Science 15 November 1991: Vol. 254. no. 5034, pp. 1001 - 1003 DOI: 10.1126/science.1948068

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Articles

Structure-Function Relationships in Miscoding by Sulfolobus solfataricus DNA Polymerase Dpo4: GUANINE N2,N2-DIMETHYL SUBSTITUTION PRODUCES INACTIVE AND MISCODING POLYMERASE COMPLEXES.

H. Zhang, R. L. Eoff, I. D. Kozekov, C. J. Rizzo, M. Egli, and F. P. Guengerich (2009)
J. Biol. Chem. 284, 17687-17699
 |  Abstract »  |  Full Text »  |  PDF »

Oxidative stress-related genotypes, fruit and vegetable consumption and breast cancer risk.

Y. Li, C. B. Ambrosone, M. J. McCullough, J. Ahn, V. L. Stevens, M. J. Thun, and C.-C. Hong (2009)
Carcinogenesis 30, 777-784
 |  Abstract »  |  Full Text »  |  PDF »

Wnt/{beta}-Catenin Signaling Regulates Cytokine-Induced Human Inducible Nitric Oxide Synthase Expression by Inhibiting Nuclear Factor-{kappa}B Activation in Cancer Cells.

Q. Du, X. Zhang, J. Cardinal, Z. Cao, Z. Guo, L. Shao, and D. A. Geller (2009)
Cancer Res. 69, 3764-3771
 |  Abstract »  |  Full Text »  |  PDF »

Important role of the nucleotide excision repair pathway in Mycobacterium smegmatis in conferring protection against commonly encountered DNA-damaging agents.

K. Kurthkoti, P. Kumar, R. Jain, and U. Varshney (2008)
Microbiology 154, 2776-2785
 |  Abstract »  |  Full Text »  |  PDF »

A Nitric Oxide-Inducible Lactate Dehydrogenase Enables Staphylococcus aureus to Resist Innate Immunity.

A. R. Richardson, S. J. Libby, and F. C. Fang (2008)
Science 319, 1672-1676
 |  Abstract »  |  Full Text »  |  PDF »

Fat transforms ascorbic acid from inhibiting to promoting acid-catalysed N-nitrosation.

E Combet, S Paterson, K Iijima, J Winter, W Mullen, A Crozier, T Preston, and K E L McColl (2007)
Gut 56, 1678-1684
 |  Abstract »  |  Full Text »  |  PDF »

Relationships between polymorphisms in NOS3 and MPO genes, cigarette smoking and risk of post-menopausal breast cancer.

J. Yang, C. B. Ambrosone, C.-C. Hong, J. Ahn, C. Rodriguez, M. J. Thun, and E. E. Calle (2007)
Carcinogenesis 28, 1247-1253
 |  Abstract »  |  Full Text »  |  PDF »

Lack of iNOS Facilitates MCMV Spread in the Retina.

M. Zhang, J. Zhou, B. Marshall, H. Xin, and S. S. Atherton (2007)
Invest. Ophthalmol. Vis. Sci. 48, 285-292
 |  Abstract »  |  Full Text »  |  PDF »

Nitric Oxide and Peroxynitrite in Health and Disease.

P. Pacher, J. S. Beckman, and L. Liaudet (2007)
Physiol Rev 87, 315-424
 |  Abstract »  |  Full Text »  |  PDF »

Mutagenesis induced by the nitric oxide donor sodium nitroprusside in mouse cells.

D.-H. Lee and G. P. Pfeifer (2007)
Mutagenesis 22, 63-67
 |  Abstract »  |  Full Text »  |  PDF »

Nitric Oxide Exposure Diverts Neural Stem Cell Fate from Neurogenesis Towards Astrogliogenesis.

R. Covacu, A. I. Danilov, B. S. Rasmussen, K. Hallen, M. C. Moe, A. Lobell, C. B. Johansson, M. A. Svensson, T. Olsson, and L. Brundin (2006)
Stem Cells 24, 2792-2800
 |  Abstract »  |  Full Text »  |  PDF »

MDM2 Promoter Polymorphism Is Associated With Both an Increased Susceptibility to Gastric Carcinoma and Poor Prognosis.

