Science 13 March 1992: Vol. 255. no. 5050, pp. 1434 - 1437 DOI: 10.1126/science.1542794

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Articles

Ciliary Neurotrophic Factor Stimulates Muscle Glucose Uptake by a PI3-Kinase-Dependent Pathway That Is Impaired With Obesity.

G. R. Steinberg, M. J. Watt, M. Ernst, M. J. Birnbaum, B. E. Kemp, and S. B. Jorgensen (2009)
Diabetes 58, 829-839
 |  Abstract »  |  Full Text »  |  PDF »

A Genetic Expression Profile Associated with Oral Cancer Identifies a Group of Patients at High Risk of Poor Survival.

E. Mendez, J. R. Houck, D. R. Doody, W. Fan, P. Lohavanichbutr, T. C. Rue, B. Yueh, N. D. Futran, M. P. Upton, D. G. Farwell, et al. (2009)
Clin. Cancer Res. 15, 1353-1361
 |  Abstract »  |  Full Text »  |  PDF »

Neurogenesis in the Dentate Gyrus Depends on Ciliary Neurotrophic Factor and Signal Transducer and Activator of Transcription 3 Signaling.

S. Muller, B. P.S. Chakrapani, H. Schwegler, H.-D. Hofmann, and M. Kirsch (2009)
Stem Cells 27, 431-441
 |  Abstract »  |  Full Text »  |  PDF »

Mice Overexpressing Murine Oncostatin M (OSM) Exhibit Changes in Hematopoietic and Other Organs that Are Distinct from Those of Mice Overexpressing Human OSM or Bovine OSM.

T.S.-C. Juan, B. Bolon, R. A. Lindberg, Y. Sun, G. Van, and F. A. Fletcher (2009)
Vet. Pathol. 46, 124-137
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of Oncostatin M-Induced Pulmonary Inflammation and Fibrosis.

A. Mozaffarian, A. W. Brewer, E. S. Trueblood, I. G. Luzina, N. W. Todd, S. P. Atamas, and H. A. Arnett (2008)
J. Immunol. 181, 7243-7253
 |  Abstract »  |  Full Text »  |  PDF »

The "Bubble Boy" Paradox: An Answer That Led to a Question.

L. J. Berg (2008)
J. Immunol. 181, 5815-5816
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Activation of Akt through gp130 Receptor Signaling Is Required for Kaposi's Sarcoma-Associated Herpesvirus-Induced Lymphatic Reprogramming of Endothelial Cells.

V. A. Morris, A. S. Punjabi, and M. Lagunoff (2008)
J. Virol. 82, 8771-8779
 |  Abstract »  |  Full Text »  |  PDF »

c-Cbl-Dependent Monoubiquitination and Lysosomal Degradation of gp130.

Y. Tanaka, N. Tanaka, Y. Saeki, K. Tanaka, M. Murakami, T. Hirano, N. Ishii, and K. Sugamura (2008)
Mol. Cell. Biol. 28, 4805-4818
 |  Abstract »  |  Full Text »  |  PDF »

Mutation of Prkar1a Causes Osteoblast Neoplasia Driven by Dysregulation of Protein Kinase A.

E. Pavel, K. Nadella, W. H. Towns II, and L. S. Kirschner (2008)
Mol. Endocrinol. 22, 430-440
 |  Abstract »  |  Full Text »  |  PDF »

Leukemia inhibitory factor ligand-receptor signaling is important for uterine receptivity and implantation in golden hamsters (Mesocricetus auratus).

T. Ding, H. Song, X. Wang, A. Khatua, and B. C Paria (2008)
Reproduction 135, 41-53
 |  Abstract »  |  Full Text »  |  PDF »

Oncostatin M Secreted by Skin Infiltrating T Lymphocytes Is a Potent Keratinocyte Activator Involved in Skin Inflammation.

K. Boniface, C. Diveu, F. Morel, N. Pedretti, J. Froger, E. Ravon, M. Garcia, E. Venereau, L. Preisser, E. Guignouard, et al. (2007)
J. Immunol. 178, 4615-4622
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of the Interleukin (IL)-6 Inhibitor IL-6-RFP: FUSED RECEPTOR DOMAINS ACT AS HIGH AFFINITY CYTOKINE-BINDING PROTEINS.

S. Metz, M. Wiesinger, M. Vogt, H. Lauks, G. Schmalzing, P. C. Heinrich, and G. Muller-Newen (2007)
J. Biol. Chem. 282, 1238-1248
 |  Abstract »  |  Full Text »  |  PDF »

Molecular and Functional Characterization of a Soluble Form of Oncostatin M/Interleukin-31 Shared Receptor.

