Science 18 October 1991: Vol. 254. no. 5030, pp. 432 - 437 DOI: 10.1126/science.1718042

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Articles

Facilitatory Actions of Serotonin Type 3 Receptors on GABAergic Inhibitory Synaptic Transmission in the Spinal Superficial Dorsal Horn.

T. Fukushima, T. Ohtsubo, M. Tsuda, Y. Yanagawa, and Y. Hori (2009)
J Neurophysiol 102, 1459-1471
 |  Abstract »  |  Full Text »  |  PDF »

Selective Inhibition of Acetylcholine-Evoked Responses of {alpha}7 Neuronal Nicotinic Acetylcholine Receptors by Novel tris- and tetrakis-Azaaromatic Quaternary Ammonium Antagonists.

G. Y. Lopez-Hernandez, J. S. Thinschmidt, G. Zheng, Z. Zhang, P. A. Crooks, L. P. Dwoskin, and R. L. Papke (2009)
Mol. Pharmacol. 76, 652-666
 |  Abstract »  |  Full Text »  |  PDF »

Ligand-Gated Chloride Channels Are Receptors for Biogenic Amines in C. elegans.

N. Ringstad, N. Abe, and H. R. Horvitz (2009)
Science 325, 96-100
 |  Abstract »  |  Full Text »  |  PDF »

Chromogranin A Regulates Renal Function by Triggering Weibel-Palade Body Exocytosis.

Y. Chen, M. Mahata, F. Rao, S. Khandrika, M. Courel, M. M. Fung, K. Zhang, M. Stridsberg, M. G. Ziegler, B. A. Hamilton, et al. (2009)
J. Am. Soc. Nephrol. 20, 1623-1632
 |  Abstract »  |  Full Text »  |  PDF »

Colchicine: A Novel Positive Allosteric Modulator of the Human 5-Hydroxytryptamine3A Receptor.

A. N. de Oliveira-Pierce, R. Zhang, and T. K. Machu (2009)
J. Pharmacol. Exp. Ther. 329, 838-847
 |  Abstract »  |  Full Text »  |  PDF »

Acute Alcohol Action and Desensitization of Ligand-Gated Ion Channels.

A. M. Dopico and D. M. Lovinger (2009)
Pharmacol. Rev. 61, 98-114
 |  Abstract »  |  Full Text »  |  PDF »

Potentiation of {alpha}7 nicotinic acetylcholine receptors via an allosteric transmembrane site.

G. T. Young, R. Zwart, A. S. Walker, E. Sher, and N. S. Millar (2008)
PNAS 105, 14686-14691
 |  Abstract »  |  Full Text »  |  PDF »

On the voltage-dependent Ca2+ block of serotonin 5-HT3 receptors: a critical role of intracellular phosphates.

Y. Noam, W. J. Wadman, and J. A. van Hooft (2008)
J. Physiol. 586, 3629-3638
 |  Abstract »  |  Full Text »  |  PDF »

Structural Determinants of Ca2+ Permeability and Conduction in the Human 5-Hydroxytryptamine Type 3A Receptor.

M. R. Livesey, M. A. Cooper, T. Z. Deeb, J. E. Carland, J. Kozuska, Tim. G. Hales, J. J. Lambert, and J. A. Peters (2008)
J. Biol. Chem. 283, 19301-19313
 |  Abstract »  |  Full Text »  |  PDF »

High Affinity Binding of Epibatidine to Serotonin Type 3 Receptors.

R. C. Drisdel, D. Sharp, T. Henderson, T. G. Hales, and W. N. Green (2008)
J. Biol. Chem. 283, 9659-9665
 |  Abstract »  |  Full Text »  |  PDF »

Arginine 246 of the Pretransmembrane Domain 1 Region Alters 2,2,2-Trichloroethanol Action in the 5-Hydroxytryptamine3A Receptor.

X.-Q. Hu and R. W. Peoples (2008)
J. Pharmacol. Exp. Ther. 324, 1011-1018
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of 5-HT3 receptor desensitization by the light chain of microtubule-associated protein 1B expressed in HEK 293 cells.