N. Ohmiya, A. Taguchi, N. Mabuchi, A. Itoh, Y. Hirooka, Y. Niwa, and H. Goto (2006)
J. Clin. Oncol. 24, 4434-4440
 |  Abstract »  |  Full Text »  |  PDF »

Tuberculosis Chemotherapy: the Influence of Bacillary Stress and Damage Response Pathways on Drug Efficacy.

D. F. Warner and V. Mizrahi (2006)
Clin. Microbiol. Rev. 19, 558-570
 |  Abstract »  |  Full Text »  |  PDF »

Up-regulation of Microglial CD11b Expression by Nitric Oxide.

A. Roy, Y. K. Fung, X. Liu, and K. Pahan (2006)
J. Biol. Chem. 281, 14971-14980
 |  Abstract »  |  Full Text »  |  PDF »

Mutagenic Actions of Nitrogen Oxides.

K. Kilinc and A. Kilinc (2005)
Indoor and Built Environment 14, 503-512
 |  Abstract »  |  PDF »

Interleukin-8 Promoter Polymorphism Increases the Risk of Atrophic Gastritis and Gastric Cancer in Japan.

A. Taguchi, N. Ohmiya, K. Shirai, N. Mabuchi, A. Itoh, Y. Hirooka, Y. Niwa, and H. Goto (2005)
Cancer Epidemiol. Biomarkers Prev. 14, 2487-2493
 |  Abstract »  |  Full Text »  |  PDF »

Cytokines Induce Nitric Oxide-mediated mtDNA Damage and Apoptosis in Oligodendrocytes: PROTECTIVE ROLE OF TARGETING 8-OXOGUANINE GLYCOSYLASE TO MITOCHONDRIA.

N. M. Druzhyna, S. I. Musiyenko, G. L. Wilson, and S. P. LeDoux (2005)
J. Biol. Chem. 280, 21673-21679
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of Prostaglandin Biosynthesis by Nitric Oxide and Nitric Oxide Donors.

V. Mollace, C. Muscoli, E. Masini, S. Cuzzocrea, and D. Salvemini (2005)
Pharmacol. Rev. 57, 217-252
 |  Abstract »  |  Full Text »  |  PDF »

Assessment of the genotoxic potential of nitric oxide-induced guanine lesions by in vitro reactions with Escherichia coli DNA polymerase I.

T. Nakano, K. Asagoshi, H. Terato, T. Suzuki, and H. Ide (2005)
Mutagenesis 20, 209-216
 |  Abstract »  |  Full Text »  |  PDF »

Repair activity of base and nucleotide excision repair enzymes for guanine lesions induced by nitrosative stress.

T. Nakano, A. Katafuchi, R. Shimizu, H. Terato, T. Suzuki, H. Tauchi, K. Makino, M. Skorvaga, B. Van Houten, and H. Ide (2005)
Nucleic Acids Res. 33, 2181-2191
 |  Abstract »  |  Full Text »  |  PDF »

The Moving Frontier in Nitric Oxide-Dependent Signaling.

C. Nathan (2004)
Sci. STKE 2004, pe52
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of Resistance to Oxidative and Nitrosative Stress: Implications for Fungal Survival in Mammalian Hosts.

T. A. Missall, J. K. Lodge, and J. E. McEwen (2004)
Eukaryot. Cell 3, 835-846
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Nitric Oxide in Health and Disease of the Respiratory System.

F. L. M. Ricciardolo, P. J. Sterk, B. Gaston, and G. Folkerts (2004)
Physiol Rev 84, 731-765
 |  Abstract »  |  Full Text »  |  PDF »

Mechanism and importance of post-translational regulation of nitrate reductase.

C. Lillo, C. Meyer, U. S. Lea, F. Provan, and S. Oltedal (2004)
J. Exp. Bot. 55, 1275-1282
 |  Abstract »  |  Full Text »  |  PDF »

Role of nitric oxide modified DNA in the etiopathogenesis of systemic lupus erythematosus.

K Dixit and R Ali (2004)
Lupus 13, 95-100
 |  Abstract »  |  PDF »

Theiler's Virus Infection: a Model for Multiple Sclerosis.

E. L. Oleszak, J. R. Chang, H. Friedman, C. D. Katsetos, and C. D. Platsoucas (2004)
Clin. Microbiol. Rev. 17, 174-207
 |  Abstract »  |  Full Text »  |  PDF »

Oxidant metabolism in chronic obstructive pulmonary disease.

