Science 28 February 1992: Vol. 255. no. 5048, pp. 1144 - 1147 DOI: 10.1126/science.1312258

Prev | Table of Contents | Next

Articles

Cyclin A-associated kinase activity is needed for paclitaxel sensitivity.

T. Takahashi, F. Yamasaki, T. Sudo, H. Itamochi, S. Adachi, M. Tamamori-Adachi, and N. T. Ueno (2005)
Mol. Cancer Ther. 4, 1039-1046
 |  Abstract »  |  Full Text »  |  PDF »

High-throughput RNAi screening in vitro: From cell lines to primary cells.

D. OVCHARENKO, R. JARVIS, S. HUNICKE-SMITH, K. KELNAR, and D. BROWN (2005)
RNA 11, 985-993
 |  Abstract »  |  Full Text »  |  PDF »

EAPP, a Novel E2F Binding Protein That Modulates E2F-dependent Transcription.

M. Novy, R. Pohn, P. Andorfer, T. Novy-Weiland, B. Galos, L. Schwarzmayr, and H. Rotheneder (2005)
Mol. Biol. Cell 16, 2181-2190
 |  Abstract »  |  Full Text »  |  PDF »

Cilostazol Inhibits Vascular Smooth Muscle Cell Growth by Downregulation of the Transcription Factor E2F.

M.-J. Kim, K.-G. Park, K.-M. Lee, H.-S. Kim, S.-Y. Kim, C.-S. Kim, S.-L. Lee, Y.-C. Chang, J.-Y. Park, K.-U. Lee, et al. (2005)
Hypertension 45, 552-556
 |  Abstract »  |  Full Text »  |  PDF »

Role of F-Box Protein {beta}Trcp1 in Mammary Gland Development and Tumorigenesis.

Y. Kudo, D. Guardavaccaro, P. G. Santamaria, R. Koyama-Nasu, E. Latres, R. Bronson, L. Yamasaki, and M. Pagano (2004)
Mol. Cell. Biol. 24, 8184-8194
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Induced Chemoresistance by Cotreatment with (E)-5-(2-Bromovinyl)-2'-Deoxyuridine (RP101).

R. Fahrig, J.-C. Heinrich, B. Nickel, F. Wilfert, C. Leisser, G. Krupitza, C. Praha, D. Sonntag, B. Fiedler, H. Scherthan, et al. (2003)
Cancer Res. 63, 5745-5753
 |  Abstract »  |  Full Text »  |  PDF »

MyoD Stimulates RB Promoter Activity via the CREB/p300 Nuclear Transduction Pathway.

A. Magenta, C. Cenciarelli, F. De Santa, P. Fuschi, F. Martelli, M. Caruso, and A. Felsani (2003)
Mol. Cell. Biol. 23, 2893-2906
 |  Abstract »  |  Full Text »  |  PDF »

Physical and Functional Interaction of HIV-1 Tat with E2F-4, a Transcriptional Regulator of Mammalian Cell Cycle.

C. Ambrosino, C. Palmieri, A. Puca, F. Trimboli, M. Schiavone, F. Olimpico, M. R. Ruocco, F. di Leva, M. Toriello, I. Quinto, et al. (2002)
J. Biol. Chem. 277, 31448-31458
 |  Abstract »  |  Full Text »  |  PDF »

Simian Immunodeficiency Virus Nef Protein Delays the Progression of CD4+ T Cells through G1/S Phase of the Cell Cycle.

T. Ndolo, N. K. Dhillon, H. Nguyen, M. Guadalupe, M. Mudryj, and S. Dandekar (2002)
J. Virol. 76, 3587-3595
 |  Abstract »  |  Full Text »  |  PDF »

Posttranscriptional Regulation of Cyclin A1 and Cyclin A2 During Mouse Oocyte Meiotic Maturation and Preimplantation Development.

D.-i. Fuchimoto, A. Mizukoshi, R. M. Schultz, S. Sakai, and F. Aoki (2001)
Biol Reprod 65, 986-993
 |  Abstract »  |  Full Text »  |  PDF »

Role of the F-Box Protein Skp2 in Adhesion-dependent Cell Cycle Progression.

A. C. Carrano and M. Pagano (2001)
J. Cell Biol. 153, 1381-1390
 |  Abstract »  |  Full Text »  |  PDF »

Gene Therapy for Attenuating Cardiac Allograft Arteriopathy Using Ex Vivo E2F Decoy Transfection by HVJ-AVE-Liposome Method in Mice and Nonhuman Primates.

