Science 13 March 1992: Vol. 255. no. 5050, pp. 1432 - 1434 DOI: 10.1126/science.1542793

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Mice Overexpressing Murine Oncostatin M (OSM) Exhibit Changes in Hematopoietic and Other Organs that Are Distinct from Those of Mice Overexpressing Human OSM or Bovine OSM.

T.S.-C. Juan, B. Bolon, R. A. Lindberg, Y. Sun, G. Van, and F. A. Fletcher (2009)
Vet. Pathol. 46, 124-137
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A Dual Role for Oncostatin M Signaling in the Differentiation and Death of Mammary Epithelial Cells in Vivo.

P. G. Tiffen, N. Omidvar, N. Marquez-Almuina, D. Croston, C. J. Watson, and R. W. E. Clarkson (2008)
Mol. Endocrinol. 22, 2677-2688
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Box 2 Region of the Oncostatin M Receptor Determines Specificity for Recruitment of Janus Kinases and STAT5 Activation.

C. Hintzen, C. Evers, B. E. Lippok, R. Volkmer, P. C. Heinrich, S. Radtke, and H. M. Hermanns (2008)
J. Biol. Chem. 283, 19465-19477
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Molecular and Functional Characterization of a Soluble Form of Oncostatin M/Interleukin-31 Shared Receptor.

C. Diveu, E. Venereau, J. Froger, E. Ravon, L. Grimaud, F. Rousseau, S. Chevalier, and H. Gascan (2006)
J. Biol. Chem. 281, 36673-36682
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Oncostatin M Enhances CCL21 Expression by Microvascular Endothelial Cells and Increases the Efficiency of Dendritic Cell Trafficking to Lymph Nodes.

M. Sugaya, L. Fang, A. R. Cardones, T. Kakinuma, S. H. Jaber, A. Blauvelt, and S. T. Hwang (2006)
J. Immunol. 177, 7665-7672
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Overview of the Immune System and Use of Immunologic Biomarkers to Interrogate Cancer Etiology.

O. Martinez-Maza (2006)
Am. Assoc. Cancer Res. Educ. Book 2006, 31-34
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Comparative Study of Regulation of RTA-Responsive Genes in Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8.

M. J. Song, H. Deng, and R. Sun (2003)
J. Virol. 77, 9451-9462
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Molecular Genetics of Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Epidemiology and Pathogenesis.

L. A. Dourmishev, A. L. Dourmishev, D. Palmeri, R. A. Schwartz, and D. M. Lukac (2003)
Microbiol. Mol. Biol. Rev. 67, 175-212
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Oncostatin M Induces Growth Arrest of Mammary Epithelium via a CCAAT/enhancer-binding Protein {delta}-dependent Pathway.

J. A. Hutt and J. W. DeWille (2002)
Mol. Cancer Ther. 1, 601-610
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Characterization of Interactions between RTA and the Promoter of Polyadenylated Nuclear RNA in Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8.

M. J. Song, X. Li, H. J. Brown, and R. Sun (2002)
J. Virol. 76, 5000-5013
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Novel Role of Janus Kinase 1 in the Regulation of Oncostatin M Receptor Surface Expression.

S. Radtke, H. M. Hermanns, C. Haan, H. Schmitz-Van de Leur, H. Gascan, P. C. Heinrich, and I. Behrmann (2002)
J. Biol. Chem. 277, 11297-11305
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Menstrual cycle-specific inhibition of endometrial stromal cell proliferation by oncostatin M.

Y. Ohata, T. Harada, A. Fujii, S. Yoshida, T. Iwabe, and N. Terakawa (2001)
Mol. Hum. Reprod. 7, 665-670
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Transcription Activation of Polyadenylated Nuclear RNA by Rta in Human Herpesvirus 8/Kaposi's Sarcoma-Associated Herpesvirus.

M. J. Song, H. J. Brown, T.-T. Wu, and R. Sun (2001)
J. Virol. 75, 3129-3140
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Oncostatin M promotes biphasic tissue factor expression in smooth muscle cells: evidence for Erk-1/2 activation.

T. Nishibe, G. Parry, A. Ishida, S. Aziz, J. Murray, Y. Patel, S. Rahman, K. Strand, K. Saito, Y. Saito, et al. (2001)
Blood 97, 692-699
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Murine Oncostatin M Stimulates Mouse Synovial Fibroblasts in Vitro and Induces Inflammation and Destruction in Mouse Joints in Vivo.

C. Langdon, C. Kerr, M. Hassen, T. Hara, A. L. Arsenault, and C. D. Richards (2000)
Am. J. Pathol. 157, 1187-1196
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Sustained angiogenesis enables in vivo transplantation of mucocutaneous derived AIDS-related Kaposi's sarcoma cells in murine hosts.