A.W. Boots, G.R.M.M. Haenen, and A. Bast (2003)
Eur. Respir. J. 22, 14s-27s
 |  Abstract »  |  Full Text »  |  PDF »

Genetic requirements for mycobacterial survival during infection.

C. M. Sassetti and E. J. Rubin (2003)
PNAS 100, 12989-12994
 |  Abstract »  |  Full Text »  |  PDF »

Macrophage Endothelial Nitric-oxide Synthase Autoregulates Cellular Activation and Pro-inflammatory Protein Expression.

L. Connelly, A. T. Jacobs, M. Palacios-Callender, S. Moncada, and A. J. Hobbs (2003)
J. Biol. Chem. 278, 26480-26487
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of bacterial DNA replication by zinc mobilization during nitrosative stress.

J. M. Schapiro, S. J. Libby, and F. C. Fang (2003)
PNAS 100, 8496-8501
 |  Abstract »  |  Full Text »  |  PDF »

Importance of Uracil DNA Glycosylase in Pseudomonas aeruginosa and Mycobacterium smegmatis, G+C-rich Bacteria, in Mutation Prevention, Tolerance to Acidified Nitrite, and Endurance in Mouse Macrophages.

J. Venkatesh, P. Kumar, P. S. M. Krishna, R. Manjunath, and U. Varshney (2003)
J. Biol. Chem. 278, 24350-24358
 |  Abstract »  |  Full Text »  |  PDF »

DNA-Protein Cross-link Formation Mediated by Oxanine: A NOVEL GENOTOXIC MECHANISM OF NITRIC OXIDE-INDUCED DNA DAMAGE.

T. Nakano, H. Terato, K. Asagoshi, A. Masaoka, M. Mukuta, Y. Ohyama, T. Suzuki, K. Makino, and H. Ide (2003)
J. Biol. Chem. 278, 25264-25272
 |  Abstract »  |  Full Text »  |  PDF »

Suppressed catalytic activity of base excision repair enzymes on rotationally positioned uracil in nucleosomes.

B. C. Beard, S. H. Wilson, and M. J. Smerdon (2003)
PNAS 100, 7465-7470
 |  Abstract »  |  Full Text »  |  PDF »

A Diarylheptanoid from Lesser Galangal (Alpinia officinarum) Inhibits Proinflammatory Mediators via Inhibition of Mitogen-Activated Protein Kinase, p44/42, and Transcription Factor Nuclear Factor-{kappa}B.

P. N. Yadav, Z. Liu, and M. M. Rafi (2003)
J. Pharmacol. Exp. Ther. 305, 925-931
 |  Abstract »  |  Full Text »  |  PDF »

Vitamin C as an Antioxidant: Evaluation of Its Role in Disease Prevention.

S. J. Padayatty, A. Katz, Y. Wang, P. Eck, O. Kwon, J.-H. Lee, S. Chen, C. Corpe, A. Dutta, S. K Dutta, et al. (2003)
J. Am. Coll. Nutr. 22, 18-35
 |  Abstract »  |  Full Text »  |  PDF »

Multiple roles of nitric oxide in the airways.

F L M Ricciardolo (2003)
Thorax 58, 175-182
 |  Abstract »  |  Full Text »  |  PDF »

Gemfibrozil, a Lipid-lowering Drug, Inhibits the Induction of Nitric-oxide Synthase in Human Astrocytes.

K. Pahan, M. Jana, X. Liu, B. S. Taylor, C. Wood, and S. M. Fischer (2002)
J. Biol. Chem. 277, 45984-45991
 |  Abstract »  |  Full Text »  |  PDF »

Novel repair activities of AlkA (3-methyladenine DNA glycosylase II) and endonuclease VIII for xanthine and oxanine, guanine lesions induced by nitric oxide and nitrous acid.

H. Terato, A. Masaoka, K. Asagoshi, A. Honsho, Y. Ohyama, T. Suzuki, M. Yamada, K. Makino, K. Yamamoto, and H. Ide (2002)
Nucleic Acids Res. 30, 4975-4984
 |  Abstract »  |  Full Text »  |  PDF »

Hypermutable Bases in the p53 Cancer Gene Are at Vulnerable Positions in DNA Secondary Structures.

