Science 13 September 1991: Vol. 253. no. 5025, pp. 1278 - 1280 DOI: 10.1126/science.1840701

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Articles

Interleukin 8 and cardiovascular disease.

S. Apostolakis, K. Vogiatzi, V. Amanatidou, and D. A. Spandidos (2009)
Cardiovasc Res 84, 353-360
 |  Abstract »  |  Full Text »  |  PDF »

CXC Receptor-1 Silencing Inhibits Androgen-Independent Prostate Cancer.

N. Shamaladevi, D. A. Lyn, D. O. Escudero, and B. L. Lokeshwar (2009)
Cancer Res. 69, 8265-8274
 |  Abstract »  |  Full Text »  |  PDF »

CXCR2 Inverse Agonism Detected by Arrestin Redistribution.

S. Kredel, M. Wolff, J. Wiedenmann, B. Moepps, G. U. Nienhaus, P. Gierschik, B. Kistler, and R. Heilker (2009)
J Biomol Screen 14, 1076-1091
 |  Abstract »  |  PDF »

The functional significance behind expressing two IL-8 receptor types on PMN.

R. Stillie, S. M. Farooq, J. R. Gordon, and A. W. Stadnyk (2009)
J. Leukoc. Biol. 86, 529-543
 |  Abstract »  |  Full Text »  |  PDF »

Where the Confusion Began: Cloning the First Chemokine Receptors.

B. J. Rollins (2009)
J. Immunol. 183, 2893-2894
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Cytokine Gene Expression After Total Hip Arthroplasty: Surgical Site versus Circulating Neutrophil Response.

A. Buvanendran, K. Mitchell, J. S. Kroin, and M. J. Iadarola (2009)
Anesth. Analg. 109, 959-964
 |  Abstract »  |  Full Text »  |  PDF »

IL-8 signaling does not mediate intra-amniotic LPS-induced inflammation and maturation in preterm fetal lamb lung.

S. G. Kallapur, T. J. M. Moss, R. L. Auten Jr., I. Nitsos, J. J. Pillow, B. W. Kramer, D. Y. Maeda, J. P. Newnham, M. Ikegami, and A. H. Jobe (2009)
Am J Physiol Lung Cell Mol Physiol 297, L512-L519
 |  Abstract »  |  Full Text »  |  PDF »

Kynurenic Acid Triggers Firm Arrest of Leukocytes to Vascular Endothelium under Flow Conditions.

M. C. Barth, N. Ahluwalia, T. J. T. Anderson, G. J. Hardy, S. Sinha, J. A. Alvarez-Cardona, I. E. Pruitt, E. P. Rhee, R. A. Colvin, and R. E. Gerszten (2009)
J. Biol. Chem. 284, 19189-19195
 |  Abstract »  |  Full Text »  |  PDF »

Estradiol Increases IL-8 Secretion of Normal Human Breast Tissue and Breast Cancer In Vivo.

C. Bendrik and C. Dabrosin (2009)
J. Immunol. 182, 371-378
 |  Abstract »  |  Full Text »  |  PDF »

The Interleukin-8 Pathway in Cancer.

D. J.J. Waugh and C. Wilson (2008)
Clin. Cancer Res. 14, 6735-6741
 |  Abstract »  |  Full Text »  |  PDF »

Citrullination of CXCL8 by peptidylarginine deiminase alters receptor usage, prevents proteolysis, and dampens tissue inflammation.

P. Proost, T. Loos, A. Mortier, E. Schutyser, M. Gouwy, S. Noppen, C. Dillen, I. Ronsse, R. Conings, S. Struyf, et al. (2008)
J. Exp. Med. 205, 2085-2097
 |  Abstract »  |  Full Text »  |  PDF »

Re-evaluation of Chicken CXCR1 Determines the True Gene Structure: CXCLi1 (K60) AND CXCLi2 (CAF/INTERLEUKIN-8) ARE LIGANDS FOR THIS RECEPTOR.

T. Y. Poh, J. Pease, J. R. Young, N. Bumstead, and P. Kaiser (2008)
J. Biol. Chem. 283, 16408-16415
 |  Abstract »  |  Full Text »  |  PDF »

Abnormal in vitro CXCR2 modulation and defective cationic ion transporter expression on polymorphonuclear neutrophils responsible for hyporesponsiveness to IL-8 stimulation in patients with active systemic lupus erythematosus.

