Science 15 November 1991: Vol. 254. no. 5034, pp. 1024 - 1026 DOI: 10.1126/science.1658941

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Articles

Structural Basis for Parathyroid Hormone-related Protein Binding to the Parathyroid Hormone Receptor and Design of Conformation-selective Peptides.

A. A. Pioszak, N. R. Parker, T. J. Gardella, and H. E. Xu (2009)
J. Biol. Chem. 284, 28382-28391
 |  Abstract »  |  Full Text »  |  PDF »

The Parathyroid Hormone 1 Receptor Directly Binds to the FERM Domain of Ezrin, an Interaction that Supports Apical Receptor Localization and Signaling in LLC-PK1 Cells.

M. J. Mahon (2009)
Mol. Endocrinol. 23, 1691-1701
 |  Abstract »  |  Full Text »  |  PDF »

Parathyroid Hormone Contributes to Regulating Milk Calcium Content and Modulates Neonatal Bone Formation Cooperatively with Calcium.

G. Cao, Z. Gu, Y. Ren, L. Shu, C. Tao, A. Karaplis, D. Goltzman, and D. Miao (2009)
Endocrinology 150, 561-569
 |  Abstract »  |  Full Text »  |  PDF »

Dexamethasone differentially regulates renal and duodenal calcium-processing genes in calbindin-D9k and -D28k knockout mice.

M.-H. Kim, G.-S. Lee, E.-M. Jung, K.-C. Choi, G.-T. Oh, and E.-B. Jeung (2009)
Exp Physiol 94, 138-151
 |  Abstract »  |  Full Text »  |  PDF »

Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways.

J. Y. Wu, L. E. Purton, S. J. Rodda, M. Chen, L. S. Weinstein, A. P. McMahon, D. T. Scadden, and H. M. Kronenberg (2008)
PNAS 105, 16976-16981
 |  Abstract »  |  Full Text »  |  PDF »

Parathyroid hormone signaling through low-density lipoprotein-related protein 6.

M. Wan, C. Yang, J. Li, X. Wu, H. Yuan, H. Ma, X. He, S. Nie, C. Chang, and X. Cao (2008)
Genes & Dev. 22, 2968-2979
 |  Abstract »  |  Full Text »  |  PDF »

Selective coupling of type 6 adenylyl cyclase with type 2 IP3 receptors mediates direct sensitization of IP3 receptors by cAMP.

S. C. Tovey, S. G. Dedos, E. J.A. Taylor, J. E. Church, and C. W. Taylor (2008)
J. Cell Biol. 183, 297-311
 |  Abstract »  |  Full Text »  |  PDF »

Negative Regulation of the Osteoblast Function in Multiple Myeloma through the Repressor Gene E4BP4 Activated by Malignant Plasma Cells.

F. Silvestris, P. Cafforio, M. De Matteo, N. Calvani, M. A. Frassanito, and F. Dammacco (2008)
Clin. Cancer Res. 14, 6081-6091
 |  Abstract »  |  Full Text »  |  PDF »

Negative Regulation of Parathyroid Hormone (PTH)-Activated Phospholipase C by PTH/PTH-Related Peptide Receptor Phosphorylation and Protein Kinase A.

H. A. W. Tawfeek and A. B. Abou-Samra (2008)
Endocrinology 149, 4016-4023
 |  Abstract »  |  Full Text »  |  PDF »

Molecular recognition of parathyroid hormone by its G protein-coupled receptor.

A. A. Pioszak and H. E. Xu (2008)
PNAS 105, 5034-5039
 |  Abstract »  |  Full Text »  |  PDF »

PTH-Related Peptide (PTHrP) in Hypercalcemia.

G. R. Mundy and J. R. Edwards (2008)
J. Am. Soc. Nephrol. 19, 672-675
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-18 Is Regulated by Parathyroid Hormone and Is Required for Its Bone Anabolic Actions.

L. J. Raggatt, L. Qin, J. Tamasi, S. C. Jefcoat Jr., E. Shimizu, N. Selvamurugan, F. Y. Liew, L. Bevelock, J. H. M. Feyen, and N. C. Partridge (2008)
J. Biol. Chem. 283, 6790-6798
 |  Abstract »  |  Full Text »  |  PDF »

Parathyroid hormone stimulates the endothelial nitric oxide synthase through protein kinase A and C pathways.