B. E. Wright, J. M. Reimers, K. H. Schmidt, and D. K. Reschke (2002)
Cancer Res. 62, 5641-5644
 |  Abstract »  |  Full Text »  |  PDF »

Regional analysis of p53 mutations in rheumatoid arthritis synovium.

Y. Yamanishi, D. L. Boyle, S. Rosengren, D. R. Green, N. J. Zvaifler, and G. S. Firestein (2002)
PNAS 99, 10025-10030
 |  Abstract »  |  Full Text »  |  PDF »

Reactive Nitrogen Intermediates in Giant Cell Arteritis : Selective Nitration of Neocapillaries.

A. Borkowski, B. R. Younge, L. Szweda, B. Mock, J. Bjornsson, K. Moeller, J. J. Goronzy, and C. M. Weyand (2002)
Am. J. Pathol. 161, 115-123
 |  Abstract »  |  Full Text »  |  PDF »

Carnosol, an antioxidant in rosemary, suppresses inducible nitric oxide synthase through down-regulating nuclear factor-{kappa}B in mouse macrophages.

A.-H. Lo, Y.-C. Liang, S.-Y. Lin-Shiau, C.-T. Ho, and J.-K. Lin (2002)
Carcinogenesis 23, 983-991
 |  Abstract »  |  Full Text »  |  PDF »

Red Wine and Black Tea Polyphenols Modulate the Expression of Cycloxygenase-2, Inducible Nitric Oxide Synthase and Glutathione-Related Enzymes in Azoxymethane-Induced F344 Rat Colon Tumors.

C. Luceri, G. Caderni, A. Sanna, and P. Dolara (2002)
J. Nutr. 132, 1376-1379
 |  Abstract »  |  Full Text »  |  PDF »

Helicobacter pylori arginase inhibits nitric oxide production by eukaryotic cells: A strategy for bacterial survival.

A. P. Gobert, D. J. McGee, M. Akhtar, G. L. Mendz, J. C. Newton, Y. Cheng, H. L. T. Mobley, and K. T. Wilson (2001)
PNAS 98, 13844-13849
 |  Abstract »  |  Full Text »  |  PDF »

Oxidative Stress and p53 Mutations in the Carcinogenesis of Iron Overload-Associated Hepatocellular Carcinoma.

A. J. Marrogi, M. A. Khan, H. E. van Gijssel, J. A. Welsh, H. Rahim, A. J. Demetris, K. V. Kowdley, S. P. Hussain, J. Nair, H. Bartsch, et al. (2001)
J Natl Cancer Inst 93, 1652-1655
 |  Full Text »  |  PDF »

Chronic long-term nitrate therapy: possible cytogenetic effect in humans?.

M. G. Andreassi, E. Picano, S. Del Ry, N. Botto, M. G. Colombo, D. Giannessi, V. Lubrano, C. Vassalle, and A. Biagini (2001)
Mutagenesis 16, 517-521
 |  Abstract »  |  Full Text »  |  PDF »

Oxidative and nitrosative stress in acute renal ischemia.

E. Noiri, A. Nakao, K. Uchida, H. Tsukahara, M. Ohno, T. Fujita, S. Brodsky, and M. S. Goligorsky (2001)
Am J Physiol Renal Physiol 281, F948-F957
 |  Abstract »  |  Full Text »  |  PDF »

Nitric oxide in gastrointestinal epithelial cell carcinogenesis: linking inflammation to oncogenesis.

M. Jaiswal, N. F. LaRusso, and G. J. Gores (2001)
Am J Physiol Gastrointest Liver Physiol 281, G626-G634
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Listeria monocytogenes In Vivo-Induced Genes by Fluorescence-Activated Cell Sorting.

R. L. Wilson, A. R. Tvinnereim, B. D. Jones, and J. T. Harty (2001)
Infect. Immun. 69, 5016-5024
 |  Abstract »  |  Full Text »  |  PDF »

The physiological expression of inducible nitric oxide synthase (iNOS) in the human colon.

P J Roberts, G P Riley, K Morgan, R Miller, J O Hunter, and S J Middleton (2001)
J. Clin. Pathol. 54, 293-297
 |  Abstract »  |  Full Text »  |  PDF »

Biphasic Regulation of NF-{{kappa}}B Activity Underlies the Pro- and Anti-Inflammatory Actions of Nitric Oxide.

