Science 14 June 1991: Vol. 252. no. 5012, pp. 1515 - 1522 DOI: 10.1126/science.1675487

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Articles

Prion-induced Activation of Cholesterogenic Gene Expression by Srebp2 in Neuronal Cells.

C. Bach, S. Gilch, R. Rost, A. D. Greenwood, M. Horsch, G. N. M. Hajj, S. Brodesser, A. Facius, S. Schadler, K. Sandhoff, et al. (2009)
J. Biol. Chem. 284, 31260-31269
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of Protein Levels of 24 Cytokines in Scrapie Agent-Infected Brain and Glial Cell Cultures from Mice Differing in Prion Protein Expression Levels.

D. Tribouillard-Tanvier, J. F. Striebel, K. E. Peterson, and B. Chesebro (2009)
J. Virol. 83, 11244-11253
 |  Abstract »  |  Full Text »  |  PDF »

Alternative Translation Initiation Generates Cytoplasmic Sheep Prion Protein.

C. Lund, C. M. Olsen, S. Skogtvedt, H. Tveit, K. Prydz, and M. A. Tranulis (2009)
J. Biol. Chem. 284, 19668-19678
 |  Abstract »  |  Full Text »  |  PDF »

Doxorubicin and Congo Red Effectiveness on Prion Infectivity in Golden Syrian Hamster.

M. CORATO, P. OGLIARI, F. CECILIANI, E. COVA, V. BELLOTTI, C. CEREDA, G. MERLINI, and M. CERONI (2009)
Anticancer Res 29, 2507-2512
 |  Abstract »  |  Full Text »  |  PDF »

Design of anti- and pro-aggregation variants to assess the effects of methionine oxidation in human prion protein.

C. Wolschner, A. Giese, H. A. Kretzschmar, R. Huber, L. Moroder, and N. Budisa (2009)
PNAS 106, 7756-7761
 |  Abstract »  |  Full Text »  |  PDF »

Highly sensitive, quantitative cell-based assay for prions adsorbed to solid surfaces.

J. A. Edgeworth, G. S. Jackson, A. R. Clarke, C. Weissmann, and J. Collinge (2009)
PNAS 106, 3479-3483
 |  Abstract »  |  Full Text »  |  PDF »

Alteration of the biological and biochemical characteristics of bovine spongiform encephalopathy prions during interspecies transmission in transgenic mice models.

T. Yokoyama, K. Masujin, Y. Iwamaru, M. Imamura, and S. Mohri (2009)
J. Gen. Virol. 90, 261-268
 |  Abstract »  |  Full Text »  |  PDF »

Prion Strain Targeting Independent of Strain-Specific Neuronal Tropism.

J. I. Ayers, A. E. Kincaid, and J. C. Bartz (2009)
J. Virol. 83, 81-87
 |  Abstract »  |  Full Text »  |  PDF »

Identifying Key Components of the PrPC-PrPSc Replicative Interface.

G. C. Abalos, J. T. Cruite, A. Bellon, S. Hemmers, J. Akagi, J. A. Mastrianni, R. A. Williamson, and L. Solforosi (2008)
J. Biol. Chem. 283, 34021-34028
 |  Abstract »  |  Full Text »  |  PDF »

Histidine at codon 154 of the prion protein gene is a risk factor for Nor98 scrapie in goats.

S. Colussi, G. Vaccari, C. Maurella, C. Bona, R. Lorenzetti, P. Troiano, F. Casalinuovo, A. Di Sarno, M. G. Maniaci, F. Zuccon, et al. (2008)
J. Gen. Virol. 89, 3173-3176
 |  Abstract »  |  Full Text »  |  PDF »

In vitro amplification of PrPSc derived from the brain and blood of sheep infected with scrapie.

L. Thorne and L. A. Terry (2008)
J. Gen. Virol. 89, 3177-3184
 |  Abstract »  |  Full Text »  |  PDF »

The Mad2 partial unfolding model: regulating mitosis through Mad2 conformational switching.

J. J. Skinner, S. Wood, J. Shorter, S. W. Englander, and B. E. Black (2008)
J. Cell Biol. 183, 761-768
 |  Abstract »  |  Full Text »  |  PDF »

Structural changes of membrane-anchored native PrPC.

