Science 13 September 1991: Vol. 253. no. 5025, pp. 1280 - 1283 DOI: 10.1126/science.1891716

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Articles

The Interleukin-8 Pathway in Cancer.

D. J.J. Waugh and C. Wilson (2008)
Clin. Cancer Res. 14, 6735-6741
 |  Abstract »  |  Full Text »  |  PDF »

Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation.

P. Proost, T. Loos, A. Mortier, E. Schutyser, M. Gouwy, S. Noppen, C. Dillen, I. Ronsse, R. Conings, S. Struyf, et al. (2008)
J. Exp. Med. 205, 2085-2097
 |  Abstract »  |  Full Text »  |  PDF »

Re-evaluation of Chicken CXCR1 Determines the True Gene Structure: CXCLi1 (K60) AND CXCLi2 (CAF/INTERLEUKIN-8) ARE LIGANDS FOR THIS RECEPTOR.

T. Y. Poh, J. Pease, J. R. Young, N. Bumstead, and P. Kaiser (2008)
J. Biol. Chem. 283, 16408-16415
 |  Abstract »  |  Full Text »  |  PDF »

Abnormal in vitro CXCR2 modulation and defective cationic ion transporter expression on polymorphonuclear neutrophils responsible for hyporesponsiveness to IL-8 stimulation in patients with active systemic lupus erythematosus.

S.-C. Hsieh, T.-H. Wu, C.-Y. Tsai, K.-J. Li, M.-C. Lu, C.-H. Wu, and C.-L. Yu (2008)
Rheumatology 47, 150-157
 |  Abstract »  |  Full Text »  |  PDF »

Transactivation of Vascular Endothelial Growth Factor Receptor-2 by Interleukin-8 (IL-8/CXCL8) Is Required for IL-8/CXCL8-induced Endothelial Permeability.

M. L. Petreaca, M. Yao, Y. Liu, K. DeFea, and M. Martins-Green (2007)
Mol. Biol. Cell 18, 5014-5023
 |  Abstract »  |  Full Text »  |  PDF »

Platelet Factor-4 Variant Chemokine CXCL4L1 Inhibits Melanoma and Lung Carcinoma Growth and Metastasis by Preventing Angiogenesis.

S. Struyf, M. D. Burdick, E. Peeters, K. Van den Broeck, C. Dillen, P. Proost, J. Van Damme, and R. M. Strieter (2007)
Cancer Res. 67, 5940-5948
 |  Abstract »  |  Full Text »  |  PDF »

Murine CXCR1 Is a Functional Receptor for GCP-2/CXCL6 and Interleukin-8/CXCL8.

X. Fan, A. C. Patera, A. Pong-Kennedy, G. Deno, W. Gonsiorek, D. J. Manfra, G. Vassileva, M. Zeng, C. Jackson, L. Sullivan, et al. (2007)
J. Biol. Chem. 282, 11658-11666
 |  Abstract »  |  Full Text »  |  PDF »

CXCR1 and CXCR2 Activation and Regulation: ROLE OF ASPARTATE 199 OF THE SECOND EXTRACELLULAR LOOP OF CXCR2 IN CXCL8-MEDIATED RAPID RECEPTOR INTERNALIZATION.

M. W. Nasser, S. K. Raghuwanshi, K. M. Malloy, P. Gangavarapu, J.-Y. Shim, K. Rajarathnam, and R. M. Richardson (2007)
J. Biol. Chem. 282, 6906-6915
 |  Abstract »  |  Full Text »  |  PDF »

99mTc-Labeled Interleukin 8 for the Scintigraphic Detection of Infection and Inflammation: First Clinical Evaluation.

C. P. Bleeker-Rovers, H. J.J.M. Rennen, O. C. Boerman, A. B. Wymenga, E. P. Visser, J. H. Bakker, J. W.M. van der Meer, F. H.M. Corstens, and W. J.G. Oyen (2007)
J. Nucl. Med. 48, 337-343
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-8: novel roles in human airway smooth muscle cell contraction and migration.

V. Govindaraju, M.-C. Michoud, M. Al-Chalabi, P. Ferraro, W. S. Powell, and J. G. Martin (2006)
Am J Physiol Cell Physiol 291, C957-C965
 |  Abstract »  |  Full Text »  |  PDF »

Associations of Classic Kaposi Sarcoma with Common Variants in Genes that Modulate Host Immunity..