G. Rashid, J. Bernheim, J. Green, and S. Benchetrit (2007)
Nephrol. Dial. Transplant. 22, 2831-2837
 |  Abstract »  |  Full Text »  |  PDF »

BMP4 and PTHrP interact to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction.

J. R. Hens, P. Dann, J.-P. Zhang, S. Harris, G. W. Robinson, and J. Wysolmerski (2007)
Development 134, 1221-1230
 |  Abstract »  |  Full Text »  |  PDF »

Endothelin and calciotropic hormones share regulatory pathways in multidrug resistance protein 2-mediated transport.

K. E. Wever, R. Masereeuw, D. S. Miller, X. M. Hang, and G. Flik (2007)
Am J Physiol Renal Physiol 292, F38-F46
 |  Abstract »  |  Full Text »  |  PDF »

Impact of Impaired Receptor Internalization on Calcium Homeostasis in Knock-In Mice Expressing a Phosphorylation-Deficient Parathyroid Hormone (PTH)/PTH-Related Peptide Receptor.

G. S. Bounoutas, H. Tawfeek, L. F. Frohlich, U.-i. Chung, and A. B. Abou-Samra (2006)
Endocrinology 147, 4674-4679
 |  Abstract »  |  Full Text »  |  PDF »

Parathyroid Hormone-related Protein Regulates Tumor-relevant Genes in Breast Cancer Cells.

A. Dittmer, M. Vetter, D. Schunke, P. N. Span, F. Sweep, C. Thomssen, and J. Dittmer (2006)
J. Biol. Chem. 281, 14563-14572
 |  Abstract »  |  Full Text »  |  PDF »

Coding GNAS Mutations Leading to Hormone Resistance Impair in Vitro Agonist- and Cholera Toxin-Induced Adenosine Cyclic 3',5'-Monophosphate Formation Mediated by Human XL{alpha}s.

A. Linglart, M. J. Mahon, M. A. Kerachian, D. M. Berlach, G. N. Hendy, H. Juppner, and M. Bastepe (2006)
Endocrinology 147, 2253-2262
 |  Abstract »  |  Full Text »  |  PDF »

Distinct beta-Arrestin- and G Protein-dependent Pathways for Parathyroid Hormone Receptor-stimulated ERK1/2 Activation.

D. Gesty-Palmer, M. Chen, E. Reiter, S. Ahn, C. D. Nelson, S. Wang, A. E. Eckhardt, C. L. Cowan, R. F. Spurney, L. M. Luttrell, et al. (2006)
J. Biol. Chem. 281, 10856-10864
 |  Abstract »  |  Full Text »  |  PDF »

Cloning of the Chicken Pituitary Receptor for Growth Hormone-Releasing Hormone.

A. A. Toogood, S. Harvey, M. O. Thorner, and B. D. Gaylinn (2006)
Endocrinology 147, 1838-1846
 |  Abstract »  |  Full Text »  |  PDF »

Parathyroid hormone: past and present.

J. T Potts (2005)
J. Endocrinol. 187, 311-325
 |  Abstract »  |  Full Text »  |  PDF »

Turn-on switch in parathyroid hormone receptor by a two-step parathyroid hormone binding mechanism.

M. Castro, V. O. Nikolaev, D. Palm, M. J. Lohse, and J.-P. Vilardaga (2005)
PNAS 102, 16084-16089
 |  Abstract »  |  Full Text »  |  PDF »

Hypercalcaemia of malignancy and basic research on mechanisms responsible for osteolytic and osteoblastic metastasis to bone.

G A Clines and T A Guise (2005)
Endocr. Relat. Cancer 12, 549-583
 |  Abstract »  |  Full Text »  |  PDF »

Magic Bullets to Kill Nasty Osteoclasts.

S. Khosla (2005)
Endocrinology 146, 3233-3234
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Parathyroid Hormone-related Peptide (hPTHrP) and Parathyroid Hormone-related Peptide Receptor Type 1 (PTHR1) Expression in Human Thymus.

M. Gessi, G. Monego, L. Lauriola, N. Maggiano, and F. O. Ranelletti (2005)
J. Histochem. Cytochem. 53, 955-962
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Parathyroid Hormone-Related Peptide by Estradiol: Effect on Tumor Growth and Metastasis in Vitro and in Vivo.

