glioblastoma Multiforme: What Does It Tell Us About the Models and About Glioblastoma Biology and Therapy?.

L. Antunes, K. S. Angioi–Duprez, S. R. Bracard, N. A. Klein–Monhoven, A. E. Le Faou, A. M. Duprez, and F. M. Plénat (2000)
J. Histochem. Cytochem. 48, 847-858
 |  Abstract »  |  Full Text »

Inhibition of Angiogenesis and Induction of Apoptosis Are Involved in E1A-mediated Bystander Effect and Tumor Suppression.

R. Shao, W. Xia, and M.-C. Hung (2000)
Cancer Res. 60, 3123-3126
 |  Abstract »  |  Full Text »

Cancer Gene Therapy by Thyroid Hormone-mediated Expression of Toxin Genes.

V. Martín, M. L. Cortés, Pablo de Felipe, A. Farsetti, N. B. Calcaterra, and M. Izquierdo (2000)
Cancer Res. 60, 3218-3224
 |  Abstract »  |  Full Text »

Transactivation of the Metallothionein Promoter in Cisplatin-Resistant Cancer Cells: a Specific Gene Therapy Strategy.

D. Vandier, V. Calvez, L. Massade, A. Gouyette, L. Mickley, T. Fojo, and O. Rixe (2000)
J Natl Cancer Inst 92, 642-647
 |  Abstract »  |  Full Text »  |  PDF »

Gene Transfer into Brain Parenchyma Elicits Antitumor Effects.

H. M. Fathallah-Shaykh, A. I. Kafrouni, L.-J. Zhao, G. M. Smith, and J. Forman (2000)
Cancer Res. 60, 1797-1799
 |  Abstract »  |  Full Text »

Cytogenetic genotoxicity of anti-herpes purine nucleoside analogues in CHO cells expressing the thymidine kinase gene of herpes simplex virus type 1: comparison of ganciclovir, penciclovir and aciclovir.

R. Thust, M. Tomicic, R. Klocking, P. Wutzler, and B. Kaina (2000)
Mutagenesis 15, 177-184
 |  Abstract »  |  Full Text »  |  PDF »

An oncolytic herpes simplex virus type 1 selectively destroys diffuse liver metastases from colon carcinoma.

S. S. YOON, H. NAKAMURA, N. M. CARROLL, B. P. BODE, E. A. CHIOCCA, and K. K. TANABE (2000)
FASEB J 14, 301-311
 |  Abstract »  |  Full Text »

Cellular Suicide Therapy of Malignant Disease.

C. J. Link, T. Seregina, A. Traynor, and R. K. Burt (2000)
Oncologist 5, 68-74
 |  Abstract »  |  Full Text »

Differential Ganciclovir-mediated Cell Killing by Glutamine 125 Mutants of Herpes Simplex Virus Type 1 Thymidine Kinase.

R. R. Drake, T. N. Wilbert, T. A. Hinds, and K. M. Gilbert (1999)
J. Biol. Chem. 274, 37186-37192
 |  Abstract »  |  Full Text »  |  PDF »

Single-Step Conversion of Cells to Retrovirus Vector Producers with Herpes Simplex Virus-Epstein-Barr Virus Hybrid Amplicons.

M. Sena-Esteves, Y. Saeki, S. M. Camp, E. A. Chiocca, and X. O. Breakefield (1999)
J. Virol. 73, 10426-10439
 |  Abstract »  |  Full Text »

A Cell Type-specific and Gap Junction-independent Mechanism for the Herpes Simplex Virus-1 Thymidine Kinase Gene/Ganciclovir-mediated Bystander Effect.

F. Princen, P. Robe, C. Lechanteur, M. Mesnil, J.-M. Rigo, J. Gielen, M.-P. Merville, and V. Bours (1999)
Clin. Cancer Res. 5, 3639-3644
 |  Abstract »  |  Full Text »  |  PDF »

X-Ray Irradiation Induces Thymidine Phosphorylase and Enhances the Efficacy of Capecitabine (Xeloda) in Human Cancer Xenografts.

N. Sawada, T. Ishikawa, F. Sekiguchi, Y. Tanaka, and H. Ishitsuka (1999)
Clin. Cancer Res. 5, 2948-2953
 |  Abstract »  |  Full Text »  |  PDF »

Cloning and Characterization of the Multisubstrate Deoxyribonucleoside Kinase of Drosophila melanogaster.

M. Johansson, A. R. Van Rompay, B. Degreve, J. Balzarini, and A. Karlsson (1999)
J. Biol. Chem. 274, 23814-23819
 |  Abstract »  |  Full Text »  |  PDF »

Herpes simplex virus thymidine kinase/ganciclovir-induced apoptosis involves ligand-independent death receptor aggregation and activation of caspases.

