Science 13 December 1991: Vol. 254. no. 5038, pp. 1643 - 1647 DOI: 10.1126/science.1840703

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Articles

The CD4+ T-Cell Response of Melanoma Patients to a MAGE-A3 Peptide Vaccine Involves Potential Regulatory T Cells.

V. Francois, S. Ottaviani, N. Renkvist, J. Stockis, G. Schuler, K. Thielemans, D. Colau, M. Marchand, T. Boon, S. Lucas, et al. (2009)
Cancer Res. 69, 4335-4345
 |  Abstract »  |  Full Text »  |  PDF »

Homo sapiens Lactate Dehydrogenase c (Ldhc) Gene Expression in Cancer Cells Is Regulated by Transcription Factor Sp1, CREB, and CpG Island Methylation.

H. Tang and E. Goldberg (2009)
J Androl 30, 157-167
 |  Abstract »  |  Full Text »  |  PDF »

Immunogenicity and Antitumor Effects of Vaccination with Peptide Vaccine +/- Granulocyte-Monocyte Colony-Stimulating Factor and/or IFN-{alpha}2b in Advanced Metastatic Melanoma: Eastern Cooperative Oncology Group Phase II Trial E1696.

J. M. Kirkwood, S. Lee, S. J. Moschos, M. R. Albertini, J. C. Michalak, C. Sander, T. Whiteside, L. H. Butterfield, and L. Weiner (2009)
Clin. Cancer Res. 15, 1443-1451
 |  Abstract »  |  Full Text »  |  PDF »

Recent Advances in Cancer Vaccines: An Overview.

K. Itoh, A. Yamada, T. Mine, and M. Noguchi (2009)
Jpn. J. Clin. Oncol. 39, 73-80
 |  Abstract »  |  Full Text »  |  PDF »

B7 Blockade Alters the Balance between Regulatory T Cells and Tumor-reactive T Cells for Immunotherapy of Cancer.

P. Zhou, X. Zheng, H. Zhang, Y. Liu, and P. Zheng (2009)
Clin. Cancer Res. 15, 960-970
 |  Abstract »  |  Full Text »  |  PDF »

CTdatabase: a knowledge-base of high-throughput and curated data on cancer-testis antigens.

L. G. Almeida, N. J. Sakabe, A. R. deOliveira, M. C. C. Silva, A. S. Mundstein, T. Cohen, Y.-T. Chen, R. Chua, S. Gurung, S. Gnjatic, et al. (2009)
Nucleic Acids Res. 37, D816-D819
 |  Abstract »  |  Full Text »  |  PDF »

Genome-wide analysis of cancer/testis gene expression.

O. Hofmann, O. L. Caballero, B. J. Stevenson, Y.-T. Chen, T. Cohen, R. Chua, C. A. Maher, S. Panji, U. Schaefer, A. Kruger, et al. (2008)
PNAS 105, 20422-20427
 |  Abstract »  |  Full Text »  |  PDF »

MELOE-1 is a new antigen overexpressed in melanomas and involved in adoptive T cell transfer efficiency.

Y. Godet, A. Moreau-Aubry, Y. Guilloux, V. Vignard, A. Khammari, B. Dreno, F. Jotereau, and N. Labarriere (2008)
J. Exp. Med. 205, 2673-2682
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Novel Tumor-Associated Antigen, Cadherin 3/P-Cadherin, as a Possible Target for Immunotherapy of Pancreatic, Gastric, and Colorectal Cancers.

K. Imai, S. Hirata, A. Irie, S. Senju, Y. Ikuta, K. Yokomine, M. Harao, M. Inoue, T. Tsunoda, S. Nakatsuru, et al. (2008)
Clin. Cancer Res. 14, 6487-6495
 |  Abstract »  |  Full Text »  |  PDF »

The Melanoma-Associated Antigen A3 Mediates Fibronectin-Controlled Cancer Progression and Metastasis.

W. Liu, S. Cheng, S. L. Asa, and S. Ezzat (2008)
Cancer Res. 68, 8104-8112
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Immune Responses and Clinical Efficacy in a Phase II Trial of IDM-2101, a 10-Epitope Cytotoxic T-Lymphocyte Vaccine, in Metastatic Non-Small-Cell Lung Cancer.

M. Barve, J. Bender, N. Senzer, C. Cunningham, F. A. Greco, D. McCune, R. Steis, H. Khong, D. Richards, J. Stephenson, et al. (2008)
J. Clin. Oncol. 26, 4418-4425
 |  Abstract »  |  Full Text »  |  PDF »

Implications of Aging and Self-Tolerance on the Generation of Immune and Antitumor Immune Responses.

