Science 8 March 1991: Vol. 251. no. 4998, pp. 1225 - 1228 DOI: 10.1126/science.1900951

Prev | Table of Contents | Next

Articles

Interferon-{gamma} and interleukin-4 reciprocally regulate CD8 expression in CD8+ T cells.

S. H. Apte, A. Baz, P. Groves, A. Kelso, and N. Kienzle (2008)
PNAS 105, 17475-17480
 |  Abstract »  |  Full Text »  |  PDF »

SIT and TRIM Determine T Cell Fate in the Thymus.

U. Koelsch, B. Schraven, and L. Simeoni (2008)
J. Immunol. 181, 5930-5939
 |  Abstract »  |  Full Text »  |  PDF »

IL-15 Serves as a Costimulator in Determining the Activity of Autoreactive CD8 T Cells in an Experimental Mouse Model of Graft-versus-Host-Like Disease.

F. Miyagawa, Y. Tagaya, B. S. Kim, H. J. Patel, K. Ishida, T. Ohteki, T. A. Waldmann, and S. I. Katz (2008)
J. Immunol. 181, 1109-1119
 |  Abstract »  |  Full Text »  |  PDF »

IL-6, in Synergy with IL-7 or IL-15, Stimulates TCR-Independent Proliferation and Functional Differentiation of CD8+ T Lymphocytes.

J. Gagnon, S. Ramanathan, C. Leblanc, A. Cloutier, P. P. McDonald, and S. Ilangumaran (2008)
J. Immunol. 180, 7958-7968
 |  Abstract »  |  Full Text »  |  PDF »

Detuning CD8 T cells: down-regulation of CD8 expression, tetramer binding, and response during CTL activation.

Z. Xiao, M. F. Mescher, and S. C. Jameson (2007)
J. Exp. Med. 204, 2667-2677
 |  Abstract »  |  Full Text »  |  PDF »

Programmed death-1 (PD-1) defines a transient and dysfunctional oligoclonal T cell population in acute homeostatic proliferation.

S.-J. Lin, C. D. Peacock, K. Bahl, and R. M. Welsh (2007)
J. Exp. Med. 204, 2321-2333
 |  Abstract »  |  Full Text »  |  PDF »

Xenogeneic beta2-Microglobulin Substitution Affects Functional Binding of MHC Class I Molecules by CD8+ T Cells.

L. A. Benoit and R. Tan (2007)
J. Immunol. 179, 3588-3595
 |  Abstract »  |  Full Text »  |  PDF »

An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2.

J.-H. Cho, O. Boyman, H.-O. Kim, B. Hahm, M. P. Rubinstein, C. Ramsey, D. M. Kim, C. D. Surh, and J. Sprent (2007)
J. Exp. Med. 204, 1787-1801
 |  Abstract »  |  Full Text »  |  PDF »

Dysregulation of IL-15-mediated T-cell homeostasis in TGF-beta dominant-negative receptor transgenic mice.

P. J. Lucas, S.-J. Kim, C. L. Mackall, W. G. Telford, Y.-W. Chu, F. T. Hakim, and R. E. Gress (2006)
Blood 108, 2789-2795
 |  Abstract »  |  Full Text »  |  PDF »

Functional and Molecular Comparison of Anergic and Regulatory T Lymphocytes..

B. Knoechel, J. Lohr, S. Zhu, L. Wong, D. Hu, L. Ausubel, and A. K. Abbas (2006)
J. Immunol. 176, 6473-6483
 |  Abstract »  |  Full Text »  |  PDF »

Suppressor of Cytokine Signaling 1 Stringently Regulates Distinct Functions of IL-7 and IL-15 In Vivo during T Lymphocyte Development and Homeostasis.

S. Ramanathan, J. Gagnon, C. Leblanc, R. Rottapel, and S. Ilangumaran (2006)
J. Immunol. 176, 4029-4041
 |  Abstract »  |  Full Text »  |  PDF »

Adaptive Tolerance and Clonal Anergy Are Distinct Biochemical States.

