Science 8 May 1992: Vol. 256. no. 5058, pp. 808 - 813 DOI: 10.1126/science.256.5058.808

Prev | Table of Contents | Next

Articles

Gene therapy in clinical medicine.

S M Selkirk (2004)
Postgrad. Med. J. 80, 560-570
 |  Abstract »  |  Full Text »  |  PDF »

Gene Transfer of Human Hepatocyte Growth Factor into Rat Skin Wounds Mediated by Liposomes Coated with the Sendai Virus (Hemagglutinating Virus of Japan).

K. Nakanishi, M. Uenoyama, N. Tomita, R. Morishita, Y. Kaneda, T. Ogihara, K. Matsumoto, T. Nakamura, A. Maruta, S. Matsuyama, et al. (2002)
Am. J. Pathol. 161, 1761-1772
 |  Abstract »  |  Full Text »  |  PDF »

Gene Therapy in Orthopaedic Surgery.

D. Hannallah, B. Peterson, J. R. Lieberman, F. H. Fu, and J. Huard (2002)
J. Bone Joint Surg. Am. 84, 1046-1061
 |  Full Text »

Molecular Imaging and Gene Therapy.

C. Nichol and E. E. Kim (2001)
J. Nucl. Med. 42, 1368-1374
 |  Abstract »  |  Full Text »  |  PDF »

Gene Transfer of Heat-Shock Protein 70 Reduces Infarct Size In Vivo After Ischemia/Reperfusion in the Rabbit Heart.

S. Okubo, O. Wildner, M. R. Shah, J. C. Chelliah, M. L. Hess, and R. C. Kukreja (2001)
Circulation 103, 877-881
 |  Abstract »  |  Full Text »  |  PDF »

Percutaneous in vivo gene transfer to the peripheral lungs using plasmid-liposome complexes.

H. Saito, H. Nakamura, S. Kato, S. Inoue, M. Inage, M. Ito, and H. Tomoike (2000)
Am J Physiol Lung Cell Mol Physiol 279, L651-L657
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Herpes Simplex Virus ICP47 and Human Cytomegalovirus US11 Prevents Recognition of Transgene Products by CD8+ Cytotoxic T Lymphocytes.

C. Berger, S. Xuereb, D. C. Johnson, K. S. Watanabe, H.-P. Kiem, P. D. Greenberg, and S. R. Riddell (2000)
J. Virol. 74, 4465-4473
 |  Abstract »  |  Full Text »

Gene Therapy for Lung Disease: Hype or Hope?.

S. M. Albelda, R. Wiewrodt, and J. B. Zuckerman (2000)
Ann Intern Med 132, 649-660
 |  Abstract »  |  Full Text »  |  PDF »

Focal angiogen therapy using intramyocardial delivery of an adenovirus vector coding for vascular endothelial growth factor 121.

L. Y. Lee, S. R. Patel, N. R. Hackett, C. A. Mack, D. R. Polce, T. El-Sawy, R. Hachamovitch, P. Zanzonico, T. A. Sanborn, M. Parikh, et al. (2000)
Ann. Thorac. Surg. 69, 14-23
 |  Abstract »  |  Full Text »  |  PDF »

Mutations in the Retinoblastoma-related Gene RB2/p130 in Lung Tumors and Suppression of Tumor Growth in Vivo by Retrovirus-mediated Gene Transfer.

P. P. Claudio, C. M. Howard, C. Pacilio, C. Cinti, G. Romano, C. Minimo, N. M. Maraldi, J. D. Minna, L. Gelbert, L. Leoncini, et al. (2000)
Cancer Res. 60, 372-382
 |  Abstract »  |  Full Text »

Prospects for in Utero Human Gene Therapy.

E. D. Zanjani and W. F. Anderson (1999)
Science 285, 2084-2088
 |  Abstract »  |  Full Text »

Highly efficient liposome-mediated gene transfer of inducible nitric oxide synthase in vivo and in vitro in vascular smooth muscle cells.

K. Veit, J.-P. Boissel, M. Buerke, T. Grosser, J. Meyer, and H. Darius (1999)
Cardiovasc Res 43, 808-822
 |  Abstract »  |  Full Text »  |  PDF »

EXOGENOUS CONTROL OF CARDIAC GENE THERAPY: EVIDENCE OF REGULATED MYOCARDIAL TRANSGENE EXPRESSION AFTER ADENOVIRUS AND ADENO-ASSOCIATED VIRUS TRANSFER OF EXPRESSION CASSETTES CONTAINING CORTICOSTEROID RESPONSE ELEMENT PROMOTERS.

