Science 30 November 1990: Vol. 250. no. 4985, pp. 1253 - 1256 DOI: 10.1126/science.1700866

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Articles

Identification of an Autoinhibitory Mechanism That Restricts C1 Domain-mediated Activation of the Rac-GAP {alpha}2-Chimaerin.

F. Colon-Gonzalez, F. C. Leskow, and M. G. Kazanietz (2008)
J. Biol. Chem. 283, 35247-35257
 |  Abstract »  |  Full Text »  |  PDF »

Phospholipase C{gamma}2 Mediates RANKL-stimulated Lymph Node Organogenesis and Osteoclastogenesis.

Y. Chen, X. Wang, L. Di, G. Fu, Y. Chen, L. Bai, J. Liu, X. Feng, J. M. McDonald, S. Michalek, et al. (2008)
J. Biol. Chem. 283, 29593-29601
 |  Abstract »  |  Full Text »  |  PDF »

(S)-Armepavine inhibits human peripheral blood mononuclear cell activation by regulating Itk and PLC{gamma} activation in a PI-3K-dependent manner.

C.-P. Liu, Y.-C. Kuo, C.-C. Shen, M.-H. Wu, J.-F. Liao, Y.-L. Lin, C.-F. Chen, and W.-J. Tsai (2007)
J. Leukoc. Biol. 81, 1276-1286
 |  Abstract »  |  Full Text »  |  PDF »

Differential Regulation of Human NK Cell-Mediated Cytotoxicity by the Tyrosine Kinase Itk.

D. Khurana, L. N. Arneson, R. A. Schoon, C. J. Dick, and P. J. Leibson (2007)
J. Immunol. 178, 3575-3582
 |  Abstract »  |  Full Text »  |  PDF »

Polyamines are required for phospholipase C-{gamma}1 expression promoting intestinal epithelial restitution after wounding.

J. N. Rao, L. Liu, T. Zou, B. S. Marasa, D. Boneva, S. R. Wang, D. L. Malone, D. J. Turner, and J.-Y. Wang (2007)
Am J Physiol Gastrointest Liver Physiol 292, G335-G343
 |  Abstract »  |  Full Text »  |  PDF »

Subcellular Localization and Biological Actions of Activated RSK1 Are Determined by Its Interactions with Subunits of Cyclic AMP-Dependent Protein Kinase.

D. Chaturvedi, H. M. Poppleton, T. Stringfield, A. Barbier, and T. B. Patel (2006)
Mol. Cell. Biol. 26, 4586-4600
 |  Abstract »  |  Full Text »  |  PDF »

Calcium-induced Human Keratinocyte Differentiation Requires src- and fyn-mediated Phosphatidylinositol 3-Kinase-dependent Activation of Phospholipase C-{gamma}1.

Z. Xie, P. A. Singleton, L. Y.W. Bourguignon, and D. D. Bikle (2005)
Mol. Biol. Cell 16, 3236-3246
 |  Abstract »  |  Full Text »  |  PDF »

Spatial and Functional Heterogeneity of Sphingolipid-rich Membrane Domains.

E. Kiyokawa, T. Baba, N. Otsuka, A. Makino, S. Ohno, and T. Kobayashi (2005)
J. Biol. Chem. 280, 24072-24084
 |  Abstract »  |  Full Text »  |  PDF »

Amplification of Ca2+ Signaling by Diacylglycerol-mediated Inositol 1,4,5-Trisphosphate Production.

C. Hisatsune, K. Nakamura, Y. Kuroda, T. Nakamura, and K. Mikoshiba (2005)
J. Biol. Chem. 280, 11723-11730
 |  Abstract »  |  Full Text »  |  PDF »

Intramolecular interaction between phosphorylated tyrosine-783 and the C-terminal Src homology 2 domain activates phospholipase C-{gamma}1.

B. Poulin, F. Sekiya, and S. G. Rhee (2005)
PNAS 102, 4276-4281
 |  Abstract »  |  Full Text »  |  PDF »

Integrin-dependent PLC-{gamma}1 phosphorylation mediates fibronectin-dependent adhesion.

