Science 22 February 1991: Vol. 251. no. 4996, pp. 942 - 944 DOI: 10.1126/science.2000495

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Articles

Conductance of Connexin Hemichannels Segregates with the First Transmembrane Segment.

X. Hu, M. Ma, and G. Dahl (2006)
Biophys. J. 90, 140-150
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Overview of Molecular Relationships in the Voltage-Gated Ion Channel Superfamily.

F. H. Yu, V. Yarov-Yarovoy, G. A. Gutman, and W. A. Catterall (2005)
Pharmacol. Rev. 57, 387-395
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Domain analysis of Kv6.3, an electrically silent channel.

N. Ottschytsch, A. L Raes, J.-P. Timmermans, and D. J Snyders (2005)
J. Physiol. 568, 737-747
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Rapid Intracellular TEA Block of the KcsA Potassium Channel.

E. Kutluay, B. Roux, and L. Heginbotham (2005)
Biophys. J. 88, 1018-1029
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The VGL-Chanome: A Protein Superfamily Specialized for Electrical Signaling and Ionic Homeostasis.

F. H. Yu and W. A. Catterall (2004)
Sci. STKE 2004, re15
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Functional Analysis of Caenorhabditis elegans Glutamate Receptor Subunits by Domain Transplantation.

N. Strutz-Seebohm, M. Werner, D. M. Madsen, G. Seebohm, Y. Zheng, C. S. Walker, A. V. Maricq, and M. Hollmann (2003)
J. Biol. Chem. 278, 44691-44701
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Voltage-Gated K Channels.

C. M. Armstrong (2003)
Sci. STKE 2003, re10
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Modeling Permeation Energetics in the KcsA Potassium Channel.

S. Garofoli and P. C. Jordan (2003)
Biophys. J. 84, 2814-2830
 |  Abstract »  |  Full Text »  |  PDF »

Sequence-Function Analysis of the K+-Selective Family of Ion Channels Using a Comprehensive Alignment and the KcsA Channel Structure.

R. T. Shealy, A. D. Murphy, R. Ramarathnam, E. Jakobsson, and S. Subramaniam (2003)
Biophys. J. 84, 2929-2942
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Control of Ion Conduction in L-type Ca2+ Channels by the Concerted Action of S5-6 Regions.

S. M. Cibulsky and W. A. Sather (2003)
Biophys. J. 84, 1709-1719
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Influence of Pore Residues on Permeation Properties in the Kv2.1 Potassium Channel. Evidence for a Selective Functional Interaction of K+ with the Outer Vestibule.

J. F. Consiglio, P. Andalib, and S. J. Korn (2003)
J. Gen. Physiol. 121, 111-124
 |  Abstract »  |  Full Text »  |  PDF »

Noncontact Dipole Effects on Channel Permeation. VI. 5F- and 6F-Trp Gramicidin Channel Currents.

C. D. Cole, A. S. Frost, N. Thompson, M. Cotten, T. A. Cross, and D. D. Busath (2002)
Biophys. J. 83, 1974-1986
 |  Abstract »  |  Full Text »  |  PDF »

Site-directed Glycosylation Tagging of Functional Kir2.1 Reveals That the Putative Pore-forming Segment Is Extracellular.

R. A. Schwalbe, A. Rudin, S.-L. Xia, and C. S. Wingo (2002)
J. Biol. Chem. 277, 24382-24389
 |  Abstract »  |  Full Text »  |  PDF »

Distinct K Currents Result in Physiologically Distinct Cell Types in the Inferior Colliculus of the Rat.

S. Sivaramakrishnan and D. L. Oliver (2001)
J. Neurosci. 21, 2861-2877
 |  Abstract »  |  Full Text »  |  PDF »

Heterogeneity of Kv2.1 mRNA Expression and Delayed Rectifier Current in Single Isolated Myocytes From Rat Left Ventricle.

J.-H. Schultz, T. Volk, and H. Ehmke (2001)
Circ. Res. 88, 483-490
 |  Abstract »  |  Full Text »  |  PDF »

Potassium Channels: Molecular Defects, Diseases, and Therapeutic Opportunities.

C.-C. Shieh, M. Coghlan, J. P. Sullivan, and M. Gopalakrishnan (2000)
Pharmacol. Rev. 52, 557-594
 |  Abstract »  |  Full Text »  |  PDF »

Close Association of the N Terminus of Kv1.3 with the Pore Region.

X. Yao, W. Liu, S. Tian, H. Rafi, A. S. Segal, and G. V. Desir (2000)
J. Biol. Chem. 275, 10859-10863
 |  Abstract »  |  Full Text »  |  PDF »

Tertiapin Potently and Selectively Blocks Muscarinic K+ Channels in Rabbit Cardiac Myocytes.