L. Connelly, M. Palacios-Callender, C. Ameixa, S. Moncada, and A. J. Hobbs (2001)
J. Immunol. 166, 3873-3881
 |  Abstract »  |  Full Text »  |  PDF »

Kinetics of formation of hypoxanthine containing base pairs by HIV-RT: RNA template effects on the base substitution frequencies.

M. R. Valentine and J. Termini (2001)
Nucleic Acids Res. 29, 1191-1199
 |  Abstract »  |  Full Text »  |  PDF »

Role of Nitric Oxide Synthase Type 2 in Acute Infection with Murine Cytomegalovirus.

S. Noda, K. Tanaka, S.-a. Sawamura, M. Sasaki, T. Matsumoto, K. Mikami, Y. Aiba, H. Hasegawa, N. Kawabe, and Y. Koga (2001)
J. Immunol. 166, 3533-3541
 |  Abstract »  |  Full Text »  |  PDF »

The Toxicology of Inhaled Nitric Oxide.

B. Weinberger, D. L. Laskin, D. E. Heck, and J. D. Laskin (2001)
Toxicol. Sci. 59, 5-16
 |  Abstract »  |  Full Text »  |  PDF »

Misincorporation of 2'-deoxyoxanosine into DNA: a molecular basis for NO-induced mutagenesis derived from theoretical calculations.

B. Hernandez, R. Soliva, F. J. Luque, and M. Orozco (2000)
Nucleic Acids Res. 28, 4873-4883
 |  Abstract »  |  Full Text »  |  PDF »

Differential effects of inhaled nitric oxide and hyperoxia on pulmonary dysfunction in newborn guinea pigs.

D. M. Gries, E. K. Tam, J. M. Blaisdell, L. M. Iwamoto, N. Fujiwara, C. F. T. Uyehara, and K. T. Nakamura (2000)
Am J Physiol Regulatory Integrative Comp Physiol 279, R1525-R1530
 |  Abstract »  |  Full Text »  |  PDF »

Inhibitory Effect of Citrus Nobiletin on Phorbol Ester-induced Skin Inflammation, Oxidative Stress, and Tumor Promotion in Mice.

A. Murakami, Y. Nakamura, K. Torikai, T. Tanaka, T. Koshiba, K. Koshimizu, S. Kuwahara, Y. Takahashi, K. Ogawa, M. Yano, et al. (2000)
Cancer Res. 60, 5059-5066
 |  Abstract »  |  Full Text »

Bax is downregulated in inflamed colonic mucosa of ulcerative colitis.

M Iimura, T Nakamura, S Shinozaki, B Iizuka, Y Inoue, S Suzuki, and N Hayashi (2000)
Gut 47, 228-235
 |  Abstract »  |  Full Text »  |  PDF »

Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens.

C. Nathan and M. U. Shiloh (2000)
PNAS 97, 8841-8848
 |  Abstract »  |  Full Text »  |  PDF »

FK409, a Spontaneous Nitric Oxide Releaser, Attenuates Allograft Vasculopathy in a Rat Aortic Transplant Model.

J. Fukada, S. Schena, I. Tack, P. Ruiz, Y. Kurimoto, M. Pang, A. Aitouche, T. Abe, L. J. Striker, and S. M. Pham (2000)
Circ. Res. 87, 66-72
 |  Abstract »  |  Full Text »  |  PDF »

Increased p53 Mutation Load in Noncancerous Colon Tissue from Ulcerative Colitis: A Cancer-prone Chronic Inflammatory Disease.

S. P. Hussain, P. Amstad, K. Raja, S. Ambs, M. Nagashima, W. P. Bennett, P. G. Shields, A.-J. Ham, J. A. Swenberg, A. J. Marrogi, et al. (2000)
Cancer Res. 60, 3333-3337
 |  Abstract »  |  Full Text »

A nitric oxide burst precedes apoptosis in angiosperm and gymnosperm callus cells and foliar tissues.

M. C. Pedroso, J.R. Magalhaes, and D. Durzan (2000)
J. Exp. Bot. 51, 1027-1036
 |  Abstract »  |  Full Text »  |  PDF »

Inhibitory Effects of Nitric Oxide and Gamma Interferon on In Vitro and In Vivo Replication of Marek's Disease Virus.

