Science 22 November 1991: Vol. 254. no. 5035, pp. 1138 - 1146 DOI: 10.1126/science.1659741

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Articles

Molecular Pathogenesis of Oral Squamous Cell Carcinoma: Implications for Therapy.

S. Choi and J.N. Myers (2008)
Journal of Dental Research 87, 14-32
 |  Abstract »  |  Full Text »  |  PDF »

Translating MicroRNA Discovery Into Clinical Biomarkers in Cancer.

S. A. Waldman and A. Terzic (2007)
JAMA 297, 1923-1925
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The Significance of c-erbB-2 Overexpression and p53 Expression in Patients With Axillary Lymph Node--Negative Breast Cancer: A Tissue Microarray Study.

S.-S. Ko, Y.-S. Na, C.-S. Yoon, J.-Y. Park, H.-S. Kim, M.-H. Hur, H.-K. Lee, Y.-K. Chun, S.-S. Kang, B.-W. Park, et al. (2007)
International Journal of Surgical Pathology 15, 98-109
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Cell Cycle Regulators p105, p107, Rb2/p130, E2F4, p21CIP1/WAF1, Cyclin A in Predicting Cervical Intraepithelial Neoplasia, High-Risk Human Papillomavirus Infections and Their Outcome in Women Screened in Three New Independent States of the Former Soviet Union..

R. Santopietro, I. Shabalova, N. Petrovichev, V. Kozachenko, T. Zakharova, J. Pajanidi, J. Podistov, G. Chemeris, L. Sozaeva, E. Lipova, et al. (2006)
Cancer Epidemiol. Biomarkers Prev. 15, 1250-1256
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Allelic Loss of the Gene for the GPX1 Selenium-Containing Protein Is a Common Event in Cancer.

Y. Hu, R. V. Benya, R. E. Carroll, and A. M. Diamond (2005)
J. Nutr. 135, 3021S-3024S
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Chromosomal instability and human cancer.

F. Michor (2005)
Phil Trans R Soc B 360, 631-635
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Chromosomal Instability in Oral Cancer Cells.

S.C. Reshmi and S.M. Gollin (2005)
Journal of Dental Research 84, 107-117
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Endometrial Glandular Dysplasia: A Putative Precursor Lesion of Uterine Papillary Serous Carcinoma. Part II: Molecular Features.

S. X. Liang, S. K. Chambers, L. Cheng, S. Zhang, Y. Zhou, and W. Zheng (2004)
International Journal of Surgical Pathology 12, 319-331
 |  Abstract »  |  PDF »

Evolutionary dynamics of tumor suppressor gene inactivation.

M. A. Nowak, F. Michor, N. L. Komarova, and Y. Iwasa (2004)
PNAS 101, 10635-10638
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The D5Mit7 locus on mouse chromosome 5 provides resistance to {gamma}-ray-induced but not N-methyl-N-nitrosourea-induced thymic lymphomas.

Y. Kodama, Y. Yoshikai, Y. Tamura, S. Wakana, R. Takagi, O. Niwa, and R. Kominami (2004)
Carcinogenesis 25, 143-148
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The linear process of somatic evolution.

M. A. Nowak, F. Michor, and Y. Iwasa (2003)
PNAS 100, 14966-14969
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Mouse Models to Study the Interaction of Risk Factors for Human Liver Cancer.

S. Sell (2003)
Cancer Res. 63, 7553-7562
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Loss of heterozygosity on the long arm of chromosome 21 in non-small cell lung cancer.

E. B. Lee, T. I. Park, S. H. Park, and J. Y. Park (2003)
Ann. Thorac. Surg. 75, 1597-1600
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Missing Expression of pRb2/p130 in Human Retinoblastomas Is Associated with Reduced Apoptosis and Lesser Differentiation.