E. E. Brown, D. Fallin, I. Ruczinski, A. Hutchinson, B. Staats, F. Vitale, C. Lauria, D. Serraino, G. Rezza, G. Mbisa, et al. (2006)
Cancer Epidemiol. Biomarkers Prev. 15, 926-934
 |  Abstract »  |  Full Text »  |  PDF »

Neutrophil chemorepulsion in defined interleukin-8 gradients in vitro and in vivo.

W. G. Tharp, R. Yadav, D. Irimia, A. Upadhyaya, A. Samadani, O. Hurtado, S-Y. Liu, S. Munisamy, D. M. Brainard, M. J. Mahon, et al. (2006)
J. Leukoc. Biol. 79, 539-554
 |  Abstract »  |  Full Text »  |  PDF »

Neutrophils Accelerate Macrophage-Mediated Digestion of Apoptotic Cells In Vivo as Well as In Vitro.

T. Iyoda, K. Nagata, M. Akashi, and Y. Kobayashi (2005)
J. Immunol. 175, 3475-3483
 |  Abstract »  |  Full Text »  |  PDF »

The Macrophage-derived Lectin, MNCF, Activates Neutrophil Migration through a Pertussis Toxin-sensitive Pathway.

A. N. Moreno, G. Pereira-da-Silva, C. Oliver, M. C. Jamur, A. Panunto-Castelo, and M. C. Roque-Barreira (2005)
J. Histochem. Cytochem. 53, 715-723
 |  Abstract »  |  Full Text »  |  PDF »

Differential Expression of Interleukin-8 and Its Receptors in the Neuroendocrine and Non-Neuroendocrine Compartments of Prostate Cancer.

J. Huang, J. L. Yao, L. Zhang, P. A. Bourne, A. M. Quinn, P. A. di Sant'Agnese, and J. E. Reeder (2005)
Am. J. Pathol. 166, 1807-1815
 |  Abstract »  |  Full Text »  |  PDF »

The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis.

D. J. Brat, A. C. Bellail, and E. G. Van Meir (2005)
Neuro-oncol 7, 122-133
 |  Abstract »  |  PDF »

IL-8 and its CXCR1 and CXCR2 receptors participate in the control of megakaryocytic proliferation, differentiation, and ploidy in myeloid metaplasia with myelofibrosis.

S. Emadi, D. Clay, C. Desterke, B. Guerton, E. Maquarre, A. Charpentier, C. Jasmin, M.-C. Le Bousse-Kerdiles, and for the French INSERM Research Network on MMM (2005)
Blood 105, 464-473
 |  Abstract »  |  Full Text »  |  PDF »

99mTc-Labeled Interleukin-8 for Scintigraphic Detection of Pulmonary Infections.

H. J. J. M. Rennen, C. P. Bleeker-Rovers, J. E. M. van Eerd, C. Frielink, W. J. G. Oyen, F. H. M. Corstens, and O. C. Boerman (2004)
Chest 126, 1954-1961
 |  Abstract »  |  Full Text »  |  PDF »

On the Mechanism and Significance of Ligand-induced Internalization of Human Neutrophil Chemokine Receptors CXCR1 and CXCR2.

J. J. Rose, J. F. Foley, P. M. Murphy, and S. Venkatesan (2004)
J. Biol. Chem. 279, 24372-24386
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Cyclooxygenase-2-Dependent Expression of Angiogenic CXC Chemokines ENA-78/CXC Ligand (CXCL) 5 and Interleukin-8/CXCL8 in Human Non-Small Cell Lung Cancer.

M. Pold, L. X. Zhu, S. Sharma, M. D. Burdick, Y. Lin, P. P. N. Lee, A. Pold, J. Luo, K. Krysan, M. Dohadwala, et al. (2004)
Cancer Res. 64, 1853-1860
 |  Abstract »  |  Full Text »  |  PDF »

Depletion of CXCR2 Inhibits Tumor Growth and Angiogenesis in a Murine Model of Lung Cancer.

M. P. Keane, J. A. Belperio, Y. Y. Xue, M. D. Burdick, and R. M. Strieter (2004)
J. Immunol. 172, 2853-2860
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IL-15 and IL-2 oppositely regulate expression of the chemokine receptor CX3CR1.

J. Barlic, J. M. Sechler, and P. M. Murphy (2003)
Blood 102, 3494-3503
 |  Abstract »  |  Full Text »  |  PDF »

Plasma levels of interleukin-8 and expression of interleukin-8 receptors on circulating neutrophils and monocytes after cardiopulmonary bypass in children.

