Science 14 June 1991: Vol. 252. no. 5012, pp. 1523 - 1528 DOI: 10.1126/science.2047859

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Articles

IL-6, in Synergy with IL-7 or IL-15, Stimulates TCR-Independent Proliferation and Functional Differentiation of CD8+ T Lymphocytes.

J. Gagnon, S. Ramanathan, C. Leblanc, A. Cloutier, P. P. McDonald, and S. Ilangumaran (2008)
J. Immunol. 180, 7958-7968
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of SOCS3 Phosphorylation upon Interleukin-6 Stimulation: CONTRIBUTIONS OF Src- AND RECEPTOR-TYROSINE KINASES.

U. Sommer, C. Schmid, R. M. Sobota, U. Lehmann, N. J. Stevenson, J. A. Johnston, F. Schaper, P. C. Heinrich, and S. Haan (2005)
J. Biol. Chem. 280, 31478-31488
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-2-induced survival of natural killer (NK) cells involving phosphatidylinositol-3 kinase-dependent reduction of ceramide through acid sphingomyelinase, sphingomyelin synthase, and glucosylceramide synthase.

Y. Taguchi, T. Kondo, M. Watanabe, M. Miyaji, H. Umehara, Y. Kozutsumi, and T. Okazaki (2004)
Blood 104, 3285-3293
 |  Abstract »  |  Full Text »  |  PDF »

Lyn tyrosine kinase regulates thrombopoietin-induced proliferation of hematopoietic cell lines and primary megakaryocytic progenitors.

B. J. Lannutti and J. G. Drachman (2004)
Blood 103, 3736-3743
 |  Abstract »  |  Full Text »  |  PDF »

PEST Domain-Enriched Tyrosine Phosphatase (PEP) Regulation of Effector/Memory T Cells.

K. Hasegawa, F. Martin, G. Huang, D. Tumas, L. Diehl, and A. C. Chan (2004)
Science 303, 685-689
 |  Abstract »  |  Full Text »  |  PDF »

Subdomain X of the Kinase Domain of Lck Binds CD45 and Facilitates Dephosphorylation.

J. Felberg, D. C. Lefebvre, M. Lam, Y. Wang, D. H. W. Ng, D. Birkenhead, J. L. Cross, and P. Johnson (2004)
J. Biol. Chem. 279, 3455-3462
 |  Abstract »  |  Full Text »  |  PDF »

Clinical advances in therapies targeting the interleukin-2 receptor.

A.C. Church (2003)
QJM 96, 91-102
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Regulation of Akt-dependent cell survival by Syk and Rac.

K. Jiang, B. Zhong, C. Ritchey, D. L. Gilvary, E. Hong-Geller, S. Wei, and J. Y. Djeu (2003)
Blood 101, 236-244
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Human T Cell Activation by Novel Src Kinase Inhibitors Is Dependent upon the Complexity of the Signal Delivered to the Cell.

S. Rapecki and R. Allen (2002)
J. Pharmacol. Exp. Ther. 303, 1325-1333
 |  Abstract »  |  Full Text »  |  PDF »

The p85 Regulatory Subunit Controls Sequential Activation of Phosphoinositide 3-Kinase by Tyr Kinases and Ras.

C. Jimenez, C. Hernandez, B. Pimentel, and A. C. Carrera (2002)
J. Biol. Chem. 277, 41556-41562
 |  Abstract »  |  Full Text »  |  PDF »

Function and Molecular Modeling of the Interaction between Human Interleukin 6 and Its HNK-1 Oligosaccharide Ligands.

C. Cebo, V. Durier, P. Lagant, E. Maes, D. Florea, T. Lefebvre, G. Strecker, G. Vergoten, and J.-P. Zanetta (2002)
J. Biol. Chem. 277, 12246-12252
 |  Abstract »  |  Full Text »  |  PDF »

Requirements of src family kinase activity associated with CD45 for myeloma cell proliferation by interleukin-6.

H. Ishikawa, N. Tsuyama, S. Abroun, S. Liu, F.-J. Li, O. Taniguchi, and M. M. Kawano (2002)
Blood 99, 2172-2178
 |  Abstract »  |  Full Text »  |  PDF »

The Src-Protein Tyrosine Kinase Lck Is Required for IL-1-Mediated Costimulatory Signaling in Th2 Cells.