C. Bellan, G. De Falco, G. M. Tosi, S. Lazzi, F. Ferrari, G. Morbini, S. Bartolomei, P. Toti, P. Mangiavacchi, G. Cevenini, et al. (2002)
Invest. Ophthalmol. Vis. Sci. 43, 3602-3608
 |  Abstract »  |  Full Text »  |  PDF »

Different genetic alterations in rat forestomach tumors induced by genotoxic and non-genotoxic carcinogens.

M. Kaneko, K. Morimura, T. Nishikawa, H. Wanibuchi, N. Takada, H. Osugi, H. Kinoshita, and S. Fukushima (2002)
Carcinogenesis 23, 1729-1735
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Carcinogenicity of dimethylarsinic acid in male F344 rats and genetic alterations in induced urinary bladder tumors.

M. Wei, H. Wanibuchi, K. Morimura, S. Iwai, K. Yoshida, G. Endo, D. Nakae, and S. Fukushima (2002)
Carcinogenesis 23, 1387-1397
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Classification of Colorectal Cancer Based on Chromosomal Loss and Microsatellite Instability Predicts Survival.

S.-W. Choi, K. J. Lee, Y.-A. Bae, K.-O. Min, M.-S. Kwon, K.-M. Kim, and M.-G. Rhyu (2002)
Clin. Cancer Res. 8, 2311-2322
 |  Abstract »  |  Full Text »  |  PDF »

Age-associated loss of heterozygosity of tumor suppressor genes in the gastric mucosa of humans.

L. Moragoda, R. Jaszewski, P. Kulkarni, and A. P. N. Majumdar (2002)
Am J Physiol Gastrointest Liver Physiol 282, G932-G936
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p21, p27 and p53 in estrogen and antiprogestin-induced tumor regression of experimental mouse mammary ductal carcinomas.

S. Vanzulli, A. Efeyan, F. Benavides, L. A. Helguero, G. Peters, J. Shen, C. J. Conti, C. Lanari, and A. Molinolo (2002)
Carcinogenesis 23, 749-758
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Combinations of the Variant Genotypes of GSTP1, GSTM1, and p53 Are Associated with an Increased Lung Cancer Risk.

D. P. Miller, G. Liu, I. De Vivo, T. J. Lynch, J. C. Wain, L. Su, and D. C. Christiani (2002)
Cancer Res. 62, 2819-2823
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Persistence of Tumor DNA in Plasma of Breast Cancer Patients After Mastectomy.

J. M. Silva, J. M. Garcia, G. Dominguez, J. Silva, C. Miralles, B. Cantos, S. Coca, M. Provencio, P. Espana, and F. Bonilla (2002)
Ann. Surg. Oncol. 9, 71-76
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Induction of cytostasis in mammary carcinoma cells treated with the anticancer agent perillyl alcohol.

W. Shi and M. N. Gould (2002)
Carcinogenesis 23, 131-142
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Genomic structure of the PIK3CG gene on chromosome band 7q22 and evaluation as a candidate myeloid tumor suppressor.

C. P. Kratz, B. M. Emerling, J. Bonifas, W. Wang, E. D. Green, M. M. L. Beau, and K. M. Shannon (2002)
Blood 99, 372-374
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Caveolin-1 Is Down-Regulated in Human Ovarian Carcinoma and Acts as a Candidate Tumor Suppressor Gene.

K. Wiechen, L. Diatchenko, A. Agoulnik, K. M. Scharff, H. Schober, K. Arlt, B. Zhumabayeva, P. D. Siebert, M. Dietel, R. Schafer, et al. (2001)
Am. J. Pathol. 159, 1635-1643
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Adeno-associated Virus for Cancer Gene Therapy.

S. Ponnazhagan, D. T. Curiel, D. R. Shaw, R. D. Alvarez, and G. P. Siegal (2001)
Cancer Res. 61, 6313-6321
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Who Is the Boss in the Retinoblastoma Family? The Point of View of Rb2/p130, the Little Brother.

