Science 7 December 1990: Vol. 250. no. 4986, pp. 1400 - 1403 DOI: 10.1126/science.2147779

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Articles

Genomic Analysis Reveals Mycoplasma pneumoniae Repetitive Element 1-Mediated Recombination in a Clinical Isolate.

O. Musatovova, T. R. Kannan, and J. B. Baseman (2008)
Infect. Immun. 76, 1639-1648
 |  Abstract »  |  Full Text »  |  PDF »

Kaposi's Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 ORF50/Rta Lytic Switch Protein Functions as a Tetramer.

W. Bu, K. D. Carroll, D. Palmeri, and D. M. Lukac (2007)
J. Virol. 81, 5788-5806
 |  Abstract »  |  Full Text »  |  PDF »

A comparison of the DNA binding and bending capacities and the oligomeric states of the immunity repressors of heteroimmune coliphages P2 and W{Phi}.

A. Ahlgren-Berg, P. Henriksson-Peltola, W. Sehlen, and E. Haggard-Ljungquist (2007)
Nucleic Acids Res. 35, 3167-3180
 |  Abstract »  |  Full Text »  |  PDF »

Structural Basis for the Conformational Integrity of the Arabidopsis thaliana HY5 Leucine Zipper Homodimer.

M.-K. Yoon, H.-M. Kim, G. Choi, J.-O. Lee, and B.-S. Choi (2007)
J. Biol. Chem. 282, 12989-13002
 |  Abstract »  |  Full Text »  |  PDF »

Utilization of an Amphipathic Leucine Zipper Sequence to Design Antibacterial Peptides with Simultaneous Modulation of Toxic Activity against Human Red Blood Cells.

A. Ahmad, S. P. Yadav, N. Asthana, K. Mitra, S. P. Srivastava, and J. K. Ghosh (2006)
J. Biol. Chem. 281, 22029-22038
 |  Abstract »  |  Full Text »  |  PDF »

A ToxR-based two-hybrid system for the detection of periplasmic and cytoplasmic protein-protein interactions in Escherichia coli: minimal requirements for specific DNA binding and transcriptional activation.

F. Hennecke, A. Muller, R. Meister, A. Strelow, and S. Behrens (2005)
Protein Eng. Des. Sel. 18, 477-486
 |  Abstract »  |  Full Text »  |  PDF »

Novel mobilizable prokaryotic two-hybrid system vectors for high-throughput protein interaction mapping in Escherichia coli by bacterial conjugation.

P. Clarke, Pár. Cuív, and M. O'Connell (2005)
Nucleic Acids Res. 33, e18
 |  Abstract »  |  Full Text »  |  PDF »

p116Rip Targets Myosin Phosphatase to the Actin Cytoskeleton and Is Essential for RhoA/ROCK-regulated Neuritogenesis.

J. Mulder, A. Ariaens, D. van den Boomen, and W. H. Moolenaar (2004)
Mol. Biol. Cell 15, 5516-5527
 |  Abstract »  |  Full Text »  |  PDF »

A systematic method for identifying small-molecule modulators of protein-protein interactions.

A. R. Horswill, S. N. Savinov, and S. J. Benkovic (2004)
PNAS 101, 15591-15596
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Motifs Involved in Endoplasmic Reticulum Retention-Forward Trafficking of the GLT-1 Subtype of Glutamate Transporter.

A. Kalandadze, Y. Wu, K. Fournier, and M. B. Robinson (2004)
J. Neurosci. 24, 5183-5192
 |  Abstract »  |  Full Text »  |  PDF »

Dimerization of cGMP-dependent Protein Kinase I{beta} Is Mediated by an Extensive Amino-terminal Leucine Zipper Motif, and Dimerization Modulates Enzyme Function.

R. Richie-Jannetta, S. H. Francis, and J. D. Corbin (2003)
J. Biol. Chem. 278, 50070-50079
 |  Abstract »  |  Full Text »  |  PDF »

Interactions between the PTS Regulation domains of the BglG Transcriptional Antiterminator from Escherichia coli.