D. Tvorogov, X.-J. Wang, R. Zent, and G. Carpenter (2005)
J. Cell Sci. 118, 601-610
 |  Abstract »  |  Full Text »  |  PDF »

Tec Kinases Mediate Sustained Calcium Influx via Site-specific Tyrosine Phosphorylation of the Phospholipase C{gamma} Src Homology 2-Src Homology 3 Linker.

L. A. Humphries, C. Dangelmaier, K. Sommer, K. Kipp, R. M. Kato, N. Griffith, I. Bakman, C. W. Turk, J. L. Daniel, and D. J. Rawlings (2004)
J. Biol. Chem. 279, 37651-37661
 |  Abstract »  |  Full Text »  |  PDF »

Phospholipase C-{gamma}1 is a guanine nucleotide exchange factor for dynamin-1 and enhances dynamin-1-dependent epidermal growth factor receptor endocytosis.

J. H. Choi, J. B. Park, S. S. Bae, S. Yun, H. S. Kim, W.-P. Hong, I.-S. Kim, J. H. Kim, M. Y. Han, S. H. Ryu, et al. (2004)
J. Cell Sci. 117, 3785-3795
 |  Abstract »  |  Full Text »  |  PDF »

Immunosuppressive and Anti-Inflammatory Effects of Nicotine Administered by Patch in an Animal Model.

R. Kalra, S. P. Singh, J. C. Pena-Philippides, R. J. Langley, S. Razani-Boroujerdi, and M. L. Sopori (2004)
Clin. Vaccine Immunol. 11, 563-568
 |  Abstract »  |  Full Text »  |  PDF »

The receptor tyrosine kinase MerTK activates phospholipase C {gamma}2 during recognition of apoptotic thymocytes by murine macrophages.

J. C. Todt, B. Hu, and J. L. Curtis (2004)
J. Leukoc. Biol. 75, 705-713
 |  Abstract »  |  Full Text »  |  PDF »

Epidermal growth factor activates cytosolic [Ca2+] elevations and subsequent membrane permeabilization in mouse cumulus-oocyte complexes.

J. B O'Donnell Jr, J. L Hill, and D. J Gross (2004)
Reproduction 127, 207-220
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of Protein Kinase C-Dependent Mitogen-Activated Protein Kinase p44/42 Signaling Pathway for Cross-Talk between Estradiol and Transforming Growth Factor-{beta}3 in Increasing Basic Fibroblast Growth Factor in Folliculostellate Cells.

K. Chaturvedi and D. K. Sarkar (2004)
Endocrinology 145, 706-715
 |  Abstract »  |  Full Text »  |  PDF »

Histone Deacetylase Inhibition by Sodium Butyrate Chemotherapy Ameliorates the Neurodegenerative Phenotype in Huntington's Disease Mice.

R. J. Ferrante, J. K. Kubilus, J. Lee, H. Ryu, A. Beesen, B. Zucker, K. Smith, N. W. Kowall, R. R. Ratan, R. Luthi-Carter, et al. (2003)
J. Neurosci. 23, 9418-9427
 |  Abstract »  |  Full Text »  |  PDF »

Rosmarinic acid inhibits Ca2+-dependent pathways of T-cell antigen receptor-mediated signaling by inhibiting the PLC-gamma 1 and Itk activity.

M.-A. Kang, S.-Y. Yun, and J. Won (2003)
Blood 101, 3534-3542
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of T Cell Activation and Tolerance by Phospholipase C{gamma}-1-Dependent Integrin Avidity Modulation.

A. D. Wells, Q.-H. Liu, B. Hondowicz, J. Zhang, L. A. Turka, and B. D. Freedman (2003)
J. Immunol. 170, 4127-4133
 |  Abstract »  |  Full Text »  |  PDF »

Chronic Self-Administration of Nicotine in Rats Impairs T Cell Responsiveness.

R. Kalra, S. P. Singh, D. Kracko, S. G. Matta, B. M. Sharp, and M. L. Sopori (2002)
J. Pharmacol. Exp. Ther. 302, 935-939
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Phospholipase Cgamma 2 by Tyrosine Phosphorylation.