H. Sun, X.-Q. Hu, M. B. Emerit, J. C. Schoenebeck, C. E. Kimmel, R. W. Peoples, A. Miko, and L. Zhang (2008)
J. Physiol. 586, 751-762
 |  Abstract »  |  Full Text »  |  PDF »

Modular Design of Cys-loop Ligand-gated Ion Channels: Functional 5-HT3 and GABA {rho}1 Receptors Lacking the Large Cytoplasmic M3M4 Loop.

M. Jansen, M. Bali, and M. H. Akabas (2008)
J. Gen. Physiol. 131, 137-146
 |  Abstract »  |  Full Text »  |  PDF »

5-HT Receptor Regulation of Neurotransmitter Release.

K. B. Fink and M. Gothert (2007)
Pharmacol. Rev. 59, 360-417
 |  Abstract »  |  Full Text »  |  PDF »

Subunit-Dependent Modulation of the 5-Hydroxytryptamine Type 3 Receptor Open-Close Equilibrium by n-Alcohols.

D. Rusch, B. Musset, H. Wulf, A. Schuster, and D. E. Raines (2007)
J. Pharmacol. Exp. Ther. 321, 1069-1074
 |  Abstract »  |  Full Text »  |  PDF »

An Interaction Involving an Arginine Residue in the Cytoplasmic Domain of the 5-HT3A Receptor Contributes to Receptor Desensitization Mechanism.

X.-Q. Hu, H. Sun, R. W. Peoples, R. Hong, and L. Zhang (2006)
J. Biol. Chem. 281, 21781-21788
 |  Abstract »  |  Full Text »  |  PDF »

N-Terminal Domains in Mouse and Human 5-Hydroxytryptamine3A Receptors Confer Partial Agonist and Antagonist Properties to Benzylidene Analogs of Anabaseine.

R. Zhang, N. A. White, F. S. Soti, W. R. Kem, and T. K. Machu (2006)
J. Pharmacol. Exp. Ther. 317, 1276-1284
 |  Abstract »  |  Full Text »  |  PDF »

Ionotropic 5-HT3 Receptor Agonist-Induced Motor Responses in the Hindlimbs of Paraplegic Mice.

P. A. Guertin and I. Steuer (2005)
J Neurophysiol 94, 3397-3405
 |  Abstract »  |  Full Text »  |  PDF »

General Anesthetic-Induced Channel Gating Enhancement of 5-Hydroxytryptamine Type 3 Receptors Depends on Receptor Subunit Composition.

K. Solt, R. J. Stevens, P. A. Davies, and D. E. Raines (2005)
J. Pharmacol. Exp. Ther. 315, 771-776
 |  Abstract »  |  Full Text »  |  PDF »

Role of aspartate 298 in mouse 5-HT3A receptor gating and modulation by extracellular Ca2+.

X.-Q. Hu and D. M Lovinger (2005)
J. Physiol. 568, 381-396
 |  Abstract »  |  Full Text »  |  PDF »

Antiemetics of the 5-Hydroxytryptamine 3A Antagonist Class Inhibit Muscle Nicotinic Acetylcholine Receptors.

M. Paul, R. Callahan, J. Au, C. H. Kindler, and C. S. Yost (2005)
Anesth. Analg. 101, 715-721
 |  Abstract »  |  Full Text »  |  PDF »

Atomic force microscopy reveals the stoichiometry and subunit arrangement of 5-HT3 receptors.

N. P. Barrera, P. Herbert, R. M. Henderson, I. L. Martin, and J. M. Edwardson (2005)
PNAS 102, 12595-12600
 |  Abstract »  |  Full Text »  |  PDF »

A Variant C178T in the Regulatory Region of the Serotonin Receptor Gene HTR3A Modulates Neural Activation in the Human Amygdala.

T. Iidaka, N. Ozaki, A. Matsumoto, J. Nogawa, Y. Kinoshita, T. Suzuki, N. Iwata, Y. Yamamoto, T. Okada, and N. Sadato (2005)
J. Neurosci. 25, 6460-6466
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Determinants of Picrotoxin Inhibition of 5-Hydroxytryptamine Type 3 Receptors.

P. Das and G. H. Dillon (2005)
J. Pharmacol. Exp. Ther. 314, 320-328
 |  Abstract »  |  Full Text »  |  PDF »

Synthesis and Biodistribution of Radiolabeled {alpha}7 Nicotinic Acetylcholine Receptor Ligands.