L. Fux, A. Nussbaum-Shochat, and O. Amster-Choder (2003)
J. Biol. Chem. 278, 46203-46209
 |  Abstract »  |  Full Text »  |  PDF »

A Heterologous Coiled Coil Can Substitute for Helix I of the Sindbis Virus Capsid Protein.

R. Perera, C. Navaratnarajah, and R. J. Kuhn (2003)
J. Virol. 77, 8345-8353
 |  Abstract »  |  Full Text »  |  PDF »

Sites of Interaction between the FecA and FecR Signal Transduction Proteins of Ferric Citrate Transport in Escherichia coli K-12.

S. Enz, H. Brand, C. Orellana, S. Mahren, and V. Braun (2003)
J. Bacteriol. 185, 3745-3752
 |  Abstract »  |  Full Text »  |  PDF »

Mutational Analysis Reveals a Role for the C Terminus of the Proteasome Subunit Rpt4p in Spindle Pole Body Duplication in Saccharomyces cerevisiae.

H. B. McDonald, A. H. Helfant, E. M. Mahony, S. K. Khosla, and L. Goetsch (2002)
Genetics 162, 705-720
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Dissection of VirB, a Key Regulator of the Virulence Cascade of Shigella flexneri.

C. Beloin, S. McKenna, and C. J. Dorman (2002)
J. Biol. Chem. 277, 15333-15344
 |  Abstract »  |  Full Text »  |  PDF »

Supramolecular Chemistry And Self-assembly Special Feature: Peptide-amphiphile nanofibers: A versatile scaffold for the preparation of self-assembling materials.

J. D. Hartgerink, E. Beniash, and S. I. Stupp (2002)
PNAS 99, 5133-5138
 |  Abstract »  |  Full Text »  |  PDF »

Evolutionary Implications of Three Novel Members of the Human Sarcomeric Myosin Heavy Chain Gene Family.

P. R. Desjardins, J. M. Burkman, J. B. Shrager, L. A. Allmond, and H. H. Stedman (2002)
Mol. Biol. Evol. 19, 375-393
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of the Dimerization Domain in the FNR Transcription Factor.

L. J. Moore and P. J. Kiley (2001)
J. Biol. Chem. 276, 45744-45750
 |  Abstract »  |  Full Text »  |  PDF »

Identification of the Domains of UreR, an AraC-Like Transcriptional Regulator of the Urease Gene Cluster in Proteus mirabilis.

C. A. Poore, C. Coker, J. D. Dattelbaum, and H. L. T. Mobley (2001)
J. Bacteriol. 183, 4526-4535
 |  Abstract »  |  Full Text »  |  PDF »

A two-hybrid system based on chimeric operator recognition for studying protein homo/heterodimerization in Escherichia coli.

G. Di Lallo, L. Castagnoli, P. Ghelardini, and L. Paolozzi (2001)
Microbiology 147, 1651-1656
 |  Abstract »  |  Full Text »  |  PDF »

Cnr interferes with dimerization of the replication protein {{alpha}} in phage-plasmid P4.

A. Tocchetti, S. Serina, I. Oliva, G. Deho, and D. Ghisotti (2001)
Nucleic Acids Res. 29, 536-544
 |  Abstract »  |  Full Text »  |  PDF »

The Multifunctional Bacteriophage P2 Cox Protein Requires Oligomerization for Biological Activity.

J. M. Eriksson and E. Haggård-Ljungquist (2000)
J. Bacteriol. 182, 6714-6723
 |  Abstract »  |  Full Text »

A guided tour in protein interaction space: Coiled coils from the yeast proteome.

J. C. Hu (2000)
PNAS 97, 12935-12936
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Characterization of bacteriophage T4-coordinated leading- and lagging-strand synthesis on a minicircle substrate.