L. Chiodetti, S. Choi, D. L. Barber, and R. H. Schwartz (2006)
J. Immunol. 176, 2279-2291
 |  Abstract »  |  Full Text »  |  PDF »

CD11chigh Dendritic Cell Ablation Impairs Lymphopenia-Driven Proliferation of Naive and Memory CD8+ T Cells.

T. Zaft, A. Sapoznikov, R. Krauthgamer, D. R. Littman, and S. Jung (2005)
J. Immunol. 175, 6428-6435
 |  Abstract »  |  Full Text »  |  PDF »

SOCS-1 regulates IL-15-driven homeostatic proliferation of antigen-naive CD8 T cells, limiting their autoimmune potential.

G. M. Davey, R. Starr, A. L. Cornish, J. T. Burghardt, W. S. Alexander, F. R. Carbone, C. D. Surh, and W. R. Heath (2005)
J. Exp. Med. 202, 1099-1108
 |  Abstract »  |  Full Text »  |  PDF »

Functional avidity directs T-cell fate in autoreactive CD4+ T cells.

R. Mallone, S. A. Kochik, H. Reijonen, B. Carson, S. F. Ziegler, W. W. Kwok, and G. T. Nepom (2005)
Blood 106, 2798-2805
 |  Abstract »  |  Full Text »  |  PDF »

Reduction of Runx1 Transcription Factor Activity Up-Regulates Fas and Bim Expression and Enhances the Apoptotic Sensitivity of Double Positive Thymocytes.

N. Abe, K. Kohu, H. Ohmori, K. Hayashi, T. Watanabe, K. Hozumi, T. Sato, S. Habu, and M. Satake (2005)
J. Immunol. 175, 4475-4482
 |  Abstract »  |  Full Text »  |  PDF »

The timing of TCR{alpha} expression critically influences T cell development and selection.

T. A. Baldwin, M. M. Sandau, S. C. Jameson, and K. A. Hogquist (2005)
J. Exp. Med. 202, 111-121
 |  Abstract »  |  Full Text »  |  PDF »

Gamma Interferon-Induced T-Cell Loss in Virulent Mycobacterium avium Infection.

M. Florido, J. E. Pearl, A. Solache, M. Borges, L. Haynes, A. M. Cooper, and R. Appelberg (2005)
Infect. Immun. 73, 3577-3586
 |  Abstract »  |  Full Text »  |  PDF »

Inducing P-Selectin Ligand Formation in CD8 T Cells: IL-2 and IL-12 Are Active In Vitro but Not Required In Vivo.

D. A. Carlow, M. J. Williams, and H. J. Ziltener (2005)
J. Immunol. 174, 3959-3966
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Recent Immune Status Determines the Source of Antigens That Drive Homeostatic T Cell Expansion.

W. C. Kieper, A. Troy, J. T. Burghardt, C. Ramsey, J. Y. Lee, H.-Q. Jiang, W. Dummer, H. Shen, J. J. Cebra, and C. D. Surh (2005)
J. Immunol. 174, 3158-3163
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Requirements for Deletion versus Anergy during CD8 T Cell Peripheral Tolerance In Vivo.

W. L. Redmond, B. C. Marincek, and L. A. Sherman (2005)
J. Immunol. 174, 2046-2053
 |  Abstract »  |  Full Text »  |  PDF »

Peripheral "CD8 Tuning" Dynamically Modulates the Size and Responsiveness of an Antigen-Specific T Cell Pool In Vivo.

R. Maile, C. A. Siler, S. E. Kerry, K. E. Midkiff, E. J. Collins, and J. A. Frelinger (2005)
J. Immunol. 174, 619-627
 |  Abstract »  |  Full Text »  |  PDF »

CTLA-4 Engagement Acts as a Brake on CD4+ T Cell Proliferation and Cytokine Production but Is Not Required for Tuning T Cell Reactivity in Adaptive Tolerance.