P. Gessler, J. Pfenninger, J.-P. Pfammatter, T. Carrel, O. Baenziger, and C. Dahinden (2003)
J. Thorac. Cardiovasc. Surg. 126, 718-725
 |  Abstract »  |  Full Text »  |  PDF »

Kinetics of 99mTc-Labeled Interleukin-8 in Experimental Inflammation and Infection.

H. J.J.M. Rennen, O. C. Boerman, W. J.G. Oyen, and F. H.M. Corstens (2003)
J. Nucl. Med. 44, 1502-1509
 |  Abstract »  |  Full Text »  |  PDF »

G protein-coupled receptors in natural killer cells.

A. A. Maghazachi (2003)
J. Leukoc. Biol. 74, 16-24
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Helicobacter pylori Infection Induces Interleukin-8 Receptor Expression in the Human Gastric Epithelium.

F. Backhed, E. Torstensson, D. Seguin, A. Richter-Dahlfors, and B. Rokbi (2003)
Infect. Immun. 71, 3357-3360
 |  Abstract »  |  Full Text »  |  PDF »

Pathophysiological roles of interleukin-8/CXCL8 in pulmonary diseases.

N. Mukaida (2003)
Am J Physiol Lung Cell Mol Physiol 284, L566-L577
 |  Abstract »  |  Full Text »  |  PDF »

Role of the Cytoplasmic Tails of CXCR1 and CXCR2 in Mediating Leukocyte Migration, Activation, and Regulation.

R. M. Richardson, R. J. Marjoram, L. S. Barak, and R. Snyderman (2003)
J. Immunol. 170, 2904-2911
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Down-Regulation of Proinflammatory Capacity During Apoptosis in Human Polymorphonuclear Leukocytes.

S. D. Kobayashi, J. M. Voyich, K. R. Braughton, and F. R. DeLeo (2003)
J. Immunol. 170, 3357-3368
 |  Abstract »  |  Full Text »  |  PDF »

A Potent and Selective Nonpeptide Antagonist of CXCR2 Inhibits Acute and Chronic Models of Arthritis in the Rabbit.

P. L. Podolin, B. J. Bolognese, J. J. Foley, D. B. Schmidt, P. T. Buckley, K. L. Widdowson, Q. Jin, J. R. White, J. M. Lee, R. B. Goodman, et al. (2002)
J. Immunol. 169, 6435-6444
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Angiogenesis by a Fragment of Human Tyrosyl-tRNA Synthetase.

K. Wakasugi, B. M. Slike, J. Hood, K. L. Ewalt, D. A. Cheresh, and P. Schimmel (2002)
J. Biol. Chem. 277, 20124-20126
 |  Abstract »  |  Full Text »  |  PDF »

Signaling Pathways Involved in IL-8-Dependent Activation of Adhesion Through Mac-1.

M. Takami, V. Terry, and L. Petruzzelli (2002)
J. Immunol. 168, 4559-4566
 |  Abstract »  |  Full Text »  |  PDF »

CXCR2 Deficiency Confers Impaired Neutrophil Recruitment and Increased Susceptibility During Toxoplasma gondii Infection.

L. Del Rio, S. Bennouna, J. Salinas, and E. Y. Denkers (2001)
J. Immunol. 167, 6503-6509
 |  Abstract »  |  Full Text »  |  PDF »

Chemokines Regulate IL-6 and IL-8 Production by Fibroblast-Like Synoviocytes from Patients with Rheumatoid Arthritis.

T. Nanki, K. Nagasaka, K. Hayashida, Y. Saita, and N. Miyasaka (2001)
J. Immunol. 167, 5381-5385
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Immobilized IL-8 Triggers Progressive Activation of Neutrophils Rolling In Vitro on P-Selectin and Intercellular Adhesion Molecule-1.

J. A. DiVietro, M. J. Smith, B. R. E. Smith, L. Petruzzelli, R. S. Larson, and M. B. Lawrence (2001)
J. Immunol. 167, 4017-4025
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Interleukin 8 and Its Receptors in Human Colon Carcinoma Cells with Different Metastatic Potentials.

A. Li, M. L. Varney, and R. K. Singh (2001)
Clin. Cancer Res. 7, 3298-3304
 |  Abstract »  |  Full Text »  |  PDF »

99mTc-Interleukin-8 for Imaging Acute Osteomyelitis.

S. Gratz, H. J.J.M. Rennen, O. C. Boerman, W. J.G. Oyen, P. Burma, and F. H.M. Corstens (2001)
J. Nucl. Med. 42, 1257-1264
 |  Abstract »  |  Full Text »  |  PDF »

Antituberculosis Treatment: Increasing Evidence for Drug Effects on Innate Cellular Immunity.