M. Kawauchi, J.-i. Suzuki, R. Morishita, Y. Wada, A. Izawa, N. Tomita, J. Amano, Y. Kaneda, T. Ogihara, S. Takamoto, et al. (2000)
Circ. Res. 87, 1063-1068
 |  Abstract »  |  Full Text »  |  PDF »

Inducible pRb2/p130 Expression and Growth-suppressive Mechanisms: Evidence of a pRb2/p130, p27Kip1, and Cyclin E Negative Feedback Regulatory Loop.

C. M. Howard, P. P. Claudio, Antonio De Luca, P. Stiegler, F. P. Jori, N. M. Safdar, M. Caputi, K. Khalili, and A. Giordano (2000)
Cancer Res. 60, 2737-2744
 |  Abstract »  |  Full Text »

Increased proteasome degradation of cyclin-dependent kinase inhibitor p27 is associated with a decreased overall survival in mantle cell lymphoma.

R. Chiarle, L. M. Budel, J. Skolnik, G. Frizzera, M. Chilosi, A. Corato, G. Pizzolo, J. Magidson, A. Montagnoli, M. Pagano, et al. (2000)
Blood 95, 619-626
 |  Abstract »  |  Full Text »  |  PDF »

Adenoviral RB2/p130 Gene Transfer Inhibits Smooth Muscle Cell Proliferation and Prevents Restenosis After Angioplasty.

P. P. Claudio, L. Fratta, F. Farina, C. M. Howard, G. Stassi, S.-i. Numata, C. Pacilio, A. Davis, M. Lavitrano, M. Volpe, et al. (1999)
Circ. Res. 85, 1032-1039
 |  Abstract »  |  Full Text »  |  PDF »

The Phosphoenolpyruvate Carboxykinase Gene Glucocorticoid Response Unit: Identification of the Functional Domains of Accessory Factors HNF3{beta} (Hepatic Nuclear Factor-3{beta}) and HNF4 and the Necessity of Proper Alignment of Their Cognate Binding Sites.

J.-C. Wang, P.-E. Strömstedt, T. Sugiyama, and D. K. Granner (1999)
Mol. Endocrinol. 13, 604-618
 |  Abstract »  |  Full Text »

Application of Transcription Factor "Decoy" Strategy as Means of Gene Therapy and Study of Gene Expression in Cardiovascular Disease.

R. Morishita, J. Higaki, N. Tomita, and T. Ogihara (1998)
Circ. Res. 82, 1023-1028
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Growth of Human Vascular Smooth Muscle Cells by Overexpression of p21 Gene Through Induction of Apoptosis.

H. Matsushita, R. Morishita, I. Kida, M. Aoki, S.-i. Hayashi, N. Tomita, K. Yamamoto, A. Moriguchi, A. Noda, Y. Kaneda, et al. (1998)
Hypertension 31, 493-498
 |  Abstract »  |  Full Text »  |  PDF »

Distinct roles for E2F proteins in cell growth control and apoptosis.

J. DeGregori, G. Leone, A. Miron, L. Jakoi, and J. R. Nevins (1997)
PNAS 94, 7245-7250
 |  Abstract »  |  Full Text »  |  PDF »

Accumulation of E2F-4·DP-1 DNA Binding Complexes Correlates with Induction of dhfr Gene Expression during the G1 to S Phase Transition.

J. M. Wells, S. Illenye, J. Magae, C.-L. Wu, and N. H. Heintz (1997)
J. Biol. Chem. 272, 4483-4492
 |  Abstract »  |  Full Text »  |  PDF »

Role for Cyclin A-dependent Kinase in DNA Replication in Human S Phase Cell Extracts.

A. Fotedar, D. Cannella, P. Fitzgerald, T. Rousselle, S. Gupta, M. Doree, and R. Fotedar (1996)
J. Biol. Chem. 271, 31627-31637
 |  Abstract »  |  Full Text »  |  PDF »

Studies on the in Vitro Phosphorylation of HSSB-p34 and -p107 by Cyclin-dependent Kinases. CYCLIN-SUBSTRATE INTERACTIONS DICTATE THE EFFICIENCY OF PHOSPHORYLATION.

E. Gibbs, Z.-Q. Pan, H. Niu, and J. Hurwitz (1996)
J. Biol. Chem. 271, 22847-22854
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of Cyclin-dependent Kinase 5 (Cdk5) and Neuronal Cdk5 Activator in Bovine Brain.