M. G. Pomper, E. Phillips, H. Fan, D. J. McCarthy, R. A. Keith, J. C. Gordon, U. Scheffel, R. F. Dannals, and J. L. Musachio (2005)
J. Nucl. Med. 46, 326-334
 |  Abstract »  |  Full Text »  |  PDF »

Noninvasive Imaging of 5-HT3 Receptor Trafficking in Live Cells: FROM BIOSYNTHESIS TO ENDOCYTOSIS.

E. Ilegems, H. M. Pick, C. Deluz, S. Kellenberger, and H. Vogel (2004)
J. Biol. Chem. 279, 53346-53352
 |  Abstract »  |  Full Text »  |  PDF »

In Vivo Excitation of GABA Interneurons in the Medial Prefrontal Cortex through 5-HT3 Receptors.

M. V. Puig, N. Santana, P. Celada, G. Mengod, and F. Artigas (2004)
Cereb Cortex 14, 1365-1375
 |  Abstract »  |  Full Text »  |  PDF »

The Role of Palmitoylation in Functional Expression of Nicotinic {alpha}7 Receptors.

R. C. Drisdel, E. Manzana, and W. N. Green (2004)
J. Neurosci. 24, 10502-10510
 |  Abstract »  |  Full Text »  |  PDF »

Acetaminophen: A Central Analgesic Drug That Involves a Spinal Tropisetron-Sensitive, Non-5-HT3 Receptor-Mediated Effect.

F. Libert, J. Bonnefont, E. Bourinet, E. Doucet, A. Alloui, M. Hamon, J. Nargeot, and A. Eschalier (2004)
Mol. Pharmacol. 66, 728-734
 |  Abstract »  |  Full Text »  |  PDF »

Minimal Structural Rearrangement of the Cytoplasmic Pore during Activation of the 5-HT3A Receptor.

S. Panicker, H. Cruz, C. Arrabit, K. F. Suen, and P. A. Slesinger (2004)
J. Biol. Chem. 279, 28149-28158
 |  Abstract »  |  Full Text »  |  PDF »

Uropathic Observations in Mice Expressing a Constitutively Active Point Mutation in the 5-HT3A Receptor Subunit.

A. Bhattacharya, H. Dang, Q.-M. Zhu, B. Schnegelsberg, N. Rozengurt, G. Cain, R. Prantil, D. A. Vorp, N. Guy, D. Julius, et al. (2004)
J. Neurosci. 24, 5537-5548
 |  Abstract »  |  Full Text »  |  PDF »

A TM2 Residue in the {beta}1 Subunit Determines Spontaneous Opening of Homomeric and Heteromeric {gamma}-Aminobutyric Acid-gated Ion Channels.

A. Miko, E. Werby, H. Sun, J. Healey, and L. Zhang (2004)
J. Biol. Chem. 279, 22833-22840
 |  Abstract »  |  Full Text »  |  PDF »

Evidence that the TM1-TM2 Loop Contributes to the {rho}1 GABA Receptor Pore.

N. Filippova, V. E. Wotring, and D. S. Weiss (2004)
J. Biol. Chem. 279, 20906-20914
 |  Abstract »  |  Full Text »  |  PDF »

Pharmacological Properties of {alpha}9{alpha}10 Nicotinic Acetylcholine Receptors Revealed by Heterologous Expression of Subunit Chimeras.

E. R. Baker, R. Zwart, E. Sher, and N. S. Millar (2004)
Mol. Pharmacol. 65, 453-460
 |  Abstract »  |  Full Text »  |  PDF »

Arginine 222 in the Pre-transmembrane Domain 1 of 5-HT3A Receptors Links Agonist Binding to Channel Gating.

X.-Q. Hu, L. Zhang, R. R. Stewart, and F. F. Weight (2003)
J. Biol. Chem. 278, 46583-46589
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of 5-HT3 Receptor-mediated Response and Trafficking by Activation of Protein Kinase C.

H. Sun, X.-Q. Hu, E. M. Moradel, F. F. Weight, and L. Zhang (2003)
J. Biol. Chem. 278, 34150-34157
 |  Abstract »  |  Full Text »  |  PDF »

Improvements in Hippocampal-Dependent Learning and Decremental Attention in 5-HT3 Receptor Overexpressing Mice.