C. T. Tiemessen, S. Shalekoff, S. Meddows-Taylor, and D. J. Martin (2001)
Clin. Vaccine Immunol. 8, 686-689
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Rapid Imaging of Experimental Colitis with 99mTc-Interleukin-8 in Rabbits.

S. Gratz, H. J.J.M. Rennen, O. C. Boerman, W. J.G. Oyen, and F. H.M. Corstens (2001)
J. Nucl. Med. 42, 917-923
 |  Abstract »  |  Full Text »  |  PDF »

Rapid Up-Regulation of CXC Chemokines in the Airways after Ag-Specific CD4+ T Cell Activation.

P. G. Knott, P. R. Gater, P. J. Dunford, M. E. Fuentes, and C. P. Bertrand (2001)
J. Immunol. 166, 1233-1240
 |  Abstract »  |  Full Text »  |  PDF »

Lack of correlation between chemokine receptor and Th1/Th2 cytokine expression by individual memory T cells.

T. Nanki and P. E. Lipsky (2000)
Int. Immunol. 12, 1659-1667
 |  Abstract »  |  Full Text »  |  PDF »

Autocrine regulation of interleukin-8 production in human monocytes.

D. D. Browning, W. C. Diehl, M. H. Hsu, I. U. Schraufstatter, and R. D. Ye (2000)
Am J Physiol Lung Cell Mol Physiol 279, L1129-L1136
 |  Abstract »  |  Full Text »  |  PDF »

Stromal Cell-Derived Factor-1-CXC Chemokine Receptor 4 Interactions Play a Central Role in CD4+ T Cell Accumulation in Rheumatoid Arthritis Synovium.

T. Nanki, K. Hayashida, H. S. El-Gabalawy, S. Suson, K. Shi, H. J. Girschick, S. Yavuz, and P. E. Lipsky (2000)
J. Immunol. 165, 6590-6598
 |  Abstract »  |  Full Text »  |  PDF »

The CXC Chemokine Receptor 2, CXCR2, Is the Putative Receptor for ELR+ CXC Chemokine-Induced Angiogenic Activity.

C. L. Addison, T. O. Daniel, M. D. Burdick, H. Liu, J. E. Ehlert, Y. Y. Xue, L. Buechi, A. Walz, A. Richmond, and R. M. Strieter (2000)
J. Immunol. 165, 5269-5277
 |  Abstract »  |  Full Text »  |  PDF »

Transepithelial Neutrophil Migration Is CXCR1 Dependent In Vitro and Is Defective in IL-8 Receptor Knockout Mice.

G. Godaly, L. Hang, B. Frendeus, and C. Svanborg (2000)
J. Immunol. 165, 5287-5294
 |  Abstract »  |  Full Text »  |  PDF »

A Second Leukotriene B4 Receptor, BLT2: A New Therapeutic Target in Inflammation and Immunological Disorders.

T. Yokomizo, K. Kato, K. Terawaki, T. Izumi, and T. Shimizu (2000)
J. Exp. Med. 192, 421-432
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Identification of Distinct Surface-Expressed and Intracellular CXC-Chemokine Receptor 2 Glycoforms in Neutrophils: N-Glycosylation Is Essential for Maintenance of Receptor Surface Expression.

A. Ludwig, J. E. Ehlert, H.-D. Flad, and E. Brandt (2000)
J. Immunol. 165, 1044-1052
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Disease-Progression Genes in Human Gastric Carcinoma Cells by Interleukin 8.

Y. Kitadai, K. Haruma, N. Mukaida, Y. Ohmoto, N. Matsutani, W. Yasui, S. Yamamoto, K. Sumii, G. Kajiyama, I. J. Fidler, et al. (2000)
Clin. Cancer Res. 6, 2735-2740
 |  Abstract »  |  Full Text »

Chemokine receptors and their role in inflammation and infectious diseases.

C. Murdoch and A. Finn (2000)
Blood 95, 3032-3043
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin 8 Expression Regulates Tumorigenicity and Metastases in Androgen-independent Prostate Cancer.

K. Inoue, J. W. Slaton, B. Y. Eve, S. J. Kim, P. Perrotte, M. D. Balbay, S. Yano, M. Bar-Eli, R. Radinsky, C. A. Pettaway, et al. (2000)
Clin. Cancer Res. 6, 2104-2119
 |  Abstract »  |  Full Text »

Reactive Nitrogen and Oxygen Species Attenuate Interleukin- 8-induced Neutrophil Chemotactic Activity in Vitro.