B. K. al-Ramadi, T. Welte, M. J. Fernandez-Cabezudo, S. Galadari, B. Dittel, X.-Y. Fu, and A. L. M. Bothwell (2001)
J. Immunol. 167, 6827-6833
 |  Abstract »  |  Full Text »  |  PDF »

Cytokine-driven Proliferation and Differentiation of Human Naive, Central Memory, and Effector Memory CD4+ T Cells.

J. Geginat, F. Sallusto, and A. Lanzavecchia (2001)
J. Exp. Med. 194, 1711-1720
 |  Abstract »  |  Full Text »  |  PDF »

Signaling through a Novel Domain of gp130 Mediates Cell Proliferation and Activation of Hck and Erk Kinases.

M. Schaeffer, M. Schneiderbauer, S. Weidler, R. Tavares, M. Warmuth, G. de Vos, and M. Hallek (2001)
Mol. Cell. Biol. 21, 8068-8081
 |  Abstract »  |  Full Text »  |  PDF »

The IL-15R{alpha} Chain Signals Through Association with Syk in Human B Cells.

E. Bulanova, V. Budagian, T. Pohl, H. Krause, H. Durkop, R. Paus, and S. Bulfone-Paus (2001)
J. Immunol. 167, 6292-6302
 |  Abstract »  |  Full Text »  |  PDF »

p59fyn (Fyn) Promotes the Survival of Anergic CD4-CD8- {{alpha}}{{beta}} TCR+ Cells but Negatively Regulates Their Proliferative Response to Antigen Stimulation.

O. Utting, J. J. Priatel, S.-J. Teh, and H.-S. Teh (2001)
J. Immunol. 166, 1540-1546
 |  Abstract »  |  Full Text »  |  PDF »

CD8+ T Cells Rapidly Acquire NK1.1 and NK Cell-Associated Molecules Upon Stimulation In Vitro and In Vivo.

E. Assarsson, T. Kambayashi, J. K. Sandberg, S. Hong, M. Taniguchi, L. Van Kaer, H.-G. Ljunggren, and B. J. Chambers (2000)
J. Immunol. 165, 3673-3679
 |  Abstract »  |  Full Text »  |  PDF »

Efficient Internalization of IL-2 Depends on the Distal Portion of the Cytoplasmic Tail of the IL-2R Common {gamma}-Chain and a Lymphoid Cell Environment.

A. Yu, F. Olosz, C. Y. Choi, and T. R. Malek (2000)
J. Immunol. 165, 2556-2562
 |  Abstract »  |  Full Text »  |  PDF »

Hierarchy of Protein Tyrosine Kinases in Interleukin-2 (IL-2) Signaling: Activation of Syk Depends on Jak3; However, Neither Syk nor Lck Is Required for IL-2-Mediated STAT Activation.

Y.-J. Zhou, K. S. Magnuson, T. P. Cheng, M. Gadina, D. M. Frucht, J. Galon, F. Candotti, R. L. Geahlen, P. S. Changelian, and J. J. O'Shea (2000)
Mol. Cell. Biol. 20, 4371-4380
 |  Abstract »  |  Full Text »

IL-2 Signaling in Human Monocytes Involves the Phosphorylation and Activation of p59hck 1.

M. C. Bosco, R. E. Curiel, A. H. Zea, M. G. Malabarba, J. R. Ortaldo, and I. Espinoza-Delgado (2000)
J. Immunol. 164, 4575-4585
 |  Abstract »  |  Full Text »  |  PDF »

Direct Interaction of the CD38 Cytoplasmic Tail and the Lck SH2 Domain. CD38 TRANSDUCES T CELL ACTIVATION SIGNALS THROUGH ASSOCIATED Lck.

Y.-S. Cho, M.-K. Han, Y. B. Choi, Y. Yun, J. Shin, and U.-H. Kim (2000)
J. Biol. Chem. 275, 1685-1690
 |  Abstract »  |  Full Text »  |  PDF »

Lad, an Adapter Protein Interacting with the SH2 Domain of p56lck, Is Required for T Cell Activation ,2.

Y. B. Choi, C. K. Kim, and Y. Yun (1999)
J. Immunol. 163, 5242-5249
 |  Abstract »  |  Full Text »  |  PDF »

Cytokines in asthma.

K F Chung and P J Barnes (1999)
Thorax 54, 825-857
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Mechanisms of T-Cell Activation by Human T-Cell Lymphotropic Virus Type I.

P. Hollsberg (1999)
Microbiol. Mol. Biol. Rev. 63, 308-333
 |  Abstract »  |  Full Text »  |  PDF »

Interactions of CD45-associated Protein with the Antigen Receptor Signaling Machinery in T-lymphocytes.