A. V. Harrell and A. M. Allan (2003)
Learn. Mem. 10, 410-419
 |  Abstract »  |  Full Text »  |  PDF »

Cell Surface Expression of 5-Hydroxytryptamine Type 3 Receptors Is Controlled by an Endoplasmic Reticulum Retention Signal.

G. W. Boyd, A. I. Doward, E. F. Kirkness, N. S. Millar, and C. N. Connolly (2003)
J. Biol. Chem. 278, 27681-27687
 |  Abstract »  |  Full Text »  |  PDF »

Nongenomic Steroid Action: Controversies, Questions, and Answers.

R. M. LOSEL, E. FALKENSTEIN, M. FEURING, A. SCHULTZ, H.-C. TILLMANN, K. ROSSOL-HASEROTH, and M. WEHLING (2003)
Physiol Rev 83, 965-1016
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of the Ligand-binding Site of the Serotonin 5-HT3 Receptor: THE ROLE OF GLUTAMATE RESIDUES 97, 224, AND 235.

C. Schreiter, R. Hovius, M. Costioli, H. Pick, S. Kellenberger, L. Schild, and H. Vogel (2003)
J. Biol. Chem. 278, 22709-22716
 |  Abstract »  |  Full Text »  |  PDF »

Variations in the 5-Hydroxytryptamine Type 3B Receptor Gene as Predictors of the Efficacy of Antiemetic Treatment in Cancer Patients.

P.-B. Tremblay, R. Kaiser, O. Sezer, N. Rosler, C. Schelenz, K. Possinger, I. Roots, and J. Brockmoller (2003)
J. Clin. Oncol. 21, 2147-2155
 |  Abstract »  |  Full Text »  |  PDF »

Direct Interaction of Serotonin Type 3 Receptor Ligands with Recombinant and Native alpha 9alpha 10-Containing Nicotinic Cholinergic Receptors.

C. V. Rothlin, M. I. Lioudyno, A. F. Silbering, P. V. Plazas, M. E. G. Casati, E. Katz, P. S. Guth, and A. B. Elgoyhen (2003)
Mol. Pharmacol. 63, 1067-1074
 |  Abstract »  |  Full Text »  |  PDF »

Ca2+ Ions Block and Permeate Serotonin 5-HT3 Receptor Channels in Rat Hippocampal Interneurons.

J. A. van Hooft and W. J. Wadman (2003)
J Neurophysiol 89, 1864-1869
 |  Abstract »  |  Full Text »  |  PDF »

Intracellular Cross Talk and Physical Interaction between Two Classes of Neurotransmitter-Gated Channels.

E. Boue-Grabot, C. Barajas-Lopez, Y. Chakfe, D. Blais, D. Belanger, M. B. Emerit, and P. Seguela (2003)
J. Neurosci. 23, 1246-1253
 |  Abstract »  |  Full Text »  |  PDF »

Changes in Conformation and Subcellular Distribution of alpha 4beta 2 Nicotinic Acetylcholine Receptors Revealed by Chronic Nicotine Treatment and Expression of Subunit Chimeras.

P. C. Harkness and N. S. Millar (2002)
J. Neurosci. 22, 10172-10181
 |  Abstract »  |  Full Text »  |  PDF »

Inhibitory interactions between 5-HT3 and P2X channels in submucosal neurons.

C. Barajas-Lopez, L. M. Montano, and R. Espinosa-Luna (2002)
Am J Physiol Gastrointest Liver Physiol 283, G1238-G1248
 |  Abstract »  |  Full Text »  |  PDF »

Expression and function of 5-HT3 receptors in the enteric neurons of mice lacking the serotonin transporter.

M.-T. Liu, S. Rayport, Y. Jiang, D. L. Murphy, and M. D. Gershon (2002)
Am J Physiol Gastrointest Liver Physiol 283, G1398-G1411
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Molecular Basis for Differential Sensitivity of the Serotonin Type 3A Receptor to Ethanol in the Absence and Presence of Agonist.

L. Zhang, M. Hosoi, M. Fukuzawa, H. Sun, R. R. Rawlings, and F. F. Weight (2002)
J. Biol. Chem. 277, 46256-46264
 |  Abstract »  |  Full Text »  |  PDF »

Serotonin 5-HT3 receptors in rat CA1 hippocampal interneurons: functional and molecular characterization.