E. Sato, K. L. Simpson, M. B. Grisham, S. Koyama, and R. A. Robbins (2000)
J. Biol. Chem. 275, 10826-10830
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin 8 Expression Regulates Tumorigenicity and Metastasis in Human Bladder Cancer.

K. Inoue, J. W. Slaton, S. J. Kim, P. Perrotte, B. Y. Eve, M. Bar-Eli, R. Radinsky, and C. P. N. Dinney (2000)
Cancer Res. 60, 2290-2299
 |  Abstract »  |  Full Text »

Polarization and interaction of adhesion molecules P-selectin glycoprotein ligand 1 and intercellular adhesion molecule 3 with moesin and ezrin in myeloid cells.

J. L. Alonso-Lebrero, J. M. Serrador, C. Dominguez-Jimenez, O. Barreiro, A. Luque, M. A. del Pozo, K. Snapp, G. Kansas, R. Schwartz-Albiez, H. Furthmayr, et al. (2000)
Blood 95, 2413-2419
 |  Abstract »  |  Full Text »  |  PDF »

International Union of Pharmacology. XXII. Nomenclature for Chemokine Receptors.

P. M. Murphy, M. Baggiolini, I. F. Charo, C. A. Hebert, R. Horuk, K. Matsushima, L. H. Miller, J. J. Oppenheim, and C. A. Power (2000)
Pharmacol. Rev. 52, 145-176
 |  Abstract »  |  Full Text »  |  PDF »

GCP-2-induced internalization of IL-8 receptors: hierarchical relationships between GCP-2 and other ELR+-CXC chemokines and mechanisms regulating CXCR2 internalization and recycling.

R. Feniger-Barish, D. Belkin, A. Zaslaver, S. Gal, M. Dori, M. Ran, and A. Ben-Baruch (2000)
Blood 95, 1551-1559
 |  Abstract »  |  Full Text »  |  PDF »

NH2- and COOH-Terminal Truncations of Murine Granulocyte Chemotactic Protein-2 Augment the In Vitro and In Vivo Neutrophil Chemotactic Potency.

A. Wuyts, A. D'Haese, V. Cremers, P. Menten, J.-P. Lenaerts, A. De Loof, H. Heremans, P. Proost, and J. Van Damme (1999)
J. Immunol. 163, 6155-6163
 |  Abstract »  |  Full Text »  |  PDF »

Physiological Regulation of G Protein-Linked Signaling.

A. J. Morris and C. C. Malbon (1999)
Physiol Rev 79, 1373-1430
 |  Abstract »  |  Full Text »  |  PDF »

Chemokine Amplification in Mesangial Cells.

Y. Luo, C. Lloyd, J.-C. Gutierrez-Ramos, and M. E. Dorf (1999)
J. Immunol. 163, 3985-3992
 |  Abstract »  |  Full Text »  |  PDF »

Cytokines in asthma.

K F Chung and P J Barnes (1999)
Thorax 54, 825-857
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NF-{kappa}B Activation Is Required for C5a-Induced Interleukin-8 Gene Expression in Mononuclear Cells.

M. H. Hsu, M. Wang, D. D. Browning, N. Mukaida, and R. D. Ye (1999)
Blood 93, 3241-3249
 |  Abstract »  |  Full Text »  |  PDF »

Mast Cell Migratory Response to Interleukin-8 Is Mediated Through Interaction With Chemokine Receptor CXCR2/Interleukin-8RB.

G. Nilsson, J. A. Mikovits, D. D. Metcalfe, and D. D. Taub (1999)
Blood 93, 2791-2797
 |  Abstract »  |  Full Text »  |  PDF »

Differential Mechanisms of Recognition and Activation of Interleukin-8 Receptor Subtypes.

K. Suetomi, Z. Lu, T. Heck, T. G. Wood, D. J. Prusak, K. J. Dunn, and J. Navarro (1999)
J. Biol. Chem. 274, 11768-11772
 |  Abstract »  |  Full Text »  |  PDF »

Role of Clathrin-mediated Endocytosis in CXCR2 Sequestration, Resensitization, and Signal Transduction.

W. Yang, D. Wang, and A. Richmond (1999)
J. Biol. Chem. 274, 11328-11333
 |  Abstract »  |  Full Text »  |  PDF »

Expression and Function of the Chemokine Receptors CXCR1 and CXCR2 in Sepsis.