C. Diveu, E. Venereau, J. Froger, E. Ravon, L. Grimaud, F. Rousseau, S. Chevalier, and H. Gascan (2006)
J. Biol. Chem. 281, 36673-36682
 |  Abstract »  |  Full Text »  |  PDF »

Oncostatin M (OSM) Cytostasis of Breast Tumor Cells: Characterization of an OSM Receptor {beta}-Specific Kernel..

N. Underhill-Day and J. K. Heath (2006)
Cancer Res. 66, 10891-10901
 |  Abstract »  |  Full Text »  |  PDF »

Continued Administration of Ciliary Neurotrophic Factor Protects Mice from Inflammatory Pathology in Experimental Autoimmune Encephalomyelitis.

T. Kuhlmann, L. Remington, I. Cognet, L. Bourbonniere, S. Zehntner, F. Guilhot, A. Herman, A. Guay-Giroux, J. P. Antel, T. Owens, et al. (2006)
Am. J. Pathol. 169, 584-598
 |  Abstract »  |  Full Text »  |  PDF »

Loss of Leukemia Inhibitory Factor Receptor beta or Cardiotrophin-1 Causes Similar Deficits in Preganglionic Sympathetic Neurons and Adrenal Medulla.

S. Oberle, A. Schober, V. Meyer, B. Holtmann, C. Henderson, M. Sendtner, and K. Unsicker (2006)
J. Neurosci. 26, 1823-1832
 |  Abstract »  |  Full Text »  |  PDF »

Dimerization of the cytokine receptors gp130 and LIFR analysed in single cells.

B. Giese, C. Roderburg, M. Sommerauer, S. B. Wortmann, S. Metz, P. C. Heinrich, and G. Muller-Newen (2005)
J. Cell Sci. 118, 5129-5140
 |  Abstract »  |  Full Text »  |  PDF »

Cross-talk among gp130 Cytokines in Adipocytes.

S. Zvonic, J. E. Baugh Jr., P. Arbour-Reily, R. L. Mynatt, and J. M. Stephens (2005)
J. Biol. Chem. 280, 33856-33863
 |  Abstract »  |  Full Text »  |  PDF »

Evidence of a new leukemia inhibitory factor-associated genetic marker for litter size in a synthetic pig line.

A. Spotter, C. Drogemuller, H. Hamann, and O. Distl (2005)
J Anim Sci 83, 2264-2270
 |  Abstract »  |  Full Text »  |  PDF »

Mammary Gland Remodeling Depends on gp130 Signaling through Stat3 and MAPK.

L. Zhao, S. Hart, J. Cheng, J. J. Melenhorst, B. Bierie, M. Ernst, C. Stewart, F. Schaper, P. C. Heinrich, A. Ullrich, et al. (2004)
J. Biol. Chem. 279, 44093-44100
 |  Abstract »  |  Full Text »  |  PDF »

Signal transducer and activator of transcription 3 (Stat3) expression and activation in rat uterus during early pregnancy.

C.-B. Teng, H.-L. Diao, H. Ma, J. Cong, H. Yu, X.-H. Ma, L.-B. Xu, and Z.-M. Yang (2004)
Reproduction 128, 197-205
 |  Abstract »  |  Full Text »  |  PDF »

Chicken Leukemia Inhibitory Factor Maintains Chicken Embryonic Stem Cells in the Undifferentiated State.

H. Horiuchi, A. Tategaki, Y. Yamashita, H. Hisamatsu, M. Ogawa, T. Noguchi, M. Aosasa, T. Kawashima, S. Akita, N. Nishimichi, et al. (2004)
J. Biol. Chem. 279, 24514-24520
 |  Abstract »  |  Full Text »  |  PDF »

Pharmacokinetics of Recombinant Human Leukemia Inhibitory Factor in Sheep.

A. M. Segrave, D. E. Mager, S. A. Charman, G. A. Edwards, and C. J. H. Porter (2004)
J. Pharmacol. Exp. Ther. 309, 1085-1092
 |  Abstract »  |  Full Text »  |  PDF »

Polarity and lipid raft association of the components of the ciliary neurotrophic factor receptor complex in Madin-Darby canine kidney cells.

D. M. Buk, M. Waibel, C. Braig, A. S. Martens, P. C. Heinrich, and L. Graeve (2004)
J. Cell Sci. 117, 2063-2075
 |  Abstract »  |  Full Text »  |  PDF »

Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor.

D. Derouet, F. Rousseau, F. Alfonsi, J. Froger, J. Hermann, F. Barbier, D. Perret, C. Diveu, C. Guillet, L. Preisser, et al. (2004)
PNAS 101, 4827-4832
 |  Abstract »  |  Full Text »  |  PDF »

Affinity Maturation of Leukemia Inhibitory Factor and Conversion to Potent Antagonists of Signaling.