A. Veillette, D. Soussou, S. Latour, D. Davidson, and F. G. Gervais (1999)
J. Biol. Chem. 274, 14392-14399
 |  Abstract »  |  Full Text »  |  PDF »

Downregulation of JAK3 Protein Levels in T Lymphocytes by Prostaglandin E2 and Other Cyclic Adenosine Monophosphate-Elevating Agents: Impact on Interleukin-2 Receptor Signaling Pathway.

V. Kolenko, P. Rayman, B. Roy, M. K. Cathcart, J. O'Shea, R. Tubbs, L. Rybicki, R. Bukowski, and J. Finke (1999)
Blood 93, 2308-2318
 |  Abstract »  |  Full Text »  |  PDF »

Role of Interleukin (IL)-2 Receptor beta -Chain Subdomains and Shc in p38 Mitogen-activated Protein (MAP) Kinase and p54 MAP Kinase (Stress-activated Protein Kinase/c-Jun N-terminal Kinase) Activation. IL-2-DRIVEN PROLIFERATION IS INDEPENDENT OF p38 AND p54 MAP KINASE ACTIVATION.

A. E. Hunt, F. V. Lali, J. D. Lord, B. H. Nelson, T. Miyazaki, K. J. Tracey, and B. M. J. Foxwell (1999)
J. Biol. Chem. 274, 7591-7597
 |  Abstract »  |  Full Text »  |  PDF »

Physical and Functional Interaction between p72syk and Erythropoietin Receptor.

V. Duprez, U. Blank, S. Chretien, S. Gisselbrecht, and P. Mayeux (1998)
J. Biol. Chem. 273, 33985-33990
 |  Abstract »  |  Full Text »  |  PDF »

Inflammatory Mediators of Asthma: An Update.

P. J. Barnes, K. F. Chung, and C. P. Page (1998)
Pharmacol. Rev. 50, 515-596
 |  Abstract »  |  Full Text »  |  PDF »

Human CD5 Signaling and Constitutive Phosphorylation of C-Terminal Serine Residues by Casein Kinase II.

J. Calvo, J. M. Vilda, L. Places, M. Simarro, O. Padilla, D. Andreu, K. S. Campbell, C. Aussel, and F. Lozano (1998)
J. Immunol. 161, 6022-6029
 |  Abstract »  |  Full Text »  |  PDF »

Conditional Activation of Janus Kinase (JAK) Confers Factor Independence upon Interleukin-3-dependent Cells. ESSENTIAL ROLE OF Ras IN JAK-TRIGGERED MITOGENESIS.

R. Mizuguchi and M. Hatakeyama (1998)
J. Biol. Chem. 273, 32297-32303
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin 2-mediated Uncoupling of T Cell Receptor {alpha}/{beta} from CD3 Signaling.

L. Haughn, B. Leung, L. Boise, A. Veillette, C. Thompson, and M. Julius (1998)
J. Exp. Med. 188, 1575-1586
 |  Abstract »  |  Full Text »  |  PDF »

The IL-2 Receptor Promotes Proliferation, bcl-2 and bcl-x Induction, But Not Cell Viability Through the Adapter Molecule Shc.

J. D. Lord, B. C. McIntosh, P. D. Greenberg, and B. H. Nelson (1998)
J. Immunol. 161, 4627-4633
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Mycobacterium bovis BCG-Induced Tumor Necrosis Factor Alpha Secretion in Human Cells by Transforming Growth Factor beta.

P. Méndez-Samperio, M. Hernandez-Garay, and A. N. Vazquez (1998)
Clin. Vaccine Immunol. 5, 588-591
 |  Abstract »  |  Full Text »

Macrophage-Derived Nitric Oxide Regulates T Cell Activation via Reversible Disruption of the Jak3/STAT5 Signaling Pathway.

R. M. Bingisser, P. A. Tilbrook, P. G. Holt, and U. R. Kees (1998)
J. Immunol. 160, 5729-5734
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-2 induces beta 2-integrin-dependent signal transduction involving the focal adhesion kinase-related protein B (fakB).

J. Brockdorff, S. B. Kanner, M. Nielsen, N. Borregaard, C. Geisler, A. Svejgaard, and N. Odum (1998)
PNAS 95, 6959-6964
 |  Abstract »  |  Full Text »  |  PDF »

Lyn Physically Associates With the Erythropoietin Receptor and May Play a Role in Activation of the Stat5 Pathway.

