Science 31 January 1992: Vol. 255. no. 5044, pp. 603 - 606 DOI: 10.1126/science.1736363

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Articles

Endothelin-1 Couples {beta}Pix to p66Shc: Role of {beta}Pix in Cell Proliferation through FOXO3a Phosphorylation and p27kip1 Down-Regulation Independently of Akt.

A. Chahdi and A. Sorokin (2008)
Mol. Biol. Cell 19, 2609-2619
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New Insights into the Mechanisms of SOS Activation.

L. A. Quilliam (2007)
Sci. STKE 2007, pe67
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An Activating Mutation in sos-1 Identifies Its Dbl Domain as a Critical Inhibitor of the Epidermal Growth Factor Receptor Pathway during Caenorhabditis elegans Vulval Development.

K. Modzelewska, M. G. Elgort, J. Huang, G. Jongeward, A. Lauritzen, C. H. Yoon, P. W. Sternberg, and N. Moghal (2007)
Mol. Cell. Biol. 27, 3695-3707
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A Drosophila Model of Multiple Endocrine Neoplasia Type 2.

R. D. Read, P. J. Goodfellow, E. R. Mardis, N. Novak, J. R. Armstrong, and R. L. Cagan (2005)
Genetics 171, 1057-1081
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Drosophila PDZ-GEF, a Guanine Nucleotide Exchange Factor for Rap1 GTPase, Reveals a Novel Upstream Regulatory Mechanism in the Mitogen-Activated Protein Kinase Signaling Pathway.

J. H. Lee, K. S. Cho, J. Lee, D. Kim, S.-B. Lee, J. Yoo, G.-H. Cha, and J. Chung (2002)
Mol. Cell. Biol. 22, 7658-7666
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Targeted Disruption of Ras-Grf2 Shows Its Dispensability for Mouse Growth and Development.

A. Fernandez-Medarde, L. M. Esteban, A. Nunez, A. Porteros, L. Tessarollo, and E. Santos (2002)
Mol. Cell. Biol. 22, 2498-2504
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A Circadian Output in Drosophila Mediated by Neurofibromatosis-1 and Ras/MAPK.

J. A. Williams, H. S. Su, A. Bernards, J. Field, and A. Sehgal (2001)
Science 293, 2251-2256
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RotundRacGAP Functions with Ras during Spermatogenesis and Retinal Differentiation in Drosophila melanogaster.

E. Bergeret, I. Pignot-Paintrand, A. Guichard, K. Raymond, M.-O. Fauvarque, M. Cazemajor, and R. Griffin-Shea (2001)
Mol. Cell. Biol. 21, 6280-6291
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Ras-Guanine Nucleotide Exchange Factor Sos2 Is Dispensable for Mouse Growth and Development.

L. M. Esteban, A. Fernandez-Medarde, E. Lopez, K. Yienger, C. Guerrero, J. M. Ward, L. Tessarollo, and E. Santos (2000)
Mol. Cell. Biol. 20, 6410-6413
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Involvement of a Small GTP-binding Protein (G Protein) Regulator, Small G Protein GDP Dissociation Stimulator, in Antiapoptotic Cell Survival Signaling.

A. Takakura, J. Miyoshi, H. Ishizaki, M. Tanaka, A. Togawa, Y. Nishizawa, H. Yoshida, S.-i. Nishikawa, and Y. Takai (2000)
Mol. Biol. Cell 11, 1875-1886
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ZAP-70 Is Essential for the T Cell Antigen Receptor-induced Plasma Membrane Targeting of SOS and Vav in T Cells.

K. V. Salojin, J. Zhang, C. Meagher, and T. L. Delovitch (2000)
J. Biol. Chem. 275, 5966-5975
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The Properties of a tRNA-Specific Adenosine Deaminase from Drosophila melanogaster Support an Evolutionary Link between Pre-mRNA Editing and tRNA Modification.