A. L. Dominguez and J. Lustgarten (2008)
Cancer Res. 68, 5423-5431
 |  Abstract »  |  Full Text »  |  PDF »

Cancer Immunology.

O. J. Finn (2008)
N. Engl. J. Med. 358, 2704-2715
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Fibroblast Growth Factor 2 and Estrogen Control the Balance of Histone 3 Modifications Targeting MAGE-A3 in Pituitary Neoplasia.

X. Zhu, S. L. Asa, and S. Ezzat (2008)
Clin. Cancer Res. 14, 1984-1996
 |  Abstract »  |  Full Text »  |  PDF »

The Use of Filamentous Bacteriophage fd to Deliver MAGE-A10 or MAGE-A3 HLA-A2-Restricted Peptides and to Induce Strong Antitumor CTL Responses.

R. Sartorius, P. Pisu, L. D'Apice, L. Pizzella, C. Romano, G. Cortese, A. Giorgini, A. Santoni, F. Velotti, and P. De Berardinis (2008)
J. Immunol. 180, 3719-3728
 |  Abstract »  |  Full Text »  |  PDF »

SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade.

M. Fasso, R. Waitz, Y. Hou, T. Rim, N. M. Greenberg, N. Shastri, L. Fong, and J. P. Allison (2008)
PNAS 105, 3509-3514
 |  Abstract »  |  Full Text »  |  PDF »

Efficient Identification of a Novel Cancer/Testis Antigen for Immunotherapy Using Three-Step Microarray Analysis.

T. Yokoe, F. Tanaka, K. Mimori, H. Inoue, T. Ohmachi, M. Kusunoki, and M. Mori (2008)
Cancer Res. 68, 1074-1082
 |  Abstract »  |  Full Text »  |  PDF »

An Oncolytic Adenovirus Redirected with a Tumor-Specific T-Cell Receptor.

Z. Sebestyen, J. de Vrij, M. Magnusson, R. Debets, and R. Willemsen (2007)
Cancer Res. 67, 11309-11316
 |  Abstract »  |  Full Text »  |  PDF »

A Mycoplasma Peptide Elicits Heteroclitic CD4+ T Cell Responses against Tumor Antigen MAGE-A6.

L. Vujanovic, M. Mandic, W. C. Olson, J. M. Kirkwood, and W. J. Storkus (2007)
Clin. Cancer Res. 13, 6796-6806
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Novel Cancer-Testis Antigen CRT2 Frequently Expressed in Various Cancers Using Representational Differential Analysis.

E. Hayashi, Y. Matsuzaki, G. Hasegawa, T. Yaguchi, S. Kurihara, T. Fujita, T. Kageshita, M. Sano, and Y. Kawakami (2007)
Clin. Cancer Res. 13, 6267-6274
 |  Abstract »  |  Full Text »  |  PDF »

The Cancer/Testis Antigen Melanoma-Associated Antigen-A3/A6 Is a Novel Target of Fibroblast Growth Factor Receptor 2-IIIb through Histone H3 Modifications in Thyroid Cancer.

T. Kondo, X. Zhu, S. L. Asa, and S. Ezzat (2007)
Clin. Cancer Res. 13, 4713-4720
 |  Abstract »  |  Full Text »  |  PDF »

Identification and Characterization of ErbB-3-Binding Protein-1 as a Target for Immunotherapy.

S. J. A. M. Santegoets, M. W. J. Schreurs, A. W. Reurs, J. J. Lindenberg, E. W. M. Kueter, A. J. M. van den Eertwegh, E. Hooijberg, R. J. Brandwijk, S. E. Hufton, H. R. Hoogenboom, et al. (2007)
J. Immunol. 179, 2005-2012
 |  Abstract »  |  Full Text »  |  PDF »

Single mage gene in the chicken genome encodes CMage, a protein with functional similarities to mammalian type II Mage proteins.

N. Lopez-Sanchez, Z. Gonzalez-Fernandez, M. Niinobe, K. Yoshikawa, and J. M. Frade (2007)
Physiol Genomics 30, 156-171
 |  Abstract »  |  Full Text »  |  PDF »

Immunologic Approaches to Ovarian Cancer Treatment.

P. Sabbatini and K. Odunsi (2007)
J. Clin. Oncol. 25, 2884-2893
 |  Abstract »  |  Full Text »  |  PDF »

Chaperone-rich cell lysate embedded with BCR-ABL peptide demonstrates enhanced anti-tumor activity against a murine BCR-ABL positive leukemia.

