Science 6 December 1991: Vol. 254. no. 5037, pp. 1497 - 1500 DOI: 10.1126/science.1962210

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Articles

Subnanomolar antisense activity of phosphonate-peptide nucleic acid (PNA) conjugates delivered by cationic lipids to HeLa cells.

T. Shiraishi, R. Hamzavi, and P. E. Nielsen (2008)
Nucleic Acids Res. 36, 4424-4432
 |  Abstract »  |  Full Text »  |  PDF »

Snap-to-it probes: chelate-constrained nucleobase oligomers with enhanced binding specificity.

J. R. Morgan, R. P. Lyon, D. Y. Maeda, and J. A. Zebala (2008)
Nucleic Acids Res. 36, 3522-3530
 |  Abstract »  |  Full Text »  |  PDF »

Purine twisted-intercalating nucleic acids: a new class of anti-gene molecules resistant to potassium-induced aggregation.

M. Paramasivam, S. Cogoi, V. V. Filichev, N. Bomholt, E. B. Pedersen, and L. E. Xodo (2008)
Nucleic Acids Res. 36, 3494-3507
 |  Abstract »  |  Full Text »  |  PDF »

'Protected DNA Probes' capable of strong hybridization without removal of base protecting groups.

A. Ohkubo, R. Kasuya, K. Sakamoto, K. Miyata, H. Taguchi, H. Nagasawa, T. Tsukahara, T. Watanobe, Y. Maki, K. Seio, et al. (2008)
Nucleic Acids Res. 36, 1952-1964
 |  Abstract »  |  Full Text »  |  PDF »

Chiral introduction of positive charges to PNA for double-duplex invasion to versatile sequences.

T. Ishizuka, J. Yoshida, Y. Yamamoto, J. Sumaoka, T. Tedeschi, R. Corradini, S. Sforza, and M. Komiyama (2008)
Nucleic Acids Res. 36, 1464-1471
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Imaging of bcl-2 Expression in Small Lymphocytic Lymphoma Using 111In-Labeled PNA-Peptide Conjugates.

F. Jia, S. D. Figueroa, F. Gallazzi, B. S. Balaji, M. Hannink, S. Z. Lever, T. J. Hoffman, and M. R. Lewis (2008)
J. Nucl. Med. 49, 430-438
 |  Abstract »  |  Full Text »  |  PDF »

Cell-Penetrating Peptide-Mediated Delivery of Peptide Nucleic Acid (PNA) Oligomers.

P. Lundberg, K. Kilk, and U. Langel (2008)
CSH Protocols 2008, pdb.prot4889
 |  Abstract »  |  Full Text »

Anti-gene padlocks eliminate Escherichia coli based on their genotype.

C. Shi, A. R. Parker, L. Hua, C. N. Morrell, S. C. Lee, V. Bandaru, J. S. Dumler, T. C. Wu, and J. R. Eshleman (2008)
J. Antimicrob. Chemother. 61, 262-272
 |  Abstract »  |  Full Text »  |  PDF »

A versatile method for the preparation of conjugates of peptides with DNA/PNA/analog by employing chemo-selective click reaction in water.

K. Gogoi, M. V. Mane, S. S. Kunte, and V. A. Kumar (2007)
Nucleic Acids Res. 35, e139
 |  Abstract »  |  Full Text »  |  PDF »

Site-directed gene mutation at mixed sequence targets by psoralen-conjugated pseudo-complementary peptide nucleic acids.

K.-H. Kim, P. E. Nielsen, and P. M. Glazer (2007)
Nucleic Acids Res. 35, 7604-7613
 |  Abstract »  |  Full Text »  |  PDF »

Development and Application of a Novel Peptide Nucleic Acid Probe for the Specific Detection of Helicobacter pylori in Gastric Biopsy Specimens.

N. Guimaraes, N. F. Azevedo, C. Figueiredo, C. W. Keevil, and M. J. Vieira (2007)
J. Clin. Microbiol. 45, 3089-3094
 |  Abstract »  |  Full Text »  |  PDF »

Cell-penetrating peptides as transporters for morpholino oligomers: effects of amino acid composition on intracellular delivery and cytotoxicity.