M. G. Paggi and A. Giordano (2001)
Cancer Res. 61, 4651-4654
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Tumor Suppressor Protein p53 mRNA and Subcellular Localization Are Altered by Changes in Cellular Copper in Human Hep G2 Cells.

V. S. Narayanan, C. A. Fitch, and C. W. Levenson (2001)
J. Nutr. 131, 1427-1432
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Distribution and Functional Consequences of Nucleotide Polymorphisms in the 3'-Untranslated Region of the Human Sep15 Gene.

Y. Jun Hu, K. V. Korotkov, R. Mehta, D. L. Hatfield, C. N. Rotimi, A. Luke, T. E. Prewitt, R. S. Cooper, W. Stock, E. E. Vokes, et al. (2001)
Cancer Res. 61, 2307-2310
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Allelic imbalance on chromosomes 13 and 17 and mutation analysis of BRCA1 and BRCA2 genes in monozygotic twins concordant for breast cancer.

A. Forsti, L. Luo, I. Vorechovsky, M. Soderberg, P. Lichtenstein, and K. Hemminki (2001)
Carcinogenesis 22, 27-33
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Chromosome 11 allelotypes reflect a mechanism of chemical carcinogenesis in heterozygous p53-deficient mice.

J. E. Hulla, J. E. French, and J. K. Dunnick (2001)
Carcinogenesis 22, 89-98
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Neoplastic transformation of human osteoblast cells to the tumorigenic phenotype by heavy metal-tungsten alloy particles: induction of genotoxic effects.

A. C. Miller, S. Mog, L. McKinney, L. Luo, J. Allen, J. Xu, and N. Page (2001)
Carcinogenesis 22, 115-125
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The p53 Codon 72 Polymorphism and Lung Cancer Risk.

R. Fan, M.-T. Wu, D. Miller, J. C. Wain, K. T. Kelsey, J. K. Wiencke, and D. C. Christiani (2000)
Cancer Epidemiol. Biomarkers Prev. 9, 1037-1042
 |  Abstract »  |  Full Text »

Overexpression of Retinoblastoma Protein Predicts Decreased Survival and Correlates with Loss of p16INK4 Protein in Gallbladder Carcinomas.

Y.-Z. Shi, A.-M. Hui, X. Li, T. Takayama, and M. Makuuchi (2000)
Clin. Cancer Res. 6, 4096-4100
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Two Distinct Regions of Loss on Chromosome Arm 4q in Primary Head and Neck Squamous Cell Carcinoma.

S. I. Shah, L. Yip, B. Greenberg, J. A. Califano, J. Chow, C. F. Eisenberger, D. J. Lee, D. A. Sewell, A. L. Reed, M. Lango, et al. (2000)
Arch Otolaryngol Head Neck Surg 126, 1073-1076
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Cyclin D2 Overexpression in Transgenic Mice Induces Thymic and Epidermal Hyperplasia whereas Cyclin D3 Expression Results Only in Epidermal Hyperplasia.

M. L. Rodriguez-Puebla, M. LaCava, P. L. Miliani de Marval, J. L. Jorcano, E. R. Richie, and C. J. Conti (2000)
Am. J. Pathol. 157, 1039-1050
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Expression of a Retinoid-inducible Tumor Suppressor, Tazarotene-inducible Gene-3, Is Decreased in Psoriasis and Skin Cancer.

M. Duvic, B. Helekar, C. Schulz, M. Cho, D. DiSepio, C. Hager, D. DiMao, P. Hazarika, B. Jackson, J. Breuer-McHam, et al. (2000)
Clin. Cancer Res. 6, 3249-3259
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Stem Cell Factor Inhibits Erythroid Differentiation by Modulating the Activity of G1-Cyclin-dependent Kinase Complexes: A Role for p27 in Erythroid Differentiation Coupled G1 Arrest.

A. Tamir, T. Petrocelli, K. Stetler, W. Chu, J. Howard, B. St. Croix, J. Slingerland, and Y. Ben-David (2000)
Cell Growth Differ. 11, 269-277
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A Spontaneous Murine Melanoma Lung Metastasis Comprised of Host Tumor Hybrids.