K. Elfrink, J. Ollesch, J. Stohr, D. Willbold, D. Riesner, and K. Gerwert (2008)
PNAS 105, 10815-10819
 |  Abstract »  |  Full Text »  |  PDF »

Prion strain discrimination in cell culture: The cell panel assay.

S. P. Mahal, C. A. Baker, C. A. Demczyk, E. W. Smith, C. Julius, and C. Weissmann (2007)
PNAS 104, 20908-20913
 |  Abstract »  |  Full Text »  |  PDF »

Prion propagation in a nerve conduit model containing segments devoid of axons.

C. Kratzel, D. Kruger, and M. Beekes (2007)
J. Gen. Virol. 88, 3479-3485
 |  Abstract »  |  Full Text »  |  PDF »

Orally Administered Amyloidophilic Compound Is Effective in Prolonging the Incubation Periods of Animals Cerebrally Infected with Prion Diseases in a Prion Strain-Dependent Manner.

Y. Kawasaki, K. Kawagoe, C.-j. Chen, K. Teruya, Y. Sakasegawa, and K. Doh-ura (2007)
J. Virol. 81, 12889-12898
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: Cell division modulates prion accumulation in cultured cells.

S. Ghaemmaghami, P.-W. Phuan, B. Perkins, J. Ullman, B. C. H. May, F. E. Cohen, and S. B. Prusiner (2007)
PNAS 104, 17971-17976
 |  Abstract »  |  Full Text »  |  PDF »

Cyclodextrins Inhibit Replication of Scrapie Prion Protein in Cell Culture.

M. Prior, S. Lehmann, M.-S. Sy, B. Molloy, and H. E. M. McMahon (2007)
J. Virol. 81, 11195-11207
 |  Abstract »  |  Full Text »  |  PDF »

Urinary excretion and blood level of prions in scrapie-infected hamsters.

Y. Murayama, M. Yoshioka, H. Okada, M. Takata, T. Yokoyama, and S. Mohri (2007)
J. Gen. Virol. 88, 2890-2898
 |  Abstract »  |  Full Text »  |  PDF »

Reduced susceptibility to bovine spongiform encephalopathy prions in transgenic mice expressing a bovine PrP with five octapeptide repeats.

A. Brun, A. Gutierrez-Adan, J. Castilla, B. Pintado, F. Diaz-San Segundo, M. J. Cano, E. Alamillo, J. C. Espinosa, and J. M. Torres (2007)
J. Gen. Virol. 88, 1842-1849
 |  Abstract »  |  Full Text »  |  PDF »

Prions in the peripheral nerves of bovine spongiform encephalopathy-affected cattle.

K. Masujin, D. Matthews, G. A. H. Wells, S. Mohri, and T. Yokoyama (2007)
J. Gen. Virol. 88, 1850-1858
 |  Abstract »  |  Full Text »  |  PDF »

Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans.

S. Yin, N. Pham, S. Yu, C. Li, P. Wong, B. Chang, S.-C. Kang, E. Biasini, P. Tien, D. A. Harris, et al. (2007)
PNAS 104, 7546-7551
 |  Abstract »  |  Full Text »  |  PDF »

Neurotoxic and Gliotrophic Activity of a Synthetic Peptide Homologous to Gerstmann-Straussler-Scheinker Disease Amyloid Protein.

L. Fioriti, N. Angeretti, L. Colombo, A. De Luigi, A. Colombo, C. Manzoni, M. Morbin, F. Tagliavini, M. Salmona, R. Chiesa, et al. (2007)
J. Neurosci. 27, 1576-1583
 |  Abstract »  |  Full Text »  |  PDF »

Sheep-Passaged Bovine Spongiform Encephalopathy Agent Exhibits Altered Pathobiological Properties in Bovine-PrP Transgenic Mice.

J. C. Espinosa, O. Andreoletti, J. Castilla, M. E. Herva, M. Morales, E. Alamillo, F. D. San-Segundo, C. Lacroux, S. Lugan, F. J. Salguero, et al. (2007)
J. Virol. 81, 835-843
 |  Abstract »  |  Full Text »  |  PDF »

Prion infectivity in variant Creutzfeldt-Jakob disease rectum.