Z. Xing and K. A. Schat (2000)
J. Virol. 74, 3605-3612
 |  Abstract »  |  Full Text »

Differential Sensitivity among Nitric Oxide Donors toward ODQ-Mediated Inhibition of Vascular Relaxation.

C.-M. L. Tseng, M. A. Tabrizi-Fard, and H.-L. Fung (2000)
J. Pharmacol. Exp. Ther. 292, 737-742
 |  Abstract »  |  Full Text »

Transition mutation in codon 248 of the p53 tumor suppressor gene induced by reactive oxygen species and a nitric oxide-releasing compound.

A.-C. Souici, J. Mirkovitch, P. Hausel, L. K.Keefer, and E. Felley-Bosco (2000)
Carcinogenesis 21, 281-287
 |  Abstract »  |  Full Text »  |  PDF »

In situ detection of AP sites and DNA strand breaks bearing 3'-phosphate termini in ischemic mouse brain.

D. HUANG, A. SHENOY, J. CUI, W. HUANG, and P. K. LIU (2000)
FASEB J 14, 407-417
 |  Abstract »  |  Full Text »

Apoptosis in atherosclerosis: beneficial or detrimental?.

M. M Kockx and A. G Herman (2000)
Cardiovasc Res 45, 736-746
 |  Abstract »  |  Full Text »  |  PDF »

Nitric Oxide-Induced Increase in p21Sdi1/Cip1/Waf1 Expression During the Cell Cycle in Aortic Adventitial Fibroblasts.

M. Gu and P. Brecher (2000)
Arterioscler. Thromb. Vasc. Biol. 20, 27-34
 |  Abstract »  |  Full Text »  |  PDF »

Inflammatory Cytokines Induce DNA damage and Inhibit DNA repair in Cholangiocarcinoma Cells by a Nitric Oxide-dependent Mechanism.

M. Jaiswal, N. F. LaRusso, L. J. Burgart, and G. J. Gores (2000)
Cancer Res. 60, 184-190
 |  Abstract »  |  Full Text »

Methylation-dependent Gene Silencing Induced by Interleukin 1{beta} Via Nitric Oxide Production.

A. Hmadcha, F. J. Bedoya, F. Sobrino, and E. Pintado (1999)
J. Exp. Med. 190, 1595-1604
 |  Abstract »  |  Full Text »  |  PDF »

NOX, a novel nitric oxide scavenger, reduces bacterial translocation in rats after endotoxin challenge.

E. Dickinson, R. Tuncer, E. Nadler, P. Boyle, S. Alber, S. Watkins, and H. Ford (1999)
Am J Physiol Gastrointest Liver Physiol 277, G1281-G1287
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Chlorine Generated by the Myeloperoxidase-Hydrogen Peroxide-Chloride System of Phagocytes Produces 5-Chlorocytosine in Bacterial RNA.

J. P. Henderson, J. Byun, and J. W. Heinecke (1999)
J. Biol. Chem. 274, 33440-33448
 |  Abstract »  |  Full Text »  |  PDF »

Nitric oxide triggers programmed cell death (apoptosis) of adult rat ventricular myocytes in culture.

D. J. Pinsky, W. Aji, M. Szabolcs, E. S. Athan, Y. Liu, Y. M. Yang, R. P. Kline, K. E. Olson, and P. J. Cannon (1999)
Am J Physiol Heart Circ Physiol 277, H1189-H1199
 |  Abstract »  |  Full Text »  |  PDF »

Nitric Oxide Is an Initiator of Intercellular Signal Transduction for Stress Response after Hyperthermia in Mutant p53 Cells of Human Glioblastoma.

H. Matsumoto, S. Hayashi, M. Hatashita, K. Ohnishi, T. Ohtsubo, R. Kitai, H. Shioura, T. Ohnishi, and E. Kano (1999)
Cancer Res. 59, 3239-3244
 |  Abstract »  |  Full Text »  |  PDF »

Efficient Nitroso Group Transfer from N-Nitrosoindoles to Nucleotides and 2'-Deoxyguanosine at Physiological pH. A NEW PATHWAY FOR N-NITROSOCOMPOUNDS TO EXERT GENOTOXICITY.