A. K. Chakraborty, S. Sodi, M. Rachkovsky, N. Kolesnikova, J. T. Platt, J. L. Bolognia, and J. M. Pawelek (2000)
Cancer Res. 60, 2512-2519
 |  Abstract »  |  Full Text »

Molecular and Genetic Aspects of Lung Cancer.

W. N. ROM, J. G. HAY, T. C. LEE, Y. JIANG, and K.-M. TCHOU-WONG (2000)
Am. J. Respir. Crit. Care Med. 161, 1355-1367
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Definition and Refinement of Chromosome 8p Regions of Loss of Heterozygosity in Gastric Cancer.

R. Baffa, R. Santoro, F. Bullrich, B. Mandes, H. Ishii, and C. M. Croce (2000)
Clin. Cancer Res. 6, 1372-1377
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Characterization of the Murine Pituitary Tumor Transforming Gene (PTTG) and Its Promoter.

Z. Wang and S. Melmed (2000)
Endocrinology 141, 763-771
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Genetic Alterations Disrupting the Nuclear Localization of the Retinoblastoma-related Gene RB2/p130 in Human Tumor Cell Lines and Primary Tumors.

C. Cinti, P. P. Claudio, C. M. Howard, L. M. Neri, Y. Fu, L. Leoncini, G. M. Tosi, N. M. Maraldi, and A. Giordano (2000)
Cancer Res. 60, 383-389
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Recurrent alterations of the short arm of chromosome 3 define a tumor suppressor region in rat mammary tumor cells.

N. C. Popescu and J. W. Greiner (1999)
Carcinogenesis 20, 2033-2036
 |  Abstract »  |  Full Text »  |  PDF »

DNA Copy Number Losses in Human Neoplasms.

S. Knuutila, Y. Aalto, K. Autio, A.-M. Bjorkqvist, W.'e. El-Rifai, S. Hemmer, T. Huhta, E. Kettunen, S. Kiuru-Kuhlefelt, M. L. Larramendy, et al. (1999)
Am. J. Pathol. 155, 683-694
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Human Colon Cancer Cell Proliferation Mediated by the M3 Muscarinic Cholinergic Receptor.

H. Frucht, R. T. Jensen, D. Dexter, W.-L. Yang, and Y. Xiao (1999)
Clin. Cancer Res. 5, 2532-2539
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Altered dosage of the Saccharomyces cerevisiae spindle pole body duplication gene, NDC1, leads to aneuploidy and polyploidy.

H. J. Chial, T. H. Giddings Jr., E. A. Siewert, M. A. Hoyt, and M. Winey (1999)
PNAS 96, 10200-10205
 |  Abstract »  |  Full Text »  |  PDF »

Retinoic Acid Prevents Phosphorylation of pRB in Normal Human B Lymphocytes: Regulation of Cyclin E, Cyclin A, and p21Cip1.

S. Naderi and H. K. Blomhoff (1999)
Blood 94, 1348-1358
 |  Abstract »  |  Full Text »  |  PDF »

High Frequency and Heterogeneous Distribution of p53 Mutations in Aflatoxin B1-induced Mouse Lung Tumors.

A. S. Tam, J. F. Foley, T. R. Devereux, R. R. Maronpot, and T. E. Massey (1999)
Cancer Res. 59, 3634-3640
 |  Abstract »  |  Full Text »  |  PDF »

Frequent Loss of Expression of the Cyclin-dependent Kinase Inhibitor p27 in Epithelial Ovarian Cancer.

V. Masciullo, A. Sgambato, C. Pacilio, B. Pucci, G. Ferrandina, J. Palazzo, A. Carbone, A. Cittadini, S. Mancuso, G. Scambia, et al. (1999)
Cancer Res. 59, 3790-3794
 |  Abstract »  |  Full Text »  |  PDF »

C/EBPalpha Regulates Formation of S-Phase-Specific E2F-p107 Complexes in Livers of Newborn Mice.