C. J. Cummings, T. R. Martin, C. W. Frevert, J. M. Quan, V. A. Wong, S. M. Mongovin, T. R. Hagen, K. P. Steinberg, and R. B. Goodman (1999)
J. Immunol. 162, 2341-2346
 |  Abstract »  |  Full Text »  |  PDF »

Selective Expression of a Novel Surface Molecule by Human Th2 Cells In Vivo.

K. Nagata, K. Tanaka, K. Ogawa, K. Kemmotsu, T. Imai, O. Yoshie, H. Abe, K. Tada, M. Nakamura, K. Sugamura, et al. (1999)
J. Immunol. 162, 1278-1286
 |  Abstract »  |  Full Text »  |  PDF »

The Biologic Role of Interleukin-8: Functional Analysis and Expression of CXCR1 and CXCR2 on Human Eosinophils.

H. Petering, O. Gotze, D. Kimmig, R. Smolarski, A. Kapp, and J. Elsner (1999)
Blood 93, 694-702
 |  Abstract »  |  Full Text »  |  PDF »

Inflammatory Mediators of Asthma: An Update.

P. J. Barnes, K. F. Chung, and C. P. Page (1998)
Pharmacol. Rev. 50, 515-596
 |  Abstract »  |  Full Text »  |  PDF »

A His19 to Ala Mutant of Melanoma Growth-Stimulating Activity Is a Partial Antagonist of the CXCR2 Receptor.

D. L. Baly, R. Horuk, D. G. Yansura, L. C. Simmons, W. J. Fairbrother, C. Kotts, C. M. Wirth, B. L. Gillece-Castro, K. Toy, J. Hesselgesser, et al. (1998)
J. Immunol. 161, 4944-4949
 |  Abstract »  |  Full Text »  |  PDF »

A Chondroitin Sulfate Proteoglycan on Human Neutrophils Specifically Binds Platelet Factor 4 and Is Involved in Cell Activation.

F. Petersen, L. Bock, H.-D. Flad, and E. Brandt (1998)
J. Immunol. 161, 4347-4355
 |  Abstract »  |  Full Text »  |  PDF »

Differential Cross-regulation of the Human Chemokine Receptors CXCR1 and CXCR2. EVIDENCE FOR TIME-DEPENDENT SIGNAL GENERATION.

R. M. Richardson, B. C. Pridgen, B. Haribabu, H. Ali, and R. Snyderman (1998)
J. Biol. Chem. 273, 23830-23836
 |  Abstract »  |  Full Text »  |  PDF »

Binding and Functional Properties of Recombinant and Endogenous CXCR3 Chemokine Receptors.

Y. Weng, S. J. Siciliano, K. E. Waldburger, A. Sirotina-Meisher, M. J. Staruch, B. L. Daugherty, S. L. Gould, M. S. Springer, and J. A. DeMartino (1998)
J. Biol. Chem. 273, 18288-18291
 |  Abstract »  |  Full Text »  |  PDF »

Human Herpesvirus 6 Open Reading Frame U12 Encodes a Functional beta -Chemokine Receptor.

Y. Isegawa, Z. Ping, K. Nakano, N. Sugimoto, and K. Yamanishi (1998)
J. Virol. 72, 6104-6112
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-inducible T Cell Alpha Chemoattractant (I-TAC): A Novel Non-ELR CXC Chemokine with Potent Activity on Activated T Cells through Selective High Affinity Binding to CXCR3.

K. E. Cole, C. A. Strick, T. J. Paradis, K. T. Ogborne, M. Loetscher, R. P. Gladue, W. Lin, J. G. Boyd, B. Moser, D. E. Wood, et al. (1998)
J. Exp. Med. 187, 2009-2021
 |  Abstract »  |  Full Text »  |  PDF »

Down-Regulation of CXCR2 Expression on Human Polymorphonuclear Leukocytes by TNF-{alpha}.

K. Asagoe, K. Yamamoto, A. Takahashi, K. Suzuki, A. Maeda, M. Nohgawa, N. Harakawa, K. Takano, N. Mukaida, K. Matsushima, et al. (1998)
J. Immunol. 160, 4518-4525
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Potent, Selective Non-peptide CXCR2 Antagonist That Inhibits Interleukin-8-induced Neutrophil Migration.