M. Inobe and R. H. Schwartz (2004)
J. Immunol. 173, 7239-7248
 |  Abstract »  |  Full Text »  |  PDF »

Age-related CD8 T Cell Clonal Expansions Constrict CD8 T Cell Repertoire and Have the Potential to Impair Immune Defense.

I. Messaoudi, J. LeMaoult, J. A. Guevara-Patino, B. M. Metzner, and J. Nikolich-Zugich (2004)
J. Exp. Med. 200, 1347-1358
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Unresponsiveness Limits Tumor Protection by Adoptively Transferred MDM2-Specific Cytotoxic T Lymphocytes.

G. M. Bendle, A. Holler, L.-K. Pang, S. Hsu, M. Krampera, E. Simpson, and H. J. Stauss (2004)
Cancer Res. 64, 8052-8056
 |  Abstract »  |  Full Text »  |  PDF »

Flt3 ligand enhances thymic-dependent and thymic-independent immune reconstitution.

T. J. Fry, M. Sinha, M. Milliron, Y.-W. Chu, V. Kapoor, R. E. Gress, E. Thomas, and C. L. Mackall (2004)
Blood 104, 2794-2800
 |  Abstract »  |  Full Text »  |  PDF »

Perturbed Homeostasis of Peripheral T Cells Elicits Decreased Susceptibility to Anti-CD3-Induced Apoptosis in Prediabetic Nonobese Diabetic Mice.

W. Yang, S. Hussain, Q.-S. Mi, P. Santamaria, and T. L. Delovitch (2004)
J. Immunol. 173, 4407-4416
 |  Abstract »  |  Full Text »  |  PDF »

CpG-matured Murine Plasmacytoid Dendritic Cells Are Capable of In Vivo Priming of Functional CD8 T Cell Responses to Endogenous but Not Exogenous Antigens.

M. Salio, M. J. Palmowski, A. Atzberger, I. F. Hermans, and V. Cerundolo (2004)
J. Exp. Med. 199, 567-579
 |  Abstract »  |  Full Text »  |  PDF »

In Vivo Expansion of the Residual Tumor Antigen-Specific CD8+ T Lymphocytes That Survive Negative Selection in Simian Virus 40 T-Antigen-Transgenic Mice.

T. D. Schell (2004)
J. Virol. 78, 1751-1762
 |  Abstract »  |  Full Text »  |  PDF »

A Role for TCR Affinity in Regulating Naive T Cell Homeostasis.

W. C. Kieper, J. T. Burghardt, and C. D. Surh (2004)
J. Immunol. 172, 40-44
 |  Abstract »  |  Full Text »  |  PDF »

IL-2 Is Not Required for the Initiation of CD8 T Cell Cycling but Sustains Expansion.

W. N. D'Souza and L. Lefrancois (2003)
J. Immunol. 171, 5727-5735
 |  Abstract »  |  Full Text »  |  PDF »

Immunomodulation in Established Murine Tumors: Response and Survival Rate Enhancement by Blood Leukocyte-Augmenting Substance 236 (Cl-), a Novel Synthetic Compound.

S. P. Cuadrado, M. d. C. Moreno Koch, C. F. Perez, L. M. Castejon Castan, C. P. Villalobos, M. J. Gonzalez Mateos, and C. L. Olmos (2003)
Clin. Cancer Res. 9, 5776-5785
 |  Abstract »  |  Full Text »  |  PDF »

CC Chemokine Ligand 2 and Its Receptor Regulate Mucosal Production of IL-12 and TGF-{beta} in High Dose Oral Tolerance.

R. W. DePaolo, B. J. Rollins, W. Kuziel, and W. J. Karpus (2003)
J. Immunol. 171, 3560-3567
 |  Abstract »  |  Full Text »  |  PDF »

Dynamics of Suppressor T Cells: In Vivo Veritas.

H. von Boehmer (2003)
J. Exp. Med. 198, 845-849
 |  Full Text »  |  PDF »

Chronic Exposure to Low Levels of Antigen in the Periphery Causes Reversible Functional Impairment Correlating with Changes in CD5 Levels in Monoclonal CD8 T Cells.