R. P. Wu, D. S. Youngblood, J. N. Hassinger, C. E. Lovejoy, M. H. Nelson, P. L. Iversen, and H. M. Moulton (2007)
Nucleic Acids Res.
 |  Abstract »  |  Full Text »  |  PDF »

Cellular antisense activity of peptide nucleic acid (PNAs) targeted to HIV-1 polypurine tract (PPT) containing RNA.

F. Boutimah-Hamoudi, E. Leforestier, C. Senamaud-Beaufort, P. E. Nielsen, C. Giovannangeli, and T. E. Saison-Behmoaras (2007)
Nucleic Acids Res. 35, 3907-3917
 |  Abstract »  |  Full Text »  |  PDF »

Nucleoside Phosphorylation by Phosphate Minerals.

G. Costanzo, R. Saladino, C. Crestini, F. Ciciriello, and E. Di Mauro (2007)
J. Biol. Chem. 282, 16729-16735
 |  Abstract »  |  Full Text »  |  PDF »

Zorro locked nucleic acid induces sequence-specific gene silencing.

R. Ge, J. E. Heinonen, M. G. Svahn, A. J. Mohamed, K. E. Lundin, and C. I. E. Smith (2007)
FASEB J 21, 1902-1914
 |  Abstract »  |  Full Text »  |  PDF »

On the stability of peptide nucleic acid duplexes in the presence of organic solvents.

A. Sen and P. E. Nielsen (2007)
Nucleic Acids Res. 35, 3367-3374
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Gene Expression and Growth by Antisense Peptide Nucleic Acids in a Multiresistant {beta}-Lactamase-Producing Klebsiella pneumoniae Strain.

P. Kurupati, K. S. W. Tan, G. Kumarasinghe, and C. L. Poh (2007)
Antimicrob. Agents Chemother. 51, 805-811
 |  Abstract »  |  Full Text »  |  PDF »

Orientation Preferences of Backbone Secondary Amide Functional Groups in Peptide Nucleic Acid Complexes: Quantum Chemical Calculations Reveal an Intrinsic Preference of Cationic D-Amino Acid-Based Chiral PNA Analogues for the P-form.

C. M. Topham and J. C. Smith (2007)
Biophys. J. 92, 769-786
 |  Abstract »  |  Full Text »  |  PDF »

Searching for somatic mutations in McCune-Albright syndrome: a comparative study of the peptidic nucleic acid versus the nested PCR method based on 148 DNA samples.

N Kalfa, P Philibert, F Audran, A Ecochard, T Hannon, S Lumbroso, and C Sultan (2006)
Eur. J. Endocrinol. 155, 839-843
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Apoptosis of Osteoclasts by Targeting Transcription Factors with Decoy Molecules.

R. PIVA, L. PENOLAZZI, M. ZENNARO, E. BIANCHINI, E. MAGRI, M. BORGATTI, I. LAMPRONTI, E. LAMBERTINI, E. TAVANTI, and R. GAMBARI (2006)
Ann. N.Y. Acad. Sci. 1091, 509-516
 |  Abstract »  |  Full Text »  |  PDF »

Structural diversity of target-specific homopyrimidine peptide nucleic acid-dsDNA complexes.

T. Bentin, G. I. Hansen, and P. E. Nielsen (2006)
Nucleic Acids Res. 34, 5790-5799
 |  Abstract »  |  Full Text »  |  PDF »

Utilising the left-helical conformation of L-DNA for analysing different marker types on a single universal microarray platform.

N. C. Hauser, R. Martinez, A. Jacob, S. Rupp, J. D. Hoheisel, and S. Matysiak (2006)
Nucleic Acids Res.
 |  Abstract »  |  Full Text »  |  PDF »

Targeting Species-Specific Low-Affinity 16S rRNA Binding Sites by Using Peptide Nucleic Acids for Detection of Legionellae in Biofilms.

S. A. Wilks and C. W. Keevil (2006)
Appl. Envir. Microbiol. 72, 5453-5462
 |  Abstract »  |  Full Text »  |  PDF »

Peptide Nucleic Acid-Based In Situ Hybridization Assay for Detection of Parvovirus B19 Nucleic Acids.