J D F Wadsworth, S Joiner, K Fox, J M Linehan, M Desbruslais, S Brandner, E A Asante, and J Collinge (2007)
Gut 56, 90-94
 |  Abstract »  |  Full Text »  |  PDF »

A case-control study of scrapie Nor98 in Norwegian sheep flocks.

P. Hopp, M. K. Omer, and B. T. Heier (2006)
J. Gen. Virol. 87, 3729-3736
 |  Abstract »  |  Full Text »  |  PDF »

A novel, resistance-linked ovine PrP variant and its equivalent mouse variant modulate the in vitro cell-free conversion of rPrP to PrPres.

L. Kirby, W. Goldmann, F. Houston, A. C. Gill, and J. C. Manson (2006)
J. Gen. Virol. 87, 3747-3751
 |  Abstract »  |  Full Text »  |  PDF »

Insoluble Aggregates and Protease-resistant Conformers of Prion Protein in Uninfected Human Brains.

J. Yuan, X. Xiao, J. McGeehan, Z. Dong, I. Cali, H. Fujioka, Q. Kong, G. Kneale, P. Gambetti, and W.-Q. Zou (2006)
J. Biol. Chem. 281, 34848-34858
 |  Abstract »  |  Full Text »  |  PDF »

Prion Proteins with Insertion Mutations Have Altered N-terminal Conformation and Increased Ligand Binding Activity and Are More Susceptible to Oxidative Attack.

S. Yin, S. Yu, C. Li, P. Wong, B. Chang, F. Xiao, S.-C. Kang, H. Yan, G. Xiao, J. Grassi, et al. (2006)
J. Biol. Chem. 281, 10698-10705
 |  Abstract »  |  Full Text »  |  PDF »

Prion infection of mouse neurospheres.

R. K. Giri, R. Young, R. Pitstick, S. J. DeArmond, S. B. Prusiner, and G. A. Carlson (2006)
PNAS 103, 3875-3880
 |  Abstract »  |  Full Text »  |  PDF »

Transmission of Amyloidosis in Offspring of Mice with AApoAII Amyloidosis.

T. Korenaga, J. Yan, J. Sawashita, T. Matsushita, H. Naiki, M. Hosokawa, M. Mori, K. Higuchi, and X. Fu (2006)
Am. J. Pathol. 168, 898-906
 |  Abstract »  |  Full Text »  |  PDF »

The prion protein gene in humans revisited: Lessons from a worldwide resequencing study.

M. Soldevila, A. M. Andres, A. Ramirez-Soriano, T. Marques-Bonet, F. Calafell, A. Navarro, and J. Bertranpetit (2006)
Genome Res. 16, 231-239
 |  Abstract »  |  Full Text »  |  PDF »

Gerstmann-Straussler-Scheinker Disease Amyloid Protein Polymerizes According to the "Dock-and-Lock" Model.

M. Gobbi, L. Colombo, M. Morbin, G. Mazzoleni, E. Accardo, M. Vanoni, E. Del Favero, L. Cantu, D. A. Kirschner, C. Manzoni, et al. (2006)
J. Biol. Chem. 281, 843-849
 |  Abstract »  |  Full Text »  |  PDF »

Absence of Spiroplasma or Other Bacterial 16S rRNA Genes in Brain Tissue of Hamsters with Scrapie.

I. Alexeeva, E. J. Elliott, S. Rollins, G. E. Gasparich, J. Lazar, and R. G. Rohwer (2006)
J. Clin. Microbiol. 44, 91-97
 |  Abstract »  |  Full Text »  |  PDF »

Potential Role of Soil in the Transmission of Prion Disease.

P. T. Schramm, C. J. Johnson, N. E. Mathews, D. McKenzie, J. M. Aiken, and J. A. Pedersen (2006)
Reviews in Mineralogy and Geochemistry 64, 135-152
 |  Full Text »  |  PDF »

Overexpression of PrPC by Adenovirus-Mediated Gene Targeting Reduces Ischemic Injury in a Stroke Rat Model.