S. A. Rabbani, P. Khalili, A. Arakelian, H. Pizzi, G. Chen, and D. Goltzman (2005)
Endocrinology 146, 2885-2894
 |  Abstract »  |  Full Text »  |  PDF »

Backbone-methylated Analogues of the Principle Receptor Binding Region of Human Parathyroid Hormone: EVIDENCE FOR BINDING TO BOTH THE N-TERMINAL EXTRACELLULAR DOMAIN AND EXTRACELLULAR LOOP REGION.

J.-R. Barbier, T. J. Gardella, T. Dean, S. MacLean, Z. Potetinova, J. F. Whitfield, and G. E. Willick (2005)
J. Biol. Chem. 280, 23771-23777
 |  Abstract »  |  Full Text »  |  PDF »

Isogenic Human Cell Lines for Drug Discovery: Regulation of Target Gene Expression by Engineered Zinc-Finger Protein Transcription Factors.

P.-Q. Liu, S. Tan, M. C. Mendel, R. J. Murrills, B. M. Bhat, B. Schlag, R. Samuel, J. J. Matteo, R. de la Rosa, K. Howes, et al. (2005)
J Biomol Screen 10, 304-313
 |  Abstract »  |  PDF »

Increased Renal Calcium Reabsorption by Parathyroid Hormone-Related Protein Is a Causative Factor in the Development of Humoral Hypercalcemia of Malignancy Refractory to Osteoclastic Bone Resorption Inhibitors.

E. Onuma, Y. Azuma, H. Saito, T. Tsunenari, T. Watanabe, M. Hirabayashi, K. Sato, H. Yamada-Okabe, and E. Ogata (2005)
Clin. Cancer Res. 11, 4198-4203
 |  Abstract »  |  Full Text »  |  PDF »

The Receptor for Parathyroid Hormone and Parathyroid Hormone-Related Peptide Is Hydrolyzed and Its Signaling Properties Are Altered by Directly Binding the Calpain Small Subunit.

M. Shimada, M. J. Mahon, P. A. Greer, and G. V. Segre (2005)
Endocrinology 146, 2336-2344
 |  Abstract »  |  Full Text »  |  PDF »

Parathyroid Hormone Receptor Trafficking Contributes to the Activation of Extracellular Signal-regulated Kinases but Is Not Required for Regulation of cAMP Signaling.

C. A. Syme, P. A. Friedman, and A. Bisello (2005)
J. Biol. Chem. 280, 11281-11288
 |  Abstract »  |  Full Text »  |  PDF »

Amphiregulin Is a Novel Growth Factor Involved in Normal Bone Development and in the Cellular Response to Parathyroid Hormone Stimulation.

L. Qin, J. Tamasi, L. Raggatt, X. Li, J. H. M. Feyen, D. C. Lee, E. DiCicco-Bloom, and N. C. Partridge (2005)
J. Biol. Chem. 280, 3974-3981
 |  Abstract »  |  Full Text »  |  PDF »

Parathyroid Hormone Secretion and Action: Evidence for Discrete Receptors for the Carboxyl-Terminal Region and Related Biological Actions of Carboxyl- Terminal Ligands.

T. M. Murray, L. G. Rao, P. Divieti, and F. R. Bringhurst (2005)
Endocr. Rev. 26, 78-113
 |  Abstract »  |  Full Text »  |  PDF »

Stimulation of Cortisol Release by the N Terminus of Teleost Parathyroid Hormone-Related Protein in Interrenal Cells in Vitro.

J. Rotllant, P. M. Guerreiro, L. Anjos, B. Redruello, A. V. M. Canario, and D. M. Power (2005)
Endocrinology 146, 71-76
 |  Abstract »  |  Full Text »  |  PDF »

Stimulatory G protein directly regulates hypertrophic differentiation of growth plate cartilage in vivo.

M. Bastepe, L. S. Weinstein, N. Ogata, H. Kawaguchi, H. Juppner, H. M. Kronenberg, and U.-i. Chung (2004)
PNAS 101, 14794-14799
 |  Abstract »  |  Full Text »  |  PDF »

Intravenous Delivery of PTH/PTHrP Type 1 Receptor cDNA to Rats Decreases Heart Rate, Blood Pressure, Renal Tone, Renin Angiotensin System, and Stress-Induced Cardiovascular Responses.