S. R. Mallery, P. Pei, J. Kang, G. Zhu, G. M. Ness, and S. P. Schwendeman (2000)
Carcinogenesis 21, 1647-1653
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Oncostatin M Stimulates the Growth of Dermal Fibroblasts Via a Mitogen-Activated Protein Kinase-Dependent Pathway.

H. Ihn and K. Tamaki (2000)
J. Immunol. 165, 2149-2155
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Induction of HHV-8 Lytic Cycle Replication by Inflammatory Cytokines Produced by HIV-1-Infected T Cells.

M. Mercader, B. Taddeo, J. R. Panella, B. Chandran, B. J. Nickoloff, and K. E. Foreman (2000)
Am. J. Pathol. 156, 1961-1971
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Variant genotypes of Fcgamma RIIIA influence the development of Kaposi's sarcoma in HIV-infected men.

T. L. nbecher, C. B. Foster, S. Zhu, D. Venzon, S. M. Steinberg, K. Wyvill, J. A. Metcalf, S. S. Cohen, J. Kovacs, R. Yarchoan, et al. (2000)
Blood 95, 2386-2390
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Contributions of Leukemia Inhibitory Factor Receptor and Oncostatin M Receptor to Signal Transduction in Heterodimeric Complexes with Glycoprotein 130.

H. M. Hermanns, S. Radtke, C. Haan, H. Schmitz-Van de Leur, J. Tavernier, P. C. Heinrich, and I. Behrmann (1999)
J. Immunol. 163, 6651-6658
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Oncostatin M Induces Interleukin-6 and Cyclooxygenase-2 Expression in Human Vascular Smooth Muscle Cells : Synergy With Interleukin-1{beta}.

C. Bernard, R. Merval, M. Lebret, P. Delerive, I. Dusanter-Fourt, S. Lehoux, C. Creminon, B. Staels, J. Maclouf, and A. Tedgui (1999)
Circ. Res. 85, 1124-1131
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Perspective on Kaposi's Sarcoma: Facts, Concepts, and Conjectures.

M. S. Reitz Jr., L. S. Nerurkar, and R. C. Gallo (1999)
J Natl Cancer Inst 91, 1453-1458
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A Novel Oncostatin M-inducible Gene OIG37 Forms a Gene Family with MyD118 and GADD45 and Negatively Regulates Cell Growth.

K. Nakayama, T. Hara, M. Hibi, T. Hirano, and A. Miyajima (1999)
J. Biol. Chem. 274, 24766-24772
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Oncostatin M Induces Angiogenesis In Vitro and In Vivo.

M. Vasse, J. Pourtau, V. Trochon, M. Muraine, J.-P. Vannier, H. Lu, J. Soria, and C. Soria (1999)
Arterioscler. Thromb. Vasc. Biol. 19, 1835-1842
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Sensitization of AIDS-Kaposi's Sarcoma Cells to Apo-2 Ligand-Induced Apoptosis by Actinomycin D.

S. Mori, K. Murakami-Mori, S. Nakamura, A. Ashkenazi, and B. Bonavida (1999)
J. Immunol. 162, 5616-5623
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Implication of TNF Receptor-I-Mediated Extracellular Signal-Regulated Kinases 1 and 2 (ERK1/2) Activation in Growth of AIDS-Associated Kaposi's Sarcoma Cells: A Possible Role of a Novel Death Domain Protein MADD in TNF-{alpha}-Induced ERK1/2 Activation in Kaposi's Sarcoma Cells.

K. Murakami-Mori, S. Mori, B. Bonavida, and S. Nakamura (1999)
J. Immunol. 162, 3672-3679
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Kinetics of Kaposi's Sarcoma-Associated Herpesvirus Gene Expression.

R. Sun, S.-F. Lin, K. Staskus, L. Gradoville, E. Grogan, A. Haase, and G. Miller (1999)
J. Virol. 73, 2232-2242
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Reconstitution of the Functional Mouse Oncostatin M (OSM) Receptor: Molecular Cloning of the Mouse OSM Receptor beta  Subunit.

M. Tanaka, T. Hara, N. G. Copeland, D. J. Gilbert, N. A. Jenkins, and A. Miyajima (1999)
Blood 93, 804-815
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Cytokines, Plasma Immune Activation Markers, and Clinically Relevant Surrogate Markers in Human Immunodeficiency Virus Infection.

J. L. Fahey (1998)
Clin. Vaccine Immunol. 5, 597-603
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Endogenous Basic Fibroblast Growth Factor Is Essential for Cyclin E-CDK2 Activity in Multiple External Cytokine-Induced Proliferation of AIDS-Associated Kaposi's Sarcoma Cells: Dual Control of AIDS-Associated Kaposi's Sarcoma Cell Growth and Cyclin E-CDK2 Activity by Endogenous and External Signals.