S.-C. Hsieh, T.-H. Wu, C.-Y. Tsai, K.-J. Li, M.-C. Lu, C.-H. Wu, and C.-L. Yu (2008)
Rheumatology 47, 150-157
 |  Abstract »  |  Full Text »  |  PDF »

Transactivation of Vascular Endothelial Growth Factor Receptor-2 by Interleukin-8 (IL-8/CXCL8) Is Required for IL-8/CXCL8-induced Endothelial Permeability.

M. L. Petreaca, M. Yao, Y. Liu, K. DeFea, and M. Martins-Green (2007)
Mol. Biol. Cell 18, 5014-5023
 |  Abstract »  |  Full Text »  |  PDF »

Mouse Neutrophils Require JNK2 MAPK for Toxoplasma gondii-Induced IL-12p40 and CCL2/MCP-1 Release.

W. Sukhumavasi, C. E. Egan, and E. Y. Denkers (2007)
J. Immunol. 179, 3570-3577
 |  Abstract »  |  Full Text »  |  PDF »

Murine CXCR1 Is a Functional Receptor for GCP-2/CXCL6 and Interleukin-8/CXCL8.

X. Fan, A. C. Patera, A. Pong-Kennedy, G. Deno, W. Gonsiorek, D. J. Manfra, G. Vassileva, M. Zeng, C. Jackson, L. Sullivan, et al. (2007)
J. Biol. Chem. 282, 11658-11666
 |  Abstract »  |  Full Text »  |  PDF »

CXCR1 and CXCR2 Activation and Regulation: ROLE OF ASPARTATE 199 OF THE SECOND EXTRACELLULAR LOOP OF CXCR2 IN CXCL8-MEDIATED RAPID RECEPTOR INTERNALIZATION.

M. W. Nasser, S. K. Raghuwanshi, K. M. Malloy, P. Gangavarapu, J.-Y. Shim, K. Rajarathnam, and R. M. Richardson (2007)
J. Biol. Chem. 282, 6906-6915
 |  Abstract »  |  Full Text »  |  PDF »

99mTc-Labeled Interleukin 8 for the Scintigraphic Detection of Infection and Inflammation: First Clinical Evaluation.

C. P. Bleeker-Rovers, H. J.J.M. Rennen, O. C. Boerman, A. B. Wymenga, E. P. Visser, J. H. Bakker, J. W.M. van der Meer, F. H.M. Corstens, and W. J.G. Oyen (2007)
J. Nucl. Med. 48, 337-343
 |  Abstract »  |  Full Text »  |  PDF »

Muscle: Exercise induces interleukin-8 receptor (CXCR2) expression in human skeletal muscle.

L. Frydelund-Larsen, M. Penkowa, T. Akerstrom, A. Zankari, S. Nielsen, and B. K. Pedersen (2007)
Exp Physiol 92, 233-240
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-8: novel roles in human airway smooth muscle cell contraction and migration.

V. Govindaraju, M.-C. Michoud, M. Al-Chalabi, P. Ferraro, W. S. Powell, and J. G. Martin (2006)
Am J Physiol Cell Physiol 291, C957-C965
 |  Abstract »  |  Full Text »  |  PDF »

Associations of Classic Kaposi Sarcoma with Common Variants in Genes that Modulate Host Immunity..

E. E. Brown, D. Fallin, I. Ruczinski, A. Hutchinson, B. Staats, F. Vitale, C. Lauria, D. Serraino, G. Rezza, G. Mbisa, et al. (2006)
Cancer Epidemiol. Biomarkers Prev. 15, 926-934
 |  Abstract »  |  Full Text »  |  PDF »

Neutrophil chemorepulsion in defined interleukin-8 gradients in vitro and in vivo.

W. G. Tharp, R. Yadav, D. Irimia, A. Upadhyaya, A. Samadani, O. Hurtado, S-Y. Liu, S. Munisamy, D. M. Brainard, M. J. Mahon, et al. (2006)
J. Leukoc. Biol. 79, 539-554
 |  Abstract »  |  Full Text »  |  PDF »

Neutrophils Accelerate Macrophage-Mediated Digestion of Apoptotic Cells In Vivo as Well as In Vitro.

T. Iyoda, K. Nagata, M. Akashi, and Y. Kobayashi (2005)
J. Immunol. 175, 3475-3483
 |  Abstract »  |  Full Text »  |  PDF »

Impaired Neutrophil Migration Associated with Specific Bovine CXCR2 Genotypes.