S. Fritsch, V. Lindner, S. Welsch, T. Massfelder, M. Grima, S. Rothhut, M. Barthelmebs, and J.-J. Helwig (2004)
J. Am. Soc. Nephrol. 15, 2588-2600
 |  Abstract »  |  Full Text »  |  PDF »

Parathyroid Hormone-Related Peptide Is Required for Increased Trabecular Bone Volume in Parathyroid Hormone-Null Mice.

D. Miao, J. Li, Y. Xue, H. Su, A. C. Karaplis, and D. Goltzman (2004)
Endocrinology 145, 3554-3562
 |  Abstract »  |  Full Text »  |  PDF »

Impact of the Mitogen-activated Protein Kinase Pathway on Parathyroid Hormone-related Protein Actions in Osteoblasts.

C. Chen, A. J. Koh, N. S. Datta, J. Zhang, E. T. Keller, G. Xiao, R. T. Franceschi, N. J. D'Silva, and L. K. McCauley (2004)
J. Biol. Chem. 279, 29121-29129
 |  Abstract »  |  Full Text »  |  PDF »

Parathyroid responsiveness to hypocalcemic and hypercalcemic stimuli in adult growth hormone deficiency after growth hormone replacement.

A. M. Ahmad, M. T. Hopkins, J. Thomas, B. H. Durham, W. D. Fraser, and J. P. Vora (2004)
Am J Physiol Endocrinol Metab 286, E986-E993
 |  Abstract »  |  Full Text »  |  PDF »

Skeletal Abnormalities in Pth-Null Mice Are Influenced by Dietary Calcium.

D. Miao, B. He, B. Lanske, X.-Y. Bai, X.-K. Tong, G. N. Hendy, D. Goltzman, and A. C. Karaplis (2004)
Endocrinology 145, 2046-2053
 |  Abstract »  |  Full Text »  |  PDF »

Systemic and Local Regulation of the Growth Plate.

B. C. J. van der Eerden, M. Karperien, and J. M. Wit (2003)
Endocr. Rev. 24, 782-801
 |  Abstract »  |  Full Text »  |  PDF »

Familial Hypocalciuric Hypercalcemia in a Woman with Metastatic Breast Cancer: A Case Report of Mistaken Identity.

C. Marcocci, S. Borsari, E. Pardi, G. Dipollina, T. Giacomelli, A. Pinchera, and F. Cetani (2003)
J. Clin. Endocrinol. Metab. 88, 5132-5136
 |  Abstract »  |  Full Text »  |  PDF »

Parathyroid Hormone-Related Protein Induces Insulin Expression Through Activation of MAP Kinase-Specific Phosphatase-1 That Dephosphorylates c-Jun NH2-Terminal Kinase in Pancreatic {beta}-Cells.

B. Zhang, M. Hosaka, Y. Sawada, S. Torii, S. Mizutani, M. Ogata, T. Izumi, and T. Takeuchi (2003)
Diabetes 52, 2720-2730
 |  Abstract »  |  Full Text »  |  PDF »

Parathyroid Hormone-induced E4BP4/NFIL3 Down-regulates Transcription in Osteoblasts.

I. C. Ozkurt and S. Tetradis (2003)
J. Biol. Chem. 278, 26803-26809
 |  Abstract »  |  Full Text »  |  PDF »

Centrally Administered Tuberoinfundibular Peptide of 39 Residues Inhibits Arginine Vasopressin Release in Conscious Rats.

Y. Sugimura, T. Murase, S. Ishizaki, K. Tachikawa, H. Arima, Y. Miura, T. B. Usdin, and Y. Oiso (2003)
Endocrinology 144, 2791-2796
 |  Abstract »  |  Full Text »  |  PDF »

Gene Expression Profiles and Transcription Factors Involved in Parathyroid Hormone Signaling in Osteoblasts Revealed by Microarray and Bioinformatics.

L. Qin, P. Qiu, L. Wang, X. Li, J. T. Swarthout, P. Soteropoulos, P. Tolias, and N. C. Partridge (2003)
J. Biol. Chem. 278, 19723-19731
 |  Abstract »  |  Full Text »  |  PDF »

Parathyroid Hormone Enhances Mechanically Induced Bone Formation, Possibly Involving L-Type Voltage-Sensitive Calcium Channels.

J. Li, R. L. Duncan, D. B. Burr, V. H. Gattone, and C. H. Turner (2003)
Endocrinology 144, 1226-1233
 |  Abstract »  |  Full Text »  |  PDF »

PTHrP regulates cerebral blood flow and is neuroprotective.