K. L. Kislin, M. T. Marron, G. Li, M. W. Graner, and E. Katsanis (2007)
FASEB J 21, 2173-2184
 |  Abstract »  |  Full Text »  |  PDF »

Detection of MAGE-A Transcripts in Bone Marrow Is an Independent Prognostic Factor in Operable Non-Small-Cell Lung Cancer.

W. Sienel, I. Mecklenburg, S. Dango, P. Ehrhardt, A. Kirschbaum, B. Passlick, and K. Pantel (2007)
Clin. Cancer Res. 13, 3840-3847
 |  Abstract »  |  Full Text »  |  PDF »

Comparative Prime-Boost Vaccinations Using Semliki Forest Virus, Adenovirus, and ALVAC Vectors Demonstrate Differences in the Generation of a Protective Central Memory CTL Response against the P815 Tumor.

T. I. Naslund, C. Uyttenhove, E. K. L. Nordstrom, D. Colau, G. Warnier, M. Jondal, B. J. Van den Eynde, and P. Liljestrom (2007)
J. Immunol. 178, 6761-6769
 |  Abstract »  |  Full Text »  |  PDF »

CD8 tumor-infiltrating lymphocytes are predictive of survival in muscle-invasive urothelial carcinoma.

P. Sharma, Y. Shen, S. Wen, S. Yamada, A. A. Jungbluth, S. Gnjatic, D. F. Bajorin, V. E. Reuter, H. Herr, L. J. Old, et al. (2007)
PNAS 104, 3967-3972
 |  Abstract »  |  Full Text »  |  PDF »

Human Tumor Immunology at the Molecular Divide.

O. J. Finn (2007)
J. Immunol. 178, 2615-2616
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Unique Human Tumor Antigens: Immunobiology and Use in Clinical Trials.

G. Parmiani, A. De Filippo, L. Novellino, and C. Castelli (2007)
J. Immunol. 178, 1975-1979
 |  Abstract »  |  Full Text »  |  PDF »

CABYR Is a Novel Cancer-Testis Antigen in Lung Cancer.

C. Luo, X. Xiao, D. Liu, S. Chen, M. Li, A. Xu, J. Liu, S. Gao, S. Wu, and D. He (2007)
Clin. Cancer Res. 13, 1288-1297
 |  Abstract »  |  Full Text »  |  PDF »

Opa Interacting Protein 5 (OIP5) Is a Novel Cancer-testis Specific Gene in Gastric Cancer.

Y. Nakamura, F. Tanaka, H. Nagahara, K. Ieta, N. Haraguchi, K. Mimori, A. Sasaki, H. Inoue, K. Yanaga, and M. Mori (2007)
Ann. Surg. Oncol. 14, 885-892
 |  Abstract »  |  Full Text »  |  PDF »

Distorted Relation between mRNA Copy Number and Corresponding Major Histocompatibility Complex Ligand Density on the Cell Surface.

A. O. Weinzierl, C. Lemmel, O. Schoor, M. Muller, T. Kruger, D. Wernet, J. Hennenlotter, A. Stenzl, K. Klingel, H.-G. Rammensee, et al. (2007)
Mol. Cell. Proteomics 6, 102-113
 |  Abstract »  |  Full Text »  |  PDF »

Active Antiviral T-Lymphocyte Response Can Be Redirected against Tumor Cells by Antitumor Antibody x MHC/Viral Peptide Conjugates.

V. Cesson, K. Stirnemann, B. Robert, I. Luescher, T. Filleron, G. Corradin, J.-P. Mach, and A. Donda (2006)
Clin. Cancer Res. 12, 7422-7430
 |  Abstract »  |  Full Text »  |  PDF »

Immunotherapy for Renal Cell Cancer.

J. C. Yang and R. Childs (2006)
J. Clin. Oncol. 24, 5576-5583
 |  Abstract »  |  Full Text »  |  PDF »

Spontaneous CD8 T Cell Responses against the Melanocyte Differentiation Antigen RAB38/NY-MEL-1 in Melanoma Patients.

S. M. Walton, M. Gerlinger, O. de la Rosa, N. Nuber, A. Knights, A. Gati, M. Laumer, L. Strauss, C. Exner, N. Schafer, et al. (2006)
J. Immunol. 177, 8212-8218
 |  Abstract »  |  Full Text »  |  PDF »

Type, density, and location of immune cells within human colorectal tumors predict clinical outcome..