P. Stamou, J. de Jersey, D. Carmignac, C. Mamalaki, D. Kioussis, and B. Stockinger (2003)
J. Immunol. 171, 1278-1284
 |  Abstract »  |  Full Text »  |  PDF »

Signal 3 Determines Tolerance versus Full Activation of Naive CD8 T Cells: Dissociating Proliferation and Development of Effector Function.

J. M. Curtsinger, D. C. Lins, and M. F. Mescher (2003)
J. Exp. Med. 197, 1141-1151
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of Avidity for Major Histocompatibility Complex in Homeostasis of Naive and Memory T Cells.

G. Kassiotis, R. Zamoyska, and B. Stockinger (2003)
J. Exp. Med. 197, 1007-1016
 |  Abstract »  |  Full Text »  |  PDF »

CD4+ T Cells Pass Through an Effector Phase During the Process of In Vivo Tolerance Induction.

C.-T. Huang, D. L. Huso, Z. Lu, T. Wang, G. Zhou, E. P. Kennedy, C. G. Drake, D. J. Morgan, L. A. Sherman, A. D. Higgins, et al. (2003)
J. Immunol. 170, 3945-3953
 |  Abstract »  |  Full Text »  |  PDF »

Self-Specific MHC Class II-Restricted CD4-CD8- T Cells That Escape Deletion and Lack Regulatory Activity.

C. Viret and C. A. Janeway Jr. (2003)
J. Immunol. 170, 201-209
 |  Abstract »  |  Full Text »  |  PDF »

The Hematologist and Radiation Casualties.

N. Dainiak, J. K. Waselenko, J. O. Armitage, T. J. MacVittie, and A. M. Farese (2003)
Hematology 2003, 473-496
 |  Abstract »  |  Full Text »  |  PDF »

The Balance Between Donor T Cell Anergy and Suppression Versus Lethal Graft-Versus-Host Disease Is Determined by Host Conditioning.

M. Gonzalez, S. A. Quezada, B. R. Blazar, A. Panoskaltsis-Mortari, A. Y. Rudensky, and R. J. Noelle (2002)
J. Immunol. 169, 5581-5589
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Costimulation Pathway Via the 4C8 Antigen for the Induction of CD4+ Regulatory T Cells.

J.-i. Masuyama, S. Kaga, S. Kano, and S. Minota (2002)
J. Immunol. 169, 3710-3716
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin 7 worsens graft-versus-host disease.

M. L. Sinha, T. J. Fry, D. H. Fowler, G. Miller, and C. L. Mackall (2002)
Blood 100, 2642-2649
 |  Abstract »  |  Full Text »  |  PDF »

Development of CD25+ T cells secreting transforming growth factor-{beta}1 by altered peptide ligands expressed as self-antigens.

H. Yamashiro, N. Hozumi, and N. Nakano (2002)
Int. Immunol. 14, 857-865
 |  Abstract »  |  Full Text »  |  PDF »

Thymic and Extrathymic T Cell Development Pathways Follow Different Rules.

R. Terra, N. Labrecque, and C. Perreault (2002)
J. Immunol. 169, 684-692
 |  Abstract »  |  Full Text »  |  PDF »

CD4 Cell Priming and Tolerization Are Differentially Programmed by APCs upon Initial Engagement.

A. D. Higgins, M. A. Mihalyo, P. W. McGary, and A. J. Adler (2002)
J. Immunol. 168, 5573-5581
 |  Abstract »  |  Full Text »  |  PDF »

CD40 Ligation in the Presence of Self-Reactive CD8 T Cells Leads to Severe Immunopathology.

E. Roth, J. Schwartzkopff, and H. Pircher (2002)
J. Immunol. 168, 5124-5129
 |  Abstract »  |  Full Text »  |  PDF »

Interleukin-7: from bench to clinic.