S. N Sudweeks, J. A van Hooft, and J. L Yakel (2002)
J. Physiol. 544, 715-726
 |  Abstract »  |  Full Text »  |  PDF »

The beta Subunit Determines the Ion Selectivity of the GABAA Receptor.

M. L. Jensen, D. B. Timmermann, T. H. Johansen, A. Schousboe, T. Varming, and P. K. Ahring (2002)
J. Biol. Chem. 277, 41438-41447
 |  Abstract »  |  Full Text »  |  PDF »

Electrophysiological Evidence for Expression of Glycine Receptors in Freshly Isolated Neurons from Nucleus Accumbens.

G. Martin and G. R. Siggins (2002)
J. Pharmacol. Exp. Ther. 302, 1135-1145
 |  Abstract »  |  Full Text »  |  PDF »

5-HT3 Receptors Mediate Serotonergic Fast Synaptic Excitation of Neocortical Vasoactive Intestinal Peptide/Cholecystokinin Interneurons.

I. Ferezou, B. Cauli, E. L. Hill, J. Rossier, E. Hamel, and B. Lambolez (2002)
J. Neurosci. 22, 7389-7397
 |  Abstract »  |  Full Text »  |  PDF »

Differential Composition of 5-Hydroxytryptamine3 Receptors Synthesized in the Rat CNS and Peripheral Nervous System.

M. Morales and S.-D. Wang (2002)
J. Neurosci. 22, 6732-6741
 |  Abstract »  |  Full Text »  |  PDF »

Identification of transcriptional targets for Six5: implication for the pathogenesis of myotonic dystrophy type 1.

S. Sato, M. Nakamura, D. H. Cho, S. J. Tapscott, H. Ozaki, and K. Kawakami (2002)
Hum. Mol. Genet. 11, 1045-1058
 |  Abstract »  |  Full Text »  |  PDF »

Cation-selective Mutations in the M2 Domain of the Inhibitory Glycine Receptor Channel Reveal Determinants of Ion-Charge Selectivity.

A. Keramidas, A. J. Moorhouse, K. D. Pierce, P. R. Schofield, and P. H. Barry (2002)
J. Gen. Physiol. 119, 393-410
 |  Abstract »  |  Full Text »  |  PDF »

Serotonin 5-HT3 receptors on mechanosensitive neurons with cardiac afferents.

P. Linz and R. Veelken (2002)
Am J Physiol Heart Circ Physiol 282, H1828-H1835
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Structure and Physiological Function of Chloride Channels.

T. J. Jentsch, V. Stein, F. Weinreich, and A. A. Zdebik (2002)
Physiol Rev 82, 503-568
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for a Centrally Located Gate in the Pore of a Serotonin-Gated Ion Channel.

S. Panicker, H. Cruz, C. Arrabit, and P. A. Slesinger (2002)
J. Neurosci. 22, 1629-1639
 |  Abstract »  |  Full Text »  |  PDF »

The 5-HT3 Subtype of Serotonin Receptor Contributes to Nociceptive Processing via a Novel Subset of Myelinated and Unmyelinated Nociceptors.

K. P. Zeitz, N. Guy, A. B. Malmberg, S. Dirajlal, W. J. Martin, L. Sun, D. W. Bonhaus, C. L. Stucky, D. Julius, and A. I. Basbaum (2002)
J. Neurosci. 22, 1010-1019
 |  Abstract »  |  Full Text »  |  PDF »

Benzylidene Analogs of Anabaseine Display Partial Agonist and Antagonist Properties at the Mouse 5-Hydroxytryptamine3A Receptor.

T. K. Machu, M. E. Hamilton, T. F. Frye, C. L. Shanklin, M. C. Harris, H. Sun, T. E. Tenner Jr., F. S. Soti, and W. R. Kem (2001)
J. Pharmacol. Exp. Ther. 299, 1112-1119
 |  Abstract »  |  Full Text »  |  PDF »

Structural and Electrostatic Properties of the 5-HT3 Receptor Pore Revealed by Substituted Cysteine Accessibility Mutagenesis.