N. A. Timchenko, M. Wilde, and G. J. Darlington (1999)
Mol. Cell. Biol. 19, 2936-2945
 |  Abstract »  |  Full Text »  |  PDF »

The FEZ1 gene at chromosome 8p22 encodes a leucine-zipper protein, and its expression is altered in multiple human tumors.

H. Ishii, R. Baffa, S.-I. Numata, Y. Murakumo, S. Rattan, H. Inoue, M. Mori, V. Fidanza, H. Alder, and C. M. Croce (1999)
PNAS 96, 3928-3933
 |  Abstract »  |  Full Text »  |  PDF »

Adenovirus mediated p53 tumour suppressor gene therapy for human gastric cancer cells in vitro and in vivo.

M Ohashi, F Kanai, H Ueno, T Tanaka, K Tateishi, T Kawakami, Y Koike, T Ikenoue, Y Shiratori, H Hamada, et al. (1999)
Gut 44, 366-371
 |  Abstract »  |  Full Text »  |  PDF »

Detailed Deletion Mapping of the Long Arm of Chromosome 6 in Adult T-Cell Leukemia.

Y. Hatta, Y. Yamada, M. Tomonaga, I. Miyoshi, J. W. Said, and H. P. Koeffler (1999)
Blood 93, 613-616
 |  Abstract »  |  Full Text »  |  PDF »

Rb Inhibits the Intrinsic Kinase Activity of TATA-Binding Protein-Associated Factor TAFII250.

J. L. Siegert and P. D. Robbins (1999)
Mol. Cell. Biol. 19, 846-854
 |  Abstract »  |  Full Text »  |  PDF »

Embryonic Lethality and Tumorigenesis Caused by Segmental Aneuploidy on Mouse Chromosome 11.

P. Liu, H. Zhang, A. McLellan, H. Vogel, and A. Bradley (1998)
Genetics 150, 1155-1168
 |  Abstract »  |  Full Text »

Chromosome Band 1p36 Contains a Putative Tumor Suppressor Gene Important in the Evolution of Chronic Myelocytic Leukemia.

N. Mori, R. Morosetti, S. Spira, S. Lee, D. Ben-Yehuda, G. Schiller, R. Landolfi, H. Mizoguchi, and H. P. Koeffler (1998)
Blood 92, 3405-3409
 |  Abstract »  |  Full Text »  |  PDF »

The Mitogen-Activated Protein Kinase Pathway Inhibits Ceramide-Induced Terminal Differentiation of a Human Monoblastic Leukemia Cell Line, U937.

S. J. Ragg, S. Kaga, K. A. Berg, and A. Ochi (1998)
J. Immunol. 161, 1390-1398
 |  Abstract »  |  Full Text »  |  PDF »

RB and c-Myc Activate Expression of the E-Cadherin Gene in Epithelial Cells through Interaction with Transcription Factor AP-2.

E. Batsché, C. Muchardt, J. Behrens, H. C. Hurst, and C. Crémisi (1998)
Mol. Cell. Biol. 18, 3647-3658
 |  Abstract »  |  Full Text »

Comparative Genomic Hybridization Analysis of Nonfunctioning Pituitary Tumors.

M. Daniely, A. Aviram, E. F. Adams, M. Buchfelder, G. Barkai, R. Fahlbusch, B. Goldman, and E. Friedman (1998)
J. Clin. Endocrinol. Metab. 83, 1801-1805
 |  Abstract »  |  Full Text »

Inactivation of p16 in Human Mammary Epithelial Cells by CpG Island Methylation.

S. A. Foster, D. J. Wong, M. T. Barrett, and D. A. Galloway (1998)
Mol. Cell. Biol. 18, 1793-1801
 |  Abstract »  |  Full Text »

Biology and Treatment of Childhood T-Lineage Acute Lymphoblastic Leukemia.