F. Salinas and S. J. Benkovic (2000)
PNAS 97, 7196-7201
 |  Abstract »  |  Full Text »  |  PDF »

An Immunoglobulin Superfamily-Like Domain Unique to the Yersinia pseudotuberculosis Invasin Protein Is Required for Stimulation of Bacterial Uptake via Integrin Receptors.

P. Dersch and R. R. Isberg (2000)
Infect. Immun. 68, 2930-2938
 |  Abstract »  |  Full Text »  |  PDF »

The PspA Protein of Escherichia coli Is a Negative Regulator of sigma 54-Dependent Transcription.

J. Dworkin, G. Jovanovic, and P. Model (2000)
J. Bacteriol. 182, 311-319
 |  Abstract »  |  Full Text »

Patterned library analysis: A method for the quantitative assessment of hypotheses concerning the determinants of protein structure.

S. J. Lahr, A. Broadwater, C. W. Carter Jr., M. L. Collier, L. Hensley, J. C. Waldner, G. J. Pielak, and M. H. Edgell (1999)
PNAS 96, 14860-14865
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of alpha -Helical Coiled-coil Dimerization in Chicken Skeletal Muscle Light Meromyosin.

M. J. Arrizubieta and E. Bandman (1999)
J. Biol. Chem. 274, 13847-13853
 |  Abstract »  |  Full Text »  |  PDF »

The Hepatitis B pX Protein Promotes Dimerization and DNA Binding of Cellular Basic Region/Leucine Zipper Proteins by Targeting the Conserved Basic Region.

G. Perini, E. Oetjen, and M. R. Green (1999)
J. Biol. Chem. 274, 13970-13977
 |  Abstract »  |  Full Text »  |  PDF »

The Extracellular Domain of the Saccharomyces cerevisiae Sln1p Membrane Osmolarity Sensor Is Necessary for Kinase Activity.

D. B. Ostrander and J. A. Gorman (1999)
J. Bacteriol. 181, 2527-2534
 |  Abstract »  |  Full Text »

Unique DNA Binding Specificity of the Binuclear Zinc AlcR Activator of the Ethanol Utilization Pathway in Aspergillus nidulans.

I. Nikolaev, F. Lenouvel, and B. Felenbok (1999)
J. Biol. Chem. 274, 9795-9802
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of the Dimerization Domain in BglG, an RNA-Binding Transcriptional Antiterminator from Escherichia coli.

A. Boss, A. Nussbaum-Shochat, and O. Amster-Choder (1999)
J. Bacteriol. 181, 1755-1766
 |  Abstract »  |  Full Text »

MalK Forms a Dimer Independent of Its Assembly into the MalFGK2 ATP-binding Cassette Transporter of Escherichia coli.

K. A. Kennedy and B. Traxler (1999)
J. Biol. Chem. 274, 6259-6264
 |  Abstract »  |  Full Text »  |  PDF »

Functional dissection of the transmitter module of the histidine kinase NtrB in Escherichia coli.

G. Kramer and V. Weiss (1999)
PNAS 96, 604-609
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Double-Stranded RNA-Dependent Protein Kinase PKR by Vaccinia Virus E3: Role of Complex Formation and the E3 N-Terminal Domain.

P. R. Romano, F. Zhang, S.-L. Tan, M. T. Garcia-Barrio, M. G. Katze, T. E. Dever, and A. G. Hinnebusch (1998)
Mol. Cell. Biol. 18, 7304-7316
 |  Abstract »  |  Full Text »

An autonomous folding unit mediates the assembly of two-stranded coiled coils.

R. A. Kammerer, T. Schulthess, R. Landwehr, A. Lustig, J. Engel, U. Aebi, and M. O. Steinmetz (1998)
PNAS 95, 13419-13424
 |  Abstract »  |  Full Text »  |  PDF »

The Saccharomyces cerevisiae GATA Factors Dal80p and Deh1p Can Form Homo- and Heterodimeric Complexes.