W. D. Fairlie, A. D. Uboldi, J. E. McCoubrie, C. C. Wang, E. F. Lee, S. Yao, D. P. De Souza, S. Mifsud, D. Metcalf, N. A. Nicola, et al. (2004)
J. Biol. Chem. 279, 2125-2134
 |  Abstract »  |  Full Text »  |  PDF »

GPL, a Novel Cytokine Receptor Related to GP130 and Leukemia Inhibitory Factor Receptor.

C. Diveu, E. Lelievre, D. Perret, A.-H. L. Lak-Hal, J. Froger, C. Guillet, S. Chevalier, F. Rousseau, A. Wesa, L. Preisser, et al. (2003)
J. Biol. Chem. 278, 49850-49859
 |  Abstract »  |  Full Text »  |  PDF »

Targeted disruption of oncostatin M receptor results in altered hematopoiesis.

M. Tanaka, Y. Hirabayashi, T. Sekiguchi, T. Inoue, M. Katsuki, and A. Miyajima (2003)
Blood 102, 3154-3162
 |  Abstract »  |  Full Text »  |  PDF »

Role of Monocytes in Atherogenesis.

B. OSTERUD and E. BJORKLID (2003)
Physiol Rev 83, 1069-1112
 |  Abstract »  |  Full Text »  |  PDF »

Leukemia Inhibitory Factor (LIF), Cardiotrophin-1, and Oncostatin M Share Structural Binding Determinants in the Immunoglobulin-like Domain of LIF Receptor.

H. Plun-Favreau, D. Perret, C. Diveu, J. Froger, S. Chevalier, E. Lelievre, H. Gascan, and M. Chabbert (2003)
J. Biol. Chem. 278, 27169-27179
 |  Abstract »  |  Full Text »  |  PDF »

A Phase I Study of Recombinant Human Leukemia Inhibitory Factor in Patients with Advanced Cancer.

D. H. Gunawardana, R. L. Basser, I. D. Davis, J. Cebon, P. Mitchell, C. Underhill, T. J. Kilpatrick, K. Reardon, M. D. Green, P. Bardy, et al. (2003)
Clin. Cancer Res. 9, 2056-2065
 |  Abstract »  |  Full Text »  |  PDF »

Cytokine Suppression of Dopamine-beta -hydroxylase by Extracellular Signal-regulated Kinase-dependent and -independent Pathways.

S. Dziennis and B. A. Habecker (2003)
J. Biol. Chem. 278, 15897-15904
 |  Abstract »  |  Full Text »  |  PDF »

Interleukins in Atherosclerosis: Molecular Pathways and Therapeutic Potential.

J. H. Von der Thusen, J. Kuiper, T. J. C. Van Berkel, and E. A. L. Biessen (2003)
Pharmacol. Rev. 55, 133-166
 |  Abstract »  |  Full Text »  |  PDF »

Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130.

M. Hayashi, M.-C. Rho, A. Enomoto, A. Fukami, Y.-P. Kim, Y. Kikuchi, T. Sunazuka, T. Hirose, K. Komiyama, and S. Omura (2002)
PNAS 99, 14728-14733
 |  Abstract »  |  Full Text »  |  PDF »

Biological Activity of a Novel Nonpeptide Antagonist to the Interleukin-6 Receptor 20S,21-Epoxy-resibufogenin-3-formate.

M. Hayashi, M.-C. Rho, A. Fukami, A. Enomoto, S. Nonaka, Y. Sekiguchi, T. Yanagisawa, A. Yamashita, T. Nogawa, Y. Kamano, et al. (2002)
J. Pharmacol. Exp. Ther. 303, 104-109
 |  Abstract »  |  Full Text »  |  PDF »

Differential Toxicogenomic Responses to 2,3,7,8-Tetrachlorodibenzo-p-dioxin in Malignant and Nonmalignant Human Airway Epithelial Cells.

J. M. Martinez, C. A. Afshari, P. R. Bushel, A. Masuda, T. Takahashi, and N. J. Walker (2002)
Toxicol. Sci. 69, 409-423
 |  Abstract »  |  Full Text »  |  PDF »

Ligand/Receptor Signaling Threshold (LIST) Model Accounts for gp130-Mediated Embryonic Stem Cell Self-Renewal Responses to LIF and HIL-6.

S. Viswanathan, T. Benatar, S. Rose-John, D. A. Lauffenburger, and P. W. Zandstra (2002)
Stem Cells 20, 119-138
 |  Abstract »  |  Full Text »  |  PDF »

Exclusive Neutrophil Recruitment with Oncostatin M in a Human System.