L. Y. Lee, X. Zhou, D. R. Polce, T. El-Sawy, S. R. Patel, G. D. Thakker, K. Narumi, R. G. Crystal, and T. K. Rosengart (1999)
J. Thorac. Cardiovasc. Surg. 118, 26-25
 |  Abstract »  |  Full Text »  |  PDF »

Molecular advances in cardiac and cardiovascular disease.

A. Basile-Borgia, J. H Abel, and H. Mahloogi (1999)
Perfusion 14, 89-99
 |  Abstract »  |  PDF »

Site-Specific Integration in Mammalian Cells Mediated by a New Hybrid Baculovirus-Adeno-Associated Virus Vector.

F. Palombo, A. Monciotti, A. Recchia, R. Cortese, G. Ciliberto, and N. La Monica (1998)
J. Virol. 72, 5025-5034
 |  Abstract »  |  Full Text »  |  PDF »

Delayed Targeting of Cytokine-Nonresponsive Human Bone Marrow CD34+ Cells With Retrovirus-Mediated Gene Transfer Enhances Transduction Efficiency and Long-Term Expression of Transduced Genes.

P. Veena, C. M. Traycoff, D. A. Williams, J. McMahel, S. Rice, K. Cornetta, and E. F. Srour (1998)
Blood 91, 3693-3701
 |  Abstract »  |  Full Text »  |  PDF »

Gene Therapy for Infectious Diseases.

B. A. Bunnell and R. A. Morgan (1998)
Clin. Microbiol. Rev. 11, 42-56
 |  Abstract »  |  Full Text »  |  PDF »

Severe Combined Immunodeficiency Mice Engrafted With Human T Cells, B Cells, and Myeloid Cells After Transplantation With Human Fetal Bone Marrow or Liver Cells and Implanted With Human Fetal Thymus: A Model for Studying Human Gene Therapy.

S. Yurasov, T. R. Kollmann, A. Kim, C. A. Raker, M. Hachamovitch, F. Wong-Staal, and H. Goldstein (1997)
Blood 89, 1800-1810
 |  Abstract »  |  Full Text »  |  PDF »

Novel pyridinium surfactants for efficient, nontoxic in vitro gene delivery.

I. van der Woude, A. Wagenaar, A. A. P. Meekel, M. B. A. ter Beest, M. H. J. Ruiters, J. B. F. N. Engberts, and D. Hoekstra (1997)
PNAS 94, 1160-1165
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Herpes Vector for the High-Efficiency Transduction of Normal and Malignant Human Hematopoietic Cells.

D. Dilloo, D. Rill, C. Entwistle, M. Boursnell, W. Zhong, W. Holden, M. Holladay, S. Inglis, and M. Brenner (1997)
Blood 89, 119-127
 |  Abstract »  |  Full Text »  |  PDF »

Avoidance of Immune Response Prolongs Expression of Genes Delivered to the Adult Rat Myocardium by Replication-Defective Adenovirus.

M. J. Quinones, J. Leor, R. A. Kloner, M. Ito, M. Patterson, W. F. Witke, and L. Kedes (1996)
Circulation 94, 1394-1401
 |  Abstract »  |  Full Text »

Molecular Biology in Ophthalmology: A Review of Principles and Recent Advances.

N. G. Della (1996)
Arch Ophthalmol 114, 457-463
 |  Abstract »  |  PDF »

Keratinocyte Gene Transfer and Gene Therapy.

J.A. Garlick and E.S. Fenjves (1996)
Critical Reviews in Oral Biology & Medicine 7, 204-221
 |  Abstract »  |  Full Text »  |  PDF »

Heterogeneity of Adenovirus-Mediated Gene Transfer in Cultured Thoracic Aorta and Renal Artery of Rats.

A. Yao and D. H. Wang (1995)
Hypertension 26, 1046-1050
 |  Abstract »  |  Full Text »

Gene Therapy in Peripheral Blood Lymphocytes and Bone Marrow for ADA- Immunodeficient Patients.

C. Bordignon, L. D. Notarangelo, N. Nobili, G. Ferrari, G. Casorati, P. Panina, E. Mazzolari, D. Maggioni, C. Rossi, P. Servida, et al. (1995)
Science 270, 470-475
 |  Abstract »  |  PDF »

Innovation in the pharmaceutical industry.