V. V. Svetlov and T. G. Cooper (1998)
J. Bacteriol. 180, 5682-5688
 |  Abstract »  |  Full Text »

Multimer Formation Is Not Essential for Nuclear Export of Human T-Cell Leukemia Virus Type 1 Rex trans-Activator Protein.

P. Heger, O. Rosorius, C. Koch, G. Casari, R. Grassmann, and J. Hauber (1998)
J. Virol. 72, 8659-8668
 |  Abstract »  |  Full Text »  |  PDF »

Control of PKR Protein Kinase by Hepatitis C Virus Nonstructural 5A Protein: Molecular Mechanisms of Kinase Regulation.

M. Gale Jr., C. M. Blakely, B. Kwieciszewski, S.-L. Tan, M. Dossett, N. M. Tang, M. J. Korth, S. J. Polyak, D. R. Gretch, and M. G. Katze (1998)
Mol. Cell. Biol. 18, 5208-5218
 |  Abstract »  |  Full Text »

cAMP Response Element-binding Protein Monomers Cooperatively Assemble to Form Dimers on DNA.

X. Wu, C. Spiro, W. G. Owen, and C. T. McMurray (1998)
J. Biol. Chem. 273, 20820-20827
 |  Abstract »  |  Full Text »  |  PDF »

Double-Stranded RNA-Independent Dimerization of Interferon-Induced Protein Kinase PKR and Inhibition of Dimerization by the Cellular P58IPK Inhibitor.

S.-L. Tan, M. J. Gale Jr., and M. G. Katze (1998)
Mol. Cell. Biol. 18, 2431-2443
 |  Abstract »  |  Full Text »

A Leucine Zipper-Like Domain Is Essential for Dimerization and Encapsidation of Bluetongue Virus Nucleocapsid Protein VP4.

N. Ramadevi, J. Rodriguez, and P. Roy (1998)
J. Virol. 72, 2983-2990
 |  Abstract »  |  Full Text »  |  PDF »

The Regulator of Nitrate Assimilation in Ascomycetes Is a Dimer Which Binds a Nonrepeated, Asymmetrical Sequence.

J. Strauss, M. I. Muro-Pastor, and C. Scazzocchio (1998)
Mol. Cell. Biol. 18, 1339-1348
 |  Abstract »  |  Full Text »

PNZIP Is a Novel Mesophyll-Specific cDNA That Is Regulated by Phytochrome and a Circadian Rhythm and Encodes a Protein with a Leucine Zipper Motif.

C. Chao Zheng, R. Porat, P. Lu, and S. D. O' Neill (1998)
Plant Physiology 116, 27-35
 |  Abstract »  |  Full Text »

Overexpression of nreB, a New GATA Factor-encoding Gene of Penicillium chrysogenum, Leads to Repression of the Nitrate Assimilatory Gene Cluster.

H. Haas, K. Angermayr, I. Zadra, and G. Stoffler (1997)
J. Biol. Chem. 272, 22576-22582
 |  Abstract »  |  Full Text »  |  PDF »

The Zinc Binuclear Cluster Activator AlcR Is Able to Bind to Single Sites but Requires Multiple Repeated Sites for Synergistic Activation of the alcA Gene in Aspergillus nidulans.

C. Panozzo, V. Capuano, S. Fillinger, and B. Felenbok (1997)
J. Biol. Chem. 272, 22859-22865
 |  Abstract »  |  Full Text »  |  PDF »

In Vitro Recognition of Specific DNA Targets by AlcR, a Zinc Binuclear Cluster Activator Different from the Other Proteins of This Class.

F. Lenouvel, I. Nikolaev, and B. Felenbok (1997)
J. Biol. Chem. 272, 15521-15526
 |  Abstract »  |  Full Text »  |  PDF »

Buried asparagines determine the dimerization specificities of leucine zipper mutants.