F. Ozdener, C. Dangelmaier, B. Ashby, S. P. Kunapuli, and J. L. Daniel (2002)
Mol. Pharmacol. 62, 672-679
 |  Abstract »  |  Full Text »  |  PDF »

MAP Kinase Phosphatase As a Locus of Flexibility in a Mitogen-Activated Protein Kinase Signaling Network.

U. S. Bhalla, P. T. Ram, and R. Iyengar (2002)
Science 297, 1018-1023
 |  Abstract »  |  Full Text »  |  PDF »

Role of PLCgamma and Ca2+ in VEGF- and FGF-induced choroidal endothelial cell proliferation.

A. P. McLaughlin and G. W. De Vries (2001)
Am J Physiol Cell Physiol 281, C1448-C1456
 |  Abstract »  |  Full Text »  |  PDF »

Four Tyrosine Residues in Phospholipase C-gamma 2, Identified as Btk-dependent Phosphorylation Sites, Are Required for B Cell Antigen Receptor-coupled Calcium Signaling.

D. Watanabe, S. Hashimoto, M. Ishiai, M. Matsushita, Y. Baba, T. Kishimoto, T. Kurosaki, and S. Tsukada (2001)
J. Biol. Chem. 276, 38595-38601
 |  Abstract »  |  Full Text »  |  PDF »

Protein Tyrosine Phosphatase CD148-Mediated Inhibition of T-Cell Receptor Signal Transduction Is Associated with Reduced LAT and Phospholipase C{gamma}1 Phosphorylation.

J. E. Baker, R. Majeti, S. G. Tangye, and A. Weiss (2001)
Mol. Cell. Biol. 21, 2393-2403
 |  Abstract »  |  Full Text »

Antigen Receptor Proximal Signaling in Splenic B-2 Cell Subsets.

X. Li, F. Martin, A. M. Oliver, J. F. Kearney, and R. H. Carter (2001)
J. Immunol. 166, 3122-3129
 |  Abstract »  |  Full Text »  |  PDF »

The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer.

E. Middleton Jr., C. Kandaswami, and T. C. Theoharides (2000)
Pharmacol. Rev. 52, 673-751
 |  Abstract »  |  Full Text »  |  PDF »

Signaling Mechanisms of Altered Cellular Responses in Trauma, Burn, and Sepsis: Role of Ca2+.

M. M. Sayeed (2000)
Arch Surg 135, 1432-1442
 |  Abstract »  |  Full Text »  |  PDF »

ICAM-1-Coupled Cytoskeletal Rearrangements and Transendothelial Lymphocyte Migration Involve Intracellular Calcium Signaling in Brain Endothelial Cell Lines.

S. Etienne-Manneville, J.-B. Manneville, P. Adamson, B. Wilbourn, J. Greenwood, and P.-O. Couraud (2000)
J. Immunol. 165, 3375-3383
 |  Abstract »  |  Full Text »  |  PDF »

Hydroxychloroquine inhibits calcium signals in T cells: a new mechanism to explain its immunomodulatory properties.

F. D. Goldman, A. L. Gilman, C. Hollenback, R. M. Kato, B. A. Premack, and D. J. Rawlings (2000)
Blood 95, 3460-3466
 |  Abstract »  |  Full Text »  |  PDF »

Analysis of receptor signaling pathways by mass spectrometry: Identification of Vav-2 as a substrate of the epidermal and platelet-derived growth factor receptors.

A. Pandey, A. V. Podtelejnikov, B. Blagoev, X. R. Bustelo, M. Mann, and H. F. Lodish (2000)
PNAS 97, 179-184
 |  Abstract »  |  Full Text »  |  PDF »

Acceleration of trophoblast differentiation by heparin-binding EGF-like growth factor is dependent on the stage-specific activation of calcium influx by ErbB receptors in developing mouse blastocysts.

J Wang, L Mayernik, J. Schultz, and D. Armant (2000)
Development 127, 33-44
 |  Abstract »  |  PDF »

Inhibition of Epidermal Growth Factor Receptor-Associated Tyrosine Phosphorylation in Human Carcinomas with CP-358,774: Dynamics of Receptor Inhibition In Situ and Antitumor Effects in Athymic Mice.

