Science 21 June 1991: Vol. 252. no. 5013, pp. 1708 - 1711 DOI: 10.1126/science.2047879

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Articles

p53 Oligomerization Is Essential for Its C-terminal Lysine Acetylation.

Y. Itahana, H. Ke, and Y. Zhang (2009)
J. Biol. Chem. 284, 5158-5164
 |  Abstract »  |  Full Text »  |  PDF »

p53 is localized to a sub-nucleolar compartment after proteasomal inhibition in an energy-dependent manner.

O. Karni-Schmidt, A. Zupnick, M. Castillo, A. Ahmed, T. Matos, P. Bouvet, C. Cordon-Cardo, and C. Prives (2008)
J. Cell Sci. 121, 4098-4105
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of genome-wide p53-binding sites upon stress response.

L. Smeenk, S. J. van Heeringen, M. Koeppel, M. A. van Driel, S. J. J. Bartels, R. C. Akkers, S. Denissov, H. G. Stunnenberg, and M. Lohrum (2008)
Nucleic Acids Res. 36, 3639-3654
 |  Abstract »  |  Full Text »  |  PDF »

p53 RNA interactions: New clues in an old mystery.

K. J.-L. Riley and L. J. Maher III (2007)
RNA 13, 1825-1833
 |  Abstract »  |  Full Text »  |  PDF »

TAp73 Is a Downstream Target of p53 in Controlling the Cellular Defense against Stress.

J. Wang, Y.-X. Liu, M. P. Hande, A. C. Wong, Y. J. Jin, and Y. Yin (2007)
J. Biol. Chem. 282, 29152-29162
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: Quaternary structures of tumor suppressor p53 and a specific p53 DNA complex.

H. Tidow, R. Melero, E. Mylonas, S. M. V. Freund, J. G. Grossmann, J. M. Carazo, D. I. Svergun, M. Valle, and A. R. Fersht (2007)
PNAS 104, 12324-12329
 |  Abstract »  |  Full Text »  |  PDF »

The Notch Regulator MAML1 Interacts with p53 and Functions as a Coactivator.

Y. Zhao, R. B. Katzman, L. M. Delmolino, I. Bhat, Y. Zhang, C. B. Gurumurthy, A. Germaniuk-Kurowska, H. V. Reddi, A. Solomon, M.-S. Zeng, et al. (2007)
J. Biol. Chem. 282, 11969-11981
 |  Abstract »  |  Full Text »  |  PDF »

The nuclear function of p53 is required for PUMA-mediated apoptosis induced by DNA damage.

P. Wang, J. Yu, and L. Zhang (2007)
PNAS 104, 4054-4059
 |  Abstract »  |  Full Text »  |  PDF »

p53 Short Peptide (p53pep164) Regulates Lipopolysaccharide-Induced Tumor Necrosis Factor-{alpha} Factor/Cytokine Expression.

X. Tang, M. Molina, and S. Amar (2007)
Cancer Res. 67, 1308-1316
 |  Abstract »  |  Full Text »  |  PDF »

The Human Orthologue of Drosophila Ecdysoneless Protein Interacts with p53 and Regulates Its Function..

Y. Zhang, C. B. Gurumurthy, J. Kim, I. Bhat, Q. Gao, G. Dimri, S. W. Lee, H. Band, and V. Band (2006)
Cancer Res. 66, 7167-7175
 |  Abstract »  |  Full Text »  |  PDF »

Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional program..

N. P. Gomes, G. Bjerke, B. Llorente, S. A. Szostek, B. M. Emerson, and J. M. Espinosa (2006)
Genes & Dev. 20, 601-612
 |  Abstract »  |  Full Text »  |  PDF »

Chromatin Immunoprecipitation-Based Screen To Identify Functional Genomic Binding Sites for Sequence-Specific Transactivators.

J. M. Hearnes, D. J. Mays, K. L. Schavolt, L. Tang, X. Jiang, and J. A. Pietenpol (2005)
Mol. Cell. Biol. 25, 10148-10158
 |  Abstract »  |  Full Text »  |  PDF »

p53 Regulation and Function in Renal Cell Carcinoma.