H. Chin, A. Arai, H. Wakao, R. Kamiyama, N. Miyasaka, and O. Miura (1998)
Blood 91, 3734-3745
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Cell Growth by IL-2: Role of STAT5 in Protection from Apoptosis But Not in Cell Cycle Progression.

J. Zamorano, H. Y. Wang, R. Wang, Y. Shi, G. D. Longmore, and A. D. Keegan (1998)
J. Immunol. 160, 3502-3512
 |  Abstract »  |  Full Text »  |  PDF »

Signal Transduction Pathways Regulating Hematopoietic Differentiation.

T. E. Smithgall (1998)
Pharmacol. Rev. 50, 1-20
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Constitutive Activation of TCR Signaling Molecules in IL-2-Independent Herpesvirus saimiri-Transformed T Cells.

N. Noraz, K. Saha, F. Ottones, S. Smith, and N. Taylor (1998)
J. Immunol. 160, 2042-2045
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-2 Stimulation Induces Tyrosine Phosphorylation of p120-Cbl and CrkL and Formation of Multimolecular Signaling Complexes in T Lymphocytes and Natural Killer Cells.

F. Gesbert, C. Garbay, and J. Bertoglio (1998)
J. Biol. Chem. 273, 3986-3993
 |  Abstract »  |  Full Text »  |  PDF »

Opposite CD4/CD8 Lineage Decisions of CD4+8+ Mouse and Rat Thymocytes to Equivalent Triggering Signals: Correlation with Thymic Expression of a Truncated CD8{alpha} Chain in Mice But Not Rats.

R. Mitnacht, A. Bischof, N. Torres-Nagel, and T. Hunig (1998)
J. Immunol. 160, 700-707
 |  Abstract »  |  Full Text »  |  PDF »

Human Homologue of the Drosophila Discs Large Tumor Suppressor Binds to p56lck Tyrosine Kinase and Shaker Type Kv1.3 Potassium Channel in T Lymphocytes.

T. Hanada, L. Lin, K. G. Chandy, S. S. Oh, and A. H. Chishti (1997)
J. Biol. Chem. 272, 26899-26904
 |  Abstract »  |  Full Text »  |  PDF »

Functional cleavage of the common cytokine receptor gamma  chain (gamma c) by calpain.

M. Noguchi, A. Sarin, M. J. Aman, H. Nakajima, E. W. Shores, P. A. Henkart, and W. J. Leonard (1997)
PNAS 94, 11534-11539
 |  Abstract »  |  Full Text »  |  PDF »

STAT3 Is a Serine Kinase Target in T Lymphocytes. INTERLEUKIN 2 AND T CELL ANTIGEN RECEPTOR SIGNALS CONVERGE UPON SERINE 727.

J. Ng and D. Cantrell (1997)
J. Biol. Chem. 272, 24542-24549
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Proliferation in Response to Interleukins 2 and 7 Requires p38MAP Kinase Activation.

J. B. Crawley, L. Rawlinson, F. V. Lali, T. H. Page, J. Saklatvala, and B. M. J. Foxwell (1997)
J. Biol. Chem. 272, 15023-15027
 |  Abstract »  |  Full Text »  |  PDF »

Intrinsic Signals in the Unique Domain Target p56lckto the Plasma Membrane Independently of CD4.

M.-J. J.E. Bijlmakers, M. Isobe-Nakamura, L. J. Ruddock, and M. Marsh (1997)
J. Cell Biol. 137, 1029-1040
 |  Abstract »  |  Full Text »  |  PDF »

Intermediate Affinity Interleukin-2 Receptor Mediates Survival via a Phosphatidylinositol 3-Kinase-dependent Pathway.

A. Gonzalez-Garcia, I. Merida, C. Martinez-A, and A. C. Carrera (1997)
J. Biol. Chem. 272, 10220-10226
 |  Abstract »  |  Full Text »  |  PDF »

Requirement for an initial signal from the membrane-proximal region of the interleukin 2 receptor gamma c chain for Janus kinase activation leading to T cell proliferation.

B. H. Nelson, B. C. McIntosh, L. L. Rosencrans, and P. D. Greenberg (1997)
PNAS 94, 1878-1883
 |  Abstract »  |  Full Text »  |  PDF »

Erythropoietin Activates Raf1 by an Shc-Independent Pathway in CTLL-EPO-R Cells.