S. M. Kerfoot, E. Raharjo, M. Ho, J. Kaur, S. Serirom, D.-M. McCafferty, A. R. Burns, K. D. Patel, and P. Kubes (2001)
Am. J. Pathol. 159, 1531-1539
 |  Abstract »  |  Full Text »

Menstrual cycle-specific inhibition of endometrial stromal cell proliferation by oncostatin M.

Y. Ohata, T. Harada, A. Fujii, S. Yoshida, T. Iwabe, and N. Terakawa (2001)
Mol. Hum. Reprod. 7, 665-670
 |  Abstract »  |  Full Text »  |  PDF »

Expression of interleukin-11 during the human menstrual cycle: coincidence with stromal cell decidualization and relationship to leukaemia inhibitory factor and prolactin.

E. Dimitriadis, L.A. Salamonsen, and L. Robb (2000)
Mol. Hum. Reprod. 6, 907-914
 |  Abstract »  |  Full Text »  |  PDF »

Signal Transduction of IL-6, Leukemia-Inhibitory Factor, and Oncostatin M: Structural Receptor Requirements for Signal Attenuation.

D. Anhuf, M. Weissenbach, J. Schmitz, R. Sobota, H. M. Hermanns, S. Radtke, S. Linnemann, I. Behrmann, P. C. Heinrich, and F. Schaper (2000)
J. Immunol. 165, 2535-2543
 |  Abstract »  |  Full Text »  |  PDF »

Leukemia Inhibitory Factor, Leukemia Inhibitory Factor Receptor, and Glycoprotein 130 in Rhesus Monkey Uterus During Menstrual Cycle and Early Pregnancy.

Z.-P. Yue, Z.-M. Yang, P. Wei, S.-J. Li, H.-B. Wang, J.-H. Tan, and M. J.K. Harper (2000)
Biol Reprod 63, 508-512
 |  Abstract »  |  Full Text »

Constitutive Stat3, Tyr705, and Ser727 phosphorylation in acute myeloid leukemia cells caused by the autocrine secretion of interleukin-6.

J.-J. Schuringa, A. T. J. Wierenga, W. Kruijer, and E. Vellenga (2000)
Blood 95, 3765-3770
 |  Abstract »  |  Full Text »  |  PDF »

Leukemia-Inhibitory Factor--Neuroimmune Modulator of Endocrine Function.

C. J. Auernhammer and S. Melmed (2000)
Endocr. Rev. 21, 313-345
 |  Abstract »  |  Full Text »

Leukemia Inhibitory Factor Modulates Cardiogenesis in Embryoid Bodies in Opposite Fashions.

A. Bader, H. Al-Dubai, and G. Weitzer (2000)
Circ. Res. 86, 787-794
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a gp130 Cytokine Receptor Critical Site Involved in Oncostatin M Response.

C. Olivier, P. Auguste, M. Chabbert, E. Lelievre, S. Chevalier, and H. Gascan (2000)
J. Biol. Chem. 275, 5648-5656
 |  Abstract »  |  Full Text »  |  PDF »

Potential role of LIF as a modifier gene in the pathogenesis of amyotrophic lateral sclerosis.

R. Giess, M. Beck, R. Goetz, R. M. Nitsch, K. V. Toyka, and M. Sendtner (2000)
Neurology 54, 1003-1005
 |  Abstract »  |  Full Text »  |  PDF »

Studies on the Interleukin-6-type Cytokine Signal Transducer gp130 Reveal a Novel Mechanism of Receptor Activation by Monoclonal Antibodies.

G. Muller-Newen, A. Kuster, J. Wijdenes, F. Schaper, and P. C. Heinrich (2000)
J. Biol. Chem. 275, 4579-4586
 |  Abstract »  |  Full Text »  |  PDF »

Importance of the Membrane-Proximal Extracellular Domains for Activation of the Signal Transducer Glycoprotein 130.

I. Kurth, U. Horsten, S. Pflanz, A. Timmermann, A. Kuster, H. Dahmen, I. Tacken, P. C. Heinrich, and G. Muller-Newen (2000)
J. Immunol. 164, 273-282
 |  Abstract »  |  Full Text »  |  PDF »

Novel neurotrophin-1/B cell-stimulating factor-3: A cytokine of the IL-6 family.

G. Senaldi, B. C. Varnum, U. Sarmiento, C. Starnes, J. Lile, S. Scully, J. Guo, G. Elliott, J. McNinch, C. L. Shaklee, et al. (1999)
PNAS 96, 11458-11463
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Oncostatin M-inducible Gene OIG37 Forms a Gene Family with MyD118 and GADD45 and Negatively Regulates Cell Growth.