H. E. Warburton, M. Brady, N. Vlatkovic, W. M. Linehan, K. Parsons, and M. T. Boyd (2005)
Cancer Res. 65, 6498-6503
 |  Abstract »  |  Full Text »  |  PDF »

Insights into Selective Activation of p53 DNA Binding by c-Abl.

G. Wei, A. G. Li, and X. Liu (2005)
J. Biol. Chem. 280, 12271-12278
 |  Abstract »  |  Full Text »  |  PDF »

Identification and Characterization of the IKK{alpha} Promoter: POSITIVE AND NEGATIVE REGULATION BY ETS-1 AND p53, RESPECTIVELY.

L. Gu, N. Zhu, H. W. Findley, W. G. Woods, and M. Zhou (2004)
J. Biol. Chem. 279, 52141-52149
 |  Abstract »  |  Full Text »  |  PDF »

Hsp90 Regulates the Activity of Wild Type p53 under Physiological and Elevated Temperatures.

L. Muller, A. Schaupp, D. Walerych, H. Wegele, and J. Buchner (2004)
J. Biol. Chem. 279, 48846-48854
 |  Abstract »  |  Full Text »  |  PDF »

NAD+ Modulates p53 DNA Binding Specificity and Function.

K. G. McLure, M. Takagi, and M. B. Kastan (2004)
Mol. Cell. Biol. 24, 9958-9967
 |  Abstract »  |  Full Text »  |  PDF »

Recombination at chromosomal sequences involved in leukaemogenic rearrangements is differentially regulated by p53.

G. S. Boehden, A. Restle, R. Marschalek, C. Stocking, and L. Wiesmuller (2004)
Carcinogenesis 25, 1305-1313
 |  Abstract »  |  Full Text »  |  PDF »

Human RAD9 checkpoint control/proapoptotic protein can activate transcription of p21.

Y. Yin, A. Zhu, Y. J. Jin, Y.-X. Liu, X. Zhang, K. M. Hopkins, and H. B. Lieberman (2004)
PNAS 101, 8864-8869
 |  Abstract »  |  Full Text »  |  PDF »

p53 protein interacts specifically with the meiosis-specific mammalian RecA-like protein DMC1 in meiosis.

T. Habu, N. Wakabayashi, K. Yoshida, K. Yomogida, Y. Nishimune, and T. Morita (2004)
Carcinogenesis 25, 889-893
 |  Abstract »  |  Full Text »  |  PDF »

IFN-alpha prevents the growth of pre-neoplastic lesions and inhibits the development of hepatocellular carcinoma in the rat.

M. Nakaji, Y. Yano, T. Ninomiya, Y. Seo, K. Hamano, S. Yoon, M. Kasuga, T. Teramoto, Y. Hayashi, and H. Yokozaki (2004)
Carcinogenesis 25, 389-397
 |  Abstract »  |  Full Text »  |  PDF »

Requirement of Kruppel-like Factor 4 in Preventing Entry into Mitosis following DNA Damage.

H. S. Yoon and V. W. Yang (2004)
J. Biol. Chem. 279, 5035-5041
 |  Abstract »  |  Full Text »  |  PDF »

Two Functionally Divergent p53-responsive Elements in the Rat Bradykinin B2 Receptor Promoter.

J. Marks, Z. Saifudeen, S. Dipp, and S. S. El-Dahr (2003)
J. Biol. Chem. 278, 34158-34166
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of p53 "Latency" and "Activation" by Fluorescence Correlation Spectroscopy: EVIDENCE FOR DIFFERENT MODES OF HIGH AFFINITY DNA BINDING.

J. Wolcke, M. Reimann, M. Klumpp, T. Gohler, E. Kim, and W. Deppert (2003)
J. Biol. Chem. 278, 32587-32595
 |  Abstract »  |  Full Text »  |  PDF »

Replication of damaged DNA in vitro is blocked by p53.