C. Beltinger, S. Fulda, T. Kammertoens, E. Meyer, W. Uckert, and K.-M. Debatin (1999)
PNAS 96, 8699-8704
 |  Abstract »  |  Full Text »  |  PDF »

Ionizing Radiation Improves Survival in Mice Bearing Intracranial High-Grade Gliomas Injected with Genetically Modified Herpes Simplex Virus.

J. D. Bradley, Y. Kataoka, S. Advani, S. M. Chung, R. B. Arani, G. Y. Gillespie, R. J. Whitley, J. M. Markert, B. Roizman, and R. R. Weichselbaum (1999)
Clin. Cancer Res. 5, 1517-1522
 |  Abstract »  |  Full Text »  |  PDF »

Vesicular Stomatitis Virus G Pseudotyped Retrovector Mediates Effective in Vivo Suicide Gene Delivery in Experimental Brain Cancer.

J. Galipeau, H. Li, A. Paquin, F. Sicilia, G. Karpati, and J. Nalbantoglu (1999)
Cancer Res. 59, 2384-2394
 |  Abstract »  |  Full Text »  |  PDF »

Current Therapy for Brain Tumors: Back to the Future.

W. R. Shapiro (1999)
Arch Neurol 56, 429-432
 |  Abstract »  |  Full Text »  |  PDF »

New Molecular Strategies to Cure Brain Tumors.

H. Fathallah-Shaykh (1999)
Arch Neurol 56, 449-453
 |  Abstract »  |  Full Text »  |  PDF »

Comparison of Activation of CPT-11 by Rabbit and Human Carboxylesterases for Use in Enzyme/Prodrug Therapy.

M. K. Danks, C. L. Morton, E. J. Krull, P. J. Cheshire, L. B. Richmond, C. W. Naeve, C. A. Pawlik, P. J. Houghton, and P. M. Potter (1999)
Clin. Cancer Res. 5, 917-924
 |  Abstract »  |  Full Text »  |  PDF »

Cancer gene therapy update.

J. A Smith and B. R Goldspiel (1999)
Journal of Oncology Pharmacy Practice 5, 7-21
 |  Abstract »  |  PDF »

Eradication of Rat Malignant Gliomas by Retroviral-mediated, in Vivo Delivery of the Interleukin 4 Gene.

S. Benedetti, M. G. Bruzzone, B. Pollo, F. DiMeco, L. Magrassi, B. Pirola, N. Cirenei, M. P. Colombo, and G. Finocchiaro (1999)
Cancer Res. 59, 645-652
 |  Abstract »  |  Full Text »  |  PDF »

Cytotoxicity and Accumulation of Ganciclovir Triphosphate in Bystander Cells Cocultured with Herpes Simplex Virus Type 1 Thymidine Kinase-expressing Human Glioblastoma Cells.

L. Z. Rubsam, P. D. Boucher, P. J. Murphy, M. KuKuruga, and D. S. Shewach (1999)
Cancer Res. 59, 669-675
 |  Abstract »  |  Full Text »  |  PDF »

Therapy of Colon Cancer with Oncolytic Adenovirus Is Enhanced by the Addition of Herpes Simplex Virus-thymidine kinase.

O. Wildner, R. M. Blaese, and J. C. Morris (1999)
Cancer Res. 59, 410-413
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-beta gene therapy inhibits tumor formation and causes regression of established tumors in immune-deficient mice.

X.-Q. Qin, N. Tao, A. Dergay, P. Moy, S. Fawell, A. Davis, J. M. Wilson, and J. Barsoum (1998)
PNAS 95, 14411-14416
 |  Abstract »  |  Full Text »  |  PDF »

Combination Gene Delivery of the Cell Cycle Inhibitor p27 with Thymidine Kinase Enhances Prodrug Cytotoxicity.

X. Danthinne, K. Aoki, A. L. Kurachi, G. J. Nabel, and E. G. Nabel (1998)
J. Virol. 72, 9201-9207
 |  Abstract »  |  Full Text »  |  PDF »

Synthetic activation of caspases: Artificial death switches.

R. A. MacCorkle, K. W. Freeman, and D. M. Spencer (1998)
PNAS 95, 3655-3660
 |  Abstract »  |  Full Text »  |  PDF »

Bystander Tumoricidal Effect and Gap Junctional Communication in Lung Cancer Cell Lines.

K. Imaizumi, Y. Hasegawa, T. Kawabe, N. Emi, H. Saito, K. Naruse, and K. Shimokata (1998)
Am. J. Respir. Cell Mol. Biol. 18, 205-212
 |  Abstract »  |  Full Text »

Gene Therapy for Infectious Diseases.

B. A. Bunnell and R. A. Morgan (1998)
Clin. Microbiol. Rev. 11, 42-56
 |  Abstract »  |  Full Text »  |  PDF »

Tissue-specific expression of herpes simplex virus thymidine kinase gene delivered by adeno-associated virus inhibits the growth of human hepatocellular carcinoma in athymic mice.