J. Galon, A. Costes, F. Sanchez-Cabo, A. Kirilovsky, B. Mlecnik, C. Lagorce-Pages, M. Tosolini, M. Camus, A. Berger, P. Wind, et al. (2006)
Science 313, 1960-1964
 |  Abstract »  |  Full Text »  |  PDF »

Cancer-Testis Antigens: Expression and Correlation with Survival in Human Urothelial Carcinoma..

P. Sharma, Y. Shen, S. Wen, D. F. Bajorin, V. E. Reuter, L. J. Old, and A. A. Jungbluth (2006)
Clin. Cancer Res. 12, 5442-5447
 |  Abstract »  |  Full Text »  |  PDF »

Unique Tumor Antigens: Evidence for Immune Control of Genome Integrity and Immunogenic Targets for T Cell-Mediated Patient-Specific Immunotherapy.

M. Sensi and A. Anichini (2006)
Clin. Cancer Res. 12, 5023-5032
 |  Abstract »  |  Full Text »  |  PDF »

MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents.

M. Monte, M. Simonatto, L. Y. Peche, D. R. Bublik, S. Gobessi, M. A. Pierotti, M. Rodolfo, and C. Schneider (2006)
PNAS 103, 11160-11165
 |  Abstract »  |  Full Text »  |  PDF »

Clinical and immunologic responses to active specific cancer vaccines in human colorectal cancer..

D. Nagorsen and E. Thiel (2006)
Clin. Cancer Res. 12, 3064-3069
 |  Abstract »  |  Full Text »  |  PDF »

Melanoma Antigen A4 Is Expressed in Non-Small Cell Lung Cancers and Promotes Apoptosis..

T. Peikert, U. Specks, C. Farver, S. C. Erzurum, and S. A.A. Comhair (2006)
Cancer Res. 66, 4693-4700
 |  Abstract »  |  Full Text »  |  PDF »

Agonist Anti-GITR Antibody Enhances Vaccine-Induced CD8+ T-Cell Responses and Tumor Immunity..

A. D. Cohen, A. Diab, M.-A. Perales, J. D. Wolchok, G. Rizzuto, T. Merghoub, D. Huggins, C. Liu, M. J. Turk, N. P. Restifo, et al. (2006)
Cancer Res. 66, 4904-4912
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a New Cancer/Germline Gene, KK-LC-1, Encoding an Antigen Recognized by Autologous CTL Induced on Human Lung Adenocarcinoma..

T. Fukuyama, T. Hanagiri, M. Takenoyama, Y. Ichiki, M. Mizukami, T. So, M. Sugaya, T. So, K. Sugio, and K. Yasumoto (2006)
Cancer Res. 66, 4922-4928
 |  Abstract »  |  Full Text »  |  PDF »

Promoter Demethylation and Histone Acetylation Mediate Gene Expression of MAGE-A1, -A2, -A3, and -A12 in Human Cancer Cells.

F. Wischnewski, K. Pantel, and H. Schwarzenbach (2006)
Mol. Cancer Res. 4, 339-349
 |  Abstract »  |  Full Text »  |  PDF »

Transient Down-regulation of DNMT1 Methyltransferase Leads to Activation and Stable Hypomethylation of MAGE-A1 in Melanoma Cells.

A. Loriot, E. De Plaen, T. Boon, and C. De Smet (2006)
J. Biol. Chem. 281, 10118-10126
 |  Abstract »  |  Full Text »  |  PDF »

An Inducible Mouse Model of Melanoma Expressing a Defined Tumor Antigen..

I. J. Huijbers, P. Krimpenfort, P. Chomez, M. A. van der Valk, J.-Y. Song, E.-M. Inderberg-Suso, A.-M. Schmitt-Verhulst, A. Berns, and B. J. Van den Eynde (2006)
Cancer Res. 66, 3278-3286
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Oncofetal Antigen/Immature Laminin Receptor Protein Epitopes That Activate BALB/c Mouse OFA/iLRP-Specific Effector and Regulatory T Cell Clones..

J. W. Rohrer, A. L. Barsoum, and J. H. Coggin Jr. (2006)
J. Immunol. 176, 2844-2856
 |  Abstract »  |  Full Text »  |  PDF »

Well-Defined Melanoma Antigens as Progression Markers for Melanoma: Insights into Differential Expression and Host Response Based on Stage.

F. S. Hodi (2006)
Clin. Cancer Res. 12, 673-678
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Expression of Synovial Sarcoma X (SSX) Antigens in Epithelial Ovarian Cancer and Identification of SSX-4 Epitopes Recognized by CD4+ T Cells.