T. J. Fry and C. L. Mackall (2002)
Blood 99, 3892-3904
 |  Full Text »  |  PDF »

Positive Effects of Glucocorticoids on T Cell Function by Up-Regulation of IL-7 Receptor {alpha}.

D. Franchimont, J. Galon, M. S. Vacchio, S. Fan, R. Visconti, D. M. Frucht, V. Geenen, G. P. Chrousos, J. D. Ashwell, and J. J. O'Shea (2002)
J. Immunol. 168, 2212-2218
 |  Abstract »  |  Full Text »  |  PDF »

Peripheral Tolerance to a Nuclear Autoantigen: Dendritic Cells Expressing a Nuclear Autoantigen Lead to Persistent Anergic State of CD4+ Autoreactive T Cells After Proliferation.

K. Kawahata, Y. Misaki, M. Yamauchi, S. Tsunekawa, K. Setoguchi, J.-i. Miyazaki, and K. Yamamoto (2002)
J. Immunol. 168, 1103-1112
 |  Abstract »  |  Full Text »  |  PDF »

Can the Low-Avidity Self-Specific T Cell Repertoire Be Exploited for Tumor Rejection?.

T. A. Cordaro, K. E. de Visser, F. H. Tirion, T. N. M. Schumacher, and A. M. Kruisbeek (2002)
J. Immunol. 168, 651-660
 |  Abstract »  |  Full Text »  |  PDF »

CD8+ T Lymphocytes in Double {alpha}{beta} TCR Transgenic Mice. II. Competitive Fitness of Dual {alpha}{beta} TCR CD8+ T Lymphocytes in the Peripheral Pools.

N. Legrand and A. A. Freitas (2001)
J. Immunol. 167, 6158-6164
 |  Abstract »  |  Full Text »  |  PDF »

TCR/Self-Antigen Interactions Drive Double-Negative T Cell Peripheral Expansion and Differentiation into Suppressor Cells.

J. J. Priatel, O. Utting, and H.-S. Teh (2001)
J. Immunol. 167, 6188-6194
 |  Abstract »  |  Full Text »  |  PDF »

Neonatal thymectomy identifies two major pools of sessile and recirculating peripheral T cells which appear to be under separate homeostatic control.

C. P. Cunningham, W. G. Kimpton, A. Fernando, and R. N. P. Cahill (2001)
Int. Immunol. 13, 1351-1359
 |  Abstract »  |  Full Text »  |  PDF »

Antigen-Specific Modulation of an Immune Response by In Vivo Administration of Soluble MHC Class I Tetramers.

R. Maile, B. Wang, W. Schooler, A. Meyer, E. J. Collins, and J. A. Frelinger (2001)
J. Immunol. 167, 3708-3714
 |  Abstract »  |  Full Text »  |  PDF »

Phenotypic and Functional Analysis of CD8+ T Cells Undergoing Peripheral Deletion in Response to Cross-Presentation of Self-Antigen.

J. Hernandez, S. Aung, W. L. Redmond, and L. A. Sherman (2001)
J. Exp. Med. 194, 707-718
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Homeostasis: Thymus Regeneration and Peripheral T Cell Restoration in Mice with a Reduced Fraction of Competent Precursors.

A. R.M. Almeida, J. A.M. Borghans, and A. A. Freitas (2001)
J. Exp. Med. 194, 591-600
 |  Abstract »  |  Full Text »  |  PDF »

Adaptive Tolerance of CD4+ T Cells In Vivo: Multiple Thresholds in Response to a Constant Level of Antigen Presentation.

C. Tanchot, D. L. Barber, L. Chiodetti, and R. H. Schwartz (2001)
J. Immunol. 167, 2030-2039
 |  Abstract »  |  Full Text »  |  PDF »

Progress in cancer vaccines by enhanced self-presentation.

S. R. Riddell (2001)
PNAS 98, 8933-8935
 |  Full Text »  |  PDF »

Attrition of Bystander CD8 T Cells during Virus-Induced T-Cell and Interferon Responses.