W.-C. Shyu, S.-Z. Lin, M.-F. Chiang, D.-C. Ding, K.-W. Li, S.-F. Chen, H.-I Yang, and H. Li (2005)
J. Neurosci. 25, 8967-8977
 |  Abstract »  |  Full Text »  |  PDF »

PrP glycoforms are associated in a strain-specific ratio in native PrPSc.

A. Khalili-Shirazi, L. Summers, J. Linehan, G. Mallinson, D. Anstee, S. Hawke, G. S. Jackson, and J. Collinge (2005)
J. Gen. Virol. 86, 2635-2644
 |  Abstract »  |  Full Text »  |  PDF »

Role of Plasminogen in Propagation of Scrapie.

M. Salmona, R. Capobianco, L. Colombo, A. De Luigi, G. Rossi, M. Mangieri, G. Giaccone, E. Quaglio, R. Chiesa, M. B. Donati, et al. (2005)
J. Virol. 79, 11225-11230
 |  Abstract »  |  Full Text »  |  PDF »

Search for a Prion-Specific Nucleic Acid.

J. G. Safar, K. Kellings, A. Serban, D. Groth, J. E. Cleaver, S. B. Prusiner, and D. Riesner (2005)
J. Virol. 79, 10796-10806
 |  Abstract »  |  Full Text »  |  PDF »

Elimination of transmissible spongiform encephalopathy infectivity and decontamination of surgical instruments by using radio-frequency gas-plasma treatment.

H. C. Baxter, G. A. Campbell, A. G. Whittaker, A. C. Jones, A. Aitken, A. H. Simpson, M. Casey, L. Bountiff, L. Gibbard, and R. L. Baxter (2005)
J. Gen. Virol. 86, 2393-2399
 |  Abstract »  |  Full Text »  |  PDF »

Molecular neurology of prion disease.

J Collinge (2005)
J. Neurol. Neurosurg. Psychiatry 76, 906-919
 |  Abstract »  |  Full Text »  |  PDF »

Beyond the Signal Sequence: Protein Routing in Health and Disease.

C. Castro-Fernandez, G. Maya-Nunez, and P. M. Conn (2005)
Endocr. Rev. 26, 479-503
 |  Abstract »  |  Full Text »  |  PDF »

Screening of 145 Anti-PrP Monoclonal Antibodies for Their Capacity to Inhibit PrPSc Replication in Infected Cells.

C. Feraudet, N. Morel, S. Simon, H. Volland, Y. Frobert, C. Creminon, D. Vilette, S. Lehmann, and J. Grassi (2005)
J. Biol. Chem. 280, 11247-11258
 |  Abstract »  |  Full Text »  |  PDF »

Protein Conformation Significantly Influences Immune Responses to Prion Protein.

A. Khalili-Shirazi, S. Quaratino, M. Londei, L. Summers, M. Tayebi, A. R. Clarke, S. H. Hawke, G. S. Jackson, and J. Collinge (2005)
J. Immunol. 174, 3256-3263
 |  Abstract »  |  Full Text »  |  PDF »

Abnormal prion protein in genetically resistant sheep from a scrapie-infected flock.

J.-Y. Madec, S. Simon, S. Lezmi, A. Bencsik, J. Grassi, and T. Baron (2004)
J. Gen. Virol. 85, 3483-3486
 |  Abstract »  |  Full Text »  |  PDF »

Prion protein gene (PRNP) variants and evidence for strong purifying selection in functionally important regions of bovine exon 3.

C. M. Seabury, R. L. Honeycutt, A. P. Rooney, N. D. Halbert, and J. N. Derr (2004)
PNAS 101, 15142-15147
 |  Abstract »  |  Full Text »  |  PDF »

Role of Microglia in Central Nervous System Infections.

R. B. Rock, G. Gekker, S. Hu, W. S. Sheng, M. Cheeran, J. R. Lokensgard, and P. K. Peterson (2004)
Clin. Microbiol. Rev. 17, 942-964
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of two distinct prion strains derived from bovine spongiform encephalopathy transmissions to inbred mice.