K. Nakayama, T. Hara, M. Hibi, T. Hirano, and A. Miyajima (1999)
J. Biol. Chem. 274, 24766-24772
 |  Abstract »  |  Full Text »  |  PDF »

Oncostatin M Induces Angiogenesis In Vitro and In Vivo.

M. Vasse, J. Pourtau, V. Trochon, M. Muraine, J.-P. Vannier, H. Lu, J. Soria, and C. Soria (1999)
Arterioscler. Thromb. Vasc. Biol. 19, 1835-1842
 |  Abstract »  |  Full Text »  |  PDF »

Recruitment of a Heparan Sulfate Subunit to the Interleukin-1 Receptor Complex. REGULATION BY FIBRONECTIN ATTACHMENT.

S. Valles, C. Tsoi, W.-Y. Huang, D. Wyllie, F. Carlotti, J. A. Askari, M. J. Humphries, S. K. Dower, and E. E. Qwarnstrom (1999)
J. Biol. Chem. 274, 20103-20109
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-6 (IL-6) Production by Astrocytes: Autocrine Regulation by IL-6 and the Soluble IL-6 Receptor.

N. J. Van Wagoner, J.-W. Oh, P. Repovic, and E. N. Benveniste (1999)
J. Neurosci. 19, 5236-5244
 |  Abstract »  |  Full Text »  |  PDF »

Leukaemia inhibitory factor gene mutations in infertile women.

R. Giess, I. Tanasescu, T. Steck, and M. Sendtner (1999)
Mol. Hum. Reprod. 5, 581-586
 |  Abstract »  |  Full Text »  |  PDF »

Evaluation of the effect of interleukin-6 and human extracellullar matrix on embryonic development.

N. Desai, M. Scarrow, J. Lawson, D. Kinzer, and J. Goldfarb (1999)
Hum. Reprod. 14, 1588-1592
 |  Abstract »  |  Full Text »  |  PDF »

Binding of Leukemia Inhibitory Factor (LIF) to Mutants of Its Low Affinity Receptor, gp190, Reveals a LIF Binding Site Outside and Interactions between the Two Cytokine Binding Domains.

J.-L. Taupin, V. Miossec, V. Pitard, F. Blanchard, S. Daburon, S. Raher, Y. Jacques, A. Godard, and J.-F. Moreau (1999)
J. Biol. Chem. 274, 14482-14489
 |  Abstract »  |  Full Text »  |  PDF »

Critical Role for STAT3 in Murine Pituitary Adrenocorticotropin Hormone Leukemia Inhibitory Factor Signaling.

C. Bousquet and S. Melmed (1999)
J. Biol. Chem. 274, 10723-10730
 |  Abstract »  |  Full Text »  |  PDF »

Ciliary Neurotrophic Factor is a Regulator of Muscular Strength in Aging.

C. Guillet, P. Auguste, W. Mayo, P. Kreher, and H. Gascan (1999)
J. Neurosci. 19, 1257-1262
 |  Abstract »  |  Full Text »  |  PDF »

Localization of Leukemia Inhibitory Factor and Its Receptor in Human Placenta Throughout Pregnancy.

A.M. Sharkey, A. King, D.E. Clark, T.D. Burrows, P.P. Jokhi, D.S. Charnock-Jones, Y.W. Loke, and S.K. Smith (1999)
Biol Reprod 60, 355-364
 |  Abstract »  |  Full Text »  |  PDF »

Activation of the Signal Transducer Glycoprotein 130 by Both IL-6 and IL-11 Requires Two Distinct Binding Epitopes.

I. Kurth, U. Horsten, S. Pflanz, H. Dahmen, A. Kuster, J. Grotzinger, P. C. Heinrich, and G. Muller-Newen (1999)
J. Immunol. 162, 1480-1487
 |  Abstract »  |  Full Text »  |  PDF »

Reconstitution of the Functional Mouse Oncostatin M (OSM) Receptor: Molecular Cloning of the Mouse OSM Receptor beta  Subunit.

M. Tanaka, T. Hara, N. G. Copeland, D. J. Gilbert, N. A. Jenkins, and A. Miyajima (1999)
Blood 93, 804-815
 |  Abstract »  |  Full Text »  |  PDF »

The Box-1 Region of the Leukemia Inhibitory Factor Receptor alpha -Chain Cytoplasmic Domain Is Sufficient for Hemopoietic Cell Proliferation and Differentiation.