M. Rambeaud and G. M. Pighetti (2005)
Infect. Immun. 73, 4955-4959
 |  Abstract »  |  Full Text »  |  PDF »

The Macrophage-derived Lectin, MNCF, Activates Neutrophil Migration through a Pertussis Toxin-sensitive Pathway.

A. N. Moreno, G. Pereira-da-Silva, C. Oliver, M. C. Jamur, A. Panunto-Castelo, and M. C. Roque-Barreira (2005)
J. Histochem. Cytochem. 53, 715-723
 |  Abstract »  |  Full Text »  |  PDF »

Differential Expression of Interleukin-8 and Its Receptors in the Neuroendocrine and Non-Neuroendocrine Compartments of Prostate Cancer.

J. Huang, J. L. Yao, L. Zhang, P. A. Bourne, A. M. Quinn, P. A. di Sant'Agnese, and J. E. Reeder (2005)
Am. J. Pathol. 166, 1807-1815
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The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis.

D. J. Brat, A. C. Bellail, and E. G. Van Meir (2005)
Neuro-oncol 7, 122-133
 |  Abstract »  |  PDF »

Expression of interleukin-8 receptors in endometriosis.

M. Ulukus, E.C. Ulukus, Y. Seval, W. Zheng, and A. Arici (2005)
Hum. Reprod. 20, 794-801
 |  Abstract »  |  Full Text »  |  PDF »

IL-8 and its CXCR1 and CXCR2 receptors participate in the control of megakaryocytic proliferation, differentiation, and ploidy in myeloid metaplasia with myelofibrosis.

S. Emadi, D. Clay, C. Desterke, B. Guerton, E. Maquarre, A. Charpentier, C. Jasmin, M.-C. Le Bousse-Kerdiles, and for the French INSERM Research Network on MMM (2005)
Blood 105, 464-473
 |  Abstract »  |  Full Text »  |  PDF »

Downregulation of CXCR1 and CXCR2 Expression on Human Neutrophils by Helicobacter pylori: a New Pathomechanism in H. pylori Infection?.

B. Schmausser, C. Josenhans, S. Endrich, S. Suerbaum, C. Sitaru, M. Andrulis, S. Brandlein, P. Rieckmann, H. K. Muller-Hermelink, and M. Eck (2004)
Infect. Immun. 72, 6773-6779
 |  Abstract »  |  Full Text »  |  PDF »

99mTc-Labeled Interleukin-8 for Scintigraphic Detection of Pulmonary Infections.

H. J. J. M. Rennen, C. P. Bleeker-Rovers, J. E. M. van Eerd, C. Frielink, W. J. G. Oyen, F. H. M. Corstens, and O. C. Boerman (2004)
Chest 126, 1954-1961
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Association of CXCR2 Polymorphisms with Subclinical and Clinical Mastitis in Dairy Cattle.

S. M. Youngerman, A. M. Saxton, S. P. Oliver, and G. M. Pighetti (2004)
J Dairy Sci 87, 2442-2448
 |  Abstract »  |  Full Text »  |  PDF »

On the Mechanism and Significance of Ligand-induced Internalization of Human Neutrophil Chemokine Receptors CXCR1 and CXCR2.

J. J. Rose, J. F. Foley, P. M. Murphy, and S. Venkatesan (2004)
J. Biol. Chem. 279, 24372-24386
 |  Abstract »  |  Full Text »  |  PDF »

IL-15 and IL-2 oppositely regulate expression of the chemokine receptor CX3CR1.

J. Barlic, J. M. Sechler, and P. M. Murphy (2003)
Blood 102, 3494-3503
 |  Abstract »  |  Full Text »  |  PDF »

Plasma levels of interleukin-8 and expression of interleukin-8 receptors on circulating neutrophils and monocytes after cardiopulmonary bypass in children.

P. Gessler, J. Pfenninger, J.-P. Pfammatter, T. Carrel, O. Baenziger, and C. Dahinden (2003)
J. Thorac. Cardiovasc. Surg. 126, 718-725
 |  Abstract »  |  Full Text »  |  PDF »

Kinetics of 99mTc-Labeled Interleukin-8 in Experimental Inflammation and Infection.