S. E. Lloyd, J. M. Linehan, M. Desbruslais, S. Joiner, J. Buckell, S. Brandner, J. D. F. Wadsworth, and J. Collinge (2004)
J. Gen. Virol. 85, 2471-2478
 |  Abstract »  |  Full Text »  |  PDF »

Methionine 129 Variant of Human Prion Protein Oligomerizes More Rapidly than the Valine 129 Variant: IMPLICATIONS FOR DISEASE SUSCEPTIBILITY TO CREUTZFELDT-JAKOB DISEASE.

A. Tahiri-Alaoui, A. C. Gill, P. Disterer, and W. James (2004)
J. Biol. Chem. 279, 31390-31397
 |  Abstract »  |  Full Text »  |  PDF »

Standards for the assay of Creutzfeldt-Jakob disease specimens.

P. Minor, J. Newham, N. Jones, C. Bergeron, L. Gregori, D. Asher, F. van Engelenburg, T. Stroebel, M. Vey, G. Barnard, et al. (2004)
J. Gen. Virol. 85, 1777-1784
 |  Abstract »  |  Full Text »  |  PDF »

Amyloid imaging probes are useful for detection of prion plaques and treatment of transmissible spongiform encephalopathies.

K. Ishikawa, K. Doh-ura, Y. Kudo, N. Nishida, I. Murakami-Kubo, Y. Ando, T. Sawada, and T. Iwaki (2004)
J. Gen. Virol. 85, 1785-1790
 |  Abstract »  |  Full Text »  |  PDF »

Subclinical Bovine Spongiform Encephalopathy Infection in Transgenic Mice Expressing Porcine Prion Protein.

J. Castilla, A. Gutierrez-Adan, A. Brun, D. Doyle, B. Pintado, M. A. Ramirez, F. J. Salguero, B. Parra, F. D. S. Segundo, J. M. Sanchez-Vizcaino, et al. (2004)
J. Neurosci. 24, 5063-5069
 |  Abstract »  |  Full Text »  |  PDF »

Tissue Distribution, Biochemical Properties, and Transmission of Mouse Type A AApoAII Amyloid Fibrils.

T. Korenaga, X. Fu, Y. Xing, T. Matsusita, K. Kuramoto, S. Syumiya, K. Hasegawa, H. Naiki, M. Ueno, T. Ishihara, et al. (2004)
Am. J. Pathol. 164, 1597-1606
 |  Abstract »  |  Full Text »  |  PDF »

Different Behavior toward Bovine Spongiform Encephalopathy Infection of Bovine Prion Protein Transgenic Mice with One Extra Repeat Octapeptide Insert Mutation.

J. Castilla, A. Gutierrez-Adan, A. Brun, B. Pintado, B. Parra, M. A. Ramirez, F. J. Salguero, F. Diaz San Segundo, A. Rabano, M. J. Cano, et al. (2004)
J. Neurosci. 24, 2156-2164
 |  Abstract »  |  Full Text »  |  PDF »

From conversion to aggregation: Protofibril formation of the prion protein.

M. L. DeMarco and V. Daggett (2004)
PNAS 101, 2293-2298
 |  Abstract »  |  Full Text »  |  PDF »

Quinoline Derivatives Are Therapeutic Candidates for Transmissible Spongiform Encephalopathies.

I. Murakami-Kubo, K. Doh-ura, K. Ishikawa, S. Kawatake, K. Sasaki, J.-i. Kira, S. Ohta, and T. Iwaki (2004)
J. Virol. 78, 1281-1288
 |  Abstract »  |  Full Text »  |  PDF »

Strain-specific Kinetics of Prion Protein Formation in Vitro and in Vivo.

E. R. Mulcahy and R. A. Bessen (2004)
J. Biol. Chem. 279, 1643-1649
 |  Abstract »  |  Full Text »  |  PDF »

Reduced proteinase K resistance and infectivity of prions after pressure treatment at 60 {degrees}C.

A. Fernandez Garcia, P. Heindl, H. Voigt, M. Buttner, D. Wienhold, P. Butz, J. Starke, B. Tauscher, and E. Pfaff (2004)
J. Gen. Virol. 85, 261-264
 |  Abstract »  |  Full Text »  |  PDF »

Delay in onset of prion disease for the HY strain of transmissible mink encephalopathy as a result of prior peripheral inoculation with the replication-deficient DY strain.

