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Science 11 October 1991:
Vol. 254. no. 5029, pp. 221 - 225
DOI: 10.1126/science.1925579
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Articles

Science, Vol 254, Issue 5029, 221-225
Copyright © 1991 by American Association for the Advancement of Science

articles

Toward cloning and mapping the genome of Drosophila

J Merriam, M Ashburner, DL Hartl, and FC Kafatos

Department of Biology, University of California, Los Angeles 90024.

An ultimate goal of Drosophila genetics is to identify and define the functions of all the genes in the organism. Traditional approaches based on the isolation of mutant genes have been extraordinary fruitful. Recent advances in the manipulation and analysis of large DNA fragments have made it possible to develop detailed molecular maps of the Drosophila genome as the initial steps in determining the complete DNA sequence.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Map Position and Expression of the Genes in the 38 Region of Drosophila.
H. Butler, S. Levine, X. Wang, S. Bonyadi, G. Fu, P. Lasko, B. Suter, and R. Doerig (2001)
Genetics 158, 1597-1614
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Unusually High Recombination Rate Detected in the Sex Locus Region of the Honey Bee (Apis mellifera).
M. Beye, G. J. Hunt, R. E. Page, M. K. Fondrk, L. Grohmann, and R. F. A. Moritz (1999)
Genetics 153, 1701-1708
   Abstract »    Full Text »
A Dense Genetic Map of the Silkworm, Bombyx mori, Covering All Chromosomes Based on 1018 Molecular Markers.
Y. Yasukochi (1998)
Genetics 150, 1513-1525
   Abstract »    Full Text »
Loss of the Tight Junction MAGUK ZO-1 in Breast Cancer : Relationship to Glandular Differentiation and Loss ofHeterozygosity.
K. B. Hoover, S.-Y. Liao, and P. J. Bryant (1998)
Am. J. Pathol. 153, 1767-1773
   Abstract »    Full Text »    PDF »
Molecular Medicine: A Spin-off From the Helix.
C. T. Caskey (1993)
JAMA 269, 1986-1992
   Abstract »    PDF »


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