H. Su, R. Lu, J. C. Chang, and Y. W. Kan (1997)
PNAS 94, 13891-13896
 |  Abstract »  |  Full Text »  |  PDF »

Apoptosis in neural development and disease.

N. D Mazarakis, A D. Edwards, and H. Mehmet (1997)
Arch. Dis. Child. Fetal Neonatal Ed. 77, 165F-170
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A 2.7-kb Portion of the 5' Flanking Region of the Murine Glycoprotein alpha IIb Gene Is Transcriptionally Active in Primitive Hematopoietic Progenitor Cells.

P. Tropel, V. Roullot, M. Vernet, C. Poujol, H. Pointu, P. Nurden, G. Marguerie, and D. Tronik-Le Roux (1997)
Blood 90, 2995-3004
 |  Abstract »  |  Full Text »  |  PDF »

Liposome mediated gene transfer into the rat oesophagus.

R M Schmid, H Weidenbach, G F Draenert, S Liptay, H Luhrs, and G Adler (1997)
Gut 41, 549-556
 |  Abstract »  |  Full Text »  |  PDF »

Reduction of Restenosis After Angioplasty in an Atheromatous Rabbit Model by Suicide Gene Therapy.

P. G. Steg, O. Tahlil, N. Aubailly, J.-M. Caillaud, J.-F. Dedieu, K. Berthelot, A. Le Roux, L. Feldman, M. Perricaudet, P. Denefle, et al. (1997)
Circulation 96, 408-411
 |  Abstract »  |  Full Text »

Amphotropic murine leukemia viruses induce spongiform encephalomyelopathy.

C. Munk, J. Lohler, V. Prassolov, U. Just, M. Stockschlader, and C. Stocking (1997)
PNAS 94, 5837-5842
 |  Abstract »  |  Full Text »  |  PDF »

Gene Transfer to Cerebral Blood Vessels After Subarachnoid Hemorrhage.

M. G. Muhonen, H. Ooboshi, M. J. Welsh, B. L. Davidson, and D. D. Heistad (1997)
Stroke 28, 822-829
 |  Abstract »  |  Full Text »

Topical Review: Gene Therapy for Neurologic Disease: Benchtop Discoveries to Bedside Applications. 1. The Bench.

B. L. Maria, C. D. Medina, K. B.N. Hoang, and M. I. Phillips (1997)
J Child Neurol 12, 1-12
 |  Abstract »  |  PDF »

Graded Sonic Hedgehog Signaling and the Specification of Cell Fate in the Ventral Neural Tube.

J. Ericson, J. Briscoe, P. Rashbass, V. van Heyningen, and T.M. Jessell (1997)
Cold Spring Harb Symp Quant Biol 62, 451-466
 |  Abstract »  |  PDF »

A Novel Herpes Vector for the High-Efficiency Transduction of Normal and Malignant Human Hematopoietic Cells.

D. Dilloo, D. Rill, C. Entwistle, M. Boursnell, W. Zhong, W. Holden, M. Holladay, S. Inglis, and M. Brenner (1997)
Blood 89, 119-127
 |  Abstract »  |  Full Text »  |  PDF »

Conditional Ablation of Cerebellar Astrocytes in Postnatal Transgenic Mice.

C. L. Delaney, M. Brenner, and A. Messing (1996)
J. Neurosci. 16, 6908-6918
 |  Abstract »  |  Full Text »  |  PDF »

HSV-tk Gene Therapy in Head and Neck Squamous Cell Carcinoma: Enhancement by the Local and Distant Bystander Effect.

K. M. Wilson, P. J. Stambrook, W. L. Bi, Z. P. Pavelic, L. Pavelic, and J. L. Gluckman (1996)
Arch Otolaryngol Head Neck Surg 122, 746-749
 |  Abstract »  |  PDF »

Gene therapy for vascular smooth muscle cell proliferation after arterial injury.

T Ohno, D Gordon, H San, V. Pompili, M. Imperiale, G. Nabel, and E. Nabel (1994)
Science 265, 781-784
 |  Abstract »  |  PDF »

Neurological Surgery.

R. H. Wilkins (1994)
JAMA 271, 1684-1685
 |  Abstract »  |  PDF »

Current Issues in Cancer: Genes dreams and cancer.

K Sikora (1994)
BMJ 308, 1217-1221
 |  Full Text »

Toxicity and Immunologic Effects of In Vivo Retrovirus-mediated Gene Transfer of the Herpes Simplex-Thymidine Kinase Gene into Solid Tumors.

K.W. Culver, D.W. Moorman, R.R. Muldoon, R.M. Paulsen Jr., J.L. Lamsam, H.W. Walling, and C.J. Link Jr. (1994)
Cold Spring Harb Symp Quant Biol 59, 685-690
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