F. Bonvicini, C. Filippone, E. Manaresi, G. A. Gentilomi, M. Zerbini, M. Musiani, and G. Gallinella (2006)
Clin. Chem. 52, 973-978
 |  Abstract »  |  Full Text »  |  PDF »

Translocation of molecules into cells by pH-dependent insertion of a transmembrane helix.

Y. K. Reshetnyak, O. A. Andreev, U. Lehnert, and D. M. Engelman (2006)
PNAS 103, 6460-6465
 |  Abstract »  |  Full Text »  |  PDF »

In vivo identification of ribonucleoprotein-RNA interactions.

J. Zielinski, K. Kilk, T. Peritz, T. Kannanayakal, K. Y. Miyashiro, E. Eiriksdottir, J. Jochems, U. Langel, and J. Eberwine (2006)
PNAS 103, 1557-1562
 |  Abstract »  |  Full Text »  |  PDF »

Detection of rare mutant K-ras DNA in a single-tube reaction using peptide nucleic acid as both PCR clamp and sensor probe.

J.-D. Luo, E.-C. Chan, C.-L. Shih, T.-L. Chen, Y. Liang, T.-L. Hwang, and C.-C. Chiou (2006)
Nucleic Acids Res. 34, e12
 |  Abstract »  |  Full Text »  |  PDF »

Complementary base-pair-facilitated electron tunneling for electrically pinpointing complementary nucleobases.

T. Ohshiro and Y. Umezawa (2006)
PNAS 103, 10-14
 |  Abstract »  |  Full Text »  |  PDF »

Recognition of Chromosomal DNA in Human Cells by Peptide Nucleic Acids and Small Duplex RNAs.

D. R. COREY (2005)
Ann. N.Y. Acad. Sci. 1058, 16-25
 |  Abstract »  |  Full Text »  |  PDF »

Origin of Informational Polymers: DIFFERENTIAL STABILITY OF 3'- AND 5'-PHOSPHOESTER BONDS IN DEOXY MONOMERS AND OLIGOMERS.

R. Saladino, C. Crestini, V. Busiello, F. Ciciriello, G. Costanzo, and E. Di Mauro (2005)
J. Biol. Chem. 280, 35658-35669
 |  Abstract »  |  Full Text »  |  PDF »

End invasion of peptide nucleic acids (PNAs) with mixed-base composition into linear DNA duplexes.

I. V. Smolina, V. V. Demidov, V. A. Soldatenkov, S. G. Chasovskikh, and M. D. Frank-Kamenetskii (2005)
Nucleic Acids Res. 33, e146
 |  Abstract »  |  Full Text »  |  PDF »

Anti-HIV-1 activity of anti-TAR polyamide nucleic acid conjugated with various membrane transducing peptides.

S. Tripathi, B. Chaubey, S. Ganguly, D. Harris, R. A Casale, and V. N. Pandey (2005)
Nucleic Acids Res. 33, 4345-4356
 |  Abstract »  |  Full Text »  |  PDF »

Anti-gene peptide nucleic acid specifically inhibits MYCN expression in human neuroblastoma cells leading to cell growth inhibition and apoptosis.

R. Tonelli, S. Purgato, C. Camerin, R. Fronza, F. Bologna, S. Alboresi, M. Franzoni, R. Corradini, S. Sforza, A. Faccini, et al. (2005)
Mol. Cancer Ther. 4, 779-786
 |  Abstract »  |  Full Text »  |  PDF »

Sequential FISH analysis using competitive displacement of labelled peptide nucleic acid probes for eight chromosomes in human blastomeres.

I.E. Agerholm, S. Ziebe, B. Williams, C. Berg, D.G. Cruger, G. B. Petersen, and S. Kolvraa (2005)
Hum. Reprod. 20, 1072-1077
 |  Abstract »  |  Full Text »  |  PDF »

The Use of Peptide Nucleic Acids for In Situ Identification of Human Chromosomes.

F. Pellestor, P. Paulasova, M. Macek, and S. Hamamah (2005)
J. Histochem. Cytochem. 53, 395-400
 |  Abstract »  |  Full Text »  |  PDF »

Diagnosis of HNF-1{alpha} mutations on a PNA zip-code microarray by single base extension.