C. M. Macica and A. E. Broadus (2003)
Am J Physiol Regulatory Integrative Comp Physiol 284, R1019-R1020
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Parathyroid Hormone Regulation of Type II Sodium-Phosphate Cotransporters Is Dependent on an A Kinase Anchoring Protein.

S. J. Khundmiri, M. J. Rane, and E. D. Lederer (2003)
J. Biol. Chem. 278, 10134-10141
 |  Abstract »  |  Full Text »  |  PDF »

Androgen Regulation of Parathyroid Hormone-Related Peptide Production in Human Prostate Cancer Cells.

H. Pizzi, J. Gladu, L. Carpio, D. Miao, D. Goltzman, and S. A. Rabbani (2003)
Endocrinology 144, 858-867
 |  Abstract »  |  Full Text »  |  PDF »

Dual Regulation of the Parathyroid Hormone (PTH)/PTH-Related Peptide Receptor Signaling by Protein Kinase C and {beta}-Arrestins.

M. Castro, F. Dicker, J.-P. Vilardaga, C. Krasel, M. Bernhardt, and M. J. Lohse (2002)
Endocrinology 143, 3854-3865
 |  Abstract »  |  Full Text »  |  PDF »

Coexpression of Parathyroid Hormone Related Protein and Its Receptor in Early Breast Cancer Predicts Poor Patient Survival.

R. Linforth, N. Anderson, R. Hoey, T. Nolan, S. Downey, G. Brady, L. Ashcroft, and N. Bundred (2002)
Clin. Cancer Res. 8, 3172-3177
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for a Regulatory Role of Inducible cAMP Early Repressor in Protein Kinase A-Mediated Enhancement of Vitamin D Receptor Expression and Modulation of Hormone Action.

M. Huening, G. Yehia, C. A. Molina, and S. Christakos (2002)
Mol. Endocrinol. 16, 2052-2064
 |  Abstract »  |  Full Text »  |  PDF »

Purification and Characterization of a Receptor for Human Parathyroid Hormone and Parathyroid Hormone-related Peptide.

M. Shimada, X. Chen, T. Cvrk, H. Hilfiker, M. Parfenova, and G. V. Segre (2002)
J. Biol. Chem. 277, 31774-31780
 |  Abstract »  |  Full Text »  |  PDF »

New Signaling Pathway for Parathyroid Hormone and Cyclic AMP Action on Extracellular-regulated Kinase and Cell Proliferation in Bone Cells. CHECKPOINT OF MODULATION BY CYCLIC AMP.

T. Fujita, T. Meguro, R. Fukuyama, H. Nakamuta, and M. Koida (2002)
J. Biol. Chem. 277, 22191-22200
 |  Abstract »  |  Full Text »  |  PDF »

Parathyroid Hormone and Parathyroid Hormone-related Protein Exert Both Pro- and Anti-apoptotic Effects in Mesenchymal Cells.

H.-L. Chen, B. Demiralp, A. Schneider, A. J. Koh, C. Silve, C.-Y. Wang, and L. K. McCauley (2002)
J. Biol. Chem. 277, 19374-19381
 |  Abstract »  |  Full Text »  |  PDF »

Association between AAAG Repeat Polymorphism in the P3 Promoter of the Human Parathyroid Hormone (PTH)/PTH-Related Peptide Receptor Gene and Adult Height, Urinary Pyridinoline Excretion, and Promoter Activity.

M. Minagawa, T. Yasuda, T. Watanabe, K. Minamitani, Y. Takahashi, D. Goltzman, J. H. White, G. N. Hendy, and Y. Kohno (2002)
J. Clin. Endocrinol. Metab. 87, 1791-1796
 |  Abstract »  |  Full Text »  |  PDF »

Type 1 Parathyroid Hormone Receptor Expression Level Modulates Renal Tone and Plasma Renin Activity in Spontaneously Hypertensive Rat.

T. Massfelder, N. Taesch, S. Fritsch, A. Eichinger, M. Barthelmebs, A. F. Stewart, and J.-J. Helwig (2002)
J. Am. Soc. Nephrol. 13, 639-648
 |  Abstract »  |  Full Text »  |  PDF »

Internalization Determinants of the Parathyroid Hormone Receptor Differentially Regulate beta -Arrestin/Receptor Association.