J. C. Bartz, J. M. Aiken, and R. A. Bessen (2004)
J. Gen. Virol. 85, 265-273
 |  Abstract »  |  Full Text »  |  PDF »

Structural Properties of Gerstmann-Straussler-Scheinker Disease Amyloid Protein.

M. Salmona, M. Morbin, T. Massignan, L. Colombo, G. Mazzoleni, R. Capobianco, L. Diomede, F. Thaler, L. Mollica, G. Musco, et al. (2003)
J. Biol. Chem. 278, 48146-48153
 |  Abstract »  |  Full Text »  |  PDF »

Formation of Critical Oligomers Is a Key Event during Conformational Transition of Recombinant Syrian Hamster Prion Protein.

F. Sokolowski, A. J. Modler, R. Masuch, D. Zirwer, M. Baier, G. Lutsch, D. A. Moss, K. Gast, and D. Naumann (2003)
J. Biol. Chem. 278, 40481-40492
 |  Abstract »  |  Full Text »  |  PDF »

A quantitative, highly sensitive cell-based infectivity assay for mouse scrapie prions.

P.-C. Klohn, L. Stoltze, E. Flechsig, M. Enari, and C. Weissmann (2003)
PNAS 100, 11666-11671
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of prion protein structural integrity by geldanamycin.

H.-J. Ochel, G. Gademann, J. Trepel, and L. Neckers (2003)
Glycobiology 13, 655-660
 |  Abstract »  |  Full Text »  |  PDF »

Evaluation of Quinacrine Treatment for Prion Diseases.

A. Barret, F. Tagliavini, G. Forloni, C. Bate, M. Salmona, L. Colombo, A. De Luigi, L. Limido, S. Suardi, G. Rossi, et al. (2003)
J. Virol. 77, 8462-8469
 |  Abstract »  |  Full Text »  |  PDF »

In vitro cell-free conversion of bacterial recombinant PrP to PrPres as a model for conversion.

L. Kirby, C. R. Birkett, H. Rudyk, I. H. Gilbert, and J. Hope (2003)
J. Gen. Virol. 84, 1013-1020
 |  Abstract »  |  Full Text »  |  PDF »

One O-linked sugar can affect the coil-to-beta structural transition of the prion peptide.

P.-Y. Chen, C.-C. Lin, Y.-T. Chang, S.-C. Lin, and S. I. Chan (2002)
PNAS 99, 12633-12638
 |  Abstract »  |  Full Text »  |  PDF »

Unhampered Prion Neuroinvasion despite Impaired Fast Axonal Transport in Transgenic Mice Overexpressing Four-Repeat Tau.

V. Kunzi, M. Glatzel, M. Y. Nakano, U. F. Greber, F. Van Leuven, and A. Aguzzi (2002)
J. Neurosci. 22, 7471-7477
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Protein Conformational Change in Mouse Senile Amyloidosis.

Y. Xing, A. Nakamura, T. Korenaga, Z. Guo, J. Yao, X. Fu, T. Matsushita, K. Kogishi, M. Hosokawa, F. Kametani, et al. (2002)
J. Biol. Chem. 277, 33164-33169
 |  Abstract »  |  Full Text »  |  PDF »

Presenile dementia syndromes: an update on taxonomy and diagnosis.

M D Greicius, M D Geschwind, and B L Miller (2002)
J. Neurol. Neurosurg. Psychiatry 72, 691-700
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of Thermodynamic Diversity between Transmissible Spongiform Encephalopathy Agent Strains and Its Theoretical Implications.

R. A. Somerville, R. C. Oberthur, U. Havekost, F. MacDonald, D. M. Taylor, and A. G. Dickinson (2002)
J. Biol. Chem. 277, 11084-11089
 |  Abstract »  |  Full Text »  |  PDF »

Prion protein gene polymorphisms in natural goat scrapie.

C. Billinis, C. H. Panagiotidis, V. Psychas, S. Argyroudis, A. Nicolaou, S. Leontides, O. Papadopoulos, and T. Sklaviadis (2002)
J. Gen. Virol. 83, 713-721
 |  Abstract »  |  Full Text »  |  PDF »

PrP Expression and Replication by Schwann Cells: Implications in Prion Spreading.