Y. Zhang, T. Willson, D. Metcalf, D. Cary, D. J. Hilton, R. Clark, and N. A. Nicola (1998)
J. Biol. Chem. 273, 34370-34383
 |  Abstract »  |  Full Text »  |  PDF »

Functional Map of a Placenta-specific Enhancer of the Human Leukemia Inhibitory Factor Receptor Gene.

Z. Wang and S. Melmed (1998)
J. Biol. Chem. 273, 26069-26077
 |  Abstract »  |  Full Text »  |  PDF »

Reciprocal Regulation of Ciliary Neurotrophic Factor Receptors and Acetylcholine Receptors during Synaptogenesis in Embryonic Chick Atria.

X. Wang and S. W. Halvorsen (1998)
J. Neurosci. 18, 7372-7380
 |  Abstract »  |  Full Text »  |  PDF »

Leptin causes body weight loss in the absence of in vivo activities typical of cytokines of the IL-6 family.

D. Agnello, C. Meazza, C. G. Rowan, P. Villa, P. Ghezzi, and G. Senaldi (1998)
Am J Physiol Regulatory Integrative Comp Physiol 275, R913-R919
 |  Abstract »  |  Full Text »  |  PDF »

The Immunoglobulin-like Module of gp130 Is Required for Signaling by Interleukin-6, but Not by Leukemia Inhibitory Factor.

A. Hammacher, R. T. Richardson, J. E. Layton, D. K. Smith, L. J. L. Angus, D. J. Hilton, N. A. Nicola, J. Wijdenes, and R. J. Simpson (1998)
J. Biol. Chem. 273, 22701-22707
 |  Abstract »  |  Full Text »  |  PDF »

The Mannose 6-Phosphate/Insulin-like Growth Factor II Receptor Is a Nanomolar Affinity Receptor for Glycosylated Human Leukemia Inhibitory Factor.

F. Blanchard, S. Raher, L. Duplomb, P. Vusio, V. Pitard, J.-L. Taupin, J.-F. Moreau, B. Hoflack, S. Minvielle, Y. Jacques, et al. (1998)
J. Biol. Chem. 273, 20886-20893
 |  Abstract »  |  Full Text »  |  PDF »

Cytokine-Like Factor-1, a Novel Soluble Protein, Shares Homology with Members of the Cytokine Type I Receptor Family.

G. C. A. Elson, P. Graber, C. Losberger, S. Herren, D. Gretener, L. N. Menoud, T. N. C. Wells, M. H. Kosco-Vilbois, and J.-F. Gauchat (1998)
J. Immunol. 161, 1371-1379
 |  Abstract »  |  Full Text »  |  PDF »

Pituitary Corticotroph SOCS-3: Novel Intracellular Regulation of Leukemia-Inhibitory Factor-Mediated Proopiomelanocortin Gene Expression and Adrenocorticotropin Secretion.

C. J. Auernhammer, V. Chesnokova, C. Bousquet, and S. Melmed (1998)
Mol. Endocrinol. 12, 954-961
 |  Abstract »  |  Full Text »

Cloning and Characterization of a Specific Receptor for Mouse Oncostatin M.

R. A. Lindberg, T. S.-C. Juan, A. A. Welcher, Y. Sun, R. Cupples, B. Guthrie, and F. A. Fletcher (1998)
Mol. Cell. Biol. 18, 3357-3367
 |  Abstract »  |  Full Text »

Identification and Characterization of Two Distinct Truncated Forms of gp130 and a Soluble Form of Leukemia Inhibitory Factor Receptor alpha -Chain in Normal Human Urine and Plasma.

J.-G. Zhang, Y. Zhang, C. M. Owczarek, L. D. Ward, R. L. Moritz, R. J. Simpson, K. Yasukawa, and N. A. Nicola (1998)
J. Biol. Chem. 273, 10798-10805
 |  Abstract »  |  Full Text »  |  PDF »

Oncostatin M Down-regulates Basal and Induced Cytochromes P450 in Human Hepatocytes.

M. I. Guillén, M. T. Donato, R. Jover, J. V. Castell, R. Fabra, R. Trullenque, and M. J. Gómez-Lechón (1998)
J. Pharmacol. Exp. Ther. 285, 127-134
 |  Abstract »  |  Full Text »

Oncostatin M Is a Potent Stimulator of alpha 1-Antitrypsin Secretion in Lung Epithelial Cells: Modulation by Transforming Growth Factor-beta and Interferon-gamma.

A. Boutten, P. Venembre, N. Seta, J. Hamelin, M. Aubier, G. Durand, and M. S. Dehoux (1998)
Am. J. Respir. Cell Mol. Biol. 18, 511-520
 |  Abstract »  |  Full Text »

Sympathetic neurons can produce and respond to interleukin 6.