J.-P. Vilardaga, C. Krasel, S. Chauvin, T. Bambino, M. J. Lohse, and R. A. Nissenson (2002)
J. Biol. Chem. 277, 8121-8129
 |  Abstract »  |  Full Text »  |  PDF »

PTH and DA regulate Na-K ATPase through divergent pathways.

S. J. Khundmiri and E. Lederer (2002)
Am J Physiol Renal Physiol 282, F512-F522
 |  Abstract »  |  Full Text »  |  PDF »

Intracrine PTHrP Protects against Serum Starvation-Induced Apoptosis and Regulates the Cell Cycle in MCF-7 Breast Cancer Cells.

V. A. Tovar Sepulveda, X. Shen, and M. Falzon (2002)
Endocrinology 143, 596-606
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of the Receptor for PTH and PTHrP Is Required for Internalization and Regulates Receptor Signaling.

H. A. W. Tawfeek, F. Qian, and A. B. Abou-Samra (2002)
Mol. Endocrinol. 16, 1-13
 |  Abstract »  |  Full Text »  |  PDF »

Regions in Rat and Human Parathyroid Hormone (PTH) 2 Receptors Controlling Receptor Interaction with PTH and with Antagonist Ligands.

C. P. Goold, T. B. Usdin, and S. R. J. Hoare (2001)
J. Pharmacol. Exp. Ther. 299, 678-690
 |  Abstract »  |  Full Text »  |  PDF »

OPG and PTH-(1-34) Have Additive Effects on Bone Density and Mechanical Strength in Osteopenic Ovariectomized Rats.

P. J. Kostenuik, C. Capparelli, S. Morony, S. Adamu, G. Shimamoto, V. Shen, D. L. Lacey, and C. R. Dunstan (2001)
Endocrinology 142, 4295-4304
 |  Abstract »  |  Full Text »  |  PDF »

Matrix {gamma}-Carboxyglutamic Acid Protein Is a Key Regulator of PTH-Mediated Inhibition of Mineralization in MC3T3-E1 Osteoblast-Like Cells.

R. Gopalakrishnan, H. Ouyang, M. J. Somerman, L. K. McCauley, and R. T. Franceschi (2001)
Endocrinology 142, 4379-4388
 |  Abstract »  |  Full Text »  |  PDF »

Functional Segregation of the Highly Conserved Basic Motifs within the Third Endoloop of the Human Secretin Receptor.

K. Y.-Y. Chan, R. T.-K. Pang, and B. K.-C. Chow (2001)
Endocrinology 142, 3926-3934
 |  Abstract »  |  Full Text »  |  PDF »

Induction of osteoblast differentiation indexes by PTHrP in MG-63 cells involves multiple signaling pathways.

L. Carpio, J. Gladu, D. Goltzman, and S. A. Rabbani (2001)
Am J Physiol Endocrinol Metab 281, E489-E499
 |  Abstract »  |  Full Text »  |  PDF »

Parathyroid hormone receptor internalization is independent of protein kinase A and phospholipase C activation.

H. A. W. Tawfeek, J. Che, F. Qian, and A. B. Abou-Samra (2001)
Am J Physiol Endocrinol Metab 281, E545-E557
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of Parathyroid Hormone (PTH)/Secretin Receptor Chimeras Differentiates the Role of Functional Domains in the PTH/ PTH-Related Peptide (PTHrP) Receptor on Hormone Binding and Receptor Activation.

J.-P. Vilardaga, I. Lin, and R. A. Nissenson (2001)
Mol. Endocrinol. 15, 1186-1199
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Cloning of Ovine and Bovine Growth Hormone-Releasing Hormone Receptors: The Ovine Receptor Is C-Terminally Truncated.

R. Horikawa, B. D. Gaylinn, C. E. Lyons Jr., and M. O. Thorner (2001)
Endocrinology 142, 2660-2668
 |  Abstract »  |  Full Text »  |  PDF »

Absence of Functional Type 1 Parathyroid Hormone (PTH)/PTH-Related Protein Receptors in Humans Is Associated with Abnormal Breast Development and Tooth Impaction.

J. J. Wysolmerski, S. Cormier, W. M. Philbrick, P. Dann, J.-P. Zhang, J. Roume, A.-L. Delezoide, and C. Silve (2001)
J. Clin. Endocrinol. Metab. 86, 1788-1794
 |  Abstract »  |  Full Text »

Analysis of the P3 Promoter of the Human Parathyroid Hormone (PTH)/PTH-Related Peptide Receptor Gene in Pseudohypoparathyroidism Type 1b.

