Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 8 May 1992:
Vol. 256. no. 5058, pp. 833 - 836
DOI: 10.1126/science.256.5058.833
Prev | Table of Contents | Next

Articles

Science, Vol 256, Issue 5058, 833-836
Copyright © 1992 by American Association for the Advancement of Science

articles

Changes in the sensory processing of olfactory signals induced by birth in sleep

KM Kendrick, F Levy, and EB Keverne

Agricultural and Food Research Council, Institute of Animal Physiology and Genetics Research, Babraham, Cambridge, United Kingdom.

After giving birth, sheep and many other species form a selective bond with their offspring based on the sense of smell. Processing of olfactory signals is altered to allow the animals to perform this selective recognition. Lamb odors have little effect on either neurotransmitter release or electrical activity of neurons in the olfactory bulb before birth. However, after birth there is an increase in the number of mitral cells, the principal cells of the olfactory bulb, that respond to lamb odors, which is associated with increased cholinergic and noradrenergic neurotransmitter release. Selective recognition of lambs is accompanied by increased activity of a subset of mitral cells and release of glutamate and gamma-aminobutyric acid (GABA) from the dendrodendritic synapses between the mitral and granule cells. The relation between the release of each transmitter after birth also suggests an increased efficacy of glutamate-evoked GABA release.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Odor Perception and Olfactory Bulb Plasticity in Adult Mammals.
N. Mandairon and C. Linster (2009)
J Neurophysiol 101, 2204-2209
   Abstract »    Full Text »    PDF »
Noradrenergic Induction of Odor-Specific Neural Habituation and Olfactory Memories.
S. D. Shea, L. C. Katz, and R. Mooney (2008)
J. Neurosci. 28, 10711-10719
   Abstract »    Full Text »    PDF »
Neurobiology of a Simple Memory.
D. A. Wilson and C. Linster (2008)
J Neurophysiol 100, 2-7
   Abstract »    Full Text »    PDF »
Distinct neural mechanisms mediate olfactory memory formation at different timescales.
A. M. McNamara, P. D. Magidson, C. Linster, D. A. Wilson, and T. A. Cleland (2008)
Learn. Mem. 15, 117-125
   Abstract »    Full Text »    PDF »
Octopamine-Mediated Neuronal Plasticity in Honeybees: Implications for Olfactory Dysfunction in Humans.
T. Farooqui (2007)
Neuroscientist 13, 304-322
   Abstract »    PDF »
Mammalian social odours: attraction and individual recognition.
P. A Brennan and K. M Kendrick (2006)
Phil Trans R Soc B 361, 2061-2078
   Abstract »    Full Text »    PDF »
Mother-infant bonding and the evolution of mammalian social relationships.
K.D Broad, J.P Curley, and E.B Keverne (2006)
Phil Trans R Soc B 361, 2199-2214
   Abstract »    Full Text »    PDF »
Importance of Learning in the Response of Ewes to Male Odor.
H. Gelez, E. Archer, D. Chesneau, R. Campan, and C. Fabre-Nys (2004)
Chem Senses 29, 555-563
   Abstract »    Full Text »    PDF »
Inhibitory Interneurons in the Olfactory Bulb: From Development to Function.
P.-M. Lledo, A. Saghatelyan, and M. Lemasson (2004)
Neuroscientist 10, 292-303
   Abstract »    PDF »
Learning modulates the ensemble representations for odors in primary olfactory networks.
K. C. Daly, T. A. Christensen, H. Lei, B. H. Smith, and J. G. Hildebrand (2004)
PNAS 101, 10476-10481
   Abstract »    Full Text »    PDF »
Acetylcholine and Olfactory Perceptual Learning.
D. A. Wilson, M. L. Fletcher, and R. M. Sullivan (2004)
Learn. Mem. 11, 28-34
   Abstract »    Full Text »    PDF »
Mechanisms of Lateral Inhibition in the Olfactory Bulb: Efficiency and Modulation of Spike-Evoked Calcium Influx into Granule Cells.
V. Egger, K. Svoboda, and Z. F. Mainen (2003)
J. Neurosci. 23, 7551-7558
   Abstract »    Full Text »    PDF »
Olfactory Bulb Mitral-Tufted Cell Plasticity: Odorant-Specific Tuning Reflects Previous Odorant Exposure.
M. L. Fletcher and D. A. Wilson (2003)
J. Neurosci. 23, 6946-6955
   Abstract »    Full Text »    PDF »
Modulation of Early Olfactory Processing by an Octopaminergic Reinforcement Pathway in the Honeybee.
T. Farooqui, K. Robinson, H. Vaessin, and B. H. Smith (2003)
J. Neurosci. 23, 5370-5380
   Abstract »    Full Text »    PDF »
Early Odor Preference Learning in the Rat: Bidirectional Effects of cAMP Response Element-Binding Protein (CREB) and Mutant CREB Support a Causal Role for Phosphorylated CREB.
Q. Yuan, C. W. Harley, A. Darby-King, R. L. Neve, and J. H. McLean (2003)
J. Neurosci. 23, 4760-4765
   Abstract »    Full Text »    PDF »
The DAF-7 TGF-beta signaling pathway regulates chemosensory receptor gene expression in C. elegans.
K. M. Nolan, T. R. Sarafi-Reinach, J. G. Horne, A. M. Saffer, and P. Sengupta (2002)
Genes & Dev. 16, 3061-3073
   Abstract »    Full Text »    PDF »
Exposure to Behaviourally Relevant Odour Reveals Differential Characteristics in Rat Central Olfactory Pathways as Studied through Oscillatory Activities.
P. Chabaud, N. Ravel, D.A. Wilson, A.M. Mouly, M. Vigouroux, V. Farget, and R. Gervais (2000)
Chem Senses 25, 561-573
   Abstract »    Full Text »    PDF »
Activity-Dependent Changes to the Brain and Behavior of the Honey Bee, Apis mellifera (L.).
D. Sigg, C. M. Thompson, and A. R. Mercer (1997)
J. Neurosci. 17, 7148-7156
   Abstract »    Full Text »    PDF »
Environmental signals modulate olfactory acuity, discrimination, and memory in Caenorhabditis elegans..
H A Colbert and C I Bargmann (1997)
Learn. Mem. 4, 179-191
   Abstract »    PDF »
Activation of Locus Coeruleus Enhances the Responses of Olfactory Bulb Mitral Cells to Weak Olfactory Nerve Input.
M. Jiang, E. R. Griff, M. Ennis, L. A. Zimmer, and M. T. Shipley (1996)
J. Neurosci. 16, 6319-6329
   Abstract »    Full Text »    PDF »
Psychopharmacology of maternal behaviour.
E.B. Keverne (1996)
J Psychopharmacol 10, 16-22
   PDF »
Experience Modifies Olfactory Acuity: Acetylcholine-Dependent Learning Decreases Behavioral Generalization between Similar Odorants.
M. L. Fletcher and D. A. Wilson (2002)
J. Neurosci. 22, RC201
   Abstract »    Full Text »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)