L. P. Keegan, A. P. Gerber, J. Brindle, R. Leemans, A. Gallo, W. Keller, and M. A. O'Connell (2000)
Mol. Cell. Biol. 20, 825-833
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Calmodulin and son of sevenless dependent signaling pathways regulate midline crossing of axons in the Drosophila CNS.

J. Fritz and M. VanBerkum (2000)
Development 127, 1991-2000
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The tamas Gene, Identified as a Mutation That Disrupts Larval Behavior in Drosophila melanogaster, Codes for the Mitochondrial DNA Polymerase Catalytic Subunit (DNApol-{gamma}125).

B. Iyengar, J. Roote, and A. R. Campos (1999)
Genetics 153, 1809-1824
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An Exploration of the Sequence of a 2.9-Mb Region of the Genome of Drosophila melanogaster: The Adh Region.

M. Ashburner, S. Misra, J. Roote, S. E. Lewis, R. Blazej, T. Davis, C. Doyle, R. Galle, R. George, N. Harris, et al. (1999)
Genetics 153, 179-219
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Hematopoietic Growth Factors Signal Through the Formation of Reactive Oxygen Species.

M. Sattler, T. Winkler, S. Verma, C. H. Byrne, G. Shrikhande, R. Salgia, and J. D. Griffin (1999)
Blood 93, 2928-2935
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A Novel PDZ Domain Containing Guanine Nucleotide Exchange Factor Links Heterotrimeric G Proteins to Rho.

S. Fukuhara, C. Murga, M. Zohar, T. Igishi, and J. S. Gutkind (1999)
J. Biol. Chem. 274, 5868-5879
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Polyomavirus Large T Antigen Induces Alterations in Cytoplasmic Signalling Pathways Involving Shc Activation.

V. Gottifredi, G. Pelicci, E. Munarriz, R. Maione, P. G. Pelicci, and P. Amati (1999)
J. Virol. 73, 1427-1437
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Disabled Is a Putative Adaptor Protein That Functions during Signaling by the Sevenless Receptor Tyrosine Kinase.

N. Le and M. A. Simon (1998)
Mol. Cell. Biol. 18, 4844-4854
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N Terminus of Sos1 Ras Exchange Factor: Critical Roles for the Dbl and Pleckstrin Homology Domains.

X. Qian, W. C. Vass, A. G. Papageorge, P. H. Anborgh, and D. R. Lowy (1998)
Mol. Cell. Biol. 18, 771-778
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The 66-kDa Shc Isoform Is a Negative Regulator of the Epidermal Growth Factor-stimulated Mitogen-activated Protein Kinase Pathway.

S. Okada, A. W. Kao, B. P. Ceresa, P. Blaikie, B. Margolis, and J. E. Pessin (1997)
J. Biol. Chem. 272, 28042-28049
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Impaired Plasma Membrane Targeting of Grb2-Murine Son of Sevenless (mSOS) Complex and Differential Activation of the Fyn-T Cell Receptor (TCR)-{zeta}-Cbl Pathway Mediate T Cell Hyporesponsiveness in Autoimmune Nonobese Diabetic Mice.

K. Salojin, J. Zhang, M. Cameron, B. Gill, G. Arreaza, A. Ochi, and T. L. Delovitch (1997)
J. Exp. Med. 186, 887-897
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Mutation in Sos1 dominantly enhances a weak allele of the EGFR, demonstrating a requirement for Sos1 in EGFR signaling and development..

D Z Wang, V E Hammond, H E Abud, I Bertoncello, J W McAvoy, and D D Bowtell (1997)
Genes & Dev. 11, 309-320
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High Affinity Binding of the Pleckstrin Homology Domain of mSos1 to Phosphatidylinositol (4,5)-Bisphosphate.

T. J. Kubiseski, Y. M. Chook, W. E. Parris, M. Rozakis-Adcock, and T. Pawson (1997)
J. Biol. Chem. 272, 1799-1804
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The Drosophila 14-3-3 protein Leonardo enhances Torso signaling through D-Raf in a Ras 1-dependent manner.