V. A. Pollack, D. M. Savage, D. A. Baker, K. E. Tsaparikos, D. E. Sloan, J. D. Moyer, E. G. Barbacci, L. R. Pustilnik, T. A. Smolarek, J. A. Davis, et al. (1999)
J. Pharmacol. Exp. Ther. 291, 739-748
 |  Abstract »  |  Full Text »

Functional Independence and Interdependence of the Src Homology Domains of Phospholipase C-gamma 1 in B-Cell Receptor Signal Transduction.

K. E. DeBell, B. A. Stoica, M.-C. Veri, A. Di Baldassarre, S. Miscia, L. J. Graham, B. L. Rellahan, M. Ishiai, T. Kurosaki, and E. Bonvini (1999)
Mol. Cell. Biol. 19, 7388-7398
 |  Abstract »  |  Full Text »  |  PDF »

Phospholipase C-delta 1 Contains a Functional Nuclear Export Signal Sequence.

M. Yamaga, M. Fujii, H. Kamata, H. Hirata, and H. Yagisawa (1999)
J. Biol. Chem. 274, 28537-28541
 |  Abstract »  |  Full Text »  |  PDF »

Inefficient Phospholipase C Activation and Reduced Lck Expression Characterize the Signaling Defect of Umbilical Cord T Lymphocytes.

S. Miscia, A. Di Baldassarre, G. Sabatino, E. Bonvini, R. A. Rana, M. Vitale, V. Di Valerio, and F. A. Manzoli (1999)
J. Immunol. 163, 2416-2424
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Association of Phospholipase C-{gamma}2 Src Homology 2 Domains with BLNK Is Critical for B Cell Antigen Receptor Signaling.

M. Ishiai, H. Sugawara, M. Kurosaki, and T. Kurosaki (1999)
J. Immunol. 163, 1746-1749
 |  Abstract »  |  Full Text »  |  PDF »

Focal adhesion kinase promotes phospholipase C-gamma 1 activity.

X. Zhang, A. Chattopadhyay, Q.-s. Ji, J. D. Owen, P. J. Ruest, G. Carpenter, and S. K. Hanks (1999)
PNAS 96, 9021-9026
 |  Abstract »  |  Full Text »  |  PDF »

Physiological Requirement for Both SH2 Domains for Phospholipase C-gamma 1 Function and Interaction with Platelet-Derived Growth Factor Receptors.

Q.-s. Ji, A. Chattopadhyay, M. Vecchi, and G. Carpenter (1999)
Mol. Cell. Biol. 19, 4961-4970
 |  Abstract »  |  Full Text »  |  PDF »

A Role for Neutral Sphingomyelinase-mediated Ceramide Production in T Cell Receptor-induced Apoptosis and Mitogen-activated Protein Kinase-mediated Signal Transduction.

L. Tonnetti, M.-C. Veri, E. Bonvini, and L. D'Adamio (1999)
J. Exp. Med. 189, 1581-1589
 |  Abstract »  |  Full Text »  |  PDF »

Activation of C3G Guanine Nucleotide Exchange Factor for Rap1 by Phosphorylation of Tyrosine 504.

T. Ichiba, Y. Hashimoto, M. Nakaya, Y. Kuraishi, S. Tanaka, T. Kurata, N. Mochizuki, and M. Matsuda (1999)
J. Biol. Chem. 274, 14376-14381
 |  Abstract »  |  Full Text »  |  PDF »

Role of PI3-kinase in the development of interstitial cells and pacemaking in murine gastrointestinal smooth muscle.

S. M Ward, M.-F. Brennan, V. M Jackson, and K. M Sanders (1999)
J. Physiol. 516, 835-846
 |  Abstract »  |  Full Text »  |  PDF »

Action of Phosphatidylinositol-specific Phospholipase Cgamma 1 on Soluble and Micellar Substrates. SEPARATING EFFECTS ON CATALYSIS FROM MODULATION OF THE SURFACE.

C. Zhou, D. Horstman, G. Carpenter, and M. F. Roberts (1999)
J. Biol. Chem. 274, 2786-2793
 |  Abstract »  |  Full Text »  |  PDF »

Emergent Properties of Networks of Biological Signaling Pathways.