R Sykes (1994)
BMJ 309, 422-3
 |  Full Text »

Gene Transfer and Bone Marrow Transplantation.

M.K. Brenner, H.E. Heslop, D. Rill, C. Li, T. Nilson, M. Roberts, C. Smith, R. Krance, and C. Rooney (1994)
Cold Spring Harb Symp Quant Biol 59, 691-697
 |  Abstract »  |  PDF »

Progress Toward Human Gene Therapy.

M. A. Morsy, K. Mitani, P. Clemens, and C. T. Caskey (1993)
JAMA 270, 2338-2345
 |  Abstract »  |  PDF »

Medical Genetics: A 40-Year Perspective on the Evolution of a Medical Specialty From a Basic Science.

V. A. McKusick (1993)
JAMA 270, 2351-2356
 |  Abstract »  |  PDF »

Gene Therapy for Neurologic Disease.

S. T. Suhr and F. H. Gage (1993)
Arch Neurol 50, 1252-1268
 |  Abstract »  |  PDF »

Keratinocyte Gene Therapy.

J. C. Vogel (1993)
Arch Dermatol 129, 1478-1483
 |  Abstract »  |  PDF »

Ocular Gene Therapy: From Fantasy to Foreseeable Reality.

D. J. Zack (1993)
Arch Ophthalmol 111, 1477-1479
 |  Abstract »  |  PDF »

Somatic Gene Therapy in Otolaryngology--Head and Neck Surgery.

B. W. O'Malley Jr and F. D. Ledley (1993)
Arch Otolaryngol Head Neck Surg 119, 1191-1197
 |  Abstract »  |  PDF »

Regulation of Somatic-Cell Therapy and Gene Therapy by the Food and Drug Administration.

D. A. Kessler, J. P. Siegel, P. D. Noguchi, K. C. Zoon, K. L. Feiden, and J. Woodcock (1993)
N. Engl. J. Med. 329, 1169-1173
 |  Full Text »

Somatic Gene Therapy: Methods for the Present and Future.

B. W. O'Malley Jr and F. D. Ledley (1993)
Arch Otolaryngol Head Neck Surg 119, 1100-1107
 |  Abstract »  |  PDF »

Pediatrics.

V. A. Fulginiti and J. E. Lewy (1993)
JAMA 270, 246-248
 |  Abstract »  |  PDF »

Molecular Targets of Gene Transfer Therapy for HIV Infection.

G. L. Buchschacher Jr (1993)
JAMA 269, 2880-2886
 |  Abstract »  |  PDF »

How Shall Research in the Treatment of Retinitis Pigmentosa Proceed?.

F. Wong (1993)
Arch Ophthalmol 111, 754-756
 |  Abstract »  |  PDF »

New startups move in as gene therapy goes commercial.

E Culotta (1993)
Science 260, 914-915
 |  PDF »

The basic science of gene therapy.

R. Mulligan (1993)
Science 260, 926-932
 |  Abstract »  |  PDF »

The American Medical Association Scientific Journals 1993 Theme Issues on Molecular Genetics and Medicine: Call for Papers.

C. T. Caskey, A. G. Motulsky, and W. W. McLendon (1993)
Arch Dermatol 129, 99-100
 |  Abstract »  |  PDF »

Molecular Genetics and Medicine: A Call for Papers.

C. T. Caskey, A. G. Motulsky, and W. W. McLendon (1992)
JAMA 268, 3241
 |  Abstract »  |  PDF »

Human Gene Therapy: A Role for the Primary Care Physician.

C. J. Schmeichel and J. M. Loeb (1992)
Arch Fam Med 1, 113-120
 |  Abstract »  |  PDF »

Structure-Based Strategies for Drug Design and Discovery.

I. D. Kuntz (1992)
Science 257, 1078-1082
 |  Abstract »  |  PDF »

Current Concepts in Embryonic Craniofacial Development.

G.H. Sperber (1992)
Critical Reviews in Oral Biology & Medicine 4, 67-72
 |  Full Text »  |  PDF »

Genetically engineered macrophages expressing IFN-gamma restore alveolar immune function in scid mice.

M. Wu, S. Hussain, Y.-H. He, R. Pasula, P. A. Smith, and W. J. Martin II (2001)
PNAS 98, 14589-14594
 |  Abstract »  |  Full Text »  |  PDF »

To Advertise   |   Find Products