H. Kitamura, M. Yokoyama, H. Akita, K. Matsushita, Y. Kurachi, and M. Yamada (2000)
J. Pharmacol. Exp. Ther. 293, 196-205
 |  Abstract »  |  Full Text »

The Accessibility of a Novel Reentrant Loop of the Glutamate Transporter GLT-1 Is Restricted by Its Substrate.

M. Grunewald and B. I. Kanner (2000)
J. Biol. Chem. 275, 9684-9689
 |  Abstract »  |  Full Text »  |  PDF »

Charged residues in the M2 region of alpha -hENaC play a role in channel conductance.

A. L. B. Langloh, B. Berdiev, H.-L. Ji, K. Keyser, B. A. Stanton, and D. J. Benos (2000)
Am J Physiol Cell Physiol 278, C277-C291
 |  Abstract »  |  Full Text »  |  PDF »

Ultrafast Inactivation Causes Inward Rectification in a Voltage-Gated K+ Channel from Caenorhabditis elegans.

R. Fleischhauer, M. W. Davis, I. Dzhura, A. Neely, L. Avery, and R. H. Joho (2000)
J. Neurosci. 20, 511-520
 |  Abstract »  |  Full Text »  |  PDF »

Structure and Dynamics of the Pore of Inwardly Rectifying KATP Channels.

G. Loussouarn, E. N. Makhina, T. Rose, and C. G. Nichols (2000)
J. Biol. Chem. 275, 1137-1144
 |  Abstract »  |  Full Text »  |  PDF »

Cloning of Components of a Novel Subthreshold-Activating K+ Channel with a Unique Pattern of Expression in the Cerebral Cortex.

M. J. Saganich, E. V.-S. de Miera, M. S. Nadal, H. Baker, W. A. Coetzee, and B. Rudy (1999)
J. Neurosci. 19, 10789-10802
 |  Abstract »  |  Full Text »  |  PDF »

Cloning and Functional Expression of Novel N-type Ca2+ Channel Variants.

Q. Lu and K. Dunlap (1999)
J. Biol. Chem. 274, 34566-34575
 |  Abstract »  |  Full Text »  |  PDF »

Different State Dependencies of 4-Aminopyridine Binding to rKv1.4 and rKv4.2: Role of the Cytoplasmic Halves of the Fifth and Sixth Transmembrane Segments.

G.-N. Tseng (1999)
J. Pharmacol. Exp. Ther. 290, 569-577
 |  Abstract »  |  Full Text »

Structure and function of the cardiac sodium channels.

J. R. Balser (1999)
Cardiovasc Res 42, 327-328
 |  Abstract »  |  Full Text »  |  PDF »

Identification by Differential Display of a Hypertonicity-inducible Inward Rectifier Potassium Channel Highly Expressed in Chloride Cells.

Y. Suzuki, M. Itakura, M. Kashiwagi, N. Nakamura, T. Matsuki, H. Sakuta, N. Naito, K. Takano, T. Fujita, and S. Hirose (1999)
J. Biol. Chem. 274, 11376-11382
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Identification of structural elements of the testis-specific voltage dependent calcium channel that potentially regulate its biophysical properties.

L. O. Goodwin, N. B. Leeds, D. Guzowski, I. R. Hurley, R. G. Pergolizzi, and S. Benoff (1999)
Mol. Hum. Reprod. 5, 311-322
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Genetic Selection of Mutations in the High Affinity K+ Transporter HKT1 That Define Functions of a Loop Site for Reduced Na+ Permeability and Increased Na+ Tolerance.

F. Rubio, M. Schwarz, W. Gassmann, and J. I. Schroeder (1999)
J. Biol. Chem. 274, 6839-6847
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The Epithelial Inward Rectifier Channel Kir7.1 Displays Unusual K+ Permeation Properties.

F. Doring, C. Derst, E. Wischmeyer, C. Karschin, R. Schneggenburger, J. Daut, and A. Karschin (1998)
J. Neurosci. 18, 8625-8636
 |  Abstract »  |  Full Text »  |  PDF »

Subunit Folding and Assembly Steps Are Interspersed during Shaker Potassium Channel Biogenesis.

C. T. Schulteis, N. Nagaya, and D. M. Papazian (1998)
J. Biol. Chem. 273, 26210-26217
 |  Abstract »  |  Full Text »  |  PDF »

Slo3, a Novel pH-sensitive K+ Channel from Mammalian Spermatocytes.

M. Schreiber, A. Wei, A. Yuan, J. Gaut, M. Saito, and L. Salkoff (1998)
J. Biol. Chem. 273, 3509-3516
 |  Abstract »  |  Full Text »  |  PDF »

Alternative Splicing in the Pore-Forming Region of shaker Potassium Channels.

M. Kim, D. J. Baro, C. C. Lanning, M. Doshi, J. Farnham, H. S. Moskowitz, J. H. Peck, B. M. Olivera, and R. M. Harris-Warrick (1997)
J. Neurosci. 17, 8213-8224
 |  Abstract »  |  Full Text »  |  PDF »

Mapping the Kidney Potassium Channel ROMK1. GLYCOSYLATION OF THE PORE SIGNATURE SEQUENCE AND THE COOH TERMINUS.

