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Science 4 October 1991:
Vol. 254. no. 5028, pp. 43 - 50
DOI: 10.1126/science.1925560
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Articles

Science, Vol 254, Issue 5028, 43-50
Copyright © 1991 by American Association for the Advancement of Science

articles

Echo-planar imaging: magnetic resonance imaging in a fraction of a second

MK Stehling, R Turner, and P Mansfield

Department of Cardiology, Friedrich Alexander University, Erlangen, Germany.

Progress has recently been made in implementing magnetic resonance imaging (MRI) techniques that can be used to obtain images in a fraction of a second rather than in minutes. Echo-planar imaging (EPI) uses only one nuclear spin excitation per image and lends itself to a variety of critical medical and scientific applications. Among these are evaluation of cardiac function in real time, mapping of water diffusion and temperature in tissue, mapping of organ blood pool and perfusion, functional imaging of the central nervous system, depiction of blood and cerebrospinal fluid flow dynamics, and movie imaging of the mobile fetus in utero. Through shortened patient examination times, higher patient throughput, and lower cost per MRI examination, EPI may become a powerful tool for early diagnosis of some common and potentially treatable diseases such as ischemic heart disease, stroke, and cancer.


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