L. T. Lucas, D. Gatehouse, and D. E. G. Shuker (1999)
J. Biol. Chem. 274, 18319-18326
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-2-Activated Rat Natural Killer Cells Express Inducible Nitric Oxide Synthase That Contributes to Cytotoxic Function and Interferon-gamma Production.

M. G. Cifone, S. D'Alo, R. Parroni, D. Millimaggi, L. Biordi, S. Martinotti, and A. Santoni (1999)
Blood 93, 3876-3884
 |  Abstract »  |  Full Text »  |  PDF »

Exhaled Nitric Oxide Is Increased in Active Fibrosing Alveolitis.

P. Paredi, S. A. Kharitonov, S. Loukides, P. Pantelidis, R. M. d. Bois, and P. J. Barnes (1999)
Chest 115, 1352-1356
 |  Abstract »  |  Full Text »  |  PDF »

{beta}-Catenin Mutations Are Frequent in Hepatocellular Carcinomas but Absent in Adenomas Induced by Diethylnitrosamine in B6C3F1 Mice.

K. Ogawa, Y. Yamada, K. Kishibe, K. Ishizaki, and Y. Tokusashi (1999)
Cancer Res. 59, 1830-1833
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of Protein Kinase C Isoforms Protects RAW 264.7 Macrophages from Nitric Oxide-Induced Apoptosis: Involvement of c-Jun N-Terminal Kinase/Stress-Activated Protein Kinase, p38 Kinase, and CPP-32 Protease Pathways.

C.-D. Jun, C.-D. Oh, H.-J. Kwak, H.-O. Pae, J.-C. Yoo, B.-M. Choi, J.-S. Chun, R.-K. Park, and H.-T. Chung (1999)
J. Immunol. 162, 3395-3401
 |  Abstract »  |  Full Text »  |  PDF »

Relationship Between p53 Mutations and Inducible Nitric Oxide Synthase Expression in Human Colorectal Cancer.

S. Ambs, W. P. Bennett, W. G. Merriam, M. O. Ogunfusika, S. M. Oser, A. M. Harrington, P. G. Shields, E. Felley-Bosco, S. P. Hussain, and C. C. Harris (1999)
J Natl Cancer Inst 91, 86-88
 |  Full Text »  |  PDF »

Participation of Nitric Oxide in the Mucosal Injury of Rat Intestine Induced by Ischemia-Reperfusion.

K. Takada, K. Yamashita, Y. Sakurai-Yamashita, K. Shigematsu, Y. Hamada, K. Hioki, and K. Taniyama (1998)
J. Pharmacol. Exp. Ther. 287, 403-407
 |  Abstract »  |  Full Text »

Transfection of Inducible Nitric Oxide Synthase Gene Causes Apoptosis in Vascular Smooth Muscle Cells.

M. Iwashina, M. Shichiri, F. Marumo, and Y. Hirata (1998)
Circulation 98, 1212-1218
 |  Abstract »  |  Full Text »  |  PDF »

Up-regulation of inducible nitric oxide synthase expression in cancer-prone p53 knockout mice.

S. Ambs, M. O. Ogunfusika, W. G. Merriam, W. P. Bennett, T. R. Billiar, and C. C. Harris (1998)
PNAS 95, 8823-8828
 |  Abstract »  |  Full Text »  |  PDF »

Inducible Nitric Oxide Synthase and Nitrotyrosine Are Found in Monocytes/Macrophages and/or Astrocytes in Acute, but Not in Chronic, Multiple Sclerosis.

E. L. Oleszak, E. Zaczynska, M. Bhattacharjee, C. Butunoi, A. Legido, and C. D. Katsetos (1998)
Clin. Vaccine Immunol. 5, 438-445
 |  Abstract »  |  Full Text »

Inhibition of hypoxia-inducible factor 1 activity by nitric oxide donors in hypoxia.

K. Sogawa, K. Numayama-Tsuruta, M. Ema, M. Abe, H. Abe, and Y. Fujii-Kuriyama (1998)
PNAS 95, 7368-7373
 |  Abstract »  |  Full Text »  |  PDF »

Nitric Oxide-induced Deamination of Cytosine and Guanine in Deoxynucleosides and Oligonucleotides.