J. Y. Song, H. G. Park, S.-O. Jung, and J. Park (2005)
Nucleic Acids Res. 33, e19
 |  Abstract »  |  Full Text »  |  PDF »

Sequence-Selective Recognition of Extended-Spectrum {beta}-Lactamase GES-2 by a Competitive, Peptide Nucleic Acid-Based Multiplex PCR Assay.

G. F. Weldhagen (2004)
Antimicrob. Agents Chemother. 48, 3402-3406
 |  Abstract »  |  Full Text »  |  PDF »

The peptide nucleic acids: a new way for chromosomal investigation on isolated cells?.

F. Pellestor, P. Paulasova, M. Macek, and S. Hamamah (2004)
Hum. Reprod. 19, 1946-1951
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of MDR1 gene expression by chimeric HNA antisense oligonucleotides.

H. Kang, M. H. Fisher, D. Xu, Y. J. Miyamoto, A. Marchand, A. Van Aerschot, P. Herdewijn, and R. L. Juliano (2004)
Nucleic Acids Res. 32, 4411-4419
 |  Abstract »  |  Full Text »  |  PDF »

Intracellular inhibition of hepatitis C virus (HCV) internal ribosomal entry site (IRES)-dependent translation by peptide nucleic acids (PNAs) and locked nucleic acids (LNAs).

C. J. Nulf and D. Corey (2004)
Nucleic Acids Res. 32, 3792-3798
 |  Abstract »  |  Full Text »  |  PDF »

The peptide nucleic acids as probes for chromosomal analysis: application to human oocytes, polar bodies and preimplantation embryos.

P. Paulasova, B. Andreo, J. Diblik, M. Macek, and F. Pellestor (2004)
Mol. Hum. Reprod. 10, 467-472
 |  Abstract »  |  Full Text »  |  PDF »

Inducing and modulating anisotropic DNA bends by pseudocomplementary peptide nucleic acids.

H. Kuhn, D. I. Cherny, V. V. Demidov, and M. D. Frank-Kamenetskii (2004)
PNAS 101, 7548-7553
 |  Abstract »  |  Full Text »  |  PDF »

Localization and dynamics of small circular DNA in live mammalian nuclei.

G. Mearini, P. E. Nielsen, and F. O. Fackelmayer (2004)
Nucleic Acids Res. 32, 2642-2651
 |  Abstract »  |  Full Text »  |  PDF »

Specific versus Nonspecific Binding of Cationic PNAs to Duplex DNA.

A. Abibi, E. Protozanova, V. V. Demidov, and M. D. Frank-Kamenetskii (2004)
Biophys. J. 86, 3070-3078
 |  Abstract »  |  Full Text »  |  PDF »

A novel technique based on a PNA hybridization probe and FRET principle for quantification of mutant genotype in fibrous dysplasia/McCune-Albright syndrome.

A. Karadag, M. Riminucci, P. Bianco, N. Cherman, S. A. Kuznetsov, N. Nguyen, M. T. Collins, P. G. Robey, and L. W. Fisher (2004)
Nucleic Acids Res. 32, e63
 |  Abstract »  |  Full Text »  |  PDF »

Synthesis and Conformation Control of Peptide Ribonucleic Acid (PRNA) Containing 5'-Amino-5'-deoxyribopyrimidine and 5'-Amino-5'-deoxyribopurinenucleosides.

H. Sato, T. Wada, and Y. Inoue (2004)
Journal of Bioactive and Compatible Polymers 19, 65-79
 |  Abstract »  |  PDF »

Straightforward detection of SNPs in double-stranded DNA by using exonuclease III/nuclease S1/PNA system.

B. Ren, J.-M. Zhou, and M. Komiyama (2004)
Nucleic Acids Res. 32, e42
 |  Abstract »  |  Full Text »  |  PDF »

2'-O-[2-[(N,N-dimethylamino)oxy]ethyl]-modified oligonucleotides inhibit expression of mRNA in vitro and in vivo.