U. S. Bhalla and Ravi Iyengar (1999)
Science 283, 381-387
 |  Abstract »  |  Full Text »

Expression of Thrombomodulin in Atherosclerotic Lesions and Mitogenic Activity of Recombinant Thrombomodulin in Vascular Smooth Muscle Cells.

G. Tohda, K. Oida, Y. Okada, S. Kosaka, E. Okada, S. Takahashi, H. Ishii, and I. Miyamori (1998)
Arterioscler Thromb Vasc Biol 18, 1861-1869
 |  Abstract »  |  Full Text »  |  PDF »

A p56lck-independent Pathway of CD2 Signaling Involves Jun Kinase.

R. Sunder-Plassmann and E. L. Reinherz (1998)
J. Biol. Chem. 273, 24249-24257
 |  Abstract »  |  Full Text »  |  PDF »

Activation of Lyn, Blk, and Btk But Not Syk in CD72-Stimulated B Lymphocytes.

C. Venkataraman, N. Muthusamy, S. Muthukkumar, and S. Bondada (1998)
J. Immunol. 160, 3322-3329
 |  Abstract »  |  Full Text »  |  PDF »

Wortmannin-Sensitive Phosphorylation, Translocation, and Activation of PLCgamma 1, but Not PLCgamma 2, in Antigen-stimulated RBL-2H3 Mast Cells.

S. A. Barker, K. K. Caldwell, J. R. Pfeiffer, and B. S. Wilson (1998)
Mol. Biol. Cell 9, 483-496
 |  Abstract »  |  Full Text »

Prostaglandin E2 Modulation of p59fyn Tyrosine Kinase in T Lymphocytes During Sepsis.

M. A. Choudhry, S. Uddin, and M. M. Sayeed (1998)
J. Immunol. 160, 929-935
 |  Abstract »  |  Full Text »  |  PDF »

Qualitative Regulation of B Cell Antigen Receptor Signaling by CD19: Selective Requirement for PI3-Kinase Activation, Inositol-1,4,5-Trisphosphate Production and Ca2+ Mobilization.

A. M. Buhl, C. M. Pleiman, R. C. Rickert, and J. C. Cambier (1997)
J. Exp. Med. 186, 1897-1910
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Two Tyrosine Phosphoproteins, pp70 and pp68, Which Interact with Phospholipase Cgamma , Grb2, and Vav after B Cell Antigen Receptor Activation.

C. Fu and A. C. Chan (1997)
J. Biol. Chem. 272, 27362-27368
 |  Abstract »  |  Full Text »  |  PDF »

Angiotensin II Stimulates Tyrosine Phosphorylation of Phospholipase C-{gamma}–Associated Proteins : Characterization of a c-Src–Dependent 97-kD Protein in Vascular Smooth Muscle Cells.

U. Schmitz, M. Ishida, and B. C. Berk (1997)
Circ. Res. 81, 550-557
 |  Abstract »  |  Full Text »

Regulation of Mouse Skeletal Muscle L-Type Ca2+ Channel by Activation of the Insulin-Like Growth Factor-1 Receptor.

O. Delbono, M. Renganathan, and M. L. Messi (1997)
J. Neurosci. 17, 6918-6928
 |  Abstract »  |  Full Text »  |  PDF »

Gelsolin Modulates Phospholipase C Activity In Vivo through Phospholipid Binding.

H.-q. Sun, K.-m. Lin, and H. L. Yin (1997)
J. Cell Biol. 138, 811-820
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Receptor-induced Phosphorylation of Sos Requires Activity of CD45, Lck, and Protein Kinase C, but Not ERK.

H. Zhao, Y.-Y. Li, R. V. Fucini, S. E. Ross, J. E. Pessin, and G. A. Koretzky (1997)
J. Biol. Chem. 272, 21625-21634
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of Lnk. AN ADAPTOR PROTEIN EXPRESSED IN LYMPHOCYTES.