H. J.J.M. Rennen, O. C. Boerman, W. J.G. Oyen, and F. H.M. Corstens (2003)
J. Nucl. Med. 44, 1502-1509
 |  Abstract »  |  Full Text »  |  PDF »

G protein-coupled receptors in natural killer cells.

A. A. Maghazachi (2003)
J. Leukoc. Biol. 74, 16-24
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Helicobacter pylori Infection Induces Interleukin-8 Receptor Expression in the Human Gastric Epithelium.

F. Backhed, E. Torstensson, D. Seguin, A. Richter-Dahlfors, and B. Rokbi (2003)
Infect. Immun. 71, 3357-3360
 |  Abstract »  |  Full Text »  |  PDF »

Chemokine Receptor Expression in Human Endometrium.

N. Mulayim, S. F. Palter, U. A. Kayisli, L. Senturk, and A. Arici (2003)
Biol Reprod 68, 1491-1495
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Pathophysiological roles of interleukin-8/CXCL8 in pulmonary diseases.

N. Mukaida (2003)
Am J Physiol Lung Cell Mol Physiol 284, L566-L577
 |  Abstract »  |  Full Text »  |  PDF »

A duodenally absorbable CXC chemokine receptor 4 antagonist, KRH-1636, exhibits a potent and selective anti-HIV-1 activity.

K. Ichiyama, S. Yokoyama-Kumakura, Y. Tanaka, R. Tanaka, K. Hirose, K. Bannai, T. Edamatsu, M. Yanaka, Y. Niitani, N. Miyano-Kurosaki, et al. (2003)
PNAS 100, 4185-4190
 |  Abstract »  |  Full Text »  |  PDF »

Role of the Cytoplasmic Tails of CXCR1 and CXCR2 in Mediating Leukocyte Migration, Activation, and Regulation.

R. M. Richardson, R. J. Marjoram, L. S. Barak, and R. Snyderman (2003)
J. Immunol. 170, 2904-2911
 |  Abstract »  |  Full Text »  |  PDF »

IL-8 Directly Enhanced Endothelial Cell Survival, Proliferation, and Matrix Metalloproteinases Production and Regulated Angiogenesis.

A. Li, S. Dubey, M. L. Varney, B. J. Dave, and R. K. Singh (2003)
J. Immunol. 170, 3369-3376
 |  Abstract »  |  Full Text »  |  PDF »

A Potent and Selective Nonpeptide Antagonist of CXCR2 Inhibits Acute and Chronic Models of Arthritis in the Rabbit.

P. L. Podolin, B. J. Bolognese, J. J. Foley, D. B. Schmidt, P. T. Buckley, K. L. Widdowson, Q. Jin, J. R. White, J. M. Lee, R. B. Goodman, et al. (2002)
J. Immunol. 169, 6435-6444
 |  Abstract »  |  Full Text »  |  PDF »

Morphine Regulates Gene Expression of {alpha}- and {beta}-Chemokines and Their Receptors on Astroglial Cells Via the Opioid {micro} Receptor.

S. D. Mahajan, S. A. Schwartz, T. C. Shanahan, R. P. Chawda, and M. P. N. Nair (2002)
J. Immunol. 169, 3589-3599
 |  Abstract »  |  Full Text »  |  PDF »

Signaling Pathways Involved in IL-8-Dependent Activation of Adhesion Through Mac-1.

M. Takami, V. Terry, and L. Petruzzelli (2002)
J. Immunol. 168, 4559-4566
 |  Abstract »  |  Full Text »  |  PDF »

CXCR2 Deficiency Confers Impaired Neutrophil Recruitment and Increased Susceptibility During Toxoplasma gondii Infection.

L. Del Rio, S. Bennouna, J. Salinas, and E. Y. Denkers (2001)
J. Immunol. 167, 6503-6509
 |  Abstract »  |  Full Text »  |  PDF »

Immobilized IL-8 Triggers Progressive Activation of Neutrophils Rolling In Vitro on P-Selectin and Intercellular Adhesion Molecule-1.

J. A. DiVietro, M. J. Smith, B. R. E. Smith, L. Petruzzelli, R. S. Larson, and M. B. Lawrence (2001)
J. Immunol. 167, 4017-4025
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Interleukin 8 and Its Receptors in Human Colon Carcinoma Cells with Different Metastatic Potentials.

A. Li, M. L. Varney, and R. K. Singh (2001)
Clin. Cancer Res. 7, 3298-3304
 |  Abstract »  |  Full Text »  |  PDF »

CD18 Dependency of Transendothelial Neutrophil Migration Differs During Acute Pulmonary Inflammation.

