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Science 22 February 1991:
Vol. 251. no. 4996, pp. 893 - 898
DOI: 10.1126/science.2000490
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Articles

Science, Vol 251, Issue 4996, 893-898
Copyright © 1991 by American Association for the Advancement of Science

articles

DNA: a model compound for solution studies of macromolecules

R Pecora

Stanford University, CA 94305-5080.

Well-defined, monodisperse, homologous series of oligonucleotides and DNA restriction fragments may now be produced and used as models of rigid and semirigid rodlike molecules in solution. Information from optical experiments on these model systems aids in the formulation and testing of theories of macromolecular dynamics in both dilute and concentrated solution.


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