R. A. Schwalbe, L. Bianchi, and A. M. Brown (1997)
J. Biol. Chem. 272, 25217-25223
 |  Abstract »  |  Full Text »  |  PDF »

Topology of the Shaker Potassium Channel Probed with Hydrophilic Epitope Insertions.

T. M. Shih and A. L. Goldin (1997)
J. Cell Biol. 136, 1037-1045
 |  Abstract »  |  Full Text »  |  PDF »

A Novel Subunit for Shal K+ Channels Radically Alters Activation and Inactivation.

T. Jegla and L. Salkoff (1997)
J. Neurosci. 17, 32-44
 |  Abstract »  |  Full Text »  |  PDF »

Expression and Function of Pancreatic beta -Cell Delayed Rectifier K+ Channels. ROLE IN STIMULUS-SECRETION COUPLING.

M. Wm. Roe, J. F. Worley III, A. A. Mittal, A. Kuznetsov, S. DasGupta, R. J. Mertz, S. M. Witherspoon III, N. Blair, M. E. Lancaster, M. S. McIntyre, et al. (1996)
J. Biol. Chem. 271, 32241-32246
 |  Abstract »  |  Full Text »  |  PDF »

Novel Sites of N-Glycosylation in ROMK1 Reveal the Putative Pore-forming Segment H5 as Extracellular.

R. A. Schwalbe, Z. Wang, L. Bianchi, and A. M. Brown (1996)
J. Biol. Chem. 271, 24201-24206
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Analysis of a Binding Site for Quinidine in a Human Cardiac Delayed Rectifier K+ Channel : Role of S6 in Antiarrhythmic Drug Binding.

S. W. Yeola, T. C. Rich, V. N. Uebele, M. M. Tamkun, and D. J. Snyders (1996)
Circ. Res. 78, 1105-1114
 |  Abstract »  |  Full Text »

Silver as a probe of pore-forming residues in a potassium channel.

Q Lu and C Miller (1995)
Science 268, 304-307
 |  Abstract »  |  PDF »

Revealing the architecture of a K+ channel pore through mutant cycles with a peptide inhibitor.

P Hidalgo and R MacKinnon (1995)
Science 268, 307-310
 |  Abstract »  |  PDF »

A Topological Analysis of Goldfish Kainate Receptors Predicts Three Transmembrane Segments.

Z. G. Wo and R. E. Oswald (1995)
J. Biol. Chem. 270, 2000-2009
 |  Abstract »  |  Full Text »  |  PDF »

Specification of pore properties by the carboxyl terminus of inwardly rectifying K+ channels.

M Taglialatela, B. Wible, R Caporaso, and A. Brown (1994)
Science 264, 844-847
 |  Abstract »  |  PDF »

Expression of an inward-rectifying potassium channel by the Arabidopsis KAT1 cDNA.

D. Schachtman, J. Schroeder, W. Lucas, J. Anderson, and R. Gaber (1992)
Science 258, 1654-1658
 |  Abstract »  |  PDF »

A functional connection between the pores of distantly related ion channels as revealed by mutant K+ channels.

L Heginbotham, T Abramson, and R MacKinnon (1992)
Science 258, 1152-1155
 |  Abstract »  |  PDF »

Acetylcholine receptor channel structure probed in cysteine-substitution mutants.

M. Akabas, D. Stauffer, M Xu, and A Karlin (1992)
Science 258, 307-310
 |  Abstract »  |  PDF »

Specification of subunit assembly by the hydrophilic amino-terminal domain of the Shaker potassium channel.

M Li, Y. Jan, and L. Jan (1992)
Science 257, 1225-1230
 |  Abstract »  |  PDF »

Molecular localization of an ion-binding site within the pore of mammalian sodium channels.

P. Backx, D. Yue, J. Lawrence, E Marban, and G. Tomaselli (1992)
Science 257, 248-251
 |  Abstract »  |  PDF »

Similarities in amino acid sequences of Drosophila eag and cyclic nucleotide-gated channels.

H. Guy, Durell SR, J Warmke, R Drysdale, and B Ganetzky (1991)
Science 254, 730
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A component of calcium-activated potassium channels encoded by the Drosophila slo locus.

N. Atkinson, G. Robertson, and B Ganetzky (1991)
Science 253, 551-555
 |  Abstract »  |  PDF »

A distinct potassium channel polypeptide encoded by the Drosophila eag locus.

J Warmke, R Drysdale, and B Ganetzky (1991)
Science 252, 1560-1562
 |  Abstract »  |  PDF »

Flexibility of the Kir6.2 inward rectifier K+ channel pore.

G. Loussouarn, L. R. Phillips, R. Masia, T. Rose, and C. G. Nichols (2001)
PNAS 98, 4227-4232
 |  Abstract »  |  Full Text »  |  PDF »

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