P. Marz, J.-G. Cheng, R. A. Gadient, P. H. Patterson, T. Stoyan, U. Otten, and S. Rose-John (1998)
PNAS 95, 3251-3256
 |  Abstract »  |  Full Text »  |  PDF »

STAT3 Acts as a Co-activator of Glucocorticoid Receptor Signaling.

Z. Zhang, S. Jones, J. S. Hagood, N. L. Fuentes, and G. M. Fuller (1997)
J. Biol. Chem. 272, 30607-30610
 |  Abstract »  |  Full Text »  |  PDF »

Transmembrane Domain of gp130 Contributes to Intracellular Signal Transduction in Hepatic Cells.

H. Kim and H. Baumann (1997)
J. Biol. Chem. 272, 30741-30747
 |  Abstract »  |  Full Text »  |  PDF »

Synergistic Action of Flt3 and gp130 Signalings in Human Hematopoiesis.

Y. Ebihara, K. Tsuji, S. D. Lyman, X. Sui, M. Yoshida, K. Muraoka, K. Yamada, R. Tanaka, and T. Nakahata (1997)
Blood 90, 4363-4368
 |  Abstract »  |  Full Text »  |  PDF »

Recombinant Soluble Interleukin-11 (IL-11) Receptor alpha -Chain Can Act as an IL-11 Antagonist.

D. J. Curtis, D. J. Hilton, B. Roberts, L. Murray, N. Nicola, and C. G. Begley (1997)
Blood 90, 4403-4412
 |  Abstract »  |  Full Text »  |  PDF »

A Sweat Gland-derived Differentiation Activity Acts through Known Cytokine Signaling Pathways.

B. A. Habecker, A. J. Symes, N. Stahl, N. J. Francis, A. Economides, J. S. Fink, G. D. Yancopoulos, and S. C. Landis (1997)
J. Biol. Chem. 272, 30421-30428
 |  Abstract »  |  Full Text »  |  PDF »

Leukemia Inhibitory Factor, a Potent Cardiac Hypertrophic Cytokine, Activates the JAK/STAT Pathway in Rat Cardiomyocytes.

H. Kodama, K. Fukuda, J. Pan, S. Makino, A. Baba, S. Hori, and S. Ogawa (1997)
Circ. Res. 81, 656-663
 |  Abstract »  |  Full Text »

Identification of an Upstream Enhancer within a Functional Promoter of the Human Leukemia Inhibitory Factor Receptor Gene and Its Alternative Promoter Usage.

Z. Wang and S. Melmed (1997)
J. Biol. Chem. 272, 27957-27965
 |  Abstract »  |  Full Text »  |  PDF »

An Antagonist for the Leukemia Inhibitory Factor Receptor Inhibits Leukemia Inhibitory Factor, Cardiotrophin-1, Ciliary Neurotrophic Factor, and Oncostatin M.

A. B. Vernallis, K. R. Hudson, and J. K. Heath (1997)
J. Biol. Chem. 272, 26947-26952
 |  Abstract »  |  Full Text »  |  PDF »

The Unusual Species Cross-reactivity of the Leukemia Inhibitory Factor Receptor alpha -Chain Is Determined Primarily by the Immunoglobulin-like Domain.

C. M. Owczarek, Y. Zhang, M. J. Layton, D. Metcalf, B. Roberts, and N. A. Nicola (1997)
J. Biol. Chem. 272, 23976-23985
 |  Abstract »  |  Full Text »  |  PDF »

Ciliary Neurotrophic Factor Stimulates the Phosphorylation of Two Forms of STAT3 in Chick Ciliary Ganglion Neurons.

M. A. Wishingrad, S. Koshlukova, and S. W. Halvorsen (1997)
J. Biol. Chem. 272, 19752-19757
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Roles for Leukemia Inhibitory Factor Receptor alpha -Chain and gp130 in Cell Type-specific Signal Transduction.

R. Starr, U. Novak, T. A. Willson, M. Inglese, V. Murphy, W. S. Alexander, D. Metcalf, N. A. Nicola, D. J. Hilton, and M. Ernst (1997)
J. Biol. Chem. 272, 19982-19986
 |  Abstract »  |  Full Text »  |  PDF »

HNMP-1: A Novel Hematopoietic and Neural Membrane Protein Differentially Regulated in Neural Development and Injury.

L. M. Bolin, T. McNeil, L. A. Lucian, B. DeVaux, K. Franz-Bacon, D. M. Gorman, S. Zurawski, R. Murray, and T. K. McClanahan (1997)
J. Neurosci. 17, 5493-5502
 |  Abstract »  |  Full Text »  |  PDF »

Oncostatin M and Leukemia Inhibitory Factor Do Not Use the Same Functional Receptor in Mice.