J. M. McNally, C. C. Zarozinski, M.-Y. Lin, M. A. Brehm, H. D. Chen, and R. M. Welsh (2001)
J. Virol. 75, 5965-5976
 |  Abstract »  |  Full Text »  |  PDF »

Tolerance to Cyclosporin A-Induced Autologous Graft-Versus-Host Disease Is Mediated by a CD4+CD25+ Subset of Recent Thymic Emigrants.

D. Y. Wu and I. Goldschneider (2001)
J. Immunol. 166, 7158-7164
 |  Abstract »  |  Full Text »  |  PDF »

Ex Vivo Isolation and Characterization of CD4+CD25+ T Cells with Regulatory Properties from Human Blood.

D. Dieckmann, H. Plottner, S. Berchtold, T. Berger, and G. Schuler (2001)
J. Exp. Med. 193, 1303-1310
 |  Abstract »  |  Full Text »  |  PDF »

A potential role for interleukin-7 in T-cell homeostasis.

T. J. Fry, E. Connick, J. Falloon, M. M. Lederman, D. J. Liewehr, J. Spritzler, S. M. Steinberg, L. V. Wood, R. Yarchoan, J. Zuckerman, et al. (2001)
Blood 97, 2983-2990
 |  Abstract »  |  Full Text »  |  PDF »

Adoptive Transfer Enables Tumor Rejection Targeted against a Self-Antigen without the Induction of Autoimmunity.

S. C. Eck and L. A. Turka (2001)
Cancer Res. 61, 3077-3083
 |  Abstract »  |  Full Text »

Interleukin-7 restores immunity in athymic T-cell-depleted hosts.

T. J. Fry, B. L. Christensen, K. L. Komschlies, R. E. Gress, and C. L. Mackall (2001)
Blood 97, 1525-1533
 |  Abstract »  |  Full Text »  |  PDF »

IL-7 increases both thymic-dependent and thymic-independent T-cell regeneration after bone marrow transplantation.

C. L. Mackall, T. J. Fry, C. Bare, P. Morgan, A. Galbraith, and R. E. Gress (2001)
Blood 97, 1491-1497
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Fas-L-Expressing Apoptotic T Lymphocytes in Normal Human Peripheral Blood : In Vivo Suicide.

G. De Panfilis, A. Caruso, P. Sansoni, G. Pasolini, D. Semenza, and C. Torresani (2001)
Am. J. Pathol. 158, 387-391
 |  Abstract »  |  Full Text »  |  PDF »

Differentiation of T Regulatory Cells by Immature Dendritic Cells.

M.-G. Roncarolo, M. K. Levings, and C. Traversari (2001)
J. Exp. Med. 193, F5-F10
 |  Full Text »  |  PDF »

Immortalized Myeloid Suppressor Cells Trigger Apoptosis in Antigen-Activated T Lymphocytes.

E. Apolloni, V. Bronte, A. Mazzoni, P. Serafini, A. Cabrelle, D. M. Segal, H. A. Young, and P. Zanovello (2000)
J. Immunol. 165, 6723-6730
 |  Abstract »  |  Full Text »  |  PDF »

HSP70 from Trypanosoma cruzi is endowed with specific cell proliferation potential leading to apoptosis.

C. Maranon, L. Planelles, C. Alonso, and M. C. Lopez (2000)
Int. Immunol. 12, 1685-1693
 |  Abstract »  |  Full Text »  |  PDF »

Differential Survival of Naive CD4 and CD8 T Cells.

C. Ferreira, T. Barthlott, S. Garcia, R. Zamoyska, and B. Stockinger (2000)
J. Immunol. 165, 3689-3694
 |  Abstract »  |  Full Text »  |  PDF »

Survival and Homeostatic Proliferation of Naive Peripheral CD4+ T Cells in the Absence of Self Peptide:MHC Complexes.

S. R. M. Clarke and A. Y. Rudensky (2000)
J. Immunol. 165, 2458-2464
 |  Abstract »  |  Full Text »  |  PDF »

Homeostatic T Cell Proliferation: How Far Can T Cells Be Activated to Self-Ligands?.