D. Valmori, F. Qian, M. Ayyoub, C. Renner, A. Merlo, S. Gjnatic, E. Stockert, D. Driscoll, S. Lele, L. J. Old, et al. (2006)
Clin. Cancer Res. 12, 398-404
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Strategy for the Discovery of MHC Class II-Restricted Tumor Antigens: Identification of a Melanotransferrin Helper T-Cell Epitope.

T. A. Rohn, A. Reitz, A. Paschen, X. D. Nguyen, D. Schadendorf, A. B. Vogt, and H. Kropshofer (2005)
Cancer Res. 65, 10068-10078
 |  Abstract »  |  Full Text »  |  PDF »

Identification of an epitope derived from the cancer testis antigen HOM-TES-14/SCP1 and presented by dendritic cells to circulating CD4+ T cells.

F. Neumann, C. Wagner, K.-D. Preuss, B. Kubuschok, C. Schormann, S. Stevanovic, and M. Pfreundschuh (2005)
Blood 106, 3105-3113
 |  Abstract »  |  Full Text »  |  PDF »

Turning On/Off Tumor-Specific CTL Response during Progressive Tumor Growth.

Y. Huang, N. Obholzer, R. Fayad, and L. Qiao (2005)
J. Immunol. 175, 3110-3116
 |  Abstract »  |  Full Text »  |  PDF »

Immunogenic Targets in Non-Small Cell Lung Cancer: More Is More.

S. Gnjatic (2005)
Clin. Cancer Res. 11, 5331-5332
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Getting to the Surface: A Link Between Tumor Antigen Discovery and Natural Presentation of Peptide-MHC Complexes.

C. E. Clark and R. H. Vonderheide (2005)
Clin. Cancer Res. 11, 5333-5336
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Haplotype Loss of HLA Class I Antigen as an Escape Mechanism from Immune Attack in Lung Cancer.

T. So, M. Takenoyama, M. Mizukami, Y. Ichiki, M. Sugaya, T. Hanagiri, K. Sugio, and K. Yasumoto (2005)
Cancer Res. 65, 5945-5952
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Retargeting with MHC Class I-Restricted Antibodies: The CD28 Costimulatory Domain Enhances Antigen-Specific Cytotoxicity and Cytokine Production.

R. A. Willemsen, C. Ronteltap, P. Chames, R. Debets, and R. L. H. Bolhuis (2005)
J. Immunol. 174, 7853-7858
 |  Abstract »  |  Full Text »  |  PDF »

Rationale for Antiangiogenic Cancer Therapy with Vaccination Using Epitope Peptides Derived from Human Vascular Endothelial Growth Factor Receptor 2.

S. Wada, T. Tsunoda, T. Baba, F. J. Primus, H. Kuwano, M. Shibuya, and H. Tahara (2005)
Cancer Res. 65, 4939-4946
 |  Abstract »  |  Full Text »  |  PDF »

Frequent Immune Responses to a Cancer/Testis Antigen, CAGE, in Patients with Microsatellite instability-Positive Endometrial Cancer.

T. Iwata, T. Fujita, N. Hirao, Y. Matsuzaki, T. Okada, H. Mochimaru, N. Susumu, E. Matsumoto, K. Sugano, N. Yamashita, et al. (2005)
Clin. Cancer Res. 11, 3949-3957
 |  Abstract »  |  Full Text »  |  PDF »

Quantification of SSX mRNA Expression in Human Bone and Soft Tissue Tumors Using Nucleic Acid Sequence-Based Amplification.

N. Naka, S. Joyama, Y. Tsukamoto, K. Yoshioka, N. Hashimoto, T. Ujiiye, T. Hayashi, M. Kawase, M. Mano, S. Ishiguro, et al. (2005)
J. Mol. Diagn. 7, 187-197
 |  Abstract »  |  Full Text »  |  PDF »

Cancer/Testis Antigen Expression in Human Mesenchymal Stem Cells: Down-regulation of SSX Impairs Cell Migration and Matrix Metalloproteinase 2 Expression.

G. Cronwright, K. Le Blanc, C. Gotherstrom, P. Darcy, M. Ehnman, and B. Brodin (2005)
Cancer Res. 65, 2207-2215
 |  Abstract »  |  Full Text »  |  PDF »

Expression Profile of Cancer-Testis Genes in 121 Human Colorectal Cancer Tissue and Adjacent Normal Tissue.