J. Zhou and C. Prives (2003)
Nucleic Acids Res. 31, 3881-3892
 |  Abstract »  |  Full Text »  |  PDF »

Conditionally Replicative Adenovirus Expressing p53 Exhibits Enhanced Oncolytic Potency.

V. W. van Beusechem, P. B. van den Doel, J. Grill, H. M. Pinedo, and W. R. Gerritsen (2002)
Cancer Res. 62, 6165-6171
 |  Abstract »  |  Full Text »  |  PDF »

Specific Interaction of p53 with Target Binding Sites Is Determined by DNA Conformation and Is Regulated by the C-terminal Domain.

T. Gohler, M. Reimann, D. Cherny, K. Walter, G. Warnecke, E. Kim, and W. Deppert (2002)
J. Biol. Chem. 277, 41192-41203
 |  Abstract »  |  Full Text »  |  PDF »

The Processing of Holliday Junctions by BLM and WRN Helicases Is Regulated by p53.

Q. Yang, R. Zhang, X. W. Wang, E. A. Spillare, S. P. Linke, D. Subramanian, J. D. Griffith, J. L. Li, I. D. Hickson, J. C. Shen, et al. (2002)
J. Biol. Chem. 277, 31980-31987
 |  Abstract »  |  Full Text »  |  PDF »

Human Papillomavirus Oncoprotein E6 Inactivates the Transcriptional Coactivator Human ADA3.

A. Kumar, Y. Zhao, G. Meng, M. Zeng, S. Srinivasan, L. M. Delmolino, Q. Gao, G. Dimri, G. F. Weber, D. E. Wazer, et al. (2002)
Mol. Cell. Biol. 22, 5801-5812
 |  Abstract »  |  Full Text »  |  PDF »

High-throughput measurement of the Tp53 response to anticancer drugs and random compounds using a stably integrated Tp53-responsive luciferase reporter.

T. A. Sohn, R. Bansal, G. H. Su, K. M. Murphy, and S. E. Kern (2002)
Carcinogenesis 23, 949-958
 |  Abstract »  |  Full Text »  |  PDF »

Oncogenic ras and p53 Cooperate To Induce Cellular Senescence.

G. Ferbeyre, E. de Stanchina, A. W. Lin, E. Querido, M. E. McCurrach, G. J. Hannon, and S. W. Lowe (2002)
Mol. Cell. Biol. 22, 3497-3508
 |  Abstract »  |  Full Text »  |  PDF »

Initiation of Human Astrocytoma by Clonal Evolution of Cells with Progressive Loss of p53 Functions in a Patient with a 283H TP53 Germ-line Mutation: Evidence for a Precursor Lesion.

G. Fulci, N. Ishii, D. Maurici, K. M. Gernert, P. Hainaut, B. Kaur, and E. G. Van Meir (2002)
Cancer Res. 62, 2897-2905
 |  Abstract »  |  Full Text »  |  PDF »

Autoinhibitory Regulation of p73 by {Delta}Np73 To Modulate Cell Survival and Death through a p73-Specific Target Element within the {Delta}Np73 Promoter.

T. Nakagawa, M. Takahashi, T. Ozaki, K.-i. Watanabe, S. Todo, H. Mizuguchi, T. Hayakawa, and A. Nakagawara (2002)
Mol. Cell. Biol. 22, 2575-2585
 |  Abstract »  |  Full Text »  |  PDF »

p53 Binds Telomeric Single Strand Overhangs and t-Loop Junctions in Vitro.

R. M. Stansel, D. Subramanian, and J. D. Griffith (2002)
J. Biol. Chem. 277, 11625-11628
 |  Abstract »  |  Full Text »  |  PDF »

Activation of p53 protein by telomeric (TTAGGG)n repeats.

M. Milyavsky, A. Mimran, S. Senderovich, I. Zurer, N. Erez, I. Shats, N. Goldfinger, I. Cohen, and V. Rotter (2001)
Nucleic Acids Res. 29, 5207-5215
 |  Abstract »  |  Full Text »  |  PDF »

An Inherited Mutation Outside the Highly Conserved DNA-Binding Domain of the p53 Tumor Suppressor Protein in Children and Adults with Sporadic Adrenocortical Tumors.

