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Science 6 December 1991:
Vol. 254. no. 5037, pp. 1491 - 1494
DOI: 10.1126/science.1962208
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Articles

Science, Vol 254, Issue 5037, 1491-1494
Copyright © 1991 by American Association for the Advancement of Science

articles

Symbiont recognition and subsequent morphogenesis as early events in an animal-bacterial mutualism

MJ McFall-Ngai and EG Ruby

Department of Biological Sciences, University of Southern California, Los Angeles 90089-0371.

Bacterial colonization of the developing light organ of the squid Euprymna scolopes is shown to be highly specific, with the establishment of a successful association resulting only when the juvenile host is exposed to seawater containing one of a subset of Vibrio fischeri strains. Before a symbiotic infection the organ has elaborate epithelial structures covered with cilia and microvilli that are involved in the transfer of bacteria to the incipient symbiotic tissue. These structures regressed within days following infection; however, they were retained in uninfected animals, suggesting that the initiation of symbiosis influences, and is perhaps a prerequisite for, the normal developmental program of the juvenile host.


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Symbiont-Induced Changes in Host Actin during the Onset of a Beneficial Animal-Bacterial Association.
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Population Dynamics of Vibrio fischeri during Infection of Euprymna scolopes.
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Dominance of Vibrio fischeri in Secreted Mucus outside the Light Organ of Euprymna scolopes: the First Site of Symbiont Specificity.
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The Squid-Vibrio Symbioses: From Demes to Genes.
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Contribution of pilA to Competitive Colonization of the Squid Euprymna scolopes by Vibrio fischeri.
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Roles of Vibrio fischeri and Nonsymbiotic Bacteria in the Dynamics of Mucus Secretion during Symbiont Colonization of the Euprymna scolopes Light Organ.
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Role for Phosphoglucomutase in Vibrio fischeri-Euprymna scolopes Symbiosis.
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J. Bacteriol. 184, 5121-5129
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Temperature Affects Species Distribution in Symbiotic Populations of Vibrio spp..
M. K. Nishiguchi (2000)
Appl. Envir. Microbiol. 66, 3550-3555
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LuxR- and Acyl-Homoserine-Lactone-Controlled Non-lux Genes Define a Quorum-Sensing Regulon in Vibrio fischeri.
S. M. Callahan and P. V. Dunlap (2000)
J. Bacteriol. 182, 2811-2822
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An Exclusive Contract: Specificity in the Vibrio fischeri-Euprymna scolopes Partnership.
K. L. Visick and M. J. McFall-Ngai (2000)
J. Bacteriol. 182, 1779-1787
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Competitive Dominance among Strains of Luminous Bacteria Provides an Unusual Form of Evidence for Parallel Evolution in Sepiolid Squid-Vibrio Symbioses.
M. K. Nishiguchi, E. G. Ruby, and M. J. McFall-Ngai (1998)
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Induction of a Gradual, Reversible Morphogenesis of Its Host's Epithelial Brush Border by Vibrio fischeri.
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A peroxidase related to the mammalian antimicrobial protein myeloperoxidase in the Euprymna-Vibrio mutualism.
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Circuit simulation of genetic networks.
H. McAdams and L Shapiro (1995)
Science 269, 650-656
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Bacterial symbionts induce host organ morphogenesis during early postembryonic development of the squid Euprymna scolopes.
M. Montgomery and M McFall-Ngai (1994)
Development 120, 1719-1729
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