T. P. Prakash, J. F. Johnston, M. J. Graham, T. P. Condon, and M. Manoharan (2004)
Nucleic Acids Res. 32, 828-833
 |  Abstract »  |  Full Text »  |  PDF »

Borna Disease Virus Glycoprotein Is Required for Viral Dissemination in Neurons.

J. J. Bajramovic, S. Munter, S. Syan, U. Nehrbass, M. Brahic, and D. Gonzalez-Dunia (2003)
J. Virol. 77, 12222-12231
 |  Abstract »  |  Full Text »  |  PDF »

Insights into peptide nucleic acid (PNA) structural features: The crystal structure of a D-lysine-based chiral PNA-DNA duplex.

V. Menchise, G. De Simone, T. Tedeschi, R. Corradini, S. Sforza, R. Marchelli, D. Capasso, M. Saviano, and C. Pedone (2003)
PNAS 100, 12021-12026
 |  Abstract »  |  Full Text »  |  PDF »

PNA microarrays for hybridisation of unlabelled DNA samples.

O. Brandt, J. Feldner, A. Stephan, M. Schroder, M. Schnolzer, H. F. Arlinghaus, J. D. Hoheisel, and A. Jacob (2003)
Nucleic Acids Res. 31, e119
 |  Abstract »  |  Full Text »  |  PDF »

Intracellular Visualization of Prostate Cancer Using Magnetic Resonance Imaging.

S. Heckl, R. Pipkorn, W. Waldeck, H. Spring, J. Jenne, C.-W. von der Lieth, H. Corban-Wilhelm, J. Debus, and K. Braun (2003)
Cancer Res. 63, 4766-4772
 |  Abstract »  |  Full Text »  |  PDF »

Pseudocomplementary PNAs as selective modifiers of protein activity on duplex DNA: the case of type IIs restriction enzymes.

E. Protozanova, V. V. Demidov, P. E. Nielsen, and M. D. Frank-Kamenetskii (2003)
Nucleic Acids Res. 31, 3929-3935
 |  Abstract »  |  Full Text »  |  PDF »

Telomere Dynamics in Myelodysplastic Syndrome Determined by Telomere Measurement of Marrow Metaphases.

G. Sashida, J. H. Ohyashiki, A. Nakajima, M. Sumi, K. Kawakubo, T. Tauchi, and K. Ohyashiki (2003)
Clin. Cancer Res. 9, 1489-1496
 |  Abstract »  |  Full Text »  |  PDF »

Transcription Factor Decoy Molecules Based on a Peptide Nucleic Acid (PNA)-DNA Chimera Mimicking Sp1 Binding Sites.

M. Borgatti, I. Lampronti, A. Romanelli, C. Pedone, M. Saviano, N. Bianchi, C. Mischiati, and R. Gambari (2003)
J. Biol. Chem. 278, 7500-7509
 |  Abstract »  |  Full Text »  |  PDF »

Antiproliferative effect in chronic myeloid leukaemia cells by antisense peptide nucleic acids.

V. Rapozzi, B. E. A. Burm, S. Cogoi, G. A. van der Marel, J. H. van Boom, F. Quadrifoglio, and L. E. Xodo (2002)
Nucleic Acids Res. 30, 3712-3721
 |  Abstract »  |  Full Text »  |  PDF »

Profiling protein function with small molecule microarrays.

N. Winssinger, S. Ficarro, P. G. Schultz, and J. L. Harris (2002)
PNAS 99, 11139-11144
 |  Abstract »  |  Full Text »  |  PDF »

5'-,3'-Inverted Thymidine-modified Antisense Oligodeoxynucleotide Targeting Midkine. ITS DESIGN AND APPLICATION FOR CANCER THERAPY.

Y. Takei, K. Kadomatsu, H. Itoh, W. Sato, K. Nakazawa, S. Kubota, and T. Muramatsu (2002)
J. Biol. Chem. 277, 23800-23806
 |  Abstract »  |  Full Text »  |  PDF »

Kinetics and mechanism of the DNA double helix invasion by pseudocomplementary peptide nucleic acids.