A. C. Latronico, E. M. Pinto, S. Domenice, M. C. B. V. Fragoso, R. M. Martin, M. C. Zerbini, A. M. Lucon, and B. B. Mendonca (2001)
J. Clin. Endocrinol. Metab. 86, 4970-4973
 |  Abstract »  |  Full Text »  |  PDF »

The Role of p53 in Regulating Antiviral T Cell Responses.

J. M. Grayson, J. G. Lanier, J. D. Altman, and R. Ahmed (2001)
J. Immunol. 167, 1333-1337
 |  Abstract »  |  Full Text »  |  PDF »

Imaging transcriptional regulation of p53-dependent genes with positron emission tomography in vivo.

M. Doubrovin, V. Ponomarev, T. Beresten, J. Balatoni, W. Bornmann, R. Finn, J. Humm, S. Larson, M. Sadelain, R. Blasberg, et al. (2001)
PNAS 98, 9300-9305
 |  Abstract »  |  Full Text »  |  PDF »

ZBP-89 Promotes Growth Arrest through Stabilization of p53.

L. Bai and J. L. Merchant (2001)
Mol. Cell. Biol. 21, 4670-4683
 |  Abstract »  |  Full Text »  |  PDF »

Tumor-Suppressor Effect of Interferon Regulatory Factor-1 in Human Hepatocellular Carcinoma.

Y. Moriyama, S. Nishiguchi, A. Tamori, N. Koh, Y. Yano, S. Kubo, K. Hirohashi, and S. Otani (2001)
Clin. Cancer Res. 7, 1293-1298
 |  Abstract »  |  Full Text »

Identification of partial loss of function p53 gene mutations utilizing a yeast-based functional assay.

G. K. Kovvali, B. Mehta, C. B. Epstein, and S. G. Lutzker (2001)
Nucleic Acids Res. 29, e28
 |  Abstract »  |  Full Text »  |  PDF »

RB18A, Whose Gene Is Localized on Chromosome 17q12-q21.1, Regulates in Vivo p53 Transactivating Activity.

R. Frade, M. Balbo, and M. Barel (2000)
Cancer Res. 60, 6585-6589
 |  Abstract »  |  Full Text »

A gain of function p53 mutant promotes both genomic instability and cell survival in a novel p53-null mammary epithelial cell model.

K. L. MURPHY, A. P. DENNIS, and J. M. ROSEN (2000)
FASEB J 14, 2291-2302
 |  Abstract »  |  Full Text »

Role of the Heat Shock Response and Molecular Chaperones in Oncogenesis and Cell Death.

C. Jolly and R. I. Morimoto (2000)
J Natl Cancer Inst 92, 1564-1572
 |  Abstract »  |  Full Text »  |  PDF »

Stimulatory Effect of Oral Administration of Green Tea or Caffeine on Ultraviolet Light-induced Increases in Epidermal Wild-Type p53, p21(WAF1/CIP1), and Apoptotic Sunburn Cells in SKH-1 Mice.

Y.-P. Lu, Y.-R. Lou, X. H. Li, J. G. Xie, D. Brash, M.-T. Huang, and A. H. Conney (2000)
Cancer Res. 60, 4785-4791
 |  Abstract »  |  Full Text »

Repression of RNA Polymerase I Transcription by the Tumor Suppressor p53.

W. Zhai and L. Comai (2000)
Mol. Cell. Biol. 20, 5930-5938
 |  Abstract »  |  Full Text »

MCG10, a Novel p53 Target Gene That Encodes a KH Domain RNA-Binding Protein, Is Capable of Inducing Apoptosis and Cell Cycle Arrest in G2-M.

J. Zhu and X. Chen (2000)
Mol. Cell. Biol. 20, 5602-5618
 |  Abstract »  |  Full Text »

Wild-Type p53 Suppresses Angiogenesis in Human Leiomyosarcoma and Synovial Sarcoma by Transcriptional Suppression of Vascular Endothelial Growth Factor Expression.