S. Takaki, J. D. Watts, K. A. Forbush, N. T. Nguyen, J. Hayashi, J. Alberola-Ila, R. Aebersold, and R. M. Perlmutter (1997)
J. Biol. Chem. 272, 14562-14570
 |  Abstract »  |  Full Text »  |  PDF »

Subsets of Epidermal Growth Factor Receptors during Activation and Endocytosis.

D. R. Emlet, D. K. Moscatello, L. B. Ludlow, and A. J. Wong (1997)
J. Biol. Chem. 272, 4079-4086
 |  Abstract »  |  Full Text »  |  PDF »

Killer Cell Inhibitory Receptor Recognition of Human Leukocyte Antigen (HLA) Class I Blocks Formation of a pp36/PLC-{gamma} Signaling Complex in Human Natural Killer (NK) Cells.

N. M. Valiante, J. H. Phillips, L. L. Lanier, and P. Parham (1996)
J. Exp. Med. 184, 2243-2250
 |  Abstract »  |  Full Text »  |  PDF »

Differential Ca2+ Signaling Induced by Activation of the Epidermal Growth Factor and Nerve Growth Factor Receptors.

I. Tinhofer, K. Maly, P. Dietl, F. Hochholdinger, S. Mayr, A. Obermeier, and H. H. Grunicke (1996)
J. Biol. Chem. 271, 30505-30509
 |  Abstract »  |  Full Text »  |  PDF »

Glucose-induced Tyrosine Phosphorylation of p125 in Beta Cells and Pancreatic Islets. A NOVEL PROXIMAL SIGNAL IN INSULIN SECRETION.

R. J. Konrad, R. M. Dean, R. A. Young, P. C. Billings, and B. A. Wolf (1996)
J. Biol. Chem. 271, 24179-24186
 |  Abstract »  |  Full Text »  |  PDF »

Human Cancer Cells Exhibit Protein Kinase C-dependent c-erbB-2 Transmodulation That Correlates with Phosphatase Sensitivity and Kinase Activity.

X. Ouyang, T. Gulliford, H. Zhang, G. C. Huang, and R. Epstein (1996)
J. Biol. Chem. 271, 21786-21792
 |  Abstract »  |  Full Text »  |  PDF »

Dopamine D1A Receptor Regulation of Phospholipase C Isoform.

P.-Y. Yu, GilbertM. Eisner, I. Yamaguchi, M.M. Mouradian, RobinA. Felder, and PedroA. Jose (1996)
J. Biol. Chem. 271, 19503-19508
 |  Abstract »  |  Full Text »  |  PDF »

The Fcgamma RII Receptor Triggers pp125FAK Phosphorylation in Platelets.

B. Haimovich, C. Regan, L. DiFazio, E. Ginalis, P. Ji, U. Purohit, R. B. Rowley, J. Bolen, and R. Greco (1996)
J. Biol. Chem. 271, 16332-16337
 |  Abstract »  |  Full Text »  |  PDF »

Differential Translocation of Phospholipase C Isozymes to Integrin-mediated Cytoskeletal Complexes in Thrombin-stimulated Human Platelets.

Y. Banno, S. Nakashima, M. Ohzawa, and Y. Nozawa (1996)
J. Biol. Chem. 271, 14989-14994
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Characterization of the Di-leucine-based Internalization Motif of the T Cell Receptor.

J. Dietrich, X. Hou, A.-M. K. Wegener, L.Øs. Pedersen, N. Odum, and C. Geisler (1996)
J. Biol. Chem. 271, 11441-11448
 |  Abstract »  |  Full Text »  |  PDF »

Rac-dependent and -independent Pathways Mediate Growth Factor-induced Ca[IMAGE] Influx.

M. P. Peppelenbosch, L. G. J. Tertoolen, A. M. M. de Vries-Smits, R.-G. Qiu, L. M'Rabet, M. H. Symons, S. W. de Laat, and J. L. Bos (1996)
J. Biol. Chem. 271, 7883-7886
 |  Abstract »  |  Full Text »  |  PDF »

EJ-Ras Inhibits Phospholipase C{gamma}1 but Not Actin Polymerization Induced by Platelet-Derived Growth Factor-BB via Phosphatidylinositol 3-Kinase.