C. D. Surh and J. Sprent (2000)
J. Exp. Med. 192, F9-F14
 |  Full Text »  |  PDF »

Coupling of Peripheral Tolerance to Endogenous Interleukin 10 Promotes Effective Modulation of Myelin-activated T Cells and Ameliorates Experimental Allergic Encephalomyelitis.

K. L. Legge, B. Min, J. J. Bell, J. C. Caprio, L. Li, R. K. Gregg, and H. Zaghouani (2000)
J. Exp. Med. 191, 2039-2052
 |  Abstract »  |  Full Text »  |  PDF »

Blockade of CD86 and CD40 induces alloantigen-specific immunoregulatory T cells that remain anergic even after reversal of hyporesponsiveness.

H. J. P. M. Koenen and I. Joosten (2000)
Blood 95, 3153-3161
 |  Abstract »  |  Full Text »  |  PDF »

Bystander Sensitization to Activation-Induced Cell Death as a Mechanism of Virus-Induced Immune Suppression.

C. C. Zarozinski, J. M. McNally, B. L. Lohman, K. A. Daniels, and R. M. Welsh (2000)
J. Virol. 74, 3650-3658
 |  Abstract »  |  Full Text »

Regulation of Lymphoid Homeostasis by IL-2 Receptor Signals In Vivo.

D. T. M. Leung, S. Morefield, and D. M. Willerford (2000)
J. Immunol. 164, 3527-3534
 |  Abstract »  |  Full Text »  |  PDF »

A Population of In Vivo Anergized T Cells with a Lower Activation Threshold for the Induction of CD25 Exhibit Differential Requirements in Mobilization of Intracellular Calcium and Mitogen-Activated Protein Kinase Activation.

O. Utting, S.-J. Teh, and H.-S. Teh (2000)
J. Immunol. 164, 2881-2889
 |  Abstract »  |  Full Text »  |  PDF »

A Role for E2F1 in the Induction of Apoptosis during Thymic Negative Selection.

I. García, M. Murga, A. Vicario, S. J. Field, and A. M. Zubiaga (2000)
Cell Growth Differ. 11, 91-98
 |  Abstract »  |  Full Text »

The Use of HLA A2.1/p53 Peptide Tetramers to Visualize the Impact of Self Tolerance on the TCR Repertoire.

J. Hernandez, P. P. Lee, M. M. Davis, and L. A. Sherman (2000)
J. Immunol. 164, 596-602
 |  Abstract »  |  Full Text »  |  PDF »

In Vivo CD4+ T Cell Tolerance Induction Versus Priming Is Independent of the Rate and Number of Cell Divisions.

A. J. Adler, C.-T. Huang, G. S. Yochum, D. W. Marsh, and D. M. Pardoll (2000)
J. Immunol. 164, 649-655
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of CD8+ T Lymphocytes That Persist After Peripheral Tolerance to a Self Antigen Expressed in the Pancreas.

C. T. Nugent, D. J. Morgan, J. A. Biggs, A. Ko, I. M. Pilip, E. G. Pamer, and L. A. Sherman (2000)
J. Immunol. 164, 191-200
 |  Abstract »  |  Full Text »  |  PDF »

Treatment of Allograft Recipients with Donor-Specific Transfusion and Anti-CD154 Antibody Leads to Deletion of Alloreactive CD8+ T Cells and Prolonged Graft Survival in a CTLA4-Dependent Manner.

N. N. Iwakoshi, J. P. Mordes, T. G. Markees, N. E. Phillips, A. A. Rossini, and D. L. Greiner (2000)
J. Immunol. 164, 512-521
 |  Abstract »  |  Full Text »  |  PDF »

Reconstitution of T-cell receptor repertoire diversity following T-cell depleted allogeneic bone marrow transplantation is related to hematopoietic chimerism.