F. M. Uckun, M. G. Sensel, L. Sun, P. G. Steinherz, M. E. Trigg, N. A. Heerema, H. N. Sather, G. H. Reaman, and P. S. Gaynon (1998)
Blood 91, 735-746
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Necdin, A Postmitotic Neuron-specific Growth Suppressor, Interacts with Viral Transforming Proteins and Cellular Transcription Factor E2F1.

H. Taniura, N. Taniguchi, M. Hara, and K. Yoshikawa (1998)
J. Biol. Chem. 273, 720-728
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Myeloma: Increasing Evidence for a Multistep Transformation Process.

M. Hallek, P. Leif Bergsagel, and K. C. Anderson (1998)
Blood 91, 3-21
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RB and hbrm cooperate to repress the activation functions of E2F1.

D. Trouche, C. Le Chalony, C. Muchardt, M. Yaniv, and T. Kouzarides (1997)
PNAS 94, 11268-11273
 |  Abstract »  |  Full Text »  |  PDF »

Allelotype Analysis in the Evolution of Chronic Myelocytic Leukemia.

N. Mori, R. Morosetti, S. Lee, S. Spira, D. Ben-Yehuda, G. Schiller, R. Landolfi, H. Mizoguchi, and H. P. Koeffler (1997)
Blood 90, 2010-2014
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Proximal Element Mediates the Regulation of Mouse Ren-1C Promoter by Retinoblastoma Protein in Cultured Cells.

K. Tamura, S. Umemura, N. Nyui, S. Yamaguchi, T. Ishigami, K. Hibi, M. Yabana, M. Kihara, A. Fukamizu, K. Murakami, et al. (1997)
J. Biol. Chem. 272, 16845-16851
 |  Abstract »  |  Full Text »  |  PDF »

Homozygous Inactivation of the NF1 Gene in Bone Marrow Cells from Children with Neurofibromatosis Type 1 and Malignant Myeloid Disorders.

L. Side, B. Taylor, M. Cayouette, E. Conner, P. Thompson, M. Luce, and K. Shannon (1997)
N. Engl. J. Med. 336, 1713-1720
 |  Abstract »  |  Full Text »  |  PDF »

Altered Expression of the Retinoblastoma Tumor-Suppressor Gene in Leukemic Cell Lines Inhibits Induction of Differentiation But Not G1-Accumulation.

G. Bergh, M. Ehinger, T. Olofsson, B. Baldetorp, E. Johnsson, H. Brycke, G. Lindgren, I. Olsson, and U. Gullberg (1997)
Blood 89, 2938-2950
 |  Abstract »  |  Full Text »  |  PDF »

The cell cycle and cancer.

K. Collins, T. Jacks, and N. P. Pavletich (1997)
PNAS 94, 2776-2778
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Novel susceptibility locus for mouse hepatomas: evidence for a conserved tumor suppressor gene..

J C Zenklusen, L V Rodriguez, M LaCava, Z Wang, L S Goldstein, and C J Conti (1996)
Genome Res. 6, 1070-1076
 |  Abstract »  |  PDF »

MCC, a Cytoplasmic Protein That Blocks Cell Cycle Progression from the G(0)/G(1) to S Phase.

A. Matsumine, T. Senda, G.-H. Baeg, B. C. Roy, Y. Nakamura, M. Noda, K. Toyoshima, and T. Akiyama (1996)
J. Biol. Chem. 271, 10341-10346
 |  Abstract »  |  Full Text »  |  PDF »

70-kDa Heat Shock Cognate Protein Interacts Directly with the N-terminal Region of the Retinoblastoma Gene Product pRb.