L. Zhang, D. Yu, M. Hu, S. Xiong, A. Lang, L. M. Ellis, and R. E. Pollock (2000)
Cancer Res. 60, 3655-3661
 |  Abstract »  |  Full Text »

Analysis of p53-regulated gene expression patterns using oligonucleotide arrays.

R. Zhao, K. Gish, M. Murphy, Y. Yin, D. Notterman, W. H. Hoffman, E. Tom, D. H. Mack, and A. J. Levine (2000)
Genes & Dev. 14, 981-993
 |  Abstract »  |  Full Text »

Enhanced Sensitivity to anti-Benzo(a)pyrene-diol-epoxide DNA Damage Correlates with Decreased Global Genomic Repair Attributable to Abrogated p53 Function in Human Cells.

M. A. Wani, Q. Zhu, M. El-Mahdy, S. Venkatachalam, and A. A. Wani (2000)
Cancer Res. 60, 2273-2280
 |  Abstract »  |  Full Text »

Human and Mouse Fas (APO-1/CD95) Death Receptor Genes Each Contain a p53-responsive Element That Is Activated by p53 Mutants Unable to Induce Apoptosis.

D. Munsch, R. Watanabe-Fukunaga, J.-C. Bourdon, S. Nagata, E. May, E. Yonish-Rouach, and P. Reisdorf (2000)
J. Biol. Chem. 275, 3867-3872
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Signaling Pathways Involving ATM.

M.B. KASTAN, D.-S. LIM, S.-T. KIM, B. XU, and C. CANMAN (2000)
Cold Spring Harb Symp Quant Biol 65, 521-526
 |  Abstract »  |  PDF »

Pharmacological Rescue of Mutant p53 Conformation and Function.

B. A. Foster, H. A. Coffey, M. J. Morin, and F. Rastinejad (1999)
Science 286, 2507-2510
 |  Abstract »  |  Full Text »

One Mechanism for Cell Type-specific Regulation of the bax Promoter by the Tumor Suppressor p53 Is Dictated by the p53 Response Element.

E. C. Thornborrow and J. J. Manfredi (1999)
J. Biol. Chem. 274, 33747-33756
 |  Abstract »  |  Full Text »  |  PDF »

Time Course for Early Adaptive Responses to Ultraviolet B Light in the Epidermis of SKH-1 Mice.

Y.-P. Lu, Y.-R. Lou, P. Yen, D. Mitchell, M.-T. Huang, and A. H. Conney (1999)
Cancer Res. 59, 4591-4602
 |  Abstract »  |  Full Text »  |  PDF »

The interaction between p53 and DNA topoisomerase I is regulated differently in cells with wild-type and mutant p53.

C. Gobert, A. Skladanowski, and A. K. Larsen (1999)
PNAS 96, 10355-10360
 |  Abstract »  |  Full Text »  |  PDF »

Physical Interaction and Functional Antagonism between the RNA Polymerase II Elongation Factor ELL and p53.

N. Shinobu, T. Maeda, T. Aso, T. Ito, T. Kondo, K. Koike, and M. Hatakeyama (1999)
J. Biol. Chem. 274, 17003-17010
 |  Abstract »  |  Full Text »  |  PDF »

Transcriptional Inhibition of p53 by the MLL/MEN Chimeric Protein Found in Myeloid Leukemia.

K. Maki, K. Mitani, T. Yamagata, M. Kurokawa, Y. Kanda, Y. Yazaki, and H. Hirai (1999)
Blood 93, 3216-3224
 |  Abstract »  |  Full Text »  |  PDF »

p53 Is a Transcriptional Activator of the Muscle-specific Phosphoglycerate Mutase Gene and Contributesin Vivo to the Control of Its Cardiac Expression.

P. Ruiz-Lozano, M. L. Hixon, M. W. Wagner, A. I. Flores, S. Ikawa, A. S. Baldwin Jr., K. R. Chien, and A. Gualberto (1999)
Cell Growth Differ. 10, 295-306
 |  Abstract »  |  Full Text »

p73 Function Is Inhibited by Tumor-Derived p53 Mutants in Mammalian Cells.