J. L. Caulfield, J. S. Wishnok, and S. R. Tannenbaum (1998)
J. Biol. Chem. 273, 12689-12695
 |  Abstract »  |  Full Text »  |  PDF »

Accelerated reaction of nitric oxide with O2 within the hydrophobic interior of biological membranes.

X. Liu, M. J. S. Miller, M. S. Joshi, D. D. Thomas, and J. R. Lancaster Jr. (1998)
PNAS 95, 2175-2179
 |  Abstract »  |  Full Text »  |  PDF »

Hepatitis B virus X protein and p53 tumor suppressor interactions in the modulation of apoptosis.

L. W. Elmore, A. R. Hancock, S.-F. Chang, X. W. Wang, S. Chang, C. P. Callahan, D. A. Geller, H. Will, and C. C. Harris (1997)
PNAS 94, 14707-14712
 |  Abstract »  |  Full Text »  |  PDF »

Irreversible Inhibition of Cytochrome P450 by Nitric Oxide.

Y. Minamiyama, S. Takemura, S. Imaoka, Y. Funae, Y. Tanimoto, and M. Inoue (1997)
J. Pharmacol. Exp. Ther. 283, 1479-1485
 |  Abstract »  |  Full Text »

Extended Abstracts.

(1997)
Toxicol Pathol 25, 674-696
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Nitric Oxide Synthases and Cardiac Muscle : Autocrine and Paracrine Influences.

J.-L. Balligand and P. J. Cannon (1997)
Arterioscler. Thromb. Vasc. Biol. 17, 1846-1858
 |  Abstract »  |  Full Text »

Somatic mutations in the p53 tumor suppressor gene in rheumatoid arthritis synovium.

G. S. Firestein, F. Echeverri, M. Yeo, N. J. Zvaifler, and D. R. Green (1997)
PNAS 94, 10895-10900
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of Reduced Striatal NMDA Excitotoxicity in Type I Nitric Oxide Synthase Knock-Out Mice.

C. Ayata, G. Ayata, H. Hara, R. T. Matthews, M. F. Beal, R. J. Ferrante, M. Endres, A. Kim, R. H. Christie, C. Waeber, et al. (1997)
J. Neurosci. 17, 6908-6917
 |  Abstract »  |  Full Text »  |  PDF »

(-)-Epigallocatechin-3-gallate Blocks the Induction of Nitric Oxide Synthase by Down-Regulating Lipopolysaccharide-Induced Activity of Transcription Factor Nuclear Factor-kappa B.

Y.-L. Lin and J.-K. Lin (1997)
Mol. Pharmacol. 52, 465-472
 |  Abstract »  |  Full Text »

Increasing cAMP Attenuates Induction of Inducible Nitric-oxide Synthase in Rat Primary Astrocytes.

K. Pahan, A. M.S. Namboodiri, F. G. Sheikh, B. T. Smith, and I. Singh (1997)
J. Biol. Chem. 272, 7786-7791
 |  Abstract »  |  Full Text »  |  PDF »

Nitric Oxide and the Neurotoxic Effects of Methamphetamine and 3,4-Methylenedioxymethamphetamine.

T. Taraska and K. T. Finnegan (1997)
J. Pharmacol. Exp. Ther. 280, 941-947
 |  Abstract »  |  Full Text »

Nitric Oxide Protects Cultured Rat Hepatocytes from Tumor Necrosis Factor-alpha -induced Apoptosis by Inducing Heat Shock Protein 70Expression.

Y.-M. Kim, M. E. de Vera, S. C. Watkins, and T. R. Billiar (1997)
J. Biol. Chem. 272, 1402-1411
 |  Abstract »  |  Full Text »  |  PDF »

Mutagenesis associated with nitric oxide production in transgenic SJL mice.

A. Gal and G. N. Wogan (1996)
PNAS 93, 15102-15107
 |  Abstract »  |  Full Text »  |  PDF »

Damage, Repair, and Mutagenesis in Nuclear Genes after Mouse Forebrain Ischemia-Reperfusion.

P. K. Liu, C. Y. Hsu, M. Dizdaroglu, R. A. Floyd, Y. W. Kow, A. Karakaya, L. E. Rabow, and J.-K. Cui (1996)
J. Neurosci. 16, 6795-6806
 |  Abstract »  |  Full Text »  |  PDF »

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