A. Inoue, T. Torigoe, K. Sogahata, K. Kamiguchi, S. Takahashi, Y. Sawada, M. Saijo, Y. Taya, S.-i. Ishii, N. Sato, et al. (1995)
J. Biol. Chem. 270, 22571-22576
 |  Abstract »  |  Full Text »  |  PDF »

Effects of Tumor Necrosis Factor-alpha on Antimitogenicity and Cell Cycle-related Proteins in MCF-7 Cells.

D.-i. Jeoung, B. Tang, and M. Sonenberg (1995)
J. Biol. Chem. 270, 18367-18373
 |  Abstract »  |  Full Text »  |  PDF »

Inhibitors of mammalian G1 cyclin-dependent kinases..

C J Sherr and J M Roberts (1995)
Genes & Dev. 9, 1149-1163
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The Retinoblastoma Susceptibility Gene Product Represses Transcription When Directly Bound to the Promoter.

J. Adnane, Z. Shao, and P. D. Robbins (1995)
J. Biol. Chem. 270, 8837-8843
 |  Abstract »  |  Full Text »  |  PDF »

Binding of an Interferon-inducible Protein (p202) to the Retinoblastoma Protein.

D. Choubey and P. Lengyel (1995)
J. Biol. Chem. 270, 6134-6140
 |  Abstract »  |  Full Text »  |  PDF »

Positive and Negative Regulation of D-type Cyclin Expression in Skeletal Myoblasts by Basic Fibroblast Growth Factor and Transforming Growth Factor beta.

S. S. Rao and D. S. Kohtz (1995)
J. Biol. Chem. 270, 4093-4100
 |  Abstract »  |  Full Text »  |  PDF »

Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B.

M Santoro, F Carlomagno, A Romano, D. Bottaro, N. Dathan, M Grieco, A Fusco, G Vecchio, B Matoskova, M. Kraus, et al. (1995)
Science 267, 381-383
 |  Abstract »  |  PDF »

A tumor-associated glycosylation change in the glucose transporter GLUT1 controlled by tumor suppressor function in human cell hybrids.

T Kitagawa, Y Tsuruhara, M Hayashi, T Endo, and E. Stanbridge (1995)
J. Cell Sci. 108, 3735-3743
 |  Abstract »  |  PDF »

Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase.

T Xu, W Wang, S Zhang, R. Stewart, and W Yu (1995)
Development 121, 1053-1063
 |  Abstract »  |  PDF »

Collaboration of G1 cyclins in the functional inactivation of the retinoblastoma protein..

M Hatakeyama, J A Brill, G R Fink, and R A Weinberg (1994)
Genes & Dev. 8, 1759-1771
 |  Abstract »  |  PDF »

Reversal of terminal differentiation mediated by p107 in Rb-/- muscle cells.

J. Schneider, W Gu, L Zhu, V Mahdavi, and B Nadal-Ginard (1994)
Science 264, 1467-1471
 |  Abstract »  |  PDF »

The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein..

A Iavarone, P Garg, A Lasorella, J Hsu, and M A Israel (1994)
Genes & Dev. 8, 1270-1284
 |  Abstract »  |  PDF »

Loss of The Retinoblastoma Tumor-Suppressor Gene in Parathyroid Carcinoma.

V. L. Cryns, A. Thor, H.-J. Xu, S.-X. Hu, M. E. Wierman, A. L. Vickery, W. F. Benedict, and A. Arnold (1994)
N. Engl. J. Med. 330, 757-761
 |  Abstract »  |  Full Text »

Loss of The Normal NF1 Allele from the Bone Marrow of Children with Type 1 Neurofibromatosis and Malignant Myeloid Disorders.

K. M. Shannon, P. O'Connell, G. A. Martin, D. Paderanga, K. Olson, P. Dinndorf, and F. McCormick (1994)
N. Engl. J. Med. 330, 597-601
 |  Abstract »  |  Full Text »

The Molecular Basis of Leukemia.

M. J. Cline (1994)
N. Engl. J. Med. 330, 328-336
 |  Full Text »

Inhibition of myogenic differentiation in myoblasts expressing a truncated type II TGF-beta receptor.