C. J. Di Como, C. Gaiddon, and C. Prives (1999)
Mol. Cell. Biol. 19, 1438-1449
 |  Abstract »  |  Full Text »  |  PDF »

Specific interaction of mutant p53 with regions of matrix attachment region DNA elements (MARs) with a high potential for base-unpairing.

K. Will, G. Warnecke, L. Wiesmuller, and W. Deppert (1998)
PNAS 95, 13681-13686
 |  Abstract »  |  Full Text »  |  PDF »

Identification of rCop-1, a New Member of the CCN Protein Family, as a Negative Regulator for Cell Transformation.

R. Zhang, L. Averboukh, W. Zhu, H. Zhang, H. Jo, P. J. Dempsey, R. J. Coffey, A. B. Pardee, and P. Liang (1998)
Mol. Cell. Biol. 18, 6131-6141
 |  Abstract »  |  Full Text »

JNK targets p53 ubiquitination and degradation in nonstressed cells.

S. Y. Fuchs, V. Adler, T. Buschmann, Z. Yin, X. Wu, S. N. Jones, and Z.'e. Ronai (1998)
Genes & Dev. 12, 2658-2663
 |  Abstract »  |  Full Text »

Liver-specific Enhancer II Is the Target for the p53-mediated Inhibition of Hepatitis B Viral Gene Expression.

H. Lee, H. T. Kim, and Y. Yun (1998)
J. Biol. Chem. 273, 19786-19791
 |  Abstract »  |  Full Text »  |  PDF »

alpha -Fetoprotein gene sequences mediating Afr2 regulation during liver regeneration.

D. K. Jin, J. Vacher, and M. H. Feuerman (1998)
PNAS 95, 8767-8772
 |  Abstract »  |  Full Text »  |  PDF »

Non-p53 p53RE binding protein, a human transcription factor functionally analogous to P53.

X. Zeng, A. J. Levine, and H. Lu (1998)
PNAS 95, 6681-6686
 |  Abstract »  |  Full Text »  |  PDF »

Cooperative Interactions Between RB and p53 Regulate Cell Proliferation, Cell Senescence, and Apoptosis in Human Vascular Smooth Muscle Cells From Atherosclerotic Plaques.

M. R. Bennett, K. Macdonald, S.-W. Chan, J. J. Boyle, and P. L. Weissberg (1998)
Circ. Res. 82, 704-712
 |  Abstract »  |  Full Text »  |  PDF »

Bax Involvement in p53-Mediated Neuronal Cell Death.

H. Xiang, Y. Kinoshita, C. M. Knudson, S. J. Korsmeyer, P. A. Schwartzkroin, and R. S. Morrison (1998)
J. Neurosci. 18, 1363-1373
 |  Abstract »  |  Full Text »  |  PDF »

Upregulation of Interleukin 8 by Oxygen-deprived Cells in Glioblastoma Suggests a Role in Leukocyte Activation, Chemotaxis, and Angiogenesis.

I. Desbaillets, A.-C. Diserens, N. d. Tribolet, M.-F. Hamou, and E. G.  V. Meir (1997)
J. Exp. Med. 186, 1201-1212
 |  Abstract »  |  Full Text »  |  PDF »

Increased Sensitivity of Human Vascular Smooth Muscle Cells From Atherosclerotic Plaques to p53-Mediated Apoptosis.

M. R. Bennett, T. D. Littlewood, S. M. Schwartz, and P. L. Weissberg (1997)
Circ. Res. 81, 591-599
 |  Abstract »  |  Full Text »

Transcriptional Repression Mediated by the PR Domain Zinc Finger Gene RIZ.

M. Xie, G. Shao, I. M. Buyse, and S. Huang (1997)
J. Biol. Chem. 272, 26360-26366
 |  Abstract »  |  Full Text »  |  PDF »

Activities and response to DNA damage of latent and active sequence-specific DNA binding forms of mouse p53.