W Li, E. Skoulakis, R. Davis, and N Perrimon (1997)
Development 124, 4163-4171
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Rin, a Neuron-Specific and Calmodulin-Binding Small G-Protein, and Rit Define a Novel Subfamily of Ras Proteins.

C.-H. J. Lee, N. G. Della, C. E. Chew, and D. J. Zack (1996)
J. Neurosci. 16, 6784-6794
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Ligation of the T-cell Antigen Receptor (TCR) Induces Association of hSos1, ZAP-70, Phospolipase C-[IMAGE]1, and Other Phosphoproteins with Grb2 and the [IMAGE]-Chain of the TCR.

AndrE. Nel, S. Gupta, L. Lee, J. A. Ledbetter, and S. B. Kanner (1995)
J. Biol. Chem. 270, 18428-18436
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In vivo functional analysis of the Ras exchange factor son of sevenless.

C. Karlovich, L Bonfini, L McCollam, R. Rogge, A Daga, M. Czech, and U Banerjee (1995)
Science 268, 576-579
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The role of yan in mediating the choice between cell division and differentiation.

R Rogge, P. Green, J Urano, S Horn-Saban, M Mlodzik, B. Shilo, V Hartenstein, and U Banerjee (1995)
Development 121, 3947-3958
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Characterization of Star and its interactions with sevenless and EGF receptor during photoreceptor cell development in Drosophila.

A. Kolodkin, A. Pickup, D. Lin, C. Goodman, and U Banerjee (1994)
Development 120, 1731-1745
 |  Abstract »  |  PDF »

Autosomal P[ovoD1] dominant female-sterile insertions in Drosophila and their use in generating germ-line chimeras.

T. B. Chou, E. Noll, and N. Perrimon (1993)
Development 119, 1359-1369
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Binding of the Ras activator son of sevenless to insulin receptor substrate-1 signaling complexes.

K Baltensperger, L. Kozma, A. Cherniack, J. Klarlund, A Chawla, U Banerjee, and M. Czech (1993)
Science 260, 1950-1952
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The function of GRB2 in linking the insulin receptor to Ras signaling pathways.

E. Skolnik, A Batzer, N Li, C. Lee, E Lowenstein, M Mohammadi, B Margolis, and J Schlessinger (1993)
Science 260, 1953-1955
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tramtrack is a transcriptional repressor required for cell fate determination in the Drosophila eye..

W C Xiong and C Montell (1993)
Genes & Dev. 7, 1085-1096
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The many roads that lead to Ras.

L. Feig (1993)
Science 260, 767-768
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Control of cell fate determination by p21ras/Ras1, an essential component of torso signaling in Drosophila..

X Lu, T B Chou, N G Williams, T Roberts, and N Perrimon (1993)
Genes & Dev. 7, 621-632
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Torso, a receptor tyrosine kinase required for embryonic pattern formation, shares substrates with the sevenless and EGF-R pathways in Drosophila..

H J Doyle and J M Bishop (1993)
Genes & Dev. 7, 633-646
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The strawberry notch gene functions with Notch in common developmental pathways.

C. Coyle-Thompson and U Banerjee (1993)
Development 119, 377-395
 |  Abstract »  |  PDF »

Ectopic expression of seven-up causes cell fate changes during ommatidial assembly.

Y Hiromi, M Mlodzik, S. West, G. Rubin, and C. Goodman (1993)
Development 118, 1123-1135
 |  Abstract »  |  PDF »

Expression and potential functions of G-protein alpha subunits in embryos of Xenopus laevis.

A. Otte, L. McGrew, J Olate, N. Nathanson, and R. Moon (1992)
Development 116, 141-146
 |  Abstract »  |  PDF »

Characterization of Drosophila Insulin Receptor Substrate.

R. M. K. Poltilove, A. R. Jacobs, C. R. Haft, P. Xu, and S. I. Taylor (2000)
J. Biol. Chem. 275, 23346-23354
 |  Abstract »  |  Full Text »  |  PDF »

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