K. Murakami-Mori, S. Mori, and S. Nakamura (1998)
J. Immunol. 161, 1694-1704
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Identification of Kaposin (Open Reading Frame K12) as a Human Herpesvirus 8 (Kaposi's Sarcoma-Associated Herpesvirus) Transforming Gene.

S. Muralidhar, A. M. Pumfery, M. Hassani, M. R. Sadaie, N. Azumi, M. Kishishita, J. N. Brady, J. Doniger, P. Medveczky, and L. J. Rosenthal (1998)
J. Virol. 72, 4980-4988
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Mechanisms of Growth Control of Kaposi's Sarcoma-Associated Herpes Virus-Associated Primary Effusion Lymphoma Cells.

H. Asou, J. W. Said, R. Yang, R. Munker, D. J. Park, N. Kamada, and H. P. Koeffler (1998)
Blood 91, 2475-2481
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gamma -Interferon Production in Peripheral Blood Mononuclear Cells and Tumor Infiltrating Lymphocytes From Kaposi's Sarcoma Patients: Correlation With the Presence of Human Herpesvirus-8 in Peripheral Blood Mononuclear Cells and Lesional Macrophages.

M. C. Sirianni, L. Vincenzi, V. Fiorelli, S. Topino, E. Scala, S. Uccini, A. Angeloni, A. Faggioni, D. Cerimele, F. Cottoni, et al. (1998)
Blood 91, 968-976
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Oncostatin M and Leukemia Inhibitory Factor Do Not Use the Same Functional Receptor in Mice.

M. Ichihara, T. Hara, H. Kim, T. Murate, and A. Miyajima (1997)
Blood 90, 165-173
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Signaling of Type II Oncostatin M Receptor.

P. Auguste, C. Guillet, M. Fourcin, C. Olivier, J. Veziers, A. Pouplard-Barthelaix, and H. Gascan (1997)
J. Biol. Chem. 272, 15760-15764
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Biosynthesis of alpha 1-Proteinase Inhibitor by Human Lung-derived Epithelial Cells.

J. Cichy, J. Potempa, and J. Travis (1997)
J. Biol. Chem. 272, 8250-8255
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The Mitogen-activated Protein Kinase and JAK-STAT Signaling Pathways Are Required for an Oncostatin M-responsive Element-mediated Activation of Matrix Metalloproteinase 1Gene Expression.

E. Korzus, H. Nagase, R. Rydell, and J. Travis (1997)
J. Biol. Chem. 272, 1188-1196
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Oncostatin M induces basic fibroblast growth factor expression in endothelial cells and promotes endothelial cell proliferation, migration and spindle morphology.

E. Wijelath, B Carlsen, T Cole, J Chen, S Kothari, and W. Hammond (1997)
J. Cell Sci. 110, 871-879
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Dual Oncostatin M (OSM) Receptors. CLONING AND CHARACTERIZATION OF AN ALTERNATIVE SIGNALING SUBUNIT CONFERRING OSM-SPECIFIC RECEPTOR ACTIVATION.

B. Mosley, C. De Imus, D. Friend, N. Boiani, B. Thoma, L. S. Park, and D. Cosman (1996)
J. Biol. Chem. 271, 32635-32643
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The Effects of Preparations of Human Chorionic Gonadotropin on AIDS-Related Kaposi's Sarcoma.

P. S. Gill, Y. Lunardi-Iskandar, S. Louie, A. Tulpule, T. Zheng, B. M. Espina, J. M. Besnier, P. Hermans, A. M. Levine, J. L. Bryant, et al. (1996)
N. Engl. J. Med. 335, 1261-1267
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Inhibition of Endothelial Cell Growth by Macrophage-like U-937 Cell-derived Oncostatin M, Leukemia Inhibitory Factor, and Transforming Growth Factor beta 1.

S. Takashima and M. Klagsbrun (1996)
J. Biol. Chem. 271, 24901-24906
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Kaposi's Sarcoma: Where Do We Go From Here?.

P. L. Myskowski (1993)
Arch Dermatol 129, 1320-1323
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Interleukin-6 and its receptor: a paradigm for cytokines.

T Kishimoto, S Akira, and T Taga (1992)
Science 258, 593-597
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Non-redundant Signal Transduction of Interleukin-6-type Cytokines. THE ADAPTER PROTEIN Shc IS SPECIFICALLY RECRUITED TO THE ONCOSTATIN M RECEPTOR.

H. M. Hermanns, S. Radtke, F. Schaper, P. C. Heinrich, and I. Behrmann (2000)
J. Biol. Chem. 275, 40742-40748
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