C. J. Wu, A. Chillemi, E. P. Alyea, E. Orsini, D. Neuberg, R. J. Soiffer, and J. Ritz (2000)
Blood 95, 352-359
 |  Abstract »  |  Full Text »  |  PDF »

Cyclin D3 Regulates Proliferation and Apoptosis of Leukemic T Cell Lines.

G. J. J. C. Boonen, B. A. van Oirschot, A. van Diepen, W. J. M. Mackus, L. F. Verdonck, G. Rijksen, and R. H. Medema (1999)
J. Biol. Chem. 274, 34676-34682
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Receptor-induced Activation and Apoptosis In Cycling Human T Cells Occur throughout the Cell Cycle.

M. Karas, T. Z. Zaks, L. JL, and D. LeRoith (1999)
Mol. Biol. Cell 10, 4441-4450
 |  Abstract »  |  Full Text »

CD4+ CD45RB Low-Density Cells from Untreated Mice Prevent Acute Allograft Rejection.

J. D. Davies, E. O'Connor, D. Hall, T. Krahl, J. Trotter, and N. Sarvetnick (1999)
J. Immunol. 163, 5353-5357
 |  Abstract »  |  Full Text »  |  PDF »

Homeostatic expansion and phenotypic conversion of naive T cells in response to self peptide/MHC ligands.

W. C. Kieper and S. C. Jameson (1999)
PNAS 96, 13306-13311
 |  Abstract »  |  Full Text »  |  PDF »

Long-term persistence of IL-2-unresponsive allogeneic T cells in sublethally irradiated SCID mice.

D. Spaner, X. Sheng-Tanner, K. Raju, B. Rabinovich, H. Messner, and R. G. Miller (1999)
Int. Immunol. 11, 1601-1614
 |  Abstract »  |  Full Text »  |  PDF »

CD4+ T Cell Division in Irradiated Mice Requires Peptides Distinct from Those Responsible for Thymic Selection.

J. Bender, T. Mitchell, J. Kappler, and P. Marrack (1999)
J. Exp. Med. 190, 367-374
 |  Abstract »  |  Full Text »  |  PDF »

On the Lifespan of Virgin T Lymphocytes.

F. Di Rosa, S. Ramaswamy, J. P. Ridge, and P. Matzinger (1999)
J. Immunol. 163, 1253-1257
 |  Abstract »  |  Full Text »  |  PDF »

On the role of thymic epithelium vs. bone marrow-derived cells in repertoire selection of T cells.

R. M. Zinkernagel and A. Althage (1999)
PNAS 96, 8092-8097
 |  Abstract »  |  Full Text »  |  PDF »

Cytotoxic T-Lymphocyte Epitope Immunodominance in the Control of Choroid Plexus Tumors in Simian Virus 40 Large T Antigen Transgenic Mice.

T. D. Schell, L. M. Mylin, I. Georgoff, A. K. Teresky, A. J. Levine, and S. S. Tevethia (1999)
J. Virol. 73, 5981-5993
 |  Abstract »  |  Full Text »

CD8+ T Cells Become Nonresponsive (Anergic) Following Activation in the Presence of Costimulation.

M. J. Deeths, R. M. Kedl, and M. F. Mescher (1999)
J. Immunol. 163, 102-110
 |  Abstract »  |  Full Text »  |  PDF »

Anergic CD8+ T Cells Can Persist and Function In Vivo.

C. A. Blish, S. R. Dillon, A. G. Farr, and P. J. Fink (1999)
J. Immunol. 163, 155-164
 |  Abstract »  |  Full Text »  |  PDF »

Altered Expression Level of a Systemic Nuclear Autoantigen Determines the Fate of Immune Response to Self.

K. Kawahata, Y. Misaki, Y. Komagata, K. Setoguchi, S. Tsunekawa, Y. Yoshikawa, J.-i. Miyazaki, and K. Yamamoto (1999)
J. Immunol. 162, 6482-6491
 |  Abstract »  |  Full Text »  |  PDF »

To Advertise   |   Find Products