J. Follet, C. Lemaire-Vieille, F. Blanquet-Grossard, V. Podevin-Dimster, S. Lehmann, J.-P. Chauvin, J.-P. Decavel, R. Varea, J. Grassi, M. Fontes, et al. (2002)
J. Virol. 76, 2434-2439
 |  Abstract »  |  Full Text »  |  PDF »

Use of a Marker Organism To Model the Spread of Central Nervous System Tissue in Cattle and the Abattoir Environment during Commercial Stunning and Carcass Dressing.

D. J. Daly, D. M. Prendergast, J. J. Sheridan, I. S. Blair, and D. A. McDowell (2002)
Appl. Envir. Microbiol. 68, 791-798
 |  Abstract »  |  Full Text »  |  PDF »

The Use of Antioxidants in Transmissible Spongiform Encephalopathies: A Case Report.

J. A. Drisko (2002)
J. Am. Coll. Nutr. 21, 22-25
 |  Abstract »  |  Full Text »  |  PDF »

A Critical Review of the Nature of the Spongiform Encephalopathy Agent: Protein Theory Versus Virus Theory.

H. Narang (2002)
Experimental Biology and Medicine 227, 4-19
 |  Abstract »  |  Full Text »  |  PDF »

Sheep Prion Protein Synthetic Peptide Spanning Helix 1 and beta -Strand 2 (Residues 142-166) Shows beta -Hairpin Structure in Solution.

S. A. Kozin, G. Bertho, A. K. Mazur, H. Rabesona, J.-P. Girault, T. Haertle, M. Takahashi, P. Debey, and G. H. B. Hoa (2001)
J. Biol. Chem. 276, 46364-46370
 |  Abstract »  |  Full Text »  |  PDF »

Prion Protein Fragment PrP-(106-126) Induces Apoptosis via Mitochondrial Disruption in Human Neuronal SH-SY5Y Cells.

C. N. O'Donovan, D. Tobin, and T. G. Cotter (2001)
J. Biol. Chem. 276, 43516-43523
 |  Abstract »  |  Full Text »  |  PDF »

Deletion of {beta}-Strand and {alpha}-Helix Secondary Structure in Normal Prion Protein Inhibits Formation of Its Protease-Resistant Isoform.

I. Vorberg, K. Chan, and S. A. Priola (2001)
J. Virol. 75, 10024-10032
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A Critical Review of Atypical Cerebellum-Type Creutzfeldt-Jakob Disease: Its Relationship to ``New Variant'' CJD and Bovine Spongiform Encephalopathy.

H. K. Narang (2001)
Experimental Biology and Medicine 226, 629-639
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Neurodegenerative Diseases and Prions.

S. B. Prusiner (2001)
N. Engl. J. Med. 344, 1516-1526
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PoPMuSiC, an algorithm for predicting protein mutant stability changes. Application to prion proteins.

D. Gilis and M. Rooman (2000)
Protein Eng. Des. Sel. 13, 849-856
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Physiological Expression of the Gene for PrP-Like Protein, PrPLP/Dpl, by Brain Endothelial Cells and its Ectopic Expression in Neurons of PrP-Deficient Mice Ataxic Due to Purkinje Cell Degeneration.

A. Li, S. Sakaguchi, K. Shigematsu, R. Atarashi, B. C. Roy, R. Nakaoke, K. Arima, N. Okimura, J. Kopacek, and S. Katamine (2000)
Am. J. Pathol. 157, 1447-1452
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Strain-specific propagation of PrPSc properties into baculovirus-expressed hamster PrPC.

V. Iniguez, D. McKenzie, J. Mirwald, and J. Aiken (2000)
J. Gen. Virol. 81, 2565-2571
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Molecular dynamics simulation of human prion protein including both N-linked oligosaccharides and the GPI anchor.

J. Zuegg and J. E. Gready (2000)
Glycobiology 10, 959-974
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Follicular Dendritic Cells and Dissemination of Creutzfeldt-Jakob Disease.

L. Manuelidis, I. Zaitsev, P. Koni, Z. Yun Lu, R. A. Flavell, and W. Fritch (2000)
J. Virol. 74, 8614-8622
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Creutzfeldt-Jakob disease with a novel four extra-repeat insertional mutation in the PrP gene.