M. Li, Y.-H. Yuan, Y. Han, Y.-X. Liu, L. Yan, Y. Wang, and J. Gu (2005)
Clin. Cancer Res. 11, 1809-1814
 |  Abstract »  |  Full Text »  |  PDF »

A Major Histocompatibility Complex{middle dot}Peptide-restricted Antibody and T Cell Receptor Molecules Recognize Their Target by Distinct Binding Modes: CRYSTAL STRUCTURE OF HUMAN LEUKOCYTE ANTIGEN (HLA)-A1{middle dot}MAGE-A1 IN COMPLEX WITH FAB-HYB3.

M. Hulsmeyer, P. Chames, R. C. Hillig, R. L. Stanfield, G. Held, P. G. Coulie, C. Alings, G. Wille, W. Saenger, B. Uchanska-Ziegler, et al. (2005)
J. Biol. Chem. 280, 2972-2980
 |  Abstract »  |  Full Text »  |  PDF »

Uveal and Cutaneous Melanoma: Shared Expression Characteristics of Melanoma-Associated Antigens.

L. C. van Dinten, N. Pul, A. F. van Nieuwpoort, C. J. Out, M. J. Jager, and P. J. van den Elsen (2005)
Invest. Ophthalmol. Vis. Sci. 46, 24-30
 |  Abstract »  |  Full Text »  |  PDF »

Ring Finger Protein 43 as a New Target for Cancer Immunotherapy.

N. Uchida, T. Tsunoda, S. Wada, Y. Furukawa, Y. Nakamura, and H. Tahara (2004)
Clin. Cancer Res. 10, 8577-8586
 |  Abstract »  |  Full Text »  |  PDF »

Mouse Homologue of a Novel Human Oncofetal Antigen, Glypican-3, Evokes T-Cell-Mediated Tumor Rejection without Autoimmune Reactions in Mice.

T. Nakatsura, H. Komori, T. Kubo, Y. Yoshitake, S. Senju, T. Katagiri, Y. Furukawa, M. Ogawa, Y. Nakamura, and Y. Nishimura (2004)
Clin. Cancer Res. 10, 8630-8640
 |  Abstract »  |  Full Text »  |  PDF »

Liposome-Encapsulated CpG Oligodeoxynucleotides as a Potent Adjuvant for Inducing Type 1 Innate Immunity.

Y. Suzuki, D. Wakita, K. Chamoto, Y. Narita, T. Tsuji, T. Takeshima, H. Gyobu, Y. Kawarada, S. Kondo, S. Akira, et al. (2004)
Cancer Res. 64, 8754-8760
 |  Abstract »  |  Full Text »  |  PDF »

The intensity of neutrophil infiltration controls the number of antigen-primed CD8 T cells recruited into cutaneous antigen challenge sites.

T. Engeman, A. V. Gorbachev, D. D. Kish, and R. L. Fairchild (2004)
J. Leukoc. Biol. 76, 941-949
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Cancer-Testis Antigen (CTA) Genes in Intrahepatic Cholangiocarcinoma.

T. Utsunomiya, H. Inoue, F. Tanaka, H. Yamaguchi, M. Ohta, M. Okamoto, K. Mimori, and M. Mori (2004)
Ann. Surg. Oncol. 11, 934-940
 |  Abstract »  |  Full Text »  |  PDF »

Response of Established Human Breast Tumors to Vaccination with Mammaglobin-A cDNA.

K. Narayanan, A. Jaramillo, N. D. Benshoff, L. G. Campbell, T. P. Fleming, J. R. Dietz, and T. Mohanakumar (2004)
J Natl Cancer Inst 96, 1388-1396
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Novel Human Cancer/Testis Antigen, KM-HN-1, Recognized by Cellular and Humoral Immune Responses.

M. Monji, T. Nakatsura, S. Senju, Y. Yoshitake, M. Sawatsubashi, M. Shinohara, T. Kageshita, T. Ono, A. Inokuchi, and Y. Nishimura (2004)
Clin. Cancer Res. 10, 6047-6057
 |  Abstract »  |  Full Text »  |  PDF »

Melanoma-Associated Antigens in Esophageal Adenocarcinoma: Identification of Novel MAGE-A10 Splice Variants.

J. Lin, L. Lin, D. G. Thomas, J. K. Greenson, T. J. Giordano, G. S. Robinson, R. A. Barve, F. A. Weishaar, J. M. G. Taylor, M. B. Orringer, et al. (2004)
Clin. Cancer Res. 10, 5708-5716
 |  Abstract »  |  Full Text »  |  PDF »

MAGE-A1 interacts with adaptor SKIP and the deacetylase HDAC1 to repress transcription.