A. J. Mackarel, K. J. Russell, C. M. Ryan, S. J. Hislip, J. C. Rendall, M. X. FitzGerald, and C. M. O'Connor (2001)
J. Immunol. 167, 2839-2846
 |  Abstract »  |  Full Text »  |  PDF »

99mTc-Interleukin-8 for Imaging Acute Osteomyelitis.

S. Gratz, H. J.J.M. Rennen, O. C. Boerman, W. J.G. Oyen, P. Burma, and F. H.M. Corstens (2001)
J. Nucl. Med. 42, 1257-1264
 |  Abstract »  |  Full Text »  |  PDF »

Antituberculosis Treatment: Increasing Evidence for Drug Effects on Innate Cellular Immunity.

C. T. Tiemessen, S. Shalekoff, S. Meddows-Taylor, and D. J. Martin (2001)
Clin. Vaccine Immunol. 8, 686-689
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Rapid Imaging of Experimental Colitis with 99mTc-Interleukin-8 in Rabbits.

S. Gratz, H. J.J.M. Rennen, O. C. Boerman, W. J.G. Oyen, and F. H.M. Corstens (2001)
J. Nucl. Med. 42, 917-923
 |  Abstract »  |  Full Text »  |  PDF »

Cell-surface heparan sulfate proteoglycan-mediated regulation of human neutrophil migration by the serpin antithrombin III.

S. Dunzendorfer, N. Kaneider, A. Rabensteiner, C. Meierhofer, C. Reinisch, J. Romisch, and C. J. Wiedermann (2001)
Blood 97, 1079-1085
 |  Abstract »  |  Full Text »  |  PDF »

Rapid Up-Regulation of CXC Chemokines in the Airways after Ag-Specific CD4+ T Cell Activation.

P. G. Knott, P. R. Gater, P. J. Dunford, M. E. Fuentes, and C. P. Bertrand (2001)
J. Immunol. 166, 1233-1240
 |  Abstract »  |  Full Text »  |  PDF »

Defective Neutrophil Degranulation Induced by Interleukin-8 and Complement 5a and Down-Regulation of Associated Receptors in Children Vertically Infected with Human Immunodeficiency Virus Type 1.

S. Meddows-Taylor, L. Kuhn, T. M. Meyers, G. Sherman, and C. T. Tiemessen (2001)
Clin. Vaccine Immunol. 8, 21-30
 |  Abstract »  |  Full Text »  |  PDF »

Lack of correlation between chemokine receptor and Th1/Th2 cytokine expression by individual memory T cells.

T. Nanki and P. E. Lipsky (2000)
Int. Immunol. 12, 1659-1667
 |  Abstract »  |  Full Text »  |  PDF »

Autocrine regulation of interleukin-8 production in human monocytes.

D. D. Browning, W. C. Diehl, M. H. Hsu, I. U. Schraufstatter, and R. D. Ye (2000)
Am J Physiol Lung Cell Mol Physiol 279, L1129-L1136
 |  Abstract »  |  Full Text »  |  PDF »

Stromal Cell-Derived Factor-1-CXC Chemokine Receptor 4 Interactions Play a Central Role in CD4+ T Cell Accumulation in Rheumatoid Arthritis Synovium.

T. Nanki, K. Hayashida, H. S. El-Gabalawy, S. Suson, K. Shi, H. J. Girschick, S. Yavuz, and P. E. Lipsky (2000)
J. Immunol. 165, 6590-6598
 |  Abstract »  |  Full Text »  |  PDF »

Transepithelial Neutrophil Migration Is CXCR1 Dependent In Vitro and Is Defective in IL-8 Receptor Knockout Mice.

G. Godaly, L. Hang, B. Frendeus, and C. Svanborg (2000)
J. Immunol. 165, 5287-5294
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Distinct Surface-Expressed and Intracellular CXC-Chemokine Receptor 2 Glycoforms in Neutrophils: N-Glycosylation Is Essential for Maintenance of Receptor Surface Expression.

A. Ludwig, J. E. Ehlert, H.-D. Flad, and E. Brandt (2000)
J. Immunol. 165, 1044-1052
 |  Abstract »  |  Full Text »  |  PDF »

CXC Chemokine Receptor CXCR2 Is Essential for Protective Innate Host Response in Murine Pseudomonas aeruginosa Pneumonia.