V. V. Demidov, E. Protozanova, K. I. Izvolsky, C. Price, P. E. Nielsen, and M. D. Frank-Kamenetskii (2002)
PNAS 99, 5953-5958
 |  Abstract »  |  Full Text »  |  PDF »

Anti-TAR Polyamide Nucleotide Analog Conjugated with a Membrane-Permeating Peptide Inhibits Human Immunodeficiency Virus Type 1 Production.

N. Kaushik, A. Basu, P. Palumbo, R. L. Myers, and V. N. Pandey (2002)
J. Virol. 76, 3881-3891
 |  Abstract »  |  Full Text »  |  PDF »

Antisense Oligonucleotides: Basic Concepts and Mechanisms.

N. Dias and C. A. Stein (2002)
Mol. Cancer Ther. 1, 347-355
 |  Full Text »  |  PDF »

Cell Permeabilization and Uptake of Antisense Peptide-Peptide Nucleic Acid (PNA) into Escherichia coli.

M. Eriksson, P. E. Nielsen, and L. Good (2002)
J. Biol. Chem. 277, 7144-7147
 |  Abstract »  |  Full Text »  |  PDF »

In vitro transcription of a torsionally constrained template.

T. Bentin and P. E. Nielsen (2002)
Nucleic Acids Res. 30, 803-809
 |  Abstract »  |  Full Text »  |  PDF »

Triplex forming oligonucleotides: sequence-specific tools for gene targeting.

M. P. Knauert and P. M. Glazer (2001)
Hum. Mol. Genet. 10, 2243-2251
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear antisense effects of neutral, anionic and cationic oligonucleotide analogs.

P. Sazani, S.-H. Kang, M. A. Maier, C. Wei, J. Dillman, J. Summerton, M. Manoharan, and R. Kole (2001)
Nucleic Acids Res. 29, 3965-3974
 |  Abstract »  |  Full Text »  |  PDF »

Enhanced Expression of Endothelin B Receptor at Protein and Gene Levels in Human Cirrhotic Liver.

H. Yokomori, M. Oda, Y. Yasogawa, Y. Nishi, M. Ogi, M. Takahashi, and H. Ishii (2001)
Am. J. Pathol. 159, 1353-1362
 |  Abstract »  |  Full Text »

PNA interference mapping demonstrates functional domains in the noncoding RNA Xist.

A. Beletskii, Y.-K. Hong, J. Pehrson, M. Egholm, and W. M. Strauss (2001)
PNAS 98, 9215-9220
 |  Abstract »  |  Full Text »  |  PDF »

Solution structure of a DNA duplex with a chiral alkyl phosphonate moiety.

R. Soliva, V. Monaco, I. Gomez-Pinto, N. J. Meeuwenoord, G. A. V. d. Marel, J. H. V. Boom, C. Gonzalez, and M. Orozco (2001)
Nucleic Acids Res. 29, 2973-2985
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Promyelocytic Leukemia (PML)/Retinoic Acid Receptor-{alpha} and PML Expression in Acute Promyelocytic Leukemia Cells by Anti-PML Peptide Nucleic Acid.

L. Mologni, E. Marchesi, P. E. Nielsen, and C. Gambacorti-Passerini (2001)
Cancer Res. 61, 5468-5473
 |  Abstract »  |  Full Text »  |  PDF »

Telomere Length Dynamics in Normal Individuals and in Patients with Hematopoietic Stem Cell-Associated Disorders.

T. H. BRUMMENDORF, N. RUFER, T. L. HOLYOAKE, J. MACIEJEWSKI, M. J. BARNETT, C. J. EAVES, A. C. EAVES, N. YOUNG, and P. M. LANSDORP (2001)
Ann. N.Y. Acad. Sci. 938, 293-304
 |  Abstract »  |  Full Text »  |  PDF »

Evaluation of a Fluorescence In Situ Hybridization Assay for Differentiation between Tuberculous and Nontuberculous Mycobacterium Species in Smears of Lowenstein-Jensen and Mycobacteria Growth Indicator Tube Cultures Using Peptide Nucleic Acid Probes.

P. Hongmanee, H. Stender, and O. F. Rasmussen (2001)
J. Clin. Microbiol. 39, 1032-1035
 |  Abstract »  |  Full Text »

Antisense PNA effects in Escherichia coli are limited by the outer-membrane LPS layer.