G. Rossi, G. Giaccone, L. Giampaolo, S. Iussich, G. Puoti, M. Frigo, G. Cavaletti, L. Frattola, O. Bugiani, and F. Tagliavini (2000)
Neurology 55, 405-410
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Adaptation and Selection of Prion Protein Strain Conformations following Interspecies Transmission of Transmissible Mink Encephalopathy.

J. C. Bartz, R. A. Bessen, D. McKenzie, R. F. Marsh, and J. M. Aiken (2000)
J. Virol. 74, 5542-5547
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Dominant-Negative Inhibition of Prion Formation Diminished by Deletion Mutagenesis of the Prion Protein.

L. Zulianello, K. Kaneko, M. Scott, S. Erpel, D. Han, F. E. Cohen, and S. B. Prusiner (2000)
J. Virol. 74, 4351-4360
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Successful Transmission of Three Mouse-Adapted Scrapie Strains to Murine Neuroblastoma Cell Lines Overexpressing Wild-Type Mouse Prion Protein.

N. Nishida, D. A. Harris, D. Vilette, H. Laude, Y. Frobert, J. Grassi, D. Casanova, O. Milhavet, and S. Lehmann (2000)
J. Virol. 74, 320-325
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Upregulation of the Genes Encoding Lysosomal Hydrolases, a Perforin-Like Protein, and Peroxidases in the Brains of Mice Affected with an Experimental Prion Disease.

J. Kopacek, S. Sakaguchi, K. Shigematsu, N. Nishida, R. Atarashi, R. Nakaoke, R. Moriuchi, M. Niwa, and S. Katamine (2000)
J. Virol. 74, 411-417
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Glycosylation differences between the normal and pathogenic prion protein isoforms.

P. M. Rudd, T. Endo, C. Colominas, D. Groth, S. F. Wheeler, D. J. Harvey, M. R. Wormald, H. Serban, S. B. Prusiner, A. Kobata, et al. (1999)
PNAS 96, 13044-13049
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PrP gene polymorphism and natural scrapie in Icelandic sheep.

S. Thorgeirsdottir, S. Sigurdarson, H. M. Thorisson, G. Georgsson, and A. Palsdottir (1999)
J. Gen. Virol. 80, 2527-2534
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Folding funnels and binding mechanisms.

B. Ma, S. Kumar, C.-J. Tsai, and R. Nussinov (1999)
Protein Eng. Des. Sel. 12, 713-720
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Sphingolipid Depletion Increases Formation of the Scrapie Prion Protein in Neuroblastoma Cells Infected with Prions.

N. Naslavsky, H. Shmeeda, G. Friedlander, A. Yanai, A. H. Futerman, Y. Barenholz, and A. Taraboulos (1999)
J. Biol. Chem. 274, 20763-20771
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A Delicate Balance: Homeostatic Control of Copper Uptake and Distribution.

M. M. O. Peña, J. Lee, and D. J. Thiele (1999)
J. Nutr. 129, 1251-1260
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Effectiveness of Polyene Antibiotics in Treatment of Transmissible Spongiform Encephalopathy in Transgenic Mice Expressing Syrian Hamster PrP Only in Neurons.

R. Demaimay, R. Race, and B. Chesebro (1999)
J. Virol. 73, 3511-3513
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Reversible Conversion of Monomeric Human Prion Protein Between Native and Fibrilogenic Conformations.

G. S. Jackson, L. L. Hosszu, A. Power, A. F. Hill, J. Kenney, H. Saibil, C. J. Craven, J. P. Waltho, A. R. Clarke, and J. Collinge (1999)
Science 283, 1935-1937
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Molecular Genetics of Transmissible Spongiform Encephalopathies.

C. Weissmann (1999)
J. Biol. Chem. 274, 3-6
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Expression of Cellular Prion Protein in Activated Hepatic Stellate Cells.

K. Ikeda, N. Kawada, Y. Q. Wang, H. Kadoya, K. Nakatani, M. Sato, and K. Kaneda (1998)
Am. J. Pathol. 153, 1695-1700
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