W. C. Tsai, R. M. Strieter, B. Mehrad, M. W. Newstead, X. Zeng, and T. J. Standiford (2000)
Infect. Immun. 68, 4289-4296
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Disease-Progression Genes in Human Gastric Carcinoma Cells by Interleukin 8.

Y. Kitadai, K. Haruma, N. Mukaida, Y. Ohmoto, N. Matsutani, W. Yasui, S. Yamamoto, K. Sumii, G. Kajiyama, I. J. Fidler, et al. (2000)
Clin. Cancer Res. 6, 2735-2740
 |  Abstract »  |  Full Text »

Chemokine receptors and their role in inflammation and infectious diseases.

C. Murdoch and A. Finn (2000)
Blood 95, 3032-3043
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin 8 Expression Regulates Tumorigenicity and Metastases in Androgen-independent Prostate Cancer.

K. Inoue, J. W. Slaton, B. Y. Eve, S. J. Kim, P. Perrotte, M. D. Balbay, S. Yano, M. Bar-Eli, R. Radinsky, C. A. Pettaway, et al. (2000)
Clin. Cancer Res. 6, 2104-2119
 |  Abstract »  |  Full Text »  |  PDF »

Reactive Nitrogen and Oxygen Species Attenuate Interleukin- 8-induced Neutrophil Chemotactic Activity in Vitro.

E. Sato, K. L. Simpson, M. B. Grisham, S. Koyama, and R. A. Robbins (2000)
J. Biol. Chem. 275, 10826-10830
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin 8 Expression Regulates Tumorigenicity and Metastasis in Human Bladder Cancer.

K. Inoue, J. W. Slaton, S. J. Kim, P. Perrotte, B. Y. Eve, M. Bar-Eli, R. Radinsky, and C. P. N. Dinney (2000)
Cancer Res. 60, 2290-2299
 |  Abstract »  |  Full Text »

Polarization and interaction of adhesion molecules P-selectin glycoprotein ligand 1 and intercellular adhesion molecule 3 with moesin and ezrin in myeloid cells.

J. L. Alonso-Lebrero, J. M. Serrador, C. Dominguez-Jimenez, O. Barreiro, A. Luque, M. A. del Pozo, K. Snapp, G. Kansas, R. Schwartz-Albiez, H. Furthmayr, et al. (2000)
Blood 95, 2413-2419
 |  Abstract »  |  Full Text »  |  PDF »

International Union of Pharmacology. XXII. Nomenclature for Chemokine Receptors.

P. M. Murphy, M. Baggiolini, I. F. Charo, C. A. Hebert, R. Horuk, K. Matsushima, L. H. Miller, J. J. Oppenheim, and C. A. Power (2000)
Pharmacol. Rev. 52, 145-176
 |  Abstract »  |  Full Text »  |  PDF »

GCP-2-induced internalization of IL-8 receptors: hierarchical relationships between GCP-2 and other ELR+-CXC chemokines and mechanisms regulating CXCR2 internalization and recycling.

R. Feniger-Barish, D. Belkin, A. Zaslaver, S. Gal, M. Dori, M. Ran, and A. Ben-Baruch (2000)
Blood 95, 1551-1559
 |  Abstract »  |  Full Text »  |  PDF »

NH2- and COOH-Terminal Truncations of Murine Granulocyte Chemotactic Protein-2 Augment the In Vitro and In Vivo Neutrophil Chemotactic Potency.

A. Wuyts, A. D'Haese, V. Cremers, P. Menten, J.-P. Lenaerts, A. De Loof, H. Heremans, P. Proost, and J. Van Damme (1999)
J. Immunol. 163, 6155-6163
 |  Abstract »  |  Full Text »  |  PDF »

Physiological Regulation of G Protein-Linked Signaling.

A. J. Morris and C. C. Malbon (1999)
Physiol Rev 79, 1373-1430
 |  Abstract »  |  Full Text »  |  PDF »

Cytokines in asthma.

K F Chung and P J Barnes (1999)
Thorax 54, 825-857
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NF-{kappa}B Activation Is Required for C5a-Induced Interleukin-8 Gene Expression in Mononuclear Cells.

M. H. Hsu, M. Wang, D. D. Browning, N. Mukaida, and R. D. Ye (1999)
Blood 93, 3241-3249
 |  Abstract »  |  Full Text »  |  PDF »

Distinct CXC Chemokines Mediate Tumorigenicity of Prostate Cancer Cells.