Y. Wu, H. Huang, Z. Miner, and M. Kulesz-Martin (1997)
PNAS 94, 8982-8987
 |  Abstract »  |  Full Text »  |  PDF »

Upregulation of the Elongation Factor-1alpha Gene by p53 in Association With Death of an Erythroleukemic Cell Line.

M. V. Kato, H. Sato, M. Nagayoshi, and Y. Ikawa (1997)
Blood 90, 1373-1378
 |  Abstract »  |  Full Text »  |  PDF »

Architectural Accommodation in the Complex of Four p53 DNA Binding Domain Peptides with the p21/waf1/cip1 DNA Response Element.

A. K. Nagaich, V. B. Zhurkin, H. Sakamoto, A. A. Gorin, G. M. Clore, A. M. Gronenborn, E. Appella, and R. E. Harrington (1997)
J. Biol. Chem. 272, 14830-14841
 |  Abstract »  |  Full Text »  |  PDF »

p53 Is Not Required for Regulation of Apoptosis or Radioprotection by Interleukin-3.

A. Silva, A. Wyllie, and M. K.L. Collins (1997)
Blood 89, 2717-2722
 |  Abstract »  |  Full Text »  |  PDF »

UV-induced mutagenesis of human p53 in a vector replicated in Saccharomyces cerevisiae.

D. J. Moshinsky and G. N. Wogan (1997)
PNAS 94, 2266-2271
 |  Abstract »  |  Full Text »  |  PDF »

Dual Control of glut1 Glucose Transporter Gene Expression by Hypoxia and by Inhibition of Oxidative Phosphorylation.

A. Behrooz and F. Ismail-Beigi (1997)
J. Biol. Chem. 272, 5555-5562
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for p53-Mediated Modulation of Neuronal Viability.

H. Xiang, D. W. Hochman, H. Saya, T. Fujiwara, P. A. Schwartzkroin, and R. S. Morrison (1996)
J. Neurosci. 16, 6753-6765
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Mutant p53 Temperature-sensitive DNA Binding.

P. Friedlander, Y. Legros, T. Soussi, and C. Prives (1996)
J. Biol. Chem. 271, 25468-25478
 |  Abstract »  |  Full Text »  |  PDF »

The XPB and XPD DNA helicases are components of the p53-mediated apoptosis pathway..

X W Wang, W Vermeulen, J D Coursen, M Gibson, S E Lupold, K Forrester, G Xu, L Elmore, H Yeh, J H Hoeijmakers, et al. (1996)
Genes & Dev. 10, 1219-1232
 |  Abstract »  |  PDF »

Human Cytomegalovirus Immediate-Early Protein IE2 Tethers a Transcriptional Repression Domain to p53.

H.-L. Tsai, G.-H. Kou, S.-C. Chen, C.-W. Wu, and Y.-S. Lin (1996)
J. Biol. Chem. 271, 3534-3540
 |  Abstract »  |  Full Text »  |  PDF »

Allosteric Regulation of the Thermostability and DNA Binding Activity of Human p53 by Specific Interacting Proteins.

S. Hansen, T. R. Hupp, and D. P. Lane (1996)
J. Biol. Chem. 271, 3917-3924
 |  Abstract »  |  Full Text »  |  PDF »

Hormonal Regulation of the p53 Tumor Suppressor Protein in T47D Human Breast Carcinoma Cell Line.

C. Hurd, N. Khattree, P. Alban, K. Nag, S. C. Jhanwar, S. Dinda, and V. K. Moudgil (1995)
J. Biol. Chem. 270, 28507-28510
 |  Abstract »  |  Full Text »  |  PDF »

Transactivation Ability of p53 Transcriptional Activation Domain Is Directly Related to the Binding Affinity to TATA-binding Protein.

J. Chang, D.-H. Kim, S. W. Lee, K. Y. Choi, and Y. C. Sung (1995)
J. Biol. Chem. 270, 25014-25019
 |  Abstract »  |  Full Text »  |  PDF »

The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis..