M. Ichihara, T. Hara, H. Kim, T. Murate, and A. Miyajima (1997)
Blood 90, 165-173
 |  Abstract »  |  Full Text »  |  PDF »

Box 3-independent Signaling Mechanisms Are Involved in Leukemia Inhibitory Factor Receptor alpha - and gp130-mediated Stimulation of Mitogen-activated Protein Kinase. EVIDENCE FOR PARTICIPATION OF MULTIPLE SIGNALING PATHWAYS WHICH CONVERGE AT Ras.

W. P. Schiemann, J. L. Bartoe, and N. M. Nathanson (1997)
J. Biol. Chem. 272, 16631-16636
 |  Abstract »  |  Full Text »  |  PDF »

Signaling of Type II Oncostatin M Receptor.

P. Auguste, C. Guillet, M. Fourcin, C. Olivier, J. Veziers, A. Pouplard-Barthelaix, and H. Gascan (1997)
J. Biol. Chem. 272, 15760-15764
 |  Abstract »  |  Full Text »  |  PDF »

Influence of Subunit Combinations on Signaling by Receptors for Oncostatin M, Leukemia Inhibitory Factor, and Interleukin-6.

K. K. Kuropatwinski, C. De Imus, D. Gearing, H. Baumann, and B. Mosley (1997)
J. Biol. Chem. 272, 15135-15144
 |  Abstract »  |  Full Text »  |  PDF »

Integration of Jak-Stat and AP-1 Signaling Pathways at the Vasoactive Intestinal Peptide Cytokine Response Element Regulates Ciliary Neurotrophic Factor-dependent Transcription.

A. Symes, T. Gearan, J. Eby, and J. S. Fink (1997)
J. Biol. Chem. 272, 9648-9654
 |  Abstract »  |  Full Text »  |  PDF »

Biosynthesis of alpha 1-Proteinase Inhibitor by Human Lung-derived Epithelial Cells.

J. Cichy, J. Potempa, and J. Travis (1997)
J. Biol. Chem. 272, 8250-8255
 |  Abstract »  |  Full Text »  |  PDF »

Impairment of antigen-specific antibody production in transgenic mice expressing a dominant-negative form of gp130.

A. Kumanogoh, S. Marukawa, T. Kumanogoh, H. Hirota, K. Yoshida, I.-S. Lee, T. Yasui, K. Yoshida, T. Taga, and T. Kishimoto (1997)
PNAS 94, 2478-2482
 |  Abstract »  |  Full Text »  |  PDF »

Signaling of the Cardiotrophin-1 Receptor. EVIDENCE FOR A THIRD RECEPTOR COMPONENT.

O. Robledo, M. Fourcin, S. Chevalier, C. Guillet, P. Auguste, A. Pouplard-Barthelaix, D. Pennica, and H. Gascan (1997)
J. Biol. Chem. 272, 4855-4863
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin (IL)-6 Directs the Differentiation of IL-4-producing CD4+ T Cells.

M. Rincon, J. Anguita, T. Nakamura, E. Fikrig, and R. A. Flavell (1997)
J. Exp. Med. 185, 461-470
 |  Abstract »  |  Full Text »  |  PDF »

Activating Mutations in Cytokine Receptors: Implications for Receptor Function and Role in Disease.

T. J. Gonda and R. J. D'Andrea (1997)
Blood 89, 355-369
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Oncostatin M induces basic fibroblast growth factor expression in endothelial cells and promotes endothelial cell proliferation, migration and spindle morphology.

E. Wijelath, B Carlsen, T Cole, J Chen, S Kothari, and W. Hammond (1997)
J. Cell Sci. 110, 871-879
 |  Abstract »  |  PDF »

Dual Oncostatin M (OSM) Receptors. CLONING AND CHARACTERIZATION OF AN ALTERNATIVE SIGNALING SUBUNIT CONFERRING OSM-SPECIFIC RECEPTOR ACTIVATION.

B. Mosley, C. De Imus, D. Friend, N. Boiani, B. Thoma, L. S. Park, and D. Cosman (1996)
J. Biol. Chem. 271, 32635-32643
 |  Abstract »  |  Full Text »  |  PDF »

Functional Expression of Soluble Human Interleukin-11 (IL-11) Receptor alpha and Stoichiometry of in Vitro IL-11 Receptor Complexes with gp130.

P. Neddermann, R. Graziani, G. Ciliberto, and G. Paonessa (1996)
J. Biol. Chem. 271, 30986-30991
 |  Abstract »  |  Full Text »  |  PDF »

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