L. Good, R. Sandberg, O. Larsson, P. E. Nielsen, and C. Wahlestedt (2000)
Microbiology 146, 2665-2670
 |  Abstract »  |  Full Text »

Strand invasion by mixed base PNAs and a PNA-peptide chimera.

X. Zhang, T. Ishihara, and D. R. Corey (2000)
Nucleic Acids Res. 28, 3332-3338
 |  Abstract »  |  Full Text »  |  PDF »

Affinity Purification of DNA and RNA from Environmental Samples with Peptide Nucleic Acid Clamps.

D. P. Chandler, J. R. Stults, S. Cebula, B. L. Schuck, D. W. Weaver, K. K. Anderson, M. Egholm, and F. J. Brockman (2000)
Appl. Envir. Microbiol. 66, 3438-3445
 |  Abstract »  |  Full Text »

Peptide nucleic acid (PNA): its medical and biotechnical applications and promise for the future.

A. RAY and B. NORDÉN (2000)
FASEB J 14, 1041-1060
 |  Abstract »  |  Full Text »

Identification of a Key Target Sequence To Block Human Immunodeficiency Virus Type 1 Replication within the gag-pol Transframe Domain.

S. Sei, Q.-e. Yang, D. O'Neill, K. Yoshimura, K. Nagashima, and H. Mitsuya (2000)
J. Virol. 74, 4621-4633
 |  Abstract »  |  Full Text »

Peptide nucleic acids rather than RNA may have been the first genetic molecule.

K. E. Nelson, M. Levy, and S. L. Miller (2000)
PNAS 97, 3868-3871
 |  Abstract »  |  Full Text »  |  PDF »

Dihydrotestosterone as a Selective Cellular/Nuclear Localization Vector for Anti-Gene Peptide Nucleic Acid in Prostatic Carcinoma Cells.

L. C. Boffa, S. Scarfi’, M. R. Mariani, G. Damonte, V. G. Allfrey, U. Benatti, and P. L. Morris (2000)
Cancer Res. 60, 2258-2262
 |  Abstract »  |  Full Text »

Antisense Inhibition of delta -Opioid Receptor Gene Function In Vivo by Peptide Nucleic Acids.

G. L. Fraser, J. Holmgren, P. B. S. Clarke, and C. Wahlestedt (2000)
Mol. Pharmacol. 57, 725-731
 |  Abstract »  |  Full Text »

Improved in situ detection method for telomeric tandem repeats in metaphase spreads and interphase nuclei.

V Uhlmann, M Prasad, I Silva, K Luettich, L Grande, L Alonso, M Thisted, K J Pluzek, J Gorst, M Ring, et al. (2000)
Mol. Pathol. 53, 48-50
 |  Abstract »  |  Full Text »

In Situ Hybridization of Prochlorococcus and Synechococcus (Marine Cyanobacteria) spp. with rRNA-Targeted Peptide Nucleic Acid Probes.

A. Z. Worden, S. W. Chisholm, and B. J. Binder (2000)
Appl. Envir. Microbiol. 66, 284-289
 |  Abstract »  |  Full Text »

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death.

B.-S. Herbert, A. E. Pitts, S. I. Baker, S. E. Hamilton, W. E. Wright, J. W. Shay, and D. R. Corey (1999)
PNAS 96, 14276-14281
 |  Abstract »  |  Full Text »  |  PDF »

Double duplex invasion by peptide nucleic acid: A general principle for sequence-specific targeting of double-stranded DNA.

J. Lohse, O. Dahl, and P. E. Nielsen (1999)
PNAS 96, 11804-11808
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Fluorescence In Situ Hybridization Assay Using Peptide Nucleic Acid Probes for Differentiation between Tuberculous and Nontuberculous Mycobacterium Species in Smears of Mycobacterium Cultures.

H. Stender, K. Lund, K. H. Petersen, O. F. Rasmussen, P. Hongmanee, H. Miörner, and S. E. Godtfredsen (1999)
J. Clin. Microbiol. 37, 2760-2765
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