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Science 1 May 1992:
Vol. 256. no. 5057, pp. 673 - 675
DOI: 10.1126/science.1585182
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Articles

Science, Vol 256, Issue 5057, 673-675
Copyright © 1992 by American Association for the Advancement of Science

articles

Occurrence of sialic acids in Drosophila melanogaster

J Roth, A Kempf, G Reuter, R Schauer, and WJ Gehring

Department of Cell Biology, University of Basel, Switzerland.

Sialylated oligosaccharides, which are cell type-specific and developmentally regulated, have been implicated in a variety of complex biological events. Their broad functional importance is reflected by their presence in a wide variety of phyla extending from Echinodermata through higher vertebrates. Here, sialic acids are detected throughout development in an insect, Drosophila. Homopolymers of alpha 2,8-linked sialic acid, polysialic acid, are developmentally regulated and only expressed during early Drosophila development.


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