A. W. Heldman, D. E. Kandzari, R. W. Tucker, L. E. Crawford, E. R. Fearon, K. S. Koblan, and P. J. Goldschmidt-Clermont (1996)
Circ. Res. 78, 312-321
 |  Abstract »  |  Full Text »

Demonstration of a Direct Interaction between p56[IMAGE] and the Cytoplasmic Domain of CD45 in Vitro.

D. H. W. Ng, J. D. Watts, R. Aebersold, and P. Johnson (1996)
J. Biol. Chem. 271, 1295-1300
 |  Abstract »  |  Full Text »  |  PDF »

Association of Polyomavirus Middle Tumor Antigen with Phospholipase C-[IMAGE]1.

W. Su, W. Liu, B. S. Schaffhausen, and T. M. Roberts (1995)
J. Biol. Chem. 270, 12331-12334
 |  Abstract »  |  Full Text »  |  PDF »

Requirement for phosphatidylinositol transfer protein in epidermal growth factor signaling.

A Kauffmann-Zeh, G. Thomas, A Ball, S Prosser, E Cunningham, S Cockcroft, and J. Hsuan (1995)
Science 268, 1188-1190
 |  Abstract »  |  PDF »

Association of p72[IMAGE] with the src Homology-2 (SH2) Domains of PLC[IMAGE]1 in B Lymphocytes.

A. L. Sillman and J. G. Monroe (1995)
J. Biol. Chem. 270, 11806-11811
 |  Abstract »  |  Full Text »  |  PDF »

Demonstration of Functionally Different Interactions between Phospholipase C-[IMAGE] and the Two Types of Platelet-derived Growth Factor Receptors.

A. Eriksson, E. Nånberg, L. Rönnstrand, U. Engström, U. Hellman, E. Rupp, G. Carpenter, C.-H. Heldin, and L. Claesson-Welsh (1995)
J. Biol. Chem. 270, 7773-7781
 |  Abstract »  |  Full Text »  |  PDF »

Muscarinic Regulation of Alzheimer's Disease Amyloid Precursor Protein Secretion and Amyloid beta-Protein Production in Human Neuronal NT2N Cells.

B. A. Wolf, A. M. Wertkin, Y. C. Jolly, R. P. Yasuda, B. B. Wolfe, R. J. Konrad, D. Manning, S. Ravi, J. R. Williamson, and V. M.-Y. Lee (1995)
J. Biol. Chem. 270, 4916-4922
 |  Abstract »  |  Full Text »  |  PDF »

Epidermal growth factor induces rapid and transient association of phospholipase C-gamma 1 with EGF-receptor and filamentous actin at membrane ruffles of A431 cells.

M Diakonova, B Payrastre, A. van Velzen, W. Hage, P. van Bergen en Henegouwen, J Boonstra, F. Cremers, and B. Humbel (1995)
J. Cell Sci. 108, 2499-2509
 |  Abstract »  |  PDF »

Rescue of signaling by a chimeric protein containing the cytoplasmic domain of CD45.

R. Hovis, J. Donovan, M. Musci, D. Motto, F. Goldman, S. Ross, and G. Koretzky (1993)
Science 260, 544-546
 |  Abstract »  |  PDF »

Activation of a phosphotyrosine phosphatase by tyrosine phosphorylation.

W Vogel, R Lammers, J Huang, and A Ullrich (1993)
Science 259, 1611-1614
 |  Abstract »  |  PDF »

Tyrosine phosphorylation of CD22 during B cell activation.

R. Schulte, M. Campbell, W. Fischer, and B. Sefton (1992)
Science 258, 1001-1004
 |  Abstract »  |  PDF »

No requirement for p56lck in the antigen-stimulated clonal deletion of thymocytes.

K Nakayama and D. Loh (1992)
Science 257, 94-96
 |  Abstract »  |  PDF »

Role of SH2-containing Proteins in Cellular Signaling by Receptor Tyrosine Kinases.

J. Schlessinger, M. Mohammadi, B. Margolis, and A. Ullrich (1992)
Cold Spring Harb Symp Quant Biol 57, 67-74
 |  Abstract »  |  PDF »

Phosphatidylinositol-3 Kinase and Growth Regulation.

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