S Maheswaran, C Englert, P Bennett, G Heinrich, and D A Haber (1995)
Genes & Dev. 9, 2143-2156
 |  Abstract »  |  PDF »

Induction of apoptosis in HeLa cells by trans-activation-deficient p53..

Y Haupt, S Rowan, E Shaulian, K H Vousden, and M Oren (1995)
Genes & Dev. 9, 2170-2183
 |  Abstract »  |  PDF »

Transcriptional Regulation by p53.

Y.-S. Hsu, F.-M. Tang, W.-L. Liu, J.-Y. Chuang, M.-Y. Lai, and Y.-S. Lin (1995)
J. Biol. Chem. 270, 6966-6974
 |  Abstract »  |  Full Text »  |  PDF »

p53 Is Phosphorylated in Vitro and in Vivo by an Ultraviolet Radiation-induced Protein Kinase Characteristic of the c-Jun Kinase, JNK1.

D. M. Milne, L. E. Campbell, D. G. Campbell, and D. W. Meek (1995)
J. Biol. Chem. 270, 5511-5518
 |  Abstract »  |  Full Text »  |  PDF »

Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms.

P. Jeffrey, S Gorina, and N. Pavletich (1995)
Science 267, 1498-1502
 |  Abstract »  |  PDF »

Wild Type p53 Stimulates Expression from the Human Multidrug Resistance Promoter in a p53-negative Cell Line.

M. E. Goldsmith, J. M. Gudas, E. Schneider, and K. H. Cowan (1995)
J. Biol. Chem. 270, 1894-1898
 |  Abstract »  |  Full Text »  |  PDF »

Coupling between gamma irradiation, p53 induction and the apoptotic response depends upon cell type in vivo.

C. Midgley, B Owens, C. Briscoe, D. Thomas, D. Lane, and P. Hall (1995)
J. Cell Sci. 108, 1843-1848
 |  Abstract »  |  PDF »

In vitro p53 and/or Rb antisense oligonucleotide treatment in association with growth factors induces the proliferation of peripheral hematopoietic progenitors.

T Mahdi, A Brizard, C Millet, P Dore, J Tanzer, and A Kitzis (1995)
J. Cell Sci. 108, 1287-1293
 |  Abstract »  |  PDF »

p53: a glimpse at the puppet behind the shadow play.

S Friend (1994)
Science 265, 334-335
 |  PDF »

Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations.

Y Cho, S Gorina, P. Jeffrey, and N. Pavletich (1994)
Science 265, 346-355
 |  Abstract »  |  PDF »

High-resolution structure of the oligomerization domain of p53 by multidimensional NMR.

G. Clore, J. Omichinski, K Sakaguchi, N Zambrano, H Sakamoto, E Appella, and A. Gronenborn (1994)
Science 265, 386-391
 |  Abstract »  |  PDF »

Prevalence of p53 mutations in patients with squamous cell carcinoma of the esophagus.

C. E. Gates, C. E. Reed, J. S. Bromberg, E. T. Everett, P. L. Baron, and S. b. F. A. Crawford Jr. (1994)
J. Thorac. Cardiovasc. Surg. 108, 148-152
 |  Abstract »  |  Full Text »

c-erbB-2 Expression and Response to Adjuvant Therapy in Women with Node-Positive Early Breast Cancer.

H. B. Muss, A. D. Thor, D. A. Berry, T. Kute, E. T. Liu, F. Koerner, C. T. Cirrincione, D. R. Budman, W. C. Wood, M. Barcos, et al. (1994)
N. Engl. J. Med. 330, 1260-1266
 |  Abstract »  |  Full Text »

Abnormalities of p53 Protein Expression in Cutaneous Disorders.

N. S. McNutt, C. Saenz-Santamaria, M. Volkenandt, C. R. Shea, and A. P. Albino (1994)
Arch Dermatol 130, 225-232
 |  Abstract »  |  PDF »

Adenovirus E1B oncoprotein tethers a transcriptional repression domain to p53..

P R Yew, X Liu, and A J Berk (1994)
Genes & Dev. 8, 190-202
 |  Abstract »  |  PDF »

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