D. L. Barber, C. N. Corless, K. Xia, T. M. Roberts, and A. D. D'Andrea (1997)
Blood 89, 55-64
 |  Abstract »  |  Full Text »  |  PDF »

The Protein-tyrosine Kinase Lck Associates with and Is Phosphorylated by Cdc2.

N. I. Pathan, R. L. Geahlen, and M. L. Harrison (1996)
J. Biol. Chem. 271, 27517-27523
 |  Abstract »  |  Full Text »  |  PDF »

The box1 Domain of the Erythropoietin Receptor Specifies Janus Kinase 2Activation and Functions Mitogenically within an Interleukin 2beta -Receptor Chimera.

N. Jiang, T.-C. He, A. Miyajima, and D. M. Wojchowski (1996)
J. Biol. Chem. 271, 16472-16476
 |  Abstract »  |  Full Text »  |  PDF »

Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor.

J. H. Hanke, J. P. Gardner, R. L. Dow, P. S. Changelian, W. H. Brissette, E. J. Weringer, B. A. Pollok, and P. A. Connelly (1996)
J. Biol. Chem. 271, 695-701
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of Interleukin-2-dependent Signal Transduction through the Shc/Grb2 Adapter Pathway.

G. A. Evans, M. A. Goldsmith, J. A. Johnston, W. Xu, S. R. Weiler, R. Erwin, O. M. Z. Howard, R. T. Abraham, J. J. O'Shea, W. C. Greene, et al. (1995)
J. Biol. Chem. 270, 28858-28863
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Novel Repressive Element in the Proximal lck Promoter.

R. C. Muise-Helmericks and N. Rosen (1995)
J. Biol. Chem. 270, 27538-27543
 |  Abstract »  |  Full Text »  |  PDF »

Defects in B Lymphocyte Maturation and T Lymphocyte Activation in Mice Lacking Jak3.

D. C. Thomis, C. B. Gurniak, E. Tivol, A. H. Sharpe, and L. J. Berg (1995)
Science 270, 794-797
 |  Abstract »  |  PDF »

Syp Associates with gp130 and Janus Kinase 2 in Response to Interleukin-11 in 3T3-L1 Mouse Preadipocytes.

D. K. Fuhrer, G.-S. Feng, and Y.-C. Yang (1995)
J. Biol. Chem. 270, 24826-24830
 |  Abstract »  |  Full Text »  |  PDF »

Association of 75/80-kDa Phosphoproteins and the Tyrosine Kinases Lyn, Fyn, and Lck with the B Cell Molecule CD20.

J. P. Deans, L. Kalt, J. A. Ledbetter, G. L. Schieven, J. B. Bolen, and P. Johnson (1995)
J. Biol. Chem. 270, 22632-22638
 |  Abstract »  |  Full Text »  |  PDF »

Growth Signal Transduction by the Human Interleukin-2 Receptor Requires Cytoplasmic Tyrosines of the beta Chain and Non-tyrosine Residues of the [IMAGE](c) Chain.

M. A. Goldsmith, S. Y. Lai, W. Xu, M. C. Amaral, E. S. Kuczek, L. J. Parent, G. B. Mills, K. L. Tarr, G. D. Longmore, and W. C. Greene (1995)
J. Biol. Chem. 270, 21729-21737
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Lck-binding Elements in Tip of Herpesvirus Saimiri.

J. U. Jung, S. M. Lang, U. Friedrich, T. Jun, T. M. Roberts, R. C. Desrosiers, and B. Biesinger (1995)
J. Biol. Chem. 270, 20660-20667
 |  Abstract »  |  Full Text »  |  PDF »

Cytokine signaling through nonreceptor protein tyrosine kinases.

T Taniguchi (1995)
Science 268, 251-255
 |  Abstract »  |  PDF »

A Membrane Proximal Domain of the Human Interleukin-3 Receptor beta(c) Subunit That Signals DNA Synthesis in NIH 3T3 Cells Specifically Binds a Complex of Src and Janus Family Tyrosine Kinases and Phosphatidylinositol 3-Kinase.

P. Rao and R. A. Mufson (1995)
J. Biol. Chem. 270, 6886-6893
 |  Abstract »  |  Full Text »  |  PDF »

The Product of the Herpesvirus saimiri Open Reading Frame 1 (Tip) Interacts with T Cell-specific Kinase p56[IMAGE] in Transformed Cells.

B. Biesinger, A. Y. Tsygankov, H. Fickenscher, F. Emmrich, B. Fleckenstein, J. B. Bolen, and B. M. Bröker (1995)
J. Biol. Chem. 270, 4729-4734
 |  Abstract »  |  Full Text »  |  PDF »

Choice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptors.