E. Filvaroff, R Ebner, and R Derynck (1994)
Development 120, 1085-1095
 |  Abstract »  |  PDF »

Growth Suppression by Members of the Retinoblastoma Protein Family.

L. Zhu, G.H. Enders, C.-L. Wu, M.A. Starz, K.H. Moberg, J.A. Lees, N. Dyson, and E. Harlow (1994)
Cold Spring Harb Symp Quant Biol 59, 75-84
 |  Abstract »  |  PDF »

Studies of the Deleted in Colorectal Cancer Gene in Normal and Neoplastic Tissues.

E.R. Fearon, B.C. Ekstrand, G. Hu, W.E. Pierceall, M.A. Reale, and S.H. Bigner (1994)
Cold Spring Harb Symp Quant Biol 59, 637-643
 |  Abstract »  |  PDF »

The Clinical Applications of New DNA Diagnostic Technology on the Management of Cancer Patients.

J. D. Rowley, J. C. Aster, and J. Sklar (1993)
JAMA 270, 2331-2337
 |  Abstract »  |  PDF »

Neurofibromatosis Type 1: Beyond Positional Cloning.

D. H. Gutmann and F. S. Collins (1993)
Arch Neurol 50, 1185-1193
 |  Abstract »  |  PDF »

Molecular Screening: Prospects for a New Approach.

D. Sidransky, J. Boyle, and W. Koch (1993)
Arch Otolaryngol Head Neck Surg 119, 1187-1190
 |  Abstract »  |  PDF »

Molecular Genetic Analysis of the Mechanism of Tumorigenesis in Acoustic Neuroma.

R. M. Irving, D. A. Moffat, D. G. Hardy, D. E. Barton, J. H. Xuereb, and E. R. Maher (1993)
Arch Otolaryngol Head Neck Surg 119, 1222-1228
 |  Abstract »  |  PDF »

Clinical Implications of the p53 Tumor-Suppressor Gene.

C. C. Harris and M. Hollstein (1993)
N. Engl. J. Med. 329, 1318-1327
 |  Full Text »

The Role of the p53 Tumor Suppressor Gene in Squamous Cell Carcinoma of the Head and Neck.

J. K. Field, Z. P. Pavelic, D. A. Spandidos, P. J. Stambrook, A. S. Jones, and J. L. Gluckman (1993)
Arch Otolaryngol Head Neck Surg 119, 1118-1122
 |  Abstract »  |  PDF »

Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts..

D E Quelle, R A Ashmun, S A Shurtleff, J Y Kato, D Bar-Sagi, M F Roussel, and C J Sherr (1993)
Genes & Dev. 7, 1559-1571
 |  Abstract »  |  PDF »

Identification of the von Hippel-Lindau disease tumor suppressor gene.

F Latif, K Tory, J Gnarra, M Yao, F. Duh, M. Orcutt, T Stackhouse, I Kuzmin, W Modi, L Geil, et al. (1993)
Science 260, 1317-1320
 |  Abstract »  |  PDF »

Genetic mapping of a locus predisposing to human colorectal cancer.

P Peltomaki, L. Aaltonen, P Sistonen, L Pylkkanen, J. Mecklin, H Jarvinen, J. Green, Jass JR, J. Weber, F. Leach, et al. (1993)
Science 260, 810-812
 |  Abstract »  |  PDF »

Clues to the pathogenesis of familial colorectal cancer.

L. Aaltonen, P Peltomaki, F. Leach, P Sistonen, L Pylkkanen, J. Mecklin, H Jarvinen, S. Powell, J Jen, Hamilton SR, et al. (1993)
Science 260, 812-816
 |  Abstract »  |  PDF »

Inherited Breast and Ovarian Cancer: What Are the Risks? What Are the Choices?.

M.-C. King, S. Rowell, and S. M. Love (1993)
JAMA 269, 1975-1980
 |  Abstract »  |  PDF »

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