K.-Y. Lee, J. L. Rosales, D. Tang, and J. H. Wang (1996)
J. Biol. Chem. 271, 1538-1543
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members.

J Magae, C. Wu, S Illenye, E Harlow, and N. Heintz (1996)
J. Cell Sci. 109, 1717-1726
 |  Abstract »  |  PDF »

Endoreduplication in Maize Endosperm: Involvement of M Phase--Promoting Factor Inhibition and Induction of S Phase--Related Kinases.

G. Grafi and B. A. Larkins (1995)
Science 269, 1262-1264
 |  Abstract »  |  PDF »

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27.

M Pagano, S. Tam, A. Theodoras, P Beer-Romero, G Del Sal, V Chau, P. Yew, G. Draetta, and M Rolfe (1995)
Science 269, 682-685
 |  Abstract »  |  PDF »

E2F-1 and a Cyclin-like DNA Repair Enzyme, Uracil-DNA Glycosylase, Provide Evidence for an Autoregulatory Mechanism for Transcription.

M. J. Walsh, G. Shue, K. Spidoni, and A. Kapoor (1995)
J. Biol. Chem. 270, 5289-5298
 |  Abstract »  |  Full Text »  |  PDF »

E2F-4, a new member of the E2F transcription factor family, interacts with p107..

D Ginsberg, G Vairo, T Chittenden, Z X Xiao, G Xu, K L Wydner, J A DeCaprio, J B Lawrence, and D M Livingston (1994)
Genes & Dev. 8, 2665-2679
 |  Abstract »  |  PDF »

Differential regulation of E2F transactivation by cyclin/cdk2 complexes..

B D Dynlacht, O Flores, J A Lees, and E Harlow (1994)
Genes & Dev. 8, 1772-1786
 |  Abstract »  |  PDF »

Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts..

M Pagano, A M Theodoras, S W Tam, and G F Draetta (1994)
Genes & Dev. 8, 1627-1639
 |  Abstract »  |  PDF »

Study of the higher eukaryotic gene function CDK2 using fission yeast.

J Paris, P Leplatois, and P Nurse (1994)
J. Cell Sci. 107, 615-623
 |  Abstract »  |  PDF »

The adenovirus E1A-associated 130-kD protein is encoded by a member of the retinoblastoma gene family and physically interacts with cyclins A and E..

Y Li, C Graham, S Lacy, A M Duncan, and P Whyte (1993)
Genes & Dev. 7, 2366-2377
 |  Abstract »  |  PDF »

Cell cycle-specific association of E2F with the p130 E1A-binding protein..

D Cobrinik, P Whyte, D S Peeper, T Jacks, and R A Weinberg (1993)
Genes & Dev. 7, 2392-2404
 |  Abstract »  |  PDF »

Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain..

M Hibi, A Lin, T Smeal, A Minden, and M Karin (1993)
Genes & Dev. 7, 2135-2148
 |  Abstract »  |  PDF »

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation..

Y Xiong, H Zhang, and D Beach (1993)
Genes & Dev. 7, 1572-1583
 |  Abstract »  |  PDF »

Negative regulation of G1 in mammalian cells: inhibition of cyclin E-dependent kinase by TGF-beta.

A Koff, M Ohtsuki, K Polyak, J. Roberts, and J Massague (1993)
Science 260, 536-539
 |  Abstract »  |  PDF »

Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4.

(1993)
Genes & Dev. 7, 331-342
 |  PDF »

Nuclear localization of vertebrate cyclin A correlates with its ability to form complexes with cdk catalytic subunits.

G Maridor, P Gallant, R Golsteyn, and E. Nigg (1993)
J. Cell Sci. 106, 535-544
 |  Abstract »  |  PDF »

Deregulation of cyclins D1 and E and suppression of cdk2 and cdk4 in senescent human fibroblasts.

F. Lucibello, A Sewing, S Brusselbach, C Burger, and R Muller (1993)
J. Cell Sci. 105, 123-133
 |  Abstract »  |  PDF »

Cyclin E/cdk2 and cyclin A/cdk2 kinases associate with p107 and E2F in a temporally distinct manner..

E Lees, B Faha, V Dulic, S I Reed, and E Harlow (1992)
Genes & Dev. 6, 1874-1885
 |  Abstract »  |  PDF »

To Advertise   |   Find Products