J. R. White, J. M. Lee, P. R. Young, R. P. Hertzberg, A. J. Jurewicz, M. A. Chaikin, K. Widdowson, J. J. Foley, L. D. Martin, D. E. Griswold, et al. (1998)
J. Biol. Chem. 273, 10095-10098
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Signaling Pathways of Human Interleukin-8 Receptor A. INDEPENDENT REGULATION BY PHOSPHORYLATION.

R. M. Richardson, H. Ali, B. C. Pridgen, B. Haribabu, and R. Snyderman (1998)
J. Biol. Chem. 273, 10690-10695
 |  Abstract »  |  Full Text »  |  PDF »

Secondary Lymphoid-tissue Chemokine Is a Functional Ligand for the CC Chemokine Receptor CCR7.

R. Yoshida, M. Nagira, M. Kitaura, N. Imagawa, T. Imai, and O. Yoshie (1998)
J. Biol. Chem. 273, 7118-7122
 |  Abstract »  |  Full Text »  |  PDF »

Superinduction of IL-8 in T Cells by HIV-1 Tat Protein Is Mediated Through NF-{kappa}B Factors.

M. Ott, J. L. Lovett, L. Mueller, and E. Verdin (1998)
J. Immunol. 160, 2872-2880
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Constitutive Signaling of Kaposi's Sarcoma-associated Herpesvirus G Protein-Coupled Receptor by Protein Kinases in Mammalian Cells in Culture.

E. Geras-Raaka, L. Arvanitakis, C. Bais, E. Cesarman, E. A. Mesri, and M. C. Gershengorn (1998)
J. Exp. Med. 187, 801-806
 |  Abstract »  |  Full Text »  |  PDF »

Human Vascular Smooth Muscle Cells Express Receptors for CC Chemokines.

I. M. Hayes, N. J. Jordan, S. Towers, G. Smith, J. R. Paterson, J. J. Earnshaw, A. G. Roach, J. Westwick, and R. J. Williams (1998)
Arterioscler. Thromb. Vasc. Biol. 18, 397-403
 |  Abstract »  |  Full Text »  |  PDF »

Identification of CCR8 as the Specific Receptor for the Human {beta}-Chemokine I-309: Cloning and Molecular Characterization of Murine CCR8 as the Receptor for TCA-3.

I. Goya, J. Gutierrez, R. Varona, L. Kremer, A. Zaballos, and G. Marquez (1998)
J. Immunol. 160, 1975-1981
 |  Abstract »  |  Full Text »  |  PDF »

CXC Chemokines Suppress Proliferation of Myeloid Progenitor Cells by Activation of the CXC Chemokine Receptor 2.

X. Sanchez, K. Suetomi, B. Cousins-Hodges, J. K. Horton, and J. Navarro (1998)
J. Immunol. 160, 906-910
 |  Abstract »  |  Full Text »  |  PDF »

Cloning and Characterization of a Novel Promiscuous Human beta -Chemokine Receptor D6.

R. J. B. Nibbs, S. M. Wylie, J. Yang, N. R. Landau, and G. J. Graham (1997)
J. Biol. Chem. 272, 32078-32083
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Five-Transmembrane Hematopoietic Stem Cell Antigen: Isolation, Characterization, and Molecular Cloning.

S. Miraglia, W. Godfrey, A. H. Yin, K. Atkins, R. Warnke, J. T. Holden, R. A. Bray, E. K. Waller, and D. W. Buck (1997)
Blood 90, 5013-5021
 |  Abstract »  |  Full Text »  |  PDF »

The CXC-Chemokine Neutrophil-Activating Peptide-2 Induces Two Distinct Optima of Neutrophil Chemotaxis by Differential Interaction With Interleukin-8 Receptors CXCR-1 and CXCR-2.

A. Ludwig, F. Petersen, S. Zahn, O. Gotze, J.-M. Schroder, H.-D. Flad, and E. Brandt (1997)
Blood 90, 4588-4597
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of regulator of G protein signaling function by two mutant RGS4 proteins.

K. M. Druey and J. H. Kehrl (1997)
PNAS 94, 12851-12856
 |  Abstract »  |  Full Text »  |  PDF »

Upregulation of Interleukin 8 by Oxygen-deprived Cells in Glioblastoma Suggests a Role in Leukocyte Activation, Chemotaxis, and Angiogenesis.

I. Desbaillets, A.-C. Diserens, N. d. Tribolet, M.-F. Hamou, and E. G.  V. Meir (1997)
J. Exp. Med. 186, 1201-1212
 |  Abstract »  |  Full Text »  |  PDF »

The alpha  Chemokine, Interleukin 8, Inhibits the Antiviral Action of Interferon alpha  .