X. Zeng, A. M. Herndon, and J. C. Hu (1997)
PNAS 94, 3673-3678
 |  Abstract »  |  Full Text »  |  PDF »

Caenorhabditis elegans LET-502 is related to Rho-binding kinases and human myotonic dystrophy kinase and interacts genetically with a homolog of the regulatory subunit of smooth muscle myosin phosphatase to affect cell shape..

A Wissmann, J Ingles, J D McGhee, and P E Mains (1997)
Genes & Dev. 11, 409-422
 |  Abstract »  |  PDF »

The Assembly of Human Fibrinogen. THE ROLE OF THE AMINO-TERMINAL AND COILED-COIL REGIONS OF THE THREE CHAINS IN THE FORMATION OF THE alpha gamma AND beta gamma HETERODIMERS AND alpha beta gamma HALF-MOLECULES.

W.-f. Xu, D. W. Chung, and E. W. Davie (1996)
J. Biol. Chem. 271, 27948-27953
 |  Abstract »  |  Full Text »  |  PDF »

Signal Detection by the PhoQ Sensor-Transmitter. CHARACTERIZATION OF THE SENSOR DOMAIN AND A RESPONSE-IMPAIRED MUTANT THAT IDENTIFIES LIGAND-BINDING DETERMINANTS.

C. D. Waldburger and R. T. Sauer (1996)
J. Biol. Chem. 271, 26630-26636
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Recombinant HLA-DR2 Molecules. REPLACEMENT OF THE HYDROPHOBIC TRANSMEMBRANE REGION BY A LEUCINE ZIPPER DIMERIZATION MOTIF ALLOWS THE ASSEMBLY AND SECRETION OF SOLUBLE DR alpha beta HETERODIMERS.

A. Kalandadze, M. Galleno, L. Foncerrada, J. L. Strominger, and K. W. Wucherpfennig (1996)
J. Biol. Chem. 271, 20156-20162
 |  Abstract »  |  Full Text »  |  PDF »

The Plasmid RK2 Initiation Protein Binds to the Origin of Replication as a Monomer.

A. E. Toukdarian, D. R. Helinski, and S. Perri (1996)
J. Biol. Chem. 271, 7072-7078
 |  Abstract »  |  Full Text »  |  PDF »

Genetic strategy for analyzing specificity of dimer formation: Escherichia coli cyclic AMP receptor protein mutant altered in its dimerization specificity..

J K Joung, E H Chung, G King, C Yu, A S Hirsh, and A Hochschild (1995)
Genes & Dev. 9, 2986-2996
 |  Abstract »  |  PDF »

The Effects of Interhelical Electrostatic Repulsions between Glutamic Acid Residues in Controlling the Dimerization and Stability of Two-stranded alpha-Helical Coiled-coils.

W. D. Kohn, O. D. Monera, C. M. Kay, and R. S. Hodges (1995)
J. Biol. Chem. 270, 25495-25506
 |  Abstract »  |  Full Text »  |  PDF »

Fos Leucine Zipper Variants with Increased Association Capacity.

D. Porte, P. Oertel-Buchheit, and M.čl. Granger-Schnarr (1995)
J. Biol. Chem. 270, 22721-22730
 |  Abstract »  |  Full Text »  |  PDF »

A switch between two-, three-, and four-stranded coiled coils in GCN4 leucine zipper mutants.

P. Harbury, T Zhang, P. Kim, and T Alber (1993)
Science 262, 1401-1407
 |  Abstract »  |  PDF »

Dimerization specificity of the leucine zipper-containing bZIP motif on DNA binding: prediction and rational design..

C R Vinson, T Hai, and S M Boyd (1993)
Genes & Dev. 7, 1047-1058
 |  Abstract »  |  PDF »

The HAT4 gene of Arabidopsis encodes a developmental regulator..

M Schena, A M Lloyd, and R W Davis (1993)
Genes & Dev. 7, 367-379
 |  Abstract »  |  PDF »

Altered specificity of DNA-binding proteins with transition metal dimerization domains.