D. C. Reeves, E. N. Goren, M. H. Akabas, and S. C. R. Lummis (2001)
J. Biol. Chem. 276, 42035-42042
 |  Abstract »  |  Full Text »  |  PDF »

Mutations in the Caenorhabditis elegans Serotonin Reuptake Transporter MOD-5 Reveal Serotonin-Dependent and -Independent Activities of Fluoxetine.

R. Ranganathan, E. R. Sawin, C. Trent, and H. R. Horvitz (2001)
J. Neurosci. 21, 5871-5884
 |  Abstract »  |  Full Text »  |  PDF »

A Single Amino-Acid in the TM1 Domain Is an Important Determinant of the Desensitization Kinetics of Recombinant Human and Guinea Pig {alpha}-Homomeric 5-Hydroxytryptamine Type 3 Receptors.

N. Lobitz, G. Gisselmann, H. Hatt, and C. H. Wetzel (2001)
Mol. Pharmacol. 59, 844-851
 |  Abstract »  |  Full Text »

Presynaptic 5-HT3 receptor-mediated modulation of synaptic GABA release in the mechanically dissociated rat amygdala neurons.

S. Koyama, N. Matsumoto, C. Kubo, and N. Akaike (2000)
J. Physiol. 529, 373-383
 |  Abstract »  |  Full Text »  |  PDF »

The Multiplicity of Serotonin Receptors: Uselessly Diverse Molecules or an Embarrassment of Riches?.

B. L. Roth, E. Lopez, S. Patel, and W. K. Kroeze (2000)
Neuroscientist 6, 252-262
 |  Abstract »  |  PDF »

Probing the Role of a Conserved M1 Proline Residue in 5-Hydroxytryptamine3 Receptor Gating.

H. Dang, P. M. England, S. S. Farivar, D. A. Dougherty, and H. A. Lester (2000)
Mol. Pharmacol. 57, 1114-1122
 |  Abstract »  |  Full Text »

Importance of Phenylalanine 107 in Agonist Recognition by the 5-Hydroxytryptamine3A Receptor.

L. J. Steward, F. G. Boess, J. A. Steele, D. Liu, N. Wong, and I. L. Martin (2000)
Mol. Pharmacol. 57, 1249-1255
 |  Abstract »  |  Full Text »

The Role of Tryptophan Residues in the 5-Hydroxytryptamine3 Receptor Ligand Binding Domain.

A. D. Spier and S. C. R. Lummis (2000)
J. Biol. Chem. 275, 5620-5625
 |  Abstract »  |  Full Text »  |  PDF »

Nondepolarizing Neuromuscular Blockers Inhibit the Serotonin-Type 3A Receptor Expressed in Xenopus Oocytes.

K. T. Min, C. L. Wu, and J. Yang (2000)
Anesth. Analg. 90, 476
 |  Abstract »  |  Full Text »  |  PDF »

The 4'lysine in the putative channel lining domain affects desensitization but not the single-channel conductance of recombinant homomeric 5-HT3A receptors.

M. J Gunthorpe, J. A Peters, C. H Gill, J. J Lambert, and S. C R Lummis (2000)
J. Physiol. 522, 187-198
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Serotonin Receptors Modulates Synaptic Transmission in Rat Cerebral Cortex.

F.-M. Zhou and J. J. Hablitz (1999)
J Neurophysiol 82, 2989-2999
 |  Abstract »  |  Full Text »  |  PDF »

The Pharmacological and Functional Characteristics of the Serotonin 5-HT3A Receptor Are Specifically Modified by a 5-HT3B Receptor Subunit.

A. E. Dubin, R. Huvar, M. R. D'Andrea, J. Pyati, J. Y. Zhu, K. C. Joy, S. J. Wilson, J. E. Galindo, C. A. Glass, L. Luo, et al. (1999)
J. Biol. Chem. 274, 30799-30810
 |  Abstract »  |  Full Text »  |  PDF »

Inward Currents in Neurons from Newborn Guinea Pig Intestine: Mediation by 5-Hydroxytryptamine Type 3 Receptors.

J. Zhai, M. D. Gershon, J. H. Walsh, H. C. Wong, and A. L. Kirchgessner (1999)
J. Pharmacol. Exp. Ther. 291, 374-382
 |  Abstract »  |  Full Text »

Up-regulation of Cell-surface alpha 4beta 2 Neuronal Nicotinic Receptors by Lower Temperature and Expression of Chimeric Subunits.