K. S.A. Khabar, F. Al-Zoghaibi, M. N. Al-Ahdal, T. Murayama, M. Dhalla, N. Mukaida, M. Taha, S. T. Al-Sedairy, Y. Siddiqui, G. Kessie, et al. (1997)
J. Exp. Med. 186, 1077-1085
 |  Abstract »  |  Full Text »  |  PDF »

Cloning and Characterization of a Specific Receptor for the Novel CC Chemokine MIP-3alpha from Lung Dendritic Cells.

C. A. Power, D. J. Church, A. Meyer, S. Alouani, A. E.I. Proudfoot, I. Clark-Lewis, S. Sozzani, A. Mantovani, and T. N.C. Wells (1997)
J. Exp. Med. 186, 825-835
 |  Abstract »  |  Full Text »  |  PDF »

Two Orphan Seven-Transmembrane Segment Receptors Which Are Expressed in CD4-positive Cells Support Simian Immunodeficiency Virus Infection.

M. Farzan, H. Choe, K. Martin, L. Marcon, W. Hofmann, G. Karlsson, Y. Sun, P. Barrett, N. Marchand, N. Sullivan, et al. (1997)
J. Exp. Med. 186, 405-411
 |  Abstract »  |  Full Text »  |  PDF »

Chemokines.

B. J. Rollins (1997)
Blood 90, 909-928
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Chemokine Antagonists That Discriminate between Interleukin-8 Receptors. SELECTIVE BLOCKERS OF CXCR2.

S. A. Jones, B. Dewald, I. Clark-Lewis, and M. Baggiolini (1997)
J. Biol. Chem. 272, 16166-16169
 |  Abstract »  |  Full Text »  |  PDF »

Cloning, in Vitro Expression, and Functional Characterization of a Novel Human CC Chemokine of the Monocyte Chemotactic Protein (MCP) Family (MCP-4) That Binds and Signals through the CC Chemokine Receptor 2B.

T. A. Berkhout, H. M. Sarau, K. Moores, J. R White, N. Elshourbagy, E. Appelbaum, J. Makwana, J. J. Foley, D. B Schmidt, C. Imburgia, et al. (1997)
J. Biol. Chem. 272, 16404-16413
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Cloning and Characterization of a cDNA, CHEMR1, Encoding a Chemokine Receptor With a Homology to the Human C-C Chemokine Receptor, CCR-4.

B.-S. Youn, S.-H. Kim, M. S. Lyu, C. A. Kozak, D. D. Taub, and B. S. Kwon (1997)
Blood 89, 4448-4460
 |  Abstract »  |  Full Text »  |  PDF »

Identification of CCR6, the Specific Receptor for a Novel Lymphocyte-directed CC Chemokine LARC.

M. Baba, T. Imai, M. Nishimura, M. Kakizaki, S. Takagi, K. Hieshima, H. Nomiyama, and O. Yoshie (1997)
J. Biol. Chem. 272, 14893-14898
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Cloning of a Novel Human CC Chemokine EBI1-ligand Chemokine That Is a Specific Functional Ligand for EBI1, CCR7.

R. Yoshida, T. Imai, K. Hieshima, J. Kusuda, M. Baba, M. Kitaura, M. Nishimura, M. Kakizaki, H. Nomiyama, and O. Yoshie (1997)
J. Biol. Chem. 272, 13803-13809
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Two Rat Genes Orthologous to the Human Interleukin-8 Receptors.

C.-A. N. Dunstan, M. N. Salafranca, S. Adhikari, Y. Xia, L. Feng, and J. K. Harrison (1996)
J. Biol. Chem. 271, 32770-32776
 |  Abstract »  |  Full Text »  |  PDF »

Discrete Steps in Binding and Signaling of Interleukin-8 with Its Receptor.

L. Wu, N. Ruffing, X. Shi, W. Newman, D. Soler, C. R. Mackay, and S. Qin (1996)
J. Biol. Chem. 271, 31202-31209
 |  Abstract »  |  Full Text »  |  PDF »

The N Terminus of Bradykinin When Bound to the Human Bradykinin B2 Receptor Is Adjacent to Extracellular Cys20 and Cys277 in the Receptor.

M. C.S. Herzig, N. R. Nash, M. Connolly, D. J. Kyle, and L. M.F. Leeb-Lundberg (1996)
J. Biol. Chem. 271, 29746-29751
 |  Abstract »  |  Full Text »  |  PDF »

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