S. Laduron, R. Deplus, S. Zhou, O. Kholmanskikh, D. Godelaine, C. De Smet, S. D. Hayward, F. Fuks, T. Boon, and E. De Plaen (2004)
Nucleic Acids Res. 32, 4340-4350
 |  Abstract »  |  Full Text »  |  PDF »

HER-2, gp100, and MAGE-1 Are Expressed in Human Glioblastoma and Recognized by Cytotoxic T Cells.

G. Liu, H. Ying, G. Zeng, C. J. Wheeler, K. L. Black, and J. S. Yu (2004)
Cancer Res. 64, 4980-4986
 |  Abstract »  |  Full Text »  |  PDF »

DNA Array-Based Gene Profiling in Tumor Immunology.

S. Mocellin, E. Wang, M. Panelli, P. Pilati, and F. M. Marincola (2004)
Clin. Cancer Res. 10, 4597-4606
 |  Abstract »  |  Full Text »  |  PDF »

Intratumoral CD8+ T Lymphocytes as a Prognostic Factor of Survival in Endometrial Carcinoma.

S. Kondratiev, E. Sabo, E. Yakirevich, O. Lavie, and M. B. Resnick (2004)
Clin. Cancer Res. 10, 4450-4456
 |  Abstract »  |  Full Text »  |  PDF »

Simultaneous Cellular and Humoral Immune Response against Mutated p53 in a Patient with Lung Cancer.

Y. Ichiki, M. Takenoyama, M. Mizukami, T. So, M. Sugaya, M. Yasuda, T. So, T. Hanagiri, K. Sugio, and K. Yasumoto (2004)
J. Immunol. 172, 4844-4850
 |  Abstract »  |  Full Text »  |  PDF »

A Cleaved Form of MAGE-A4 Binds to Miz-1 and Induces Apoptosis in Human Cells.

T. Sakurai, K. Itoh, H. Higashitsuji, T. Nagao, K. Nonoguchi, T. Chiba, and J. Fujita (2004)
J. Biol. Chem. 279, 15505-15514
 |  Abstract »  |  Full Text »  |  PDF »

Treatment of Melanoma with 5-Fluorouracil or Dacarbazine In Vitro Sensitizes Cells to Antigen-Specific CTL Lysis through Perforin/Granzyme- and Fas-Mediated Pathways.

S. Yang and F. G. Haluska (2004)
J. Immunol. 172, 4599-4608
 |  Abstract »  |  Full Text »  |  PDF »

NY-ESO-1 Expression and Immunogenicity in Malignant and Benign Breast Tumors.

Y. Sugita, H. Wada, S. Fujita, T. Nakata, S. Sato, Y. Noguchi, A. A. Jungbluth, M. Yamaguchi, Y.-T. Chen, E. Stockert, et al. (2004)
Cancer Res. 64, 2199-2204
 |  Abstract »  |  Full Text »  |  PDF »

DAMAGE, a Novel {alpha}-Dystrobrevin-associated MAGE Protein in Dystrophin Complexes.

D. E. Albrecht and S. C. Froehner (2004)
J. Biol. Chem. 279, 7014-7023
 |  Abstract »  |  Full Text »  |  PDF »

Generation and Targeting of Human Tumor-Specific Tc1 and Th1 Cells Transduced with a Lentivirus Containing a Chimeric Immunoglobulin T-Cell Receptor.

H. Gyobu, T. Tsuji, Y. Suzuki, T. Ohkuri, K. Chamoto, M. Kuroki, H. Miyoshi, Y. Kawarada, H. Katoh, T. Takeshima, et al. (2004)
Cancer Res. 64, 1490-1495
 |  Abstract »  |  Full Text »  |  PDF »

CD4+ T Cells Regulate CD8+ T Cell-Mediated Cutaneous Immune Responses by Restricting Effector T Cell Development through a Fas Ligand-Dependent Mechanism.

A. V. Gorbachev and R. L. Fairchild (2004)
J. Immunol. 172, 2286-2295
 |  Abstract »  |  Full Text »  |  PDF »

Identification of HLA-A24-Restricted CTL Epitope from Cancer-Testis Antigen, NY-ESO-1, and Induction of a Specific Antitumor Immune Response.

H. Yamaguchi, F. Tanaka, M. Ohta, H. Inoue, and M. Mori (2004)
Clin. Cancer Res. 10, 890-896
 |  Abstract »  |  Full Text »  |  PDF »

Humoral Responses to Peptides Correlate with Overall Survival in Advanced Cancer Patients Vaccinated with Peptides Based on Pre-existing, Peptide-Specific Cellular Responses.