N Stahl, T. Farruggella, T. Boulton, Z Zhong, J. Darnell Jr, and G. Yancopoulos (1995)
Science 267, 1349-1353
 |  Abstract »  |  PDF »

p70 Phosphorylation and Binding to p56[IMAGE] Is an Early Event in Interleukin-2-induced Onset of Cell Cycle Progression in T-lymphocytes.

L. B. Vogel and D. J. Fujita (1995)
J. Biol. Chem. 270, 2506-2511
 |  Abstract »  |  Full Text »  |  PDF »

Both Interleukin 4 and Interleukin 13 Induce Tyrosine Phosphorylation of the 140-kDa Subunit of the Interleukin 4 Receptor.

C. Smerz-Bertling and A. Duschl (1995)
J. Biol. Chem. 270, 966-970
 |  Abstract »  |  Full Text »  |  PDF »

Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits.

T Miyazaki, A Kawahara, H Fujii, Y Nakagawa, Y Minami, Z. Liu, I Oishi, O Silvennoinen, B. Witthuhn, J. Ihle, et al. (1994)
Science 266, 1045-1047
 |  Abstract »  |  PDF »

Renal Transplantation.

M. Suthanthiran and T. B. Strom (1994)
N. Engl. J. Med. 331, 365-376
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Cytokine Receptors in Congenital Hematopoietic Disease.

A. D. D'Andrea (1994)
N. Engl. J. Med. 330, 839-846
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Functional overlap in the src gene family: inactivation of hck and fgr impairs natural immunity..

C A Lowell, P Soriano, and H E Varmus (1994)
Genes & Dev. 8, 387-398
 |  Abstract »  |  PDF »

Trafficking of interleukin 2 and transferrin in endosomal fractions of T lymphocytes.

V Duprez, M Smoljanovic, M Lieb, and A Dautry-Varsat (1994)
J. Cell Sci. 107, 1289-1295
 |  Abstract »  |  PDF »

Requirement for tyrosine kinase p56lck for thymic development of transgenic gamma delta T cells.

J Penninger, K Kishihara, T Molina, V. Wallace, E Timms, S. Hedrick, and T. Mak (1993)
Science 260, 358-361
 |  Abstract »  |  PDF »

Anti-oncogenic and oncogenic potentials of interferon regulatory factors-1 and -2.

H Harada, M Kitagawa, N Tanaka, H Yamamoto, K Harada, M Ishihara, and T Taniguchi (1993)
Science 259, 971-974
 |  Abstract »

Interleukin-6 and its receptor: a paradigm for cytokines.

T Kishimoto, S Akira, and T Taga (1992)
Science 258, 593-597
 |  Abstract »  |  PDF »

Growth factors and cancer.

S. Aaronson (1991)
Science 254, 1146-1153
 |  Abstract »  |  PDF »

The Src Kinase p56lck Up-regulates VLA-4 Integrin Affinity. IMPLICATIONS FOR RAPID SPONTANEOUS AND CHEMOKINE-TRIGGERED T CELL ADHESION TO VCAM-1 AND FIBRONECTIN.

S. W. Feigelson, V. Grabovsky, E. Winter, L. L. Chen, R. B. Pepinsky, T. Yednock, D. Yablonski, R. Lobb, and R. Alon (2001)
J. Biol. Chem. 276, 13891-13901
 |  Abstract »  |  Full Text »  |  PDF »

Identification and Characterization of a Transcriptional Regulator for the lck Proximal Promoter.

A. Yamada, S. Takaki, F. Hayashi, K. Georgopoulos, R. M. Perlmutter, and K. Takatsu (2001)
J. Biol. Chem. 276, 18082-18089
 |  Abstract »  |  Full Text »  |  PDF »

Recombinant Human Interleukins IL-1alpha , IL-1beta , IL-4, IL-6, and IL-7 Show Different and Specific Calcium-independent Carbohydrate-binding Properties.

C. Cebo, T. Dambrouck, E. Maes, C. Laden, G. Strecker, J.-C. Michalski, and J.-P. Zanetta (2001)
J. Biol. Chem. 276, 5685-5691
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-2 Carbohydrate Recognition Modulates CTLL-2 Cell Proliferation.

K. Fukushima and K. Yamashita (2001)
J. Biol. Chem. 276, 7351-7356
 |  Abstract »  |  Full Text »  |  PDF »

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