B Cuenoud and A Schepartz (1993)
Science 259, 510-513
 |  Abstract »  |  PDF »

Tissue-specific RNA splicing generates an ankyrin-like domain that affects the dimerization and DNA-binding properties of a bHLH protein..

E S Klein, D M Simmons, L W Swanson, and M G Rosenfeld (1993)
Genes & Dev. 7, 55-71
 |  Abstract »  |  PDF »

Modulation of the dimerization of a transcriptional antiterminator protein by phosphorylation.

O Amster-Choder and A Wright (1992)
Science 257, 1395-1398
 |  Abstract »  |  PDF »

A Drosophila CREB/ATF transcriptional activator binds to both fat body- and liver-specific regulatory elements..

T Abel, R Bhatt, and T Maniatis (1992)
Genes & Dev. 6, 466-480
 |  Abstract »  |  PDF »

X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coil.

E. O'Shea, J. Klemm, P. Kim, and T Alber (1991)
Science 254, 539-544
 |  Abstract »  |  PDF »

Stress-induced expression of the Escherichia coli phage shock protein operon is dependent on sigma 54 and modulated by positive and negative feedback mechanisms..

L Weiner, J L Brissette, and P Model (1991)
Genes & Dev. 5, 1912-1923
 |  Abstract »  |  PDF »

The leucine zipper of TFE3 dictates helix-loop-helix dimerization specificity..

H Beckmann and T Kadesch (1991)
Genes & Dev. 5, 1057-1066
 |  Abstract »  |  PDF »

Max: a helix-loop-helix zipper protein that forms a sequence-specific DNA-binding complex with Myc.

E. Blackwood and R. Eisenman (1991)
Science 251, 1211-1217
 |  Abstract »  |  PDF »

A CDC6 Protein-binding Peptide Selected Using a Bacterial Two-hybrid-like System Is a Cell Cycle Inhibitor.

W. Zhu, R. S. Williams, and T. Kodadek (2000)
J. Biol. Chem. 275, 32098-32105
 |  Abstract »  |  Full Text »  |  PDF »

Zipper-mediated Oligomerization of the Mixed Lineage Kinase SPRK/MLK-3 Is Not Required for Its Activation by the GTPase cdc 42 but Is Necessary for Its Activation of the JNK Pathway. MONOMERIC SPRK L410P DOES NOT CATALYZE THE ACTIVATING PHOSPHORYLATION OF Thr258 OF MURINE MITOGEN-ACTIVATED PROTEIN KINASE KINASE 4.

P. O. Vacratsis and K. A. Gallo (2000)
J. Biol. Chem. 275, 27893-27900
 |  Abstract »  |  Full Text »  |  PDF »

The Putative Coiled Coil Domain of the phi 29 Terminal Protein Is a Major Determinant Involved in Recognition of the Origin of Replication.

A. Serna-Rico, B. Illana, M. Salas, and W. J. J. Meijer (2000)
J. Biol. Chem. 275, 40529-40538
 |  Abstract »  |  Full Text »  |  PDF »

Interactions within the Coiled-coil Domain of RetGC-1 Guanylyl Cyclase Are Optimized for Regulation Rather than for High Affinity.

V. Ramamurthy, C. Tucker, S. E. Wilkie, V. Daggett, D. M. Hunt, and J. B. Hurley (2001)
J. Biol. Chem. 276, 26218-26229
 |  Abstract »  |  Full Text »  |  PDF »

MACROH2A2, a New Member of the MACROH2A Core Histone Family.

C. Costanzi and J. R. Pehrson (2001)
J. Biol. Chem. 276, 21776-21784
 |  Abstract »  |  Full Text »  |  PDF »

Supramolecular Chemistry And Self-assembly Special Feature: Peptide-amphiphile nanofibers: A versatile scaffold for the preparation of self-assembling materials.

J. D. Hartgerink, E. Beniash, and S. I. Stupp (2002)
PNAS 99, 5133-5138
 |  Abstract »  |  Full Text »  |  PDF »

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