T. Mine, Y. Sato, M. Noguchi, T. Sasatomi, R. Gouhara, N. Tsuda, S. Tanaka, H. Shomura, K. Katagiri, T. Rikimaru, et al. (2004)
Clin. Cancer Res. 10, 929-937
 |  Abstract »  |  Full Text »  |  PDF »

Complete response to donor lymphocyte infusion in multiple myeloma is associated with antibody responses to highly expressed antigens.

R. Bellucci, C. J. Wu, S. Chiaretti, E. Weller, F. E. Davies, E. P. Alyea, G. Dranoff, K. C. Anderson, N. C. Munshi, and J. Ritz (2004)
Blood 103, 656-663
 |  Abstract »  |  Full Text »  |  PDF »

Limited Gene Activation in Tumor and Normal Epithelial Cells Treated with the DNA Methyltransferase Inhibitor 5-Aza-2'-deoxycytidine.

A. R. Karpf, A. W. Lasek, T. O. Ririe, A. N. Hanks, D. Grossman, and D. A. Jones (2004)
Mol. Pharmacol. 65, 18-27
 |  Abstract »  |  Full Text »  |  PDF »

Phase I Trial of Large Multivalent Immunogen Derived from Melanoma Lysates in Patients with Disseminated Melanoma.

M. S. Mitchell, J. Kan-Mitchell, P. R. Morrow, D. Darrah, V. E. Jones, and M. F. Mescher (2004)
Clin. Cancer Res. 10, 76-83
 |  Abstract »  |  Full Text »  |  PDF »

Expression of the MAGE-A4 and NY-ESO-1 Cancer-Testis Antigens in Serous Ovarian Neoplasms.

E. Yakirevich, E. Sabo, O. Lavie, S. Mazareb, G. C. Spagnoli, and M. B. Resnick (2003)
Clin. Cancer Res. 9, 6453-6460
 |  Abstract »  |  Full Text »  |  PDF »

Proteasomal targeting of a viral oncogene abrogates oncogenic phenotype and enhances immunogenicity.

J. Tellam, G. Connolly, N. Webb, J. Duraiswamy, and R. Khanna (2003)
Blood 102, 4535-4540
 |  Abstract »  |  Full Text »  |  PDF »

Monoclonal Anti-MAGE-3 CTL Responses in Melanoma Patients Displaying Tumor Regression after Vaccination with a Recombinant Canarypox Virus.

V. Karanikas, C. Lurquin, D. Colau, N. van Baren, C. De Smet, B. Lethe, T. Connerotte, V. Corbiere, M.-A. Demoitie, D. Lienard, et al. (2003)
J. Immunol. 171, 4898-4904
 |  Abstract »  |  Full Text »  |  PDF »

Natural T Cell Immunity against Cancer.

D. Nagorsen, C. Scheibenbogen, F. M. Marincola, A. Letsch, and U. Keilholz (2003)
Clin. Cancer Res. 9, 4296-4303
 |  Abstract »  |  Full Text »  |  PDF »

Cooperative Effect between Immunotherapy and Antiangiogenic Therapy Leads to Effective Tumor Rejection in Tolerant Her-2/neu Mice.

C. Cuadros, A. L. Dominguez, G. I. Frost, P. Borgstrom, and J. Lustgarten (2003)
Cancer Res. 63, 5895-5901
 |  Abstract »  |  Full Text »  |  PDF »

NY-ESO-1 and LAGE-1 Cancer-Testis Antigens Are Potential Targets for Immunotherapy in Epithelial Ovarian Cancer.

K. Odunsi, A. A. Jungbluth, E. Stockert, F. Qian, S. Gnjatic, J. Tammela, M. Intengan, A. Beck, B. Keitz, D. Santiago, et al. (2003)
Cancer Res. 63, 6076-6083
 |  Abstract »  |  Full Text »  |  PDF »

The Receptor Tyrosine Kinase Ror2 Associates with the Melanoma-associated Antigen (MAGE) Family Protein Dlxin-1 and Regulates Its Intracellular Distribution.

T. Matsuda, H. Suzuki, I. Oishi, S. Kani, Y. Kuroda, T. Komori, A. Sasaki, K. Watanabe, and Y. Minami (2003)
J. Biol. Chem. 278, 29057-29064
 |  Abstract »  |  Full Text »  |  PDF »

Successful elimination of large established tumors and avoidance of antigen-loss variants by aggressive adoptive T cell immunotherapy.

K. Matsui, L. A. O'Mara, and P. M. Allen (2003)
Int. Immunol. 15, 797-805
 |  Abstract »  |  Full Text »  |  PDF »

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