M. Minagawa, T. Watanabe, Y. Kohno, H. Mochizuki, G. N. Hendy, D. Goltzman, J. H. White, and T. Yasuda (2001)
J. Clin. Endocrinol. Metab. 86, 1394-1397
 |  Abstract »  |  Full Text »

Paradoxical actions of exogenous and endogenous parathyroid hormone-related protein on renal vascular smooth muscle cell proliferation: reversion in the SHR model of genetic hypertension.

T. MASSFELDER, N. TAESCH, N. ENDLICH, A. EICHINGER, B. ESCANDE, K. ENDLICH, M. BARTHELMEBS, and J.-J. HELWIG (2001)
FASEB J 15, 707-718
 |  Abstract »  |  Full Text »  |  PDF »

Parathyroid Hormone Induces Expression of the Nuclear Orphan Receptor Nurr1 in Bone Cells.

S. Tetradis, O. Bezouglaia, and A. Tsingotjidou (2001)
Endocrinology 142, 663-670
 |  Abstract »  |  Full Text »  |  PDF »

Receptors for the Carboxyl-Terminal Region of PTH(1-84) Are Highly Expressed in Osteocytic Cells.

P. Divieti, N. Inomata, K. Chapin, R. Singh, H. Juppner, and F. R. Bringhurst (2001)
Endocrinology 142, 916-925
 |  Abstract »  |  Full Text »  |  PDF »

Parathyroid hormone-related protein maintains mammary epithelial fate and triggers nipple skin differentiation during embryonic breast development.

J Foley, P Dann, J Hong, J Cosgrove, B Dreyer, D Rimm, M Dunbar, W Philbrick, and J Wysolmerski (2001)
Development 128, 513-525
 |  Abstract »  |  PDF »

ADAMTS-1: A Cellular Disintegrin and Metalloprotease with Thrombospondin Motifs Is a Target for Parathyroid Hormone in Bone.

R. R. Miles, J. P. Sluka, D. L. Halladay, R. F. Santerre, L. V. Hale, L. Bloem, K. Thirunavukkarasu, R. J. S. Galvin, J. M. Hock, and J. E. Onyia (2000)
Endocrinology 141, 4533-4542
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Obligate Mitogen-Activated Protein Kinase Activation in Parathyroid Hormone Stimulation of Calcium Transport But Not Calcium Signaling.

W. B. Sneddon, F. Liu, F. A. Gesek, and P. A. Friedman (2000)
Endocrinology 141, 4185-4193
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Structural Insights into the Amino-Terminus of the Secretin Receptor: I. Status of Cysteine and Cystine Residues.

Y. W. Asmann, M. Dong, S. Ganguli, E. M. Hadac, and L. J. Miller (2000)
Mol. Pharmacol. 58, 911-919
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Positive and Negative Control of the Expression of Parathyroid Hormone (PTH)/PTH-Related Protein Receptor Via Proximal Promoter P3 in Human Osteoblast-Like Cells.

D. Manen, G. Palmer, J.-P. Bonjour, and R. Rizzoli (2000)
J. Clin. Endocrinol. Metab. 85, 3376-3382
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Evaluating the Ligand Specificity of Zebrafish Parathyroid Hormone (PTH) Receptors: Comparison of PTH, PTH-Related Protein, and Tuberoinfundibular Peptide of 39 Residues.

S. R. J. Hoare, D. A. Rubin, H. Juppner, and T. B. Usdin (2000)
Endocrinology 141, 3080-3086
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Functional parathyroid hormone receptors are present in an umbilical vein endothelial cell line.

C. M. Isales, B. Sumpio, R. J. Bollag, Q. Zhong, K.-H. Ding, W. Du, J. Rodriguez-Commes, R. Lopez, O. R. Rosales, J. Gasalla-Herraiz, et al. (2000)
Am J Physiol Endocrinol Metab 279, E654-E662
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Dissection of Differentially Regulated (G+C)-Rich Promoters of the Human Parathyroid Hormone (PTH)/PTH-Related Peptide Receptor Gene.