S. T. Cooper, P. C. Harkness, E. R. Baker, and N. S. Millar (1999)
J. Biol. Chem. 274, 27145-27152
 |  Abstract »  |  Full Text »  |  PDF »

Diltiazem causes open channel block of recombinant 5-HT3 receptors.

M. J Gunthorpe and S. C R Lummis (1999)
J. Physiol. 519, 713-722
 |  Abstract »  |  Full Text »  |  PDF »

Competitive Antagonism of the Mouse 5-Hydroxytryptamine3 Receptor by Bisindolylmaleimide I, a "Selective" Protein Kinase C Inhibitor.

S. J. Coultrap, H. Sun, T. E. Tenner Jr., and T. K. Machu (1999)
J. Pharmacol. Exp. Ther. 290, 76-82
 |  Abstract »  |  Full Text »

Inhibitory Effect of Ondansetron on Glycine Response of Dissociated Rat Hippocampal Neurons.

J. H. Ye, R. Schaefer, W.-H. Wu, P. L. Liu, V. K. Zbuzek, and J. J. Mcardle (1999)
J. Pharmacol. Exp. Ther. 290, 104-111
 |  Abstract »  |  Full Text »

Ion Channels in Presynaptic Nerve Terminals and Control of Transmitter Release.

A. Meir, S. Ginsburg, A. Butkevich, S. G. Kachalsky, I. Kaiserman, R. Ahdut, S. Demirgoren, and R. Rahamimoff (1999)
Physiol Rev 79, 1019-1088
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Determinants of (+)-Tubocurarine Binding at Recombinant 5-Hydroxytryptamine3A Receptor Subunits.

A. G. Hope, D. Belelli, I. D. Mair, J. J. Lambert, and J. A. Peters (1999)
Mol. Pharmacol. 55, 1037-1043
 |  Abstract »  |  Full Text »

Acid-Evoked Currents in Cardiac Sensory Neurons : A Possible Mediator of Myocardial Ischemic Sensation.

C. J. Benson, S. P. Eckert, and E. W. McCleskey (1999)
Circ. Res. 84, 921-928
 |  Abstract »  |  Full Text »  |  PDF »

Structural Features of the Ligand-binding Domain of the Serotonin 5HT3 Receptor.

D. Yan, M. K. Schulte, K. E. Bloom, and M. M. White (1999)
J. Biol. Chem. 274, 5537-5541
 |  Abstract »  |  Full Text »  |  PDF »

The Nicotinic alpha 4 Receptor Subunit Contributes to the Lining of the Ion Channel Pore When Expressed with the 5-HT3 Receptor Subunit.

S. Kriegler, S. Sudweeks, and J. L. Yakel (1999)
J. Biol. Chem. 274, 3934-3936
 |  Abstract »  |  Full Text »  |  PDF »

The alpha 9 Nicotinic Acetylcholine Receptor Shares Pharmacological Properties with Type A gamma -Aminobutyric Acid, Glycine, and Type 3 Serotonin Receptors.

C. V. Rothlin, E. Katz, M. Verbitsky, and A. B. Elgoyhen (1999)
Mol. Pharmacol. 55, 248-254
 |  Abstract »  |  Full Text »

Promiscuous coassembly of serotonin 5-HT3 and nicotinic alpha 4 receptor subunits into Ca2+-permeable ion channels.

J. A. van Hooft, A. D. Spier, J. L. Yakel, S. C. R. Lummis, and H. P. M. Vijverberg (1998)
PNAS 95, 11456-11461
 |  Abstract »  |  Full Text »  |  PDF »

Functional Antagonism of Gonadal Steroids at the 5-Hydroxytryptamine Type 3 Receptor.

C. H. R. Wetzel, B. Hermann, C. Behl, E. Pestel, G. Rammes, W. Zieglgänsberger, F. Holsboer, and R. Rupprecht (1998)
Mol. Endocrinol. 12, 1441-1451
 |  Abstract »  |  Full Text »

Neuronal Expression of the 5HT3 Serotonin Receptor Gene Requires Nuclear Factor 1 Complexes.