B. B. Moore, D. A. Arenberg, K. Stoy, T. Morgan, C. L. Addison, S. B. Morris, M. Glass, C. Wilke, Y. Y. Xue, S. Sitterding, et al. (1999)
Am. J. Pathol. 154, 1503-1512
 |  Abstract »  |  Full Text »  |  PDF »

Mast Cell Migratory Response to Interleukin-8 Is Mediated Through Interaction With Chemokine Receptor CXCR2/Interleukin-8RB.

G. Nilsson, J. A. Mikovits, D. D. Metcalfe, and D. D. Taub (1999)
Blood 93, 2791-2797
 |  Abstract »  |  Full Text »  |  PDF »

Differential Mechanisms of Recognition and Activation of Interleukin-8 Receptor Subtypes.

K. Suetomi, Z. Lu, T. Heck, T. G. Wood, D. J. Prusak, K. J. Dunn, and J. Navarro (1999)
J. Biol. Chem. 274, 11768-11772
 |  Abstract »  |  Full Text »  |  PDF »

Role of Clathrin-mediated Endocytosis in CXCR2 Sequestration, Resensitization, and Signal Transduction.

W. Yang, D. Wang, and A. Richmond (1999)
J. Biol. Chem. 274, 11328-11333
 |  Abstract »  |  Full Text »  |  PDF »

Metalloproteinases Are Involved in Lipopolysaccharide- and Tumor Necrosis Factor-alpha -Mediated Regulation of CXCR1 and CXCR2 Chemokine Receptor Expression.

M. H. Khandaker, G. Mitchell, L. Xu, J. D. Andrews, R. Singh, H. Leung, J. Madrenas, S. S.G. Ferguson, R. D. Feldman, and D. J. Kelvin (1999)
Blood 93, 2173-2185
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Dysregulated Production of Interleukin-8 in Individuals Infected with Human Immunodeficiency Virus Type 1 and Mycobacterium tuberculosis.

S. Meddows-Taylor, D. J. Martin, and C. T. Tiemessen (1999)
Infect. Immun. 67, 1251-1260
 |  Abstract »  |  Full Text »  |  PDF »

Expression and Function of the Chemokine Receptors CXCR1 and CXCR2 in Sepsis.

C. J. Cummings, T. R. Martin, C. W. Frevert, J. M. Quan, V. A. Wong, S. M. Mongovin, T. R. Hagen, K. P. Steinberg, and R. B. Goodman (1999)
J. Immunol. 162, 2341-2346
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The Biologic Role of Interleukin-8: Functional Analysis and Expression of CXCR1 and CXCR2 on Human Eosinophils.

H. Petering, O. Gotze, D. Kimmig, R. Smolarski, A. Kapp, and J. Elsner (1999)
Blood 93, 694-702
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Inflammatory Mediators of Asthma: An Update.

P. J. Barnes, K. F. Chung, and C. P. Page (1998)
Pharmacol. Rev. 50, 515-596
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A His19 to Ala Mutant of Melanoma Growth-Stimulating Activity Is a Partial Antagonist of the CXCR2 Receptor.

D. L. Baly, R. Horuk, D. G. Yansura, L. C. Simmons, W. J. Fairbrother, C. Kotts, C. M. Wirth, B. L. Gillece-Castro, K. Toy, J. Hesselgesser, et al. (1998)
J. Immunol. 161, 4944-4949
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Regulation of Chemotactic and Proadhesive Responses to Chemoattractant Receptors by RGS (Regulator of G-protein Signaling) Family Members.

E. P. Bowman, J. J. Campbell, K. M. Druey, A. Scheschonka, J. H. Kehrl, and E. C. Butcher (1998)
J. Biol. Chem. 273, 28040-28048
 |  Abstract »  |  Full Text »  |  PDF »

A Chondroitin Sulfate Proteoglycan on Human Neutrophils Specifically Binds Platelet Factor 4 and Is Involved in Cell Activation.

F. Petersen, L. Bock, H.-D. Flad, and E. Brandt (1998)
J. Immunol. 161, 4347-4355
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Differential Cross-regulation of the Human Chemokine Receptors CXCR1 and CXCR2. EVIDENCE FOR TIME-DEPENDENT SIGNAL GENERATION.