M. Minagawa, M. Y. Kwan, J. D. Bettoun, F. W. Mansour, J. Dassa, G. N. Hendy, D. Goltzman, and J. H. White (2000)
Endocrinology 141, 2410-2421
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Phosphorylation of SOX9 by Cyclic AMP-Dependent Protein Kinase A Enhances SOX9's Ability To Transactivate a Col2a1 Chondrocyte-Specific Enhancer.

W. Huang, X. Zhou, V. Lefebvre, and B. de Crombrugghe (2000)
Mol. Cell. Biol. 20, 4149-4158
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Enhanced Growth of MCF-7 Breast Cancer Cells Overexpressing Parathyroid Hormone-Related Peptide.

M. Falzon and P. Du (2000)
Endocrinology 141, 1882-1892
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Luminal and contraluminal action of 1-34 and 3-34 PTH peptides on renal type IIa Na-Pi cotransporter.

M. Traebert, H. Volkl, J. Biber, H. Murer, and B. Kaissling (2000)
Am J Physiol Renal Physiol 278, F792-F798
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Parathyroid Hormone Regulation of the Rat Collagenase-3 Promoter by Protein Kinase A-dependent Transactivation of Core Binding Factor alpha 1.

N. Selvamurugan, M. R. Pulumati, D. R. Tyson, and N. C. Partridge (2000)
J. Biol. Chem. 275, 5037-5042
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Apoptosis Mediated by Activation of the G Protein-Coupled Receptor for Parathyroid Hormone (PTH)/ PTH-Related Protein (PTHrP).

P. R. Turner, S. Mefford, S. Christakos, and R. A. Nissenson (2000)
Mol. Endocrinol. 14, 241-254
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Parathyroid Hormone Stimulates Extracellular Signal-Regulated Kinase (ERK) Activity Through Two Independent Signal Transduction Pathways: Roleof ERK in Sodium-Phosphate Cotransport.

E. D. LEDERER, S. S. SOHI, and K. R. MCLEISH (2000)
J. Am. Soc. Nephrol. 11, 222-231
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Parathyroid Hormone Controls the Size of the Intracellular Ca2+ Stores Available to Receptors Linked to Inositol Trisphosphate Formation.

A. D. Short and C. W. Taylor (2000)
J. Biol. Chem. 275, 1807-1813
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Activation of Osteocalcin Transcription Involves Interaction of Protein Kinase A- and Protein Kinase C-dependent Pathways.

G. Boguslawski, L. V. Hale, X.-P. Yu, R. R. Miles, J. E. Onyia, R. F. Santerre, and S. Chandrasekhar (2000)
J. Biol. Chem. 275, 999-1006
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Dynamic Regulation of RGS2 in Bone: Potential New Insights into Parathyroid Hormone Signaling Mechanisms.

R. R. Miles, J. P. Sluka, R. F. Santerre, L. V. Hale, L. Bloem, G. Boguslawski, K. Thirunavukkarasu, J. M. Hock, and J. E. Onyia (2000)
Endocrinology 141, 28-36
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The Glucagon-Like Peptides.

T. J. Kieffer and J. Francis Habener (1999)
Endocr. Rev. 20, 876-913
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PTH and PTHrP: Similar Structures but Different Functions.

K.-D. Schluter (1999)
Physiology 14, 243-249
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Parathyroid Hormone-related Protein as a Growth Regulator of Prostate Carcinoma.

K. M. Dougherty, E. A. G. Blomme, A. J. Koh, J. E. Henderson, K. J. Pienta, T. J. Rosol, and L. K. McCauley (1999)
Cancer Res. 59, 6015-6022
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The genetic transformation of bone biology.

G. Karsenty (1999)
Genes & Dev. 13, 3037-3051
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The Hydrophobic Residues Phenylalanine 184 and Leucine 187 in the Type-1 Parathyroid Hormone (PTH) Receptor Functionally Interact with the Amino-terminal Portion of PTH-(1-34).

P. H. Carter, M. Shimizu, M. D. Luck, and T. J. Gardella (1999)
J. Biol. Chem. 274, 31955-31960
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Studies of the N-Terminal Region of a Parathyroid Hormone-Related Peptide(1-36) Analog: Receptor Subtype-Selective Agonists, Antagonists, and Photochemical Cross-Linking Agents.

P. H. Carter, H. Jüppner, and T. J. Gardella (1999)
Endocrinology 140, 4972-4981
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Physiological Regulation of G Protein-Linked Signaling.

A. J. Morris and C. C. Malbon (1999)
Physiol Rev 79, 1373-1430
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