F. K. Bedford, D. Julius, and H. A. Ingraham (1998)
J. Neurosci. 18, 6186-6194
 |  Abstract »  |  Full Text »  |  PDF »

Inactivation of a Serotonin-Gated Ion Channel by a Polypeptide Toxin from Marine Snails.

L. J. England, J. Imperial, R. Jacobsen, A. G. Craig, J. Gulyas, M. Akhtar, J. Rivier, D. Julius, and B. M. Olivera (1998)
Science 281, 575-578
 |  Abstract »  |  Full Text »

A Mutation Affecting Dihydropyridine-Sensitive Current Levels and Activation Kinetics in Drosophila Muscle and Mammalian Heart Calcium Channels.

D. Ren, H. Xu, D. F. Eberl, M. Chopra, and L. M. Hall (1998)
J. Neurosci. 18, 2335-2341
 |  Abstract »  |  Full Text »  |  PDF »

Ion permeation and conduction in a human recombinant 5-HT3 receptor subunit (h5-HT3A).

A M Brown, A G Hope, J J Lambert, and J A Peters (1998)
J. Physiol. 507, 653-665
 |  Abstract »  |  Full Text »  |  PDF »

Substitutions of the Highly Conserved M2 Leucine Create Spontaneously Opening rho 1 gamma -Aminobutyric Acid Receptors.

Y. Chang and D. S. Weiss (1998)
Mol. Pharmacol. 53, 511-523
 |  Abstract »  |  Full Text »

Two mechanisms for inward rectification of current flow through the purinoceptor P2X2 class of ATP-gated channels.

Z. Zhou and R. I Hume (1998)
J. Physiol. 507, 353-364
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Cloning, Functional Expression, and Pharmacological Characterization of 5-Hydroxytryptamine3 Receptor cDNA and Its Splice Variants from Guinea Pig.

S. Lankiewicz, N. Lobitz, C. H. R. Wetzel, R. Rupprecht, G. Gisselmann, and H. Hatt (1998)
Mol. Pharmacol. 53, 202-212
 |  Abstract »  |  Full Text »

Hippocampal Interneurons Are Excited Via Serotonin-Gated Ion Channels.

L. L. McMahon and J. A. Kauer (1997)
J Neurophysiol 78, 2493-2502
 |  Abstract »  |  Full Text »  |  PDF »

Developing Neonatal Rat Sympathetic and Sensory Neurons Differ in Their Regulation of 5-HT3 Receptor Expression.

M. Rosenberg, B. Pie, and E. Cooper (1997)
J. Neurosci. 17, 6629-6638
 |  Abstract »  |  Full Text »  |  PDF »

The Role of the Cystine Loop in Acetylcholine Receptor Assembly.

W. N. Green and C. P. Wanamaker (1997)
J. Biol. Chem. 272, 20945-20953
 |  Abstract »  |  Full Text »  |  PDF »

Agonist-induced closure of constitutively open gamma -aminobutyric acid channels with mutated M2 domains.

Z.-H. Pan, D. Zhang, X. Zhang, and S. A. Lipton (1997)
PNAS 94, 6490-6495
 |  Abstract »  |  Full Text »  |  PDF »

Electrophysiological Analysis of Dorsal Root Ganglion Neurons Pre- and Post-Coexpression of Green Fluorescent Protein and Functional 5-HT3 Receptor.

G. M. Smith, R. L. Berry, J. Yang, and D. Tanelian (1997)
J Neurophysiol 77, 3115-3121
 |  Abstract »  |  Full Text »  |  PDF »

The 5-HT3 Receptor Is Present in Different Subpopulations of GABAergic Neurons in the Rat Telencephalon.

M. Morales and F. E. Bloom (1997)
J. Neurosci. 17, 3157-3167
 |  Abstract »  |  Full Text »  |  PDF »

Formation of Oligomers Containing the beta 3 and beta 4 Subunits of the Rat Nicotinic Receptor.

J. R. Forsayeth and E. Kobrin (1997)
J. Neurosci. 17, 1531-1538
 |  Abstract »  |  Full Text »  |  PDF »

Platelet Activation in Carotid Sinuses Triggers Reflex Sympathoinhibition and Hypotension.

H. Z. Mao, Z. Li, and M. W. Chapleau (1996)
Hypertension 27, 584-590
 |  Abstract »  |  Full Text »

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