R. M. Richardson, B. C. Pridgen, B. Haribabu, H. Ali, and R. Snyderman (1998)
J. Biol. Chem. 273, 23830-23836
 |  Abstract »  |  Full Text »  |  PDF »

CXCR1 and CXCR2 Are Rapidly Down-Modulated by Bacterial Endotoxin Through a Unique Agonist-Independent, Tyrosine Kinase-Dependent Mechanism.

M. H. Khandaker, L. Xu, R. Rahimpour, G. Mitchell, M. E. DeVries, J. G. Pickering, S. K. Singhal, R. D. Feldman, and D. J. Kelvin (1998)
J. Immunol. 161, 1930-1938
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Binding and Functional Properties of Recombinant and Endogenous CXCR3 Chemokine Receptors.

Y. Weng, S. J. Siciliano, K. E. Waldburger, A. Sirotina-Meisher, M. J. Staruch, B. L. Daugherty, S. L. Gould, M. S. Springer, and J. A. DeMartino (1998)
J. Biol. Chem. 273, 18288-18291
 |  Abstract »  |  Full Text »  |  PDF »

The CC chemokine 6Ckine binds the CXC chemokine receptor CXCR3.

H. Soto, W. Wang, R. M. Strieter, N. G. Copeland, D. J. Gilbert, N. A. Jenkins, J. Hedrick, and A. Zlotnik (1998)
PNAS 95, 8205-8210
 |  Abstract »  |  Full Text »  |  PDF »

Quantitative comparison of C-X-C chemokines produced by endotoxin-stimulated human alveolar macrophages.

R. B. Goodman, R. M. Strieter, C. W. Frevert, C. J. Cummings, P. Tekamp-Olson, S. L. Kunkel, A. Walz, and T. R. Martin (1998)
Am J Physiol Lung Cell Mol Physiol 275, L87-L95
 |  Abstract »  |  Full Text »  |  PDF »

Differential Regulation of Chemoattractant-Stimulated {beta}2, {beta}3, and {beta}7 Integrin Activity.

C. Sadhu, B. Masinovsky, and D. E. Staunton (1998)
J. Immunol. 160, 5622-5628
 |  Abstract »  |  Full Text »  |  PDF »

Down-Regulation of CXCR2 Expression on Human Polymorphonuclear Leukocytes by TNF-{alpha}.

K. Asagoe, K. Yamamoto, A. Takahashi, K. Suzuki, A. Maeda, M. Nohgawa, N. Harakawa, K. Takano, N. Mukaida, K. Matsushima, et al. (1998)
J. Immunol. 160, 4518-4525
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Potent, Selective Non-peptide CXCR2 Antagonist That Inhibits Interleukin-8-induced Neutrophil Migration.

J. R. White, J. M. Lee, P. R. Young, R. P. Hertzberg, A. J. Jurewicz, M. A. Chaikin, K. Widdowson, J. J. Foley, L. D. Martin, D. E. Griswold, et al. (1998)
J. Biol. Chem. 273, 10095-10098
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Signaling Pathways of Human Interleukin-8 Receptor A. INDEPENDENT REGULATION BY PHOSPHORYLATION.

R. M. Richardson, H. Ali, B. C. Pridgen, B. Haribabu, and R. Snyderman (1998)
J. Biol. Chem. 273, 10690-10695
 |  Abstract »  |  Full Text »  |  PDF »

Secondary Lymphoid-tissue Chemokine Is a Functional Ligand for the CC Chemokine Receptor CCR7.

R. Yoshida, M. Nagira, M. Kitaura, N. Imagawa, T. Imai, and O. Yoshie (1998)
J. Biol. Chem. 273, 7118-7122
 |  Abstract »  |  Full Text »  |  PDF »

Superinduction of IL-8 in T Cells by HIV-1 Tat Protein Is Mediated Through NF-{kappa}B Factors.

M. Ott, J. L. Lovett, L. Mueller, and E. Verdin (1998)
J. Immunol. 160, 2872-2880
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Constitutive Signaling of Kaposi's Sarcoma-associated Herpesvirus G Protein-Coupled Receptor by Protein Kinases in Mammalian Cells in Culture.

E. Geras-Raaka, L. Arvanitakis, C. Bais, E. Cesarman, E. A. Mesri, and M. C. Gershengorn (1998)
J. Exp. Med. 187, 801-806
 |  Abstract »  |  Full Text »  |  PDF »

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